RSPH14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.80717136
2sensory perception of smell (GO:0007608)9.59151018
3epithelial cilium movement (GO:0003351)9.37407559
4protein localization to cilium (GO:0061512)9.32545475
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.88031108
6regulation of cilium movement (GO:0003352)8.30826282
7motile cilium assembly (GO:0044458)8.25654198
8regulation of chromatin binding (GO:0035561)6.25984965
9sensory perception of chemical stimulus (GO:0007606)5.95132283
10sperm motility (GO:0030317)5.87528475
11intraciliary transport (GO:0042073)5.77426292
12protein polyglutamylation (GO:0018095)5.75883654
13GTP biosynthetic process (GO:0006183)5.73593097
14acrosome reaction (GO:0007340)5.50501237
15ventricular system development (GO:0021591)5.41044634
16adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.39497287
17microtubule bundle formation (GO:0001578)5.22946234
18nucleoside diphosphate phosphorylation (GO:0006165)5.22764755
19cilium morphogenesis (GO:0060271)5.16055117
20cilium assembly (GO:0042384)5.11836194
21cilium organization (GO:0044782)5.07193975
22microtubule severing (GO:0051013)4.99478836
23regulation of microtubule-based movement (GO:0060632)4.97477751
24UTP biosynthetic process (GO:0006228)4.90552147
25female mating behavior (GO:0060180)4.88222964
26left/right axis specification (GO:0070986)4.79072692
27regulation of female receptivity (GO:0045924)4.45970486
28guanosine-containing compound biosynthetic process (GO:1901070)4.45470912
29fusion of sperm to egg plasma membrane (GO:0007342)4.38337026
30sperm-egg recognition (GO:0035036)4.32524584
31cellular component assembly involved in morphogenesis (GO:0010927)4.31143589
32UTP metabolic process (GO:0046051)4.28422668
33acrosome assembly (GO:0001675)4.20429506
34multicellular organism reproduction (GO:0032504)4.15613873
35cellular ketone body metabolic process (GO:0046950)4.09873806
36spermatid development (GO:0007286)4.07214413
37binding of sperm to zona pellucida (GO:0007339)4.05894347
38centriole assembly (GO:0098534)3.99948471
39CTP metabolic process (GO:0046036)3.96925710
40CTP biosynthetic process (GO:0006241)3.96925710
41cell-cell recognition (GO:0009988)3.83809629
42response to pheromone (GO:0019236)3.78601508
43left/right pattern formation (GO:0060972)3.77795712
44single fertilization (GO:0007338)3.76112270
45one-carbon compound transport (GO:0019755)3.74180213
46microtubule-based movement (GO:0007018)3.70536762
47detection of calcium ion (GO:0005513)3.63658504
48cell wall macromolecule metabolic process (GO:0044036)3.63342160
49cell wall macromolecule catabolic process (GO:0016998)3.63342160
50nonmotile primary cilium assembly (GO:0035058)3.60394967
51microtubule depolymerization (GO:0007019)3.59184750
52ketone body metabolic process (GO:1902224)3.58161060
53centriole replication (GO:0007099)3.53554145
54plasma membrane fusion (GO:0045026)3.52499773
55calcium ion-dependent exocytosis (GO:0017156)3.50852325
56pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.47806840
57sperm capacitation (GO:0048240)3.44473725
58protein neddylation (GO:0045116)3.36401803
59male meiosis (GO:0007140)3.34687436
60negative regulation of inclusion body assembly (GO:0090084)3.33481423
61negative regulation of heart rate (GO:0010459)3.32077576
62positive regulation of meiosis (GO:0045836)3.27732568
63retinal cone cell development (GO:0046549)3.27098238
64reproduction (GO:0000003)3.25064926
65cell projection assembly (GO:0030031)3.23300966
66pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.19371662
67fertilization (GO:0009566)3.17346178
68piRNA metabolic process (GO:0034587)3.17071067
69calcium-mediated signaling using intracellular calcium source (GO:0035584)3.15139662
70synaptic vesicle docking involved in exocytosis (GO:0016081)3.13520411
71pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.10131312
72auditory receptor cell differentiation (GO:0042491)3.09072128
73lactate metabolic process (GO:0006089)3.08431621
74positive regulation of meiotic cell cycle (GO:0051446)3.02536891
75spermatid nucleus differentiation (GO:0007289)3.02333739
76behavioral response to nicotine (GO:0035095)3.01575445
77nucleotide phosphorylation (GO:0046939)2.99753333
78synaptonemal complex organization (GO:0070193)2.91430745
79sex differentiation (GO:0007548)2.90917197
80inner ear receptor cell development (GO:0060119)2.90446153
81microtubule polymerization or depolymerization (GO:0031109)2.90389628
82negative regulation of transcription regulatory region DNA binding (GO:2000678)2.86533403
83male meiosis I (GO:0007141)2.86261120
84smoothened signaling pathway (GO:0007224)2.85106658
85transmission of nerve impulse (GO:0019226)2.83729339
86melanosome transport (GO:0032402)2.82830601
87behavioral response to cocaine (GO:0048148)2.82149214
88spermatogenesis (GO:0007283)2.82036071
89brain morphogenesis (GO:0048854)2.80535887
90male gamete generation (GO:0048232)2.79961303
91regulation of meiosis I (GO:0060631)2.79678197
92adipose tissue development (GO:0060612)2.77947508
93peptidyl-glutamic acid modification (GO:0018200)2.77742787
