RTP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* protein insertion into membrane (GO:0051205)7.82761023
2adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)7.48115116
3protein polyglutamylation (GO:0018095)7.32493961
4regulation of female gonad development (GO:2000194)7.30254719
5regulation of chromatin binding (GO:0035561)6.60927730
6regulation of cilium movement (GO:0003352)6.41220646
7intraciliary transport (GO:0042073)6.25582097
8axoneme assembly (GO:0035082)5.80919921
9axonemal dynein complex assembly (GO:0070286)5.37415949
10cilium morphogenesis (GO:0060271)5.32618782
11phosphorelay signal transduction system (GO:0000160)5.03323252
12pyrimidine nucleobase catabolic process (GO:0006208)4.97256087
13innate immune response in mucosa (GO:0002227)4.90572313
14auditory receptor cell differentiation (GO:0042491)4.89615032
15detection of calcium ion (GO:0005513)4.88081344
16antibacterial humoral response (GO:0019731)4.86468819
17cilium movement (GO:0003341)4.74003365
18dopamine receptor signaling pathway (GO:0007212)4.48325104
19antimicrobial humoral response (GO:0019730)4.47519734
20neuron cell-cell adhesion (GO:0007158)4.46869103
21negative regulation of cytosolic calcium ion concentration (GO:0051481)4.43261051
22phenol-containing compound catabolic process (GO:0019336)4.39343792
23adipose tissue development (GO:0060612)4.36872781
24chaperone-mediated protein transport (GO:0072321)4.26308731
25regulation of DNA methylation (GO:0044030)4.23383538
26cellular response to glucagon stimulus (GO:0071377)4.20909451
27natural killer cell mediated cytotoxicity (GO:0042267)4.16712743
28natural killer cell mediated immunity (GO:0002228)4.16712743
29behavioral response to nicotine (GO:0035095)4.16024578
30mucosal immune response (GO:0002385)4.12368248
31microtubule severing (GO:0051013)4.10870928
32epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.09019232
33behavioral response to cocaine (GO:0048148)4.05870594
34gamma-aminobutyric acid transport (GO:0015812)4.02251440
35organ or tissue specific immune response (GO:0002251)3.91134593
36microtubule bundle formation (GO:0001578)3.89463438
37nucleobase catabolic process (GO:0046113)3.88211453
38activation of protein kinase A activity (GO:0034199)3.88127771
39protein localization to synapse (GO:0035418)3.87537996
40positive regulation of gastrulation (GO:2000543)3.85517088
41somite rostral/caudal axis specification (GO:0032525)3.83813731
42regulation of microtubule-based movement (GO:0060632)3.78595267
43neurotransmitter-gated ion channel clustering (GO:0072578)3.74300259
44sensory perception of taste (GO:0050909)3.67365008
45photoreceptor cell maintenance (GO:0045494)3.66632322
46epithelial cilium movement (GO:0003351)3.63765428
47positive regulation of synapse assembly (GO:0051965)3.62892456
48regulation of calcium ion-dependent exocytosis (GO:0017158)3.60729852
49regulation of sodium ion transmembrane transporter activity (GO:2000649)3.56163461
50neuron remodeling (GO:0016322)3.55972607
51response to gravity (GO:0009629)3.52727966
52axonal fasciculation (GO:0007413)3.51503600
53response to caffeine (GO:0031000)3.51165499
54presynaptic membrane organization (GO:0097090)3.49639970
55presynaptic membrane assembly (GO:0097105)3.46043599
56cellular copper ion homeostasis (GO:0006878)3.44976816
57vocalization behavior (GO:0071625)3.44856635
58glycogen catabolic process (GO:0005980)3.44850905
59regulation of heart rate by cardiac conduction (GO:0086091)3.40937305
60G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.39189894
61ventricular system development (GO:0021591)3.37801034
62negative regulation of microtubule polymerization (GO:0031115)3.36786647
63hormone catabolic process (GO:0042447)3.36323140
64retinal cone cell development (GO:0046549)3.36088343
65transmission of nerve impulse (GO:0019226)3.35718615
66dendritic spine morphogenesis (GO:0060997)3.35358691
67regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.34645529
68olfactory bulb development (GO:0021772)3.30709474
69cAMP biosynthetic process (GO:0006171)3.30040117
70magnesium ion transport (GO:0015693)3.24933302
71mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.24867263
72response to glucagon (GO:0033762)3.24852634
73neuron recognition (GO:0008038)3.24136775
74potassium ion transmembrane transport (GO:0071805)3.23928789
75cellular potassium ion transport (GO:0071804)3.23928789
76glucan catabolic process (GO:0009251)3.21726063
77positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.20888050
78regulation of cell communication by electrical coupling (GO:0010649)3.18418180
79negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.16063546
80ATP synthesis coupled proton transport (GO:0015986)3.15451012
81energy coupled proton transport, down electrochemical gradient (GO:0015985)3.15451012
82response to amphetamine (GO:0001975)3.13396027
83secondary heart field specification (GO:0003139)3.13202914
84heart field specification (GO:0003128)3.13202914
85synaptic vesicle maturation (GO:0016188)3.13013437
86membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.12705226
87cilium assembly (GO:0042384)3.12584153
88ER overload response (GO:0006983)3.12347918
89regulation of histone H3-K9 methylation (GO:0051570)3.11112965
90single strand break repair (GO:0000012)3.10114125
91regulation of synapse structural plasticity (GO:0051823)3.07975448
92positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.07930598
93mating behavior (GO:0007617)3.07541297
94glutamate secretion (GO:0014047)3.05209036
95cell migration involved in gastrulation (GO:0042074)3.05206301
96melanosome transport (GO:0032402)3.04344683
97negative regulation of histone methylation (GO:0031061)3.04297829
98postsynaptic membrane organization (GO:0001941)3.02653074
99peptidyl-lysine dimethylation (GO:0018027)3.01967217
100sensory perception of smell (GO:0007608)22.9404797
101regulation of sodium ion transmembrane transport (GO:1902305)2.99913413
