RTN4RL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.33693643
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.02707186
3synaptic vesicle maturation (GO:0016188)4.78902644
4synaptic vesicle exocytosis (GO:0016079)4.62064260
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.58775192
6glutamate secretion (GO:0014047)4.54464467
7adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.53502309
8vocalization behavior (GO:0071625)4.50540368
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.36445331
10protein localization to synapse (GO:0035418)4.35430687
11regulation of synaptic vesicle exocytosis (GO:2000300)4.33491881
12locomotory exploration behavior (GO:0035641)4.23931041
13synaptic vesicle docking involved in exocytosis (GO:0016081)4.14881995
14neuronal action potential propagation (GO:0019227)4.12160881
15regulation of glutamate receptor signaling pathway (GO:1900449)4.06086972
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.04987808
17cellular potassium ion homeostasis (GO:0030007)4.03698142
18regulation of synaptic vesicle transport (GO:1902803)3.93922772
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.84346879
20glutamate receptor signaling pathway (GO:0007215)3.80897557
21cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.79337639
22regulation of neuronal synaptic plasticity (GO:0048168)3.77864162
23response to parathyroid hormone (GO:0071107)3.76392387
24neuronal ion channel clustering (GO:0045161)3.76095104
25sodium ion export (GO:0071436)3.68001444
26synaptic transmission, glutamatergic (GO:0035249)3.64630730
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.63597718
28neuron cell-cell adhesion (GO:0007158)3.61153349
29exploration behavior (GO:0035640)3.60070986
30dopamine receptor signaling pathway (GO:0007212)3.55381923
31neurotransmitter secretion (GO:0007269)3.52097192
32cell migration in hindbrain (GO:0021535)3.48603894
33proline transport (GO:0015824)3.46823891
34regulation of synapse structural plasticity (GO:0051823)3.45663603
35neurotransmitter-gated ion channel clustering (GO:0072578)3.45383305
36neuron-neuron synaptic transmission (GO:0007270)3.45126559
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.43707418
38membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43662465
39innervation (GO:0060384)3.42268851
40cell communication by electrical coupling (GO:0010644)3.39375685
41cerebellar granule cell differentiation (GO:0021707)3.32572216
42positive regulation of synapse maturation (GO:0090129)3.31733245
43cerebellar Purkinje cell differentiation (GO:0021702)3.31692811
44regulation of postsynaptic membrane potential (GO:0060078)3.29437913
45negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.28203812
46positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.27638536
47detection of calcium ion (GO:0005513)3.25165546
48gamma-aminobutyric acid signaling pathway (GO:0007214)3.24931702
49G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.24366414
50long-term memory (GO:0007616)3.23798925
51regulation of synaptic plasticity (GO:0048167)3.23514907
52activation of protein kinase A activity (GO:0034199)3.21374375
53cytoskeletal anchoring at plasma membrane (GO:0007016)3.18819846
54layer formation in cerebral cortex (GO:0021819)3.17515806
55membrane depolarization during action potential (GO:0086010)3.17392559
56synaptic vesicle endocytosis (GO:0048488)3.13139479
57positive regulation of membrane potential (GO:0045838)3.12710433
58dendritic spine organization (GO:0097061)3.11717772
59regulation of glycogen (starch) synthase activity (GO:2000465)3.09509844
60long-term synaptic potentiation (GO:0060291)3.05728839
61regulation of neurotransmitter secretion (GO:0046928)3.04635255
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.03630960
63G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.01875528
64chemosensory behavior (GO:0007635)3.01027092
65neuromuscular process controlling posture (GO:0050884)3.00672351
66apical protein localization (GO:0045176)3.00466685
67gamma-aminobutyric acid transport (GO:0015812)2.99815354
68cell-cell junction maintenance (GO:0045217)2.99409594
69membrane depolarization (GO:0051899)2.97075227
70neurotransmitter transport (GO:0006836)2.95211858
71neuron recognition (GO:0008038)2.94681622
72membrane repolarization (GO:0086009)2.94328445
73potassium ion import (GO:0010107)2.94287992
74dendritic spine morphogenesis (GO:0060997)2.93291569
75regulation of vesicle fusion (GO:0031338)2.91515889
76positive regulation of neurotransmitter secretion (GO:0001956)2.90509635
77ear development (GO:0043583)2.90160357
78regulation of synapse maturation (GO:0090128)2.88304322
79behavioral fear response (GO:0001662)2.88150246
80behavioral defense response (GO:0002209)2.88150246
81positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.87876452
82fear response (GO:0042596)2.86931946
83neuromuscular process controlling balance (GO:0050885)2.85811178
84mating behavior (GO:0007617)2.83752685
85regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.83506147
86negative regulation of synaptic transmission, GABAergic (GO:0032229)2.83222363
87regulation of dendritic spine morphogenesis (GO:0061001)2.82888857
88regulation of synaptic transmission, glutamatergic (GO:0051966)2.82002244
89cellular sodium ion homeostasis (GO:0006883)2.80642033
90regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.80348921
91cell communication involved in cardiac conduction (GO:0086065)2.79902335
92positive regulation of neurotransmitter transport (GO:0051590)2.77273478
93axon extension (GO:0048675)2.74884201
94long term synaptic depression (GO:0060292)2.74872369
95regulation of ARF protein signal transduction (GO:0032012)2.74589356
96semaphorin-plexin signaling pathway (GO:0071526)2.74559530
97collecting duct development (GO:0072044)2.74481665
98potassium ion homeostasis (GO:0055075)2.73399924
99positive regulation of potassium ion transmembrane transport (GO:1901381)2.72282210
100regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.72165024
101regulation of neurotransmitter transport (GO:0051588)2.70643960
102synaptic transmission (GO:0007268)2.68979056
103regulation of neurotransmitter levels (GO:0001505)2.68741136
104transmission of nerve impulse (GO:0019226)2.68450228
105membrane hyperpolarization (GO:0060081)2.68101427
106response to histamine (GO:0034776)2.67277414
107axonal fasciculation (GO:0007413)2.67163174
108membrane repolarization during action potential (GO:0086011)2.65895094
109positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.63638859
110regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.62978271
111regulation of amyloid precursor protein catabolic process (GO:1902991)2.61910359
112positive regulation of dendritic spine development (GO:0060999)2.61720453
113regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.61661591
114response to auditory stimulus (GO:0010996)2.61171851
115vesicle transport along microtubule (GO:0047496)2.61052658
116regulation of synaptic transmission (GO:0050804)2.61030034
117membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.60766636
118negative regulation of catenin import into nucleus (GO:0035414)2.60570202
119dendrite morphogenesis (GO:0048813)2.59437523
120postsynaptic membrane organization (GO:0001941)2.58809372
121regulation of voltage-gated calcium channel activity (GO:1901385)2.58068298
122regulation of axon extension involved in axon guidance (GO:0048841)2.57138729
123positive regulation of dendrite development (GO:1900006)2.56069786
124neuron projection extension (GO:1990138)2.55989082
125desmosome organization (GO:0002934)2.55723803
126behavioral response to cocaine (GO:0048148)2.55405174
127establishment of mitochondrion localization (GO:0051654)2.54093901
128cellular response to monoamine stimulus (GO:0071868)2.53276643
129cellular response to catecholamine stimulus (GO:0071870)2.53276643
130phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.51659766
131establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.49477804
132mitochondrion transport along microtubule (GO:0047497)2.49477804
133protein retention in ER lumen (GO:0006621)2.46714663
134cell junction maintenance (GO:0034331)2.46138319
135cellular response to glucagon stimulus (GO:0071377)2.43763586
136cerebellar Purkinje cell layer development (GO:0021680)2.41337169
137asymmetric protein localization (GO:0008105)2.38539074
138positive regulation of dendritic spine morphogenesis (GO:0061003)2.36781526
139uterus development (GO:0060065)2.36545699
140acid secretion (GO:0046717)2.35612376
141peptidyl-tyrosine autophosphorylation (GO:0038083)2.35338647
142amino acid import (GO:0043090)2.33270784

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.22272509
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.74686027
3GBX2_23144817_ChIP-Seq_PC3_Human3.46536973
4ESR2_21235772_ChIP-Seq_MCF-7_Human3.16921958
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04914259
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02073180
7TP63_17297297_ChIP-ChIP_HaCaT_Human2.92891146
8* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.83086459
9* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64836351
10* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64836351
11* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.57938258
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57289094
13REST_21632747_ChIP-Seq_MESCs_Mouse2.55461484
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51047754
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.50787843
16DROSHA_22980978_ChIP-Seq_HELA_Human2.42477264
17* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41449781
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38749210
19ESR1_21235772_ChIP-Seq_MCF-7_Human2.38080653
20* RARB_27405468_Chip-Seq_BRAIN_Mouse2.37102599
21ESR1_20079471_ChIP-ChIP_T-47D_Human2.21540160
22* EZH2_27304074_Chip-Seq_ESCs_Mouse2.18848475
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.13636949
24* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.11421446
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.10283800
26LXR_22292898_ChIP-Seq_THP-1_Human2.10226654
27* EED_16625203_ChIP-ChIP_MESCs_Mouse2.08909179
28* RACK7_27058665_Chip-Seq_MCF-7_Human2.01127652
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.98263782
30* RNF2_27304074_Chip-Seq_ESCs_Mouse1.96882873
31ESR1_15608294_ChIP-ChIP_MCF-7_Human1.83506693
32* TP53_20018659_ChIP-ChIP_R1E_Mouse1.75263795
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.71477252
34ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.70529629
35KDM2B_26808549_Chip-Seq_SUP-B15_Human1.68872073
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66786146
37SMAD4_21799915_ChIP-Seq_A2780_Human1.64486064
38EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60909427
39PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.59774744
40NR3C1_23031785_ChIP-Seq_PC12_Mouse1.58436312
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.58421821
42ZNF263_19887448_ChIP-Seq_K562_Human1.58255804
43SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.53771036
44CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52117729
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50244864
46TAF15_26573619_Chip-Seq_HEK293_Human1.49266323
47* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.49057399
48SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.48852144
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.48442705
50CREB1_26743006_Chip-Seq_LNCaP_Human1.47555488
51SMC4_20622854_ChIP-Seq_HELA_Human1.47405415
52* RUNX1_27514584_Chip-Seq_MCF-7_Human1.45975446
53P68_20966046_ChIP-Seq_HELA_Human1.43958953
54ERG_21242973_ChIP-ChIP_JURKAT_Human1.42695569
55TET1_21451524_ChIP-Seq_MESCs_Mouse1.42448572
56ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.41369583
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.41115815
58KDM2B_26808549_Chip-Seq_DND41_Human1.35444089
59RARG_19884340_ChIP-ChIP_MEFs_Mouse1.34486234
60UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.34174793
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.34069854
62AR_21572438_ChIP-Seq_LNCaP_Human1.33727782
63GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.33542497
64CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.30612171
65SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30331763
66TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29580871
67P300_19829295_ChIP-Seq_ESCs_Human1.29332773
68OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.28383831
69ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26861068
70SOX2_21211035_ChIP-Seq_LN229_Gbm1.25746507
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.25162713
72SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.24232844
73* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24184167
74* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.24079587
75ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.21007074
76AR_25329375_ChIP-Seq_VCAP_Human1.20605951
77* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20211937
78* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.19443784
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18511157
80AR_19668381_ChIP-Seq_PC3_Human1.18084203
81* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.17122851
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.16804712
83* STAT3_23295773_ChIP-Seq_U87_Human1.16804152
84RING1B_27294783_Chip-Seq_ESCs_Mouse1.16399880
85ARNT_22903824_ChIP-Seq_MCF-7_Human1.16338887
86ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15920125
87* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15675218
88TRIM28_21343339_ChIP-Seq_HEK293_Human1.14955323
89ZNF274_21170338_ChIP-Seq_K562_Hela1.14428062
90KDM2B_26808549_Chip-Seq_K562_Human1.13797586
91AHR_22903824_ChIP-Seq_MCF-7_Human1.13705191
92SRY_22984422_ChIP-ChIP_TESTIS_Rat1.12733568
93BCAT_22108803_ChIP-Seq_LS180_Human1.12127384
94* SMAD3_21741376_ChIP-Seq_EPCs_Human1.11242391
95MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.09499702
96CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08538415
97TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.08513218
98PIAS1_25552417_ChIP-Seq_VCAP_Human1.08475720
99DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08102662
100* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04695575
101THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04633501
102VDR_22108803_ChIP-Seq_LS180_Human1.04453641
103* CBX2_27304074_Chip-Seq_ESCs_Mouse1.03854609
104SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.03666714
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.03658595
106PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03259840
107* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02018800
108SA1_27219007_Chip-Seq_ERYTHROID_Human1.01949663
109EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.01542080
110ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.01038761
111STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00048313
112AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99663425
113TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99535737
114* SMAD4_21741376_ChIP-Seq_HESCs_Human0.99303517
115KDM2B_26808549_Chip-Seq_JURKAT_Human0.98911482
116OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98869428
117TCF4_23295773_ChIP-Seq_U87_Human0.98607685
118WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98459159
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98234346
120GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97791193
121P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97631624
122* SMAD3_21741376_ChIP-Seq_HESCs_Human0.97480721
123BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97110104
124VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96938397
125* CTCF_27219007_Chip-Seq_Bcells_Human0.96448224
126* OCT4_19829295_ChIP-Seq_ESCs_Human0.96427238
127ELK3_25401928_ChIP-Seq_HUVEC_Human0.95397230
128* RING1B_27294783_Chip-Seq_NPCs_Mouse0.94776182
129MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94344686
130TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93632339
131GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93535138
132TCF7_22412390_ChIP-Seq_EML_Mouse0.93403594
133NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.91562069
134ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91291121
135CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91289026
136HIF1A_21447827_ChIP-Seq_MCF-7_Human0.90228694
137YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90176361
138RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.89423763
139EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.89228005
140SMAD3_21741376_ChIP-Seq_ESCs_Human0.89156565
141RUNX2_22187159_ChIP-Seq_PCA_Human0.89046524
142UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88649721
143* SOX3_22085726_ChIP-Seq_NPCs_Mouse0.88510796
144TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87890713
145POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87890713
146TP63_22573176_ChIP-Seq_HFKS_Human0.87482730
147* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87305330
148EP300_21415370_ChIP-Seq_HL-1_Mouse0.87223638
149NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85704619
150TET1_21490601_ChIP-Seq_MESCs_Mouse0.85527904
151ZFP281_18757296_ChIP-ChIP_E14_Mouse0.83756250
152SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83364041
153TP53_16413492_ChIP-PET_HCT116_Human0.82944132

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.07058850
2MP0003880_abnormal_central_pattern4.47473690
3MP0003635_abnormal_synaptic_transmissio3.88231789
4MP0003123_paternal_imprinting3.87140056
5MP0004270_analgesia3.82444741
6MP0001968_abnormal_touch/_nociception3.33684991
7MP0009745_abnormal_behavioral_response3.17991646
8MP0002063_abnormal_learning/memory/cond3.08910663
9MP0002064_seizures2.96168785
10MP0002735_abnormal_chemical_nociception2.87167607
11MP0002736_abnormal_nociception_after2.75643701
12MP0002572_abnormal_emotion/affect_behav2.58174050
13MP0002734_abnormal_mechanical_nocicepti2.55148101
14MP0002272_abnormal_nervous_system2.53941751
15MP0002822_catalepsy2.44797495
16MP0009046_muscle_twitch2.38268744
17MP0009780_abnormal_chondrocyte_physiolo2.28612836
18MP0001501_abnormal_sleep_pattern2.27239763
19MP0004858_abnormal_nervous_system2.22563277
20MP0002909_abnormal_adrenal_gland2.22126132
21MP0002733_abnormal_thermal_nociception2.15881266
22MP0003329_amyloid_beta_deposits2.09336464
23MP0001970_abnormal_pain_threshold2.09039818
24MP0003705_abnormal_hypodermis_morpholog2.07864490
25MP0001486_abnormal_startle_reflex2.06370010
26MP0001440_abnormal_grooming_behavior2.05774368
27MP0005409_darkened_coat_color1.95049900
28MP0002067_abnormal_sensory_capabilities1.94330996
29MP0005423_abnormal_somatic_nervous1.88656966
30MP0000579_abnormal_nail_morphology1.88371661
31MP0006276_abnormal_autonomic_nervous1.85776369
32MP0010030_abnormal_orbit_morphology1.83823073
33MP0010234_abnormal_vibrissa_follicle1.79190737
34MP0001346_abnormal_lacrimal_gland1.78231756
35MP0002837_dystrophic_cardiac_calcinosis1.77499797
36MP0000462_abnormal_digestive_system1.71154499
37MP0003879_abnormal_hair_cell1.70958473
38MP0002796_impaired_skin_barrier1.70552955
39MP0001984_abnormal_olfaction1.68837077
40MP0002184_abnormal_innervation1.66885576
41MP0008569_lethality_at_weaning1.63688922
42MP0002557_abnormal_social/conspecific_i1.55613985
43MP0004811_abnormal_neuron_physiology1.52293274
44MP0003633_abnormal_nervous_system1.47672902
45MP0000566_synostosis1.46384464
46MP0004924_abnormal_behavior1.44879819
47MP0005386_behavior/neurological_phenoty1.44879819
48MP0002249_abnormal_larynx_morphology1.44857079
49MP0010386_abnormal_urinary_bladder1.42016778
50MP0001502_abnormal_circadian_rhythm1.40970438
51MP0005551_abnormal_eye_electrophysiolog1.39984466
52MP0000013_abnormal_adipose_tissue1.38350431
53MP0003122_maternal_imprinting1.37349736
54MP0000778_abnormal_nervous_system1.33803763
55MP0000955_abnormal_spinal_cord1.33559578
56MP0001348_abnormal_lacrimal_gland1.30282468
57MP0005248_abnormal_Harderian_gland1.29667621
58MP0002882_abnormal_neuron_morphology1.28471772
59MP0005535_abnormal_body_temperature1.25452091
60MP0002066_abnormal_motor_capabilities/c1.24711032
61MP0002653_abnormal_ependyma_morphology1.18898048
62MP0002229_neurodegeneration1.16154056
63MP0000534_abnormal_ureter_morphology1.14975933
64MP0009379_abnormal_foot_pigmentation1.14782608
65MP0004381_abnormal_hair_follicle1.14679786
66MP0000604_amyloidosis1.14463295
67MP0004145_abnormal_muscle_electrophysio1.13529547
68MP0003942_abnormal_urinary_system1.12643675
69MP0002090_abnormal_vision1.12431571
70MP0004085_abnormal_heartbeat1.11683090
71MP0003631_nervous_system_phenotype1.10747750
72MP0008874_decreased_physiological_sensi1.09695712
73MP0002098_abnormal_vibrissa_morphology1.06110851
74MP0003075_altered_response_to1.04882149
75MP0008961_abnormal_basal_metabolism1.02728024
76MP0003183_abnormal_peptide_metabolism1.01939639
77MP0000751_myopathy1.01217843
78MP0002876_abnormal_thyroid_physiology0.98529551
79MP0004510_myositis0.97732807
80MP0004215_abnormal_myocardial_fiber0.96276149
81MP0002069_abnormal_eating/drinking_beha0.96053518
82MP0008872_abnormal_physiological_respon0.95093267
83MP0005646_abnormal_pituitary_gland0.93637536
84MP0004484_altered_response_of0.92998420
85MP0002638_abnormal_pupillary_reflex0.92324861
86MP0001905_abnormal_dopamine_level0.92102351
87MP0005645_abnormal_hypothalamus_physiol0.89703185
88MP0004885_abnormal_endolymph0.88803604
89MP0001765_abnormal_ion_homeostasis0.88197498
90MP0003787_abnormal_imprinting0.87979225
91MP0003121_genomic_imprinting0.87875090
92MP0004133_heterotaxia0.87604880
93MP0004043_abnormal_pH_regulation0.87229776
94MP0003172_abnormal_lysosome_physiology0.86688296
95MP0003045_fibrosis0.85845109
96MP0002089_abnormal_postnatal_growth/wei0.85184518
97MP0001849_ear_inflammation0.84249468
98MP0001664_abnormal_digestion0.84178366
99MP0004264_abnormal_extraembryonic_tissu0.83309072
100MP0005501_abnormal_skin_physiology0.83121924
101MP0004142_abnormal_muscle_tone0.82940375
102MP0002152_abnormal_brain_morphology0.82486331
103MP0004130_abnormal_muscle_cell0.81921234
104MP0003861_abnormal_nervous_system0.80440383
105MP0003938_abnormal_ear_development0.77395882
106MP0003634_abnormal_glial_cell0.76260591
107MP0001177_atelectasis0.76222870
108MP0001529_abnormal_vocalization0.75890873
109MP0000427_abnormal_hair_cycle0.74665591
110MP0006072_abnormal_retinal_apoptosis0.73090031
111MP0005670_abnormal_white_adipose0.71867189
112MP0001986_abnormal_taste_sensitivity0.71278333
113MP0000383_abnormal_hair_follicle0.71169701
114MP0000230_abnormal_systemic_arterial0.70715247
115MP0001963_abnormal_hearing_physiology0.70711817
116MP0004782_abnormal_surfactant_physiolog0.70609673
117MP0010678_abnormal_skin_adnexa0.70388464
118MP0000538_abnormal_urinary_bladder0.69769317
119MP0003878_abnormal_ear_physiology0.69636892
120MP0005377_hearing/vestibular/ear_phenot0.69636892
121MP0002160_abnormal_reproductive_system0.69558481
122MP0003690_abnormal_glial_cell0.69413709
123MP0009384_cardiac_valve_regurgitation0.69022629
124MP0003137_abnormal_impulse_conducting0.68765473
125MP0004036_abnormal_muscle_relaxation0.68142735
126MP0002752_abnormal_somatic_nervous0.67707857
127MP0005076_abnormal_cell_differentiation0.67250773
128MP0010771_integument_phenotype0.66033153
129MP0001188_hyperpigmentation0.66008637
130MP0003283_abnormal_digestive_organ0.65684187
131MP0009672_abnormal_birth_weight0.64097558
132MP0000003_abnormal_adipose_tissue0.63957350
133MP0000026_abnormal_inner_ear0.63684493
134MP0004233_abnormal_muscle_weight0.62952406
135MP0003011_delayed_dark_adaptation0.62032747
136MP0002078_abnormal_glucose_homeostasis0.61520347
137MP0005595_abnormal_vascular_smooth0.60562675
138MP0002116_abnormal_craniofacial_bone0.60550381
139MP0000747_muscle_weakness0.59831160
140MP0005620_abnormal_muscle_contractility0.58845108
141MP0008004_abnormal_stomach_pH0.58093678
142MP0003953_abnormal_hormone_level0.57751578
143MP0004742_abnormal_vestibular_system0.57181916
144MP0005187_abnormal_penis_morphology0.56469342
145MP0005253_abnormal_eye_physiology0.55056056
146MP0003632_abnormal_nervous_system0.54745818
147MP0000920_abnormal_myelination0.54559659

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.16731893
2Myokymia (HP:0002411)6.12879943
3Focal seizures (HP:0007359)5.36442246
4Visual hallucinations (HP:0002367)5.26243386
5Atonic seizures (HP:0010819)4.63044191
6Epileptic encephalopathy (HP:0200134)4.40813059
7Absence seizures (HP:0002121)4.40256202
8Febrile seizures (HP:0002373)4.35838642
9Action tremor (HP:0002345)4.33576124
10Dialeptic seizures (HP:0011146)3.97484517
11Progressive cerebellar ataxia (HP:0002073)3.97365569
12Generalized tonic-clonic seizures (HP:0002069)3.87610742
13Obstructive sleep apnea (HP:0002870)3.67192366
14Supranuclear gaze palsy (HP:0000605)3.33504891
15Ventricular fibrillation (HP:0001663)3.19134263
16Depression (HP:0000716)3.12916854
17Truncal ataxia (HP:0002078)3.11499210
18J-shaped sella turcica (HP:0002680)3.09564973
19Amblyopia (HP:0000646)3.06236031
20Hyperventilation (HP:0002883)3.04527262
21Hyperacusis (HP:0010780)3.02781107
22Mutism (HP:0002300)3.00598085
23Anxiety (HP:0000739)2.97665846
24Abnormality of the lower motor neuron (HP:0002366)2.88076476
25Dysmetria (HP:0001310)2.88003521
26Pheochromocytoma (HP:0002666)2.85639657
27Dysdiadochokinesis (HP:0002075)2.84545840
28Gaze-evoked nystagmus (HP:0000640)2.83329878
29Cerebral inclusion bodies (HP:0100314)2.78986911
30Hyperthyroidism (HP:0000836)2.76792185
31Poor eye contact (HP:0000817)2.75415497
32Enlarged penis (HP:0000040)2.74717097
33Septate vagina (HP:0001153)2.73438267
34Hyperparathyroidism (HP:0000843)2.68545142
35Impaired vibration sensation in the lower limbs (HP:0002166)2.66972850
36Postural instability (HP:0002172)2.66728863
37Macroorchidism (HP:0000053)2.65836003
38Germ cell neoplasia (HP:0100728)2.64245902
39Abnormal social behavior (HP:0012433)2.61786976
40Impaired social interactions (HP:0000735)2.61786976
41Urinary bladder sphincter dysfunction (HP:0002839)2.61728549
42Syncope (HP:0001279)2.59459505
43Asymmetry of the thorax (HP:0001555)2.58463371
44Epileptiform EEG discharges (HP:0011182)2.58108058
45Broad-based gait (HP:0002136)2.56944075
46Neurofibrillary tangles (HP:0002185)2.55624041
47Insomnia (HP:0100785)2.51046393
48Abnormal eating behavior (HP:0100738)2.50624725
49Excessive salivation (HP:0003781)2.50261554
50Drooling (HP:0002307)2.50261554
51Impaired smooth pursuit (HP:0007772)2.49608880
52Spinal cord compression (HP:0002176)2.49008155
53Akinesia (HP:0002304)2.45926663
54Distal lower limb muscle weakness (HP:0009053)2.44871572
55Concave nail (HP:0001598)2.44187663
56Scanning speech (HP:0002168)2.43887680
57Neuroendocrine neoplasm (HP:0100634)2.43785119
58Lymphangioma (HP:0100764)2.42673604
59Genetic anticipation (HP:0003743)2.40702752
60Hemiplegia (HP:0002301)2.39173595
61EEG with generalized epileptiform discharges (HP:0011198)2.39163146
62Hemiparesis (HP:0001269)2.36562540
63Status epilepticus (HP:0002133)2.34532101
64Termporal pattern (HP:0011008)2.31747668
65Insidious onset (HP:0003587)2.31747668
66Dysmetric saccades (HP:0000641)2.30964026
67Ankle clonus (HP:0011448)2.29378386
68Agitation (HP:0000713)2.27731625
69Abnormality of the aortic arch (HP:0012303)2.27150298
70Rapidly progressive (HP:0003678)2.26237928
71Torticollis (HP:0000473)2.25701770
72Prolonged QT interval (HP:0001657)2.24578378
73Bradykinesia (HP:0002067)2.24442488
74Diplopia (HP:0000651)2.22317631
75Abnormality of binocular vision (HP:0011514)2.22317631
76Retinal atrophy (HP:0001105)2.19411121
77Thin bony cortex (HP:0002753)2.18855050
78Neuronal loss in central nervous system (HP:0002529)2.18461950
79Focal dystonia (HP:0004373)2.17021322
80Decreased circulating renin level (HP:0003351)2.16780287
81Growth hormone excess (HP:0000845)2.16534745
82Hypsarrhythmia (HP:0002521)2.16235524
83Buphthalmos (HP:0000557)2.16053481
84Double outlet right ventricle (HP:0001719)2.15507698
85Congenital malformation of the right heart (HP:0011723)2.15507698
86Abnormal EKG (HP:0003115)2.13514170
87Asymmetric growth (HP:0100555)2.09861323
88Intention tremor (HP:0002080)2.09751000
89Abnormality of ocular smooth pursuit (HP:0000617)2.09040686
90Spinal canal stenosis (HP:0003416)2.08141875
91Sleep apnea (HP:0010535)2.06896134
92Testicular neoplasm (HP:0010788)2.06134141
93Urinary urgency (HP:0000012)2.05470445
94Psychosis (HP:0000709)2.04893665
95Stereotypic behavior (HP:0000733)2.04422544
96Lower limb asymmetry (HP:0100559)2.03111759
97Sudden death (HP:0001699)2.02185976
98Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.01269344
99Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.00903598
100Abnormal pancreas size (HP:0012094)2.00614848
101Central scotoma (HP:0000603)2.00363823
102Craniofacial dystonia (HP:0012179)1.99284246
103Pointed chin (HP:0000307)1.97851708
104Global brain atrophy (HP:0002283)1.97754127
105Hypokinesia (HP:0002375)1.97675646
106Upper limb amyotrophy (HP:0009129)1.97340348
107Distal upper limb amyotrophy (HP:0007149)1.97340348
108Spastic gait (HP:0002064)1.96811724
109Inability to walk (HP:0002540)1.96106504
110Orthostatic hypotension (HP:0001278)1.94644570
111Impaired vibratory sensation (HP:0002495)1.92764410
112Papilledema (HP:0001085)1.92039946
113Precocious puberty (HP:0000826)1.91635017
114Generalized myoclonic seizures (HP:0002123)1.91185125
115Limb dystonia (HP:0002451)1.90276041
116Deformed sella turcica (HP:0002681)1.89397247
117Elfin facies (HP:0004428)1.89197552
118Abnormality of the corticospinal tract (HP:0002492)1.87753436
119Postural tremor (HP:0002174)1.87502446
120Hand muscle atrophy (HP:0009130)1.87086597
121Overriding aorta (HP:0002623)1.85918149
122Gait ataxia (HP:0002066)1.85466204
123Heterochromia iridis (HP:0001100)1.83730418
124Testicular atrophy (HP:0000029)1.82646206
125Hypoventilation (HP:0002791)1.82564327
126Delusions (HP:0000746)1.81757106
127Hyporeflexia of lower limbs (HP:0002600)1.81199019
128Congenital glaucoma (HP:0001087)1.80905050
129Impaired pain sensation (HP:0007328)1.80712698
130Abnormality of pain sensation (HP:0010832)1.80712698
131Hypercalcemia (HP:0003072)1.80673913
132Diminished movement (HP:0002374)1.80457254
133Absent speech (HP:0001344)1.79885631
134Dysautonomia (HP:0002459)1.79034143
135Bundle branch block (HP:0011710)1.79012953
136Hypercortisolism (HP:0001578)1.78935847
137Back pain (HP:0003418)1.76354086
138Neonatal hypoglycemia (HP:0001998)1.76342907
139Annular pancreas (HP:0001734)1.76111823
140Turricephaly (HP:0000262)1.75963985
141Exotropia (HP:0000577)1.75733494
142Neoplasm of the adrenal cortex (HP:0100641)1.74567319
143Shallow orbits (HP:0000586)1.74454143
144Aplasia involving bones of the extremities (HP:0009825)1.74079593
145Aplasia involving bones of the upper limbs (HP:0009823)1.74079593
146Aplasia of the phalanges of the hand (HP:0009802)1.74079593
147Cholecystitis (HP:0001082)1.73369636
148Abnormal gallbladder physiology (HP:0012438)1.73369636
149Abnormality of macular pigmentation (HP:0008002)1.72913403
150Lower limb muscle weakness (HP:0007340)1.72196230
151Abnormality of salivation (HP:0100755)1.70608807
152Apathy (HP:0000741)1.67513353
153Long palpebral fissure (HP:0000637)1.65544081
154Hepatoblastoma (HP:0002884)1.65466093
155Ulnar claw (HP:0001178)1.64777625
156Bronchomalacia (HP:0002780)1.64664468
157Amelogenesis imperfecta (HP:0000705)1.62383554
158Acanthosis nigricans (HP:0000956)1.62151299
159Long toe (HP:0010511)1.59332122
160Aplasia/Hypoplasia of the sacrum (HP:0008517)1.59038340

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.59669827
2NTRK34.45613603
3EPHA44.03939104
4MAP3K93.61357088
5SIK13.18510362
6DAPK22.82078635
7RIPK42.69705095
8MINK12.62300389
9MAP3K42.54425697
10PKN22.43881386
11KSR22.41960675
12NTRK12.14967217
13GRK52.09144873
14EPHA22.09092072
15PRKD32.02207779
16MAP2K71.98396356
17MAP2K41.83348170
18MARK11.83031730
19CAMKK11.82255657
20MAPKAPK31.79532701
21EEF2K1.79516837
22MAP3K21.75915516
23SMG11.75206970
24PAK61.73503731
25ICK1.67481705
26DAPK11.61337150
27MAP3K121.58375956
28TESK11.57567127
29CASK1.56923347
30ARAF1.53181372
31CAMKK21.51593773
32RPS6KB21.51308403
33PLK21.49971778
34PTK2B1.47869747
35CDK51.43756550
36MAP2K21.43348179
37KSR11.41881602
38SIK21.36245568
39MUSK1.35143237
40NTRK21.34844279
41NEK61.34032010
42SCYL21.33530226
43STK381.33149326
44MAP3K131.25628160
45PRKCG1.20635732
46PNCK1.18357550
47FES1.16136482
48INSRR1.15855411
49LMTK21.14227136
50CAMK11.10826091
51RET1.05476067
52CAMK2A1.05415584
53MAPK131.05384932
54CAMK1D1.04074322
55BRAF1.03339295
56BMPR21.00206672
57PIK3CA0.97775965
58GRK70.96231077
59PRPF4B0.93846393
60FER0.92718092
61AKT30.91452056
62PRKCH0.91129159
63CAMK2B0.88204566
64CAMK1G0.87434532
65SIK30.87362544
66PHKG20.85992032
67PHKG10.85992032
68SGK2230.85983380
69SGK4940.85983380
70SGK20.84517924
71MAP3K70.83951764
72STK110.82677046
73MTOR0.82653116
74PRKCI0.81753630
75PTK20.81437903
76PDK10.79034343
77MAP3K10.77397788
78MAPK120.76990483
79MAPK150.75395298
80PAK30.73525250
81PDPK10.71769641
82UHMK10.71247897
83WNK40.70193863
84MARK20.70089649
85SGK30.70018344
86FGFR20.69556682
87RAF10.68961905
88PINK10.66681636
89BRSK10.66532646
90TNIK0.66236653
91CAMK40.65849818
92LIMK10.64446422
93CDK140.64296133
94CDK180.62927018
95TAOK10.62691824
96MAP3K60.62013488
97FGFR40.61991082
98SGK10.61631078
99TNK20.61236273
100MAP2K10.60884376
101DYRK1A0.60463517
102CAMK2D0.60387076
103CDC42BPA0.60182660
104DAPK30.60137172
105IRAK20.59780577
106CDK150.58290496
107PRKCZ0.57605549
108LATS20.57167602
109PRKCE0.56199773
110WNK10.55847925
111ILK0.55123426
112PTK60.54454866
113NME10.53888685
114LRRK20.50987181
115HIPK20.50139278
116CDK190.48993370
117CDK11A0.48952350
118MAP3K110.48946316
119RIPK10.48906620
120TYRO30.46648208
121CAMK2G0.46414308
122RPS6KL10.45267418
123RPS6KC10.45267418
124RPS6KA20.45252209
125PDGFRA0.43908931
126RPS6KB10.43882722
127FRK0.43418836
128PRKD10.43023849
129MAPK80.42966711
130TAF10.42058024
131RPS6KA30.42018145
132FYN0.39700896
133MAPK40.39668209
134OXSR10.38372268
135DMPK0.37157953
136PRKD20.37105644
137PRKACA0.36205988
138MAPK100.36011149
139PRKCA0.33483449
140MYLK0.33458633

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.28406823
2Synaptic vesicle cycle_Homo sapiens_hsa047212.87245295
3Long-term potentiation_Homo sapiens_hsa047202.62230793
4Olfactory transduction_Homo sapiens_hsa047402.57239235
5Circadian entrainment_Homo sapiens_hsa047132.53167582
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.49444633
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.33763427
8Amphetamine addiction_Homo sapiens_hsa050312.31505538
9Glutamatergic synapse_Homo sapiens_hsa047242.30568145
10GABAergic synapse_Homo sapiens_hsa047272.28782035
11Morphine addiction_Homo sapiens_hsa050322.21364551
12Salivary secretion_Homo sapiens_hsa049702.19052611
13Insulin secretion_Homo sapiens_hsa049112.15599217
14Aldosterone synthesis and secretion_Homo sapiens_hsa049252.01688331
15Dopaminergic synapse_Homo sapiens_hsa047281.96469504
16Taste transduction_Homo sapiens_hsa047421.88491854
17Gastric acid secretion_Homo sapiens_hsa049711.75065773
18Renin secretion_Homo sapiens_hsa049241.73817606
19Cholinergic synapse_Homo sapiens_hsa047251.73130202
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.62457504
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.56385690
22Calcium signaling pathway_Homo sapiens_hsa040201.56099361
23Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.55667677
24Oxytocin signaling pathway_Homo sapiens_hsa049211.54073681
25Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.51600453
26Serotonergic synapse_Homo sapiens_hsa047261.47338125
27Long-term depression_Homo sapiens_hsa047301.42097530
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.41800573
29Collecting duct acid secretion_Homo sapiens_hsa049661.41611844
30Cocaine addiction_Homo sapiens_hsa050301.33202563
31GnRH signaling pathway_Homo sapiens_hsa049121.30883046
32Phototransduction_Homo sapiens_hsa047441.29482090
33cAMP signaling pathway_Homo sapiens_hsa040241.28563376
34Type II diabetes mellitus_Homo sapiens_hsa049301.24474252
35cGMP-PKG signaling pathway_Homo sapiens_hsa040221.20398274
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.19669363
37AMPK signaling pathway_Homo sapiens_hsa041521.16663833
38Estrogen signaling pathway_Homo sapiens_hsa049151.13382681
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13213596
40Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.09989512
41Cardiac muscle contraction_Homo sapiens_hsa042601.08623173
42Gap junction_Homo sapiens_hsa045401.07761717
43Vitamin B6 metabolism_Homo sapiens_hsa007501.05986597
44Nitrogen metabolism_Homo sapiens_hsa009101.04128443
45Carbohydrate digestion and absorption_Homo sapiens_hsa049731.02536602
46Pancreatic secretion_Homo sapiens_hsa049720.99910318
47Glioma_Homo sapiens_hsa052140.95866799
48Vascular smooth muscle contraction_Homo sapiens_hsa042700.95546584
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.94765690
50Vibrio cholerae infection_Homo sapiens_hsa051100.93808496
51Phenylalanine metabolism_Homo sapiens_hsa003600.93145145
52Thyroid hormone synthesis_Homo sapiens_hsa049180.87699816
53Bile secretion_Homo sapiens_hsa049760.86804519
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.86366006
55Notch signaling pathway_Homo sapiens_hsa043300.86061097
56Melanogenesis_Homo sapiens_hsa049160.83677030
57Axon guidance_Homo sapiens_hsa043600.80641667
58Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77064103
59Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76316490
60Hippo signaling pathway_Homo sapiens_hsa043900.75561959
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74672999
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74131868
63Tight junction_Homo sapiens_hsa045300.74105713
64Glucagon signaling pathway_Homo sapiens_hsa049220.73989287
65Fatty acid biosynthesis_Homo sapiens_hsa000610.73571968
66Prion diseases_Homo sapiens_hsa050200.72441192
67Renal cell carcinoma_Homo sapiens_hsa052110.70737979
68Dilated cardiomyopathy_Homo sapiens_hsa054140.70154742
69ErbB signaling pathway_Homo sapiens_hsa040120.68971541
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68311302
71Thyroid cancer_Homo sapiens_hsa052160.68176576
72Wnt signaling pathway_Homo sapiens_hsa043100.67104239
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.66998820
74Basal cell carcinoma_Homo sapiens_hsa052170.66776207
75Dorso-ventral axis formation_Homo sapiens_hsa043200.66100305
76Choline metabolism in cancer_Homo sapiens_hsa052310.63150712
77Circadian rhythm_Homo sapiens_hsa047100.61266856
78VEGF signaling pathway_Homo sapiens_hsa043700.60834268
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.59274523
80Alzheimers disease_Homo sapiens_hsa050100.58977081
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58843054
82Hedgehog signaling pathway_Homo sapiens_hsa043400.58010825
83Prolactin signaling pathway_Homo sapiens_hsa049170.57869629
84MAPK signaling pathway_Homo sapiens_hsa040100.54890181
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53745477
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.53456651
87Melanoma_Homo sapiens_hsa052180.53339810
88Sulfur relay system_Homo sapiens_hsa041220.52358933
89beta-Alanine metabolism_Homo sapiens_hsa004100.51464356
90Fatty acid metabolism_Homo sapiens_hsa012120.51351922
91Steroid biosynthesis_Homo sapiens_hsa001000.50730661
92Inositol phosphate metabolism_Homo sapiens_hsa005620.49698799
93Oocyte meiosis_Homo sapiens_hsa041140.46642479
94Arginine biosynthesis_Homo sapiens_hsa002200.46423773
95Rap1 signaling pathway_Homo sapiens_hsa040150.45583547
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44548598
97mTOR signaling pathway_Homo sapiens_hsa041500.44091332
98Acute myeloid leukemia_Homo sapiens_hsa052210.43916225
99Insulin signaling pathway_Homo sapiens_hsa049100.43694145
100Insulin resistance_Homo sapiens_hsa049310.43533220
1012-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.43256276
102Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.43218581
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40877963
104Ras signaling pathway_Homo sapiens_hsa040140.40539075
105Endocytosis_Homo sapiens_hsa041440.38030622
106Mineral absorption_Homo sapiens_hsa049780.36932650
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.36729886
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36113103
109Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35359340
110Oxidative phosphorylation_Homo sapiens_hsa001900.33950700
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33546127
112African trypanosomiasis_Homo sapiens_hsa051430.32841737
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.32416924
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31836387
115Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.31814632
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31077784
117Ovarian steroidogenesis_Homo sapiens_hsa049130.25961360
118Maturity onset diabetes of the young_Homo sapiens_hsa049500.25409258
119Non-small cell lung cancer_Homo sapiens_hsa052230.25396142
120Glycerolipid metabolism_Homo sapiens_hsa005610.25185908
121Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24991686
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.24644302
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.23624919
124Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.22312177
125Endometrial cancer_Homo sapiens_hsa052130.21380402

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »