Rank | Gene Set | Z-score |
---|---|---|
1 | cardiac myofibril assembly (GO:0055003) | 7.71741785 |
2 | sarcomere organization (GO:0045214) | 7.47546146 |
3 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.89377878 |
4 | * regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 6.87079909 |
5 | myofibril assembly (GO:0030239) | 6.56537212 |
6 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 6.35200991 |
7 | * regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 6.29201965 |
8 | * regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.27898102 |
9 | * cardiac muscle contraction (GO:0060048) | 5.94163555 |
10 | regulation of relaxation of muscle (GO:1901077) | 5.77603975 |
11 | regulation of actin filament-based movement (GO:1903115) | 5.75337200 |
12 | cardiac muscle cell development (GO:0055013) | 5.39013728 |
13 | * cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 5.36090106 |
14 | regulation of cell communication by electrical coupling (GO:0010649) | 5.17687128 |
15 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 5.15978277 |
16 | * positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.14325580 |
17 | cardiac cell development (GO:0055006) | 5.03702669 |
18 | regulation of sarcomere organization (GO:0060297) | 5.00493187 |
19 | adult heart development (GO:0007512) | 5.00390199 |
20 | * cell communication involved in cardiac conduction (GO:0086065) | 4.99414188 |
21 | cardiac chamber formation (GO:0003207) | 4.97436098 |
22 | regulation of membrane repolarization (GO:0060306) | 4.93739041 |
23 | tricarboxylic acid cycle (GO:0006099) | 4.92398306 |
24 | plasma membrane repair (GO:0001778) | 4.90732620 |
25 | actin-myosin filament sliding (GO:0033275) | 4.86529331 |
26 | muscle filament sliding (GO:0030049) | 4.86529331 |
27 | * regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.84618416 |
28 | actomyosin structure organization (GO:0031032) | 4.83702774 |
29 | * ventricular cardiac muscle cell action potential (GO:0086005) | 4.73911094 |
30 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.67745809 |
31 | * cardiac muscle tissue morphogenesis (GO:0055008) | 4.67209225 |
32 | * cell communication by electrical coupling (GO:0010644) | 4.66854450 |
33 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.65993850 |
34 | regulation of the force of heart contraction (GO:0002026) | 4.63798625 |
35 | * cardiac muscle hypertrophy (GO:0003300) | 4.61489151 |
36 | regulation of cardiac muscle cell contraction (GO:0086004) | 4.59775840 |
37 | relaxation of cardiac muscle (GO:0055119) | 4.53084331 |
38 | * regulation of striated muscle contraction (GO:0006942) | 4.48178399 |
39 | * ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 4.38813509 |
40 | * striated muscle contraction (GO:0006941) | 4.36393196 |
41 | * striated muscle hypertrophy (GO:0014897) | 4.35428422 |
42 | regulation of skeletal muscle contraction (GO:0014819) | 4.33985564 |
43 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 4.32288982 |
44 | cardiac ventricle formation (GO:0003211) | 4.22293683 |
45 | carnitine shuttle (GO:0006853) | 4.15493651 |
46 | cardiac conduction (GO:0061337) | 4.12835716 |
47 | * regulation of cardiac muscle contraction (GO:0055117) | 4.12762888 |
48 | heart trabecula formation (GO:0060347) | 4.11868555 |
49 | * muscle tissue morphogenesis (GO:0060415) | 4.10859373 |
50 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.09695892 |
51 | positive regulation of action potential (GO:0045760) | 4.07618857 |
52 | actin-mediated cell contraction (GO:0070252) | 4.07022296 |
53 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.02696830 |
54 | * regulation of ATPase activity (GO:0043462) | 3.90391806 |
55 | * regulation of ATP catabolic process (GO:1903289) | 3.90391806 |
56 | regulation of heart rate by cardiac conduction (GO:0086091) | 3.88153687 |
57 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.85627373 |
58 | * regulation of heart rate (GO:0002027) | 3.78823225 |
59 | negative regulation of potassium ion transport (GO:0043267) | 3.77744659 |
60 | regulation of cofactor metabolic process (GO:0051193) | 3.76660727 |
61 | regulation of coenzyme metabolic process (GO:0051196) | 3.76660727 |
62 | * muscle hypertrophy (GO:0014896) | 3.75958525 |
63 | * cardiac muscle cell action potential (GO:0086001) | 3.74397108 |
64 | negative regulation of protein localization to cell surface (GO:2000009) | 3.72916456 |
65 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.72297220 |
66 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.71764671 |
67 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.66802267 |
68 | muscle hypertrophy in response to stress (GO:0003299) | 3.66802267 |
69 | cardiac muscle adaptation (GO:0014887) | 3.66802267 |
70 | positive regulation of sodium ion transport (GO:0010765) | 3.64055759 |
71 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.63225158 |
72 | * regulation of heart contraction (GO:0008016) | 3.61986950 |
73 | * cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.61119604 |
74 | * regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.59401804 |
75 | * regulation of calcium ion transmembrane transport (GO:1903169) | 3.59401804 |
76 | * positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.58997337 |
77 | response to inactivity (GO:0014854) | 3.57004532 |