94pigment granule transport (GO:0051904)2.76973418
95glycerophospholipid catabolic process (GO:0046475)2.76652413
96pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.75107538
97preassembly of GPI anchor in ER membrane (GO:0016254)2.73822845
98olfactory bulb development (GO:0021772)2.71888253
99negative regulation of cytosolic calcium ion concentration (GO:0051481)2.71729194
100cornea development in camera-type eye (GO:0061303)2.71719533
101establishment of melanosome localization (GO:0032401)2.71670589
102regulation of protein kinase A signaling (GO:0010738)2.71355333
103positive regulation of glycolytic process (GO:0045821)2.71149059
104pyrimidine nucleobase catabolic process (GO:0006208)2.71026254
105establishment of pigment granule localization (GO:0051905)2.66586915
106cell recognition (GO:0008037)2.63412874
107neural tube formation (GO:0001841)2.61603754
108organic cation transport (GO:0015695)2.60938597
109gamete generation (GO:0007276)2.57989380
110nucleoside diphosphate metabolic process (GO:0009132)2.57731491
111photoreceptor cell maintenance (GO:0045494)2.57261189
112water-soluble vitamin biosynthetic process (GO:0042364)2.56727498
113nucleobase catabolic process (GO:0046113)2.55407227
114detection of light stimulus involved in visual perception (GO:0050908)2.54754582
115detection of light stimulus involved in sensory perception (GO:0050962)2.54754582
116dopamine receptor signaling pathway (GO:0007212)2.54592541
117exogenous drug catabolic process (GO:0042738)2.53079180
118presynaptic membrane assembly (GO:0097105)2.53032622
119negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.51482626
120neuronal action potential propagation (GO:0019227)2.48844401
121response to monoamine (GO:0071867)2.46250077
122response to catecholamine (GO:0071869)2.46250077
123regulation of glucokinase activity (GO:0033131)2.46169241
124regulation of hexokinase activity (GO:1903299)2.46169241
125melanosome localization (GO:0032400)2.46073865
126inner ear receptor cell differentiation (GO:0060113)2.45251697
127neurotransmitter metabolic process (GO:0042133)2.44328695
128meiotic chromosome segregation (GO:0045132)2.43178993
129pigment granule localization (GO:0051875)2.42480361
130positive regulation of synaptic transmission, GABAergic (GO:0032230)2.39721210
131presynaptic membrane organization (GO:0097090)2.39164917
132GPI anchor metabolic process (GO:0006505)2.37200603
133nitric oxide mediated signal transduction (GO:0007263)2.36581235
134adenosine metabolic process (GO:0046085)2.36498248
135platelet dense granule organization (GO:0060155)2.36168190
136cochlea development (GO:0090102)2.35499474
137xenobiotic catabolic process (GO:0042178)2.35324071
138polyol catabolic process (GO:0046174)2.32499941
139negative regulation of response to food (GO:0032096)2.31776001
140negative regulation of appetite (GO:0032099)2.31776001
141DNA methylation involved in gamete generation (GO:0043046)2.29325390
142determination of left/right symmetry (GO:0007368)2.28308545
143L-phenylalanine catabolic process (GO:0006559)2.26681642
144erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.26681642
145regulation of neurotransmitter uptake (GO:0051580)2.26233274
146gamma-aminobutyric acid transport (GO:0015812)2.25174310
147phosphatidylethanolamine biosynthetic process (GO:0006646)2.24288871
148L-fucose catabolic process (GO:0042355)2.23953483
149fucose catabolic process (GO:0019317)2.23953483
150L-fucose metabolic process (GO:0042354)2.23953483
151calcium ion import (GO:0070509)2.23619200
152phosphatidylethanolamine metabolic process (GO:0046337)2.23262768
153positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.23032799
154neurotransmitter biosynthetic process (GO:0042136)2.22579969
155neurotransmitter catabolic process (GO:0042135)2.21900188
156pyrimidine-containing compound transmembrane transport (GO:0072531)2.21698706
157cilium movement (GO:0003341)11.3137439
158axonemal dynein complex assembly (GO:0070286)10.5843592
159axoneme assembly (GO:0035082)10.0160064

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human8.74099786
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.01655188
3TAF15_26573619_Chip-Seq_HEK293_Human2.98680776
4RBPJ_22232070_ChIP-Seq_NCS_Mouse2.81143139
5GBX2_23144817_ChIP-Seq_PC3_Human2.80260883
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.79008429
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.70886129
8ZNF274_21170338_ChIP-Seq_K562_Hela2.53674977
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.30818123
10IGF1R_20145208_ChIP-Seq_DFB_Human2.19933726
11VDR_22108803_ChIP-Seq_LS180_Human2.01209104
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.00004142
13FUS_26573619_Chip-Seq_HEK293_Human1.88361002
14CBX2_27304074_Chip-Seq_ESCs_Mouse1.88325611
15DROSHA_22980978_ChIP-Seq_HELA_Human1.88318862
16RNF2_27304074_Chip-Seq_NSC_Mouse1.81355312
17ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79412851
18AR_25329375_ChIP-Seq_VCAP_Human1.75370032
19EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73286338
20REST_21632747_ChIP-Seq_MESCs_Mouse1.69110868
