

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | acrosome reaction (GO:0007340) | 8.95742506 |
| 2 | sperm motility (GO:0030317) | 8.21637451 |
| 3 | response to pheromone (GO:0019236) | 8.05685513 |
| 4 | fusion of sperm to egg plasma membrane (GO:0007342) | 7.87047435 |
| 5 | sperm capacitation (GO:0048240) | 7.64935478 |
| 6 | chromosome condensation (GO:0030261) | 6.45646296 |
| 7 | negative regulation of inclusion body assembly (GO:0090084) | 6.31084690 |
| 8 | DNA packaging (GO:0006323) | 6.12056373 |
| 9 | plasma membrane fusion (GO:0045026) | 6.08547653 |
| 10 | calcium ion-dependent exocytosis (GO:0017156) | 6.04874942 |
| 11 | spermatid nucleus differentiation (GO:0007289) | 5.85941680 |
| 12 | single strand break repair (GO:0000012) | 5.65333032 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.50012256 |
| 14 | microtubule depolymerization (GO:0007019) | 5.42355240 |
| 15 | spermatid development (GO:0007286) | 5.31102416 |
| 16 | sexual reproduction (GO:0019953) | 5.29405820 |
| 17 | microtubule polymerization or depolymerization (GO:0031109) | 4.95893796 |
| 18 | sperm-egg recognition (GO:0035036) | 4.95309076 |
| 19 | multicellular organism reproduction (GO:0032504) | 4.88732327 |
| 20 | reproduction (GO:0000003) | 4.81594172 |
| 21 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.68605615 |
| 22 | regulation of inclusion body assembly (GO:0090083) | 4.66699891 |
| 23 | synaptic vesicle maturation (GO:0016188) | 4.66435338 |
| 24 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.59588495 |
| 25 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.46805721 |
| 26 | binding of sperm to zona pellucida (GO:0007339) | 4.38176364 |
| 27 | locomotory exploration behavior (GO:0035641) | 4.36827650 |
| 28 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 4.30959535 |
| 29 | glutamate secretion (GO:0014047) | 4.19456159 |
| 30 | synaptic vesicle exocytosis (GO:0016079) | 4.16767281 |
| 31 | postsynaptic membrane organization (GO:0001941) | 4.15857244 |
| 32 | cell-cell recognition (GO:0009988) | 4.13083385 |
| 33 | positive regulation of Rab GTPase activity (GO:0032851) | 4.11041173 |
| 34 | regulation of Rab GTPase activity (GO:0032313) | 4.11041173 |
| 35 | sodium ion export (GO:0071436) | 4.06863530 |
| 36 | spermatogenesis (GO:0007283) | 3.99278903 |
| 37 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.99018911 |
| 38 | phosphatidylethanolamine metabolic process (GO:0046337) | 3.98666168 |
| 39 | male gamete generation (GO:0048232) | 3.97360508 |
| 40 | protein polyglutamylation (GO:0018095) | 3.96313993 |
| 41 | cellular ketone body metabolic process (GO:0046950) | 3.94529470 |
| 42 | protein targeting to Golgi (GO:0000042) | 3.91300058 |
| 43 | regulation of synaptic vesicle transport (GO:1902803) | 3.87070518 |
| 44 | chromatin silencing (GO:0006342) | 3.85187015 |
| 45 | establishment of protein localization to Golgi (GO:0072600) | 3.71328609 |
| 46 | cerebral cortex neuron differentiation (GO:0021895) | 3.69205895 |
| 47 | microtubule severing (GO:0051013) | 3.68945625 |
| 48 | axonemal dynein complex assembly (GO:0070286) | 3.68021488 |
| 49 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.66891469 |
| 50 | gamete generation (GO:0007276) | 3.60584182 |
| 51 | rRNA methylation (GO:0031167) | 3.59763143 |
| 52 | neuronal ion channel clustering (GO:0045161) | 3.59599522 |
| 53 | response to acidic pH (GO:0010447) | 3.56563424 |
| 54 | exploration behavior (GO:0035640) | 3.55923267 |
| 55 | regulation of transcription involved in cell fate commitment (GO:0060850) | 3.53937757 |
| 56 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.51567767 |
| 57 | positive regulation of membrane potential (GO:0045838) | 3.45680958 |
| 58 | ketone body metabolic process (GO:1902224) | 3.43351869 |
| 59 | negative regulation of Rho protein signal transduction (GO:0035024) | 3.42007328 |
| 60 | L-amino acid import (GO:0043092) | 3.30802786 |
| 61 | regulation of ARF GTPase activity (GO:0032312) | 3.30132236 |
| 62 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.29475529 |
| 63 | regulation of ARF protein signal transduction (GO:0032012) | 3.22820793 |
| 64 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.22673710 |
| 65 | neuron cell-cell adhesion (GO:0007158) | 3.22045446 |
