Rank | Gene Set | Z-score |
---|---|---|
1 | chaperone-mediated protein transport (GO:0072321) | 6.08957244 |
2 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 6.06041361 |
3 | respiratory electron transport chain (GO:0022904) | 5.59559614 |
4 | electron transport chain (GO:0022900) | 5.47684013 |
5 | maturation of SSU-rRNA (GO:0030490) | 5.34464964 |
6 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.24830742 |
7 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.24830742 |
8 | NADH dehydrogenase complex assembly (GO:0010257) | 5.24830742 |
9 | protein complex biogenesis (GO:0070271) | 5.15509884 |
10 | DNA deamination (GO:0045006) | 4.95588594 |
11 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.94328423 |
12 | formation of translation preinitiation complex (GO:0001731) | 4.87085344 |
13 | protein neddylation (GO:0045116) | 4.77644792 |
14 | proteasome assembly (GO:0043248) | 4.64421939 |
15 | viral transcription (GO:0019083) | 4.63461938 |
16 | ribosomal small subunit assembly (GO:0000028) | 4.61021825 |
17 | translational termination (GO:0006415) | 4.60668536 |
18 | ribosomal large subunit biogenesis (GO:0042273) | 4.56395069 |
19 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.47496591 |
20 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.34829964 |
21 | ribosome assembly (GO:0042255) | 4.30030755 |
22 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.29947586 |
23 | translational initiation (GO:0006413) | 4.29884328 |
24 | ribosomal small subunit biogenesis (GO:0042274) | 4.29651268 |
25 | purine nucleobase biosynthetic process (GO:0009113) | 4.28691795 |
26 | cotranslational protein targeting to membrane (GO:0006613) | 4.24063282 |
27 | protein targeting to ER (GO:0045047) | 4.23844615 |
28 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.20848019 |
29 | translational elongation (GO:0006414) | 4.19466407 |
30 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.17782514 |
31 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.16205009 |
32 | nucleobase biosynthetic process (GO:0046112) | 4.15857934 |
33 | respiratory chain complex IV assembly (GO:0008535) | 4.08794906 |
34 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.07617289 |
35 | termination of RNA polymerase III transcription (GO:0006386) | 4.07617289 |
36 | negative regulation of ligase activity (GO:0051352) | 4.05298399 |
37 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.05298399 |
38 | ribosome biogenesis (GO:0042254) | 4.04963881 |
39 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.03420949 |
40 | protein localization to endoplasmic reticulum (GO:0070972) | 4.02880358 |
41 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.99967867 |
42 | protein-cofactor linkage (GO:0018065) | 3.98815866 |
43 | translation (GO:0006412) | 3.97200395 |
44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.85235342 |
45 | spliceosomal snRNP assembly (GO:0000387) | 3.84646148 |
46 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.82654149 |
47 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.82387992 |
48 | rRNA processing (GO:0006364) | 3.78479878 |
49 | DNA replication checkpoint (GO:0000076) | 3.73104128 |
50 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.72618690 |
51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.71933728 |
52 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.71746916 |
53 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.70688037 |
54 | cellular protein complex disassembly (GO:0043624) | 3.70327670 |
55 | ATP biosynthetic process (GO:0006754) | 3.68898474 |
56 | mitotic metaphase plate congression (GO:0007080) | 3.68668998 |
57 | viral life cycle (GO:0019058) | 3.68120355 |
58 | ATP synthesis coupled proton transport (GO:0015986) | 3.67215132 |
59 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.67215132 |
60 | cytochrome complex assembly (GO:0017004) | 3.66358888 |
61 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.65337927 |
62 | 7-methylguanosine mRNA capping (GO:0006370) | 3.64909138 |
63 | rRNA metabolic process (GO:0016072) | 3.64492034 |
64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.63912779 |
65 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.63912779 |
66 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.63789386 |
67 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.63789386 |
68 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.63789386 |
69 | positive regulation of ligase activity (GO:0051351) | 3.63637130 |
70 | hydrogen ion transmembrane transport (GO:1902600) | 3.63229248 |
71 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.62062289 |
72 | rRNA modification (GO:0000154) | 3.61072434 |
73 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.60914955 |
74 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.60914955 |
75 | RNA capping (GO:0036260) | 3.56037556 |
76 | 7-methylguanosine RNA capping (GO:0009452) | 3.56037556 |
77 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.55894534 |
78 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.55894534 |
79 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.55766675 |
80 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.55261584 |
81 | regulation of mitochondrial translation (GO:0070129) | 3.54666994 |
82 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.54291568 |
83 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.51965116 |
84 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.51098613 |
85 | DNA strand elongation (GO:0022616) | 3.50628353 |
86 | cullin deneddylation (GO:0010388) | 3.46161594 |
87 | DNA replication initiation (GO:0006270) | 3.45675312 |
88 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.45244058 |
89 | cellular component biogenesis (GO:0044085) | 3.45187718 |
90 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.43370122 |
91 | pseudouridine synthesis (GO:0001522) | 3.42992793 |
92 | mitochondrial transport (GO:0006839) | 3.41450839 |
93 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.39764943 |
94 | intracellular protein transmembrane import (GO:0044743) | 3.39309383 |
95 | protein deneddylation (GO:0000338) | 3.37252433 |
96 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.35965271 |
97 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.35921905 |
98 | spliceosomal complex assembly (GO:0000245) | 3.32613194 |
99 | oxidative phosphorylation (GO:0006119) | 3.32478873 |
100 | transcription from RNA polymerase I promoter (GO:0006360) | 3.29668876 |
101 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.28522377 |
102 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.27251390 |
103 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.24913273 |
104 | cell cycle G1/S phase transition (GO:0044843) | 3.24816550 |
105 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.24816550 |
106 | establishment of protein localization to mitochondrion (GO:0072655) | 3.24489837 |
107 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.24355084 |
108 | termination of RNA polymerase I transcription (GO:0006363) | 3.24338865 |
109 | proton transport (GO:0015992) | 3.23614210 |
110 | regulation of ligase activity (GO:0051340) | 3.22234479 |
111 | protein complex disassembly (GO:0043241) | 3.21632499 |
112 | inner mitochondrial membrane organization (GO:0007007) | 3.21346279 |
113 | protein targeting to mitochondrion (GO:0006626) | 3.19198533 |
114 | hydrogen transport (GO:0006818) | 3.17097998 |
115 | telomere maintenance via recombination (GO:0000722) | 3.15210085 |
116 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.14925060 |
117 | macromolecular complex disassembly (GO:0032984) | 3.13993239 |
118 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.13122140 |
119 | positive regulation of cell cycle arrest (GO:0071158) | 3.08624659 |
120 | protein localization to mitochondrion (GO:0070585) | 3.07914569 |
121 | protein targeting to membrane (GO:0006612) | 3.04489766 |
122 | peptidyl-histidine modification (GO:0018202) | 3.02998022 |
123 | CENP-A containing nucleosome assembly (GO:0034080) | 3.01497946 |
124 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.98833866 |
125 | establishment of integrated proviral latency (GO:0075713) | 2.98427248 |
126 | viral mRNA export from host cell nucleus (GO:0046784) | 2.98067316 |
127 | IMP biosynthetic process (GO:0006188) | 2.97461467 |
128 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.96403220 |
129 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.96403220 |
130 | chromatin remodeling at centromere (GO:0031055) | 2.95549044 |
131 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.94834103 |
132 | GTP biosynthetic process (GO:0006183) | 2.94732388 |
133 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.93302134 |
134 | rRNA methylation (GO:0031167) | 2.89769163 |
135 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.86837646 |
136 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.86837646 |
137 | regulation of cellular respiration (GO:0043457) | 2.83262694 |
138 | tRNA processing (GO:0008033) | 2.82851484 |
139 | organelle disassembly (GO:1903008) | 2.81471712 |
140 | regulation of hexokinase activity (GO:1903299) | 2.75677805 |
141 | regulation of glucokinase activity (GO:0033131) | 2.75677805 |
142 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.75406683 |
143 | mitochondrion morphogenesis (GO:0070584) | 2.75291973 |
144 | DNA damage response, detection of DNA damage (GO:0042769) | 2.74674846 |
145 | purine nucleotide salvage (GO:0032261) | 2.73910089 |
146 | intracellular protein transmembrane transport (GO:0065002) | 2.73044172 |
147 | histone exchange (GO:0043486) | 2.72179369 |
148 | protein transmembrane transport (GO:0071806) | 2.71587694 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.30532126 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.63278921 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.21051507 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.05126367 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.02139938 |
6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.65305094 |
7 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.57292821 |
8 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.56518057 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.43715019 |
10 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.12564425 |
11 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.09139545 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.99510861 |
13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.76096974 |
14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.74356997 |
15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.73324198 |
16 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.65731568 |
17 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.55305581 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.54166867 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.52246811 |
20 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 2.50091963 |
21 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.45345446 |
22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.37699648 |
23 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.34613186 |
24 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.34553848 |
25 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.33368969 |
26 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.22174805 |
27 | VDR_22108803_ChIP-Seq_LS180_Human | 2.22067663 |
28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.15177183 |
29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.12518700 |
30 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12282745 |
31 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.07243478 |
32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03548304 |
33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.03375895 |
34 | * PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96256410 |
35 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.95624074 |
36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.94665803 |
37 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.88058518 |
38 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.85771074 |
39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.82096164 |
40 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.80924937 |
41 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.77713753 |
42 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.77413484 |
43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.76219059 |
44 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75908328 |
45 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.70756397 |
46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70274644 |
47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.67512333 |
48 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.67230774 |
49 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63718869 |
50 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.62659509 |
51 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.62096500 |
52 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61896797 |
53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.60365029 |
54 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.59857684 |
55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.54502326 |
56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53416315 |
57 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.52116858 |
58 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.49853727 |
59 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.48140397 |
60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46490754 |
61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.45066282 |
62 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.43021776 |
63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.40479668 |
64 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40274960 |
65 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.35992076 |
66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.35735950 |
67 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.34892547 |
68 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33930058 |
69 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.31033667 |
70 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.23806699 |
71 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.23351945 |
72 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.21784317 |
73 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21766464 |
74 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.21555885 |
75 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.20481681 |
76 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.19196327 |
77 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.18662405 |
78 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.18382550 |
79 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.17348172 |
80 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15835539 |
81 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.14766233 |
82 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.12597350 |
83 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.11117342 |
84 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.10123577 |
85 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.09908650 |
86 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.09886360 |
87 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.09865405 |
88 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09165116 |
89 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07915338 |
90 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.07831216 |
91 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.07462784 |
92 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.07249872 |
93 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.05535018 |
94 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.05343439 |
95 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.04606580 |
96 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.04077819 |
97 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.01762720 |
98 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.01691014 |
99 | P300_19829295_ChIP-Seq_ESCs_Human | 1.01501735 |
100 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.00457011 |
101 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99595594 |
102 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99522050 |
103 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.99387673 |
104 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.99259397 |
105 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98203075 |
106 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.97533573 |
107 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.97150005 |
108 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.96842075 |
109 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96726808 |
110 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96726808 |
111 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.96715739 |
112 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.96211724 |
113 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.94064020 |
114 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.93305908 |
115 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.92994094 |
116 | MYC_22102868_ChIP-Seq_BL_Human | 0.92559963 |
117 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.91422069 |
118 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.91150539 |
119 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.90684525 |
120 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.89059113 |
121 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88714133 |
122 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.87432883 |
123 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.86082738 |
124 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85554723 |
125 | * TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.85465534 |
126 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.84881585 |
127 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84660267 |
128 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83549503 |
129 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.83469058 |
130 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.83122610 |
131 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.82614550 |
132 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82426363 |
133 | NCOR_22424771_ChIP-Seq_293T_Human | 0.81821304 |
134 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.81698659 |
135 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.80411340 |
136 | AR_20517297_ChIP-Seq_VCAP_Human | 0.79545431 |
137 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.79323066 |
138 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.79063355 |
139 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.78999661 |
140 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.78060666 |
141 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.77976999 |
142 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.77976999 |
143 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.77041465 |
144 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.76448486 |
145 | JUN_21703547_ChIP-Seq_K562_Human | 0.75733922 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 6.54568270 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.92182302 |
3 | MP0003111_abnormal_nucleus_morphology | 3.88391125 |
4 | MP0003077_abnormal_cell_cycle | 3.65265267 |
5 | MP0010094_abnormal_chromosome_stability | 3.58427272 |
6 | MP0008932_abnormal_embryonic_tissue | 3.05819152 |
7 | MP0008058_abnormal_DNA_repair | 2.72129860 |
8 | MP0003123_paternal_imprinting | 2.62786236 |
9 | MP0003718_maternal_effect | 2.62742611 |
10 | MP0008057_abnormal_DNA_replication | 2.37916724 |
11 | MP0001730_embryonic_growth_arrest | 2.32216345 |
12 | MP0008007_abnormal_cellular_replicative | 2.28739496 |
13 | MP0009046_muscle_twitch | 2.24488186 |
14 | MP0006072_abnormal_retinal_apoptosis | 2.20398974 |
15 | MP0000750_abnormal_muscle_regeneration | 2.15070560 |
16 | MP0006036_abnormal_mitochondrial_physio | 2.11190147 |
17 | MP0009333_abnormal_splenocyte_physiolog | 2.10409128 |
18 | MP0005084_abnormal_gallbladder_morpholo | 2.06292119 |
19 | MP0002102_abnormal_ear_morphology | 2.02349362 |
20 | MP0000350_abnormal_cell_proliferation | 2.01592597 |
21 | MP0003646_muscle_fatigue | 1.94542411 |
22 | MP0004142_abnormal_muscle_tone | 1.91450897 |
23 | MP0003011_delayed_dark_adaptation | 1.91059480 |
24 | MP0005646_abnormal_pituitary_gland | 1.87740236 |
25 | MP0003186_abnormal_redox_activity | 1.86866145 |
26 | MP0003786_premature_aging | 1.86169701 |
27 | MP0001984_abnormal_olfaction | 1.77215537 |
28 | MP0002736_abnormal_nociception_after | 1.76022749 |
29 | MP0006035_abnormal_mitochondrial_morpho | 1.69131013 |
30 | MP0001697_abnormal_embryo_size | 1.66215205 |
31 | MP0003221_abnormal_cardiomyocyte_apopto | 1.62876976 |
32 | MP0000358_abnormal_cell_content/ | 1.61998302 |
33 | MP0002080_prenatal_lethality | 1.59923610 |
34 | MP0001905_abnormal_dopamine_level | 1.59634488 |
35 | MP0003806_abnormal_nucleotide_metabolis | 1.58392697 |
36 | MP0001968_abnormal_touch/_nociception | 1.53022099 |
37 | MP0003880_abnormal_central_pattern | 1.50434141 |
38 | MP0002272_abnormal_nervous_system | 1.49742361 |
39 | MP0002638_abnormal_pupillary_reflex | 1.48903786 |
40 | MP0005551_abnormal_eye_electrophysiolog | 1.48797320 |
41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46509409 |
42 | MP0000313_abnormal_cell_death | 1.45691785 |
43 | MP0009379_abnormal_foot_pigmentation | 1.45570418 |
44 | MP0005380_embryogenesis_phenotype | 1.45143539 |
45 | MP0001672_abnormal_embryogenesis/_devel | 1.45143539 |
46 | MP0004084_abnormal_cardiac_muscle | 1.44152645 |
47 | MP0009745_abnormal_behavioral_response | 1.40241384 |
48 | MP0001764_abnormal_homeostasis | 1.39267031 |
49 | MP0000490_abnormal_crypts_of | 1.38116447 |
50 | MP0008872_abnormal_physiological_respon | 1.37865914 |
51 | MP0005670_abnormal_white_adipose | 1.37705944 |
52 | MP0005253_abnormal_eye_physiology | 1.36032982 |
53 | MP0005332_abnormal_amino_acid | 1.35083684 |
54 | MP0002396_abnormal_hematopoietic_system | 1.34978561 |
55 | MP0003195_calcinosis | 1.32042637 |
56 | MP0003136_yellow_coat_color | 1.31594833 |
57 | MP0009697_abnormal_copulation | 1.30669643 |
58 | MP0003984_embryonic_growth_retardation | 1.30018564 |
59 | MP0004147_increased_porphyrin_level | 1.29970411 |
60 | MP0008260_abnormal_autophagy | 1.29447239 |
61 | MP0003315_abnormal_perineum_morphology | 1.28057298 |
62 | MP0010307_abnormal_tumor_latency | 1.27631373 |
63 | MP0005379_endocrine/exocrine_gland_phen | 1.26729292 |
64 | MP0010386_abnormal_urinary_bladder | 1.26309275 |
65 | MP0002088_abnormal_embryonic_growth/wei | 1.25444888 |
66 | MP0010352_gastrointestinal_tract_polyps | 1.22968095 |
67 | MP0006276_abnormal_autonomic_nervous | 1.21679972 |
68 | MP0008789_abnormal_olfactory_epithelium | 1.21318411 |
69 | MP0001485_abnormal_pinna_reflex | 1.20482953 |
70 | MP0004145_abnormal_muscle_electrophysio | 1.20148185 |
71 | MP0002876_abnormal_thyroid_physiology | 1.19386812 |
72 | MP0002019_abnormal_tumor_incidence | 1.18525275 |
73 | MP0002234_abnormal_pharynx_morphology | 1.18073564 |
74 | MP0005187_abnormal_penis_morphology | 1.17999538 |
75 | MP0003787_abnormal_imprinting | 1.15298531 |
76 | MP0002085_abnormal_embryonic_tissue | 1.14387149 |
77 | MP0001529_abnormal_vocalization | 1.13229775 |
78 | MP0002163_abnormal_gland_morphology | 1.12331255 |
79 | MP0001188_hyperpigmentation | 1.12281261 |
80 | MP0005645_abnormal_hypothalamus_physiol | 1.09686711 |
81 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09684914 |
82 | MP0001542_abnormal_bone_strength | 1.06229457 |
83 | MP0000858_altered_metastatic_potential | 1.05378188 |
84 | MP0003121_genomic_imprinting | 1.02822296 |
85 | MP0003950_abnormal_plasma_membrane | 1.01710108 |
86 | MP0000049_abnormal_middle_ear | 1.01556925 |
87 | MP0008995_early_reproductive_senescence | 1.01270410 |
88 | MP0008877_abnormal_DNA_methylation | 1.01250561 |
89 | MP0000631_abnormal_neuroendocrine_gland | 0.98402787 |
90 | MP0002084_abnormal_developmental_patter | 0.98083667 |
91 | MP0001853_heart_inflammation | 0.97290002 |
92 | MP0004808_abnormal_hematopoietic_stem | 0.95008404 |
93 | MP0002277_abnormal_respiratory_mucosa | 0.94909562 |
94 | MP0005330_cardiomyopathy | 0.94198434 |
95 | MP0000747_muscle_weakness | 0.92706091 |
96 | MP0002269_muscular_atrophy | 0.92521917 |
97 | MP0000703_abnormal_thymus_morphology | 0.92469976 |
98 | MP0002064_seizures | 0.92353449 |
99 | MP0002106_abnormal_muscle_physiology | 0.91614465 |
100 | MP0002086_abnormal_extraembryonic_tissu | 0.91448442 |
101 | MP0000749_muscle_degeneration | 0.91001899 |
102 | MP0001727_abnormal_embryo_implantation | 0.89526693 |
103 | MP0009250_abnormal_appendicular_skeleto | 0.89269160 |
104 | MP0004036_abnormal_muscle_relaxation | 0.89257496 |
105 | MP0000013_abnormal_adipose_tissue | 0.88631954 |
106 | MP0004742_abnormal_vestibular_system | 0.87918825 |
107 | MP0005384_cellular_phenotype | 0.87635940 |
108 | MP0002722_abnormal_immune_system | 0.87309614 |
109 | MP0005389_reproductive_system_phenotype | 0.85779969 |
110 | MP0002398_abnormal_bone_marrow | 0.85162761 |
111 | MP0002210_abnormal_sex_determination | 0.83146411 |
112 | MP0002693_abnormal_pancreas_physiology | 0.82224343 |
113 | MP0003137_abnormal_impulse_conducting | 0.82003294 |
114 | MP0004885_abnormal_endolymph | 0.81306929 |
115 | MP0005671_abnormal_response_to | 0.81233589 |
116 | MP0006292_abnormal_olfactory_placode | 0.80346434 |
117 | MP0002090_abnormal_vision | 0.79792395 |
118 | MP0004197_abnormal_fetal_growth/weight/ | 0.79748494 |
119 | MP0004043_abnormal_pH_regulation | 0.79437956 |
120 | MP0002160_abnormal_reproductive_system | 0.79253564 |
121 | MP0010030_abnormal_orbit_morphology | 0.78822049 |
122 | MP0002067_abnormal_sensory_capabilities | 0.78154447 |
123 | MP0001145_abnormal_male_reproductive | 0.76645997 |
124 | MP0002132_abnormal_respiratory_system | 0.76420659 |
125 | MP0000689_abnormal_spleen_morphology | 0.76407340 |
126 | MP0000372_irregular_coat_pigmentation | 0.76127977 |
127 | MP0003763_abnormal_thymus_physiology | 0.75445834 |
128 | MP0002095_abnormal_skin_pigmentation | 0.74670460 |
129 | MP0002429_abnormal_blood_cell | 0.74527319 |
130 | MP0001440_abnormal_grooming_behavior | 0.74381450 |
131 | MP0009840_abnormal_foam_cell | 0.74098508 |
132 | MP0005195_abnormal_posterior_eye | 0.73430437 |
133 | MP0005621_abnormal_cell_physiology | 0.73058711 |
134 | MP0005386_behavior/neurological_phenoty | 0.71905722 |
135 | MP0004924_abnormal_behavior | 0.71905722 |
136 | MP0001293_anophthalmia | 0.71052787 |
137 | MP0009785_altered_susceptibility_to | 0.70987962 |
138 | MP0006054_spinal_hemorrhage | 0.70476720 |
139 | MP0005636_abnormal_mineral_homeostasis | 0.70401300 |
140 | MP0004215_abnormal_myocardial_fiber | 0.69652360 |
141 | MP0001944_abnormal_pancreas_morphology | 0.68573745 |
142 | MP0002837_dystrophic_cardiac_calcinosis | 0.68143456 |
143 | MP0003119_abnormal_digestive_system | 0.67692831 |
144 | MP0008775_abnormal_heart_ventricle | 0.67655062 |
145 | MP0000759_abnormal_skeletal_muscle | 0.67418811 |
146 | MP0002572_abnormal_emotion/affect_behav | 0.65836464 |
147 | MP0002735_abnormal_chemical_nociception | 0.64737422 |
148 | MP0001919_abnormal_reproductive_system | 0.64230651 |
149 | MP0005620_abnormal_muscle_contractility | 0.63696450 |
150 | MP0000716_abnormal_immune_system | 0.62843057 |
151 | MP0005410_abnormal_fertilization | 0.62571401 |
152 | MP0005395_other_phenotype | 0.62055428 |
153 | MP0002938_white_spotting | 0.61040068 |
154 | MP0005408_hypopigmentation | 0.60060854 |
155 | MP0000428_abnormal_craniofacial_morphol | 0.59415028 |
156 | MP0002877_abnormal_melanocyte_morpholog | 0.59215296 |
157 | MP0004233_abnormal_muscle_weight | 0.58948026 |
158 | MP0005266_abnormal_metabolism | 0.57587738 |
159 | MP0005369_muscle_phenotype | 0.57338531 |
160 | MP0003436_decreased_susceptibility_to | 0.57303937 |
161 | MP0001545_abnormal_hematopoietic_system | 0.56967747 |
162 | MP0005397_hematopoietic_system_phenotyp | 0.56967747 |
163 | MP0000653_abnormal_sex_gland | 0.55964511 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.85597566 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 4.47352881 |
3 | Birth length less than 3rd percentile (HP:0003561) | 4.33362176 |
4 | Acute necrotizing encephalopathy (HP:0006965) | 4.27032791 |
5 | Reticulocytopenia (HP:0001896) | 4.16253743 |
6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.99378537 |
7 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.96940150 |
8 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.96940150 |
9 | Renal Fanconi syndrome (HP:0001994) | 3.93918325 |
10 | Mitochondrial inheritance (HP:0001427) | 3.71249752 |
11 | Multiple enchondromatosis (HP:0005701) | 3.65890532 |
12 | Cerebral hypomyelination (HP:0006808) | 3.64231868 |
13 | Carpal bone hypoplasia (HP:0001498) | 3.58286489 |
14 | Rough bone trabeculation (HP:0100670) | 3.57099578 |
15 | Abnormality of the anterior horn cell (HP:0006802) | 3.54053829 |
16 | Degeneration of anterior horn cells (HP:0002398) | 3.54053829 |
17 | Hepatocellular necrosis (HP:0001404) | 3.52642239 |
18 | Breast hypoplasia (HP:0003187) | 3.50558804 |
19 | Macrocytic anemia (HP:0001972) | 3.46545724 |
20 | Increased CSF lactate (HP:0002490) | 3.43192218 |
21 | Hepatic necrosis (HP:0002605) | 3.38389360 |
22 | Progressive macrocephaly (HP:0004481) | 3.29982226 |
23 | Acute encephalopathy (HP:0006846) | 3.25883535 |
24 | Oral leukoplakia (HP:0002745) | 3.24833882 |
25 | Pallor (HP:0000980) | 3.20530560 |
26 | Progressive muscle weakness (HP:0003323) | 3.12199913 |
27 | Abnormality of alanine metabolism (HP:0010916) | 3.08841388 |
28 | Hyperalaninemia (HP:0003348) | 3.08841388 |
29 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.08841388 |
30 | Increased serum lactate (HP:0002151) | 2.99070897 |
31 | Methylmalonic acidemia (HP:0002912) | 2.97142782 |
32 | Microretrognathia (HP:0000308) | 2.93520271 |
33 | Abnormality of glycolysis (HP:0004366) | 2.89881512 |
34 | Increased serum pyruvate (HP:0003542) | 2.89881512 |
35 | Increased hepatocellular lipid droplets (HP:0006565) | 2.87428261 |
36 | Abnormality of midbrain morphology (HP:0002418) | 2.83180151 |
37 | Molar tooth sign on MRI (HP:0002419) | 2.83180151 |
38 | 3-Methylglutaconic aciduria (HP:0003535) | 2.82458600 |
39 | Leukodystrophy (HP:0002415) | 2.80829625 |
40 | Aplastic anemia (HP:0001915) | 2.75708098 |
41 | Trismus (HP:0000211) | 2.73305591 |
42 | Secondary amenorrhea (HP:0000869) | 2.72144590 |
43 | Exercise intolerance (HP:0003546) | 2.66071144 |
44 | Glossoptosis (HP:0000162) | 2.65054754 |
45 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63760817 |
46 | Optic disc pallor (HP:0000543) | 2.62284209 |
47 | Methylmalonic aciduria (HP:0012120) | 2.61210074 |
48 | Lactic acidosis (HP:0003128) | 2.60906273 |
49 | Abnormal trabecular bone morphology (HP:0100671) | 2.60154327 |
50 | Poor head control (HP:0002421) | 2.59397306 |
51 | Respiratory failure (HP:0002878) | 2.58976121 |
52 | Lipid accumulation in hepatocytes (HP:0006561) | 2.57779855 |
53 | Abnormality of renal resorption (HP:0011038) | 2.54983669 |
54 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.54208536 |
55 | Patellar aplasia (HP:0006443) | 2.54142868 |
56 | Pelvic girdle muscle weakness (HP:0003749) | 2.51491828 |
57 | Shoulder girdle muscle weakness (HP:0003547) | 2.50619139 |
58 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.45509916 |
59 | Abnormality of the umbilical cord (HP:0010881) | 2.45367933 |
60 | Emotional lability (HP:0000712) | 2.44112565 |
61 | Premature ovarian failure (HP:0008209) | 2.43394754 |
62 | Lethargy (HP:0001254) | 2.41923570 |
63 | CNS demyelination (HP:0007305) | 2.41776780 |
64 | Glycosuria (HP:0003076) | 2.41580960 |
65 | Abnormality of urine glucose concentration (HP:0011016) | 2.41580960 |
66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.40968655 |
67 | Pancreatic fibrosis (HP:0100732) | 2.37047627 |
68 | Premature graying of hair (HP:0002216) | 2.34755189 |
69 | Generalized aminoaciduria (HP:0002909) | 2.34377488 |
70 | Pancreatic cysts (HP:0001737) | 2.33984619 |
71 | Postnatal microcephaly (HP:0005484) | 2.32770442 |
72 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.32757592 |
73 | Congenital, generalized hypertrichosis (HP:0004540) | 2.32043938 |
74 | Calcaneovalgus deformity (HP:0001848) | 2.31461132 |
75 | Irregular epiphyses (HP:0010582) | 2.27056873 |
76 | Colon cancer (HP:0003003) | 2.26719396 |
77 | Personality changes (HP:0000751) | 2.26677439 |
78 | Abnormality of serum amino acid levels (HP:0003112) | 2.26437626 |
79 | Deformed tarsal bones (HP:0008119) | 2.24323056 |
80 | Unsteady gait (HP:0002317) | 2.24300386 |
81 | Cleft eyelid (HP:0000625) | 2.23307372 |
82 | Large for gestational age (HP:0001520) | 2.22877769 |
83 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.21870396 |
84 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.21870396 |
85 | Cerebral edema (HP:0002181) | 2.21214398 |
86 | 11 pairs of ribs (HP:0000878) | 2.21144941 |
87 | Respiratory difficulties (HP:0002880) | 2.17574239 |
88 | Nemaline bodies (HP:0003798) | 2.16711408 |
89 | Neoplasm of the pancreas (HP:0002894) | 2.16403835 |
90 | Abnormality of methionine metabolism (HP:0010901) | 2.15862116 |
91 | Delusions (HP:0000746) | 2.12763764 |
92 | Exertional dyspnea (HP:0002875) | 2.12650720 |
93 | Increased intramyocellular lipid droplets (HP:0012240) | 2.12283869 |
94 | Type I transferrin isoform profile (HP:0003642) | 2.10714720 |
95 | True hermaphroditism (HP:0010459) | 2.09166824 |
96 | CNS hypomyelination (HP:0003429) | 2.08309043 |
97 | Hypoplasia of the pons (HP:0012110) | 2.05595865 |
98 | Selective tooth agenesis (HP:0001592) | 2.05341072 |
99 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.02889847 |
100 | X-linked dominant inheritance (HP:0001423) | 2.02830661 |
101 | Cellular immunodeficiency (HP:0005374) | 2.02650349 |
102 | Muscle fiber inclusion bodies (HP:0100299) | 2.01277861 |
103 | Sparse eyelashes (HP:0000653) | 2.00904034 |
104 | Distal arthrogryposis (HP:0005684) | 2.00203862 |
105 | Horseshoe kidney (HP:0000085) | 1.98578435 |
106 | Hypoglycemic coma (HP:0001325) | 1.98507623 |
107 | Microvesicular hepatic steatosis (HP:0001414) | 1.98361906 |
108 | Renal cortical cysts (HP:0000803) | 1.96986904 |
109 | Hyperphosphaturia (HP:0003109) | 1.94368886 |
110 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.92585534 |
111 | Absent thumb (HP:0009777) | 1.92314048 |
112 | Areflexia of lower limbs (HP:0002522) | 1.91855569 |
113 | Patent foramen ovale (HP:0001655) | 1.91627730 |
114 | Rimmed vacuoles (HP:0003805) | 1.90736776 |
115 | Slender long bone (HP:0003100) | 1.90104210 |
116 | Difficulty climbing stairs (HP:0003551) | 1.89655728 |
117 | Megaloblastic anemia (HP:0001889) | 1.89276606 |
118 | Medial flaring of the eyebrow (HP:0010747) | 1.88952061 |
119 | Abnormality of the calcaneus (HP:0008364) | 1.88773438 |
120 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.88377965 |
121 | Muscle fiber atrophy (HP:0100295) | 1.85433247 |
122 | Abnormality of the renal cortex (HP:0011035) | 1.85214087 |
123 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.84938074 |
124 | Hyperglycinemia (HP:0002154) | 1.84115199 |
125 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.81150233 |
126 | Rhabdomyolysis (HP:0003201) | 1.79938612 |
127 | Increased muscle lipid content (HP:0009058) | 1.79440308 |
128 | Abnormality of the pons (HP:0007361) | 1.79404116 |
129 | Dicarboxylic aciduria (HP:0003215) | 1.79206240 |
130 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.79206240 |
131 | Abnormality of the labia minora (HP:0012880) | 1.78656331 |
132 | Nephronophthisis (HP:0000090) | 1.77821317 |
133 | Myokymia (HP:0002411) | 1.76649122 |
134 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.74868139 |
135 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.74868139 |
136 | Abnormal protein glycosylation (HP:0012346) | 1.74868139 |
137 | Abnormal glycosylation (HP:0012345) | 1.74868139 |
138 | Abnormality of vitamin B metabolism (HP:0004340) | 1.72921143 |
139 | Poor suck (HP:0002033) | 1.68485312 |
140 | Reduced antithrombin III activity (HP:0001976) | 1.68285325 |
141 | Ketoacidosis (HP:0001993) | 1.66175617 |
142 | Hypomagnesemia (HP:0002917) | 1.65757458 |
143 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.64677852 |
144 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.64655524 |
145 | Testicular atrophy (HP:0000029) | 1.63721647 |
146 | Sensory axonal neuropathy (HP:0003390) | 1.63602062 |
147 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.63422082 |
148 | Blindness (HP:0000618) | 1.59216310 |
149 | Homocystinuria (HP:0002156) | 1.59161006 |
150 | Abnormality of homocysteine metabolism (HP:0010919) | 1.59161006 |
151 | Progressive microcephaly (HP:0000253) | 1.59065728 |
152 | Abnormality of magnesium homeostasis (HP:0004921) | 1.55829707 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.18549041 |
2 | NME2 | 4.52113020 |
3 | WEE1 | 4.18038418 |
4 | EIF2AK1 | 3.44058569 |
5 | STK16 | 3.03841167 |
6 | TSSK6 | 2.41350766 |
7 | TLK1 | 2.32257643 |
8 | PLK4 | 2.31645475 |
9 | TESK2 | 2.31364786 |
10 | EIF2AK3 | 2.25808902 |
11 | NME1 | 2.24819476 |
12 | CDC7 | 2.21519931 |
13 | ACVR1B | 2.20938202 |
14 | VRK2 | 2.20644170 |
15 | MAP3K12 | 2.15255908 |
16 | SRPK1 | 2.14713426 |
17 | BMPR1B | 2.07256364 |
18 | BRSK2 | 2.03440126 |
19 | NEK1 | 1.96711219 |
20 | WNK3 | 1.87282188 |
21 | DYRK3 | 1.84832360 |
22 | RPS6KA4 | 1.84591261 |
23 | NEK2 | 1.80975918 |
24 | PIM2 | 1.73726508 |
25 | PHKG1 | 1.72564174 |
26 | PHKG2 | 1.72564174 |
27 | FRK | 1.71798627 |
28 | VRK1 | 1.66355174 |
29 | TESK1 | 1.65072455 |
30 | SCYL2 | 1.60633361 |
31 | PLK1 | 1.57604267 |
32 | ADRBK2 | 1.51151568 |
33 | CAMKK2 | 1.50453246 |
34 | LIMK1 | 1.48364280 |
35 | PBK | 1.47488183 |
36 | KDR | 1.47227242 |
37 | PASK | 1.46179135 |
38 | ARAF | 1.45804628 |
39 | MAP4K2 | 1.40869413 |
40 | MYLK | 1.40426341 |
41 | PLK3 | 1.39944099 |
42 | BRAF | 1.37182290 |
43 | MAP3K4 | 1.36299263 |
44 | NUAK1 | 1.35022393 |
45 | GRK1 | 1.33889856 |
46 | AURKB | 1.33219800 |
47 | EPHA2 | 1.31391336 |
48 | TTK | 1.30056953 |
49 | AURKA | 1.26503992 |
50 | MAP2K7 | 1.25470693 |
51 | ZAK | 1.19589421 |
52 | BRSK1 | 1.16249856 |
53 | WNK4 | 1.13303842 |
54 | CASK | 1.10645520 |
55 | TNIK | 1.09848561 |
56 | INSRR | 1.04148989 |
57 | MKNK1 | 1.00341834 |
58 | MAP3K8 | 0.99970657 |
59 | RPS6KB2 | 0.99628627 |
60 | PNCK | 0.99480115 |
61 | OXSR1 | 0.97756672 |
62 | CSNK1G3 | 0.97561867 |
63 | PAK3 | 0.97434151 |
64 | TRIM28 | 0.97070817 |
65 | CSNK1G2 | 0.95948150 |
66 | BCKDK | 0.95680127 |
67 | IRAK3 | 0.95039348 |
68 | LRRK2 | 0.94306110 |
69 | STK38L | 0.93697702 |
70 | ILK | 0.92757800 |
71 | ERBB3 | 0.92724559 |
72 | PRKCG | 0.91067055 |
73 | DYRK2 | 0.89963249 |
74 | CDK7 | 0.89885221 |
75 | MAP3K11 | 0.89524837 |
76 | STK39 | 0.87615824 |
77 | CSNK1G1 | 0.86333681 |
78 | ABL2 | 0.84824774 |
79 | PLK2 | 0.83152168 |
80 | CHEK2 | 0.77463879 |
81 | ATR | 0.76525852 |
82 | PAK1 | 0.75713659 |
83 | RPS6KA5 | 0.72044888 |
84 | TAOK3 | 0.70861049 |
85 | PAK4 | 0.69602501 |
86 | CSNK2A1 | 0.68968214 |
87 | MKNK2 | 0.68641639 |
88 | CSNK2A2 | 0.66310274 |
89 | PDK4 | 0.65172814 |
90 | PDK3 | 0.65172814 |
91 | ZAP70 | 0.65067608 |
92 | MINK1 | 0.64150362 |
93 | BLK | 0.63269907 |
94 | TIE1 | 0.62934223 |
95 | CCNB1 | 0.62882096 |
96 | PRKCI | 0.62682844 |
97 | CHEK1 | 0.61309135 |
98 | ADRBK1 | 0.60311510 |
99 | RAF1 | 0.58598104 |
100 | MAPK13 | 0.58541423 |
101 | CAMK1 | 0.57280768 |
102 | MARK1 | 0.56722827 |
103 | PKN1 | 0.56133987 |
104 | DMPK | 0.54858399 |
105 | PIM1 | 0.54008840 |
106 | PRKCE | 0.53428534 |
107 | MAPKAPK3 | 0.53297511 |
108 | CDK4 | 0.53041112 |
109 | MARK3 | 0.52858875 |
110 | LATS2 | 0.52328825 |
111 | CAMK2D | 0.51413348 |
112 | OBSCN | 0.50712934 |
113 | CAMK2A | 0.50171715 |
114 | EIF2AK2 | 0.49369053 |
115 | GRK7 | 0.48111636 |
116 | CSNK1A1L | 0.47967320 |
117 | TAF1 | 0.47816420 |
118 | TAOK2 | 0.46117712 |
119 | CDK3 | 0.45815195 |
120 | PRKACA | 0.44617383 |
121 | CAMK2G | 0.44427141 |
122 | STK3 | 0.44145460 |
123 | CSNK1A1 | 0.43652079 |
124 | TTN | 0.42449668 |
125 | MAP2K2 | 0.41876228 |
126 | CDK2 | 0.41138290 |
127 | MAP2K3 | 0.38491783 |
128 | PINK1 | 0.38122978 |
129 | MAP3K5 | 0.38063177 |
130 | MUSK | 0.36518753 |
131 | PIK3CG | 0.35695484 |
132 | CDK8 | 0.35381910 |
133 | PDK2 | 0.34187689 |
134 | FLT3 | 0.34042496 |
135 | MAP3K3 | 0.32268664 |
136 | JAK3 | 0.30087718 |
137 | IRAK4 | 0.29651263 |
138 | ATM | 0.27939420 |
139 | STK24 | 0.27808122 |
140 | CDK19 | 0.27217302 |
141 | STK4 | 0.26544856 |
142 | MAP4K1 | 0.26042153 |
143 | TGFBR1 | 0.26028962 |
144 | CSNK1E | 0.25535895 |
145 | CDK1 | 0.20664789 |
146 | MST4 | 0.19919136 |
147 | ALK | 0.19636752 |
148 | DAPK3 | 0.19283618 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 5.01675772 |
2 | Ribosome_Homo sapiens_hsa03010 | 4.49329936 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 4.12093314 |
4 | DNA replication_Homo sapiens_hsa03030 | 3.69040907 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.53964039 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 3.07577870 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.01317170 |
8 | RNA transport_Homo sapiens_hsa03013 | 2.88514815 |
9 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.73773567 |
10 | Protein export_Homo sapiens_hsa03060 | 2.58178240 |
11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.47511342 |
12 | Parkinsons disease_Homo sapiens_hsa05012 | 2.33339275 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.33190747 |
14 | Homologous recombination_Homo sapiens_hsa03440 | 2.15600589 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.05493811 |
16 | Base excision repair_Homo sapiens_hsa03410 | 2.00609327 |
17 | Cell cycle_Homo sapiens_hsa04110 | 1.95252077 |
18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.91732736 |
19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.58653533 |
20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.56400624 |
21 | RNA degradation_Homo sapiens_hsa03018 | 1.55237769 |
22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.52137759 |
23 | Purine metabolism_Homo sapiens_hsa00230 | 1.51207532 |
24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.47292225 |
25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.45912382 |
26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.45411186 |
27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.45263457 |
28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.44608038 |
29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39103619 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.38563216 |
31 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.36143068 |
32 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.32613908 |
33 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.31106685 |
34 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.27337609 |
35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.24758532 |
36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15236407 |
37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09806526 |
38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.09124865 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.03105105 |
40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.00298560 |
41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98808379 |
42 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.98738899 |
43 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.98487385 |
44 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.95323876 |
45 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.93813622 |
46 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.92220741 |
47 | Peroxisome_Homo sapiens_hsa04146 | 0.88326275 |
48 | Legionellosis_Homo sapiens_hsa05134 | 0.87925629 |
49 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.87672761 |
50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.81984708 |
51 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79981262 |
52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77897727 |
53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77817406 |
54 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.77790032 |
55 | Phototransduction_Homo sapiens_hsa04744 | 0.76067661 |
56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73779956 |
57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.72357184 |
58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.71605223 |
59 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.69927041 |
60 | Carbon metabolism_Homo sapiens_hsa01200 | 0.68655403 |
61 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.67997135 |
62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.67483122 |
63 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.66408415 |
64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.64363726 |
65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.63471441 |
66 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.60990187 |
67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59565943 |
68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.59127720 |
69 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.56916297 |
70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.55583947 |
71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54633118 |
72 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54515689 |
73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.53989463 |
74 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53621870 |
75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51819263 |
76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.49301087 |
77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.47128247 |
78 | Galactose metabolism_Homo sapiens_hsa00052 | 0.46924031 |
79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46307753 |
80 | Shigellosis_Homo sapiens_hsa05131 | 0.45866725 |
81 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.44462614 |
82 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.44083538 |
83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.43672798 |
84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42046166 |
85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41995855 |
86 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.40287881 |
87 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.39443369 |
88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.38692134 |
89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38689721 |
90 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.38291146 |
91 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37672818 |
92 | Mineral absorption_Homo sapiens_hsa04978 | 0.37369606 |
93 | Thyroid cancer_Homo sapiens_hsa05216 | 0.37090599 |
94 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.36797691 |
95 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.36735350 |
96 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.36706479 |
97 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36444369 |
98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.36145493 |
99 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.36092601 |
100 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.35952504 |
101 | HTLV-I infection_Homo sapiens_hsa05166 | 0.35087846 |
102 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.35001280 |
103 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34609047 |
104 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.33470377 |
105 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33451140 |
106 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.33360951 |
107 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.32102871 |
108 | Apoptosis_Homo sapiens_hsa04210 | 0.31332248 |
109 | Morphine addiction_Homo sapiens_hsa05032 | 0.30172407 |
110 | Alcoholism_Homo sapiens_hsa05034 | 0.28663966 |
111 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.28108535 |
112 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.27917238 |
113 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.27099215 |
114 | Measles_Homo sapiens_hsa05162 | 0.26886293 |
115 | Allograft rejection_Homo sapiens_hsa05330 | 0.26574613 |
116 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.25850107 |
117 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.24412034 |
118 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.24017539 |
119 | Insulin secretion_Homo sapiens_hsa04911 | 0.23569439 |
120 | Olfactory transduction_Homo sapiens_hsa04740 | 0.23276238 |
121 | Taste transduction_Homo sapiens_hsa04742 | 0.21779888 |
122 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.20918043 |
123 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.20816174 |
124 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.18984158 |
125 | Asthma_Homo sapiens_hsa05310 | 0.18744415 |
126 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.18393617 |
127 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.17995858 |
128 | Hepatitis B_Homo sapiens_hsa05161 | 0.17239240 |
129 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.16758633 |
130 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.14614430 |
131 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.13701810 |
132 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.12443865 |
133 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.11640462 |
134 | Viral myocarditis_Homo sapiens_hsa05416 | 0.10413768 |
135 | Phagosome_Homo sapiens_hsa04145 | 0.09621381 |
136 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.09173895 |
137 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.08566236 |
138 | Influenza A_Homo sapiens_hsa05164 | 0.08046577 |
139 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.06640736 |
140 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.04767731 |
141 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.04344265 |
142 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.02426306 |
143 | Lysosome_Homo sapiens_hsa04142 | 0.02358233 |
144 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.02030854 |
145 | Bladder cancer_Homo sapiens_hsa05219 | 0.01246465 |