RSRP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.77344883
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.77344883
3positive regulation of gamma-delta T cell activation (GO:0046645)5.69605629
4antigen processing and presentation via MHC class Ib (GO:0002475)5.03078983
5antigen processing and presentation of endogenous antigen (GO:0019883)5.00026301
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.85863365
7regulation of gamma-delta T cell differentiation (GO:0045586)4.40621313
8regulation of gamma-delta T cell activation (GO:0046643)4.29875957
9negative regulation of erythrocyte differentiation (GO:0045647)4.16340038
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.07447682
11immunoglobulin mediated immune response (GO:0016064)3.88839070
12negative regulation of lymphocyte mediated immunity (GO:0002707)3.84564533
13cellular extravasation (GO:0045123)3.83162439
14positive regulation of B cell differentiation (GO:0045579)3.78609070
15histone H3-K4 trimethylation (GO:0080182)3.75712770
16negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.73362757
17negative regulation of cell killing (GO:0031342)3.73362757
18detection of other organism (GO:0098543)3.72807112
19cellular response to interleukin-15 (GO:0071350)3.70975814
20detection of bacterium (GO:0016045)3.70207960
21positive regulation of granulocyte differentiation (GO:0030854)3.62444783
22neutrophil activation involved in immune response (GO:0002283)3.53182798
23negative regulation of T cell mediated immunity (GO:0002710)3.51423489
24modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.42025921
25positive regulation by organism of defense response of other organism involved in symbiotic interact3.42025921
26modulation by symbiont of host immune response (GO:0052553)3.42025921
27positive regulation by symbiont of host defense response (GO:0052509)3.42025921
28modulation by symbiont of host defense response (GO:0052031)3.42025921
29modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.42025921
30B cell receptor signaling pathway (GO:0050853)3.41928043
31negative regulation of leukocyte mediated immunity (GO:0002704)3.40488329
32regulation of B cell differentiation (GO:0045577)3.36990572
33regulation of germinal center formation (GO:0002634)3.35272664
34microglial cell activation (GO:0001774)3.31857888
35response to peptidoglycan (GO:0032494)3.31601857
36regulation of B cell receptor signaling pathway (GO:0050855)3.31535395
37leukocyte aggregation (GO:0070486)3.25347303
38regulation of alpha-beta T cell proliferation (GO:0046640)3.24961603
39regulation of regulatory T cell differentiation (GO:0045589)3.24329687
40valine metabolic process (GO:0006573)3.23457237
41positive regulation of cellular amide metabolic process (GO:0034250)3.20267580
42neutrophil activation (GO:0042119)3.19615070
43negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.16909425
44positive regulation of respiratory burst (GO:0060267)3.15695330
45activated T cell proliferation (GO:0050798)3.15642841
46regulation of histone H3-K27 methylation (GO:0061085)3.13441719
47germinal center formation (GO:0002467)3.11461016
48regulation of dendritic cell antigen processing and presentation (GO:0002604)3.10605023
49positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.08835655
50regulation of antigen processing and presentation (GO:0002577)3.08566697
51negative regulation of glycoprotein biosynthetic process (GO:0010561)3.07603133
52response to type I interferon (GO:0034340)3.03596815
53detection of external biotic stimulus (GO:0098581)3.03080107
54neutrophil mediated immunity (GO:0002446)3.02966316
55negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.02677150
56regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.02365825
57mast cell activation (GO:0045576)3.01146180
58B cell mediated immunity (GO:0019724)3.00571311
59cellular response to type I interferon (GO:0071357)2.97589940
60type I interferon signaling pathway (GO:0060337)2.97589940
61negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.95870600
62myeloid cell activation involved in immune response (GO:0002275)2.95783520
63negative regulation of interleukin-12 production (GO:0032695)2.95383957
64positive thymic T cell selection (GO:0045059)2.94347970
65tolerance induction (GO:0002507)2.92988844
66negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.92915791
67negative regulation of T-helper cell differentiation (GO:0045623)2.92915791
68macrophage activation involved in immune response (GO:0002281)2.92908440
69regulation of interferon-beta biosynthetic process (GO:0045357)2.92719965
70Arp2/3 complex-mediated actin nucleation (GO:0034314)2.90548958
71mannose metabolic process (GO:0006013)2.89797313
72positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.88857308
73negative regulation of adaptive immune response (GO:0002820)2.87431637
74regulation of beta-amyloid formation (GO:1902003)2.85116551
75defense response to protozoan (GO:0042832)2.84690317
76regulation of mast cell activation (GO:0033003)2.82950336
77mast cell degranulation (GO:0043303)2.81404045
78mast cell activation involved in immune response (GO:0002279)2.81404045
79negative regulation of innate immune response (GO:0045824)2.80226772