21EWS_26573619_Chip-Seq_HEK293_Human1.64976180
22SUZ12_27294783_Chip-Seq_ESCs_Mouse1.63958192
23CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63551246
24AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.63479590
25GATA1_26923725_Chip-Seq_HPCs_Mouse1.61535341
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60961331
27SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.59566372
28EZH2_27304074_Chip-Seq_ESCs_Mouse1.58111560
29POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.56921303
30TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56921303
31P300_19829295_ChIP-Seq_ESCs_Human1.56332137
32EZH2_18974828_ChIP-Seq_MESCs_Mouse1.54727753
33RNF2_18974828_ChIP-Seq_MESCs_Mouse1.54727753
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52481545
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.52192792
36JARID2_20064375_ChIP-Seq_MESCs_Mouse1.51204723
37SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.51168713
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.50704041
39SMAD4_21799915_ChIP-Seq_A2780_Human1.46323986
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.44035799
41SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43980988
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.43523318
43SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.43329696
44CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42662038
45JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40144523
46SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.39879107
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39426560
48IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38842549
49CBP_20019798_ChIP-Seq_JUKART_Human1.38842549
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37536383
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.37175502
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36688757
53MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36029897
54SOX2_19829295_ChIP-Seq_ESCs_Human1.35672446
55NANOG_19829295_ChIP-Seq_ESCs_Human1.35672446
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35485324
57NR3C1_21868756_ChIP-Seq_MCF10A_Human1.34323066
58TAL1_26923725_Chip-Seq_HPCs_Mouse1.33086074
59E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.31310402
60SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.30490941
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.27265244
62MTF2_20144788_ChIP-Seq_MESCs_Mouse1.26973782
63TCF4_22108803_ChIP-Seq_LS180_Human1.25878166
64ER_23166858_ChIP-Seq_MCF-7_Human1.25682529
65PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25050881
66LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24263607
67SMAD4_21741376_ChIP-Seq_EPCs_Human1.24100199
68GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22839189
69EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.22835724
70HTT_18923047_ChIP-ChIP_STHdh_Human1.20854073
71TBL1_22424771_ChIP-Seq_293T_Human1.20165072
72EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.20142737
73SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.18634945
74CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18236673
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17665625
76IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17270833
77RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.17042609
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.16770601
79FOXA1_25329375_ChIP-Seq_VCAP_Human1.16715663
80FOXA1_27270436_Chip-Seq_PROSTATE_Human1.16715663
81PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16095328
82PHF8_20622853_ChIP-Seq_HELA_Human1.15735948
83TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15313674
84PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.14992636
85CDX2_22108803_ChIP-Seq_LS180_Human1.14493631
86TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14101909
87ELK4_26923725_Chip-Seq_MESODERM_Mouse1.13385141
88NCOR_22424771_ChIP-Seq_293T_Human1.12465267
89SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12427023
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11684948
91TP53_22573176_ChIP-Seq_HFKS_Human1.11034794
92CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.10995744
93P53_22387025_ChIP-Seq_ESCs_Mouse1.10368895
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10193066
95AHR_22903824_ChIP-Seq_MCF-7_Human1.10191552
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10124181
97BCAT_22108803_ChIP-Seq_LS180_Human1.09991456
98RBPJ_21746931_ChIP-Seq_IB4_Human1.09865631
99POU3F2_20337985_ChIP-ChIP_501MEL_Human1.09840490
100NFYB_21822215_ChIP-Seq_K562_Human1.08986148
101CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08524950
102TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07739312
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07542256
104PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.07191578
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.07137057
106CBX2_22325352_ChIP-Seq_293T-Rex_Human1.07027345
107SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.06463819
108SOX2_21211035_ChIP-Seq_LN229_Gbm1.06409866