78 | NADH metabolic process (GO:0006734) | 3.55079619 |
79 | fatty acid transmembrane transport (GO:1902001) | 3.54539601 |
80 | heart process (GO:0003015) | 3.52618665 |
81 | heart contraction (GO:0060047) | 3.52618665 |
82 | * regulation of muscle contraction (GO:0006937) | 3.42164308 |
83 | regulation of cardioblast differentiation (GO:0051890) | 3.40571836 |
84 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.40341668 |
85 | atrial septum morphogenesis (GO:0060413) | 3.38509880 |
86 | activation of protein kinase A activity (GO:0034199) | 3.31286780 |
87 | cardiac muscle tissue development (GO:0048738) | 3.30731020 |
88 | * muscle contraction (GO:0006936) | 3.28171724 |
89 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.28102833 |
90 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.28102833 |
91 | striated muscle adaptation (GO:0014888) | 3.28062117 |
92 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.27700568 |
93 | ventricular cardiac muscle cell development (GO:0055015) | 3.25975794 |
94 | * regulation of muscle system process (GO:0090257) | 3.25935957 |
95 | positive regulation of cardiac muscle tissue growth (GO:0055023) | 3.22554860 |
96 | potassium ion import (GO:0010107) | 3.21513772 |
97 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 3.20027061 |
98 | regulation of potassium ion transmembrane transport (GO:1901379) | 3.17637230 |
99 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.16934709 |
100 | * sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.16675727 |
101 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 3.13333866 |
102 | actin filament-based movement (GO:0030048) | 3.12734077 |
103 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.11646696 |
104 | * positive regulation of cation channel activity (GO:2001259) | 3.11152334 |
105 | * muscle system process (GO:0003012) | 3.11064245 |
106 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.08403783 |
107 | potassium ion export (GO:0071435) | 3.08197734 |
108 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 3.07284257 |
109 | desmosome organization (GO:0002934) | 3.07216463 |
110 | relaxation of muscle (GO:0090075) | 3.06551086 |
111 | carnitine transmembrane transport (GO:1902603) | 3.04219770 |
112 | relaxation of smooth muscle (GO:0044557) | 3.04045439 |
113 | striated muscle cell development (GO:0055002) | 3.03767744 |
114 | membrane repolarization during action potential (GO:0086011) | 3.03524578 |
115 | regulation of synapse structural plasticity (GO:0051823) | 3.03350083 |
116 | * regulation of cation channel activity (GO:2001257) | 3.02610897 |
117 | regulation of sulfur metabolic process (GO:0042762) | 3.02356076 |
118 | sodium ion export (GO:0071436) | 3.01397010 |
119 | oxygen transport (GO:0015671) | 2.99869755 |
120 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.99328522 |
121 | membrane repolarization (GO:0086009) | 2.99305859 |
122 | multicellular organismal signaling (GO:0035637) | 2.96616931 |
123 | positive regulation of potassium ion transport (GO:0043268) | 2.96317121 |
124 | membrane depolarization during action potential (GO:0086010) | 2.96013653 |
125 | * detection of calcium ion (GO:0005513) | 2.93768896 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.55563470 |
2 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 3.48805743 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.67816664 |
4 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.67176087 |
5 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.51929457 |
6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.49038577 |
7 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.35123924 |
8 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.27975505 |
9 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.27975505 |
10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.20425711 |
11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.17306458 |
12 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.17017352 |
13 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.15240095 |
14 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.12521937 |
15 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.12521937 |
16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.03911724 |
17 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.03170827 |
18 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.02445564 |
19 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.99473095 |
20 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.99060386 |
21 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.90249847 |
22 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.81656021 |
23 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.78437320 |
24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.78146693 |
25 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.75927809 |
26 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.74723753 |
27 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.70873395 |
28 | * MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.66574209 |
29 | GATA1_22025678_ChIP-Seq_K562_Human | 1.65021607 |
30 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.63910144 |
31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.59262291 |
32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.57022647 |
33 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.55807676 |
34 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.55370859 |
35 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55135704 |
36 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.53998202 |
37 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.52082207 |
38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.50525756 |
39 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.49228110 |
40 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.49208141 |
41 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.46013463 |
42 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.39548259 |
43 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38676276 |
44 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.38478510 |
45 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.37733323 |
46 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34386271 |
47 | TP53_16413492_ChIP-PET_HCT116_Human | 1.33893567 |
48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.32928437 |
49 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.32652714 |
50 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.32196593 |
51 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.31184991 |
52 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.30010187 |
53 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.30005720 |
54 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.29442017 |
55 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29438360 |
56 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.28424143 |
57 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.27407063 |
58 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.27169936 |
59 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.27047328 |
60 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.26111333 |
61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.24249532 |
62 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.22335109 |
63 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.21420133 |
64 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.21169870 |
65 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21159962 |
66 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.20443616 |
67 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.19287599 |
68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.18766404 |
69 | * AR_19668381_ChIP-Seq_PC3_Human | 1.17216233 |
70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.17067352 |
71 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.15886652 |
72 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.15739207 |
73 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13847700 |
74 | * TAF15_26573619_Chip-Seq_HEK293_Human | 1.11768021 |
75 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.11373047 |
76 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.10749022 |
77 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.08730848 |
78 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.08730848 |
79 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.08234551 |
80 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.07941215 |
81 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07865156 |
82 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.07810430 |
83 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.06156994 |
84 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.05773491 |
85 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.05218170 |
86 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.05165335 |
87 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.04325298 |
88 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.04062694 |
89 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.03482887 |
90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.03138504 |
91 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.02722065 |
92 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.02100185 |
93 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.01531924 |
94 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.01367934 |
95 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.01218377 |
96 | * BCAT_22108803_ChIP-Seq_LS180_Human | 1.01216693 |
97 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.00862020 |
98 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98662481 |
99 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.98391390 |
100 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97811076 |
101 | * P300_19829295_ChIP-Seq_ESCs_Human | 0.97543311 |
102 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.97367164 |
103 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.96606635 |
104 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96147267 |
105 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.94704542 |
106 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 0.94596578 |
107 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94469699 |
108 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.94049823 |
109 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.93444639 |
110 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.93251507 |
111 | * MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.93203576 |
112 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.92478573 |
113 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.92087877 |
114 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.91483673 |
115 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.91202411 |
116 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.90791672 |
117 | GF1_26923725_Chip-Seq_HPCs_Mouse | 0.90570490 |
118 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.90453320 |
119 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.90312920 |
120 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.89917330 |
121 | KDM2B_26808549_Chip-Seq_K562_Human | 0.88818522 |
122 | AR_25329375_ChIP-Seq_VCAP_Human | 0.88247243 |
123 | * TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.87474592 |
124 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.85708562 |
125 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.83391328 |
126 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.83180744 |
127 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.81977755 |
128 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80899766 |
129 | * TBL1_22424771_ChIP-Seq_293T_Human | 0.79987669 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 6.45463915 |
2 | MP0004084_abnormal_cardiac_muscle | 5.56402844 |
3 | * MP0004215_abnormal_myocardial_fiber | 4.88212539 |
4 | MP0000751_myopathy | 4.84330652 |
5 | MP0003646_muscle_fatigue | 4.77534528 |
6 | MP0004036_abnormal_muscle_relaxation | 3.95207109 |
7 | * MP0005330_cardiomyopathy | 3.43420308 |
8 | MP0000749_muscle_degeneration | 3.38451288 |
9 | MP0003137_abnormal_impulse_conducting | 3.17744468 |
10 | MP0008775_abnormal_heart_ventricle | 3.01259236 |
11 | * MP0002972_abnormal_cardiac_muscle | 2.96104587 |
12 | MP0004087_abnormal_muscle_fiber | 2.74462421 |
13 | * MP0005620_abnormal_muscle_contractility | 2.51859741 |
14 | MP0004859_abnormal_synaptic_plasticity | 2.46685556 |
15 | MP0001544_abnormal_cardiovascular_syste | 2.42357715 |
16 | MP0005385_cardiovascular_system_phenoty | 2.42357715 |
17 | * MP0004085_abnormal_heartbeat | 2.40713559 |
18 | MP0004145_abnormal_muscle_electrophysio | 2.33666017 |
19 | * MP0010630_abnormal_cardiac_muscle | 2.31091762 |
20 | MP0006138_congestive_heart_failure | 2.29545225 |
21 | * MP0004484_altered_response_of | 2.29003129 |
22 | MP0004130_abnormal_muscle_cell | 2.26606340 |
23 | MP0000750_abnormal_muscle_regeneration | 2.21797820 |
24 | * MP0002106_abnormal_muscle_physiology | 2.07439913 |
25 | MP0003828_pulmonary_edema | 2.05486556 |
26 | MP0002269_muscular_atrophy | 2.02664182 |
27 | MP0002127_abnormal_cardiovascular_syste | 1.79562286 |
28 | MP0004233_abnormal_muscle_weight | 1.71368555 |
29 | * MP0005369_muscle_phenotype | 1.68764430 |
30 | MP0000747_muscle_weakness | 1.68653803 |
31 | MP0003221_abnormal_cardiomyocyte_apopto | 1.66865144 |
32 | MP0000759_abnormal_skeletal_muscle | 1.60737739 |
33 | MP0003880_abnormal_central_pattern | 1.58597628 |
34 | MP0003950_abnormal_plasma_membrane | 1.48549345 |
35 | MP0003635_abnormal_synaptic_transmissio | 1.46994378 |
36 | MP0008004_abnormal_stomach_pH | 1.27089086 |
37 | * MP0004510_myositis | 1.26348649 |
38 | MP0009046_muscle_twitch | 1.26333294 |
39 | MP0006036_abnormal_mitochondrial_physio | 1.17028223 |
40 | MP0002332_abnormal_exercise_endurance | 1.16044059 |
41 | * MP0009745_abnormal_behavioral_response | 1.12496804 |
42 | MP0002909_abnormal_adrenal_gland | 1.11550668 |
43 | MP0002822_catalepsy | 1.09238026 |
44 | MP0002063_abnormal_learning/memory/cond | 1.07595813 |
45 | MP0004270_analgesia | 1.04748712 |
46 | * MP0002064_seizures | 1.02990657 |
47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.02182401 |
48 | MP0005623_abnormal_meninges_morphology | 1.01762696 |
49 | MP0002234_abnormal_pharynx_morphology | 1.01732951 |
50 | MP0010368_abnormal_lymphatic_system | 1.01290333 |
51 | MP0002735_abnormal_chemical_nociception | 1.00940003 |
52 | MP0004924_abnormal_behavior | 0.99717369 |
53 | MP0005386_behavior/neurological_phenoty | 0.99717369 |
54 | * MP0000266_abnormal_heart_morphology | 0.98823078 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 0.98522132 |
56 | MP0001661_extended_life_span | 0.97626703 |
57 | MP0005670_abnormal_white_adipose | 0.97394597 |
58 | MP0005666_abnormal_adipose_tissue | 0.96363987 |
59 | MP0001984_abnormal_olfaction | 0.96287055 |
60 | * MP0002272_abnormal_nervous_system | 0.96234436 |
61 | MP0006035_abnormal_mitochondrial_morpho | 0.93691781 |
62 | MP0008569_lethality_at_weaning | 0.90775269 |
63 | MP0002572_abnormal_emotion/affect_behav | 0.88333921 |
64 | MP0001486_abnormal_startle_reflex | 0.84433252 |
65 | MP0001440_abnormal_grooming_behavior | 0.82981844 |
66 | MP0000230_abnormal_systemic_arterial | 0.79808426 |
67 | * MP0005165_increased_susceptibility_to | 0.79033427 |
68 | MP0003045_fibrosis | 0.77429471 |
69 | MP0002067_abnormal_sensory_capabilities | 0.76573353 |
70 | MP0003279_aneurysm | 0.75119024 |
71 | MP0001968_abnormal_touch/_nociception | 0.74550958 |
72 | MP0004043_abnormal_pH_regulation | 0.71014272 |
73 | MP0002108_abnormal_muscle_morphology | 0.69204708 |
74 | MP0002128_abnormal_blood_circulation | 0.65537898 |
75 | MP0005375_adipose_tissue_phenotype | 0.65260232 |
76 | MP0002734_abnormal_mechanical_nocicepti | 0.64955813 |
77 | MP0005187_abnormal_penis_morphology | 0.64062632 |
78 | MP0003633_abnormal_nervous_system | 0.59681846 |
79 | MP0002638_abnormal_pupillary_reflex | 0.59107264 |
80 | MP0001970_abnormal_pain_threshold | 0.58386608 |
81 | MP0004858_abnormal_nervous_system | 0.56595468 |
82 | MP0000767_abnormal_smooth_muscle | 0.56448255 |
83 | MP0001501_abnormal_sleep_pattern | 0.56265888 |
84 | MP0008961_abnormal_basal_metabolism | 0.55703363 |
85 | MP0004272_abnormal_basement_membrane | 0.54958907 |
86 | MP0005423_abnormal_somatic_nervous | 0.54469692 |
87 | MP0005535_abnormal_body_temperature | 0.54435163 |
88 | MP0003329_amyloid_beta_deposits | 0.52388391 |
89 | MP0002736_abnormal_nociception_after | 0.52143177 |
90 | MP0005266_abnormal_metabolism | 0.51666751 |
91 | MP0000013_abnormal_adipose_tissue | 0.51210862 |
92 | MP0008874_decreased_physiological_sensi | 0.51204280 |
93 | MP0002066_abnormal_motor_capabilities/c | 0.50916966 |
94 | MP0004185_abnormal_adipocyte_glucose | 0.48988498 |
95 | MP0005595_abnormal_vascular_smooth | 0.47539040 |
96 | MP0001529_abnormal_vocalization | 0.47110942 |
97 | MP0004142_abnormal_muscle_tone | 0.46485308 |
98 | MP0005409_darkened_coat_color | 0.46357505 |
99 | MP0009384_cardiac_valve_regurgitation | 0.46296117 |
100 | MP0003879_abnormal_hair_cell | 0.45012788 |
101 | MP0003566_abnormal_cell_adhesion | 0.43936863 |
102 | MP0004147_increased_porphyrin_level | 0.43657719 |
103 | MP0002184_abnormal_innervation | 0.43634537 |
104 | MP0000003_abnormal_adipose_tissue | 0.43066688 |
105 | MP0000462_abnormal_digestive_system | 0.42884620 |
106 | MP0001784_abnormal_fluid_regulation | 0.42540893 |
107 | MP0004811_abnormal_neuron_physiology | 0.41694938 |
108 | MP0002078_abnormal_glucose_homeostasis | 0.41231781 |
109 | MP0001879_abnormal_lymphatic_vessel | 0.41149155 |
110 | MP0003631_nervous_system_phenotype | 0.40697743 |
111 | MP0002295_abnormal_pulmonary_circulatio | 0.40365415 |
112 | * MP0000343_altered_response_to | 0.39915134 |
113 | MP0000579_abnormal_nail_morphology | 0.39720884 |
114 | MP0005503_abnormal_tendon_morphology | 0.36885344 |
115 | * MP0002925_abnormal_cardiovascular_devel | 0.36250729 |
116 | MP0001299_abnormal_eye_distance/ | 0.36216261 |
117 | MP0002102_abnormal_ear_morphology | 0.35476774 |
118 | MP0003690_abnormal_glial_cell | 0.34130874 |
119 | MP0003634_abnormal_glial_cell | 0.32774529 |
120 | MP0002090_abnormal_vision | 0.32378405 |
121 | MP0001614_abnormal_blood_vessel | 0.30242102 |
122 | MP0005388_respiratory_system_phenotype | 0.29918138 |
123 | MP0002133_abnormal_respiratory_system | 0.29918138 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Sudden death (HP:0001699) | 8.47756118 |
2 | * Atrial fibrillation (HP:0005110) | 6.57578654 |
3 | * Primary atrial arrhythmia (HP:0001692) | 6.18181028 |
4 | * Ventricular tachycardia (HP:0004756) | 6.10490808 |
5 | Calf muscle hypertrophy (HP:0008981) | 6.08705236 |
6 | * Supraventricular tachycardia (HP:0004755) | 5.93909326 |
7 | * Supraventricular arrhythmia (HP:0005115) | 5.80763989 |
8 | * Syncope (HP:0001279) | 5.55800604 |
9 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.47507823 |
10 | Abnormality of the calf musculature (HP:0001430) | 5.29877086 |
11 | Lipoatrophy (HP:0100578) | 5.27483251 |
12 | Prolonged QT interval (HP:0001657) | 5.23518969 |
13 | Bundle branch block (HP:0011710) | 5.23479216 |
14 | Muscle fiber splitting (HP:0003555) | 4.95014058 |
15 | Exercise-induced myalgia (HP:0003738) | 4.84458317 |
16 | Exercise-induced muscle cramps (HP:0003710) | 4.74786470 |
17 | Ventricular fibrillation (HP:0001663) | 4.68848988 |
18 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.46651316 |
19 | Subaortic stenosis (HP:0001682) | 4.46651316 |
20 | Hyporeflexia of lower limbs (HP:0002600) | 4.37643119 |
21 | Dilated cardiomyopathy (HP:0001644) | 4.36307616 |
22 | * Ventricular arrhythmia (HP:0004308) | 4.26834823 |
23 | Palpitations (HP:0001962) | 4.23068071 |
24 | Heart block (HP:0012722) | 4.22656533 |
25 | Atrioventricular block (HP:0001678) | 4.03682524 |
26 | Myoglobinuria (HP:0002913) | 4.02113348 |
27 | Abnormal EKG (HP:0003115) | 3.99072661 |
28 | Abnormal atrioventricular conduction (HP:0005150) | 3.93330096 |
29 | EMG: myopathic abnormalities (HP:0003458) | 3.80041425 |
30 | * Right ventricular cardiomyopathy (HP:0011663) | 3.57984365 |
31 | Asymmetric septal hypertrophy (HP:0001670) | 3.36937908 |
32 | Left ventricular hypertrophy (HP:0001712) | 3.30418836 |
33 | Myotonia (HP:0002486) | 3.14084141 |
34 | Dysmetric saccades (HP:0000641) | 3.08612209 |
35 | Increased connective tissue (HP:0009025) | 3.00019181 |
36 | Difficulty running (HP:0009046) | 2.89383833 |
37 | Focal motor seizures (HP:0011153) | 2.68661057 |
38 | Rhabdomyolysis (HP:0003201) | 2.64047728 |
39 | Palmoplantar keratoderma (HP:0000982) | 2.61892129 |
40 | Difficulty climbing stairs (HP:0003551) | 2.47128452 |
41 | Ketoacidosis (HP:0001993) | 2.43409689 |
42 | Steppage gait (HP:0003376) | 2.42699365 |
43 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.40753244 |
44 | Pheochromocytoma (HP:0002666) | 2.39582534 |
45 | Testicular atrophy (HP:0000029) | 2.33044007 |
46 | Acute necrotizing encephalopathy (HP:0006965) | 2.32378593 |
47 | Central scotoma (HP:0000603) | 2.27642465 |
48 | Hepatic necrosis (HP:0002605) | 2.21941708 |
49 | Increased variability in muscle fiber diameter (HP:0003557) | 2.17262863 |
50 | Ragged-red muscle fibers (HP:0003200) | 2.15576577 |
51 | * Sudden cardiac death (HP:0001645) | 2.12093109 |
52 | Type 1 muscle fiber predominance (HP:0003803) | 2.11837309 |
53 | Abnormality of the foot musculature (HP:0001436) | 2.11161756 |
54 | Hypoglycemic coma (HP:0001325) | 2.08502508 |
55 | Neuroendocrine neoplasm (HP:0100634) | 2.08453587 |
56 | Bradycardia (HP:0001662) | 2.06757765 |
57 | Scapular winging (HP:0003691) | 2.00371159 |
58 | Progressive macrocephaly (HP:0004481) | 2.00039939 |
59 | Hypoplastic ischia (HP:0003175) | 1.99444670 |
60 | Congestive heart failure (HP:0001635) | 1.99357495 |
61 | Resting tremor (HP:0002322) | 1.98863142 |
62 | Foot dorsiflexor weakness (HP:0009027) | 1.98564516 |
63 | Abnormality of the tricuspid valve (HP:0001702) | 1.97293258 |
64 | Distal lower limb amyotrophy (HP:0008944) | 1.97005856 |
65 | Lower limb amyotrophy (HP:0007210) | 1.96113761 |
66 | Toxemia of pregnancy (HP:0100603) | 1.95987380 |
67 | Hepatocellular necrosis (HP:0001404) | 1.95922060 |
68 | Muscular dystrophy (HP:0003560) | 1.95779325 |
69 | Double outlet right ventricle (HP:0001719) | 1.95767097 |
70 | Congenital malformation of the right heart (HP:0011723) | 1.95767097 |
71 | Distal lower limb muscle weakness (HP:0009053) | 1.95164278 |
72 | Myokymia (HP:0002411) | 1.94696808 |
73 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93744776 |
74 | Abnormality of alanine metabolism (HP:0010916) | 1.93744776 |
75 | Hyperalaninemia (HP:0003348) | 1.93744776 |
76 | Focal seizures (HP:0007359) | 1.93465062 |
77 | Neck muscle weakness (HP:0000467) | 1.92446165 |
78 | Limb-girdle muscle atrophy (HP:0003797) | 1.92094545 |
79 | Areflexia of lower limbs (HP:0002522) | 1.91554202 |
80 | Frequent falls (HP:0002359) | 1.90843416 |
81 | Generalized muscle weakness (HP:0003324) | 1.89863837 |
82 | Acute encephalopathy (HP:0006846) | 1.88652481 |
83 | Skin nodule (HP:0200036) | 1.87778230 |
84 | Hamartoma of the eye (HP:0010568) | 1.87217287 |
85 | EMG: neuropathic changes (HP:0003445) | 1.85356732 |
86 | Mitochondrial inheritance (HP:0001427) | 1.82737571 |
87 | Broad metatarsal (HP:0001783) | 1.81226941 |
88 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.80291016 |
89 | Hypoplastic heart (HP:0001961) | 1.80111758 |
90 | Dysdiadochokinesis (HP:0002075) | 1.79677503 |
91 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.79452247 |
92 | Rimmed vacuoles (HP:0003805) | 1.78932122 |
93 | Neoplasm of the adrenal gland (HP:0100631) | 1.78847333 |
94 | Hypoplastic left heart (HP:0004383) | 1.78276339 |
95 | Conjunctival hamartoma (HP:0100780) | 1.77274770 |
96 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.76380231 |
97 | Muscle stiffness (HP:0003552) | 1.76293052 |
98 | Large for gestational age (HP:0001520) | 1.76131783 |
99 | Athetosis (HP:0002305) | 1.75949217 |
100 | Increased CSF lactate (HP:0002490) | 1.75749186 |
101 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.73918639 |
102 | Abnormality of the ischium (HP:0003174) | 1.73657973 |
103 | Increased muscle lipid content (HP:0009058) | 1.73386210 |
104 | Dicarboxylic aciduria (HP:0003215) | 1.73345272 |
105 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.73345272 |
106 | Abnormality of the salivary glands (HP:0010286) | 1.73156224 |
107 | Visual hallucinations (HP:0002367) | 1.72990671 |
108 | Diaphragmatic weakness (HP:0009113) | 1.72017490 |
109 | Cerebral edema (HP:0002181) | 1.71382167 |
110 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.70679437 |
111 | Gowers sign (HP:0003391) | 1.69222392 |
112 | Hip contracture (HP:0003273) | 1.66480766 |
113 | Patent foramen ovale (HP:0001655) | 1.60778435 |
114 | Skin pits (HP:0100276) | 1.59370862 |
115 | Abnormality of the endocardium (HP:0004306) | 1.58661203 |
116 | Childhood onset (HP:0011463) | 1.57308220 |
117 | Increased serum pyruvate (HP:0003542) | 1.56471092 |
118 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.54350184 |
119 | Abnormality of glycolysis (HP:0004366) | 1.53648044 |
120 | Limb hypertonia (HP:0002509) | 1.52638343 |
121 | Preauricular pit (HP:0004467) | 1.49926106 |
122 | Periauricular skin pits (HP:0100277) | 1.49926106 |
123 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.46089404 |
124 | Limited hip movement (HP:0008800) | 1.36033036 |
125 | Bicuspid aortic valve (HP:0001647) | 1.32959137 |
126 | Febrile seizures (HP:0002373) | 1.31626496 |
127 | Slow progression (HP:0003677) | 1.31288674 |
128 | Lymphangioma (HP:0100764) | 1.30793384 |
129 | Proximal amyotrophy (HP:0007126) | 1.30161712 |
130 | Atonic seizures (HP:0010819) | 1.29611315 |
131 | Abnormal ventriculo-arterial connection (HP:0011563) | 1.28749943 |
132 | Abnormal connection of the cardiac segments (HP:0011545) | 1.28749943 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 4.63550370 |
2 | LMTK2 | 3.80547501 |
3 | TTN | 3.72967842 |
4 | PHKG2 | 3.44990693 |
5 | PHKG1 | 3.44990693 |
6 | MYLK | 3.21250613 |
7 | DMPK | 3.15672378 |
8 | PDK4 | 2.84311032 |
9 | PDK3 | 2.84311032 |
10 | PKN2 | 2.29550818 |
11 | MUSK | 2.17879235 |
12 | EPHA4 | 2.06985378 |
13 | NTRK3 | 2.06221671 |
14 | PIK3CA | 1.98281813 |
15 | STK24 | 1.84857189 |
16 | PINK1 | 1.83687537 |
17 | NEK1 | 1.79342784 |
18 | GRK7 | 1.72645264 |
19 | NEK9 | 1.72018361 |
20 | PAK3 | 1.65209848 |
21 | MAP3K4 | 1.62422678 |
22 | TIE1 | 1.61616065 |
23 | PDK2 | 1.57409158 |
24 | STK38 | 1.51687900 |
25 | INSRR | 1.47401668 |
26 | TRIB3 | 1.43881998 |
27 | CDC42BPA | 1.35830602 |
28 | ZAK | 1.34642535 |
29 | FLT3 | 1.28035890 |
30 | PRKD1 | 1.25995888 |
31 | * CAMK2D | 1.25072080 |
32 | MAP3K7 | 1.22994194 |
33 | PAK6 | 1.21762412 |
34 | CAMK1 | 1.21489430 |
35 | WNK1 | 1.14597205 |
36 | WNK4 | 1.12084378 |
37 | BCKDK | 1.11386687 |
38 | PRKD3 | 1.09232770 |
39 | CAMK4 | 1.08456962 |
40 | * CAMK2A | 1.02547626 |
41 | PTK2B | 1.01819382 |
42 | CASK | 0.99491882 |
43 | MAP3K6 | 0.99132488 |
44 | RIPK1 | 0.97301099 |
45 | ROCK1 | 0.97122142 |
46 | ILK | 0.96760643 |
47 | MAPKAPK3 | 0.94535047 |
48 | MAP3K9 | 0.94053541 |
49 | EPHA3 | 0.90326809 |
50 | MAP2K4 | 0.87791350 |
51 | DAPK2 | 0.87059018 |
52 | MAPK12 | 0.86517150 |
53 | PKN1 | 0.84289858 |
54 | DAPK3 | 0.83643035 |
55 | MAP2K7 | 0.82583510 |
56 | PRKAA1 | 0.80850839 |
57 | MAP3K5 | 0.78883203 |
58 | MINK1 | 0.78336735 |
59 | PRPF4B | 0.76009757 |
60 | PRKCE | 0.73501937 |
61 | TGFBR2 | 0.72971100 |
62 | PRKCH | 0.72740084 |
63 | KSR2 | 0.72520230 |
64 | LIMK1 | 0.72202181 |
65 | ROCK2 | 0.71843639 |
66 | MARK1 | 0.71248786 |
67 | PRKAA2 | 0.70978428 |
68 | AKT3 | 0.70592584 |
69 | CAMKK1 | 0.70072826 |
70 | TNIK | 0.62246492 |
71 | SGK3 | 0.60950277 |
72 | PRKACB | 0.60006839 |
73 | PDGFRA | 0.59262121 |
74 | PDK1 | 0.59002742 |
75 | CAMK2B | 0.58971809 |
76 | PDPK1 | 0.58548380 |
77 | MAPK7 | 0.58090429 |
78 | CDK5 | 0.57882827 |
79 | MAPK4 | 0.57780538 |
80 | LATS1 | 0.57415855 |
81 | SGK2 | 0.57012631 |
82 | SGK1 | 0.56986771 |
83 | STK39 | 0.55768412 |
84 | FRK | 0.53960361 |
85 | CAMK2G | 0.51994666 |
86 | NTRK2 | 0.51946908 |
87 | * PRKACA | 0.51532545 |
88 | STK38L | 0.51521508 |
89 | RET | 0.51373921 |
90 | STK11 | 0.51355584 |
91 | CAMK1G | 0.48764887 |
92 | UHMK1 | 0.47457481 |
93 | SGK494 | 0.46010425 |
94 | SGK223 | 0.46010425 |
95 | STK4 | 0.44679167 |
96 | MAPK10 | 0.44022441 |
97 | ITK | 0.43136848 |
98 | MARK2 | 0.42003080 |
99 | GRK5 | 0.41862919 |
100 | FER | 0.40177800 |
101 | KSR1 | 0.40015882 |
102 | * PRKACG | 0.39955076 |
103 | MAP2K1 | 0.38677285 |
104 | TRPM7 | 0.37591785 |
105 | CAMKK2 | 0.37361253 |
106 | MAPK13 | 0.37106474 |
107 | LATS2 | 0.36660684 |
108 | * RPS6KA3 | 0.36492956 |
109 | PLK2 | 0.36247069 |
110 | * PRKG1 | 0.35793724 |
111 | RPS6KA6 | 0.33955688 |
112 | NTRK1 | 0.32761602 |
113 | PRKCG | 0.32454569 |
114 | ICK | 0.30796575 |
115 | RAF1 | 0.29460317 |
116 | DAPK1 | 0.29246949 |
117 | RPS6KC1 | 0.28817588 |
118 | RPS6KL1 | 0.28817588 |
119 | RPS6KA1 | 0.27617226 |
120 | AKT2 | 0.25493361 |
121 | TAOK1 | 0.24469486 |
122 | PLK4 | 0.23951772 |
123 | PRKCB | 0.19016876 |
124 | PDGFRB | 0.18630121 |
125 | FGFR1 | 0.18386590 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 4.35412216 |
2 | * Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.82490759 |
3 | * Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.57680737 |
4 | * Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.24441072 |
5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.01861951 |
6 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.52678166 |
7 | * Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 2.29987303 |
8 | * Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.26087311 |
9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.07775841 |
10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.07114501 |
11 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.06059289 |
12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.81607249 |
13 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.77573492 |
14 | * Circadian entrainment_Homo sapiens_hsa04713 | 1.74340633 |
15 | Nicotine addiction_Homo sapiens_hsa05033 | 1.70185237 |
16 | Carbon metabolism_Homo sapiens_hsa01200 | 1.53562153 |
17 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.53003749 |
18 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.51687086 |
19 | * Calcium signaling pathway_Homo sapiens_hsa04020 | 1.51622734 |
20 | Long-term potentiation_Homo sapiens_hsa04720 | 1.51197496 |
21 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.44424259 |
22 | Olfactory transduction_Homo sapiens_hsa04740 | 1.44279863 |
23 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.42622811 |
24 | Morphine addiction_Homo sapiens_hsa05032 | 1.41119214 |
25 | Renin secretion_Homo sapiens_hsa04924 | 1.38087681 |
26 | * Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.36642977 |
27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.36123184 |
28 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.35677732 |
29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.33755786 |
30 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.32985246 |
31 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.31179750 |
32 | * Insulin secretion_Homo sapiens_hsa04911 | 1.30965746 |
33 | Salivary secretion_Homo sapiens_hsa04970 | 1.29502435 |
34 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.25438444 |
35 | Taste transduction_Homo sapiens_hsa04742 | 1.24940415 |
36 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.22598147 |
37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.21929878 |
38 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19832017 |
39 | Viral myocarditis_Homo sapiens_hsa05416 | 1.16060465 |
40 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.13976611 |
41 | * cAMP signaling pathway_Homo sapiens_hsa04024 | 1.12497521 |
42 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.07945321 |
43 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.07102089 |
44 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.05937890 |
45 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.05029749 |
46 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.96295319 |
47 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.94071942 |
48 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.93059360 |
49 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.88345845 |
50 | Insulin resistance_Homo sapiens_hsa04931 | 0.81360018 |
51 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.80721371 |
52 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.80310155 |
53 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.79252920 |
54 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.79177905 |
55 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.76749082 |
56 | Gap junction_Homo sapiens_hsa04540 | 0.76332246 |
57 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.76329903 |
58 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.75094792 |
59 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.72165687 |
60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71558441 |
61 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.69395615 |
62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68148589 |
63 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.63507004 |
64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.62219510 |
65 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.61929536 |
66 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61430430 |
67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61061868 |
68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59727873 |
69 | Long-term depression_Homo sapiens_hsa04730 | 0.59473925 |
70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.59186746 |
71 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.59080139 |
72 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.57081937 |
73 | Circadian rhythm_Homo sapiens_hsa04710 | 0.56759837 |
74 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.56429968 |
75 | Lysine degradation_Homo sapiens_hsa00310 | 0.56156374 |
76 | Focal adhesion_Homo sapiens_hsa04510 | 0.55445971 |
77 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.54793658 |
78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.54713157 |
79 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.54037079 |
80 | Platelet activation_Homo sapiens_hsa04611 | 0.53939849 |
81 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.53573624 |
82 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52712659 |
83 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.52492496 |
84 | Amoebiasis_Homo sapiens_hsa05146 | 0.52116578 |
85 | Mineral absorption_Homo sapiens_hsa04978 | 0.51035966 |
86 | Cocaine addiction_Homo sapiens_hsa05030 | 0.50024383 |
87 | * Pancreatic secretion_Homo sapiens_hsa04972 | 0.48689473 |
88 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.48141271 |
89 | Melanogenesis_Homo sapiens_hsa04916 | 0.47835978 |
90 | Tight junction_Homo sapiens_hsa04530 | 0.47585317 |
91 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.46288652 |
92 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.45914213 |
93 | Endometrial cancer_Homo sapiens_hsa05213 | 0.45701878 |
94 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.44720158 |
95 | Axon guidance_Homo sapiens_hsa04360 | 0.42824394 |
96 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.40887471 |
97 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.40216333 |
98 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38909764 |
99 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38672803 |
100 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.36775324 |
101 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.36737873 |
102 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.35235971 |
103 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.35179227 |
104 | Glioma_Homo sapiens_hsa05214 | 0.34901621 |
105 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.32400996 |
106 | Bile secretion_Homo sapiens_hsa04976 | 0.31951269 |
107 | Prion diseases_Homo sapiens_hsa05020 | 0.31279800 |
108 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.30001800 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.29974901 |
110 | Adherens junction_Homo sapiens_hsa04520 | 0.29751305 |
111 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.28894262 |
112 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.28311368 |
113 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27302404 |
114 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.27246677 |
115 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.27010816 |
116 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.24621689 |
117 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.22761422 |
118 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22552139 |