80regulation of mast cell degranulation (GO:0043304)2.78677986
81positive regulation of alpha-beta T cell proliferation (GO:0046641)2.77683676
82granulocyte activation (GO:0036230)2.76428245
83regulation of tolerance induction (GO:0002643)2.75939528
84response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.75592523
85response to host immune response (GO:0052572)2.75592523
86secretory granule organization (GO:0033363)2.74510246
87T cell receptor signaling pathway (GO:0050852)2.74411327
88regulation of memory T cell differentiation (GO:0043380)2.74308697
89positive regulation of triglyceride biosynthetic process (GO:0010867)2.72676811
90cellular response to exogenous dsRNA (GO:0071360)2.70614276
91regulation of natural killer cell mediated immunity (GO:0002715)2.70116885
92regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.70116885
93positive regulation of histone deacetylation (GO:0031065)2.69651068
94regulation of leukocyte mediated cytotoxicity (GO:0001910)2.69064874
95negative T cell selection (GO:0043383)2.67943756
96negative regulation of stress fiber assembly (GO:0051497)2.66043751
97positive regulation of natural killer cell activation (GO:0032816)2.65550356
98regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.65211437
99myeloid leukocyte mediated immunity (GO:0002444)2.64228273
100response to protozoan (GO:0001562)2.62159332
101T cell homeostasis (GO:0043029)2.61924435
102regulation of granulocyte differentiation (GO:0030852)2.61175437
103megakaryocyte development (GO:0035855)2.60638790
104regulation of cellular amide metabolic process (GO:0034248)2.60541796
105negative thymic T cell selection (GO:0045060)2.56282818
106regulation of T cell receptor signaling pathway (GO:0050856)2.55959195
107Golgi to endosome transport (GO:0006895)2.55836421
108positive T cell selection (GO:0043368)2.55720724
109phosphatidylethanolamine biosynthetic process (GO:0006646)2.54530395
110negative regulation of glycoprotein metabolic process (GO:1903019)2.52598180
111response to interleukin-15 (GO:0070672)2.51520715
112T cell migration (GO:0072678)2.51227038
113Peyers patch development (GO:0048541)2.49123194
114mucosal-associated lymphoid tissue development (GO:0048537)2.49123194
115definitive hemopoiesis (GO:0060216)2.46262467
116positive regulation of natural killer cell differentiation (GO:0032825)2.45554700
117adaptation of signaling pathway (GO:0023058)2.45063246
118tricarboxylic acid metabolic process (GO:0072350)2.44998867
119response to interferon-alpha (GO:0035455)2.44133281
120necroptotic process (GO:0070266)2.41985706
121regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.41340671
122regulation of natural killer cell activation (GO:0032814)2.40966678
123antigen receptor-mediated signaling pathway (GO:0050851)2.40356260
124regulation of erythrocyte differentiation (GO:0045646)2.38353522
125phosphatidylethanolamine metabolic process (GO:0046337)2.36640581
126interferon-gamma production (GO:0032609)2.35924712
127interferon-gamma-mediated signaling pathway (GO:0060333)2.35780977
128positive regulation of T cell mediated cytotoxicity (GO:0001916)2.34094925
129programmed necrotic cell death (GO:0097300)2.32262014
130leukocyte homeostasis (GO:0001776)2.31725230
131regulation of T cell mediated cytotoxicity (GO:0001914)2.31651112
132positive regulation of antigen processing and presentation (GO:0002579)2.31540531
133beta-amyloid metabolic process (GO:0050435)2.31035185
134negative regulation of interleukin-17 production (GO:0032700)2.30734181
135lymphocyte homeostasis (GO:0002260)2.30223466
136T cell selection (GO:0045058)2.27177555
137lymph node development (GO:0048535)2.26913080
138peptidyl-lysine trimethylation (GO:0018023)2.26900178
139regulation of interleukin-12 biosynthetic process (GO:0045075)2.25742760
140mature B cell differentiation (GO:0002335)2.25447557
141regulation of necroptotic process (GO:0060544)2.24400708
142response to muramyl dipeptide (GO:0032495)2.24147030
143lymphoid progenitor cell differentiation (GO:0002320)2.23969568
144serine transport (GO:0032329)2.21569478
145COPI coating of Golgi vesicle (GO:0048205)2.21324919
146Golgi transport vesicle coating (GO:0048200)2.21324919
147positive regulation of protein deacetylation (GO:0090312)2.21000250
148NIK/NF-kappaB signaling (GO:0038061)2.20250370
149regulation of amyloid precursor protein catabolic process (GO:1902991)2.18230649
150necrotic cell death (GO:0070265)2.17923868
151thymic T cell selection (GO:0045061)2.15636172
152leukocyte degranulation (GO:0043299)2.15439090

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.54654385
2GATA1_22025678_ChIP-Seq_K562_Human4.48637464
3SCL_19346495_ChIP-Seq_HPC-7_Human3.98062609
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.52872975
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.40191647
6RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.90929102
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.75388301
8SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.65777606
9VDR_21846776_ChIP-Seq_THP-1_Human2.63046538
10LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.41905502
11RUNX_20019798_ChIP-Seq_JUKART_Human2.34964425
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.34126127
13NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.31478032
14MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.27182662
15E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.26489427
16FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.26387003
17MYB_21317192_ChIP-Seq_ERMYB_Mouse2.16495432
18IRF8_27001747_Chip-Seq_BMDM_Mouse2.15896411
19FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.11265407
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.10202734
21VDR_24763502_ChIP-Seq_THP-1_Human2.09263249
22GATA1_19941827_ChIP-Seq_MEL_Mouse2.06524529
23MYC_22102868_ChIP-Seq_BL_Human2.02978983
24TCF7_22412390_ChIP-Seq_EML_Mouse2.01706483
25ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.98633633
26MYB_26560356_Chip-Seq_TH2_Human1.97354432
27MAF_26560356_Chip-Seq_TH1_Human1.95564480
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.95145499
29SPI1_23127762_ChIP-Seq_K562_Human1.91147806
30LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.90865545
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.88317315
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86989223
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.82164670
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.81080325
35MYB_26560356_Chip-Seq_TH1_Human1.77496000
36VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77248117
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.76916113
38UTX_26944678_Chip-Seq_JUKART_Human1.76846879
39SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.74298373
40GATA1_22383799_ChIP-Seq_G1ME_Mouse1.73743800
41VDR_24787735_ChIP-Seq_THP-1_Human1.72117046
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.70898181
43TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.69577305
44SPI1_23547873_ChIP-Seq_NB4_Human1.69397826
45GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.61497695
46LXR_22292898_ChIP-Seq_THP-1_Human1.60955890
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.60492277
48RXR_22158963_ChIP-Seq_LIVER_Mouse1.59635313
49STAT4_19710469_ChIP-ChIP_TH1__Mouse1.54013819
50VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.53891565
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48965956
52CIITA_25753668_ChIP-Seq_RAJI_Human1.48361852
53KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47746656
54GATA3_27048872_Chip-Seq_THYMUS_Human1.46700176
55KDM2B_26808549_Chip-Seq_DND41_Human1.44686681
56ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43188262
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.42248114
58GATA1_19941826_ChIP-Seq_K562_Human1.41394476
59KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.40009837
60GATA2_22383799_ChIP-Seq_G1ME_Mouse1.37925982
61PPARA_22158963_ChIP-Seq_LIVER_Mouse1.36656288
62KDM2B_26808549_Chip-Seq_SUP-B15_Human1.36021298
63GATA2_21666600_ChIP-Seq_HMVEC_Human1.35123196
64PU_27001747_Chip-Seq_BMDM_Mouse1.30816790
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29014572
66GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.26767896
67SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.23211177
68MAF_26560356_Chip-Seq_TH2_Human1.23117386
69ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21201394
70RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.20188363
71FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.20066599
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.18988306
73PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.17337242
74CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15299303
75ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14650628
76DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13621740
77DROSHA_22980978_ChIP-Seq_HELA_Human1.13578093
78GATA2_19941826_ChIP-Seq_K562_Human1.13342408
79GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12064980
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09296068
81CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09022871
82RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.07880610
83PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05590425
84Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.05244676
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04948906
86LXR_22158963_ChIP-Seq_LIVER_Mouse1.04941224
87ELK3_25401928_ChIP-Seq_HUVEC_Human1.04172255
88GATA3_26560356_Chip-Seq_TH2_Human1.02484456
89SMRT_27268052_Chip-Seq_Bcells_Human1.01162510
90GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01038872
91SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.00397572
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.00067283
93SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.99203477
94BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96624797
95CTCF_21964334_ChIP-Seq_BJAB-B_Human0.96171266
96PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95870762
97SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.94310537
98EGR1_23403033_ChIP-Seq_LIVER_Mouse0.94133549
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94116528
100NOTCH1_21737748_ChIP-Seq_TLL_Human0.93064616
101SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91732519
102P300_27268052_Chip-Seq_Bcells_Human0.90000942
103CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89764919
104BCL6_27268052_Chip-Seq_Bcells_Human0.89088573
105CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88668259
106GATA3_26560356_Chip-Seq_TH1_Human0.88446948
107TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87370568
108ELF1_20517297_ChIP-Seq_JURKAT_Human0.87274726
109RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.86106760
110BP1_19119308_ChIP-ChIP_Hs578T_Human0.85615800
111BCOR_27268052_Chip-Seq_Bcells_Human0.85333633
112KDM2B_26808549_Chip-Seq_JURKAT_Human0.84911251
113BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.84665493
114ETS1_22383799_ChIP-Seq_G1ME_Mouse0.84637034
115EGR1_19374776_ChIP-ChIP_THP-1_Human0.84552160
116PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84437926
117CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.84086630
118RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83839097
119NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.82283112
120TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.80255702
121FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80104203
122CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79201479
123STAT1_20625510_ChIP-Seq_HELA_Human0.78919271
124ER_23166858_ChIP-Seq_MCF-7_Human0.78552916
125PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.78496027
126GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.74312100

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003183_abnormal_peptide_metabolism3.10276840
2MP0001835_abnormal_antigen_presentation3.09659360
3MP0000685_abnormal_immune_system2.92496204
4MP0002166_altered_tumor_susceptibility2.74364008
5MP0005671_abnormal_response_to2.68751019
6MP0005174_abnormal_tail_pigmentation2.65345937
7MP0003172_abnormal_lysosome_physiology2.64737011
8MP0000569_abnormal_digit_pigmentation2.43841315
9MP0005058_abnormal_lysosome_morphology2.37408608
10MP0003763_abnormal_thymus_physiology2.23531186
11MP0001873_stomach_inflammation2.18225647
12MP0001790_abnormal_immune_system2.12625967
13MP0005387_immune_system_phenotype2.12625967
14MP0001800_abnormal_humoral_immune2.10496423
15MP0005464_abnormal_platelet_physiology2.10151554
16MP0005025_abnormal_response_to1.98668843
17MP0002396_abnormal_hematopoietic_system1.98316134
18MP0009785_altered_susceptibility_to1.94090131
19MP0002419_abnormal_innate_immunity1.92230467
20MP0003300_gastrointestinal_ulcer1.92077042
21MP0002723_abnormal_immune_serum1.87798012
22MP0002420_abnormal_adaptive_immunity1.81740325
23MP0001819_abnormal_immune_cell1.79037139
24MP0002909_abnormal_adrenal_gland1.78706415
25MP0002452_abnormal_antigen_presenting1.77533469
26MP0005000_abnormal_immune_tolerance1.75959787
27MP0001533_abnormal_skeleton_physiology1.75668602
28MP0000465_gastrointestinal_hemorrhage1.74465057
29MP0002006_tumorigenesis1.72013441
30MP0005365_abnormal_bile_salt1.69786602
31MP0002398_abnormal_bone_marrow1.66378675
32MP0003436_decreased_susceptibility_to1.63579766
33MP0004130_abnormal_muscle_cell1.62978584
34MP0009840_abnormal_foam_cell1.62531519
35MP0003866_abnormal_defecation1.60803746
36MP0003191_abnormal_cellular_cholesterol1.60081511
37MP0009333_abnormal_splenocyte_physiolog1.54480614
38MP0000716_abnormal_immune_system1.50892107
39MP0001853_heart_inflammation1.48511422
40MP0005075_abnormal_melanosome_morpholog1.48355045
41MP0001986_abnormal_taste_sensitivity1.48110466
42MP0004947_skin_inflammation1.47386493
43MP0002254_reproductive_system_inflammat1.45617562
44MP0010155_abnormal_intestine_physiology1.42505980
45MP0003724_increased_susceptibility_to1.41520735
46MP0003656_abnormal_erythrocyte_physiolo1.40158394
47MP0002148_abnormal_hypersensitivity_rea1.37693325
48MP0005397_hematopoietic_system_phenotyp1.36605784
49MP0001545_abnormal_hematopoietic_system1.36605784
50MP0002693_abnormal_pancreas_physiology1.36509333
51MP0002132_abnormal_respiratory_system1.36323720
52MP0000689_abnormal_spleen_morphology1.36067274
53MP0002928_abnormal_bile_duct1.34434030
54MP0008469_abnormal_protein_level1.30221518
55MP0001851_eye_inflammation1.27892633
56MP0002722_abnormal_immune_system1.27410449
57MP0001845_abnormal_inflammatory_respons1.27153050
58MP0000604_amyloidosis1.25967121
59MP0002638_abnormal_pupillary_reflex1.25739275
60MP0008961_abnormal_basal_metabolism1.24574655
61MP0002429_abnormal_blood_cell1.24340587
62MP0002009_preneoplasia1.23734759
63MP0004381_abnormal_hair_follicle1.21585426
64MP0003828_pulmonary_edema1.21005271
65MP0010329_abnormal_lipoprotein_level1.18526671
66MP0005310_abnormal_salivary_gland1.14094916
67MP0002095_abnormal_skin_pigmentation1.13987053
68MP0002138_abnormal_hepatobiliary_system1.12562079
69MP0000703_abnormal_thymus_morphology1.12495744
70MP0000015_abnormal_ear_pigmentation1.09927647
71MP0003868_abnormal_feces_composition1.09176946
72MP0005379_endocrine/exocrine_gland_phen1.06679968
73MP0003045_fibrosis1.06612158
74MP0002405_respiratory_system_inflammati1.06419050
75MP0001502_abnormal_circadian_rhythm1.04560003
76MP0004147_increased_porphyrin_level1.04356844
77MP0000609_abnormal_liver_physiology1.03608043
78MP0001944_abnormal_pancreas_morphology1.03543505
79MP0001765_abnormal_ion_homeostasis1.02239181
80MP0005584_abnormal_enzyme/coenzyme_acti1.01859324