109STAT1_17558387_ChIP-Seq_HELA_Human1.06366255
110KDM2B_26808549_Chip-Seq_REH_Human1.06094311
111PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05666350
112NFYA_21822215_ChIP-Seq_K562_Human1.05387739
113AR_20517297_ChIP-Seq_VCAP_Human1.05092408
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.03996558
115HNFA_21074721_ChIP-Seq_CACO-2_Human1.03741137
116NFE2_27457419_Chip-Seq_LIVER_Mouse1.03618284
117NANOG_18555785_Chip-Seq_ESCs_Mouse1.03276545
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03250286
119RUNX2_22187159_ChIP-Seq_PCA_Human1.02313379
120MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.02043976
121FOXA1_21572438_ChIP-Seq_LNCaP_Human1.00436312
122SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00250105
123JUN_21703547_ChIP-Seq_K562_Human1.00071348
124GF1_26923725_Chip-Seq_HPCs_Mouse0.99373323
125TCF4_23295773_ChIP-Seq_U87_Human0.99087138
126SOX2_18555785_Chip-Seq_ESCs_Mouse0.98928846
127ARNT_22903824_ChIP-Seq_MCF-7_Human0.97954202
128EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97234314
129RING1B_27294783_Chip-Seq_ESCs_Mouse0.97126870
130OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96635544
131PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.96179850
132WDR5_24793694_ChIP-Seq_LNCAP_Human0.95977036
133FLI1_21867929_ChIP-Seq_TH2_Mouse0.95810665
134SOX2_22085726_ChIP-Seq_NPCs_Mouse0.95773915
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.95271533
136CMYC_18555785_Chip-Seq_ESCs_Mouse0.94749624
137REST_18959480_ChIP-ChIP_MESCs_Mouse0.94288405
138ETV1_20927104_ChIP-Seq_GIST48_Human0.94171786
139E2F1_18555785_Chip-Seq_ESCs_Mouse0.93477260
140STAT3_23295773_ChIP-Seq_U87_Human0.93129080

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction8.57653457
2MP0005410_abnormal_fertilization5.34474094
3MP0005645_abnormal_hypothalamus_physiol4.38283229
4MP0008789_abnormal_olfactory_epithelium4.17002308
5MP0005394_taste/olfaction_phenotype3.72406599
6MP0005499_abnormal_olfactory_system3.72406599
7MP0002653_abnormal_ependyma_morphology2.65130565
8MP0002160_abnormal_reproductive_system2.64761296
9MP0005623_abnormal_meninges_morphology2.56362224
10MP0002837_dystrophic_cardiac_calcinosis2.27579932
11MP0000372_irregular_coat_pigmentation2.26034968
12MP0009780_abnormal_chondrocyte_physiolo2.21080206
13MP0008877_abnormal_DNA_methylation2.20069949
14MP0003698_abnormal_male_reproductive2.15655174
15MP0003880_abnormal_central_pattern2.11350134
16MP0002184_abnormal_innervation2.06200296
17MP0003195_calcinosis1.91906928
18MP0005646_abnormal_pituitary_gland1.88378601
19MP0002734_abnormal_mechanical_nocicepti1.84790093
20MP0002272_abnormal_nervous_system1.81858123
21MP0005174_abnormal_tail_pigmentation1.80955865
22MP0004270_analgesia1.76291656
23MP0006276_abnormal_autonomic_nervous1.65991427
24MP0002557_abnormal_social/conspecific_i1.65248244
25MP0000778_abnormal_nervous_system1.64959317
26MP0004133_heterotaxia1.62948621
27MP0003635_abnormal_synaptic_transmissio1.59304891
28MP0001929_abnormal_gametogenesis1.57369016
29MP0005377_hearing/vestibular/ear_phenot1.56253165
30MP0003878_abnormal_ear_physiology1.56253165
31MP0009046_muscle_twitch1.55219884
32MP0005379_endocrine/exocrine_gland_phen1.54311860
33MP0002063_abnormal_learning/memory/cond1.48508043
34MP0002938_white_spotting1.47407669
35MP0008995_early_reproductive_senescence1.45910005
36MP0002877_abnormal_melanocyte_morpholog1.44852219
37MP0004885_abnormal_endolymph1.44626771
38MP0005551_abnormal_eye_electrophysiolog1.43302115
39MP0008872_abnormal_physiological_respon1.41752988
40MP0005389_reproductive_system_phenotype1.39282615
41MP0005464_abnormal_platelet_physiology1.38943393
42MP0001486_abnormal_startle_reflex1.38791700
43MP0004782_abnormal_surfactant_physiolog1.38679198
44MP0003121_genomic_imprinting1.38650020
45MP0001188_hyperpigmentation1.38595991
46MP0002210_abnormal_sex_determination1.38429680
47MP0009745_abnormal_behavioral_response1.38227320
48MP0001968_abnormal_touch/_nociception1.36271713
49MP0002572_abnormal_emotion/affect_behav1.35034836
50MP0002822_catalepsy1.33480951
51MP0000566_synostosis1.33272952
52MP0001485_abnormal_pinna_reflex1.30975205
53MP0002064_seizures1.30629865
54MP0005187_abnormal_penis_morphology1.29503178
55MP0003136_yellow_coat_color1.28846863
56MP0002733_abnormal_thermal_nociception1.27638213
57MP0002752_abnormal_somatic_nervous1.24060045
58MP0002132_abnormal_respiratory_system1.23905823
59MP0002233_abnormal_nose_morphology1.21561121
60MP0003787_abnormal_imprinting1.20616151
61MP0004859_abnormal_synaptic_plasticity1.20610233
62MP0002736_abnormal_nociception_after1.19625699
63MP0010386_abnormal_urinary_bladder1.19473645
64MP0002882_abnormal_neuron_morphology1.16948808
65MP0004134_abnormal_chest_morphology1.16341460
66MP0002163_abnormal_gland_morphology1.16238687
67MP0002067_abnormal_sensory_capabilities1.13111946
68MP0008004_abnormal_stomach_pH1.12979794
69MP0003718_maternal_effect1.12703072
70MP0003806_abnormal_nucleotide_metabolis1.12559861
71MP0002161_abnormal_fertility/fecundity1.12010918
72MP0001502_abnormal_circadian_rhythm1.08637014
73MP0003011_delayed_dark_adaptation1.08281592