| 66 | protein localization to synapse (GO:0035418) | 3.19408026 |
| 67 | coenzyme catabolic process (GO:0009109) | 3.18994171 |
| 68 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.16856552 |
| 69 | regulation of microtubule-based movement (GO:0060632) | 3.15956551 |
| 70 | membrane depolarization during action potential (GO:0086010) | 3.08746999 |
| 71 | neurotransmitter secretion (GO:0007269) | 3.08483464 |
| 72 | motile cilium assembly (GO:0044458) | 3.08358887 |
| 73 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.07838987 |
| 74 | cellular potassium ion homeostasis (GO:0030007) | 3.07586861 |
| 75 | RNA destabilization (GO:0050779) | 3.07127079 |
| 76 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.05821562 |
| 77 | regulation of cilium movement (GO:0003352) | 3.05801460 |
| 78 | regulation of interleukin-13 production (GO:0032656) | 3.04005352 |
| 79 | regulation of somitogenesis (GO:0014807) | 3.03989887 |
| 80 | single fertilization (GO:0007338) | 3.02304811 |
| 81 | synaptic transmission, glutamatergic (GO:0035249) | 3.00636846 |
| 82 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.98783306 |
| 83 | cellular response to pH (GO:0071467) | 2.93802363 |
| 84 | germ cell development (GO:0007281) | 2.92641424 |
| 85 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 2.92563903 |
| 86 | actin filament capping (GO:0051693) | 2.92526218 |
| 87 | neuromuscular synaptic transmission (GO:0007274) | 2.92329282 |
| 88 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.89080932 |
| 89 | multicellular organismal reproductive process (GO:0048609) | 2.88845288 |
| 90 | dendritic spine organization (GO:0097061) | 2.87946724 |
| 91 | long-term memory (GO:0007616) | 2.87018240 |
| 92 | vocalization behavior (GO:0071625) | 2.86832620 |
| 93 | urinary tract smooth muscle contraction (GO:0014848) | 2.85847625 |
| 94 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.85222073 |
| 95 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.84722279 |
| 96 | amino acid import (GO:0043090) | 2.79615363 |
| 97 | rRNA modification (GO:0000154) | 2.76774537 |
| 98 | vesicle transport along microtubule (GO:0047496) | 2.75449007 |
| 99 | cell wall macromolecule catabolic process (GO:0016998) | 2.74744034 |
| 100 | cranial nerve morphogenesis (GO:0021602) | 2.73118118 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 3.93524875 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.75934479 |
| 3 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.97433394 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.95128879 |
| 5 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.53199303 |
| 6 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.52006758 |
| 7 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.29771936 |
| 8 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.17903573 |
| 9 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.09216726 |
| 10 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.06567838 |
| 11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.01981788 |
| 12 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.00965624 |
| 13 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.94504656 |
| 14 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.94148869 |
| 15 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.91167273 |
| 16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.87018371 |
| 17 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.85540886 |
| 18 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.84638971 |
| 19 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.83984703 |
| 20 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.83211594 |
| 21 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.82233345 |
| 22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.81671551 |
| 23 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.79553105 |
| 24 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.79553105 |
| 25 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.79300490 |
| 26 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.76629600 |
| 27 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.67062908 |
| 28 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.61491462 |
| 29 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.59386638 |
