

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.28674843 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.92789788 |
| 3 | sleep (GO:0030431) | 4.78008705 |
| 4 | DNA double-strand break processing (GO:0000729) | 4.51142166 |
| 5 | protein neddylation (GO:0045116) | 4.50210182 |
| 6 | cytidine metabolic process (GO:0046087) | 4.40476258 |
| 7 | cytidine catabolic process (GO:0006216) | 4.40476258 |
| 8 | cytidine deamination (GO:0009972) | 4.40476258 |
| 9 | mannosylation (GO:0097502) | 4.06967825 |
| 10 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.98573144 |
| 11 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.98573144 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 3.98205602 |
| 13 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.96992926 |
| 14 | RNA destabilization (GO:0050779) | 3.82393155 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.79534848 |
| 16 | rRNA methylation (GO:0031167) | 3.73513711 |
| 17 | mismatch repair (GO:0006298) | 3.61966544 |
| 18 | protein deneddylation (GO:0000338) | 3.60437848 |
| 19 | cullin deneddylation (GO:0010388) | 3.59709289 |
| 20 | adenosine metabolic process (GO:0046085) | 3.58636977 |
| 21 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.50861628 |
| 22 | isotype switching (GO:0045190) | 3.50861628 |
| 23 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.50861628 |
| 24 | rRNA modification (GO:0000154) | 3.50593136 |
| 25 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.50421424 |
| 26 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.50421424 |
| 27 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.45361055 |
| 28 | ribosome assembly (GO:0042255) | 3.41331401 |
| 29 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.40195915 |
| 30 | platelet dense granule organization (GO:0060155) | 3.25210001 |
| 31 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.23729812 |
| 32 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.22699714 |
| 33 | regulation of regulatory T cell differentiation (GO:0045589) | 3.21447448 |
| 34 | cellular response to interleukin-15 (GO:0071350) | 3.19718584 |
| 35 | actin nucleation (GO:0045010) | 3.16955647 |
| 36 | endoderm formation (GO:0001706) | 3.12636018 |
| 37 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.11920835 |
| 38 | proteasome assembly (GO:0043248) | 3.08589909 |
| 39 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.06562641 |
| 40 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.99806727 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.95607795 |
| 42 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.94546830 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.93520855 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.93520855 |
| 45 | tolerance induction (GO:0002507) | 2.90502439 |
| 46 | fucose catabolic process (GO:0019317) | 2.87798943 |
| 47 | L-fucose metabolic process (GO:0042354) | 2.87798943 |
| 48 | L-fucose catabolic process (GO:0042355) | 2.87798943 |
| 49 | regulation of fibroblast apoptotic process (GO:2000269) | 2.87278252 |
| 50 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.87031946 |
| 51 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.87031946 |
| 52 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.87031946 |
| 53 | positive regulation of defense response to virus by host (GO:0002230) | 2.86949892 |
| 54 | maturation of 5.8S rRNA (GO:0000460) | 2.86294599 |
| 55 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.85918709 |
| 56 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.84337466 |
| 57 | inner mitochondrial membrane organization (GO:0007007) | 2.83774100 |
| 58 | deoxyribose phosphate catabolic process (GO:0046386) | 2.83404162 |
| 59 | protein K6-linked ubiquitination (GO:0085020) | 2.82692770 |
| 60 | leukocyte degranulation (GO:0043299) | 2.78920703 |
| 61 | negative regulation of ligase activity (GO:0051352) | 2.75335529 |
| 62 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.75335529 |
| 63 | mast cell activation (GO:0045576) | 2.74371952 |
| 64 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.74118294 |
| 65 | positive regulation of mRNA catabolic process (GO:0061014) | 2.73173357 |
| 66 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.73114107 |
| 67 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.73114107 |
| 68 | metallo-sulfur cluster assembly (GO:0031163) | 2.71917782 |
| 69 | iron-sulfur cluster assembly (GO:0016226) | 2.71917782 |
| 70 | mast cell activation involved in immune response (GO:0002279) | 2.71749244 |
| 71 | mast cell degranulation (GO:0043303) | 2.71749244 |
| 72 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.70752137 |
| 73 | histone H2A acetylation (GO:0043968) | 2.69601665 |
| 74 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.66936234 |
| 75 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.66936234 |
| 76 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.66716804 |
| 77 | somatic diversification of immunoglobulins (GO:0016445) | 2.66353048 |
| 78 | regulation of cellular extravasation (GO:0002691) | 2.65219767 |
| 79 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.64736542 |
| 80 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.64139863 |
| 81 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.64139863 |
| 82 | DNA demethylation (GO:0080111) | 2.60944287 |
| 83 | positive regulation of mRNA 3-end processing (GO:0031442) | 2.60884733 |
| 84 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.60477739 |
| 85 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.60360502 |
| 86 | negative regulation of meiotic cell cycle (GO:0051447) | 2.60343387 |
| 87 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.60328441 |
| 88 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.59472639 |
| 89 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.59178488 |
| 90 | response to nitrosative stress (GO:0051409) | 2.58179263 |
| 91 | piRNA metabolic process (GO:0034587) | 2.58069135 |
| 92 | plasma membrane fusion (GO:0045026) | 2.57799143 |
| 93 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.53273990 |
| 94 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.53273990 |
| 95 | chromatin remodeling at centromere (GO:0031055) | 2.52631204 |
| 96 | base-excision repair, AP site formation (GO:0006285) | 2.52618558 |
| 97 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.52552371 |
| 98 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.52546455 |
| 99 | ATP synthesis coupled proton transport (GO:0015986) | 2.52107917 |
| 100 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.52107917 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.55877019 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.12997648 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.66852127 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.43438702 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.28329955 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.19114813 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91753024 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.90358311 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.83632528 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.63420913 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.51355539 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.51141433 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.43928063 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38779046 |
| 15 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.25980535 |
| 16 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.22268189 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.21607019 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.14412572 |
| 19 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.88069170 |
| 20 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.81395266 |
| 21 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.80937488 |
| 22 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.77639701 |
| 23 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.76174062 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.73714065 |
| 25 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.67595203 |
| 26 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.67437230 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.64580475 |
| 28 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63425978 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.61954463 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.61751931 |
| 31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.59682396 |
| 32 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55192319 |
| 33 | GATA3_26560356_Chip-Seq_TH2_Human | 1.53781488 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.50353735 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47978535 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47746275 |
| 37 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.42256933 |
| 38 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.37142245 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.36943015 |
| 40 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.36691346 |
| 41 | EWS_26573619_Chip-Seq_HEK293_Human | 1.35908440 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.34577799 |
| 43 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.34282809 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33722514 |
| 45 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.33096388 |
| 46 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.32570709 |
| 47 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.32570709 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.31287054 |
| 49 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30717991 |
| 50 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.30640800 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29703531 |
| 52 | MYB_26560356_Chip-Seq_TH2_Human | 1.27377303 |
| 53 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.25160382 |
| 54 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24769527 |
| 55 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.24247123 |
| 56 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.22679192 |
| 57 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.22049142 |
| 58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21090749 |
| 59 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.20246796 |
| 60 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19957003 |
| 61 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19616416 |
| 62 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15469406 |
| 63 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.15130042 |
| 64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.13032458 |
| 65 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.08049175 |
| 66 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.05780165 |
| 67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05428390 |
| 68 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.05243149 |
| 69 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04929773 |
| 70 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04929773 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.04525644 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.04525644 |
| 73 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.04394305 |
| 74 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.04253685 |
| 75 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03981116 |
| 76 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.03820559 |
| 77 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.03816362 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03583237 |
| 79 | VDR_22108803_ChIP-Seq_LS180_Human | 1.03201991 |
| 80 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02570718 |
| 81 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00918425 |
| 82 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.99036089 |
| 83 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94097768 |
| 84 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.93906746 |
| 85 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92964416 |
| 86 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92622378 |
| 87 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.92181180 |
| 88 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.92132415 |
| 89 | GATA3_26560356_Chip-Seq_TH1_Human | 0.91631915 |
| 90 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.91581797 |
| 91 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.91238564 |
| 92 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90629477 |
| 93 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89236297 |
| 94 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88457493 |
| 95 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87514888 |
| 96 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87240199 |
| 97 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.86314912 |
| 98 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.86197657 |
| 99 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.85483325 |
| 100 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.85407595 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 3.91804216 |
| 2 | MP0003724_increased_susceptibility_to | 3.67908615 |
| 3 | MP0005671_abnormal_response_to | 3.31505667 |
| 4 | MP0002009_preneoplasia | 2.84479413 |
| 5 | MP0009697_abnormal_copulation | 2.84243624 |
| 6 | MP0005167_abnormal_blood-brain_barrier | 2.82279836 |
| 7 | MP0002254_reproductive_system_inflammat | 2.67933468 |
| 8 | MP0006054_spinal_hemorrhage | 2.67080299 |
| 9 | MP0000465_gastrointestinal_hemorrhage | 2.66251823 |
| 10 | MP0004147_increased_porphyrin_level | 2.52380706 |
| 11 | MP0010368_abnormal_lymphatic_system | 2.48970334 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 2.47432258 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 2.33587320 |
| 14 | MP0008995_early_reproductive_senescence | 2.31558329 |
| 15 | MP0003786_premature_aging | 2.30918635 |
| 16 | MP0008775_abnormal_heart_ventricle | 2.27642613 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.19227931 |
| 18 | MP0002166_altered_tumor_susceptibility | 2.07330352 |
| 19 | MP0008877_abnormal_DNA_methylation | 2.01886307 |
| 20 | MP0003763_abnormal_thymus_physiology | 1.97739249 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.85511433 |
| 22 | MP0001879_abnormal_lymphatic_vessel | 1.80473852 |
| 23 | MP0002933_joint_inflammation | 1.79793424 |
| 24 | MP0003436_decreased_susceptibility_to | 1.78584770 |
| 25 | MP0002006_tumorigenesis | 1.74196766 |
| 26 | MP0004782_abnormal_surfactant_physiolog | 1.67151560 |
| 27 | MP0005000_abnormal_immune_tolerance | 1.64557189 |
| 28 | MP0008872_abnormal_physiological_respon | 1.60300658 |
| 29 | MP0003806_abnormal_nucleotide_metabolis | 1.56692548 |
| 30 | MP0005253_abnormal_eye_physiology | 1.55638283 |
| 31 | MP0002736_abnormal_nociception_after | 1.53118884 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.52343841 |
| 33 | MP0010094_abnormal_chromosome_stability | 1.50305000 |
| 34 | MP0008004_abnormal_stomach_pH | 1.46552457 |
| 35 | MP0005075_abnormal_melanosome_morpholog | 1.45721307 |
| 36 | MP0002876_abnormal_thyroid_physiology | 1.40897555 |
| 37 | MP0009764_decreased_sensitivity_to | 1.39031934 |
| 38 | MP0009840_abnormal_foam_cell | 1.37668002 |
| 39 | MP0008058_abnormal_DNA_repair | 1.34270150 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.33922841 |
| 41 | MP0003718_maternal_effect | 1.33298063 |
| 42 | MP0006276_abnormal_autonomic_nervous | 1.32509873 |
| 43 | MP0003191_abnormal_cellular_cholesterol | 1.32359544 |
| 44 | MP0001529_abnormal_vocalization | 1.27128712 |
| 45 | MP0004215_abnormal_myocardial_fiber | 1.22804299 |
| 46 | MP0002822_catalepsy | 1.19238589 |
| 47 | MP0001835_abnormal_antigen_presentation | 1.13145955 |
| 48 | MP0004957_abnormal_blastocyst_morpholog | 1.11813443 |
| 49 | MP0001819_abnormal_immune_cell | 1.10464671 |
| 50 | MP0006036_abnormal_mitochondrial_physio | 1.10292782 |
| 51 | MP0003011_delayed_dark_adaptation | 1.10199068 |
| 52 | MP0000685_abnormal_immune_system | 1.09933582 |
| 53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09298362 |
| 54 | MP0002420_abnormal_adaptive_immunity | 1.07821215 |
| 55 | MP0004947_skin_inflammation | 1.07498479 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 1.06974920 |
| 57 | MP0002452_abnormal_antigen_presenting | 1.06930584 |
| 58 | MP0002723_abnormal_immune_serum | 1.06805141 |
| 59 | MP0001533_abnormal_skeleton_physiology | 1.04483603 |
| 60 | MP0000689_abnormal_spleen_morphology | 1.02372655 |
| 61 | MP0002398_abnormal_bone_marrow | 1.02005929 |
| 62 | MP0004133_heterotaxia | 0.99612474 |
| 63 | MP0005410_abnormal_fertilization | 0.98537712 |
| 64 | MP0001853_heart_inflammation | 0.97380445 |
| 65 | MP0004145_abnormal_muscle_electrophysio | 0.94681619 |
| 66 | MP0001919_abnormal_reproductive_system | 0.89895929 |
| 67 | MP0005083_abnormal_biliary_tract | 0.89303012 |
| 68 | MP0001501_abnormal_sleep_pattern | 0.87846066 |
| 69 | MP0001800_abnormal_humoral_immune | 0.86599189 |
| 70 | MP0005499_abnormal_olfactory_system | 0.86489010 |
| 71 | MP0005394_taste/olfaction_phenotype | 0.86489010 |
| 72 | MP0003866_abnormal_defecation | 0.82683299 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.82006207 |
| 74 | MP0002405_respiratory_system_inflammati | 0.81516468 |
| 75 | MP0002429_abnormal_blood_cell | 0.80679650 |
| 76 | MP0000372_irregular_coat_pigmentation | 0.79845320 |
| 77 | MP0001243_abnormal_dermal_layer | 0.79294755 |
| 78 | MP0002722_abnormal_immune_system | 0.79268765 |
| 79 | MP0000716_abnormal_immune_system | 0.78335749 |
| 80 | MP0009763_increased_sensitivity_to | 0.78219722 |
| 81 | MP0005365_abnormal_bile_salt | 0.74932178 |
| 82 | MP0000230_abnormal_systemic_arterial | 0.72835072 |
| 83 | MP0001986_abnormal_taste_sensitivity | 0.72704031 |
| 84 | MP0003638_abnormal_response/metabolism_ | 0.72698598 |
| 85 | MP0001929_abnormal_gametogenesis | 0.72004662 |
| 86 | MP0001544_abnormal_cardiovascular_syste | 0.71606196 |
| 87 | MP0005385_cardiovascular_system_phenoty | 0.71606196 |
| 88 | MP0002419_abnormal_innate_immunity | 0.70483001 |
| 89 | MP0010155_abnormal_intestine_physiology | 0.70247802 |
| 90 | MP0005647_abnormal_sex_gland | 0.69489279 |
| 91 | MP0006138_congestive_heart_failure | 0.69392678 |
| 92 | MP0003186_abnormal_redox_activity | 0.69029298 |
| 93 | MP0000249_abnormal_blood_vessel | 0.68072655 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.68055314 |
| 95 | MP0005389_reproductive_system_phenotype | 0.67602619 |
| 96 | MP0001968_abnormal_touch/_nociception | 0.66479398 |
| 97 | MP0008260_abnormal_autophagy | 0.66326531 |
| 98 | MP0010386_abnormal_urinary_bladder | 0.64921130 |
| 99 | MP0000358_abnormal_cell_content/ | 0.64898204 |
| 100 | MP0008007_abnormal_cellular_replicative | 0.64864086 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IgG deficiency (HP:0004315) | 4.58056853 |
| 2 | Stomatitis (HP:0010280) | 3.92672655 |
| 3 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.67085638 |
| 4 | Abnormal protein glycosylation (HP:0012346) | 3.67085638 |
| 5 | Abnormal glycosylation (HP:0012345) | 3.67085638 |
| 6 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.67085638 |
| 7 | Congenital, generalized hypertrichosis (HP:0004540) | 3.58214447 |
| 8 | Type I transferrin isoform profile (HP:0003642) | 3.37400446 |
| 9 | Stomach cancer (HP:0012126) | 3.25362949 |
| 10 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.21834003 |
| 11 | Severe combined immunodeficiency (HP:0004430) | 3.19490771 |
| 12 | Hypoplasia of the pons (HP:0012110) | 3.04745349 |
| 13 | Abnormality of alanine metabolism (HP:0010916) | 3.02883966 |
| 14 | Hyperalaninemia (HP:0003348) | 3.02883966 |
| 15 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.02883966 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 2.99931566 |
| 17 | Abnormality of the pons (HP:0007361) | 2.94235321 |
| 18 | Abolished electroretinogram (ERG) (HP:0000550) | 2.93993692 |
| 19 | Hepatocellular necrosis (HP:0001404) | 2.91349669 |
| 20 | Tongue fasciculations (HP:0001308) | 2.81177436 |
| 21 | Abnormality of eosinophils (HP:0001879) | 2.75769953 |
| 22 | IgM deficiency (HP:0002850) | 2.73435374 |
| 23 | IgA deficiency (HP:0002720) | 2.70835470 |
| 24 | Neonatal respiratory distress (HP:0002643) | 2.61578461 |
| 25 | Hepatic necrosis (HP:0002605) | 2.61159265 |
| 26 | Increased CSF lactate (HP:0002490) | 2.60471226 |
| 27 | Mitochondrial inheritance (HP:0001427) | 2.56522242 |
| 28 | Hematochezia (HP:0002573) | 2.52368134 |
| 29 | Acute encephalopathy (HP:0006846) | 2.50413693 |
| 30 | Combined immunodeficiency (HP:0005387) | 2.50011210 |
| 31 | Increased IgM level (HP:0003496) | 2.47779334 |
| 32 | Renal cortical cysts (HP:0000803) | 2.47748600 |
| 33 | Eosinophilia (HP:0001880) | 2.46941362 |
| 34 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.46728559 |
| 35 | Abnormality of B cell number (HP:0010975) | 2.41654539 |
| 36 | Methylmalonic acidemia (HP:0002912) | 2.38424288 |
| 37 | Increased serum lactate (HP:0002151) | 2.38327788 |
| 38 | Acute necrotizing encephalopathy (HP:0006965) | 2.37072329 |
| 39 | Abnormality of the anterior horn cell (HP:0006802) | 2.36351118 |
| 40 | Degeneration of anterior horn cells (HP:0002398) | 2.36351118 |
| 41 | T lymphocytopenia (HP:0005403) | 2.33220902 |
| 42 | Facial diplegia (HP:0001349) | 2.31985150 |
| 43 | Aplastic anemia (HP:0001915) | 2.31334039 |
| 44 | Hyperglycinemia (HP:0002154) | 2.30855689 |
| 45 | Muscle fibrillation (HP:0010546) | 2.29357363 |
| 46 | Abnormality of T cells (HP:0002843) | 2.26537007 |
| 47 | Abnormality of T cell number (HP:0011839) | 2.24832431 |
| 48 | Abnormal spermatogenesis (HP:0008669) | 2.21153280 |
| 49 | Abnormality of T cell physiology (HP:0011840) | 2.19059524 |
| 50 | Short tibia (HP:0005736) | 2.18907753 |
| 51 | B lymphocytopenia (HP:0010976) | 2.10913812 |
| 52 | Abnormality of the fovea (HP:0000493) | 2.10881302 |
| 53 | Fair hair (HP:0002286) | 2.10328315 |
| 54 | Lactic acidosis (HP:0003128) | 2.09782256 |
| 55 | Methylmalonic aciduria (HP:0012120) | 2.09046618 |
| 56 | Progressive microcephaly (HP:0000253) | 2.07836055 |
| 57 | Pancytopenia (HP:0001876) | 2.06680714 |
| 58 | Dry hair (HP:0011359) | 2.05884017 |
| 59 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.05592069 |
| 60 | Albinism (HP:0001022) | 2.03710159 |
| 61 | Thyroid-stimulating hormone excess (HP:0002925) | 2.03603947 |
| 62 | Medial flaring of the eyebrow (HP:0010747) | 2.03371497 |
| 63 | Increased serum pyruvate (HP:0003542) | 2.01823720 |
| 64 | Cerebellar dysplasia (HP:0007033) | 1.99084061 |
| 65 | Increased hepatocellular lipid droplets (HP:0006565) | 1.98950049 |
| 66 | Petechiae (HP:0000967) | 1.96640218 |
| 67 | Leukocytosis (HP:0001974) | 1.93906489 |
| 68 | Hypomagnesemia (HP:0002917) | 1.93501855 |
| 69 | Neoplasm of head and neck (HP:0012288) | 1.93288128 |
| 70 | Esophageal neoplasm (HP:0100751) | 1.93288128 |
| 71 | Cerebral palsy (HP:0100021) | 1.92038446 |
| 72 | Hypothermia (HP:0002045) | 1.91130040 |
| 73 | Neutropenia (HP:0001875) | 1.89651648 |
| 74 | Attenuation of retinal blood vessels (HP:0007843) | 1.88963282 |
| 75 | Inability to walk (HP:0002540) | 1.87586763 |
| 76 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.86437867 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.86118586 |
| 78 | Opisthotonus (HP:0002179) | 1.84496811 |
| 79 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.83745537 |
| 80 | Hypoplasia of the fovea (HP:0007750) | 1.83745537 |
| 81 | Abnormality of serum amino acid levels (HP:0003112) | 1.83063902 |
| 82 | Colon cancer (HP:0003003) | 1.82670426 |
| 83 | Type II lissencephaly (HP:0007260) | 1.82122638 |
| 84 | Progressive macrocephaly (HP:0004481) | 1.81293489 |
| 85 | Thyroiditis (HP:0100646) | 1.81285118 |
| 86 | Pancreatic cysts (HP:0001737) | 1.81009486 |
| 87 | Poor head control (HP:0002421) | 1.80622304 |
| 88 | Abnormality of glycolysis (HP:0004366) | 1.80536055 |
| 89 | Prominent metopic ridge (HP:0005487) | 1.80358300 |
| 90 | Pulmonary fibrosis (HP:0002206) | 1.80289315 |
| 91 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.79828307 |
| 92 | Nephronophthisis (HP:0000090) | 1.79294407 |
| 93 | Pendular nystagmus (HP:0012043) | 1.78361715 |
| 94 | Reduced antithrombin III activity (HP:0001976) | 1.77679404 |
| 95 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.76806482 |
| 96 | Congenital stationary night blindness (HP:0007642) | 1.76210351 |
| 97 | Lipid accumulation in hepatocytes (HP:0006561) | 1.76106596 |
| 98 | Abnormality of the renal cortex (HP:0011035) | 1.75792027 |
| 99 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.74067750 |
| 100 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.74067750 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 6.49356187 |
| 2 | ZAK | 4.52781100 |
| 3 | MST4 | 3.32217395 |
| 4 | TAOK3 | 2.90580418 |
| 5 | TLK1 | 2.74921940 |
| 6 | TXK | 2.26687565 |
| 7 | TRIM28 | 2.22756170 |
| 8 | GRK1 | 2.17646571 |
| 9 | TEC | 2.09934000 |
| 10 | ACVR1B | 2.08725797 |
| 11 | GRK6 | 2.06877444 |
| 12 | BUB1 | 1.88037015 |
| 13 | TESK2 | 1.87144939 |
| 14 | SRPK1 | 1.85615466 |
| 15 | FES | 1.80514097 |
| 16 | BCKDK | 1.77426091 |
| 17 | PLK4 | 1.74460746 |
| 18 | MAP4K2 | 1.64065823 |
| 19 | BMPR1B | 1.58627795 |
| 20 | VRK1 | 1.58281979 |
| 21 | ERBB3 | 1.49117265 |
| 22 | EPHA3 | 1.43010362 |
| 23 | WNK3 | 1.39509635 |
| 24 | NUAK1 | 1.39256076 |
| 25 | LIMK1 | 1.29499478 |
| 26 | ZAP70 | 1.23191944 |
| 27 | WNK4 | 1.21843474 |
| 28 | FER | 1.20468400 |
| 29 | KDR | 1.16953995 |
| 30 | PLK3 | 1.16857575 |
| 31 | PLK2 | 1.14170614 |
| 32 | TESK1 | 1.13766968 |
| 33 | ADRBK2 | 1.13588089 |
| 34 | BCR | 1.11058828 |
| 35 | NEK1 | 1.08795819 |
| 36 | TTK | 1.05916801 |
| 37 | MAP2K2 | 1.03149403 |
| 38 | SIK3 | 0.90145214 |
| 39 | JAK1 | 0.88942215 |
| 40 | INSRR | 0.88850370 |
| 41 | TSSK6 | 0.86897936 |
| 42 | EPHB1 | 0.85823159 |
| 43 | IKBKE | 0.83388404 |
| 44 | RPS6KA5 | 0.81219415 |
| 45 | PTK2B | 0.80279951 |
| 46 | CAMKK2 | 0.79980058 |
| 47 | FLT3 | 0.79391806 |
| 48 | STK39 | 0.79355755 |
| 49 | OXSR1 | 0.77084157 |
| 50 | RPS6KA4 | 0.76576950 |
| 51 | DYRK3 | 0.74131130 |
| 52 | IKBKB | 0.73978012 |
| 53 | PBK | 0.73448950 |
| 54 | VRK2 | 0.73075113 |
| 55 | MAP3K14 | 0.72869015 |
| 56 | IRAK1 | 0.71358690 |
| 57 | SYK | 0.71354196 |
| 58 | CSNK1G3 | 0.68484161 |
| 59 | MYLK | 0.66057508 |
| 60 | STK16 | 0.64697872 |
| 61 | BRSK2 | 0.64691760 |
| 62 | EIF2AK3 | 0.63069638 |
| 63 | TBK1 | 0.62911775 |
| 64 | CSNK1G2 | 0.62445797 |
| 65 | CCNB1 | 0.60044138 |
| 66 | ITK | 0.58427717 |
| 67 | CSF1R | 0.57061072 |
| 68 | MKNK1 | 0.55052560 |
| 69 | IRAK4 | 0.54179314 |
| 70 | TGFBR1 | 0.52702832 |
| 71 | PINK1 | 0.52495965 |
| 72 | DAPK1 | 0.52293481 |
| 73 | HCK | 0.50540172 |
| 74 | KIT | 0.50058867 |
| 75 | WEE1 | 0.49929236 |
| 76 | CSNK1G1 | 0.48814618 |
| 77 | NLK | 0.47795845 |
| 78 | CDK8 | 0.46662566 |
| 79 | IGF1R | 0.46619663 |
| 80 | ADRBK1 | 0.46117741 |
| 81 | BTK | 0.46076487 |
| 82 | MAPKAPK3 | 0.44978744 |
| 83 | LYN | 0.44047567 |
| 84 | FGR | 0.43058641 |
| 85 | MATK | 0.42860760 |
| 86 | TGFBR2 | 0.42114886 |
| 87 | PIM1 | 0.41223186 |
| 88 | DYRK2 | 0.39561499 |
| 89 | MAP3K5 | 0.39521828 |
| 90 | EIF2AK2 | 0.37933363 |
| 91 | PHKG2 | 0.37663614 |
| 92 | PHKG1 | 0.37663614 |
| 93 | MUSK | 0.35225487 |
| 94 | LCK | 0.34251284 |
| 95 | CSNK1A1L | 0.34212364 |
| 96 | DAPK2 | 0.33800842 |
| 97 | PIK3CG | 0.33373421 |
| 98 | CSNK1D | 0.31755420 |
| 99 | CLK1 | 0.31292873 |
| 100 | PDK2 | 0.30819890 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.02519599 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.65984703 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 2.37553557 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 2.31892406 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.20528610 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.15593940 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.02790088 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.02420887 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.99402105 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 1.98844770 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.93577498 |
| 12 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.89190339 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.84871456 |
| 14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.75287835 |
| 15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.72328562 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.68396413 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.64510584 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.62652617 |
| 19 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.62517959 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.61728011 |
| 21 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.58235345 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56121295 |
| 23 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.55486376 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.51238745 |
| 25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.47957224 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.44400146 |
| 27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.42460433 |
| 28 | DNA replication_Homo sapiens_hsa03030 | 1.41867315 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.40483303 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.39781523 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.38074202 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.33789954 |
| 33 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.32905555 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.32014671 |
| 35 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.30212918 |
| 36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.29446060 |
| 37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.28476362 |
| 38 | Asthma_Homo sapiens_hsa05310 | 1.27145062 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.25661178 |
| 40 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.22451444 |
| 41 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.19912333 |
| 42 | Allograft rejection_Homo sapiens_hsa05330 | 1.18612657 |
| 43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.13403903 |
| 44 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.13146829 |
| 45 | Huntingtons disease_Homo sapiens_hsa05016 | 1.11003140 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.08440510 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.06365495 |
| 48 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.05335979 |
| 49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.04414281 |
| 50 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.03301474 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.03093470 |
| 52 | Spliceosome_Homo sapiens_hsa03040 | 1.03035583 |
| 53 | Peroxisome_Homo sapiens_hsa04146 | 0.96031282 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.95438097 |
| 55 | RNA transport_Homo sapiens_hsa03013 | 0.94792224 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.92977638 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91670315 |
| 58 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87891775 |
| 59 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.87454345 |
| 60 | Phototransduction_Homo sapiens_hsa04744 | 0.85662565 |
| 61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.85093514 |
| 62 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.84481439 |
| 63 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.83586559 |
| 64 | Alzheimers disease_Homo sapiens_hsa05010 | 0.82415732 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.77838574 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.77448963 |
| 67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.75890823 |
| 68 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.73959201 |
| 69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.73513776 |
| 70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71830595 |
| 71 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.70346269 |
| 72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.70235295 |
| 73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67343444 |
| 74 | Shigellosis_Homo sapiens_hsa05131 | 0.65404644 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64903184 |
| 76 | Carbon metabolism_Homo sapiens_hsa01200 | 0.63839873 |
| 77 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.61532358 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59876646 |
| 79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59106376 |
| 80 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58915205 |
| 81 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.58613587 |
| 82 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.57901041 |
| 83 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55242226 |
| 84 | Legionellosis_Homo sapiens_hsa05134 | 0.54993926 |
| 85 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53878676 |
| 86 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.53487306 |
| 87 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.51813915 |
| 88 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50933007 |
| 89 | Viral myocarditis_Homo sapiens_hsa05416 | 0.50858880 |
| 90 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.49753878 |
| 91 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.49628487 |
| 92 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.49468885 |
| 93 | Malaria_Homo sapiens_hsa05144 | 0.45924522 |
| 94 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.45902953 |
| 95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44879176 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42567785 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.41375555 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41368596 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40415776 |
| 100 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39736482 |