74MP0002928_abnormal_bile_duct1.07075947
75MP0001944_abnormal_pancreas_morphology1.06171061
76MP0001542_abnormal_bone_strength1.05650880
77MP0002876_abnormal_thyroid_physiology1.05037390
78MP0001986_abnormal_taste_sensitivity1.02910915
79MP0004019_abnormal_vitamin_homeostasis1.02181528
80MP0004142_abnormal_muscle_tone0.99843607
81MP0005423_abnormal_somatic_nervous0.97165315
82MP0010329_abnormal_lipoprotein_level0.96241694
83MP0005367_renal/urinary_system_phenotyp0.95932045
84MP0000516_abnormal_urinary_system0.95932045
85MP0000013_abnormal_adipose_tissue0.95300412
86MP0001756_abnormal_urination0.94493096
87MP0000230_abnormal_systemic_arterial0.93412995
88MP0005171_absent_coat_pigmentation0.93350311
89MP0000003_abnormal_adipose_tissue0.92818279
90MP0000631_abnormal_neuroendocrine_gland0.91354263
91MP0001963_abnormal_hearing_physiology0.90724400
92MP0009697_abnormal_copulation0.90529083
93MP0002234_abnormal_pharynx_morphology0.90476417
94MP0001970_abnormal_pain_threshold0.90387389
95MP0002152_abnormal_brain_morphology0.89474679
96MP0000647_abnormal_sebaceous_gland0.89336880
97MP0001145_abnormal_male_reproductive0.89056900
98MP0006072_abnormal_retinal_apoptosis0.88450744
99MP0003879_abnormal_hair_cell0.87428832
100MP0000026_abnormal_inner_ear0.85802996
101MP0000955_abnormal_spinal_cord0.85009537
102MP0005167_abnormal_blood-brain_barrier0.84366092
103MP0004215_abnormal_myocardial_fiber0.84262343
104MP0000653_abnormal_sex_gland0.83315896
105MP0001765_abnormal_ion_homeostasis0.83151224
106MP0002102_abnormal_ear_morphology0.82970915
107MP0003646_muscle_fatigue0.81829356
108MP0002229_neurodegeneration0.80755608
109MP0003122_maternal_imprinting0.79569492
110MP0001440_abnormal_grooming_behavior0.78747367
111MP0000049_abnormal_middle_ear0.77631274
112MP0004742_abnormal_vestibular_system0.76512616
113MP0003942_abnormal_urinary_system0.74285340
114MP0003861_abnormal_nervous_system0.71265126
115MP0002638_abnormal_pupillary_reflex0.71132775
116MP0001905_abnormal_dopamine_level0.67673385
117MP0002282_abnormal_trachea_morphology0.67623694
118MP0002009_preneoplasia0.67483271
119MP0004147_increased_porphyrin_level0.67110249
120MP0001501_abnormal_sleep_pattern0.66776209
121MP0002909_abnormal_adrenal_gland0.65887945
122MP0001529_abnormal_vocalization0.65632193
123MP0005253_abnormal_eye_physiology0.64463053
124MP0001177_atelectasis0.62368609
125MP0002751_abnormal_autonomic_nervous0.62184203
126MP0005195_abnormal_posterior_eye0.61781539
127MP0006292_abnormal_olfactory_placode0.61624177
128MP0005084_abnormal_gallbladder_morpholo0.61435802
129MP0004811_abnormal_neuron_physiology0.60634098
130MP0002735_abnormal_chemical_nociception0.60231942
131MP0004043_abnormal_pH_regulation0.59496599
132MP0008875_abnormal_xenobiotic_pharmacok0.58910556
133MP0009250_abnormal_appendicular_skeleto0.58580068

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.03673285
2Absent/shortened dynein arms (HP:0200106)8.22697176
3Dynein arm defect of respiratory motile cilia (HP:0012255)8.22697176
4Chronic bronchitis (HP:0004469)5.19710312
5Bronchiectasis (HP:0002110)5.07745715
6Nasal polyposis (HP:0100582)3.89828150
7Medial flaring of the eyebrow (HP:0010747)3.87192417
8Gait imbalance (HP:0002141)3.77840348
9Congenital primary aphakia (HP:0007707)3.70475426
10Nephronophthisis (HP:0000090)3.64836612
11Chronic sinusitis (HP:0011109)3.64438536
12Pancreatic fibrosis (HP:0100732)3.61100801
13Molar tooth sign on MRI (HP:0002419)3.60981178
14Abnormality of midbrain morphology (HP:0002418)3.60981178
15Recurrent sinusitis (HP:0011108)3.59844885
16Infertility (HP:0000789)3.53648080
17Nephrogenic diabetes insipidus (HP:0009806)3.47114401
18True hermaphroditism (HP:0010459)3.38814465
19Abnormality of the nasal mucosa (HP:0000433)3.01143193
20Tubulointerstitial nephritis (HP:0001970)2.96520355
21Vaginal atresia (HP:0000148)2.84493455
22Bronchitis (HP:0012387)2.83058246
23Poor coordination (HP:0002370)2.80626505
24Genital tract atresia (HP:0001827)2.80063460
25Abnormality of the renal medulla (HP:0100957)2.73457813
26Median cleft lip (HP:0000161)2.72842386
27Febrile seizures (HP:0002373)2.59921116
28Abnormality of macular pigmentation (HP:0008002)2.55497120
29Pancreatic cysts (HP:0001737)2.52151384
30Postaxial foot polydactyly (HP:0001830)2.47803641
31Aplasia/Hypoplasia of the lens (HP:0008063)2.39690881
32Congenital hepatic fibrosis (HP:0002612)2.39682074
33Occipital encephalocele (HP:0002085)2.37837291
34Recurrent otitis media (HP:0000403)2.37666827
35Hypothermia (HP:0002045)2.34217528
36Postaxial hand polydactyly (HP:0001162)2.33596382
37Atonic seizures (HP:0010819)2.33014162
38Polyphagia (HP:0002591)2.31565301
39Retinal dysplasia (HP:0007973)2.30725980
40Progressive cerebellar ataxia (HP:0002073)2.27518938
41Tubular atrophy (HP:0000092)2.27198426
42Severe visual impairment (HP:0001141)2.23106441
43Cystic liver disease (HP:0006706)2.22653319
44Bony spicule pigmentary retinopathy (HP:0007737)2.22143218
45Hemiparesis (HP:0001269)2.20108992
46Abnormality of the renal cortex (HP:0011035)2.19821091
47Abnormal rod and cone electroretinograms (HP:0008323)2.15924621
