RSPH10B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.82753415
2sperm motility (GO:0030317)8.78422790
3fusion of sperm to egg plasma membrane (GO:0007342)8.16002212
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.14883728
5motile cilium assembly (GO:0044458)7.89631011
6acrosome assembly (GO:0001675)7.45508880
7multicellular organism reproduction (GO:0032504)7.12059003
8acrosome reaction (GO:0007340)6.96397306
9sperm-egg recognition (GO:0035036)6.88325084
10cell wall macromolecule metabolic process (GO:0044036)6.71785241
11cell wall macromolecule catabolic process (GO:0016998)6.71785241
12axoneme assembly (GO:0035082)6.65347382
13ventricular system development (GO:0021591)6.59948505
14plasma membrane fusion (GO:0045026)6.50530211
15regulation of cilium movement (GO:0003352)6.48382548
16binding of sperm to zona pellucida (GO:0007339)6.17405091
17cell-cell recognition (GO:0009988)6.15372019
18spermatid development (GO:0007286)6.03725490
19sperm capacitation (GO:0048240)5.96854817
20piRNA metabolic process (GO:0034587)5.86851342
21reproduction (GO:0000003)5.82886892
22GTP biosynthetic process (GO:0006183)5.41799016
23male meiosis (GO:0007140)5.29326285
24negative regulation of inclusion body assembly (GO:0090084)5.12937442
25single fertilization (GO:0007338)5.08229347
26nucleoside diphosphate phosphorylation (GO:0006165)4.92517727
27microtubule severing (GO:0051013)4.87253288
28UTP biosynthetic process (GO:0006228)4.74957028
29intraciliary transport (GO:0042073)4.72947070
30synaptonemal complex organization (GO:0070193)4.64539783
31UTP metabolic process (GO:0046051)4.28837763
32fertilization (GO:0009566)4.26956374
33centriole assembly (GO:0098534)4.24254658
34calcium ion-dependent exocytosis (GO:0017156)4.20344172
35spermatogenesis (GO:0007283)4.13884182
36male gamete generation (GO:0048232)4.11996762
37cilium organization (GO:0044782)4.10944572
38synaptonemal complex assembly (GO:0007130)4.08655364
39microtubule-based movement (GO:0007018)4.04922640
40fucose catabolic process (GO:0019317)4.01414730
41L-fucose metabolic process (GO:0042354)4.01414730
42L-fucose catabolic process (GO:0042355)4.01414730
43regulation of microtubule-based movement (GO:0060632)4.00822469
44protein polyglutamylation (GO:0018095)3.92679246
45cilium assembly (GO:0042384)3.89925060
46left/right axis specification (GO:0070986)3.86655129
47spermatid nucleus differentiation (GO:0007289)3.82057554
48gamete generation (GO:0007276)3.80986905
49protein localization to cilium (GO:0061512)3.78602422
50regulation of inclusion body assembly (GO:0090083)3.75428447
51behavioral response to nicotine (GO:0035095)3.75160544
52CTP metabolic process (GO:0046036)3.69553825
53CTP biosynthetic process (GO:0006241)3.69553825
54cell recognition (GO:0008037)3.67578734
55left/right pattern formation (GO:0060972)3.66781950
56DNA methylation involved in gamete generation (GO:0043046)3.66547284
57guanosine-containing compound biosynthetic process (GO:1901070)3.65794462
58centriole replication (GO:0007099)3.64878623
59protein localization to synapse (GO:0035418)3.64579150
60nonmotile primary cilium assembly (GO:0035058)3.63664064
61cellular component assembly involved in morphogenesis (GO:0010927)3.57610141
62retinal cone cell development (GO:0046549)3.55165676
63cilium morphogenesis (GO:0060271)3.50673446
64vitamin transmembrane transport (GO:0035461)3.50452262
65one-carbon compound transport (GO:0019755)3.45904976
66cellular process involved in reproduction in multicellular organism (GO:0022412)3.45014280
67cellular potassium ion homeostasis (GO:0030007)3.44427229
68male meiosis I (GO:0007141)3.43872814
69microtubule polymerization or depolymerization (GO:0031109)3.40414048
70microtubule bundle formation (GO:0001578)3.39193766
71germ cell development (GO:0007281)3.39169329
72response to xenobiotic stimulus (GO:0009410)3.36163733
73calcium ion import (GO:0070509)3.32361706
74pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.32019380
75photoreceptor cell maintenance (GO:0045494)3.30314305
76negative regulation of T cell differentiation in thymus (GO:0033085)3.28776142
77organic cation transport (GO:0015695)3.28095523
78pyrimidine-containing compound transmembrane transport (GO:0072531)3.25423118
79membrane depolarization during action potential (GO:0086010)3.13385116
80primary alcohol catabolic process (GO:0034310)3.12000464
81determination of left/right symmetry (GO:0007368)3.07576898
82pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.06363534
83exogenous drug catabolic process (GO:0042738)3.04903988
84multicellular organismal reproductive process (GO:0048609)3.00378377
85phosphatidylethanolamine biosynthetic process (GO:0006646)2.99344093
86smoothened signaling pathway (GO:0007224)2.96455322
87phosphatidylethanolamine metabolic process (GO:0046337)2.95756036
88detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.94921048
89lateral ventricle development (GO:0021670)2.94111848
90pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.93092745
91nucleotide phosphorylation (GO:0046939)2.92010628
92determination of bilateral symmetry (GO:0009855)2.87975118
93vocalization behavior (GO:0071625)2.87383930
94rRNA catabolic process (GO:0016075)2.86069957
95negative regulation of organelle assembly (GO:1902116)2.85721494
96retinal rod cell development (GO:0046548)2.85077172
97diterpenoid biosynthetic process (GO:0016102)2.83577916
98indole-containing compound catabolic process (GO:0042436)2.82662061
99indolalkylamine catabolic process (GO:0046218)2.82662061
100tryptophan catabolic process (GO:0006569)2.82662061
101specification of symmetry (GO:0009799)2.80177553
102meiotic cell cycle (GO:0051321)2.77508071
103regulation of collateral sprouting (GO:0048670)2.75350849
104positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.75180388
105positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.74292891
106ubiquinone biosynthetic process (GO:0006744)2.74163024
107meiotic nuclear division (GO:0007126)2.71581309
108positive regulation of dendritic spine morphogenesis (GO:0061003)2.71078446
109lung epithelium development (GO:0060428)2.71041234
110indolalkylamine metabolic process (GO:0006586)2.70894937
111cornea development in camera-type eye (GO:0061303)2.70022205
112lactate metabolic process (GO:0006089)2.68599134
113aldehyde catabolic process (GO:0046185)2.68072531
114drug catabolic process (GO:0042737)2.66668625
115synaptic vesicle exocytosis (GO:0016079)2.66635515
116cell projection assembly (GO:0030031)2.66433204
117chromosome organization involved in meiosis (GO:0070192)2.66201033
118microtubule depolymerization (GO:0007019)2.64089698
119ethanol metabolic process (GO:0006067)2.61107269
120detection of light stimulus involved in visual perception (GO:0050908)2.60586512
121detection of light stimulus involved in sensory perception (GO:0050962)2.60586512
122kynurenine metabolic process (GO:0070189)2.60574227
123response to pheromone (GO:0019236)2.59479785
124layer formation in cerebral cortex (GO:0021819)2.59373779
125tryptophan metabolic process (GO:0006568)2.57151608
126tolerance induction (GO:0002507)2.55523641
127regulation of synaptic vesicle exocytosis (GO:2000300)2.53338094
128cellular ketone body metabolic process (GO:0046950)2.53153116
129spinal cord motor neuron differentiation (GO:0021522)2.52569854
130glycolytic process (GO:0006096)2.51537383
131meiosis I (GO:0007127)2.50543992
132ubiquinone metabolic process (GO:0006743)2.49803821
133sodium ion export (GO:0071436)2.49584122
134retinoic acid metabolic process (GO:0042573)2.49485858
135positive regulation of CREB transcription factor activity (GO:0032793)2.48439798
136organelle assembly (GO:0070925)2.47987267
137regulation of germinal center formation (GO:0002634)2.47692684
138neural tube formation (GO:0001841)2.46948067
139G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.45147677
140regulation of response to osmotic stress (GO:0047484)2.44060732
141regulation of meiosis I (GO:0060631)2.43614183
142gamma-aminobutyric acid signaling pathway (GO:0007214)2.43595052
143pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.42370319
144neuron cell-cell adhesion (GO:0007158)2.41164933
145potassium ion homeostasis (GO:0055075)2.41145602
146cytoplasmic microtubule organization (GO:0031122)2.39246585
147locomotory exploration behavior (GO:0035641)2.39163448
148DNA deamination (GO:0045006)2.39130337
149regulation of short-term neuronal synaptic plasticity (GO:0048172)2.38548150
150preassembly of GPI anchor in ER membrane (GO:0016254)2.38471664
151glutamate secretion (GO:0014047)2.37507007
152brain morphogenesis (GO:0048854)2.37390214
153benzene-containing compound metabolic process (GO:0042537)2.36414829
154terpenoid biosynthetic process (GO:0016114)2.33365563
155regulation of interleukin-5 production (GO:0032674)2.32448050
156cilium or flagellum-dependent cell motility (GO:0001539)12.7273332
157axonemal dynein complex assembly (GO:0070286)11.1746534
158cilium movement (GO:0003341)11.0014992

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.96483752
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.98337510
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.82425744
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.63686138
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.95242635
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.35789326
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.28986962
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09733523
9REST_21632747_ChIP-Seq_MESCs_Mouse2.09539974
10GBX2_23144817_ChIP-Seq_PC3_Human2.09366090
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.06829847
12EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.00223567
13TAF15_26573619_Chip-Seq_HEK293_Human1.95283564
14IGF1R_20145208_ChIP-Seq_DFB_Human1.92252261
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.84806580
16CBX2_27304074_Chip-Seq_ESCs_Mouse1.81035095
17DROSHA_22980978_ChIP-Seq_HELA_Human1.80441380
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.75383108
19ZNF274_21170338_ChIP-Seq_K562_Hela1.70105952
20RNF2_27304074_Chip-Seq_NSC_Mouse1.59791867
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59400104
22GATA1_26923725_Chip-Seq_HPCs_Mouse1.58336862
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58092248
24EWS_26573619_Chip-Seq_HEK293_Human1.54965266
25SMAD4_21799915_ChIP-Seq_A2780_Human1.54706299
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.54346730
27SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.53793748
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.52784198
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50591761
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.49392865
31TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.48180667
32CBP_20019798_ChIP-Seq_JUKART_Human1.47995177
33IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.47995177
34FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.46103666
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.45073820
36MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.42410195
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.41871085
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.41871085
39TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41429355
40NCOR_22424771_ChIP-Seq_293T_Human1.41118782
41TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40785791
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40016860
43ETV1_20927104_ChIP-Seq_GIST48_Human1.39638511
44TP53_22573176_ChIP-Seq_HFKS_Human1.39262078
45VDR_22108803_ChIP-Seq_LS180_Human1.38483420
46IRF1_19129219_ChIP-ChIP_H3396_Human1.37376217
47SALL1_21062744_ChIP-ChIP_HESCs_Human1.36461476
48TCF4_22108803_ChIP-Seq_LS180_Human1.35455976
49KDM2B_26808549_Chip-Seq_REH_Human1.35281047
50KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.34696465
51SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.34562024
52WDR5_24793694_ChIP-Seq_LNCAP_Human1.34509019
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34302422
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.34286205
55EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.33891521
56* GATA3_21878914_ChIP-Seq_MCF-7_Human1.33577674
57PHF8_20622853_ChIP-Seq_HELA_Human1.33200834
58FLI1_21867929_ChIP-Seq_TH2_Mouse1.32688504
59MTF2_20144788_ChIP-Seq_MESCs_Mouse1.31949967
60SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.31412198
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.30931134
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.30254622
63REST_18959480_ChIP-ChIP_MESCs_Mouse1.28924732
64ER_23166858_ChIP-Seq_MCF-7_Human1.28409064
65AR_21572438_ChIP-Seq_LNCaP_Human1.27218853
66ELK4_26923725_Chip-Seq_MESODERM_Mouse1.27048784
67MYC_19829295_ChIP-Seq_ESCs_Human1.26734068
68RBPJ_21746931_ChIP-Seq_IB4_Human1.25290755
69SOX2_19829295_ChIP-Seq_ESCs_Human1.24896855
70NANOG_19829295_ChIP-Seq_ESCs_Human1.24896855
71RUNX2_22187159_ChIP-Seq_PCA_Human1.24864025
72NANOG_18555785_Chip-Seq_ESCs_Mouse1.24484389
73ETV2_25802403_ChIP-Seq_MESCs_Mouse1.23805730
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22881766
75PRDM14_20953172_ChIP-Seq_ESCs_Human1.21495881
76P300_19829295_ChIP-Seq_ESCs_Human1.21160299
77HOXB7_26014856_ChIP-Seq_BT474_Human1.21119470
78AR_20517297_ChIP-Seq_VCAP_Human1.20944345
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20847139
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20847139
81TCF4_23295773_ChIP-Seq_U87_Human1.20837029
82PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20784391
83FUS_26573619_Chip-Seq_HEK293_Human1.20411612
84* ERA_21632823_ChIP-Seq_H3396_Human1.20268914
85FOXA1_21572438_ChIP-Seq_LNCaP_Human1.19728511
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19559522
87NANOG_20526341_ChIP-Seq_ESCs_Human1.18679262
88PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.17959741
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.17860418
90SMAD3_21741376_ChIP-Seq_EPCs_Human1.17479368
91STAT3_23295773_ChIP-Seq_U87_Human1.17241544
92SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.16301096
93E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.16221583
94TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.16054589
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15916547
96CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.15631321
97SMRT_27268052_Chip-Seq_Bcells_Human1.14955910
98RNF2_27304074_Chip-Seq_ESCs_Mouse1.14205331
99HNFA_21074721_ChIP-Seq_CACO-2_Human1.13864197
100NFYB_21822215_ChIP-Seq_K562_Human1.13713871
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13538423
102GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13290061
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12806485
104NFE2_27457419_Chip-Seq_LIVER_Mouse1.12702165
105TBL1_22424771_ChIP-Seq_293T_Human1.12261527
106CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.12167450
107EZH2_27304074_Chip-Seq_ESCs_Mouse1.10143584
108CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.09647783
109POU3F2_20337985_ChIP-ChIP_501MEL_Human1.09600427
110GATA6_21074721_ChIP-Seq_CACO-2_Human1.09303595
111RARB_27405468_Chip-Seq_BRAIN_Mouse1.09299679
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08845834
113NFYA_21822215_ChIP-Seq_K562_Human1.08516925
114CBX2_22325352_ChIP-Seq_293T-Rex_Human1.08405921
115TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08168134
116MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.07846356
117GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.07479939
118AR_25329375_ChIP-Seq_VCAP_Human1.07402782
119CDX2_22108803_ChIP-Seq_LS180_Human1.07315589
120* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07270169
121TAF2_19829295_ChIP-Seq_ESCs_Human1.07208483
122OCT4_20526341_ChIP-Seq_ESCs_Human1.06992198
123PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06013994
124SMAD4_21741376_ChIP-Seq_EPCs_Human1.05348852
125PIAS1_25552417_ChIP-Seq_VCAP_Human1.03999217
126RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03809334
127P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03427292
128CMYC_18555785_Chip-Seq_ESCs_Mouse1.03383950
129JARID2_20064375_ChIP-Seq_MESCs_Mouse1.03194050
130BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03091147
131GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02881754
132P53_22387025_ChIP-Seq_ESCs_Mouse1.02879490
133AUTS2_25519132_ChIP-Seq_293T-REX_Human1.02302463
134STAT1_20625510_ChIP-Seq_HELA_Human1.01566990
135MYC_18940864_ChIP-ChIP_HL60_Human1.01371154
136AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00226754
137SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.99010863
138UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98557840
139SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.97963131
140RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97141732
141OCT4_18555785_Chip-Seq_ESCs_Mouse0.96439825
142CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.96265265
143SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.95958474
144SOX9_26525672_Chip-Seq_HEART_Mouse0.95917671
145P300_18555785_Chip-Seq_ESCs_Mouse0.95822992
146JARID2_20075857_ChIP-Seq_MESCs_Mouse0.95275424
147SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95083180
148PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.94986542
149ARNT_22903824_ChIP-Seq_MCF-7_Human0.94813445
150SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.94719657
151SMAD3_21741376_ChIP-Seq_ESCs_Human0.94329219
152BCAT_22108803_ChIP-Seq_LS180_Human0.94007369

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.91430063
2MP0002653_abnormal_ependyma_morphology4.39599404
3MP0008875_abnormal_xenobiotic_pharmacok4.27036833
4MP0003698_abnormal_male_reproductive3.87475169
5MP0009046_muscle_twitch3.23817562
6MP0001929_abnormal_gametogenesis3.20084658
7MP0005623_abnormal_meninges_morphology3.14800157
8MP0004043_abnormal_pH_regulation2.91335037
9MP0003880_abnormal_central_pattern2.84069181
10MP0004859_abnormal_synaptic_plasticity2.81799420
11MP0008877_abnormal_DNA_methylation2.67812437
12MP0001984_abnormal_olfaction2.58611378
13MP0001986_abnormal_taste_sensitivity2.46967303
14MP0002102_abnormal_ear_morphology2.31225185
15MP0003635_abnormal_synaptic_transmissio2.30956316
16MP0005551_abnormal_eye_electrophysiolog2.23409815
17MP0002876_abnormal_thyroid_physiology2.21612337
18MP0003878_abnormal_ear_physiology2.16243248
19MP0005377_hearing/vestibular/ear_phenot2.16243248
20MP0008789_abnormal_olfactory_epithelium2.15573930
21MP0002161_abnormal_fertility/fecundity2.04323143
22MP0009745_abnormal_behavioral_response1.92113666
23MP0002064_seizures1.91586959
24MP0002210_abnormal_sex_determination1.90902205
25MP0004270_analgesia1.87846778
26MP0001486_abnormal_startle_reflex1.82389318
27MP0002734_abnormal_mechanical_nocicepti1.80896896
28MP0003136_yellow_coat_color1.78065525
29MP0001968_abnormal_touch/_nociception1.77959512
30MP0002063_abnormal_learning/memory/cond1.72787300
31MP0002572_abnormal_emotion/affect_behav1.72604277
32MP0003718_maternal_effect1.69748329
33MP0004885_abnormal_endolymph1.69064729
34MP0003011_delayed_dark_adaptation1.64781635
35MP0000383_abnormal_hair_follicle1.60967133
36MP0002272_abnormal_nervous_system1.59974698
37MP0002736_abnormal_nociception_after1.59765134
38MP0001145_abnormal_male_reproductive1.58034685
39MP0003950_abnormal_plasma_membrane1.56802983
40MP0003195_calcinosis1.55280981
41MP0001440_abnormal_grooming_behavior1.54052649
42MP0008569_lethality_at_weaning1.52479375
43MP0005423_abnormal_somatic_nervous1.52255486
44MP0002067_abnormal_sensory_capabilities1.47208441
45MP0004742_abnormal_vestibular_system1.39930764
46MP0005499_abnormal_olfactory_system1.39788843
47MP0000653_abnormal_sex_gland1.39619296
48MP0005253_abnormal_eye_physiology1.38469638
49MP0005670_abnormal_white_adipose1.37674641
50MP0000778_abnormal_nervous_system1.35136207
51MP0006072_abnormal_retinal_apoptosis1.33743148
52MP0005389_reproductive_system_phenotype1.33121939
53MP0001529_abnormal_vocalization1.32994473
54MP0003329_amyloid_beta_deposits1.32029544
55MP0002735_abnormal_chemical_nociception1.28528329
56MP0005646_abnormal_pituitary_gland1.25409095
57MP0002928_abnormal_bile_duct1.25381179
58MP0004019_abnormal_vitamin_homeostasis1.24909611
59MP0003879_abnormal_hair_cell1.24206586
60MP0001502_abnormal_circadian_rhythm1.23739432
61MP0000427_abnormal_hair_cycle1.22402591
62MP0002557_abnormal_social/conspecific_i1.21151377
63MP0003646_muscle_fatigue1.20526874
64MP0001485_abnormal_pinna_reflex1.18441426
65MP0002234_abnormal_pharynx_morphology1.18118020
66MP0000566_synostosis1.16900144
67MP0002132_abnormal_respiratory_system1.16118638
68MP0000372_irregular_coat_pigmentation1.13184711
69MP0002282_abnormal_trachea_morphology1.13060075
70MP0002184_abnormal_innervation1.12760556
71MP0002882_abnormal_neuron_morphology1.11828153
72MP0002090_abnormal_vision1.11221603
73MP0002160_abnormal_reproductive_system1.10939109
74MP0005084_abnormal_gallbladder_morpholo1.10499214
75MP0004233_abnormal_muscle_weight1.09772704
76MP0001501_abnormal_sleep_pattern1.09536067
77MP0000955_abnormal_spinal_cord1.09438739
78MP0002229_neurodegeneration1.08209045
79MP0010386_abnormal_urinary_bladder1.06134600
80MP0002138_abnormal_hepatobiliary_system1.05925882
81MP0001177_atelectasis1.05786076
82MP0000026_abnormal_inner_ear1.03984590
83MP0005395_other_phenotype1.03734796
84MP0003634_abnormal_glial_cell1.02867160
85MP0002152_abnormal_brain_morphology0.99388183
86MP0004145_abnormal_muscle_electrophysio0.96744764
87MP0001970_abnormal_pain_threshold0.95762213
88MP0010678_abnormal_skin_adnexa0.95680810
89MP0001905_abnormal_dopamine_level0.95315584
90MP0002909_abnormal_adrenal_gland0.94578239
91MP0002837_dystrophic_cardiac_calcinosis0.93755801
92MP0005636_abnormal_mineral_homeostasis0.93105921
93MP0004811_abnormal_neuron_physiology0.92419674
94MP0001324_abnormal_eye_pigmentation0.92260743
95MP0004142_abnormal_muscle_tone0.91961140
96MP0002066_abnormal_motor_capabilities/c0.90499645
97MP0003633_abnormal_nervous_system0.90286431
98MP0003122_maternal_imprinting0.87951085
99MP0002752_abnormal_somatic_nervous0.87703126
100MP0005195_abnormal_posterior_eye0.87435870
101MP0001963_abnormal_hearing_physiology0.87129498
102MP0009780_abnormal_chondrocyte_physiolo0.86974492
103MP0001346_abnormal_lacrimal_gland0.86258210
104MP0000631_abnormal_neuroendocrine_gland0.86027781
105MP0006292_abnormal_olfactory_placode0.85778128
106MP0003787_abnormal_imprinting0.85557708
107MP0002638_abnormal_pupillary_reflex0.85206918
108MP0001765_abnormal_ion_homeostasis0.85171353
109MP0001293_anophthalmia0.83343639
110MP0006276_abnormal_autonomic_nervous0.83293112
111MP0002277_abnormal_respiratory_mucosa0.80606417
112MP0005085_abnormal_gallbladder_physiolo0.79027415
113MP0002163_abnormal_gland_morphology0.78157670
114MP0002168_other_aberrant_phenotype0.77960743
115MP0005174_abnormal_tail_pigmentation0.77630538
116MP0004147_increased_porphyrin_level0.76546163
117MP0003631_nervous_system_phenotype0.76528090
118MP0004133_heterotaxia0.76331096
119MP0004782_abnormal_surfactant_physiolog0.76309994
120MP0000613_abnormal_salivary_gland0.74863952
121MP0003252_abnormal_bile_duct0.74702911
122MP0005167_abnormal_blood-brain_barrier0.74525213
123MP0008872_abnormal_physiological_respon0.74481818
124MP0002733_abnormal_thermal_nociception0.71468405
125MP0005647_abnormal_sex_gland0.71423773
126MP0005386_behavior/neurological_phenoty0.71349389
127MP0004924_abnormal_behavior0.71349389
128MP0008995_early_reproductive_senescence0.70353231
129MP0000569_abnormal_digit_pigmentation0.69881143
130MP0005388_respiratory_system_phenotype0.69199922
131MP0002133_abnormal_respiratory_system0.69199922
132MP0004858_abnormal_nervous_system0.68686459
133MP0000751_myopathy0.65242485
134MP0005595_abnormal_vascular_smooth0.64920005
135MP0005391_vision/eye_phenotype0.63958584
136MP0004036_abnormal_muscle_relaxation0.63887035
137MP0003861_abnormal_nervous_system0.62397328
138MP0005645_abnormal_hypothalamus_physiol0.60975694
139MP0005394_taste/olfaction_phenotype0.60772146

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)8.79493428
2Abnormal respiratory motile cilium morphology (HP:0005938)8.79493428
3Rhinitis (HP:0012384)7.98009182
4Chronic bronchitis (HP:0004469)6.77799324
5Bronchiectasis (HP:0002110)5.09754657
6Nasal polyposis (HP:0100582)4.78604267
7Infertility (HP:0000789)4.73596141
8Male infertility (HP:0003251)4.08381333
9Nephronophthisis (HP:0000090)4.06994168
10Abnormality of the nasal mucosa (HP:0000433)4.02194979
11Chronic hepatic failure (HP:0100626)3.84011150
12Bronchitis (HP:0012387)3.76021146
13Recurrent sinusitis (HP:0011108)3.71151534
14Abnormality of the renal medulla (HP:0100957)3.16692517
15Medial flaring of the eyebrow (HP:0010747)3.07085032
16Pancreatic fibrosis (HP:0100732)2.88661429
17Abnormality of midbrain morphology (HP:0002418)2.75104298
18Molar tooth sign on MRI (HP:0002419)2.75104298
19Recurrent otitis media (HP:0000403)2.68791771
20Absent rod-and cone-mediated responses on ERG (HP:0007688)2.61281935
21Gait imbalance (HP:0002141)2.59782556
22Abnormal rod and cone electroretinograms (HP:0008323)2.59353887
23Tubulointerstitial nephritis (HP:0001970)2.57254766
24True hermaphroditism (HP:0010459)2.57066627
25Congenital primary aphakia (HP:0007707)2.55635398
26Anencephaly (HP:0002323)2.48143555
27Male pseudohermaphroditism (HP:0000037)2.40065655
28Progressive cerebellar ataxia (HP:0002073)2.36966045
29Tubular atrophy (HP:0000092)2.36751764
30Aplasia/Hypoplasia of the spleen (HP:0010451)2.32119414
31Chronic sinusitis (HP:0011109)2.29856049
32Congenital hepatic fibrosis (HP:0002612)2.24714852
33Postaxial foot polydactyly (HP:0001830)2.24502953
34Nephrogenic diabetes insipidus (HP:0009806)2.23618656
35Asplenia (HP:0001746)2.21805335
36Tubulointerstitial abnormality (HP:0001969)2.21345161
37Chronic otitis media (HP:0000389)2.18038766
38Type II lissencephaly (HP:0007260)2.16539102
39Decreased circulating renin level (HP:0003351)2.15074907
40Epileptic encephalopathy (HP:0200134)2.09820791
41Furrowed tongue (HP:0000221)2.06477602
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.04705064
43Bile duct proliferation (HP:0001408)2.03426017
44Abnormal biliary tract physiology (HP:0012439)2.03426017
45Attenuation of retinal blood vessels (HP:0007843)2.01326426
46Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.9060067
47Abnormal respiratory motile cilium physiology (HP:0012261)10.6168433
48Absent/shortened dynein arms (HP:0200106)10.4755113
49Dynein arm defect of respiratory motile cilia (HP:0012255)10.4755113
50Abnormal ciliary motility (HP:0012262)10.2593683
51Stage 5 chronic kidney disease (HP:0003774)1.99267295
52Tubulointerstitial fibrosis (HP:0005576)1.99143385
53Cystic liver disease (HP:0006706)1.97916278
54Bony spicule pigmentary retinopathy (HP:0007737)1.97174167
55Median cleft lip (HP:0000161)1.97168211
56Genital tract atresia (HP:0001827)1.94088492
57Pancreatic cysts (HP:0001737)1.89690225
58Hyperactive renin-angiotensin system (HP:0000841)1.87976502
59Vaginal atresia (HP:0000148)1.82422894
60Postaxial hand polydactyly (HP:0001162)1.81266183
61Abnormality of the lower motor neuron (HP:0002366)1.80345531
62Decreased central vision (HP:0007663)1.80339613
63Poor coordination (HP:0002370)1.79026830
64Abnormality of cochlea (HP:0000375)1.76757522
65Genetic anticipation (HP:0003743)1.76534650
66Polyuria (HP:0000103)1.75587420
67Recurrent bronchitis (HP:0002837)1.74835694
68Hyperkalemia (HP:0002153)1.74324495
69Aplasia/Hypoplasia of the lens (HP:0008063)1.74264360
70Abolished electroretinogram (ERG) (HP:0000550)1.71059103
71Occipital encephalocele (HP:0002085)1.70815922
72Abnormality of dentin (HP:0010299)1.70488178
73Fibular hypoplasia (HP:0003038)1.69499462
74Congenital stationary night blindness (HP:0007642)1.67876567
75Hemiparesis (HP:0001269)1.67215043
76Abnormal spermatogenesis (HP:0008669)1.66443593
77Retinitis pigmentosa (HP:0000510)1.63855805
78Abnormality of permanent molar morphology (HP:0011071)1.63317614
79Abnormality of the dental root (HP:0006486)1.63317614
80Taurodontia (HP:0000679)1.63317614
81Abnormal drinking behavior (HP:0030082)1.63277656
82Polydipsia (HP:0001959)1.63277656
83Oculomotor apraxia (HP:0000657)1.62280768
84Gaze-evoked nystagmus (HP:0000640)1.61256977
85Cerebellar dysplasia (HP:0007033)1.60324686
86Focal motor seizures (HP:0011153)1.59559724
87Cone-rod dystrophy (HP:0000548)1.56838272
88Supernumerary spleens (HP:0009799)1.56244582
89Abnormal gallbladder physiology (HP:0012438)1.53682293
90Cholecystitis (HP:0001082)1.53682293
91Pendular nystagmus (HP:0012043)1.52938118
92Abnormality of the renal cortex (HP:0011035)1.51096798
93Abnormality of molar morphology (HP:0011070)1.50607673
94Abnormality of molar (HP:0011077)1.50607673
95Atelectasis (HP:0100750)1.49336119
96Keratoconus (HP:0000563)1.47726813
97Increased corneal curvature (HP:0100692)1.47726813
98Abnormality of the dental pulp (HP:0006479)1.47009352
99Abnormality of macular pigmentation (HP:0008002)1.46111682
100Renal salt wasting (HP:0000127)1.45895287
101Abnormality of ocular smooth pursuit (HP:0000617)1.45420850
102Myokymia (HP:0002411)1.43164289
103Abnormal urine output (HP:0012590)1.42987913
104Narrow forehead (HP:0000341)1.42773418
105Short ribs (HP:0000773)1.41788334
106Neurofibrillary tangles (HP:0002185)1.41196541
107Abnormality of chloride homeostasis (HP:0011422)1.40905374
108Abnormality of renin-angiotensin system (HP:0000847)1.39646159
109Preaxial hand polydactyly (HP:0001177)1.39635798
110Microglossia (HP:0000171)1.38107841
111Aganglionic megacolon (HP:0002251)1.37950610
112Specific learning disability (HP:0001328)1.37756713
113Bell-shaped thorax (HP:0001591)1.36678652
114Exercise-induced myalgia (HP:0003738)1.36585460
115Hyperaldosteronism (HP:0000859)1.35720044
116Retinal dysplasia (HP:0007973)1.35516762
117Central scotoma (HP:0000603)1.34960781
118Abdominal situs inversus (HP:0003363)1.34675570
119Abnormality of abdominal situs (HP:0011620)1.34675570
120Absent speech (HP:0001344)1.34282918
121Sclerocornea (HP:0000647)1.33959785
122Widely spaced teeth (HP:0000687)1.33332718
123Focal seizures (HP:0007359)1.32910150
124Megalencephaly (HP:0001355)1.32607358
125Prominent nasal bridge (HP:0000426)1.32606700
126Nephropathy (HP:0000112)1.32475956
127Severe visual impairment (HP:0001141)1.31423039
128Facial cleft (HP:0002006)1.31350613
129Multicystic kidney dysplasia (HP:0000003)1.31091731
130Morphological abnormality of the inner ear (HP:0011390)1.30597785
131Azoospermia (HP:0000027)1.29445990
132Macular degeneration (HP:0000608)1.29007390
133Renal dysplasia (HP:0000110)1.28869862
134Broad-based gait (HP:0002136)1.26869156
135Aplasia/hypoplasia of the uterus (HP:0008684)1.25486419
136Dysdiadochokinesis (HP:0002075)1.24193426
137Disproportionate short-trunk short stature (HP:0003521)1.24086434
138Abnormality of renal excretion (HP:0011036)1.23754923
139J-shaped sella turcica (HP:0002680)1.22191982

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.04573873
2PDK36.04573873
3LMTK25.14051939
4PDK24.05572571
5FRK3.79115616
6PNCK3.47233375
7PRKD33.06293782
8MAP4K22.88937655
9MST42.85393331
10TESK12.77535603
11MAPK152.69396440
12ADRBK22.65846288
13TLK12.64790609
14ZAK2.62565186
15BMPR1B2.32801507
16PTK2B2.27861029
17STK162.23128974
18WNK42.07593101
19STK392.07563363
20ICK2.05105746
21TAOK32.03498724
22NTRK21.82300289
23EPHA41.72943306
24INSRR1.63802652
25NTRK31.61754783
26BCR1.59951768
27DAPK21.58094962
28MAP2K71.56178845
29MARK11.52992201
30MAP3K41.45916437
31STK381.43098806
32MAPKAPK31.43050632
33CASK1.40619005
34NUAK11.35747881
35ACVR1B1.32098140
36PLK41.26640449
37WNK11.22658789
38NME11.21478908
39PINK11.14375991
40MINK11.11196585
41CAMK1G1.10859569
42SIK21.07361052
43BRSK21.04670793
44STK38L1.01142569
45PRKG20.96995853
46TYRO30.96514046
47TXK0.95980587
48PHKG10.94044806
49PHKG20.94044806
50PRKCI0.92120737
51PRKCG0.91231026
52EPHA20.88529187
53PDK10.87040803
54SIK30.85238663
55TSSK60.85177653
56MAP3K90.83248658
57TRIM280.82491304
58ADRBK10.80968601
59MARK20.80425116
60DYRK20.79592934
61STK240.78789336
62CAMKK10.78711631
63PLK20.78455112
64PRPF4B0.78201488
65GRK10.77689736
66CSNK1G20.76076892
67GRK50.75902532
68MKNK20.75272782
69PAK30.74740939
70NEK60.73884930
71DYRK1A0.72322921
72OXSR10.71771262
73IRAK10.71622299
74MUSK0.71463829
75SGK2230.69356564
76SGK4940.69356564
77CDK50.67373885
78PAK60.64365437
79TTK0.61153860
80VRK10.61130825
81CSNK1G10.59715295
82PRKAA10.59627444
83MAPK130.59174769
84CAMK2A0.58419992
85SIK10.58184178
86CSNK1G30.57987353
87BCKDK0.56958841
88DYRK1B0.55135382
89PLK10.55040890
90CCNB10.54783546
91FES0.52942975
92CSNK1A1L0.52688087
93PDPK10.52428417
94TGFBR10.51869531
95SGK20.51636897
96FGR0.51473221
97PRKG10.51020210
98PKN10.49655035
99PRKCH0.49178117
100IRAK20.48620008
101TNIK0.48390940
102PRKCE0.45874546
103CDK30.45809799
104KIT0.45684962
105ROCK20.45607913
106CDK150.44695154
107FGFR20.44646826
108CDK180.43905149
109MAP2K40.43327439
110PLK30.43276872
111CDK190.43155637
112TEC0.42533061
113EIF2AK30.42041051
114WEE10.41479237
115WNK30.41355394
116CDK140.41059042
117CDC42BPA0.40039574
118MAP2K60.38699927
119ROCK10.38489346
120MAP3K70.37897385
121CAMK10.37583904
122CDK11A0.37493482
123STK110.36635899
124MAPK100.34744217
125CSNK1A10.34661817
126RIPK40.34214950
127STK30.34165226
128DYRK30.34061034
129MET0.32607402
130CHUK0.31920056
131RPS6KA30.31447276
132DAPK10.31427189
133TIE10.31309355
134TRPM70.30246965
135SGK10.29536417
136ABL10.29099213
137IGF1R0.29036600
138CAMK2D0.28655504
139SGK30.28525461
140CAMKK20.28379114
141PRKCZ0.27880585
142ERBB20.27785392
143PIK3CA0.27739473
144FER0.24625323
145PRKCB0.24333351
146PRKCA0.24243500
147ERBB30.23983154
148MAPKAPK50.23715262
149CAMK2B0.23253228
150RPS6KA20.21285908
151PRKACA0.20414268
152GSK3B0.19546355
153CHEK20.19497065
154PRKCQ0.19359656
155UHMK10.18460018

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.37727414
2Synaptic vesicle cycle_Homo sapiens_hsa047213.01108206
3Caffeine metabolism_Homo sapiens_hsa002322.90416122
4Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.53842088
5GABAergic synapse_Homo sapiens_hsa047272.52445012
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.51040427
7Chemical carcinogenesis_Homo sapiens_hsa052042.50937198
8Morphine addiction_Homo sapiens_hsa050322.40635917
9Circadian entrainment_Homo sapiens_hsa047132.35693701
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.32877988
11Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.32556525
12Olfactory transduction_Homo sapiens_hsa047402.31715363
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.30915735
14Taste transduction_Homo sapiens_hsa047422.26077226
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.24871617
16Renin secretion_Homo sapiens_hsa049242.24813005
17Nitrogen metabolism_Homo sapiens_hsa009102.08858729
18Insulin secretion_Homo sapiens_hsa049112.08588450
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.08336639
20Collecting duct acid secretion_Homo sapiens_hsa049662.07844781
21Salivary secretion_Homo sapiens_hsa049702.06459118
22Amphetamine addiction_Homo sapiens_hsa050312.05247136
23Glutamatergic synapse_Homo sapiens_hsa047242.03026250
24Vitamin B6 metabolism_Homo sapiens_hsa007501.98505909
25Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.87374305
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.82895016
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.80377164
28Long-term potentiation_Homo sapiens_hsa047201.75206644
29Butanoate metabolism_Homo sapiens_hsa006501.75125143
30Histidine metabolism_Homo sapiens_hsa003401.72935758
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.71713760
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.69245657
33Dorso-ventral axis formation_Homo sapiens_hsa043201.68416853
34Gastric acid secretion_Homo sapiens_hsa049711.65678760
35Retinol metabolism_Homo sapiens_hsa008301.64089960
36ABC transporters_Homo sapiens_hsa020101.62128879
37Fatty acid biosynthesis_Homo sapiens_hsa000611.59840719
38beta-Alanine metabolism_Homo sapiens_hsa004101.58388461
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.56811917
40Calcium signaling pathway_Homo sapiens_hsa040201.53755390
41Dopaminergic synapse_Homo sapiens_hsa047281.49952791
42Glucagon signaling pathway_Homo sapiens_hsa049221.48710080
43Tryptophan metabolism_Homo sapiens_hsa003801.46288883
44Basal transcription factors_Homo sapiens_hsa030221.43144752
45Phenylalanine metabolism_Homo sapiens_hsa003601.38403755
46Intestinal immune network for IgA production_Homo sapiens_hsa046721.37610774
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.35260515
48Tyrosine metabolism_Homo sapiens_hsa003501.34615759
49Peroxisome_Homo sapiens_hsa041461.34558279
50Carbohydrate digestion and absorption_Homo sapiens_hsa049731.32515875
51Cholinergic synapse_Homo sapiens_hsa047251.32470025
52Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.32204710
53Aldosterone synthesis and secretion_Homo sapiens_hsa049251.31406970
54Steroid hormone biosynthesis_Homo sapiens_hsa001401.31214135
55Oxidative phosphorylation_Homo sapiens_hsa001901.30279144
56Primary bile acid biosynthesis_Homo sapiens_hsa001201.29370129
57Mineral absorption_Homo sapiens_hsa049781.29357821
58cGMP-PKG signaling pathway_Homo sapiens_hsa040221.28879453
59Oxytocin signaling pathway_Homo sapiens_hsa049211.24529585
60RNA polymerase_Homo sapiens_hsa030201.23397797
61Cardiac muscle contraction_Homo sapiens_hsa042601.22001021
62Circadian rhythm_Homo sapiens_hsa047101.21529021
63Vibrio cholerae infection_Homo sapiens_hsa051101.20400311
64Regulation of autophagy_Homo sapiens_hsa041401.19863593
65Arachidonic acid metabolism_Homo sapiens_hsa005901.19858980
66cAMP signaling pathway_Homo sapiens_hsa040241.19740418
67Cocaine addiction_Homo sapiens_hsa050301.19287763
68Pyruvate metabolism_Homo sapiens_hsa006201.18860210
69Long-term depression_Homo sapiens_hsa047301.16231334
70Selenocompound metabolism_Homo sapiens_hsa004501.13602092
71Asthma_Homo sapiens_hsa053101.11727532
72Estrogen signaling pathway_Homo sapiens_hsa049151.09477709
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.08289981
74Pancreatic secretion_Homo sapiens_hsa049721.07959446
75Oocyte meiosis_Homo sapiens_hsa041141.07575461
76Phototransduction_Homo sapiens_hsa047441.07415855
77Glycerophospholipid metabolism_Homo sapiens_hsa005641.05482049
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.04367986
79Serotonergic synapse_Homo sapiens_hsa047261.03322076
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.01801894
81Type I diabetes mellitus_Homo sapiens_hsa049401.00256554
82Huntingtons disease_Homo sapiens_hsa050161.00189048
83Phosphatidylinositol signaling system_Homo sapiens_hsa040701.00103564
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97544002
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.97460804
86Fatty acid degradation_Homo sapiens_hsa000710.95874339
87Allograft rejection_Homo sapiens_hsa053300.93428936
88Glutathione metabolism_Homo sapiens_hsa004800.93275978
89Protein export_Homo sapiens_hsa030600.92814477
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.91930703
91Axon guidance_Homo sapiens_hsa043600.85058781
92Thyroid hormone synthesis_Homo sapiens_hsa049180.85040101
93RNA degradation_Homo sapiens_hsa030180.84850774
94Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.83997414
95Type II diabetes mellitus_Homo sapiens_hsa049300.83033558
96Autoimmune thyroid disease_Homo sapiens_hsa053200.82749018
97Gap junction_Homo sapiens_hsa045400.78813735
98Ether lipid metabolism_Homo sapiens_hsa005650.78573593
99Parkinsons disease_Homo sapiens_hsa050120.77616686
100Glycerolipid metabolism_Homo sapiens_hsa005610.77503285
101Graft-versus-host disease_Homo sapiens_hsa053320.75264707
102Bile secretion_Homo sapiens_hsa049760.74229114
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.73673695
104Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71682570
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70049039
106Ovarian steroidogenesis_Homo sapiens_hsa049130.68619686
107Homologous recombination_Homo sapiens_hsa034400.66908901
108Melanogenesis_Homo sapiens_hsa049160.66618573
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65912918
110Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65673831
111Metabolic pathways_Homo sapiens_hsa011000.63484084
112Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.62749670
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62615073
114Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62091433
115Propanoate metabolism_Homo sapiens_hsa006400.61654530
116GnRH signaling pathway_Homo sapiens_hsa049120.60275392
117Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58540349
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57534846
119Linoleic acid metabolism_Homo sapiens_hsa005910.57470712
120Inositol phosphate metabolism_Homo sapiens_hsa005620.55403659
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55092720
122Wnt signaling pathway_Homo sapiens_hsa043100.53042035
123Fructose and mannose metabolism_Homo sapiens_hsa000510.52310926
124Sphingolipid metabolism_Homo sapiens_hsa006000.52178126
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51606504
126Alcoholism_Homo sapiens_hsa050340.48901128
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47810206
128Dilated cardiomyopathy_Homo sapiens_hsa054140.47126035
129Rheumatoid arthritis_Homo sapiens_hsa053230.47100995
130Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46983141
131Endocytosis_Homo sapiens_hsa041440.46740070
132MAPK signaling pathway_Homo sapiens_hsa040100.46266532
133Alzheimers disease_Homo sapiens_hsa050100.45763832
134Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45167112
135AMPK signaling pathway_Homo sapiens_hsa041520.44559698
136Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.44387019
137Steroid biosynthesis_Homo sapiens_hsa001000.43891094
138Hedgehog signaling pathway_Homo sapiens_hsa043400.43784361
139Fat digestion and absorption_Homo sapiens_hsa049750.42878860
140Tight junction_Homo sapiens_hsa045300.41337397
141Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40584390
142Pentose phosphate pathway_Homo sapiens_hsa000300.40051482
143Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39597848
144SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39025664
145Glycosaminoglycan degradation_Homo sapiens_hsa005310.38063024
146Phospholipase D signaling pathway_Homo sapiens_hsa040720.37485016
147Fanconi anemia pathway_Homo sapiens_hsa034600.37285497
148Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35859729
149Central carbon metabolism in cancer_Homo sapiens_hsa052300.35713762
150Drug metabolism - other enzymes_Homo sapiens_hsa009830.35171066
151PPAR signaling pathway_Homo sapiens_hsa033200.35081135
152Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.34555057
153Choline metabolism in cancer_Homo sapiens_hsa052310.34115345
154Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33865713
155Phagosome_Homo sapiens_hsa041450.33046505
156Purine metabolism_Homo sapiens_hsa002300.32940342
157Primary immunodeficiency_Homo sapiens_hsa053400.32763277
158One carbon pool by folate_Homo sapiens_hsa006700.30532548
159Arginine and proline metabolism_Homo sapiens_hsa003300.29772704

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