81MP0002139_abnormal_hepatobiliary_system1.01739182
82MP0004883_abnormal_blood_vessel1.01163324
83MP0001666_abnormal_nutrient_absorption0.99905634
84MP0003329_amyloid_beta_deposits0.97929754
85MP0009764_decreased_sensitivity_to0.97838577
86MP0002998_abnormal_bone_remodeling0.97557750
87MP0005083_abnormal_biliary_tract0.97471487
88MP0008569_lethality_at_weaning0.97317767
89MP0002078_abnormal_glucose_homeostasis0.95074293
90MP0002118_abnormal_lipid_homeostasis0.92103708
91MP0003075_altered_response_to0.91932932
92MP0003252_abnormal_bile_duct0.91713077
93MP0005220_abnormal_exocrine_pancreas0.91349487
94MP0009643_abnormal_urine_homeostasis0.88880148
95MP0001501_abnormal_sleep_pattern0.86530249
96MP0001663_abnormal_digestive_system0.86330469
97MP0003303_peritoneal_inflammation0.85857623
98MP0004808_abnormal_hematopoietic_stem0.85784657
99MP0009278_abnormal_bone_marrow0.85351439
100MP0002971_abnormal_brown_adipose0.84475538
101MP0004043_abnormal_pH_regulation0.84305183
102MP0009765_abnormal_xenobiotic_induced0.82107729
103MP0004484_altered_response_of0.82063355
104MP0005535_abnormal_body_temperature0.81384390
105MP0005164_abnormal_response_to0.80024762
106MP0005636_abnormal_mineral_homeostasis0.79568861
107MP0005166_decreased_susceptibility_to0.79548912
108MP0008875_abnormal_xenobiotic_pharmacok0.78389895
109MP0009763_increased_sensitivity_to0.77918631
110MP0004510_myositis0.77763975
111MP0005551_abnormal_eye_electrophysiolog0.77176389
112MP0000013_abnormal_adipose_tissue0.76728038
113MP0002277_abnormal_respiratory_mucosa0.76638389
114MP0002933_joint_inflammation0.76478648
115MP0000371_diluted_coat_color0.75625424
116MP0008260_abnormal_autophagy0.75416737
117MP0009642_abnormal_blood_homeostasis0.75361063
118MP0005334_abnormal_fat_pad0.75178819
119MP0000249_abnormal_blood_vessel0.74712860
120MP0005167_abnormal_blood-brain_barrier0.74673962
121MP0006082_CNS_inflammation0.73492641
122MP0003690_abnormal_glial_cell0.72138595
123MP0003879_abnormal_hair_cell0.71584977
124MP0000858_altered_metastatic_potential0.69221387
125MP0005390_skeleton_phenotype0.68228649
126MP0002136_abnormal_kidney_physiology0.64867902
127MP0002019_abnormal_tumor_incidence0.62857186
128MP0003787_abnormal_imprinting0.56491795
129MP0008004_abnormal_stomach_pH0.55140237
130MP0003795_abnormal_bone_structure0.53975522
131MP0005451_abnormal_body_composition0.52447696
132MP0009115_abnormal_fat_cell0.51833885
133MP0005376_homeostasis/metabolism_phenot0.49521670

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)4.16943285
2Orchitis (HP:0100796)4.09514971
3Retrobulbar optic neuritis (HP:0100654)4.08835782
4Optic neuritis (HP:0100653)4.08835782
5Chronic otitis media (HP:0000389)4.01404906
6Panhypogammaglobulinemia (HP:0003139)3.89856140
7Hypoplasia of the thymus (HP:0000778)3.72537679
8Encephalitis (HP:0002383)3.60530952
9Recurrent viral infections (HP:0004429)3.47075173
10Chronic obstructive pulmonary disease (HP:0006510)3.42131795
11Obstructive lung disease (HP:0006536)3.42131795
12Gastrointestinal infarctions (HP:0005244)3.41268149
13Abnormal delayed hypersensitivity skin test (HP:0002963)3.36166474
14Elevated erythrocyte sedimentation rate (HP:0003565)3.27059955
15Recurrent fungal infections (HP:0002841)3.25732228
16Prolonged bleeding time (HP:0003010)3.18020751
17Leukocytosis (HP:0001974)3.16127715
18Recurrent gram-negative bacterial infections (HP:0005420)3.14614643
19Pulmonary infiltrates (HP:0002113)3.13230070
20Recurrent bacterial skin infections (HP:0005406)3.13098094
21Abnormality of B cell number (HP:0010975)3.09338936
22B lymphocytopenia (HP:0010976)3.09338936
23Recurrent abscess formation (HP:0002722)3.05759926
24Dysostosis multiplex (HP:0000943)3.03046559
25Recurrent cutaneous fungal infections (HP:0011370)3.00750690
26Chronic mucocutaneous candidiasis (HP:0002728)3.00750690
27Vacuolated lymphocytes (HP:0001922)2.99774489
28Inflammation of the large intestine (HP:0002037)2.98414748
29Abnormality of eosinophils (HP:0001879)2.94956178
30Keratoconjunctivitis sicca (HP:0001097)2.93931852
31Hemoptysis (HP:0002105)2.91638213
32Gastrointestinal inflammation (HP:0004386)2.91327512
33Chest pain (HP:0100749)2.88496253
34Colitis (HP:0002583)2.88486341
35Spontaneous hematomas (HP:0007420)2.84610988
36Keratoconjunctivitis (HP:0001096)2.84386479
37Autoimmune hemolytic anemia (HP:0001890)2.83012967
38Stomach cancer (HP:0012126)2.77978148
39Recurrent skin infections (HP:0001581)2.77680813
40Abnormality of the fingertips (HP:0001211)2.77060117
41IgG deficiency (HP:0004315)2.74621658
42Agammaglobulinemia (HP:0004432)2.74330423
43Hypoproteinemia (HP:0003075)2.73010509
44Decreased circulating renin level (HP:0003351)2.72879032
45Recurrent bronchitis (HP:0002837)2.72211015
46IgM deficiency (HP:0002850)2.70576981
47Absent rod-and cone-mediated responses on ERG (HP:0007688)2.68819104
48Abnormality of glycosaminoglycan metabolism (HP:0004371)2.66712143
49Abnormality of mucopolysaccharide metabolism (HP:0011020)2.66712143
50Abnormality of polysaccharide metabolism (HP:0011012)2.66712143
51Epistaxis (HP:0000421)2.65240394
52Increased cerebral lipofuscin (HP:0011813)2.64887386
53Myositis (HP:0100614)2.59606840
54Impaired platelet aggregation (HP:0003540)2.55100472
55Abnormal platelet function (HP:0011869)2.55100472
56Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.55046630
57Abnormality of the pleura (HP:0002103)2.54859052
58Cellulitis (HP:0100658)2.52071002
59Pulmonary embolism (HP:0002204)2.51737246
60T lymphocytopenia (HP:0005403)2.50693859
61Increased neuronal autofluorescent lipopigment (HP:0002074)2.50648864
62Abnormality of the prostate (HP:0008775)2.47838029
63Recurrent sinusitis (HP:0011108)2.47249933
64Urticaria (HP:0001025)2.45272583
65Arterial thrombosis (HP:0004420)2.44632264
66Mucopolysacchariduria (HP:0008155)2.43860478
67Urinary glycosaminoglycan excretion (HP:0003541)2.43860478
68Abnormality of T cells (HP:0002843)2.42937532
69Abnormality of T cell physiology (HP:0011840)2.41296816
70Loss of speech (HP:0002371)2.40080558
71Gingival bleeding (HP:0000225)2.39170045
72Thoracic kyphosis (HP:0002942)2.35835503
73Supranuclear gaze palsy (HP:0000605)2.35128414
74Eczematoid dermatitis (HP:0000976)2.34759056
75Thyroiditis (HP:0100646)2.34039745
76Abnormal rod and cone electroretinograms (HP:0008323)2.31119785
77Papilledema (HP:0001085)2.30459228
78Increased IgM level (HP:0003496)2.30197271
79Abnormality of T cell number (HP:0011839)2.30123591
80Gastrointestinal stroma tumor (HP:0100723)2.29462070
81Meningitis (HP:0001287)2.29017157
82Absent/shortened dynein arms (HP:0200106)2.28789072
83Dynein arm defect of respiratory motile cilia (HP:0012255)2.28789072
84Hypochromic anemia (HP:0001931)2.28016275
85Hypergammaglobulinemia (HP:0010702)2.26561341
86Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.25292881
87Chronic diarrhea (HP:0002028)2.23498522
88Hypochromic microcytic anemia (HP:0004840)2.22855287
89Mediastinal lymphadenopathy (HP:0100721)2.22732471
90Periodontitis (HP:0000704)2.21753468
91Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.20554506
92Hypoglycemic coma (HP:0001325)2.19820131
93Hypothermia (HP:0002045)2.18285261
94Combined immunodeficiency (HP:0005387)2.18165686
95Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.18034128
96Abnormality of liposaccharide metabolism (HP:0010968)2.17516967
97Abnormality of glycosphingolipid metabolism (HP:0004343)2.17516967
98Abnormality of glycolipid metabolism (HP:0010969)2.17516967
99Gangrene (HP:0100758)2.16608533
100Neurodegeneration (HP:0002180)2.15614519
101Ketoacidosis (HP:0001993)2.14996578
102Fatigue (HP:0012378)2.14571011
103Slow saccadic eye movements (HP:0000514)2.13337475
104Increased IgE level (HP:0003212)2.12131307
105Ketosis (HP:0001946)2.11783936
106Nasal polyposis (HP:0100582)2.11595536
107Late onset (HP:0003584)2.11591557
108Alveolar cell carcinoma (HP:0006519)2.11288572
109Thrombocytosis (HP:0001894)2.10661472
110Sepsis (HP:0100806)2.10273948
111Abnormality of the nasal mucosa (HP:0000433)2.09909611
112Severe combined immunodeficiency (HP:0004430)2.09124462
113Interstitial pulmonary disease (HP:0006530)2.07143343
114Hypoglycemic seizures (HP:0002173)2.04228435
115Abnormality of macrophages (HP:0004311)2.03817442
116Neoplasm of the tracheobronchial system (HP:0100552)2.03447254
117Bronchitis (HP:0012387)2.02030145
118Acute lymphatic leukemia (HP:0006721)2.01478756
119Episodic fever (HP:0001954)2.00432819
120Anorexia (HP:0002039)1.99492042
121Microcytic anemia (HP:0001935)1.98774995
122Reduced antithrombin III activity (HP:0001976)1.97876924
123Abnormality of the heme biosynthetic pathway (HP:0010472)1.96718535
124Granulocytopenia (HP:0001913)1.95414182
125Progressive neurologic deterioration (HP:0002344)1.94644935
126Abnormality of the thoracic spine (HP:0100711)1.94611486
127Osteomyelitis (HP:0002754)1.94592576
128Autoimmune thrombocytopenia (HP:0001973)1.94176597
129Petechiae (HP:0000967)1.94015062
130Broad face (HP:0000283)1.93528583
131Thyroid-stimulating hormone excess (HP:0002925)1.92685321
132Joint swelling (HP:0001386)1.92457473
133Symptomatic seizures (HP:0011145)1.91728312
134Chronic sinusitis (HP:0011109)1.90964186
135Skin rash (HP:0000988)1.90761001
136Generalized aminoaciduria (HP:0002909)1.90299819
137Abnormality of cells of the lymphoid lineage (HP:0012140)1.89549044
138Keratitis (HP:0000491)1.89052276
139Papilloma (HP:0012740)1.88486099
140Verrucae (HP:0200043)1.88486099
141Vasculitis (HP:0002633)1.85570174
142Amyloidosis (HP:0011034)1.84368166
143Emphysema (HP:0002097)1.84082545
144Gingivitis (HP:0000230)1.82669592
145Eosinophilia (HP:0001880)1.80784098
146Aplastic anemia (HP:0001915)1.80668207
147Restrictive lung disease (HP:0002091)1.79163528
148Abnormality of aromatic amino acid family metabolism (HP:0004338)1.78094372
149Lymphopenia (HP:0001888)1.78052706
150Pustule (HP:0200039)1.77781538

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KIT3.48661226
2TNIK3.25324978
3FLT32.97662892
4TAOK32.87009560
5MAP3K132.86464132
6ERN12.72516058
7MAP4K12.68879926
8INSRR2.64686778
9FRK2.35345357
10SIK22.11081198
11RIPK42.05203708
12TYK22.01056390
13JAK31.92264334
14IKBKE1.88678307
15BTK1.87586755
16TEC1.80448168
17FES1.62609952
18TBK11.60974462
19BMPR21.59585067
20ZAP701.58129268
21IRAK41.56049509
22TXK1.55560285
23MAP3K71.51852347
24FGFR41.50128332
25MAPK151.49506243
26CSF1R1.46440080
27JAK11.44610322
28BRD41.42266108
29HIPK21.37406159
30SYK1.36564636
31SIK11.34129365
32TGFBR21.34092553
33CAMKK21.28944432
34ITK1.22148846
35MARK31.12696827
36HCK1.10489932
37MAP3K141.10084514
38BCKDK1.08927105
39CAMK11.06269608
40LCK1.05727930
41IRAK31.04627343
42BLK1.02022073
43JAK21.00846386
44MAP2K31.00829228
45MARK21.00159300
46SCYL20.99968826
47ACVR1B0.99660433
48TESK20.98628808
49MAPKAPK30.97630597
50TRIB30.97374707
51CAMK1D0.97052975
52CAMK1G0.95920598
53GRK60.95455618
54PIK3CG0.92437313
55MUSK0.91686892
56PKN20.91601550
57PTK60.89389976
58RIPK10.88529296
59FGR0.87041163
60STK160.84396791
61LYN0.84307833
62PTK2B0.84231402
63EEF2K0.82882072
64TTN0.81500119
65ADRBK20.81344590
66NLK0.81237220
67MAPK110.80591695
68DYRK1B0.79123299
69YES10.79031722
70EPHA40.78182520
71TLK10.75975908
72TRPM70.73908847
73PIM10.73610107
74MAPK120.73243791
75PRKAA20.72437644
76CDK190.69441653
77MAP3K10.67733767
78FGFR30.66338860
79DYRK30.66086555
80LRRK20.65885144
81TNK20.65604485
82MAP3K110.65129199
83MATK0.64963350
84MAP2K20.64513668
85PRPF4B0.64366930
86MAP3K60.63167377
87PHKG10.60364059
88PHKG20.60364059
89DAPK10.60273558
90PRKD20.59325272
91EPHA30.58386468
92CSK0.55732824
93SIK30.54436802
94DYRK1A0.54289457
95RAF10.52580199
96BMPR1B0.52460234
97PDPK10.50790890
98GRK70.50575358
99KSR20.50439799
100RPS6KA60.50363252
101NTRK30.50002111
102FYN0.49754941
103KDR0.49567241
104CDC42BPA0.48776949
105PRKCH0.48026688
106CAMKK10.47359796
107ABL10.46411811
108DAPK20.46078801
109EPHB10.45402452
110MAPK130.44062872
111CAMK40.43646923
112CHUK0.43432765
113MAP3K20.43432547
114MAP4K20.42987552
115IRAK10.42579972
116IKBKB0.42086361
117RPS6KL10.42082479
118RPS6KC10.42082479
119MAP2K60.41361449
120STK380.40737204
121CLK10.40432275
122STK110.39877179
123PDK10.38851434
124RET0.38291486
125MAP2K70.38048533
126IRAK20.38022214
127MAP2K40.37530230
128PRKCQ0.37509623
129MAPK70.36802891
130MAP3K100.36151484
131PINK10.35879842
132ADRBK10.34965302
133MAPK30.34820263
134MAP3K50.33424843
135PIK3CA0.33114471
136WNK10.31458114
137OXSR10.30087208
138PRKD10.29597501
139NUAK10.28993341

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.41932662
2Primary immunodeficiency_Homo sapiens_hsa053403.40919640
3Allograft rejection_Homo sapiens_hsa053303.33593363
4Autoimmune thyroid disease_Homo sapiens_hsa053203.15390474
5Caffeine metabolism_Homo sapiens_hsa002323.12194969
6Asthma_Homo sapiens_hsa053102.87362855
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.85532473
8Type I diabetes mellitus_Homo sapiens_hsa049402.51994319
9ABC transporters_Homo sapiens_hsa020102.18143154
10B cell receptor signaling pathway_Homo sapiens_hsa046622.16955778
11Other glycan degradation_Homo sapiens_hsa005112.08567200
12Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.00664127
13Hematopoietic cell lineage_Homo sapiens_hsa046401.71911921
14Carbohydrate digestion and absorption_Homo sapiens_hsa049731.69928892
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.64241873
16Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.61550296
17Viral myocarditis_Homo sapiens_hsa054161.59835818
18Glycosaminoglycan degradation_Homo sapiens_hsa005311.57643176
19Osteoclast differentiation_Homo sapiens_hsa043801.57433767
20Lysosome_Homo sapiens_hsa041421.52690053
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.44143278
22Leishmaniasis_Homo sapiens_hsa051401.41804961
23T cell receptor signaling pathway_Homo sapiens_hsa046601.38156946
24Acute myeloid leukemia_Homo sapiens_hsa052211.34362399
25Measles_Homo sapiens_hsa051621.29675168
26Rheumatoid arthritis_Homo sapiens_hsa053231.29306426
27Fatty acid degradation_Homo sapiens_hsa000711.27936745
28Toll-like receptor signaling pathway_Homo sapiens_hsa046201.27809082
29Type II diabetes mellitus_Homo sapiens_hsa049301.26765647
30Lysine degradation_Homo sapiens_hsa003101.24265698
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.24075670
32Insulin resistance_Homo sapiens_hsa049311.22392371
33Malaria_Homo sapiens_hsa051441.21857869
34Insulin secretion_Homo sapiens_hsa049111.19936878
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.19694822
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.18367700
37Sulfur relay system_Homo sapiens_hsa041221.17630875
38NF-kappa B signaling pathway_Homo sapiens_hsa040641.16775902
39Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.12536993
40N-Glycan biosynthesis_Homo sapiens_hsa005101.08487336
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07423657
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05759525
43Jak-STAT signaling pathway_Homo sapiens_hsa046301.05647155
44Antigen processing and presentation_Homo sapiens_hsa046121.03566290
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.98955471
46Intestinal immune network for IgA production_Homo sapiens_hsa046720.98929923
47Circadian rhythm_Homo sapiens_hsa047100.98436657
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.97581785
49Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97107284
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.96733700
51Herpes simplex infection_Homo sapiens_hsa051680.96546267
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.96535239
53Legionellosis_Homo sapiens_hsa051340.96222769
54Regulation of autophagy_Homo sapiens_hsa041400.95456330
55Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.95082538
56Influenza A_Homo sapiens_hsa051640.94933728
57African trypanosomiasis_Homo sapiens_hsa051430.91378130
58NOD-like receptor signaling pathway_Homo sapiens_hsa046210.89471121
59Tuberculosis_Homo sapiens_hsa051520.89452464
60Platelet activation_Homo sapiens_hsa046110.87151068
61Protein export_Homo sapiens_hsa030600.86309899
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86271547
63Linoleic acid metabolism_Homo sapiens_hsa005910.85905462
64Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.85330853
65Adipocytokine signaling pathway_Homo sapiens_hsa049200.85174780
66Pancreatic secretion_Homo sapiens_hsa049720.82302754
67Staphylococcus aureus infection_Homo sapiens_hsa051500.80808985
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80762760
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.80188788
70Peroxisome_Homo sapiens_hsa041460.79881321
71Phototransduction_Homo sapiens_hsa047440.79235469
72Chemokine signaling pathway_Homo sapiens_hsa040620.78093333
73Starch and sucrose metabolism_Homo sapiens_hsa005000.74759390
74Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74662182
75Phagosome_Homo sapiens_hsa041450.74223005
76Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73896736
77Hepatitis C_Homo sapiens_hsa051600.73750056
78Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.71571074
79Toxoplasmosis_Homo sapiens_hsa051450.71263781
80Pertussis_Homo sapiens_hsa051330.69221393
81Galactose metabolism_Homo sapiens_hsa000520.69000561
82Arachidonic acid metabolism_Homo sapiens_hsa005900.68704645
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68475545
84Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.67114872
85Dorso-ventral axis formation_Homo sapiens_hsa043200.66920171
86Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65641665
87Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64865492
88Insulin signaling pathway_Homo sapiens_hsa049100.62625495
89cAMP signaling pathway_Homo sapiens_hsa040240.61757060
90Circadian entrainment_Homo sapiens_hsa047130.61535697
91Glycerolipid metabolism_Homo sapiens_hsa005610.61115400
92Non-small cell lung cancer_Homo sapiens_hsa052230.60541093
93Morphine addiction_Homo sapiens_hsa050320.60255033
94Nitrogen metabolism_Homo sapiens_hsa009100.58771403
95Folate biosynthesis_Homo sapiens_hsa007900.57526342
96Neurotrophin signaling pathway_Homo sapiens_hsa047220.57387045
97Bile secretion_Homo sapiens_hsa049760.56324815
98Fatty acid metabolism_Homo sapiens_hsa012120.55926312
99Prolactin signaling pathway_Homo sapiens_hsa049170.55609563
100Gastric acid secretion_Homo sapiens_hsa049710.55227364
101PPAR signaling pathway_Homo sapiens_hsa033200.54563937
102Sphingolipid metabolism_Homo sapiens_hsa006000.54411733
103Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54119360
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.54024655
105Hepatitis B_Homo sapiens_hsa051610.53921212
106Apoptosis_Homo sapiens_hsa042100.53895421
107Chronic myeloid leukemia_Homo sapiens_hsa052200.52446154
108Ether lipid metabolism_Homo sapiens_hsa005650.52161474
109Calcium signaling pathway_Homo sapiens_hsa040200.51809691
110Notch signaling pathway_Homo sapiens_hsa043300.51777610
111TNF signaling pathway_Homo sapiens_hsa046680.51643925
112Tryptophan metabolism_Homo sapiens_hsa003800.49821139
113VEGF signaling pathway_Homo sapiens_hsa043700.47867320
114Inositol phosphate metabolism_Homo sapiens_hsa005620.47606866
115Glucagon signaling pathway_Homo sapiens_hsa049220.47476804
116Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45976596
117FoxO signaling pathway_Homo sapiens_hsa040680.44889399
118Thyroid hormone synthesis_Homo sapiens_hsa049180.44785632
119Epstein-Barr virus infection_Homo sapiens_hsa051690.44412682
120Systemic lupus erythematosus_Homo sapiens_hsa053220.44262779
121Leukocyte transendothelial migration_Homo sapiens_hsa046700.43977421
122Complement and coagulation cascades_Homo sapiens_hsa046100.43794022
123Choline metabolism in cancer_Homo sapiens_hsa052310.42636795
124Salivary secretion_Homo sapiens_hsa049700.41571743
125Pancreatic cancer_Homo sapiens_hsa052120.41098073
126Selenocompound metabolism_Homo sapiens_hsa004500.39968038
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.39783923
128Sulfur metabolism_Homo sapiens_hsa009200.38915428
129MAPK signaling pathway_Homo sapiens_hsa040100.38842481
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.38767371
131Shigellosis_Homo sapiens_hsa051310.38668329
132Taste transduction_Homo sapiens_hsa047420.38631927
133Salmonella infection_Homo sapiens_hsa051320.37622942
134mTOR signaling pathway_Homo sapiens_hsa041500.36056551
135HTLV-I infection_Homo sapiens_hsa051660.35809521
136Olfactory transduction_Homo sapiens_hsa047400.35060189
137Vascular smooth muscle contraction_Homo sapiens_hsa042700.33800762
138Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.33085162
139Viral carcinogenesis_Homo sapiens_hsa052030.30913035
140Renin secretion_Homo sapiens_hsa049240.30866926
141GnRH signaling pathway_Homo sapiens_hsa049120.28937344
142Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28560303
143AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.25127629

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