| 30 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.59386638 |
| 31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.55548838 |
| 32 | P68_20966046_ChIP-Seq_HELA_Human | 1.55189908 |
| 33 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.53036710 |
| 34 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.46150168 |
| 35 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.40422806 |
| 36 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.38200900 |
| 37 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.37184236 |
| 38 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.37056229 |
| 39 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.36327892 |
| 40 | ERA_21632823_ChIP-Seq_H3396_Human | 1.35106369 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.34851750 |
| 42 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.34791893 |
| 43 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.33201459 |
| 44 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.31276814 |
| 45 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.30911698 |
| 46 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.30797558 |
| 47 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.29968618 |
| 48 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29714249 |
| 49 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.29281624 |
| 50 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.29106450 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28729673 |
| 52 | KDM2B_26808549_Chip-Seq_K562_Human | 1.27656760 |
| 53 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.27191203 |
| 54 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.23946890 |
| 55 | SA1_27219007_Chip-Seq_Bcells_Human | 1.21838553 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.21668795 |
| 57 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.20804719 |
| 58 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.20789934 |
| 59 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.19416194 |
| 60 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.18812598 |
| 61 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.16690235 |
| 62 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.16294964 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.16046484 |
| 64 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.15653349 |
| 65 | KLF4_19829295_ChIP-Seq_ESCs_Human | 1.14676907 |
| 66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14201479 |
| 67 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14201479 |
| 68 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.14071325 |
| 69 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.10655454 |
| 70 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.10619261 |
| 71 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09712277 |
| 72 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.09398353 |
| 73 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.08903168 |
| 74 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.07798597 |
| 75 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.07349092 |
| 76 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.05293258 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.04402696 |
| 78 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.04325851 |
| 79 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.04250853 |
| 80 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.03030828 |
| 81 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.02677515 |
| 82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.00307345 |
| 83 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.99833632 |
| 84 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.98639774 |
| 85 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.96885329 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.96220471 |
| 87 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.96066432 |
| 88 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.95217195 |
| 89 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.94235755 |
| 90 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.92887483 |
| 91 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92392778 |
| 92 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.91885292 |
| 93 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91433710 |
| 94 | P300_27268052_Chip-Seq_Bcells_Human | 0.90678371 |
| 95 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.90501546 |
| 96 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 0.90468061 |
| 97 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.88484566 |
| 98 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.88349636 |
| 99 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.88238030 |
| 100 | AR_25329375_ChIP-Seq_VCAP_Human | 0.87910410 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005410_abnormal_fertilization | 7.50717691 |
| 2 | MP0004859_abnormal_synaptic_plasticity | 5.44227578 |
| 3 | MP0005423_abnormal_somatic_nervous | 3.78286563 |
| 4 | MP0003880_abnormal_central_pattern | 3.45946834 |
| 5 | MP0003635_abnormal_synaptic_transmissio | 3.11264518 |
| 6 | MP0004270_analgesia | 2.85972548 |
| 7 | MP0001486_abnormal_startle_reflex | 2.77629310 |
| 8 | MP0005670_abnormal_white_adipose | 2.76791147 |
| 9 | MP0003698_abnormal_male_reproductive | 2.72671708 |
| 10 | MP0003878_abnormal_ear_physiology | 2.70225941 |
| 11 | MP0005377_hearing/vestibular/ear_phenot | 2.70225941 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.67920043 |
| 13 | MP0001348_abnormal_lacrimal_gland | 2.61537066 |
| 14 | MP0002064_seizures | 2.57046418 |
| 15 | MP0009745_abnormal_behavioral_response | 2.50143583 |
| 16 | MP0002063_abnormal_learning/memory/cond | 2.34223479 |
| 17 | MP0002735_abnormal_chemical_nociception | 2.23037300 |
| 18 | MP0002734_abnormal_mechanical_nocicepti | 2.22393090 |
| 19 | MP0002272_abnormal_nervous_system | 2.21514559 |
| 20 | MP0002572_abnormal_emotion/affect_behav | 2.17092190 |
| 21 | MP0001929_abnormal_gametogenesis | 2.08124803 |
| 22 | MP0003879_abnormal_hair_cell | 1.98559282 |
| 23 | MP0008569_lethality_at_weaning | 1.91984226 |
| 24 | MP0002733_abnormal_thermal_nociception | 1.89783258 |
| 25 | MP0004510_myositis | 1.88167797 |
| 26 | MP0001501_abnormal_sleep_pattern | 1.87255289 |
| 27 | MP0001970_abnormal_pain_threshold | 1.79216977 |
| 28 | MP0003329_amyloid_beta_deposits | 1.79007687 |
| 29 | MP0002822_catalepsy | 1.69206224 |
| 30 | MP0000678_abnormal_parathyroid_gland | 1.64331305 |
| 31 | MP0004742_abnormal_vestibular_system | 1.61053676 |
| 32 | MP0009046_muscle_twitch | 1.56947822 |
| 33 | MP0004885_abnormal_endolymph | 1.55818395 |
| 34 | MP0002161_abnormal_fertility/fecundity | 1.53554830 |
| 35 | MP0002067_abnormal_sensory_capabilities | 1.51402145 |
| 36 | MP0002736_abnormal_nociception_after | 1.48923678 |
| 37 | MP0001485_abnormal_pinna_reflex | 1.44791099 |
| 38 | MP0002557_abnormal_social/conspecific_i | 1.43649278 |
| 39 | MP0001502_abnormal_circadian_rhythm | 1.43434191 |
| 40 | MP0003690_abnormal_glial_cell | 1.42184685 |
| 41 | MP0000955_abnormal_spinal_cord | 1.41749941 |
| 42 | MP0003011_delayed_dark_adaptation | 1.36794987 |
| 43 | MP0002249_abnormal_larynx_morphology | 1.30924387 |
| 44 | MP0001440_abnormal_grooming_behavior | 1.28558609 |
| 45 | MP0001905_abnormal_dopamine_level | 1.26833449 |
| 46 | MP0004811_abnormal_neuron_physiology | 1.26643261 |
| 47 | MP0001984_abnormal_olfaction | 1.25634191 |
| 48 | MP0001963_abnormal_hearing_physiology | 1.24831756 |
| 49 | MP0003633_abnormal_nervous_system | 1.24109477 |
| 50 | MP0000920_abnormal_myelination | 1.19698937 |
| 51 | MP0002132_abnormal_respiratory_system | 1.15752811 |
| 52 | MP0002229_neurodegeneration | 1.14965637 |
| 53 | MP0002882_abnormal_neuron_morphology | 1.13595581 |
| 54 | MP0003787_abnormal_imprinting | 1.11651997 |
| 55 | MP0005167_abnormal_blood-brain_barrier | 1.10014870 |
| 56 | MP0003631_nervous_system_phenotype | 1.09484282 |
| 57 | MP0002638_abnormal_pupillary_reflex | 1.08656554 |
| 58 | MP0005646_abnormal_pituitary_gland | 1.07325561 |
| 59 | MP0003172_abnormal_lysosome_physiology | 1.06419855 |
| 60 | MP0006276_abnormal_autonomic_nervous | 1.04716243 |
| 61 | MP0001765_abnormal_ion_homeostasis | 1.00349166 |
| 62 | MP0008877_abnormal_DNA_methylation | 0.95951966 |
| 63 | MP0000778_abnormal_nervous_system | 0.95643817 |
| 64 | MP0000026_abnormal_inner_ear | 0.95384174 |
| 65 | MP0002066_abnormal_motor_capabilities/c | 0.94194206 |
| 66 | MP0005535_abnormal_body_temperature | 0.93401502 |
| 67 | MP0005379_endocrine/exocrine_gland_phen | 0.93217745 |
| 68 | MP0009780_abnormal_chondrocyte_physiolo | 0.92304479 |
| 69 | MP0002234_abnormal_pharynx_morphology | 0.92209938 |
| 70 | MP0002653_abnormal_ependyma_morphology | 0.91460332 |
| 71 | MP0008874_decreased_physiological_sensi | 0.91120815 |
| 72 | MP0005310_abnormal_salivary_gland | 0.89282689 |
| 73 | MP0003646_muscle_fatigue | 0.86853454 |
| 74 | MP0000604_amyloidosis | 0.85095340 |
| 75 | MP0000681_abnormal_thyroid_gland | 0.84382547 |
| 76 | MP0005166_decreased_susceptibility_to | 0.84211042 |
| 77 | MP0005551_abnormal_eye_electrophysiolog | 0.83230110 |
| 78 | MP0003632_abnormal_nervous_system | 0.75331080 |
| 79 | MP0003634_abnormal_glial_cell | 0.74429815 |
| 80 | MP0002152_abnormal_brain_morphology | 0.73957132 |
| 81 | MP0002210_abnormal_sex_determination | 0.69407514 |
| 82 | MP0004142_abnormal_muscle_tone | 0.68787519 |
| 83 | MP0005386_behavior/neurological_phenoty | 0.67607115 |
| 84 | MP0004924_abnormal_behavior | 0.67607115 |
| 85 | MP0000534_abnormal_ureter_morphology | 0.66001837 |
| 86 | MP0005645_abnormal_hypothalamus_physiol | 0.61452684 |
| 87 | MP0003075_altered_response_to | 0.60778421 |
| 88 | MP0002184_abnormal_innervation | 0.60662044 |
| 89 | MP0003183_abnormal_peptide_metabolism | 0.60075465 |
| 90 | MP0004085_abnormal_heartbeat | 0.59131869 |
| 91 | MP0002069_abnormal_eating/drinking_beha | 0.57520222 |
| 92 | MP0004130_abnormal_muscle_cell | 0.55931617 |
| 93 | MP0002282_abnormal_trachea_morphology | 0.55524806 |
| 94 | MP0001986_abnormal_taste_sensitivity | 0.53918701 |
| 95 | MP0004484_altered_response_of | 0.53383227 |
| 96 | MP0001145_abnormal_male_reproductive | 0.53057154 |
| 97 | MP0000653_abnormal_sex_gland | 0.49943483 |
| 98 | MP0003137_abnormal_impulse_conducting | 0.49419734 |
| 99 | MP0002752_abnormal_somatic_nervous | 0.48722134 |
| 100 | MP0001177_atelectasis | 0.47926757 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 6.24417686 |
| 2 | Severe visual impairment (HP:0001141) | 6.17284213 |
| 3 | Resting tremor (HP:0002322) | 4.22799345 |
| 4 | Postural instability (HP:0002172) | 4.21717454 |
| 5 | Focal motor seizures (HP:0011153) | 4.14528064 |
| 6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.94609446 |
| 7 | Absent/shortened dynein arms (HP:0200106) | 3.94609446 |
| 8 | Attenuation of retinal blood vessels (HP:0007843) | 3.79588287 |
| 9 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.74726122 |
| 10 | Peripheral hypomyelination (HP:0007182) | 3.69291161 |
| 11 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.67886869 |
| 12 | Action tremor (HP:0002345) | 3.67526289 |
| 13 | Progressive cerebellar ataxia (HP:0002073) | 3.64944734 |
| 14 | Asymmetric septal hypertrophy (HP:0001670) | 3.50104921 |
| 15 | Atonic seizures (HP:0010819) | 3.45792569 |
| 16 | Focal seizures (HP:0007359) | 3.41592844 |
| 17 | Diplopia (HP:0000651) | 3.38722437 |
| 18 | Abnormality of binocular vision (HP:0011514) | 3.38722437 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.36848785 |
| 20 | Bell-shaped thorax (HP:0001591) | 3.35878077 |
| 21 | Epileptic encephalopathy (HP:0200134) | 3.23405277 |
| 22 | Hypoplastic ischia (HP:0003175) | 3.21356726 |
| 23 | Enlarged epiphyses (HP:0010580) | 3.10631269 |
| 24 | Facial shape deformation (HP:0011334) | 3.05509493 |
| 25 | Potter facies (HP:0002009) | 3.05509493 |
| 26 | Febrile seizures (HP:0002373) | 3.02908114 |
| 27 | Hyperkalemia (HP:0002153) | 3.02278913 |
| 28 | Abnormality of the ischium (HP:0003174) | 2.99512771 |
| 29 | Nasal polyposis (HP:0100582) | 2.97280657 |
| 30 | Abnormal ciliary motility (HP:0012262) | 2.95296883 |
| 31 | Unilateral renal agenesis (HP:0000122) | 2.86125166 |
| 32 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.86010981 |
| 33 | Infertility (HP:0000789) | 2.80935236 |
| 34 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.74733825 |
| 35 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.74733825 |
| 36 | Bowel incontinence (HP:0002607) | 2.74275653 |
| 37 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.74082170 |
| 38 | Papilledema (HP:0001085) | 2.72576420 |
| 39 | Amblyopia (HP:0000646) | 2.69212064 |
| 40 | Congenital malformation of the right heart (HP:0011723) | 2.67784343 |
| 41 | Double outlet right ventricle (HP:0001719) | 2.67784343 |
| 42 | Supranuclear gaze palsy (HP:0000605) | 2.67740847 |
| 43 | Delusions (HP:0000746) | 2.63234757 |
| 44 | Abnormality of macular pigmentation (HP:0008002) | 2.62515372 |
| 45 | Cerebral inclusion bodies (HP:0100314) | 2.62127045 |
| 46 | Stereotypic behavior (HP:0000733) | 2.61973565 |
| 47 | Ankle clonus (HP:0011448) | 2.60366536 |
| 48 | Bradykinesia (HP:0002067) | 2.58592966 |
| 49 | Abnormality of the aortic arch (HP:0012303) | 2.57218265 |
| 50 | Male infertility (HP:0003251) | 2.56519920 |
| 51 | Hypoplasia of the thymus (HP:0000778) | 2.53615353 |
| 52 | Neurofibrillary tangles (HP:0002185) | 2.53597991 |
| 53 | Abnormal large intestine physiology (HP:0012700) | 2.50819134 |
| 54 | Dysmetria (HP:0001310) | 2.50793996 |
| 55 | Hyperthyroidism (HP:0000836) | 2.50171713 |
| 56 | Intention tremor (HP:0002080) | 2.45050199 |
| 57 | Visual hallucinations (HP:0002367) | 2.44979879 |
| 58 | Hemiplegia (HP:0002301) | 2.44902383 |
| 59 | Obstructive sleep apnea (HP:0002870) | 2.42569763 |
| 60 | Abnormal eating behavior (HP:0100738) | 2.40697568 |
| 61 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 2.33997621 |
| 62 | Abnormality of the nasal mucosa (HP:0000433) | 2.30734759 |
| 63 | Slow saccadic eye movements (HP:0000514) | 2.25554790 |
| 64 | Azoospermia (HP:0000027) | 2.24569347 |
| 65 | Truncus arteriosus (HP:0001660) | 2.20394443 |
| 66 | Mutism (HP:0002300) | 2.19965198 |
| 67 | Absence seizures (HP:0002121) | 2.18357317 |
| 68 | Abnormal urine output (HP:0012590) | 2.16604361 |
| 69 | Impulsivity (HP:0100710) | 2.13208005 |
| 70 | Neoplasm of the heart (HP:0100544) | 2.10387452 |
| 71 | Spastic gait (HP:0002064) | 2.07944670 |
| 72 | Rigidity (HP:0002063) | 2.07018482 |
| 73 | Increased circulating renin level (HP:0000848) | 2.06565338 |
| 74 | Depression (HP:0000716) | 2.03572116 |
| 75 | Dialeptic seizures (HP:0011146) | 2.02368604 |
| 76 | Abnormal drinking behavior (HP:0030082) | 2.01449595 |
| 77 | Polydipsia (HP:0001959) | 2.01449595 |
| 78 | Abnormality of potassium homeostasis (HP:0011042) | 1.99770072 |
| 79 | Progressive sensorineural hearing impairment (HP:0000408) | 1.99561412 |
| 80 | Akinesia (HP:0002304) | 1.94915341 |
| 81 | Cerebral hypomyelination (HP:0006808) | 1.92216909 |
| 82 | Renal dysplasia (HP:0000110) | 1.90760901 |
| 83 | Abnormal spermatogenesis (HP:0008669) | 1.90218518 |
| 84 | Chronic hepatic failure (HP:0100626) | 1.89284006 |
| 85 | Torticollis (HP:0000473) | 1.88976932 |
| 86 | Epiphyseal dysplasia (HP:0002656) | 1.83360664 |
| 87 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.83169479 |
| 88 | Dysdiadochokinesis (HP:0002075) | 1.82992881 |
| 89 | Sensory axonal neuropathy (HP:0003390) | 1.82542435 |
| 90 | Tetraplegia (HP:0002445) | 1.81501244 |
| 91 | Truncal obesity (HP:0001956) | 1.80382327 |
| 92 | Abnormality of saccadic eye movements (HP:0000570) | 1.78254928 |
| 93 | Limb dystonia (HP:0002451) | 1.77072260 |
| 94 | Abnormality of renal excretion (HP:0011036) | 1.74156159 |
| 95 | Polyuria (HP:0000103) | 1.71689476 |
| 96 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.71276842 |
| 97 | Tubulointerstitial nephritis (HP:0001970) | 1.69381517 |
| 98 | Rapidly progressive (HP:0003678) | 1.68326259 |
| 99 | Mixed hearing impairment (HP:0000410) | 1.67663502 |
| 100 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.67429463 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK1 | 4.83285305 |
| 2 | PLK4 | 4.03765729 |
| 3 | DDR2 | 3.63612328 |
| 4 | PRKD3 | 3.28393156 |
| 5 | NTRK3 | 3.07617692 |
| 6 | MARK1 | 2.94855469 |
| 7 | EPHA4 | 2.85847583 |
| 8 | INSRR | 2.62169382 |
| 9 | STK38 | 2.53611221 |
| 10 | PLK2 | 2.51114848 |
| 11 | UHMK1 | 2.32733814 |
| 12 | PAK6 | 2.22549231 |
| 13 | SIK2 | 2.07846811 |
| 14 | DAPK2 | 1.99810378 |
| 15 | TNK2 | 1.98165276 |
| 16 | MAP4K2 | 1.96908729 |
| 17 | NTRK2 | 1.87197629 |
| 18 | MAP3K9 | 1.86201142 |
| 19 | RIPK4 | 1.77369718 |
| 20 | KSR2 | 1.76514126 |
| 21 | TYRO3 | 1.74213597 |
| 22 | PDK1 | 1.53888003 |
| 23 | NEK6 | 1.47574577 |
| 24 | PDPK1 | 1.46540782 |
| 25 | MARK2 | 1.42283574 |
| 26 | CAMKK1 | 1.40181281 |
| 27 | WNK1 | 1.37263679 |
| 28 | MAPK15 | 1.37055396 |
| 29 | MINK1 | 1.36305871 |
| 30 | LATS2 | 1.33095985 |
| 31 | CAMK1 | 1.24163067 |
| 32 | BRD4 | 1.23144817 |
| 33 | CAMK1G | 1.16539540 |
| 34 | MAP3K11 | 1.15136504 |
| 35 | FES | 1.15126582 |
| 36 | PRPF4B | 1.12039195 |
| 37 | CASK | 1.07757908 |
| 38 | PNCK | 1.01737426 |
| 39 | SGK223 | 1.01523271 |
| 40 | SGK494 | 1.01523271 |
| 41 | ARAF | 0.99804600 |
| 42 | DYRK1B | 0.98668995 |
| 43 | CDK5 | 0.96864039 |
| 44 | PRKCG | 0.93691859 |
| 45 | PKN1 | 0.88660670 |
| 46 | PRKCH | 0.87978849 |
| 47 | STK38L | 0.86404577 |
| 48 | CAMK4 | 0.83984864 |
| 49 | MAPK13 | 0.83076404 |
| 50 | NTRK1 | 0.82709812 |
| 51 | PHKG2 | 0.82243522 |
| 52 | PHKG1 | 0.82243522 |
| 53 | PRKG2 | 0.71611800 |
| 54 | GRK5 | 0.70012766 |
| 55 | MAP3K13 | 0.69367109 |
| 56 | MAPK12 | 0.62879408 |
| 57 | SGK2 | 0.61040208 |
| 58 | MAP3K2 | 0.61006033 |
| 59 | MAPK10 | 0.60908828 |
| 60 | RIPK1 | 0.59336898 |
| 61 | SGK1 | 0.59189328 |
| 62 | PTK2B | 0.58146557 |
| 63 | PRKCZ | 0.57978364 |
| 64 | CAMK2A | 0.56559323 |
| 65 | CDK19 | 0.55778509 |
| 66 | STK11 | 0.54896715 |
| 67 | PINK1 | 0.54674183 |
| 68 | MAP3K1 | 0.53641543 |
| 69 | PRKG1 | 0.53107780 |
| 70 | CAMK1D | 0.52198633 |
| 71 | ROCK1 | 0.52039156 |
| 72 | SGK3 | 0.51697057 |
| 73 | CDK11A | 0.50748187 |
| 74 | BRAF | 0.49809153 |
| 75 | RPS6KA2 | 0.49122157 |
| 76 | DYRK1A | 0.48433286 |
| 77 | CDK12 | 0.45342208 |
| 78 | JAK2 | 0.45055878 |
| 79 | GSK3B | 0.43651522 |
| 80 | MAPK8 | 0.43257188 |
| 81 | CDK14 | 0.41658513 |
| 82 | MAP3K7 | 0.40919585 |
| 83 | FYN | 0.40863294 |
| 84 | BRSK1 | 0.37725725 |
| 85 | MAP2K2 | 0.37606084 |
| 86 | RPS6KA3 | 0.35221925 |
| 87 | RPS6KA1 | 0.34632132 |
| 88 | SYK | 0.32257640 |
| 89 | CAMK2B | 0.31695910 |
| 90 | CDK15 | 0.30718068 |
| 91 | CAMK2G | 0.29937976 |
| 92 | CDK4 | 0.27495781 |
| 93 | PIK3CG | 0.27383892 |
| 94 | CDK7 | 0.26446206 |
| 95 | PRKCB | 0.26071854 |
| 96 | ROCK2 | 0.25888942 |
| 97 | CDK18 | 0.25869029 |
| 98 | RET | 0.25079123 |
| 99 | ALK | 0.24159970 |
| 100 | MAPK1 | 0.22012166 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.39713073 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.87111730 |
| 3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.84188965 |
| 4 | Olfactory transduction_Homo sapiens_hsa04740 | 2.66612191 |
| 5 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.46786845 |
| 6 | Morphine addiction_Homo sapiens_hsa05032 | 2.41785638 |
| 7 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.41727275 |
| 8 | Circadian entrainment_Homo sapiens_hsa04713 | 2.37600805 |
| 9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.12461874 |
| 10 | Long-term potentiation_Homo sapiens_hsa04720 | 2.12076667 |
| 11 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.06596628 |
| 12 | Insulin secretion_Homo sapiens_hsa04911 | 2.06382585 |
| 13 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.00948319 |
| 14 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.88772469 |
| 15 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.87200044 |
| 16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.80680254 |
| 17 | Salivary secretion_Homo sapiens_hsa04970 | 1.75232870 |
| 18 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.66651460 |
| 19 | Taste transduction_Homo sapiens_hsa04742 | 1.65998687 |
| 20 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.55664907 |
| 21 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.55315502 |
| 22 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.52446581 |
| 23 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.47435700 |
| 24 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.42676182 |
| 25 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.36606583 |
| 26 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.36193223 |
| 27 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.33855669 |
| 28 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.33636561 |
| 29 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.33374008 |
| 30 | Cocaine addiction_Homo sapiens_hsa05030 | 1.32859542 |
| 31 | Renin secretion_Homo sapiens_hsa04924 | 1.28094189 |
| 32 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.23593022 |
| 33 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.21392213 |
| 34 | Endocytosis_Homo sapiens_hsa04144 | 1.19964687 |
| 35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.12933615 |
| 36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.12525374 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.10754248 |
| 38 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.03400230 |
| 39 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.01786894 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.97456555 |
| 41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.96537406 |
| 42 | Allograft rejection_Homo sapiens_hsa05330 | 0.95353393 |
| 43 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.95249958 |
| 44 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.93428260 |
| 45 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.91146672 |
| 46 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.90064083 |
| 47 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.89871378 |
| 48 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.88904677 |
| 49 | Glioma_Homo sapiens_hsa05214 | 0.88414164 |
| 50 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.87515212 |
| 51 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.86880850 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.86811198 |
| 53 | Phototransduction_Homo sapiens_hsa04744 | 0.85927066 |
| 54 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.85644757 |
| 55 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.84069045 |
| 56 | Long-term depression_Homo sapiens_hsa04730 | 0.82666259 |
| 57 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.81244747 |
| 58 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.81232563 |
| 59 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.80545904 |
| 60 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.79102153 |
| 61 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.76385706 |
| 62 | Melanogenesis_Homo sapiens_hsa04916 | 0.75749859 |
| 63 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.75416961 |
| 64 | Bile secretion_Homo sapiens_hsa04976 | 0.74920644 |
| 65 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.73703719 |
| 66 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.72384990 |
| 67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.70265486 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64729821 |
| 69 | Viral myocarditis_Homo sapiens_hsa05416 | 0.63125782 |
| 70 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.62821315 |
| 71 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.62696577 |
| 72 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.60686126 |
| 73 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59029853 |
| 74 | Gap junction_Homo sapiens_hsa04540 | 0.58385799 |
| 75 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58292483 |
| 76 | Prion diseases_Homo sapiens_hsa05020 | 0.56368668 |
| 77 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.56256227 |
| 78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.56222399 |
| 79 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.55692235 |
| 80 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.54280945 |
| 81 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.53366072 |
| 82 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.53092809 |
| 83 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50228605 |
| 84 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.48333411 |
| 85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.44909656 |
| 86 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.43229046 |
| 87 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.42214066 |
| 88 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.41810324 |
| 89 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41710174 |
| 90 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.41519856 |
| 91 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.40281333 |
| 92 | Axon guidance_Homo sapiens_hsa04360 | 0.39648859 |
| 93 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.38951514 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.35242675 |
| 95 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.34876249 |
| 96 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.34640129 |
| 97 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.33854553 |
| 98 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.33364319 |
| 99 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.33294698 |
| 100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.31122659 |