102atrial cardiac muscle cell action potential (GO:0086014)2.99778797
103cellular response to electrical stimulus (GO:0071257)2.99689461
104positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.95003751
105cilium organization (GO:0044782)2.94325957
106peptidyl-glutamic acid modification (GO:0018200)2.91591390
107melanosome localization (GO:0032400)2.90173382
108positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.89606598
109thyroid hormone generation (GO:0006590)2.89178855
110potassium ion transport (GO:0006813)2.88733481
111hair cell differentiation (GO:0035315)2.88664337
112negative regulation of astrocyte differentiation (GO:0048712)2.88332538
113cellular polysaccharide catabolic process (GO:0044247)2.87881595
114pigment granule transport (GO:0051904)2.87477747
115negative regulation of complement activation (GO:0045916)2.87373637
116protein neddylation (GO:0045116)2.87100895
117ADP metabolic process (GO:0046031)2.87087151
118establishment of melanosome localization (GO:0032401)2.85001212
119connective tissue development (GO:0061448)2.83570908
120mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.83441875
121mitochondrial respiratory chain complex I assembly (GO:0032981)2.83441875
122NADH dehydrogenase complex assembly (GO:0010257)2.83441875
123meiotic cell cycle (GO:0051321)2.82605790
124snRNA transcription (GO:0009301)2.82521898
125regulation of female receptivity (GO:0045924)2.82442035
126glutamate receptor signaling pathway (GO:0007215)2.82086492
127cardiac conduction (GO:0061337)2.81003143
128cellular modified amino acid catabolic process (GO:0042219)2.80971129
129protein heterotetramerization (GO:0051290)2.80805602
130calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.80062372
131brain morphogenesis (GO:0048854)2.78668504
132regulation of protein kinase A signaling (GO:0010738)2.77686564
133regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.77506291
134membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.76599262
135inner ear receptor cell differentiation (GO:0060113)2.76398724
136piRNA metabolic process (GO:0034587)2.76300938
137membrane repolarization during action potential (GO:0086011)2.76223392
138pigment granule localization (GO:0051875)2.76005285
139sequestering of actin monomers (GO:0042989)2.75325675
140calcium-mediated signaling using intracellular calcium source (GO:0035584)2.74059615
141neurofilament cytoskeleton organization (GO:0060052)2.73240244
142positive regulation of action potential (GO:0045760)2.73091439
143left/right axis specification (GO:0070986)2.71453817
144pyrimidine nucleotide catabolic process (GO:0006244)2.70842623
145regulation of gene silencing by RNA (GO:0060966)2.70332948
146regulation of posttranscriptional gene silencing (GO:0060147)2.70332948
147regulation of gene silencing by miRNA (GO:0060964)2.70332948
148potassium ion homeostasis (GO:0055075)2.69829699
149establishment of pigment granule localization (GO:0051905)2.69780203
150kidney morphogenesis (GO:0060993)2.69513090
151polysaccharide catabolic process (GO:0000272)2.68717549
152synaptic vesicle docking involved in exocytosis (GO:0016081)2.67704784
153regulation of development, heterochronic (GO:0040034)2.66981642
154specification of organ identity (GO:0010092)2.66766963
155negative regulation of glycogen biosynthetic process (GO:0045719)2.66646567
156negative regulation of transcription regulatory region DNA binding (GO:2000678)2.66583253
157hydrogen ion transmembrane transport (GO:1902600)2.65002831
158pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.60744127
159regulation of acrosome reaction (GO:0060046)2.60570646
160cell proliferation in forebrain (GO:0021846)2.58455198
161DNA methylation involved in gamete generation (GO:0043046)2.58189132
162startle response (GO:0001964)2.57284667
163layer formation in cerebral cortex (GO:0021819)2.56682165
164establishment of protein localization to mitochondrial membrane (GO:0090151)2.55293975
165female mating behavior (GO:0060180)2.55188610
166establishment of mitochondrion localization (GO:0051654)2.55014775
167dendrite morphogenesis (GO:0048813)2.54726189
168negative regulation of synaptic transmission, GABAergic (GO:0032229)2.54341543
169ionotropic glutamate receptor signaling pathway (GO:0035235)2.52143235
170regulation of short-term neuronal synaptic plasticity (GO:0048172)2.51921896
171positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.51852883
172synapse assembly (GO:0007416)2.51509331
173synaptic transmission, glutamatergic (GO:0035249)2.50222876
174regulation of timing of cell differentiation (GO:0048505)2.49734235
175cell migration in hindbrain (GO:0021535)2.46996665
176regulation of dendritic spine morphogenesis (GO:0061001)2.44236539
177protein complex biogenesis (GO:0070271)2.42459563
178electron transport chain (GO:0022900)2.42338405
179adult walking behavior (GO:0007628)2.41593057
180glycine transport (GO:0015816)2.40320629
181positive regulation of potassium ion transmembrane transport (GO:1901381)2.40100885
182protein localization to kinetochore (GO:0034501)2.39714682
183positive regulation of synapse maturation (GO:0090129)2.38156844
184hippocampus development (GO:0021766)2.37574509
185respiratory electron transport chain (GO:0022904)2.37543602
186thyroid hormone metabolic process (GO:0042403)2.36528927
187regulation of translation, ncRNA-mediated (GO:0045974)2.34592857
188sensory perception of chemical stimulus (GO:0007606)13.7682579
189protein localization to cilium (GO:0061512)10.6578725

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.34506063
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.90721757
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.86893795
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.51011010
5DROSHA_22980978_ChIP-Seq_HELA_Human3.05323633
6ZNF263_19887448_ChIP-Seq_K562_Human2.94783421
7GBX2_23144817_ChIP-Seq_PC3_Human2.85267525
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.70977039
9ZNF274_21170338_ChIP-Seq_K562_Hela2.65918380
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.56919596
11TAF15_26573619_Chip-Seq_HEK293_Human2.31149762
12ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse2.22725572
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.05249251
14IRF1_19129219_ChIP-ChIP_H3396_Human2.04558139
15* BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.95899338
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.94162678
17SALL1_21062744_ChIP-ChIP_HESCs_Human1.91945031
18EZH2_18974828_ChIP-Seq_MESCs_Mouse1.90520290
19RNF2_18974828_ChIP-Seq_MESCs_Mouse1.90520290
20CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.89711651
21BMI1_23680149_ChIP-Seq_NPCS_Mouse1.89026063
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.80435090
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.78669269
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.77293358
25AHR_22903824_ChIP-Seq_MCF-7_Human1.72552552
26GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.71075593
27TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.70998980
28POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.70998980
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.69756373
30VDR_22108803_ChIP-Seq_LS180_Human1.68593626
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.67368091
32SRY_22984422_ChIP-ChIP_TESTIS_Rat1.66112780
33E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.60494698
34LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59824187
35SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.59812407
36JARID2_20064375_ChIP-Seq_MESCs_Mouse1.57772116
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.55538644
38RNF2_27304074_Chip-Seq_NSC_Mouse1.55438433
39KDM2B_26808549_Chip-Seq_K562_Human1.53524075
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48260152
41* REST_21632747_ChIP-Seq_MESCs_Mouse1.44914713
42MTF2_20144788_ChIP-Seq_MESCs_Mouse1.43005422
43FUS_26573619_Chip-Seq_HEK293_Human1.41549711
44NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.41521382
45OCT4_20526341_ChIP-Seq_ESCs_Human1.39754495
46ARNT_22903824_ChIP-Seq_MCF-7_Human1.38994321
47ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.38858742
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38714966
49TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.38610514
50SUZ12_27294783_Chip-Seq_ESCs_Mouse1.38279999
51HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.36759067
52SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.36291050
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35666176
54PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35310784
55JARID2_20075857_ChIP-Seq_MESCs_Mouse1.33268975
56SMAD4_21741376_ChIP-Seq_EPCs_Human1.31780021
57SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.29456597
58SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.28013331
59SOX2_16153702_ChIP-ChIP_HESCs_Human1.25057148
60P300_19829295_ChIP-Seq_ESCs_Human1.24297537
61RARB_27405468_Chip-Seq_BRAIN_Mouse1.24279473
62IKZF1_21737484_ChIP-ChIP_HCT116_Human1.23933563
63RNF2_27304074_Chip-Seq_ESCs_Mouse1.23730739
64PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.23617174
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.23560015
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23349076
67* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.23121980
68RBPJ_22232070_ChIP-Seq_NCS_Mouse1.20509782
69TDRD3_21172665_ChIP-Seq_MCF-7_Human1.20472399
70RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19736232
71EZH2_27294783_Chip-Seq_ESCs_Mouse1.19339866
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18815353
73* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.18241516
74SMAD4_21799915_ChIP-Seq_A2780_Human1.16698804
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15910333
76RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.13908940
77GATA3_27048872_Chip-Seq_THYMUS_Human1.13800485
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13251175
79KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.11524849
80ESR1_20079471_ChIP-ChIP_T-47D_Human1.11403697
81RING1B_27294783_Chip-Seq_ESCs_Mouse1.10492725
82EST1_17652178_ChIP-ChIP_JURKAT_Human1.10135483
83TP53_22573176_ChIP-Seq_HFKS_Human1.10050554
84KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.09859136
85PRDM14_20953172_ChIP-Seq_ESCs_Human1.09719663
86ZFP57_27257070_Chip-Seq_ESCs_Mouse1.09665966
87CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.09420777
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07072818
89NANOG_16153702_ChIP-ChIP_HESCs_Human1.06922907
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06459331
91SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.06064326
92IGF1R_20145208_ChIP-Seq_DFB_Human1.05935958
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.04538121
94EWS_26573619_Chip-Seq_HEK293_Human1.04433356
95ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03596185
96NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.02551368
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.02372484
98SMAD3_21741376_ChIP-Seq_EPCs_Human1.01634788
99SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01613841
100REST_18959480_ChIP-ChIP_MESCs_Mouse1.00107885
101MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99523980
102CBP_20019798_ChIP-Seq_JUKART_Human0.98735528
103IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.98735528
104CDX2_22108803_ChIP-Seq_LS180_Human0.97736535
105NANOG_20526341_ChIP-Seq_ESCs_Human0.97597406
106RUNX2_22187159_ChIP-Seq_PCA_Human0.97513569
107SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.96769974
108GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.96043022
109GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95913928
110SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95810747
111SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.95796878
112SOX2_27498859_Chip-Seq_STOMACH_Mouse0.95720009
113GABP_17652178_ChIP-ChIP_JURKAT_Human0.95275234
114AR_25329375_ChIP-Seq_VCAP_Human0.94268877
115EZH2_27304074_Chip-Seq_ESCs_Mouse0.94154736
116NCOR_22424771_ChIP-Seq_293T_Human0.93888639
117E2F1_20622854_ChIP-Seq_HELA_Human0.93810748
118PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.93102392
119MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91938095
120CTCF_20526341_ChIP-Seq_ESCs_Human0.91635541
121SMAD3_21741376_ChIP-Seq_ESCs_Human0.91394651
122IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.91385169
123BCOR_27268052_Chip-Seq_Bcells_Human0.91220103
124STAT3_23295773_ChIP-Seq_U87_Human0.91186264
125* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.90722552
126PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.90612729
127RING1B_27294783_Chip-Seq_NPCs_Mouse0.90132834
128TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.89563557
129CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.89222402
130* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.89082180
131NOTCH1_21737748_ChIP-Seq_TLL_Human0.88707225
132MYC_18940864_ChIP-ChIP_HL60_Human0.88279207
133TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.87430241
134TP53_20018659_ChIP-ChIP_R1E_Mouse0.87107742
135SMAD4_21741376_ChIP-Seq_HESCs_Human0.87012497
136GF1_26923725_Chip-Seq_HPCs_Mouse0.86365081
137POU3F2_20337985_ChIP-ChIP_501MEL_Human0.85967814
138TCF4_23295773_ChIP-Seq_U87_Human0.85675411
139MYC_19829295_ChIP-Seq_ESCs_Human0.85612140
140PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85485518
141TBX3_20139965_ChIP-Seq_ESCs_Mouse0.85481405
142LXR_22292898_ChIP-Seq_THP-1_Human0.85267496
143TCF4_22108803_ChIP-Seq_LS180_Human0.84674305
144STAT1_20625510_ChIP-Seq_HELA_Human0.84673018
145TBX3_20139965_ChIP-Seq_MESCs_Mouse0.84643739
146EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.84459023
147E2F1_17053090_ChIP-ChIP_MCF-7_Human0.84272607
148* AR_19668381_ChIP-Seq_PC3_Human0.82563676
149EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.82110426
150SOX2_19829295_ChIP-Seq_ESCs_Human0.82088986
151NANOG_19829295_ChIP-Seq_ESCs_Human0.82088986
152MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.81449518
153FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.81156227
154GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80384943

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008789_abnormal_olfactory_epithelium4.50123144
2MP0005499_abnormal_olfactory_system4.14185750
3MP0005394_taste/olfaction_phenotype4.14185750
4MP0003122_maternal_imprinting4.00851947
5MP0003121_genomic_imprinting3.27678482
6MP0008877_abnormal_DNA_methylation3.13185893
7MP0006292_abnormal_olfactory_placode3.00576992
8MP0005645_abnormal_hypothalamus_physiol2.97013819
9MP0001485_abnormal_pinna_reflex2.62334993
10MP0003806_abnormal_nucleotide_metabolis2.60195998
11MP0003787_abnormal_imprinting2.53928140
12MP0003718_maternal_effect2.52232022
13MP0002184_abnormal_innervation2.21543328
14MP0000566_synostosis2.16863848
15MP0003890_abnormal_embryonic-extraembry2.09918550
16MP0001984_abnormal_olfaction15.5172241
17MP0003878_abnormal_ear_physiology1.93318522
18MP0005377_hearing/vestibular/ear_phenot1.93318522
19MP0002160_abnormal_reproductive_system1.84996755
20MP0001968_abnormal_touch/_nociception1.84267387
21MP0001529_abnormal_vocalization1.78426487
22MP0001986_abnormal_taste_sensitivity1.72909530
23MP0002928_abnormal_bile_duct1.72717705
24MP0003136_yellow_coat_color1.71391803
25MP0002822_catalepsy1.69363249
26MP0001542_abnormal_bone_strength1.60552133
27MP0002736_abnormal_nociception_after1.58844984
28MP0005084_abnormal_gallbladder_morpholo1.57357584
29MP0005367_renal/urinary_system_phenotyp1.56652452
30MP0000516_abnormal_urinary_system1.56652452
31MP0004142_abnormal_muscle_tone1.46836454
32MP0005083_abnormal_biliary_tract1.43855380
33MP0002234_abnormal_pharynx_morphology1.43334665
34MP0010030_abnormal_orbit_morphology1.40835932
35MP0002734_abnormal_mechanical_nocicepti1.39298468
36MP0002752_abnormal_somatic_nervous1.38572307
37MP0003252_abnormal_bile_duct1.38204807
38MP0002733_abnormal_thermal_nociception1.35621944
39MP0009046_muscle_twitch1.33802293
40MP0000372_irregular_coat_pigmentation1.33312196
41MP0002557_abnormal_social/conspecific_i1.29998682
42MP0001486_abnormal_startle_reflex1.29814186
43MP0001440_abnormal_grooming_behavior1.28527712
44MP0005646_abnormal_pituitary_gland1.26128934
45MP0003119_abnormal_digestive_system1.25108044
46MP0000955_abnormal_spinal_cord1.22632344
47MP0004885_abnormal_endolymph1.20367547
48MP0002272_abnormal_nervous_system1.19263872
49MP0002638_abnormal_pupillary_reflex1.16683688
50MP0003315_abnormal_perineum_morphology1.14864585
51MP0003880_abnormal_central_pattern1.14718855
52MP0002653_abnormal_ependyma_morphology1.14211479
53MP0003011_delayed_dark_adaptation1.14034495
54MP0004270_analgesia1.11133491
55MP0002233_abnormal_nose_morphology1.10489614
56MP0001501_abnormal_sleep_pattern1.09323206
57MP0003635_abnormal_synaptic_transmissio1.07077665
58MP0002882_abnormal_neuron_morphology1.06035461
59MP0003283_abnormal_digestive_organ1.05333096
60MP0003937_abnormal_limbs/digits/tail_de1.03853394
61MP0000778_abnormal_nervous_system1.03343230
62MP0005410_abnormal_fertilization1.01461940
63MP0010234_abnormal_vibrissa_follicle1.01074165
64MP0005389_reproductive_system_phenotype0.96095941
65MP0006276_abnormal_autonomic_nervous0.96039253
66MP0003938_abnormal_ear_development0.95966316
67MP0009379_abnormal_foot_pigmentation0.95641893
68MP0004924_abnormal_behavior0.95403621
69MP0005386_behavior/neurological_phenoty0.95403621
70MP0004145_abnormal_muscle_electrophysio0.94726880
71MP0005551_abnormal_eye_electrophysiolog0.90272777
72MP0008058_abnormal_DNA_repair0.89701844
73MP0009333_abnormal_splenocyte_physiolog0.88792860
74MP0002876_abnormal_thyroid_physiology0.88139741
75MP0004742_abnormal_vestibular_system0.85676963
76MP0004811_abnormal_neuron_physiology0.85459654
77MP0005423_abnormal_somatic_nervous0.85443326
78MP0008995_early_reproductive_senescence0.84692142
79MP0002877_abnormal_melanocyte_morpholog0.84490559
80MP0001293_anophthalmia0.83050175
81MP0004858_abnormal_nervous_system0.83021904
82MP0002152_abnormal_brain_morphology0.81435006
83MP0002210_abnormal_sex_determination0.81423338
84MP0003693_abnormal_embryo_hatching0.79976039
85MP0001929_abnormal_gametogenesis0.79495418
86MP0004147_increased_porphyrin_level0.79353534
87MP0002063_abnormal_learning/memory/cond0.78935834
88MP0001919_abnormal_reproductive_system0.77282502
89MP0003183_abnormal_peptide_metabolism0.77142768
90MP0000003_abnormal_adipose_tissue0.77084892
91MP0002229_neurodegeneration0.75310549
92MP0000647_abnormal_sebaceous_gland0.75150681
93MP0003567_abnormal_fetal_cardiomyocyte0.74924274
94MP0001188_hyperpigmentation0.74348323
95MP0002909_abnormal_adrenal_gland0.73676544
96MP0003123_paternal_imprinting0.73058368
97MP0005253_abnormal_eye_physiology0.72957437
98MP0003698_abnormal_male_reproductive0.72636384
99MP0005187_abnormal_penis_morphology0.66130000
100MP0004859_abnormal_synaptic_plasticity0.65895568
101MP0002572_abnormal_emotion/affect_behav0.65072692
102MP0001970_abnormal_pain_threshold0.63899381
103MP0003634_abnormal_glial_cell0.63725321
104MP0002102_abnormal_ear_morphology0.63652578
105MP0008875_abnormal_xenobiotic_pharmacok0.62026576
106MP0003942_abnormal_urinary_system0.61321026
107MP0001963_abnormal_hearing_physiology0.60607673
108MP0000026_abnormal_inner_ear0.60297851
109MP0000631_abnormal_neuroendocrine_gland0.57244260
110MP0000538_abnormal_urinary_bladder0.55014851
111MP0002067_abnormal_sensory_capabilities0.54894646
112MP0004133_heterotaxia0.53177617
113MP0003861_abnormal_nervous_system0.52497248
114MP0002896_abnormal_bone_mineralization0.51015076
115MP0005174_abnormal_tail_pigmentation0.48787524
116MP0005195_abnormal_posterior_eye0.48305255
117MP0002064_seizures0.48165388
118MP0003879_abnormal_hair_cell0.47573106
119MP0002938_white_spotting0.47571040
120MP0005584_abnormal_enzyme/coenzyme_acti0.45991155
121MP0004510_myositis0.45702464
122MP0002751_abnormal_autonomic_nervous0.43853640
123MP0006036_abnormal_mitochondrial_physio0.43304651
124MP0008874_decreased_physiological_sensi0.42554834
125MP0009765_abnormal_xenobiotic_induced0.40728573
126MP0003763_abnormal_thymus_physiology0.40059472
127MP0001270_distended_abdomen0.39626537
128MP0005220_abnormal_exocrine_pancreas0.39339376
129MP0006035_abnormal_mitochondrial_morpho0.36366873
130MP0003633_abnormal_nervous_system0.36050719
131MP0000049_abnormal_middle_ear0.35520589
132MP0003075_altered_response_to0.35147026
133MP0009745_abnormal_behavioral_response0.33919491
134MP0005058_abnormal_lysosome_morphology0.32538038
135MP0004782_abnormal_surfactant_physiolog0.32343355
136MP0002066_abnormal_motor_capabilities/c0.32180123
137MP0001299_abnormal_eye_distance/0.30130481
138MP0002735_abnormal_chemical_nociception0.29985118
139MP0010770_preweaning_lethality0.29829975
140MP0002082_postnatal_lethality0.29829975
141MP0005365_abnormal_bile_salt0.29657999
142MP0002092_abnormal_eye_morphology0.28827679
143MP0002132_abnormal_respiratory_system0.28668208
144MP0005165_increased_susceptibility_to0.27855691
145MP0005623_abnormal_meninges_morphology0.27811497
146MP0010769_abnormal_survival0.25636635
147MP0002081_perinatal_lethality0.25391282

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)9.23083518
2Retinal dysplasia (HP:0007973)7.74285843
3Abnormal respiratory motile cilium physiology (HP:0012261)6.70899483
4Abnormality of macular pigmentation (HP:0008002)6.48895668
5Rhinitis (HP:0012384)6.24321509
6Bifid tongue (HP:0010297)5.73633433
7Abnormality of midbrain morphology (HP:0002418)5.67381935
8Molar tooth sign on MRI (HP:0002419)5.67381935
9Limb dystonia (HP:0002451)5.40488835
10Chronic bronchitis (HP:0004469)5.33235165
11Abnormal ciliary motility (HP:0012262)5.01223137
12Palpitations (HP:0001962)4.76273541
13Abnormal respiratory motile cilium morphology (HP:0005938)4.66110109
14Abnormal respiratory epithelium morphology (HP:0012253)4.66110109
15Dysphonia (HP:0001618)4.02671095
16Abolished electroretinogram (ERG) (HP:0000550)3.87862406
17Gait imbalance (HP:0002141)3.85722467
18Bony spicule pigmentary retinopathy (HP:0007737)3.85417784
19Septo-optic dysplasia (HP:0100842)3.81130370
20Congenital primary aphakia (HP:0007707)3.77861143
21Short nail (HP:0001799)3.76823022
22Abnormality of dentin (HP:0010299)3.75706797
23Abnormality of the labia minora (HP:0012880)3.75231709
24Supernumerary spleens (HP:0009799)3.69719114
25Nephrogenic diabetes insipidus (HP:0009806)3.67310169
26Medial flaring of the eyebrow (HP:0010747)3.60273268
27Hypothermia (HP:0002045)3.56416340
28Pancreatic fibrosis (HP:0100732)3.47787810
29Occipital encephalocele (HP:0002085)3.46774620
30True hermaphroditism (HP:0010459)3.43430481
31Atonic seizures (HP:0010819)3.37306076
32Postaxial hand polydactyly (HP:0001162)3.36691507
33Bronchiectasis (HP:0002110)3.30854646
34Nephronophthisis (HP:0000090)3.27127447
35Chronic hepatic failure (HP:0100626)3.22953120
36Hypochromic microcytic anemia (HP:0004840)3.17040867
37Anosmia (HP:0000458)3.16620746
38Syncope (HP:0001279)3.00876985
39Abdominal situs inversus (HP:0003363)3.00242501
40Abnormality of abdominal situs (HP:0011620)3.00242501
41Cystic liver disease (HP:0006706)3.00217201
42Torticollis (HP:0000473)2.97329138
43Poor coordination (HP:0002370)2.95359357
44Vaginal atresia (HP:0000148)2.94674383
45Poikilocytosis (HP:0004447)2.89436006
46Central scotoma (HP:0000603)2.86793547
47Genital tract atresia (HP:0001827)2.84874909
48Pancreatic cysts (HP:0001737)2.81608543
49Absent septum pellucidum (HP:0001331)2.80701485
50Abnormality of sodium homeostasis (HP:0010931)2.76004276
51Abnormality of permanent molar morphology (HP:0011071)2.73618124
52Abnormality of the dental root (HP:0006486)2.73618124
53Taurodontia (HP:0000679)2.73618124
54Febrile seizures (HP:0002373)2.72649836
55Oculomotor apraxia (HP:0000657)2.71169020
56Focal seizures (HP:0007359)2.65259522
57Abnormality of molar (HP:0011077)2.58826656
58Abnormality of molar morphology (HP:0011070)2.58826656
59Osteomalacia (HP:0002749)2.56167144
60Cortical dysplasia (HP:0002539)2.56072922
61Dynein arm defect of respiratory motile cilia (HP:0012255)2.52777520
62Absent/shortened dynein arms (HP:0200106)2.52777520
63Asplenia (HP:0001746)2.52566238
64Craniofacial dystonia (HP:0012179)2.52372693
65Aplasia/Hypoplasia of the lens (HP:0008063)2.51521850
66Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.50844097
67Median cleft lip (HP:0000161)2.47080951
68Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.46477353
69Focal motor seizures (HP:0011153)2.44820753
70Optic nerve hypoplasia (HP:0000609)2.44179330
71Growth hormone deficiency (HP:0000824)2.43163303
72Aplasia/Hypoplasia of the spleen (HP:0010451)2.43039295
73Complete atrioventricular canal defect (HP:0001674)2.42789734
74Abnormality of the renal medulla (HP:0100957)2.40112095
75Fetal akinesia sequence (HP:0001989)2.38391415
76Abnormality of the dental pulp (HP:0006479)2.37030131
77Birth length less than 3rd percentile (HP:0003561)2.36741855
78Abnormal biliary tract physiology (HP:0012439)2.35878325
79Bile duct proliferation (HP:0001408)2.35878325
80Constricted visual fields (HP:0001133)2.34926858
81Myokymia (HP:0002411)2.32854832
82Spastic tetraplegia (HP:0002510)2.32224336
83Pendular nystagmus (HP:0012043)2.31992012
84Absent rod-and cone-mediated responses on ERG (HP:0007688)2.31940659
85Prolonged QT interval (HP:0001657)2.30725987
86Furrowed tongue (HP:0000221)2.30077673
87Focal dystonia (HP:0004373)2.29928254
88Hypoplastic female external genitalia (HP:0012815)2.28981975
89Progressive cerebellar ataxia (HP:0002073)2.27047715
90Absent eyebrow (HP:0002223)2.26371557
91Impulsivity (HP:0100710)2.26245090
92Oligodactyly (hands) (HP:0001180)2.26171462
93Labial hypoplasia (HP:0000066)2.26027864
94Broad-based gait (HP:0002136)2.25749726
95Drooling (HP:0002307)2.24683749
96Abnormality of the septum pellucidum (HP:0007375)2.24378333
973-Methylglutaconic aciduria (HP:0003535)2.22946990
98Renal hypoplasia (HP:0000089)2.22776418
99Inability to walk (HP:0002540)2.21125956
100Hypsarrhythmia (HP:0002521)2.20637155
101Lissencephaly (HP:0001339)2.18972165
102Epileptiform EEG discharges (HP:0011182)2.18453556
103Sudden death (HP:0001699)2.18439611
104Poor suck (HP:0002033)2.18275535
105Tubulointerstitial nephritis (HP:0001970)2.17805052
106Aplasia/Hypoplasia of the tongue (HP:0010295)2.15118433
107Absence seizures (HP:0002121)2.14490518
108Hyperglycinemia (HP:0002154)2.14133438
109Polyphagia (HP:0002591)2.13982069
110EEG with generalized epileptiform discharges (HP:0011198)2.10530793
111Sclerocornea (HP:0000647)2.09569613
112Chronic sinusitis (HP:0011109)2.07873762
113Retinitis pigmentosa (HP:0000510)2.07315388
114Amblyopia (HP:0000646)2.05256093
115Thyroid-stimulating hormone excess (HP:0002925)2.04483452
116Tubular atrophy (HP:0000092)2.00563219
117Cerebral hypomyelination (HP:0006808)2.00556986
118Excessive salivation (HP:0003781)2.00054894
119Urinary urgency (HP:0000012)1.99131409
120Recurrent otitis media (HP:0000403)1.99076283
121Xerostomia (HP:0000217)1.98431241
122Aganglionic megacolon (HP:0002251)1.97111368
123Anomalous pulmonary venous return (HP:0010772)1.96366898
124Aplasia/Hypoplasia of the brainstem (HP:0007362)1.96249717
125Hypoplasia of the brainstem (HP:0002365)1.96249717
126Posterior embryotoxon (HP:0000627)1.92952999
127Agitation (HP:0000713)1.92536691
128Abnormality of cells of the erythroid lineage (HP:0012130)1.91920615
129Congenital hepatic fibrosis (HP:0002612)1.91393847
130Congenital malformation of the right heart (HP:0011723)1.89675237
131Double outlet right ventricle (HP:0001719)1.89675237
132Failure to thrive in infancy (HP:0001531)1.88102964
133Polydipsia (HP:0001959)1.87715348
134Abnormal drinking behavior (HP:0030082)1.87715348
135Tubulointerstitial fibrosis (HP:0005576)1.86981334
136Abnormal rod and cone electroretinograms (HP:0008323)1.86599275
137Bronchitis (HP:0012387)1.86050059
138Male pseudohermaphroditism (HP:0000037)1.85919978
139Progressive inability to walk (HP:0002505)1.85712217
140Bradycardia (HP:0001662)1.85412925
141Pachygyria (HP:0001302)1.84777091
142Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.84252188
143Postaxial foot polydactyly (HP:0001830)1.83788800
144Facial cleft (HP:0002006)1.83538397
145Esotropia (HP:0000565)1.82612296
146Anterior segment dysgenesis (HP:0007700)1.82414543
147Abnormality of the line of Schwalbe (HP:0008048)1.82164288
148Conjunctival hamartoma (HP:0100780)1.81611174
149Concave nail (HP:0001598)1.81106367
150Restlessness (HP:0000711)1.80890254
151Optic disc pallor (HP:0000543)1.80552056
152Impaired vibration sensation in the lower limbs (HP:0002166)1.80085121
153Abnormal number of erythroid precursors (HP:0012131)1.79780355
154Hypogonadotrophic hypogonadism (HP:0000044)1.79366958
155Narrow forehead (HP:0000341)1.78811681
156Nasal polyposis (HP:0100582)1.75963448
157Abnormality of the labia (HP:0000058)1.75866906
158Myotonia (HP:0002486)1.75426499
159Absent eyelashes (HP:0000561)1.75374256
160Atrioventricular canal defect (HP:0006695)1.74928390
161Urinary bladder sphincter dysfunction (HP:0002839)1.74413853
162Exotropia (HP:0000577)1.74156967
163Infertility (HP:0000789)1.73750244
164Left ventricular hypertrophy (HP:0001712)1.72202856
165Prominent nasal bridge (HP:0000426)1.71829905
166Hyperventilation (HP:0002883)1.71735671
167Neuroendocrine neoplasm (HP:0100634)1.71275500
168Polymicrogyria (HP:0002126)1.68868406
169Tubulointerstitial abnormality (HP:0001969)1.65754176
170Hemiparesis (HP:0001269)1.65491697
171Morphological abnormality of the pyramidal tract (HP:0002062)1.65308404
172Specific learning disability (HP:0001328)1.65239624
173Anencephaly (HP:0002323)1.64875178
174Recurrent sinusitis (HP:0011108)1.64321922
175Pulmonary artery stenosis (HP:0004415)1.61726845

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PHKG15.86695491
2PHKG25.86695491
3ARAF4.61587619