48Abnormality of the labia minora (HP:0012880)2.11010979
49Abnormality of dentin (HP:0010299)2.08075799
50Male pseudohermaphroditism (HP:0000037)2.06363154
51Oculomotor apraxia (HP:0000657)2.01375378
52Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.9662525
53Abnormal ciliary motility (HP:0012262)10.7765979
54Abnormal respiratory motile cilium physiology (HP:0012261)10.6853617
55Abnormal respiratory epithelium morphology (HP:0012253)10.3364167
56Abnormal respiratory motile cilium morphology (HP:0005938)10.3364167
57Aplasia/Hypoplasia of the tongue (HP:0010295)1.99074871
58Preaxial hand polydactyly (HP:0001177)1.96180512
59Supernumerary spleens (HP:0009799)1.95450015
60Chronic hepatic failure (HP:0100626)1.92328132
61Short tibia (HP:0005736)1.92065678
62Attenuation of retinal blood vessels (HP:0007843)1.90530625
63Aplasia/Hypoplasia of the spleen (HP:0010451)1.90137688
64Male infertility (HP:0003251)1.89949755
65Anencephaly (HP:0002323)1.89015146
66Stage 5 chronic kidney disease (HP:0003774)1.88180854
67Limb dystonia (HP:0002451)1.87434434
68Asplenia (HP:0001746)1.86812872
69Prolonged bleeding time (HP:0003010)1.86565621
70Large for gestational age (HP:0001520)1.86338886
713-Methylglutaconic aciduria (HP:0003535)1.86337438
72Aplasia/Hypoplasia of the tibia (HP:0005772)1.82784330
73Tubulointerstitial abnormality (HP:0001969)1.78037409
74Specific learning disability (HP:0001328)1.77988007
75Abnormality of the dental root (HP:0006486)1.76778086
76Taurodontia (HP:0000679)1.76778086
77Abnormality of permanent molar morphology (HP:0011071)1.76778086
78Absent speech (HP:0001344)1.75049108
79Facial cleft (HP:0002006)1.74606473
80Constricted visual fields (HP:0001133)1.73853888
81Congenital sensorineural hearing impairment (HP:0008527)1.73721713
82Menorrhagia (HP:0000132)1.73121883
83Hyperlipoproteinemia (HP:0010980)1.73081284
84Sclerocornea (HP:0000647)1.72584169
85Abolished electroretinogram (ERG) (HP:0000550)1.70617425
86Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.70265286
87Abnormality of alanine metabolism (HP:0010916)1.70265286
88Hyperalaninemia (HP:0003348)1.70265286
89Retinitis pigmentosa (HP:0000510)1.70059130
90Aplasia/Hypoplasia of the fovea (HP:0008060)1.68308936
91Hypoplasia of the fovea (HP:0007750)1.68308936
92Abnormality of molar (HP:0011077)1.68217915
93Abnormality of molar morphology (HP:0011070)1.68217915
94Hyperinsulinemic hypoglycemia (HP:0000825)1.67915691
95Abnormal sex determination (HP:0012244)1.67635922
96Sex reversal (HP:0012245)1.67635922
97Hyperventilation (HP:0002883)1.67441264
98Congenital stationary night blindness (HP:0007642)1.66805910
99Ketoacidosis (HP:0001993)1.65106001
100Epileptic encephalopathy (HP:0200134)1.64687143
101Optic nerve hypoplasia (HP:0000609)1.64480823
102Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63127726
103Hypoglycemic coma (HP:0001325)1.62878811
104Anosmia (HP:0000458)1.60651131
105Gaze-evoked nystagmus (HP:0000640)1.60556887
106Broad foot (HP:0001769)1.60404715
107Atelectasis (HP:0100750)1.59850371
108Abnormality of the fovea (HP:0000493)1.59835378
109Agitation (HP:0000713)1.57894453
110Hypsarrhythmia (HP:0002521)1.57188256
111EEG with generalized epileptiform discharges (HP:0011198)1.57123429
112Epileptiform EEG discharges (HP:0011182)1.56618852
113Abnormality of the dental pulp (HP:0006479)1.56112260
114Polyuria (HP:0000103)1.55459603
115Broad-based gait (HP:0002136)1.54799421
116Absent rod-and cone-mediated responses on ERG (HP:0007688)1.54528310
117Prolonged QT interval (HP:0001657)1.53809611
118Aplasia/hypoplasia of the uterus (HP:0008684)1.53470028
119Aganglionic megacolon (HP:0002251)1.51684447
120Bifid tongue (HP:0010297)1.48705144
121Nephropathy (HP:0000112)1.47575868
122Bell-shaped thorax (HP:0001591)1.43446124
123Abnormal biliary tract physiology (HP:0012439)1.43250898
124Bile duct proliferation (HP:0001408)1.43250898
125Syncope (HP:0001279)1.43011873
126Left ventricular hypertrophy (HP:0001712)1.42875857
127Degeneration of the lateral corticospinal tracts (HP:0002314)1.42810927
128Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.42810927
129Short foot (HP:0001773)1.40922250
130Absence seizures (HP:0002121)1.35972885
131Palpitations (HP:0001962)1.35152335
132Furrowed tongue (HP:0000221)1.35144172
133Fibular hypoplasia (HP:0003038)1.32427591
134Decreased central vision (HP:0007663)1.30132673
135Decreased testicular size (HP:0008734)1.29227243
136Abnormal drinking behavior (HP:0030082)1.29203874
137Polydipsia (HP:0001959)1.29203874
138Multicystic kidney dysplasia (HP:0000003)1.26262577
139Cutaneous syndactyly (HP:0012725)1.25829649
140Recurrent bronchitis (HP:0002837)1.25290202

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.40156724
2MAPKAPK33.78796312
3MAPK153.77768874
4PHKG23.66930339
5PHKG13.66930339
6MST43.51289389
7MAP4K22.84751235
8ERBB32.63029660
9PRPF4B2.60540285
10MAPK132.55769182
11WNK32.54768913
12MAPKAPK52.33648414
13STK162.21439898
14CASK2.19780081
15PDK42.18729429
16PDK32.18729429
17PNCK2.11514404
18NUAK12.09948630
19DAPK21.98258716
20PINK11.90416785
21EPHA41.82084186
22CDK121.75982719
23MAP2K71.74889240
24BMPR21.74811767
25TRPM71.64735332
26TNIK1.59888753
27TESK11.55517980
28BCR1.53893212
29FGFR21.53443630
30AKT31.52234629
31CAMKK21.47368720
32FER1.43920187
33TRIM281.41462862
34PDK21.39866266
35PLK41.39439188
36NTRK31.37337256
37CAMK2B1.36809279
38ACVR1B1.35005197
39CAMK1G1.29013334
40BRSK21.22438815
41PRKD31.19705959
42MUSK1.18069828
43INSRR1.17596723
44ICK1.17174254
45STK38L1.15289345
46CDK31.09969703
47NTRK21.09114422
48STK241.04359958
49DAPK11.03375626
50STK31.02788917
51ADRBK20.99537914
52SGK2230.99258319
53SGK4940.99258319
54ARAF0.96188378
55CAMK2D0.95868166
56WNK40.95646876
57SRPK10.95619318
58EIF2AK10.94233513
59SGK20.91729129
60RPS6KA20.90351218
61TLK10.89567941
62RPS6KB20.86685832
63RIPK40.86119619
64STK390.84361835
65MARK10.84114284
66MAP3K100.83931851
67PRKCG0.82981000
68EPHB20.82284798
69GRK10.80074894
70PLK30.77607242
71TNK20.76594783
72CSNK1G20.75819430
73MAP3K20.75226096
74RPS6KB10.74547791
75CAMK2G0.73363252
76PRKAA20.71600309
77IRAK10.71008883
78BRAF0.70718007
79CAMK2A0.70668669
80PRKCI0.70197900
81STK110.68516984
82HIPK20.68197785
83CAMK1D0.67590568
84ADRBK10.66946117
85CLK10.65132347
86DYRK30.65027563
87PLK20.64968413
88CSNK1G30.62529701
89MYLK0.62171867
90CSNK1A1L0.61948188
91STK380.60821036
92ZAK0.60457279
93SIK20.60431372
94PRKCZ0.57233272
95PTK2B0.57022211
96ERBB20.56408691
97BMPR1B0.55909625
98CAMKK10.55479777
99MAP3K40.55144637
100MINK10.53362122
101BMX0.51690645
102MAPK120.50529498
103FES0.48631937
104MARK20.47890886
105MAP2K60.47189347
106PRKCA0.47162366
107DYRK20.45865058
108MAP2K40.45251491
109PKN10.43725246
110PRKG10.42920576
111GRK50.42894614
112CSNK1A10.42191301
113IRAK20.40552757
114MAPKAPK20.40278871
115SIK30.39732518
116MKNK20.38935222
117WEE10.38822240
118DYRK1B0.37351798
119UHMK10.36632340
120ILK0.36151633
121FRK0.35836930
122VRK10.35085616
123PLK10.35065379
124PRKCE0.35002408
125YES10.34809451
126CSNK1G10.34467085
127EPHA30.32591678
128MAPK70.32368852
129PRKACA0.32355036
130CDK90.32214744
131CAMK10.31887356
132PAK30.31667074
133PRKAA10.29421808
134MAPK110.28995265
135OXSR10.28890001
136MAP3K140.28357038
137AURKA0.27326169
138CDK50.27213180
139WNK10.25342388
140DYRK1A0.25071219

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047407.54087197
2Phototransduction_Homo sapiens_hsa047443.83382085
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.54479975
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.99421262
5Butanoate metabolism_Homo sapiens_hsa006502.57976493
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.46143756
7Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.44158388
8Nicotine addiction_Homo sapiens_hsa050332.42073052
9Morphine addiction_Homo sapiens_hsa050322.39240299
10Collecting duct acid secretion_Homo sapiens_hsa049662.27320336
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.21993069
12Taste transduction_Homo sapiens_hsa047422.12395498
13Synaptic vesicle cycle_Homo sapiens_hsa047212.06111844
14Circadian entrainment_Homo sapiens_hsa047132.04578093
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.97216750
16Glutamatergic synapse_Homo sapiens_hsa047241.94876427
17Insulin secretion_Homo sapiens_hsa049111.91465718
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.91378914
19GABAergic synapse_Homo sapiens_hsa047271.89348740
20Huntingtons disease_Homo sapiens_hsa050161.81461039
21Oxidative phosphorylation_Homo sapiens_hsa001901.78487378
22Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.75541106
23Nitrogen metabolism_Homo sapiens_hsa009101.74595246
24Amphetamine addiction_Homo sapiens_hsa050311.58268958
25Steroid biosynthesis_Homo sapiens_hsa001001.57556009
26Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.48875065
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.46675034
28Dopaminergic synapse_Homo sapiens_hsa047281.42490172
29Vibrio cholerae infection_Homo sapiens_hsa051101.41269790
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.39595279
31Pyruvate metabolism_Homo sapiens_hsa006201.39049565
32Caffeine metabolism_Homo sapiens_hsa002321.38887116
33Ether lipid metabolism_Homo sapiens_hsa005651.28142418
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27292643
35Retinol metabolism_Homo sapiens_hsa008301.24758532
36Fatty acid elongation_Homo sapiens_hsa000621.24351715
37Renin secretion_Homo sapiens_hsa049241.23367449
38Calcium signaling pathway_Homo sapiens_hsa040201.23332052
39Selenocompound metabolism_Homo sapiens_hsa004501.21343092
40Cardiac muscle contraction_Homo sapiens_hsa042601.20290448
41Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.19228014
42Serotonergic synapse_Homo sapiens_hsa047261.18160938
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.17955994
44Alzheimers disease_Homo sapiens_hsa050101.16802231
45Glucagon signaling pathway_Homo sapiens_hsa049221.16571125
46Cholinergic synapse_Homo sapiens_hsa047251.15444718
47cAMP signaling pathway_Homo sapiens_hsa040241.14962761
48Parkinsons disease_Homo sapiens_hsa050121.14447204
49Salivary secretion_Homo sapiens_hsa049701.07779531
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.07024908
51Aldosterone synthesis and secretion_Homo sapiens_hsa049251.06823779
52Chemical carcinogenesis_Homo sapiens_hsa052041.05387036
53Ovarian steroidogenesis_Homo sapiens_hsa049131.01642211
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00692019
55Tyrosine metabolism_Homo sapiens_hsa003500.99462398
56Linoleic acid metabolism_Homo sapiens_hsa005910.97703402
57Regulation of autophagy_Homo sapiens_hsa041400.96988726
58Non-homologous end-joining_Homo sapiens_hsa034500.94923592
59Long-term potentiation_Homo sapiens_hsa047200.94416352
60Gastric acid secretion_Homo sapiens_hsa049710.90894827
61Hedgehog signaling pathway_Homo sapiens_hsa043400.90316043
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87737891
63Arachidonic acid metabolism_Homo sapiens_hsa005900.87370983
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.85969245
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.85407066
66Thyroid hormone synthesis_Homo sapiens_hsa049180.84046047
67Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83988106
68Tryptophan metabolism_Homo sapiens_hsa003800.83915364
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83561502
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82644949
71Circadian rhythm_Homo sapiens_hsa047100.81937736
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81107532
73ABC transporters_Homo sapiens_hsa020100.79276299
74Mineral absorption_Homo sapiens_hsa049780.78847591
75Propanoate metabolism_Homo sapiens_hsa006400.78415153
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77209655
77Oxytocin signaling pathway_Homo sapiens_hsa049210.76164577
78Glycerolipid metabolism_Homo sapiens_hsa005610.75571328
79Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75349139
80Alcoholism_Homo sapiens_hsa050340.74746673
81Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74037805
82Purine metabolism_Homo sapiens_hsa002300.71148912
83Histidine metabolism_Homo sapiens_hsa003400.70593898
84Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69874412
85Fatty acid degradation_Homo sapiens_hsa000710.69191205
86Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68661612
87Protein export_Homo sapiens_hsa030600.67744146
88Sulfur metabolism_Homo sapiens_hsa009200.67049255
89Arginine and proline metabolism_Homo sapiens_hsa003300.66373879
90Glutathione metabolism_Homo sapiens_hsa004800.64300837
91Estrogen signaling pathway_Homo sapiens_hsa049150.64287466
92Vitamin B6 metabolism_Homo sapiens_hsa007500.63055215
93Pancreatic secretion_Homo sapiens_hsa049720.62593005
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.62175761
95Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.60642231
96Cocaine addiction_Homo sapiens_hsa050300.59443421
97Starch and sucrose metabolism_Homo sapiens_hsa005000.57708858
98Sulfur relay system_Homo sapiens_hsa041220.57690930
99One carbon pool by folate_Homo sapiens_hsa006700.55674463
100Arginine biosynthesis_Homo sapiens_hsa002200.53553368
101Fanconi anemia pathway_Homo sapiens_hsa034600.52859094
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52061704
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51816608
104Homologous recombination_Homo sapiens_hsa034400.50994433
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.50489213
106Sphingolipid metabolism_Homo sapiens_hsa006000.50199889
107Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49795149
108Fatty acid biosynthesis_Homo sapiens_hsa000610.48339772
109Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47524446
110Melanogenesis_Homo sapiens_hsa049160.47034785
111Fat digestion and absorption_Homo sapiens_hsa049750.46909726
112Rheumatoid arthritis_Homo sapiens_hsa053230.44646758
113Axon guidance_Homo sapiens_hsa043600.44229106
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43351424
115Fatty acid metabolism_Homo sapiens_hsa012120.42155191
116Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.41312252
117Ras signaling pathway_Homo sapiens_hsa040140.38623376
118Peroxisome_Homo sapiens_hsa041460.36341771
119Bile secretion_Homo sapiens_hsa049760.36258588
120Phagosome_Homo sapiens_hsa041450.32595208
121beta-Alanine metabolism_Homo sapiens_hsa004100.31619624
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.30944049
123Basal transcription factors_Homo sapiens_hsa030220.29646113
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.27977741
125Phenylalanine metabolism_Homo sapiens_hsa003600.26415376
126Metabolic pathways_Homo sapiens_hsa011000.22479805
127Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.21703151
128Dilated cardiomyopathy_Homo sapiens_hsa054140.21668237
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20882475
130Type II diabetes mellitus_Homo sapiens_hsa049300.20739750
131Long-term depression_Homo sapiens_hsa047300.19269123
132Systemic lupus erythematosus_Homo sapiens_hsa053220.17563361
133Melanoma_Homo sapiens_hsa052180.16058501
134Fructose and mannose metabolism_Homo sapiens_hsa000510.15190373
135MAPK signaling pathway_Homo sapiens_hsa040100.14661945
136Prion diseases_Homo sapiens_hsa050200.14596473

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »