RUFY2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.28036620
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.10479605
3vocalization behavior (GO:0071625)4.83081926
4pyrimidine nucleobase catabolic process (GO:0006208)4.82106059
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.79002949
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.63295168
7synaptic vesicle exocytosis (GO:0016079)4.59710372
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.57662563
9locomotory exploration behavior (GO:0035641)4.51650690
10regulation of synaptic vesicle exocytosis (GO:2000300)4.42335388
11synaptic vesicle maturation (GO:0016188)4.40983514
12neuronal action potential propagation (GO:0019227)4.34834688
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.32440043
14glutamate secretion (GO:0014047)4.27473691
15behavioral response to nicotine (GO:0035095)4.21162477
16protein localization to synapse (GO:0035418)4.17715303
17presynaptic membrane assembly (GO:0097105)4.08793439
18regulation of glutamate receptor signaling pathway (GO:1900449)4.06226989
19glutamate receptor signaling pathway (GO:0007215)3.98690365
20nucleobase catabolic process (GO:0046113)3.96960465
21synaptic transmission, glutamatergic (GO:0035249)3.92249821
22presynaptic membrane organization (GO:0097090)3.86533470
23neuron-neuron synaptic transmission (GO:0007270)3.85444448
24regulation of synaptic vesicle transport (GO:1902803)3.81250336
25regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.80698507
26neurotransmitter secretion (GO:0007269)3.74879847
27synaptic vesicle docking involved in exocytosis (GO:0016081)3.73376926
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.71348963
29regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.70810808
30transmission of nerve impulse (GO:0019226)3.66957943
31neuron recognition (GO:0008038)3.66920052
32exploration behavior (GO:0035640)3.62809118
33gamma-aminobutyric acid transport (GO:0015812)3.59100662
34negative regulation of cytosolic calcium ion concentration (GO:0051481)3.57085047
35cerebellar Purkinje cell differentiation (GO:0021702)3.55389042
36regulation of excitatory postsynaptic membrane potential (GO:0060079)3.51579127
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.49844702
38postsynaptic membrane organization (GO:0001941)3.49775285
39gamma-aminobutyric acid signaling pathway (GO:0007214)3.46052997
40regulation of neuronal synaptic plasticity (GO:0048168)3.44966643
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.40785818
42membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.40616270
43regulation of postsynaptic membrane potential (GO:0060078)3.39912158
44negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.39785108
45dendritic spine morphogenesis (GO:0060997)3.37414188
46axonal fasciculation (GO:0007413)3.36862481
47positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.35884441
48positive regulation of membrane potential (GO:0045838)3.34223049
49behavioral response to ethanol (GO:0048149)3.33136841
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.31067629
51regulation of neurotransmitter secretion (GO:0046928)3.30171070
52protein polyglutamylation (GO:0018095)3.29293121
53long-term memory (GO:0007616)3.28448706
54neurotransmitter transport (GO:0006836)3.27720849
55membrane depolarization during action potential (GO:0086010)3.27030709
56regulation of respiratory system process (GO:0044065)3.21846096
57adult walking behavior (GO:0007628)3.20899262
58layer formation in cerebral cortex (GO:0021819)3.20251945
59negative regulation of neurotransmitter transport (GO:0051589)3.18924275
60epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.18511248
61synaptic vesicle endocytosis (GO:0048488)3.17367153
62epithelial cilium movement (GO:0003351)3.16696644
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.16543173
64cerebellar granule cell differentiation (GO:0021707)3.14753121
65synapse assembly (GO:0007416)3.14591622
66somite development (GO:0061053)3.13794795
67regulation of vesicle fusion (GO:0031338)3.12201998
68neural tube formation (GO:0001841)3.12198163
69membrane depolarization (GO:0051899)3.11424154
70limb bud formation (GO:0060174)3.10336142
71regulation of synapse structural plasticity (GO:0051823)3.10240836
72membrane hyperpolarization (GO:0060081)3.09895421
73response to pheromone (GO:0019236)3.09322259
74regulation of neurotransmitter transport (GO:0051588)3.06138618
75cellular potassium ion homeostasis (GO:0030007)3.04736646
76dendrite morphogenesis (GO:0048813)3.04095507
77proline transport (GO:0015824)3.03558175
78positive regulation of synaptic transmission, GABAergic (GO:0032230)3.03341367
79neurotransmitter-gated ion channel clustering (GO:0072578)3.02537229
80regulation of respiratory gaseous exchange (GO:0043576)3.02471918
81retinal cone cell development (GO:0046549)3.00581530
82positive regulation of synapse assembly (GO:0051965)3.00174836
83long-term synaptic potentiation (GO:0060291)3.00039254
84axon ensheathment in central nervous system (GO:0032291)2.99993425
85central nervous system myelination (GO:0022010)2.99993425
86cell migration in hindbrain (GO:0021535)2.99538038
87neuronal ion channel clustering (GO:0045161)2.96691222
88regulation of dendritic spine morphogenesis (GO:0061001)2.96323686
89regulation of neurotransmitter levels (GO:0001505)2.95886677
90regulation of synaptic plasticity (GO:0048167)2.93028164
91regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.92095194
92startle response (GO:0001964)2.88772487
93regulation of voltage-gated calcium channel activity (GO:1901385)2.87317223
94detection of calcium ion (GO:0005513)2.86117158
95mating behavior (GO:0007617)2.85654316
96neuronal action potential (GO:0019228)2.84850796
97learning (GO:0007612)2.82139292
98cell differentiation in hindbrain (GO:0021533)2.82097385
99innervation (GO:0060384)2.81958151
100nonmotile primary cilium assembly (GO:0035058)2.81822583
101regulation of synaptic transmission, GABAergic (GO:0032228)2.81365264
102prepulse inhibition (GO:0060134)2.80999354
103C4-dicarboxylate transport (GO:0015740)2.80690778
104protein localization to cilium (GO:0061512)2.79219991
105glycine transport (GO:0015816)2.78696332
106neuromuscular synaptic transmission (GO:0007274)2.78695107
107regulation of action potential (GO:0098900)2.77562929
108synaptic transmission (GO:0007268)2.76919927
109positive regulation of neurotransmitter transport (GO:0051590)2.76673469
110positive regulation of neurotransmitter secretion (GO:0001956)2.76276726
111detection of light stimulus involved in sensory perception (GO:0050962)2.75311805
112detection of light stimulus involved in visual perception (GO:0050908)2.75311805
113mechanosensory behavior (GO:0007638)2.75163441
114positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.75035519
115detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.75016132
116cerebral cortex radially oriented cell migration (GO:0021799)2.74030442
117neuromuscular process controlling posture (GO:0050884)2.72618354
118negative regulation of dendrite morphogenesis (GO:0050774)2.72434442
119central nervous system projection neuron axonogenesis (GO:0021952)2.72246213
120righting reflex (GO:0060013)2.71013246
121long-chain fatty acid biosynthetic process (GO:0042759)2.70808060
122response to histamine (GO:0034776)2.70767012
123auditory behavior (GO:0031223)2.70336727
124retinal ganglion cell axon guidance (GO:0031290)2.69369455
125cilium movement (GO:0003341)2.69329717
126intraciliary transport (GO:0042073)2.68920874
127atrial cardiac muscle cell action potential (GO:0086014)2.66318138
128calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.66147154
129axoneme assembly (GO:0035082)2.64785514
130positive regulation of action potential (GO:0045760)2.63165093
131spinal cord development (GO:0021510)2.60168194
132serotonin metabolic process (GO:0042428)2.59941764
133action potential (GO:0001508)2.59917052
134spinal cord motor neuron differentiation (GO:0021522)2.59681757
135cilium organization (GO:0044782)2.59201733
136head development (GO:0060322)2.59058456
137cilium morphogenesis (GO:0060271)2.56941612
138central nervous system neuron axonogenesis (GO:0021955)2.55746183
139primary amino compound metabolic process (GO:1901160)2.55609949
140cilium assembly (GO:0042384)2.55436994
141negative regulation of transcription regulatory region DNA binding (GO:2000678)2.54973631
142sympathetic nervous system development (GO:0048485)2.50354459
143positive regulation of mitochondrial fission (GO:0090141)2.49555885
144regulation of cilium movement (GO:0003352)2.49132968
145cilium or flagellum-dependent cell motility (GO:0001539)2.48597296
146photoreceptor cell development (GO:0042461)2.47336493
147glycosphingolipid biosynthetic process (GO:0006688)2.46494690
148regulation of neurotransmitter uptake (GO:0051580)2.44699006
149positive regulation of potassium ion transmembrane transport (GO:1901381)2.44356971
150olfactory bulb development (GO:0021772)2.41973251
151negative regulation of mast cell activation (GO:0033004)2.41179659
152establishment of mitochondrion localization (GO:0051654)2.40165356
153establishment of protein localization to Golgi (GO:0072600)2.39012774
154hindbrain development (GO:0030902)2.36648718
155cornea development in camera-type eye (GO:0061303)2.36107795
156forebrain neuron differentiation (GO:0021879)2.35480709
157negative regulation of oligodendrocyte differentiation (GO:0048715)2.35336545
158regulation of collateral sprouting (GO:0048670)2.34650111

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.23136953
2GBX2_23144817_ChIP-Seq_PC3_Human4.09504552
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.90642423
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.82513593
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.76258237
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.48256657
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.48256657
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.40466283
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.39662069
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.37029210
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35058730
12REST_21632747_ChIP-Seq_MESCs_Mouse2.31556633
13TAF15_26573619_Chip-Seq_HEK293_Human2.31383383
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.29779758
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.27929202
16DROSHA_22980978_ChIP-Seq_HELA_Human2.24858665
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22654359
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.18307091
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.17733318
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.01034784
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.00193894
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.99972125
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.97108751
24SUZ12_27294783_Chip-Seq_ESCs_Mouse1.93850127
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.88908432
26EWS_26573619_Chip-Seq_HEK293_Human1.88280216
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.86975800
28AR_21572438_ChIP-Seq_LNCaP_Human1.86755586
29* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.85749012
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85585351
31SMAD4_21799915_ChIP-Seq_A2780_Human1.82244826
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81827768
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81806649
34RARB_27405468_Chip-Seq_BRAIN_Mouse1.80807427
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.78653899
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.75182277
37P300_19829295_ChIP-Seq_ESCs_Human1.73615925
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67824605
39BMI1_23680149_ChIP-Seq_NPCS_Mouse1.66918197
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65561471
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.64579664
42IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.57407464
43CBP_20019798_ChIP-Seq_JUKART_Human1.57407464
44NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.55043560
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53948622
46GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.53754624
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.52590027
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.50549045
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50265735
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.49614778
51STAT3_23295773_ChIP-Seq_U87_Human1.44584019
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44261816
53RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41758701
54TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41474253
55IGF1R_20145208_ChIP-Seq_DFB_Human1.40607461
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40451055
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39240320
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38799858
59MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37057346
60BCAT_22108803_ChIP-Seq_LS180_Human1.36735176
61AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34258583
62ZNF274_21170338_ChIP-Seq_K562_Hela1.32816669
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32599157
64RNF2_27304074_Chip-Seq_NSC_Mouse1.30725041
65FUS_26573619_Chip-Seq_HEK293_Human1.30351335
66AR_25329375_ChIP-Seq_VCAP_Human1.28569910
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.28518044
68TCF4_23295773_ChIP-Seq_U87_Human1.27884816
69CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27384283
70RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25714137
71ER_23166858_ChIP-Seq_MCF-7_Human1.25363115
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24902989
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23017566
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22328326
75VDR_22108803_ChIP-Seq_LS180_Human1.21856125
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.21399269
77VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.20156031
78PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19252533
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17957136
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.17870209
81HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17195982
82TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16873054
83EZH2_27294783_Chip-Seq_NPCs_Mouse1.16269338
84AHR_22903824_ChIP-Seq_MCF-7_Human1.16139229
85KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15933855
86RUNX2_22187159_ChIP-Seq_PCA_Human1.15425382
87ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14784246
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14487612
89TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14487612
90* FLI1_21867929_ChIP-Seq_TH2_Mouse1.14225733
91TP53_22573176_ChIP-Seq_HFKS_Human1.13724666
92FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.12963748
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.11776056
94TCF4_22108803_ChIP-Seq_LS180_Human1.11551093
95AR_19668381_ChIP-Seq_PC3_Human1.11424789
96CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11005318
97EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.10984167
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10456135
99RING1B_27294783_Chip-Seq_ESCs_Mouse1.09291916
100PRDM14_20953172_ChIP-Seq_ESCs_Human1.09091594
101TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08855430
102E2F1_18555785_Chip-Seq_ESCs_Mouse1.07979246
103EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07035725
104YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06862026
105NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06263389
106NFE2_27457419_Chip-Seq_LIVER_Mouse1.06034308
107TP53_16413492_ChIP-PET_HCT116_Human1.05883127
108SMAD4_21741376_ChIP-Seq_EPCs_Human1.05714703
109CMYC_18555785_Chip-Seq_ESCs_Mouse1.05001535
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04438037
111MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04015774
112TP53_18474530_ChIP-ChIP_U2OS_Human1.02626943
113FLI1_27457419_Chip-Seq_LIVER_Mouse1.01528493
114PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00487755
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00324649
116WT1_25993318_ChIP-Seq_PODOCYTE_Human0.99733703
117JUN_21703547_ChIP-Seq_K562_Human0.99535712
118MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99397663
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99242704
120P53_22387025_ChIP-Seq_ESCs_Mouse0.98837514
121BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.98390490
122RING1B_27294783_Chip-Seq_NPCs_Mouse0.97423122

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.00022364
2MP0003880_abnormal_central_pattern4.69149383
3MP0003635_abnormal_synaptic_transmissio3.56467888
4MP0004270_analgesia3.49861456
5MP0001968_abnormal_touch/_nociception3.20079904
6MP0009046_muscle_twitch3.18444400
7MP0005423_abnormal_somatic_nervous3.13361883
8MP0009745_abnormal_behavioral_response3.07598437
9MP0002064_seizures2.93044884
10MP0002063_abnormal_learning/memory/cond2.79606986
11MP0002735_abnormal_chemical_nociception2.79086979
12MP0002734_abnormal_mechanical_nocicepti2.72673288
13MP0002272_abnormal_nervous_system2.71093119
14MP0002572_abnormal_emotion/affect_behav2.60608319
15MP0001486_abnormal_startle_reflex2.58807927
16MP0002736_abnormal_nociception_after2.54864726
17MP0008877_abnormal_DNA_methylation2.49287711
18MP0002102_abnormal_ear_morphology2.37306523
19MP0006276_abnormal_autonomic_nervous2.21225982
20MP0002067_abnormal_sensory_capabilities2.20501575
21MP0002733_abnormal_thermal_nociception2.14871527
22MP0001440_abnormal_grooming_behavior2.14680281
23MP0002184_abnormal_innervation2.07840171
24MP0002822_catalepsy2.07015209
25MP0001970_abnormal_pain_threshold2.06234596
26MP0000778_abnormal_nervous_system2.05265647
27MP0001501_abnormal_sleep_pattern2.01585314
28MP0001984_abnormal_olfaction1.89081014
29MP0008569_lethality_at_weaning1.87059345
30MP0005645_abnormal_hypothalamus_physiol1.85520742
31MP0001188_hyperpigmentation1.80594243
32MP0002557_abnormal_social/conspecific_i1.78082828
33MP0005386_behavior/neurological_phenoty1.77047611
34MP0004924_abnormal_behavior1.77047611
35MP0003787_abnormal_imprinting1.70310766
36MP0005646_abnormal_pituitary_gland1.70089679
37MP0001529_abnormal_vocalization1.65305112
38MP0004742_abnormal_vestibular_system1.63433019
39MP0001905_abnormal_dopamine_level1.62280724
40MP0004142_abnormal_muscle_tone1.61580480
41MP0000955_abnormal_spinal_cord1.55860920
42MP0004858_abnormal_nervous_system1.52358856
43MP0002882_abnormal_neuron_morphology1.49838731
44MP0004811_abnormal_neuron_physiology1.49371183
45MP0005187_abnormal_penis_morphology1.46295444
46MP0009780_abnormal_chondrocyte_physiolo1.45600850
47MP0002234_abnormal_pharynx_morphology1.39900034
48MP0002066_abnormal_motor_capabilities/c1.37292336
49MP0005409_darkened_coat_color1.35079598
50MP0004885_abnormal_endolymph1.32512351
51MP0003890_abnormal_embryonic-extraembry1.31839622
52MP0001502_abnormal_circadian_rhythm1.31823979
53MP0000920_abnormal_myelination1.30211145
54MP0002837_dystrophic_cardiac_calcinosis1.29444592
55MP0001986_abnormal_taste_sensitivity1.29307755
56MP0003122_maternal_imprinting1.28226838
57MP0005551_abnormal_eye_electrophysiolog1.27427361
58MP0000569_abnormal_digit_pigmentation1.24517181
59MP0003633_abnormal_nervous_system1.23169046
60MP0004133_heterotaxia1.22265539
61MP0010386_abnormal_urinary_bladder1.21128415
62MP0000049_abnormal_middle_ear1.19932447
63MP0000427_abnormal_hair_cycle1.18443333
64MP0003195_calcinosis1.18162389
65MP0002229_neurodegeneration1.16959807
66MP0003329_amyloid_beta_deposits1.14331420
67MP0003631_nervous_system_phenotype1.12697482
68MP0004145_abnormal_muscle_electrophysio1.11917189
69MP0002653_abnormal_ependyma_morphology1.09363746
70MP0001963_abnormal_hearing_physiology1.08783589
71MP0003879_abnormal_hair_cell1.08647983
72MP0002152_abnormal_brain_morphology1.08324017
73MP0002909_abnormal_adrenal_gland1.08266976
74MP0002638_abnormal_pupillary_reflex1.04571696
75MP0003119_abnormal_digestive_system1.04543916
76MP0002752_abnormal_somatic_nervous1.04413071
77MP0003634_abnormal_glial_cell1.04043393
78MP0005195_abnormal_posterior_eye1.03865853
79MP0004043_abnormal_pH_regulation1.03025532
80MP0006292_abnormal_olfactory_placode1.01903206
81MP0000631_abnormal_neuroendocrine_gland1.00722405
82MP0001485_abnormal_pinna_reflex1.00690751
83MP0000647_abnormal_sebaceous_gland1.00196381
84MP0005171_absent_coat_pigmentation0.99383564
85MP0001299_abnormal_eye_distance/0.96111691
86MP0005394_taste/olfaction_phenotype0.94976738
87MP0005499_abnormal_olfactory_system0.94976738
88MP0008995_early_reproductive_senescence0.94251605
89MP0003632_abnormal_nervous_system0.92319560
90MP0002160_abnormal_reproductive_system0.90814525
91MP0006072_abnormal_retinal_apoptosis0.90774099
92MP0003011_delayed_dark_adaptation0.89170589
93MP0003937_abnormal_limbs/digits/tail_de0.88380889
94MP0003646_muscle_fatigue0.86948139
95MP0005367_renal/urinary_system_phenotyp0.84404804
96MP0000516_abnormal_urinary_system0.84404804
97MP0002069_abnormal_eating/drinking_beha0.82560311
98MP0000383_abnormal_hair_follicle0.81653456
99MP0003690_abnormal_glial_cell0.80336575
100MP0004215_abnormal_myocardial_fiber0.79703357
101MP0002751_abnormal_autonomic_nervous0.79554073
102MP0003698_abnormal_male_reproductive0.79391867
103MP0000026_abnormal_inner_ear0.75729119
104MP0004085_abnormal_heartbeat0.75471924
105MP0008872_abnormal_physiological_respon0.74612816
106MP0005253_abnormal_eye_physiology0.73722555
107MP0001177_atelectasis0.70562862
108MP0008874_decreased_physiological_sensi0.67493612
109MP0001943_abnormal_respiration0.63214446
110MP0002090_abnormal_vision0.62868735
111MP0002876_abnormal_thyroid_physiology0.62071182
112MP0001664_abnormal_digestion0.61261940
113MP0003861_abnormal_nervous_system0.60945753
114MP0000015_abnormal_ear_pigmentation0.60103422
115MP0005623_abnormal_meninges_morphology0.59619646
116MP0003121_genomic_imprinting0.57597124
117MP0008260_abnormal_autophagy0.56068939
118MP0002082_postnatal_lethality0.55005635
119MP0010770_preweaning_lethality0.55005635
120MP0010769_abnormal_survival0.54306614
121MP0005535_abnormal_body_temperature0.53969230
122MP0005379_endocrine/exocrine_gland_phen0.52924202
123MP0008789_abnormal_olfactory_epithelium0.51575584
124MP0004484_altered_response_of0.51225822
125MP0003938_abnormal_ear_development0.51148997

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.57993295
2Myokymia (HP:0002411)5.40372092
3Focal seizures (HP:0007359)5.05984324
4Febrile seizures (HP:0002373)4.60695697
5Progressive cerebellar ataxia (HP:0002073)4.54096552
6Atonic seizures (HP:0010819)4.46995585
7Epileptic encephalopathy (HP:0200134)4.40059181
8Pancreatic cysts (HP:0001737)3.99631533
9Visual hallucinations (HP:0002367)3.91483703
10Pancreatic fibrosis (HP:0100732)3.90511758
11True hermaphroditism (HP:0010459)3.87866089
12Action tremor (HP:0002345)3.83920574
13Broad-based gait (HP:0002136)3.65397462
14Abnormality of midbrain morphology (HP:0002418)3.59209801
15Molar tooth sign on MRI (HP:0002419)3.59209801
16Absence seizures (HP:0002121)3.53038301
17Nephronophthisis (HP:0000090)3.50216781
18Gaze-evoked nystagmus (HP:0000640)3.46118662
19Supranuclear gaze palsy (HP:0000605)3.31189373
20Dialeptic seizures (HP:0011146)3.30842641
21Generalized tonic-clonic seizures (HP:0002069)3.17603634
22Limb dystonia (HP:0002451)3.17593102
23Ankle clonus (HP:0011448)3.16090876
24Abnormality of the renal medulla (HP:0100957)3.12385106
25Hyperventilation (HP:0002883)3.06220609
26Abnormality of the corticospinal tract (HP:0002492)3.03392399
27Dysmetria (HP:0001310)3.01194147
28Truncal ataxia (HP:0002078)2.99182264
29Congenital stationary night blindness (HP:0007642)2.94888541
30Chronic hepatic failure (HP:0100626)2.94621738
31Scanning speech (HP:0002168)2.94584631
32Lissencephaly (HP:0001339)2.91248487
33Dysdiadochokinesis (HP:0002075)2.81411837
34Cystic liver disease (HP:0006706)2.76951791
35Excessive salivation (HP:0003781)2.72187075
36Drooling (HP:0002307)2.72187075
37Abnormality of the renal cortex (HP:0011035)2.72140939
38Insidious onset (HP:0003587)2.69595276
39Termporal pattern (HP:0011008)2.69595276
40Degeneration of the lateral corticospinal tracts (HP:0002314)2.69317244
41Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.69317244
42Spastic gait (HP:0002064)2.67648394
43Genetic anticipation (HP:0003743)2.64578686
44Abnormality of binocular vision (HP:0011514)2.64374125
45Diplopia (HP:0000651)2.64374125
46Urinary bladder sphincter dysfunction (HP:0002839)2.61639384
47Absent speech (HP:0001344)2.58049580
48Amblyopia (HP:0000646)2.54799635
49Progressive inability to walk (HP:0002505)2.52616150
50Polyphagia (HP:0002591)2.48158805
51Type II lissencephaly (HP:0007260)2.45572743
52Depression (HP:0000716)2.44367427
53Retinal dysplasia (HP:0007973)2.44096192
54Pheochromocytoma (HP:0002666)2.44018100
55Pachygyria (HP:0001302)2.43283697
56Hypothermia (HP:0002045)2.41805481
57Poor eye contact (HP:0000817)2.41589891
58Ulnar claw (HP:0001178)2.41507142
59Hemiparesis (HP:0001269)2.41026842
60Pendular nystagmus (HP:0012043)2.40626186
61Impaired vibration sensation in the lower limbs (HP:0002166)2.40032556
62Abnormality of the labia minora (HP:0012880)2.38056634
63Anxiety (HP:0000739)2.37975312
64Neurofibrillary tangles (HP:0002185)2.37868590
65Mutism (HP:0002300)2.32222472
66Aplasia/Hypoplasia of the tongue (HP:0010295)2.30017882
67Sclerocornea (HP:0000647)2.28068304
68Epileptiform EEG discharges (HP:0011182)2.23218631
69Gait imbalance (HP:0002141)2.22013830
70Urinary urgency (HP:0000012)2.21079269
71Poor coordination (HP:0002370)2.18949065
72Volvulus (HP:0002580)2.17893769
73EEG with generalized epileptiform discharges (HP:0011198)2.17655530
74Intention tremor (HP:0002080)2.16823744
75Aplasia/Hypoplasia of the tibia (HP:0005772)2.16593968
76Abnormal eating behavior (HP:0100738)2.15477419
77Impaired smooth pursuit (HP:0007772)2.14089674
78Postural instability (HP:0002172)2.13523111
79Agitation (HP:0000713)2.10821818
80Neuroendocrine neoplasm (HP:0100634)2.10781698
81Peripheral hypomyelination (HP:0007182)2.10558162
82Impaired social interactions (HP:0000735)2.10078532
83Abnormal social behavior (HP:0012433)2.10078532
84Intestinal atresia (HP:0011100)2.08715878
85Abnormal hair whorl (HP:0010721)2.08595970
86Cerebral inclusion bodies (HP:0100314)2.08145623
87Abnormality of salivation (HP:0100755)2.06552844
88Anencephaly (HP:0002323)2.06317040
89Protruding tongue (HP:0010808)2.06277904
90Thyroid-stimulating hormone excess (HP:0002925)2.05758179
91Postaxial foot polydactyly (HP:0001830)2.05691260
92Attenuation of retinal blood vessels (HP:0007843)2.05424301
93Blue irides (HP:0000635)2.05317460
94Postaxial hand polydactyly (HP:0001162)2.04102404
95Aqueductal stenosis (HP:0002410)2.02249333
96Hypsarrhythmia (HP:0002521)2.01946562
97Lower limb muscle weakness (HP:0007340)2.01675595
98Abolished electroretinogram (ERG) (HP:0000550)2.01390541
99Specific learning disability (HP:0001328)1.98492297
100Hip dysplasia (HP:0001385)1.98304480
101Inability to walk (HP:0002540)1.96915139
102Keratoconus (HP:0000563)1.96736750
103Increased corneal curvature (HP:0100692)1.96736750
104Renal cortical cysts (HP:0000803)1.96280896
105Oligodactyly (hands) (HP:0001180)1.95700300
106Onion bulb formation (HP:0003383)1.94836233
107Congenital hepatic fibrosis (HP:0002612)1.94541140
108Exotropia (HP:0000577)1.94088001
109Genital tract atresia (HP:0001827)1.93581571
110Bony spicule pigmentary retinopathy (HP:0007737)1.91758426
111Medial flaring of the eyebrow (HP:0010747)1.90699242
112Abnormality of ocular smooth pursuit (HP:0000617)1.90544009
113Dynein arm defect of respiratory motile cilia (HP:0012255)1.90087443
114Absent/shortened dynein arms (HP:0200106)1.90087443
115Male pseudohermaphroditism (HP:0000037)1.88298654
116Short foot (HP:0001773)1.87791317
117Vaginal atresia (HP:0000148)1.86651709
118Stereotypic behavior (HP:0000733)1.86490400
119Widely spaced teeth (HP:0000687)1.86278635
120Small hand (HP:0200055)1.85959990
121Cerebellar dysplasia (HP:0007033)1.85220934
122Tubular atrophy (HP:0000092)1.83706541
123Papilledema (HP:0001085)1.83659514
124Abnormal respiratory motile cilium morphology (HP:0005938)1.83342648
125Abnormal respiratory epithelium morphology (HP:0012253)1.83342648
126Akinesia (HP:0002304)1.82852315
127Steppage gait (HP:0003376)1.82361150
128Congenital primary aphakia (HP:0007707)1.81124709
129Tubulointerstitial nephritis (HP:0001970)1.80900107
130Hemiplegia (HP:0002301)1.80381747
131Optic nerve hypoplasia (HP:0000609)1.80190913
132Fetal akinesia sequence (HP:0001989)1.80105938
133Polydipsia (HP:0001959)1.79773144
134Abnormal drinking behavior (HP:0030082)1.79773144
135Narrow forehead (HP:0000341)1.78976742
136Bradykinesia (HP:0002067)1.78383731
137Preaxial hand polydactyly (HP:0001177)1.77813549
138Occipital encephalocele (HP:0002085)1.77597858
139Methylmalonic acidemia (HP:0002912)1.77373018
140Furrowed tongue (HP:0000221)1.76990785
141Tented upper lip vermilion (HP:0010804)1.76174790
142Nephrogenic diabetes insipidus (HP:0009806)1.75519093
143Hypoplasia of the brainstem (HP:0002365)1.75438990
144Aplasia/Hypoplasia of the brainstem (HP:0007362)1.75438990
145Hypoventilation (HP:0002791)1.75091810
146Abnormal ciliary motility (HP:0012262)1.75006106
147Bradycardia (HP:0001662)1.74779340
148Gait ataxia (HP:0002066)1.74672199
149Abnormal rod and cone electroretinograms (HP:0008323)1.73611472
150Decreased central vision (HP:0007663)1.73279338
151Gastroesophageal reflux (HP:0002020)1.72651640
152Esotropia (HP:0000565)1.71912300
153Morphological abnormality of the middle ear (HP:0008609)1.69646971
154Thickened helices (HP:0000391)1.67535114
155Psychosis (HP:0000709)1.67272718
156Incomplete penetrance (HP:0003829)1.67007232
157Aplasia/Hypoplasia of the patella (HP:0006498)1.66796289
158Torticollis (HP:0000473)1.65047862
159Neuronal loss in central nervous system (HP:0002529)1.64918324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.18573715
2FRK4.11307667
3CASK3.42497427
4EPHA43.09485269
5MARK12.94917845
6MAP3K42.84930336
7MAP2K72.56177940
8MAP3K92.51038422
9MAP4K22.34147976
10MINK12.18887905
11TNIK2.12222670
12MAP3K121.99343872
13MAPK131.91477188
14NTRK21.89642894
15PRPF4B1.88593411
16TRIM281.83979573
17GRK11.82945412
18NTRK11.81777494
19PNCK1.79598011
20PAK61.79225836
21NUAK11.69764759
22MAP2K41.56324094
23ERBB31.54228500
24RIPK41.54058688
25DAPK21.52311145
26PLK21.50823799
27SIK21.45322661
28DYRK21.44751459
29OXSR11.42731171
30GRK51.38503812
31SGK2231.38471527
32SGK4941.38471527
33STK391.36370697
34UHMK11.35430740
35CDK51.34625527
36WNK11.26054161
37CAMKK21.25036007
38EPHA31.15203249
39KSR21.14681760
40CSNK1G21.14123253
41CDK191.13845096
42CAMK2A1.11315918
43SGK21.10703390
44ACVR1B1.09735138
45ARAF1.06999057
46NEK61.06311475
47CAMK2B1.04577529
48PHKG21.03489283
49PHKG11.03489283
50KSR11.03350164
51CAMKK11.00409779
52FES0.99410520
53PRKCG0.98968428
54SIK30.98039544
55STK38L0.97232776
56MAP3K130.95763826
57MAPKAPK50.95749689
58PKN10.95482049
59MKNK20.94510434
60ZAK0.93047822
61DYRK1A0.91702117
62STK380.89488035
63PRKD30.88699004
64MARK20.88180447
65CSNK1G30.87007686
66FGFR20.86325911
67MAP3K20.85749375
68TLK10.85454250
69BCR0.84116479
70CSNK1A1L0.80275325
71CAMK1G0.80233943
72PRKCH0.79432642
73PRKCE0.78930877
74CAMK10.78897516
75PAK30.78682396
76BMPR20.78177025
77DAPK10.76970779
78TNK20.75896059
79SGK30.75525509
80TAOK30.75389927
81SGK10.74429405
82CAMK2D0.74214803
83AKT30.73334573
84CDK180.73124770
85CDK140.71245900
86CDK150.69530064
87LATS10.68599631
88MUSK0.68088753
89FGR0.66490987
90GRK70.64223890
91STK110.63032358
92STK160.61786893
93INSRR0.61495142
94BMPR1B0.61388210
95ROCK20.60977804
96CDC42BPA0.60668737
97PLK40.60345150
98CDK11A0.60001850
99YES10.59826438
100RET0.58910500
101BCKDK0.57629513
102CAMK2G0.57344418
103ADRBK20.56796656
104TYRO30.56283448
105CSNK1G10.56182331
106PRKG10.52449475
107CSNK1D0.51277310
108DMPK0.51235470
109PINK10.51215541
110FYN0.51094000
111PRKCZ0.49720846
112PRKAA10.49307255
113RAF10.49215690
114MAPK100.48907446
115PRKACA0.48764710
116PTK2B0.48663410
117CCNB10.48172208
118DYRK30.48083903
119LATS20.47167509
120CSNK1A10.45961377
121FER0.45731488
122EPHB20.45482020
123TGFBR10.43873159
124ADRBK10.43207598
125LIMK10.42538838
126RPS6KA30.41790342
127CDK30.41696729
128WNK40.39946793
129CAMK40.39256212
130WNK30.39050911
131CSNK1E0.36336980
132VRK10.35739985
133PRKACB0.32514294
134PIK3CA0.31502520
135ERBB20.30544253
136MKNK10.29486748
137MAPK150.29381338

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.74483221
2Synaptic vesicle cycle_Homo sapiens_hsa047213.02523281
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.74124858
4GABAergic synapse_Homo sapiens_hsa047272.61137160
5Glutamatergic synapse_Homo sapiens_hsa047242.60727831
6Olfactory transduction_Homo sapiens_hsa047402.59713926
7Circadian entrainment_Homo sapiens_hsa047132.57273223
8Morphine addiction_Homo sapiens_hsa050322.55154454
9Long-term potentiation_Homo sapiens_hsa047202.32662655
10Amphetamine addiction_Homo sapiens_hsa050312.22238172
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.20828754
12Taste transduction_Homo sapiens_hsa047422.17745343
13Dopaminergic synapse_Homo sapiens_hsa047282.15034638
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.05842837
15Serotonergic synapse_Homo sapiens_hsa047262.04704172
16Salivary secretion_Homo sapiens_hsa049702.03503935
17Insulin secretion_Homo sapiens_hsa049111.98807857
18Cholinergic synapse_Homo sapiens_hsa047251.89792592
19Long-term depression_Homo sapiens_hsa047301.87619697
20Butanoate metabolism_Homo sapiens_hsa006501.83055566
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.77825375
22Protein export_Homo sapiens_hsa030601.75383098
23Cocaine addiction_Homo sapiens_hsa050301.70338862
24Gastric acid secretion_Homo sapiens_hsa049711.65105063
25Collecting duct acid secretion_Homo sapiens_hsa049661.62477747
26Renin secretion_Homo sapiens_hsa049241.58941948
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.57676172
28Calcium signaling pathway_Homo sapiens_hsa040201.55149644
29Phototransduction_Homo sapiens_hsa047441.48068376
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.46894743
31Nitrogen metabolism_Homo sapiens_hsa009101.46541712
32Oxytocin signaling pathway_Homo sapiens_hsa049211.45813469
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.44970059
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.43850314
35Axon guidance_Homo sapiens_hsa043601.40330801
36Linoleic acid metabolism_Homo sapiens_hsa005911.40045233
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.37713523
38Basal transcription factors_Homo sapiens_hsa030221.29907695
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.29264674
40GnRH signaling pathway_Homo sapiens_hsa049121.27801351
41Propanoate metabolism_Homo sapiens_hsa006401.25896081
42alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.25281415
43Fanconi anemia pathway_Homo sapiens_hsa034601.25237538
44Gap junction_Homo sapiens_hsa045401.24442321
45cAMP signaling pathway_Homo sapiens_hsa040241.19090389
46Steroid biosynthesis_Homo sapiens_hsa001001.17395709
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.17305862
48Type II diabetes mellitus_Homo sapiens_hsa049301.13385633
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.11969024
50Selenocompound metabolism_Homo sapiens_hsa004501.09238180
51Vibrio cholerae infection_Homo sapiens_hsa051101.07927143
52ErbB signaling pathway_Homo sapiens_hsa040121.04710823
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.98808750
54cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98404002
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93640637
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93524570
57Estrogen signaling pathway_Homo sapiens_hsa049150.93380345
58Cardiac muscle contraction_Homo sapiens_hsa042600.92291643
59Primary bile acid biosynthesis_Homo sapiens_hsa001200.92185831
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.92136474
61Melanogenesis_Homo sapiens_hsa049160.91979313
62beta-Alanine metabolism_Homo sapiens_hsa004100.91624979
63Tryptophan metabolism_Homo sapiens_hsa003800.91522332
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.90595086
65Regulation of autophagy_Homo sapiens_hsa041400.90071607
66ABC transporters_Homo sapiens_hsa020100.89695142
67Pancreatic secretion_Homo sapiens_hsa049720.89505424
68Dorso-ventral axis formation_Homo sapiens_hsa043200.88462274
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.85942303
70RNA degradation_Homo sapiens_hsa030180.84264395
71Glioma_Homo sapiens_hsa052140.82816971
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82081776
73MAPK signaling pathway_Homo sapiens_hsa040100.81440112
74Huntingtons disease_Homo sapiens_hsa050160.80991181
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80914562
76Homologous recombination_Homo sapiens_hsa034400.80678778
77Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.78085991
78Choline metabolism in cancer_Homo sapiens_hsa052310.77675464
79Ras signaling pathway_Homo sapiens_hsa040140.75850132
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75025970
81Fatty acid biosynthesis_Homo sapiens_hsa000610.72943341
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71987070
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71454733
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71353362
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.69007014
86Thyroid hormone synthesis_Homo sapiens_hsa049180.66424319
87Inositol phosphate metabolism_Homo sapiens_hsa005620.65631332
88Dilated cardiomyopathy_Homo sapiens_hsa054140.64121374
89Alcoholism_Homo sapiens_hsa050340.63886470
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63828572
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.62343185
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62187134
93Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61713373
94Glycerolipid metabolism_Homo sapiens_hsa005610.60212047
95RNA polymerase_Homo sapiens_hsa030200.59638753
96Hippo signaling pathway_Homo sapiens_hsa043900.59293749
97Rap1 signaling pathway_Homo sapiens_hsa040150.59203133
98Peroxisome_Homo sapiens_hsa041460.58224729
99Histidine metabolism_Homo sapiens_hsa003400.57536456
100Alzheimers disease_Homo sapiens_hsa050100.57058901
101Oocyte meiosis_Homo sapiens_hsa041140.56559100
102Wnt signaling pathway_Homo sapiens_hsa043100.56084009
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56035731
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55661398
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55377803
106Ovarian steroidogenesis_Homo sapiens_hsa049130.54142445
107Chemical carcinogenesis_Homo sapiens_hsa052040.53172983
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52306725
109Rheumatoid arthritis_Homo sapiens_hsa053230.52039117
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.51979919
111Type I diabetes mellitus_Homo sapiens_hsa049400.51256185
112Ether lipid metabolism_Homo sapiens_hsa005650.50544899
113Retinol metabolism_Homo sapiens_hsa008300.49983458
114Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48854315
115Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48558444
116Oxidative phosphorylation_Homo sapiens_hsa001900.47449655
117African trypanosomiasis_Homo sapiens_hsa051430.47081974
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45937066
119Chemokine signaling pathway_Homo sapiens_hsa040620.45860930
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45384286
121Circadian rhythm_Homo sapiens_hsa047100.44929502
122Caffeine metabolism_Homo sapiens_hsa002320.44684019
123Renal cell carcinoma_Homo sapiens_hsa052110.44074983
124Basal cell carcinoma_Homo sapiens_hsa052170.43997533
125Sphingolipid metabolism_Homo sapiens_hsa006000.43464597
126Endocytosis_Homo sapiens_hsa041440.42715482
127Melanoma_Homo sapiens_hsa052180.41773101
128Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40927850
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38395175
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37718080
131VEGF signaling pathway_Homo sapiens_hsa043700.37696672
132Non-homologous end-joining_Homo sapiens_hsa034500.35879323
133Endometrial cancer_Homo sapiens_hsa052130.35084172
134Phagosome_Homo sapiens_hsa041450.35020814
135Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.30410572
136TGF-beta signaling pathway_Homo sapiens_hsa043500.29858008
137Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29498400
138Mineral absorption_Homo sapiens_hsa049780.29345607
139Parkinsons disease_Homo sapiens_hsa050120.28602666
140Hedgehog signaling pathway_Homo sapiens_hsa043400.27745029
141T cell receptor signaling pathway_Homo sapiens_hsa046600.27571413

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