4MAPK153.19329241
5ERBB33.07989763
6INSRR3.07156500
7MAPKAPK33.01915960
8DYRK22.98989067
9PAK32.96273622
10EEF2K2.87028920
11EPHA42.74965091
12PIM22.46725177
13DAPK22.42169192
14WNK32.29613173
15TNIK2.27762329
16CDK192.24901499
17STK242.15411708
18NUAK12.12048441
19CAMK2D2.09750244
20CAMK2B2.05640313
21CDC71.99079890
22CAMK2G1.72412813
23STK38L1.72122255
24ICK1.59459405
25BRAF1.58497348
26ILK1.58367900
27CSNK1A1L1.57922253
28EPHB11.54335862
29CAMKK21.47258957
30RIPK11.45655267
31WNK41.35070483
32DAPK11.30574675
33PNCK1.29250162
34CSNK1G31.26856563
35MAP3K91.26245869
36MAP2K71.24673550
37CAMK1D1.24409898
38PASK1.22678075
39RPS6KA21.21193635
40CAMK1G1.20602933
41PINK11.20409747
42PRPF4B1.18698691
43MAPK131.16800280
44MAP3K21.16518248
45NTRK31.13867047
46STK161.11931698
47CSNK1G21.08274078
48CSNK1G11.02127161
49MAP3K41.01909470
50TRIM281.01016561
51PRKCG0.99453059
52ZAK0.99025162
53PLK30.95821894
54MAP3K30.90136944
55TRIB30.88896831
56HIPK20.88501493
57TYRO30.88253454
58ALK0.87500598
59MARK10.85320683
60MAP3K60.82363559
61TRPM70.81685433
62DYRK1B0.80496891
63GRK50.79366835
64VRK10.79315637
65TSSK60.79094761
66CDK140.78973186
67ADRBK20.78078692
68BCR0.77918741
69FRK0.77812423
70DYRK30.77018474
71PLK10.76810752
72MINK10.71881093
73CSNK1E0.71796848
74GRK10.71100001
75NLK0.70749762
76SIK20.70442034
77OXSR10.69458749
78GRK60.68753038
79MAP3K100.67842391
80CDK11A0.67128528
81BRSK10.66347578
82PRKD30.66115866
83PAK60.65348920
84CDK30.64493780
85MAPKAPK50.62463524
86CDK150.62330639
87CAMKK10.61980421
88STK380.61745238
89CHEK10.61491057
90STK390.61130745
91AKT30.60985527
92MAP4K20.60386157
93NTRK20.60385620
94CDK180.60141547
95DYRK1A0.59329409
96CASK0.57304670
97NEK60.57205781
98CAMK2A0.56527382
99MAPKAPK20.55732393
100SRPK10.55302336
101IRAK10.53518477
102PLK20.49117868
103UHMK10.48746778
104DDR20.47983468
105PIK3CA0.47893443
106MAP2K40.46180939
107PRKACB0.45944654
108TIE10.45578776
109CHEK20.45342851
110RAF10.44432145
111DAPK30.42884400
112MAP2K20.42781976
113STK110.42711480
114MAPK90.42661600
115VRK20.42275655
116CSNK1D0.42165009
117CDK20.41828204
118EPHB20.40668376
119ATM0.40439141
120PRKCA0.40131068
121CDK50.39966223
122TAOK30.39595041
123TTK0.39140567
124MST40.39024277
125MAPK110.38637040
126MAP3K50.38189509
127SGK2230.37335823
128SGK4940.37335823
129CSNK1A10.36960299
130CAMK40.36227377
131PRKAA20.35879899
132MAP3K70.35263216
133NTRK10.34690912
134DMPK0.34238900
135PRKCI0.30956257
136TXK0.30050519
137PRKCQ0.28474595
138PRKCZ0.28419245
139FER0.26297650
140PKN10.25174108
141PRKCE0.24864988
142PRKD10.24427737
143AKT20.23255546
144MAPK70.22806845
145AURKA0.22123606
146PRKG20.22011882
147FYN0.20813750
148ROCK20.20512771
149PRKACG0.19903486
150SGK20.19319390
151PRKACA0.19252306
152RPS6KA60.18779226
153FGR0.18538731
154PRKG10.18083328
155MARK30.17776713
156PRKAA10.17498719
157RPS6KC10.17208822

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.05483805
2Phototransduction_Homo sapiens_hsa047442.97909599
3Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.80429973
4Basal transcription factors_Homo sapiens_hsa030222.30806405
5Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.21576408
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03028796
7Olfactory transduction_Homo sapiens_hsa0474012.3454579
8Circadian entrainment_Homo sapiens_hsa047131.91778034
9Taste transduction_Homo sapiens_hsa047421.89605054
10Morphine addiction_Homo sapiens_hsa050321.80699217
11Dopaminergic synapse_Homo sapiens_hsa047281.67947033
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.63089061
13Steroid biosynthesis_Homo sapiens_hsa001001.58087201
14Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.56147847
15Insulin secretion_Homo sapiens_hsa049111.53932022
16RNA polymerase_Homo sapiens_hsa030201.52912657
17GABAergic synapse_Homo sapiens_hsa047271.47143772
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.46781389
19Butanoate metabolism_Homo sapiens_hsa006501.46199971
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.39086355
21Cholinergic synapse_Homo sapiens_hsa047251.39035444
22Sulfur relay system_Homo sapiens_hsa041221.38696939
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.38184908
24Glutamatergic synapse_Homo sapiens_hsa047241.33895339
25Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.32484825
26cAMP signaling pathway_Homo sapiens_hsa040241.32256142
27Histidine metabolism_Homo sapiens_hsa003401.31096289
28Fatty acid biosynthesis_Homo sapiens_hsa000611.24195300
29Alcoholism_Homo sapiens_hsa050341.23437181
30Folate biosynthesis_Homo sapiens_hsa007901.23160970
31Gastric acid secretion_Homo sapiens_hsa049711.20302984
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.17249477
33Fanconi anemia pathway_Homo sapiens_hsa034601.14858831
34Vibrio cholerae infection_Homo sapiens_hsa051101.12057808
35Ovarian steroidogenesis_Homo sapiens_hsa049131.11602081
36RNA degradation_Homo sapiens_hsa030181.09954860
37Salivary secretion_Homo sapiens_hsa049701.08950572
38cGMP-PKG signaling pathway_Homo sapiens_hsa040221.07594906
39Parkinsons disease_Homo sapiens_hsa050121.07288073
40Synaptic vesicle cycle_Homo sapiens_hsa047211.06820252
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.06674578
42beta-Alanine metabolism_Homo sapiens_hsa004100.98368813
43Ribosome_Homo sapiens_hsa030100.97293773
44Bile secretion_Homo sapiens_hsa049760.97214759
45Ether lipid metabolism_Homo sapiens_hsa005650.91351965
46Thyroid hormone synthesis_Homo sapiens_hsa049180.90182704
47Amphetamine addiction_Homo sapiens_hsa050310.88976341
48Glucagon signaling pathway_Homo sapiens_hsa049220.84615279
49GnRH signaling pathway_Homo sapiens_hsa049120.83494605
50Calcium signaling pathway_Homo sapiens_hsa040200.83388084
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82975178
52Cell cycle_Homo sapiens_hsa041100.81595683
53Serotonergic synapse_Homo sapiens_hsa047260.80230379
54Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.79926509
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79543557
56Homologous recombination_Homo sapiens_hsa034400.79527633
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.79477050
58Alzheimers disease_Homo sapiens_hsa050100.78256532
59Proteasome_Homo sapiens_hsa030500.76982620
60Estrogen signaling pathway_Homo sapiens_hsa049150.75729379
61Sphingolipid metabolism_Homo sapiens_hsa006000.74389686
62DNA replication_Homo sapiens_hsa030300.72025715
63Base excision repair_Homo sapiens_hsa034100.71138960
64ABC transporters_Homo sapiens_hsa020100.70556102
65Long-term potentiation_Homo sapiens_hsa047200.68286478
66RNA transport_Homo sapiens_hsa030130.68004546
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67219478
68Oxidative phosphorylation_Homo sapiens_hsa001900.64197226
69Renin secretion_Homo sapiens_hsa049240.63982823
70Linoleic acid metabolism_Homo sapiens_hsa005910.63749524
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.63438409
72Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62955868
73Melanogenesis_Homo sapiens_hsa049160.62953931
74Caffeine metabolism_Homo sapiens_hsa002320.62868700
75Collecting duct acid secretion_Homo sapiens_hsa049660.62844948
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62115905
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.59244676
78Long-term depression_Homo sapiens_hsa047300.59008798
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56108036
80Basal cell carcinoma_Homo sapiens_hsa052170.55941886
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55623746
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55251025
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54991551
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54696066
85Maturity onset diabetes of the young_Homo sapiens_hsa049500.54267547
86Hedgehog signaling pathway_Homo sapiens_hsa043400.53597055
87Insulin signaling pathway_Homo sapiens_hsa049100.53394847
88Metabolic pathways_Homo sapiens_hsa011000.53066827
89Selenocompound metabolism_Homo sapiens_hsa004500.52880615
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51923322
91Drug metabolism - other enzymes_Homo sapiens_hsa009830.51580861
92Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51007436
93Systemic lupus erythematosus_Homo sapiens_hsa053220.50604492
94Mismatch repair_Homo sapiens_hsa034300.50427442
95Gap junction_Homo sapiens_hsa045400.50384143
96alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49634451
97Oxytocin signaling pathway_Homo sapiens_hsa049210.48861272
98Pyruvate metabolism_Homo sapiens_hsa006200.47798891
99Huntingtons disease_Homo sapiens_hsa050160.46866201
100Ras signaling pathway_Homo sapiens_hsa040140.46760306
101Pyrimidine metabolism_Homo sapiens_hsa002400.45522166
102Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44833349
103Purine metabolism_Homo sapiens_hsa002300.44725883
104Nitrogen metabolism_Homo sapiens_hsa009100.44570557
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.44525448
106Cardiac muscle contraction_Homo sapiens_hsa042600.44381217
107Mineral absorption_Homo sapiens_hsa049780.42681939
108Sulfur metabolism_Homo sapiens_hsa009200.42003260
109mRNA surveillance pathway_Homo sapiens_hsa030150.41789930
110Hippo signaling pathway_Homo sapiens_hsa043900.40996379
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39069980
112N-Glycan biosynthesis_Homo sapiens_hsa005100.38323733
113Oocyte meiosis_Homo sapiens_hsa041140.37294603
114Pancreatic secretion_Homo sapiens_hsa049720.36840816
115Spliceosome_Homo sapiens_hsa030400.36459362
116Retinol metabolism_Homo sapiens_hsa008300.35961911
117Type II diabetes mellitus_Homo sapiens_hsa049300.35888955
118Vitamin digestion and absorption_Homo sapiens_hsa049770.35887919
119Fat digestion and absorption_Homo sapiens_hsa049750.35206748
120Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.35123405
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.34913283
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.34392442
123Chemical carcinogenesis_Homo sapiens_hsa052040.34101816
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32612877
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.32187863
126Chemokine signaling pathway_Homo sapiens_hsa040620.31645871
127Cocaine addiction_Homo sapiens_hsa050300.31351272
128Arachidonic acid metabolism_Homo sapiens_hsa005900.28302839
129Dilated cardiomyopathy_Homo sapiens_hsa054140.28258680
130Rap1 signaling pathway_Homo sapiens_hsa040150.27818502
131Axon guidance_Homo sapiens_hsa043600.27000876
132Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.25940887
133Fatty acid degradation_Homo sapiens_hsa000710.25434007
134Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.24618691
135Other glycan degradation_Homo sapiens_hsa005110.24416684
136Arginine and proline metabolism_Homo sapiens_hsa003300.22539667
137Phosphatidylinositol signaling system_Homo sapiens_hsa040700.22295692
138Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.22290421
139Adipocytokine signaling pathway_Homo sapiens_hsa049200.22216417
140Hepatitis C_Homo sapiens_hsa051600.21500961
141Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.21419054
142Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.21088431
143Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.20875377
144Glioma_Homo sapiens_hsa052140.20241330
145Propanoate metabolism_Homo sapiens_hsa006400.20212648
146Pancreatic cancer_Homo sapiens_hsa052120.19621636
147Peroxisome_Homo sapiens_hsa041460.18641588
148Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.17912242
149Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.17842992
150Colorectal cancer_Homo sapiens_hsa052100.16970883
151Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16620275
152Prion diseases_Homo sapiens_hsa050200.15164709
153Amoebiasis_Homo sapiens_hsa051460.14506005
154Steroid hormone biosynthesis_Homo sapiens_hsa001400.11605995
155Notch signaling pathway_Homo sapiens_hsa043300.11068372

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »