Rank | Gene Set | Z-score |
---|---|---|
1 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.46587030 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.98436739 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.98436739 |
4 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.89037154 |
5 | melanin biosynthetic process (GO:0042438) | 3.83192440 |
6 | protein maturation by protein folding (GO:0022417) | 3.81103540 |
7 | COPI coating of Golgi vesicle (GO:0048205) | 3.69388614 |
8 | Golgi transport vesicle coating (GO:0048200) | 3.69388614 |
9 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.65843529 |
10 | regulation of superoxide anion generation (GO:0032928) | 3.60967166 |
11 | respiratory burst (GO:0045730) | 3.53279463 |
12 | neutrophil activation involved in immune response (GO:0002283) | 3.47819404 |
13 | cullin deneddylation (GO:0010388) | 3.41337814 |
14 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.39119604 |
15 | melanin metabolic process (GO:0006582) | 3.39066148 |
16 | immunoglobulin mediated immune response (GO:0016064) | 3.34152419 |
17 | protein deneddylation (GO:0000338) | 3.33936765 |
18 | pentose-phosphate shunt (GO:0006098) | 3.31872016 |
19 | NIK/NF-kappaB signaling (GO:0038061) | 3.30968053 |
20 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.25809213 |
21 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.25809213 |
22 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.24369189 |
23 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.20884394 |
24 | purine nucleotide salvage (GO:0032261) | 3.19945597 |
25 | secondary metabolite biosynthetic process (GO:0044550) | 3.16409265 |
26 | regulation of triglyceride catabolic process (GO:0010896) | 3.16264159 |
27 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.15442834 |
28 | aldehyde catabolic process (GO:0046185) | 3.15322136 |
29 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.13779719 |
30 | ATP synthesis coupled proton transport (GO:0015986) | 3.13170175 |
31 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.13170175 |
32 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.10268320 |
33 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.07754184 |
34 | regulation of cellular amine metabolic process (GO:0033238) | 3.07186060 |
35 | cellular extravasation (GO:0045123) | 3.06900961 |
36 | positive regulation of B cell differentiation (GO:0045579) | 3.04739746 |
37 | ribosomal small subunit assembly (GO:0000028) | 3.02862180 |
38 | positive regulation of ligase activity (GO:0051351) | 2.97756895 |
39 | pinocytosis (GO:0006907) | 2.96822120 |
40 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.95499830 |
41 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.93564859 |
42 | respiratory electron transport chain (GO:0022904) | 2.93160504 |
43 | phagosome maturation (GO:0090382) | 2.91621091 |
44 | regulation of RIG-I signaling pathway (GO:0039535) | 2.90645066 |
45 | GDP-mannose metabolic process (GO:0019673) | 2.89119734 |
46 | NADPH regeneration (GO:0006740) | 2.87694152 |
47 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.87343528 |
48 | electron transport chain (GO:0022900) | 2.86423681 |
49 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.86245692 |
50 | positive regulation of cell cycle arrest (GO:0071158) | 2.85131075 |
51 | regulation of superoxide metabolic process (GO:0090322) | 2.82528942 |
52 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.78148491 |
53 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.77028474 |
54 | pentose metabolic process (GO:0019321) | 2.75175831 |
55 | amyloid precursor protein catabolic process (GO:0042987) | 2.72934541 |
56 | B cell mediated immunity (GO:0019724) | 2.72834750 |
57 | positive regulation of antigen processing and presentation (GO:0002579) | 2.72008852 |
58 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.71034899 |
59 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.71034899 |
60 | glucose catabolic process (GO:0006007) | 2.70575388 |
61 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.70368141 |
62 | regulation of B cell differentiation (GO:0045577) | 2.70132943 |
63 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.69385148 |
64 | nucleoside salvage (GO:0043174) | 2.68641793 |
65 | L-methionine salvage (GO:0071267) | 2.66889488 |
66 | L-methionine biosynthetic process (GO:0071265) | 2.66889488 |
67 | amino acid salvage (GO:0043102) | 2.66889488 |
68 | viral mRNA export from host cell nucleus (GO:0046784) | 2.63567294 |
69 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.63550257 |
70 | pyrimidine nucleoside salvage (GO:0043097) | 2.62442359 |
71 | pyrimidine-containing compound salvage (GO:0008655) | 2.62442359 |
72 | proteasome assembly (GO:0043248) | 2.61771440 |
73 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.61358556 |
74 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.60764170 |
75 | L-phenylalanine catabolic process (GO:0006559) | 2.60764170 |
76 | galactose catabolic process (GO:0019388) | 2.58012538 |
77 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.56740666 |
78 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.56507125 |
79 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.56381145 |
80 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.56207737 |
81 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.55846162 |
82 | L-phenylalanine metabolic process (GO:0006558) | 2.55846162 |
83 | primary alcohol catabolic process (GO:0034310) | 2.55357324 |
84 | regulation of ligase activity (GO:0051340) | 2.55092786 |
85 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.54955729 |
86 | sequestering of actin monomers (GO:0042989) | 2.54894922 |
87 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.53644522 |
88 | NADH metabolic process (GO:0006734) | 2.53641216 |
89 | GMP metabolic process (GO:0046037) | 2.53511107 |
90 | regulation of response to interferon-gamma (GO:0060330) | 2.53184959 |
91 | purine-containing compound salvage (GO:0043101) | 2.53064093 |
92 | cofactor catabolic process (GO:0051187) | 2.52963928 |
93 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 2.50938607 |
94 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 2.50938607 |
95 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.50862403 |
96 | regulation of cholesterol esterification (GO:0010872) | 2.50358808 |
97 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.49376908 |
98 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.49170778 |
99 | positive regulation of interferon-alpha production (GO:0032727) | 2.48646380 |
100 | protein complex biogenesis (GO:0070271) | 2.48057587 |
101 | myeloid cell activation involved in immune response (GO:0002275) | 2.46888180 |
102 | alpha-linolenic acid metabolic process (GO:0036109) | 2.46283091 |
103 | protein targeting to mitochondrion (GO:0006626) | 2.44992980 |
104 | negative regulation of B cell apoptotic process (GO:0002903) | 2.44501163 |
105 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.44264821 |
106 | signal transduction in response to DNA damage (GO:0042770) | 2.42686034 |
107 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.42597098 |
108 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.42597098 |
109 | leukocyte mediated cytotoxicity (GO:0001909) | 2.42474836 |
110 | S-adenosylmethionine metabolic process (GO:0046500) | 2.42466257 |
111 | antigen processing and presentation of exogenous peptide antigen (GO:0002478) | 2.42315499 |
112 | mast cell activation (GO:0045576) | 2.42230768 |
113 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.42041712 |
114 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.42041712 |
115 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.42006904 |
116 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.41485340 |
117 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.40321541 |
118 | establishment of viral latency (GO:0019043) | 2.39854315 |
119 | positive regulation by symbiont of host defense response (GO:0052509) | 2.39396827 |
120 | modulation by symbiont of host defense response (GO:0052031) | 2.39396827 |
121 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.39396827 |
122 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.39396827 |
123 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.39396827 |
124 | modulation by symbiont of host immune response (GO:0052553) | 2.39396827 |
125 | negative regulation of protein ubiquitination (GO:0031397) | 2.38883093 |
126 | neutrophil activation (GO:0042119) | 2.37602048 |
127 | regulation of cell cycle arrest (GO:0071156) | 2.37520172 |
128 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.37209085 |
129 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.37209085 |
130 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.37209085 |
131 | negative regulation of protein modification by small protein conjugation or removal (GO:1903321) | 2.36837797 |
132 | antigen processing and presentation of exogenous antigen (GO:0019884) | 2.36815308 |
133 | GTP biosynthetic process (GO:0006183) | 2.35935988 |
134 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.35832817 |
135 | xenobiotic catabolic process (GO:0042178) | 2.34289676 |
136 | regulation of interferon-alpha production (GO:0032647) | 2.34152729 |
137 | regulation of antigen processing and presentation (GO:0002577) | 2.33284013 |
138 | regulation of cholesterol storage (GO:0010885) | 2.33198520 |
139 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.32603466 |
140 | actin nucleation (GO:0045010) | 2.31942948 |
141 | leukocyte degranulation (GO:0043299) | 2.31254333 |
142 | negative regulation of ligase activity (GO:0051352) | 2.31123440 |
143 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.31123440 |
144 | aromatic amino acid family catabolic process (GO:0009074) | 2.30579125 |
145 | DNA deamination (GO:0045006) | 2.29713467 |
146 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.28675901 |
147 | leukocyte aggregation (GO:0070486) | 2.27290684 |
148 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.26586565 |
149 | response to thyroid hormone (GO:0097066) | 2.26496478 |
150 | T cell migration (GO:0072678) | 2.26436417 |
151 | macrophage activation involved in immune response (GO:0002281) | 2.25779539 |
152 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.25597158 |
153 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.25233248 |
154 | natural killer cell mediated immunity (GO:0002228) | 2.25233248 |
155 | negative regulation of phagocytosis (GO:0050765) | 2.25078914 |
156 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.24881656 |
157 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.24881656 |
158 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.23677176 |
159 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.22632197 |
160 | oxaloacetate metabolic process (GO:0006107) | 2.22531044 |
161 | rRNA modification (GO:0000154) | 2.22298401 |
162 | germinal center formation (GO:0002467) | 2.22125498 |
163 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.21166936 |
164 | heme metabolic process (GO:0042168) | 2.20153570 |
165 | hepatocyte apoptotic process (GO:0097284) | 2.19712451 |
166 | response to interferon-beta (GO:0035456) | 2.17788637 |
167 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.17274852 |
168 | sulfur amino acid catabolic process (GO:0000098) | 2.16831709 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.83914949 |
2 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.33676035 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.20883146 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.00377900 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.99891955 |
6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.88082110 |
7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.82630613 |
8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.80400688 |
9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.69270073 |
10 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.59108631 |
11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.54962568 |
12 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.51945251 |
13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.51265892 |
14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.49791869 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.46608536 |
16 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.43828576 |
17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.29262015 |
18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.22497369 |
19 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.21351348 |
20 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.19584967 |
21 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.16770658 |
22 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.14090736 |
23 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.13424768 |
24 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.07227100 |
25 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.05800849 |
26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.05471224 |
27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.05310167 |
28 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.91350479 |
29 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.88435113 |
30 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.88349749 |
31 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.87188361 |
32 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.85345146 |
33 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.83157221 |
34 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74797645 |
35 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.74101282 |
36 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.71462245 |
37 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.68366741 |
38 | GATA1_22025678_ChIP-Seq_K562_Human | 1.67681661 |
39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.65818796 |
40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.63613177 |
41 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61528824 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55844958 |
43 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.53211077 |
44 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.52040022 |
45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.51475258 |
46 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.49772532 |
47 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48484633 |
48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.48068636 |
49 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46528131 |
50 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.46295160 |
51 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.44199897 |
52 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.42561015 |
53 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37619718 |
54 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.37614118 |
55 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.37411457 |
56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.36157250 |
57 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33419399 |
58 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.33018083 |
59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31992654 |
60 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.31370043 |
61 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.30720792 |
62 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.30330833 |
63 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.29544903 |
64 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.29288017 |
65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.28958813 |
66 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28745390 |
67 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.28131354 |
68 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.27495897 |
69 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.25846571 |
70 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.25837084 |
71 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.25805913 |
72 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25620574 |
73 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.25537601 |
74 | MYB_26560356_Chip-Seq_TH2_Human | 1.25190420 |
75 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.25072961 |
76 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.23131329 |
77 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.22629545 |
78 | MYC_22102868_ChIP-Seq_BL_Human | 1.21764128 |
79 | MAF_26560356_Chip-Seq_TH1_Human | 1.21544314 |
80 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.21516764 |
81 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.20611145 |
82 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.19384950 |
83 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19207890 |
84 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19089204 |
85 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.18757228 |
86 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18630876 |
87 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.17951710 |
88 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.17894806 |
89 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.15627064 |
90 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.15423143 |
91 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.14293168 |
92 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.14046727 |
93 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.13452091 |
94 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.13288647 |
95 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.12914288 |
96 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.12153768 |
97 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.11348565 |
98 | SPI1_23127762_ChIP-Seq_K562_Human | 1.11290881 |
99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.10429414 |
100 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.10252851 |
101 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.10049394 |
102 | MAF_26560356_Chip-Seq_TH2_Human | 1.09844765 |
103 | MYB_26560356_Chip-Seq_TH1_Human | 1.09231328 |
104 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.08702355 |
105 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.08554148 |
106 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.08551733 |
107 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.07942390 |
108 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07610004 |
109 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.07303142 |
110 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06233184 |
111 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05819325 |
112 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.05334422 |
113 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.04801902 |
114 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04551860 |
115 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03353527 |
116 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.03165749 |
117 | UTX_26944678_Chip-Seq_JUKART_Human | 1.02945146 |
118 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.02298874 |
119 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02287856 |
120 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.02129375 |
121 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01197958 |
122 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.99759932 |
123 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.99127431 |
124 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.98853957 |
125 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.98796589 |
126 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.98698885 |
127 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.98625399 |
128 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.98015159 |
129 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97164018 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000372_irregular_coat_pigmentation | 4.16624929 |
2 | MP0001835_abnormal_antigen_presentation | 3.87886795 |
3 | MP0003191_abnormal_cellular_cholesterol | 3.49003838 |
4 | MP0003436_decreased_susceptibility_to | 3.28645510 |
5 | MP0002877_abnormal_melanocyte_morpholog | 3.20589217 |
6 | MP0005408_hypopigmentation | 3.14518582 |
7 | MP0009840_abnormal_foam_cell | 3.05960757 |
8 | MP0009785_altered_susceptibility_to | 2.99156113 |
9 | MP0005671_abnormal_response_to | 2.90689866 |
10 | MP0000015_abnormal_ear_pigmentation | 2.86598813 |
11 | MP0006082_CNS_inflammation | 2.83340659 |
12 | MP0003806_abnormal_nucleotide_metabolis | 2.53990709 |
13 | MP0000685_abnormal_immune_system | 2.44276833 |
14 | MP0005025_abnormal_response_to | 2.43866006 |
15 | MP0005000_abnormal_immune_tolerance | 2.43106370 |
16 | MP0002419_abnormal_innate_immunity | 2.42674408 |
17 | MP0002139_abnormal_hepatobiliary_system | 2.39756207 |
18 | MP0005171_absent_coat_pigmentation | 2.38494067 |
19 | MP0005464_abnormal_platelet_physiology | 2.35787402 |
20 | MP0005058_abnormal_lysosome_morphology | 2.33173616 |
21 | MP0002148_abnormal_hypersensitivity_rea | 2.27833280 |
22 | MP0001800_abnormal_humoral_immune | 2.25952043 |
23 | MP0003724_increased_susceptibility_to | 2.23046938 |
24 | MP0002452_abnormal_antigen_presenting | 2.19103731 |
25 | MP0005360_urolithiasis | 2.18324356 |
26 | MP0005365_abnormal_bile_salt | 2.18192278 |
27 | MP0002132_abnormal_respiratory_system | 2.15824478 |
28 | MP0002723_abnormal_immune_serum | 2.07223535 |
29 | MP0003186_abnormal_redox_activity | 1.96783100 |
30 | MP0004381_abnormal_hair_follicle | 1.96345035 |
31 | MP0003656_abnormal_erythrocyte_physiolo | 1.96238663 |
32 | MP0001819_abnormal_immune_cell | 1.95298181 |
33 | MP0002420_abnormal_adaptive_immunity | 1.93887075 |
34 | MP0009333_abnormal_splenocyte_physiolog | 1.93792666 |
35 | MP0002095_abnormal_skin_pigmentation | 1.93570550 |
36 | MP0001853_heart_inflammation | 1.82648339 |
37 | MP0005085_abnormal_gallbladder_physiolo | 1.81288938 |
38 | MP0001790_abnormal_immune_system | 1.77235407 |
39 | MP0005387_immune_system_phenotype | 1.77235407 |
40 | MP0010329_abnormal_lipoprotein_level | 1.76145572 |
41 | MP0008875_abnormal_xenobiotic_pharmacok | 1.75883608 |
42 | MP0001764_abnormal_homeostasis | 1.74115248 |
43 | MP0005397_hematopoietic_system_phenotyp | 1.72109850 |
44 | MP0001545_abnormal_hematopoietic_system | 1.72109850 |
45 | MP0001845_abnormal_inflammatory_respons | 1.69923782 |
46 | MP0008469_abnormal_protein_level | 1.68596440 |
47 | MP0003303_peritoneal_inflammation | 1.68553432 |
48 | MP0002398_abnormal_bone_marrow | 1.67831536 |
49 | MP0000371_diluted_coat_color | 1.67694820 |
50 | MP0005451_abnormal_body_composition | 1.64743803 |
51 | MP0000716_abnormal_immune_system | 1.59930403 |
52 | MP0001533_abnormal_skeleton_physiology | 1.58637064 |
53 | MP0002405_respiratory_system_inflammati | 1.56452224 |
54 | MP0000689_abnormal_spleen_morphology | 1.51534346 |
55 | MP0004510_myositis | 1.44039298 |
56 | MP0002429_abnormal_blood_cell | 1.42734865 |
57 | MP0002722_abnormal_immune_system | 1.42204993 |
58 | MP0003763_abnormal_thymus_physiology | 1.41121622 |
59 | MP0004947_skin_inflammation | 1.40674360 |
60 | MP0000749_muscle_degeneration | 1.40590616 |
61 | MP0002396_abnormal_hematopoietic_system | 1.37886665 |
62 | MP0005174_abnormal_tail_pigmentation | 1.37053917 |
63 | MP0000609_abnormal_liver_physiology | 1.36052828 |
64 | MP0000604_amyloidosis | 1.34033659 |
65 | MP0010155_abnormal_intestine_physiology | 1.28487802 |
66 | MP0003172_abnormal_lysosome_physiology | 1.25119712 |
67 | MP0009764_decreased_sensitivity_to | 1.24374923 |
68 | MP0006036_abnormal_mitochondrial_physio | 1.23932144 |
69 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.18318035 |
70 | MP0008260_abnormal_autophagy | 1.18291823 |
71 | MP0005165_increased_susceptibility_to | 1.16349753 |
72 | MP0000343_altered_response_to | 1.16160695 |
73 | MP0002876_abnormal_thyroid_physiology | 1.15883535 |
74 | MP0000358_abnormal_cell_content/ | 1.15031134 |
75 | MP0005319_abnormal_enzyme/_coenzyme | 1.14380177 |
76 | MP0009763_increased_sensitivity_to | 1.12783850 |
77 | MP0004233_abnormal_muscle_weight | 1.12614521 |
78 | MP0004147_increased_porphyrin_level | 1.09893758 |
79 | MP0000858_altered_metastatic_potential | 1.09111886 |
80 | MP0003183_abnormal_peptide_metabolism | 1.08870311 |
81 | MP0002166_altered_tumor_susceptibility | 1.07143418 |
82 | MP0005310_abnormal_salivary_gland | 1.06922945 |
83 | MP0005083_abnormal_biliary_tract | 1.06117220 |
84 | MP0000465_gastrointestinal_hemorrhage | 1.05749115 |
85 | MP0001186_pigmentation_phenotype | 1.02446619 |
86 | MP0002332_abnormal_exercise_endurance | 1.02126134 |
87 | MP0002118_abnormal_lipid_homeostasis | 1.01798615 |
88 | MP0002006_tumorigenesis | 1.00986336 |
89 | MP0003329_amyloid_beta_deposits | 1.00890443 |
90 | MP0005332_abnormal_amino_acid | 0.98905653 |
91 | MP0003075_altered_response_to | 0.98839068 |
92 | MP0003828_pulmonary_edema | 0.97989174 |
93 | MP0000747_muscle_weakness | 0.96351232 |
94 | MP0002933_joint_inflammation | 0.94173097 |
95 | MP0000598_abnormal_liver_morphology | 0.93659501 |
96 | MP0002075_abnormal_coat/hair_pigmentati | 0.92742158 |
97 | MP0004782_abnormal_surfactant_physiolog | 0.92736227 |
98 | MP0003950_abnormal_plasma_membrane | 0.90671256 |
99 | MP0006035_abnormal_mitochondrial_morpho | 0.89695636 |
100 | MP0001905_abnormal_dopamine_level | 0.89328692 |
101 | MP0003011_delayed_dark_adaptation | 0.88044924 |
102 | MP0005075_abnormal_melanosome_morpholog | 0.87293483 |
103 | MP0003866_abnormal_defecation | 0.86544366 |
104 | MP0005164_abnormal_response_to | 0.84307941 |
105 | MP0009643_abnormal_urine_homeostasis | 0.83907888 |
106 | MP0003646_muscle_fatigue | 0.83062331 |
107 | MP0000750_abnormal_muscle_regeneration | 0.82148158 |
108 | MP0008007_abnormal_cellular_replicative | 0.81962228 |
109 | MP0008873_increased_physiological_sensi | 0.81885451 |
110 | MP0001873_stomach_inflammation | 0.81784045 |
111 | MP0000703_abnormal_thymus_morphology | 0.81674477 |
112 | MP0001727_abnormal_embryo_implantation | 0.79969677 |
113 | MP0003448_altered_tumor_morphology | 0.78591886 |
114 | MP0005330_cardiomyopathy | 0.76695785 |
115 | MP0005166_decreased_susceptibility_to | 0.75756114 |
116 | MP0000249_abnormal_blood_vessel | 0.75634607 |
117 | MP0009765_abnormal_xenobiotic_induced | 0.75423949 |
118 | MP0000920_abnormal_myelination | 0.75109578 |
119 | MP0003300_gastrointestinal_ulcer | 0.73276545 |
120 | MP0003221_abnormal_cardiomyocyte_apopto | 0.72945040 |
121 | MP0001666_abnormal_nutrient_absorption | 0.71643594 |
122 | MP0001542_abnormal_bone_strength | 0.71618544 |
123 | MP0004883_abnormal_blood_vessel | 0.71403636 |
124 | MP0002019_abnormal_tumor_incidence | 0.70613094 |
125 | MP0009278_abnormal_bone_marrow | 0.70037355 |
126 | MP0002090_abnormal_vision | 0.69632603 |
127 | MP0003786_premature_aging | 0.68940027 |
128 | MP0009642_abnormal_blood_homeostasis | 0.68264075 |
129 | MP0001851_eye_inflammation | 0.67111192 |
130 | MP0005376_homeostasis/metabolism_phenot | 0.66560409 |
131 | MP0002138_abnormal_hepatobiliary_system | 0.66014987 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.13233560 |
2 | Recurrent abscess formation (HP:0002722) | 4.08917193 |
3 | Recurrent bacterial skin infections (HP:0005406) | 3.87826670 |
4 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.86557402 |
5 | Eczematoid dermatitis (HP:0000976) | 3.86532073 |
6 | Petechiae (HP:0000967) | 3.60420978 |
7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.57880811 |
8 | Myositis (HP:0100614) | 3.48506322 |
9 | Acute necrotizing encephalopathy (HP:0006965) | 3.44112494 |
10 | Systemic lupus erythematosus (HP:0002725) | 3.40708326 |
11 | Vacuolated lymphocytes (HP:0001922) | 3.35349406 |
12 | Increased cerebral lipofuscin (HP:0011813) | 3.20447617 |
13 | Abnormality of macrophages (HP:0004311) | 3.17056244 |
14 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.15884882 |
15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.05306500 |
16 | Hypokinesia (HP:0002375) | 3.02728697 |
17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.98914281 |
18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.98914281 |
19 | Thrombocytosis (HP:0001894) | 2.98361294 |
20 | Progressive macrocephaly (HP:0004481) | 2.93955986 |
21 | Acute encephalopathy (HP:0006846) | 2.88453718 |
22 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.85911816 |
23 | Purpura (HP:0000979) | 2.85705338 |
24 | Orchitis (HP:0100796) | 2.80905001 |
25 | Recurrent skin infections (HP:0001581) | 2.79436127 |
26 | Ocular albinism (HP:0001107) | 2.76037153 |
27 | Amyloidosis (HP:0011034) | 2.72509877 |
28 | Type I transferrin isoform profile (HP:0003642) | 2.71868837 |
29 | Hepatosplenomegaly (HP:0001433) | 2.66501962 |
30 | Patchy hypopigmentation of hair (HP:0011365) | 2.65026517 |
31 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.60987116 |
32 | Hepatic necrosis (HP:0002605) | 2.60404363 |
33 | Hypobetalipoproteinemia (HP:0003563) | 2.58028576 |
34 | Autoimmune thrombocytopenia (HP:0001973) | 2.56735593 |
35 | Hyperlipoproteinemia (HP:0010980) | 2.55470890 |
36 | Hepatocellular necrosis (HP:0001404) | 2.54462989 |
37 | Prolonged partial thromboplastin time (HP:0003645) | 2.53573893 |
38 | Exercise intolerance (HP:0003546) | 2.52030617 |
39 | Complement deficiency (HP:0004431) | 2.51254296 |
40 | Optic neuritis (HP:0100653) | 2.50631868 |
41 | Retrobulbar optic neuritis (HP:0100654) | 2.50631868 |
42 | Vertebral compression fractures (HP:0002953) | 2.50219015 |
43 | Xanthomatosis (HP:0000991) | 2.43535723 |
44 | Abnormality of glycolysis (HP:0004366) | 2.41391554 |
45 | Increased serum pyruvate (HP:0003542) | 2.41391554 |
46 | Rhabdomyolysis (HP:0003201) | 2.39753024 |
47 | Axonal loss (HP:0003447) | 2.39720886 |
48 | Abnormal platelet function (HP:0011869) | 2.38517869 |
49 | Impaired platelet aggregation (HP:0003540) | 2.38517869 |
50 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.37865646 |
51 | Recurrent fungal infections (HP:0002841) | 2.37435362 |
52 | Epistaxis (HP:0000421) | 2.36073723 |
53 | Lactic acidosis (HP:0003128) | 2.33446400 |
54 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.32379185 |
55 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.32379185 |
56 | Abnormality of glycolipid metabolism (HP:0010969) | 2.32379185 |
57 | Mediastinal lymphadenopathy (HP:0100721) | 2.31720873 |
58 | Agnosia (HP:0010524) | 2.29485647 |
59 | Deep venous thrombosis (HP:0002625) | 2.29321652 |
60 | Iris hypopigmentation (HP:0007730) | 2.28818088 |
61 | Pustule (HP:0200039) | 2.27587116 |
62 | Leukocytosis (HP:0001974) | 2.27290820 |
63 | Increased IgM level (HP:0003496) | 2.26796155 |
64 | White forelock (HP:0002211) | 2.26094238 |
65 | Vasculitis (HP:0002633) | 2.25704641 |
66 | Ragged-red muscle fibers (HP:0003200) | 2.25559353 |
67 | Cerebral edema (HP:0002181) | 2.24364817 |
68 | Albinism (HP:0001022) | 2.23796464 |
69 | Urticaria (HP:0001025) | 2.22986893 |
70 | Gingival bleeding (HP:0000225) | 2.21336812 |
71 | Keratoconjunctivitis sicca (HP:0001097) | 2.20869265 |
72 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.20857680 |
73 | Gastrointestinal stroma tumor (HP:0100723) | 2.20343856 |
74 | Reduced antithrombin III activity (HP:0001976) | 2.19835734 |
75 | Abnormal pupillary function (HP:0007686) | 2.19111267 |
76 | Abnormal protein glycosylation (HP:0012346) | 2.18700827 |
77 | Abnormal glycosylation (HP:0012345) | 2.18700827 |
78 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.18700827 |
79 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.18700827 |
80 | Glomerulonephritis (HP:0000099) | 2.18485382 |
81 | Joint hemorrhage (HP:0005261) | 2.17886949 |
82 | Cutaneous melanoma (HP:0012056) | 2.17742768 |
83 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.17551840 |
84 | Combined immunodeficiency (HP:0005387) | 2.15184460 |
85 | 3-Methylglutaconic aciduria (HP:0003535) | 2.13252558 |
86 | Increased serum lactate (HP:0002151) | 2.13198433 |
87 | Heterochromia iridis (HP:0001100) | 2.12837272 |
88 | Abnormality of complement system (HP:0005339) | 2.12125387 |
89 | Respiratory failure (HP:0002878) | 2.11760882 |
90 | Aplastic anemia (HP:0001915) | 2.11586350 |
91 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.10144177 |
92 | Prostate neoplasm (HP:0100787) | 2.09501101 |
93 | Loss of speech (HP:0002371) | 2.09279924 |
94 | Emotional lability (HP:0000712) | 2.08779490 |
95 | Muscle fibrillation (HP:0010546) | 2.08595430 |
96 | Fatigue (HP:0012378) | 2.07928522 |
97 | Rough bone trabeculation (HP:0100670) | 2.07480607 |
98 | Abnormality of the anterior horn cell (HP:0006802) | 2.07361170 |
99 | Degeneration of anterior horn cells (HP:0002398) | 2.07361170 |
100 | Abnormal gallbladder physiology (HP:0012438) | 2.06780339 |
101 | Cholecystitis (HP:0001082) | 2.06780339 |
102 | Renal Fanconi syndrome (HP:0001994) | 2.06374542 |
103 | Keratoconjunctivitis (HP:0001096) | 2.06241309 |
104 | Poor head control (HP:0002421) | 2.06033540 |
105 | Progressive neurologic deterioration (HP:0002344) | 2.06015756 |
106 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.05819204 |
107 | Distal lower limb muscle weakness (HP:0009053) | 2.05734416 |
108 | Agammaglobulinemia (HP:0004432) | 2.04852873 |
109 | Hypertensive crisis (HP:0100735) | 2.04636417 |
110 | IgM deficiency (HP:0002850) | 2.04043715 |
111 | Prolonged bleeding time (HP:0003010) | 2.03645978 |
112 | Cholelithiasis (HP:0001081) | 2.03490487 |
113 | Opisthotonus (HP:0002179) | 2.03223779 |
114 | Prolonged neonatal jaundice (HP:0006579) | 2.02672969 |
115 | Chronic obstructive pulmonary disease (HP:0006510) | 2.01225299 |
116 | Obstructive lung disease (HP:0006536) | 2.01225299 |
117 | Stomatitis (HP:0010280) | 2.00742128 |
118 | Severe combined immunodeficiency (HP:0004430) | 1.99224720 |
119 | Abnormality of eosinophils (HP:0001879) | 1.98850384 |
120 | Hypergammaglobulinemia (HP:0010702) | 1.97962673 |
121 | Exertional dyspnea (HP:0002875) | 1.97883772 |
122 | Myocardial infarction (HP:0001658) | 1.97695947 |
123 | Recurrent viral infections (HP:0004429) | 1.97538302 |
124 | Respiratory difficulties (HP:0002880) | 1.97431337 |
125 | Meningitis (HP:0001287) | 1.97327361 |
126 | Spastic paraparesis (HP:0002313) | 1.96360296 |
127 | Interstitial pulmonary disease (HP:0006530) | 1.96136777 |
128 | Panhypogammaglobulinemia (HP:0003139) | 1.96049409 |
129 | Generalized hypopigmentation (HP:0007513) | 1.95953815 |
130 | Microvesicular hepatic steatosis (HP:0001414) | 1.95480598 |
131 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.95278019 |
132 | Mitochondrial inheritance (HP:0001427) | 1.94178097 |
133 | Premature graying of hair (HP:0002216) | 1.92603945 |
134 | Increased muscle lipid content (HP:0009058) | 1.92462244 |
135 | Tongue fasciculations (HP:0001308) | 1.92186174 |
136 | Acute hepatic failure (HP:0006554) | 1.92156599 |
137 | Increased hepatocellular lipid droplets (HP:0006565) | 1.90976040 |
138 | Increased serum ferritin (HP:0003281) | 1.90484422 |
139 | Nausea (HP:0002018) | 1.89884200 |
140 | Encephalitis (HP:0002383) | 1.89756979 |
141 | Gastrointestinal infarctions (HP:0005244) | 1.89663536 |
142 | Lipid accumulation in hepatocytes (HP:0006561) | 1.89619220 |
143 | Hyperammonemia (HP:0001987) | 1.87886659 |
144 | Muscle fiber atrophy (HP:0100295) | 1.87378118 |
145 | Nonimmune hydrops fetalis (HP:0001790) | 1.87093720 |
146 | Increased CSF lactate (HP:0002490) | 1.86427734 |
147 | Dysostosis multiplex (HP:0000943) | 1.86259841 |
148 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 1.85914575 |
149 | Nemaline bodies (HP:0003798) | 1.85732852 |
150 | Arterial thrombosis (HP:0004420) | 1.85383037 |
151 | Cellulitis (HP:0100658) | 1.85100365 |
152 | IgG deficiency (HP:0004315) | 1.84504108 |
153 | Chronic otitis media (HP:0000389) | 1.84395282 |
154 | Recurrent cutaneous fungal infections (HP:0011370) | 1.84155852 |
155 | Type 2 muscle fiber atrophy (HP:0003554) | 1.83921959 |
156 | Orthostatic hypotension (HP:0001278) | 1.82165750 |
157 | Myoglobinuria (HP:0002913) | 1.81416025 |
158 | Episodic fever (HP:0001954) | 1.80514604 |
159 | Abnormal gallbladder morphology (HP:0012437) | 1.74303958 |
160 | Generalized aminoaciduria (HP:0002909) | 1.71241309 |
161 | Amniotic constriction ring (HP:0009775) | 1.70962257 |
162 | Abnormality of placental membranes (HP:0011409) | 1.70962257 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BLK | 3.26461750 |
2 | PIK3CG | 3.19156233 |
3 | VRK2 | 3.08419453 |
4 | MAP4K1 | 3.08041889 |
5 | KIT | 2.88375813 |
6 | TBK1 | 2.66303489 |
7 | SCYL2 | 2.64110119 |
8 | LIMK1 | 2.63130512 |
9 | PIM2 | 2.53681510 |
10 | IRAK4 | 2.52294680 |
11 | ZAP70 | 2.48774997 |
12 | TESK2 | 2.38572559 |
13 | TXK | 2.24072703 |
14 | TYK2 | 2.18996640 |
15 | BCKDK | 2.17784100 |
16 | MAP3K14 | 2.08244722 |
17 | BUB1 | 2.04811831 |
18 | PBK | 2.04179083 |
19 | RIPK4 | 1.95771725 |
20 | NME2 | 1.85472951 |
21 | MAP3K12 | 1.83713300 |
22 | CSF1R | 1.80953408 |
23 | KDR | 1.78924767 |
24 | ARAF | 1.75789261 |
25 | ERN1 | 1.68516881 |
26 | SYK | 1.64947901 |
27 | CCNB1 | 1.62886088 |
28 | IRAK3 | 1.61254723 |
29 | MAP2K3 | 1.52482083 |
30 | IKBKE | 1.50523327 |
31 | RPS6KA4 | 1.48809942 |
32 | NEK9 | 1.39018904 |
33 | FLT3 | 1.37865015 |
34 | STK16 | 1.37770305 |
35 | EIF2AK1 | 1.37511380 |
36 | GRK6 | 1.34502333 |
37 | IKBKB | 1.34238140 |
38 | TRIB3 | 1.28829220 |
39 | BTK | 1.25251176 |
40 | MATK | 1.23198450 |
41 | MYLK | 1.21348328 |
42 | PDK2 | 1.18769749 |
43 | TSSK6 | 1.17470850 |
44 | JAK3 | 1.17427016 |
45 | TEC | 1.17180645 |
46 | DAPK3 | 1.13457517 |
47 | MARK3 | 1.11146046 |
48 | TLK1 | 1.07595193 |
49 | SRPK1 | 1.04610090 |
50 | DAPK1 | 1.04399483 |
51 | WEE1 | 1.04108018 |
52 | CASK | 1.03899833 |
53 | CAMKK2 | 1.03512528 |
54 | EPHA2 | 1.02954102 |
55 | SIK2 | 0.99508384 |
56 | ILK | 0.97597694 |
57 | PIM1 | 0.91081480 |
58 | JAK1 | 0.90096363 |
59 | LCK | 0.89643420 |
60 | ITK | 0.87289745 |
61 | BRAF | 0.87064661 |
62 | TAOK2 | 0.86748871 |
63 | ABL2 | 0.86210690 |
64 | MAP3K10 | 0.85946957 |
65 | NEK1 | 0.85089658 |
66 | MOS | 0.84125434 |
67 | LRRK2 | 0.83893433 |
68 | LYN | 0.83068991 |
69 | SIK3 | 0.82229654 |
70 | FGFR4 | 0.80235670 |
71 | EIF2AK3 | 0.78977309 |
72 | CLK1 | 0.78408991 |
73 | MAPKAPK3 | 0.77995501 |
74 | MUSK | 0.76021625 |
75 | EPHB1 | 0.75972969 |
76 | RPS6KB2 | 0.74289647 |
77 | TESK1 | 0.73768100 |
78 | JAK2 | 0.71174948 |
79 | BRSK2 | 0.68270614 |
80 | DAPK2 | 0.67603620 |
81 | STK10 | 0.66836691 |
82 | FGR | 0.66187657 |
83 | PRKG2 | 0.65190572 |
84 | MAPK4 | 0.64762763 |
85 | MAPK12 | 0.64527893 |
86 | CHUK | 0.64267865 |
87 | MAP2K6 | 0.64132077 |
88 | PRKCD | 0.63537432 |
89 | RAF1 | 0.63340897 |
90 | MAP4K2 | 0.62282281 |
91 | CDK19 | 0.62031775 |
92 | MAPKAPK2 | 0.61458569 |
93 | CSK | 0.60314014 |
94 | MST4 | 0.58703239 |
95 | MAP3K11 | 0.57247661 |
96 | RPS6KA6 | 0.56483176 |
97 | CDK8 | 0.54529870 |
98 | FES | 0.53509768 |
99 | GRK7 | 0.53312638 |
100 | LMTK2 | 0.53140294 |
101 | MAP3K1 | 0.51108509 |
102 | MAP2K4 | 0.50616863 |
103 | CAMK2G | 0.49910523 |
104 | PRKCI | 0.49026088 |
105 | PAK1 | 0.48694468 |
106 | PDPK1 | 0.48374371 |
107 | ADRBK2 | 0.47888909 |
108 | TAOK3 | 0.47357015 |
109 | CAMK2D | 0.47040231 |
110 | HCK | 0.44980938 |
111 | PAK6 | 0.43609376 |
112 | CDK7 | 0.43171142 |
113 | SIK1 | 0.42178389 |
114 | MAP3K5 | 0.41324703 |
115 | MAPK7 | 0.40724428 |
116 | PAK4 | 0.40636882 |
117 | TNK2 | 0.40480536 |
118 | MAPK11 | 0.40363130 |
119 | MINK1 | 0.39982189 |
120 | PTK2B | 0.38992894 |
121 | TGFBR2 | 0.38456010 |
122 | MAP2K1 | 0.38100657 |
123 | NME1 | 0.37445535 |
124 | BRSK1 | 0.36602664 |
125 | PHKG1 | 0.36533715 |
126 | PHKG2 | 0.36533715 |
127 | RPS6KC1 | 0.36449283 |
128 | RPS6KL1 | 0.36449283 |
129 | DYRK3 | 0.35407317 |
130 | CSNK1G3 | 0.34682251 |
131 | PDK1 | 0.34623127 |
132 | GRK5 | 0.34396753 |
133 | FER | 0.33722318 |
134 | BMPR2 | 0.33649310 |
135 | MAP2K7 | 0.33365459 |
136 | MAP3K3 | 0.32924655 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 3.34315599 |
2 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.78999272 |
3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.62093719 |
4 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.36540081 |
5 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.02331793 |
6 | Alzheimers disease_Homo sapiens_hsa05010 | 1.93529717 |
7 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.89690242 |
8 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.89183046 |
9 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.86273442 |
10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.85095306 |
11 | Ribosome_Homo sapiens_hsa03010 | 1.81922439 |
12 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.80717354 |
13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.78980855 |
14 | Leishmaniasis_Homo sapiens_hsa05140 | 1.73934009 |
15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.70470775 |
16 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.61217018 |
17 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.59324061 |
18 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.58771160 |
19 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.52436297 |
20 | RNA polymerase_Homo sapiens_hsa03020 | 1.48691932 |
21 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.47867420 |
22 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.40911473 |
23 | Peroxisome_Homo sapiens_hsa04146 | 1.39171592 |
24 | Lysosome_Homo sapiens_hsa04142 | 1.34655331 |
25 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.34274592 |
26 | Galactose metabolism_Homo sapiens_hsa00052 | 1.33842414 |
27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.33586381 |
28 | Histidine metabolism_Homo sapiens_hsa00340 | 1.31474101 |
29 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.30713593 |
30 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29294965 |
31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.28638725 |
32 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.27293538 |
33 | Pertussis_Homo sapiens_hsa05133 | 1.25834549 |
34 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.24430426 |
35 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.21615352 |
36 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.21557676 |
37 | Legionellosis_Homo sapiens_hsa05134 | 1.21356481 |
38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21108041 |
39 | Allograft rejection_Homo sapiens_hsa05330 | 1.18103741 |
40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16146167 |
41 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.14966721 |
42 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.14486574 |
43 | Other glycan degradation_Homo sapiens_hsa00511 | 1.14164263 |
44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.13989417 |
45 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.11646507 |
46 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.11323142 |
47 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.10954220 |
48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.08508005 |
49 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.07797577 |
50 | Phagosome_Homo sapiens_hsa04145 | 1.07493541 |
51 | Measles_Homo sapiens_hsa05162 | 1.06502523 |
52 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.06068479 |
53 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.06050344 |
54 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.05260652 |
55 | Carbon metabolism_Homo sapiens_hsa01200 | 1.04946252 |
56 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.04868556 |
57 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.03204037 |
58 | Tuberculosis_Homo sapiens_hsa05152 | 1.02555158 |
59 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.00230058 |
60 | Viral myocarditis_Homo sapiens_hsa05416 | 1.00146384 |
61 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.98864453 |
62 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.98367317 |
63 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.96840189 |
64 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.95912283 |
65 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.95622802 |
66 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.95292973 |
67 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.95250307 |
68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.94505481 |
69 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.93801213 |
70 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.92879741 |
71 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.92334029 |
72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.92043665 |
73 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.92009057 |
74 | Parkinsons disease_Homo sapiens_hsa05012 | 0.90951514 |
75 | Apoptosis_Homo sapiens_hsa04210 | 0.86561044 |
76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.86355257 |
77 | Sulfur relay system_Homo sapiens_hsa04122 | 0.86297892 |
78 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.86272074 |
79 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.86020504 |
80 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.85285517 |
81 | Shigellosis_Homo sapiens_hsa05131 | 0.80804142 |
82 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.79768995 |
83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.79191789 |
84 | Asthma_Homo sapiens_hsa05310 | 0.78028987 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.77565286 |
86 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.76862320 |
87 | Base excision repair_Homo sapiens_hsa03410 | 0.76388680 |
88 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.76121793 |
89 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76117110 |
90 | Endocytosis_Homo sapiens_hsa04144 | 0.75632791 |
91 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.75294824 |
92 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.75257916 |
93 | DNA replication_Homo sapiens_hsa03030 | 0.74007461 |
94 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.71754224 |
95 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.71497115 |
96 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.71359139 |
97 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70316883 |
98 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.68273524 |
99 | Influenza A_Homo sapiens_hsa05164 | 0.67323003 |
100 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.66462752 |
101 | Mismatch repair_Homo sapiens_hsa03430 | 0.66364741 |
102 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.65871719 |
103 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.65401975 |
104 | Purine metabolism_Homo sapiens_hsa00230 | 0.64929404 |
105 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.61433678 |
106 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60776914 |
107 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.60388287 |
108 | Protein export_Homo sapiens_hsa03060 | 0.59334048 |
109 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.59137888 |
110 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.58541772 |
111 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.56667515 |
112 | Spliceosome_Homo sapiens_hsa03040 | 0.56337420 |
113 | Salmonella infection_Homo sapiens_hsa05132 | 0.56194409 |
114 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.55609896 |
115 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54370700 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.53549462 |
117 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.52423763 |
118 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.51379859 |
119 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.50861024 |
120 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.49884103 |
121 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.48495806 |
122 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43078412 |
123 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.38548868 |
124 | Homologous recombination_Homo sapiens_hsa03440 | 0.37043301 |
125 | Malaria_Homo sapiens_hsa05144 | 0.34487825 |