S100A14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of skin barrier (GO:0061436)9.32826418
2regulation of water loss via skin (GO:0033561)8.95139446
3bundle of His cell to Purkinje myocyte communication (GO:0086069)8.05663832
4keratinocyte differentiation (GO:0030216)7.02590051
5intermediate filament organization (GO:0045109)6.87487967
6peptide cross-linking (GO:0018149)6.61633147
7multicellular organismal water homeostasis (GO:0050891)6.51862552
8water homeostasis (GO:0030104)5.75142507
9phospholipid efflux (GO:0033700)5.56918594
10epidermis development (GO:0008544)5.53984121
11epidermal cell differentiation (GO:0009913)5.47790691
12keratinocyte proliferation (GO:0043616)5.29860597
13gap junction assembly (GO:0016264)4.72626595
14keratinocyte development (GO:0003334)4.55194854
15positive regulation of keratinocyte differentiation (GO:0045618)4.43567069
16skin morphogenesis (GO:0043589)4.43248015
17intermediate filament cytoskeleton organization (GO:0045104)4.35568921
18negative regulation of keratinocyte proliferation (GO:0010839)4.33610818
19interferon-gamma secretion (GO:0072643)4.30568858
20polarized epithelial cell differentiation (GO:0030859)4.28600765
21intermediate filament-based process (GO:0045103)4.21595749
22regulation of cholesterol esterification (GO:0010872)4.20066537
23adhesion of symbiont to host cell (GO:0044650)4.15112064
24virion attachment to host cell (GO:0019062)4.15112064
25detection of bacterium (GO:0016045)4.10540049
26COPI coating of Golgi vesicle (GO:0048205)4.09713809
27Golgi transport vesicle coating (GO:0048200)4.09713809
28negative regulation of lipase activity (GO:0060192)4.06881885
29plasma lipoprotein particle assembly (GO:0034377)3.99796159
30sphingoid metabolic process (GO:0046519)3.98486453
31positive regulation of Cdc42 GTPase activity (GO:0043089)3.93180604
32sphingosine metabolic process (GO:0006670)3.92660008
33ectoderm development (GO:0007398)3.82650583
34regulation of chemokine secretion (GO:0090196)3.78334057
35cell-substrate junction assembly (GO:0007044)3.73469197
36detection of other organism (GO:0098543)3.72494461
37diol metabolic process (GO:0034311)3.66060224
38high-density lipoprotein particle remodeling (GO:0034375)3.63887140
39phosphatidylserine acyl-chain remodeling (GO:0036150)3.61364683
40protein-lipid complex assembly (GO:0065005)3.60302518
41epithelial cell differentiation involved in prostate gland development (GO:0060742)3.53853572
42regulation of ruffle assembly (GO:1900027)3.53343442
43antigen processing and presentation of endogenous antigen (GO:0019883)3.50426376
44intestinal epithelial cell development (GO:0060576)3.48951017
45phosphatidylinositol acyl-chain remodeling (GO:0036149)3.46058591
46negative regulation of cell fate specification (GO:0009996)3.32350894
47phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.28440768
48regulation of hair follicle development (GO:0051797)3.26273261
49surfactant homeostasis (GO:0043129)3.25904544
50negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)3.24392766
51regulation of keratinocyte differentiation (GO:0045616)3.23526597
52very-low-density lipoprotein particle assembly (GO:0034379)3.22987398
53positive regulation of epidermis development (GO:0045684)3.19956447
54negative regulation of cell fate commitment (GO:0010454)3.18630386
55ventricular cardiac muscle cell action potential (GO:0086005)3.17795529
56negative regulation of epidermis development (GO:0045683)3.17732177
57regulation of substrate adhesion-dependent cell spreading (GO:1900024)3.16819276
58adhesion of symbiont to host (GO:0044406)3.15784811
59atrioventricular valve morphogenesis (GO:0003181)3.15058593
60positive regulation of hair cycle (GO:0042635)3.14387858
61positive regulation of hair follicle development (GO:0051798)3.14387858
62hair follicle morphogenesis (GO:0031069)3.12983885
63regulation of dendritic cell antigen processing and presentation (GO:0002604)3.08981092
64skin development (GO:0043588)3.08244290
65regulation of epidermis development (GO:0045682)3.04677442
66regulation of cardioblast differentiation (GO:0051890)3.01002941
67reverse cholesterol transport (GO:0043691)2.98774962
68eyelid development in camera-type eye (GO:0061029)2.96499102
69regulation of keratinocyte proliferation (GO:0010837)2.96332162
70cellular copper ion homeostasis (GO:0006878)2.95847160
71regulation of Cdc42 GTPase activity (GO:0043088)2.94781299
72regulation of natural killer cell differentiation (GO:0032823)2.94703267
73L-serine transport (GO:0015825)2.94201921
74regulation of cytokine secretion involved in immune response (GO:0002739)2.93677287
75calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.92411991
76cardiac right ventricle morphogenesis (GO:0003215)2.91743813
77dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.91515977
78phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.91291986
79positive regulation of antigen processing and presentation (GO:0002579)2.89316580
80branching involved in mammary gland duct morphogenesis (GO:0060444)2.87235094
81epithelium development (GO:0060429)2.86040953
82cell adhesion mediated by integrin (GO:0033627)2.84992124
83positive regulation of substrate adhesion-dependent cell spreading (GO:1900026)2.84753857
84positive regulation of epidermal cell differentiation (GO:0045606)2.78676464
85epithelial cell-cell adhesion (GO:0090136)2.78617934
86cell-cell junction assembly (GO:0007043)2.77266000
87planar cell polarity pathway involved in neural tube closure (GO:0090179)2.77036971
88tight junction assembly (GO:0070830)2.76478793
89intestinal absorption (GO:0050892)2.75424686
90diterpenoid biosynthetic process (GO:0016102)2.75103043
91positive regulation of interleukin-8 secretion (GO:2000484)2.74187045
92GDP-mannose metabolic process (GO:0019673)2.74173732
93chemical homeostasis within a tissue (GO:0048875)2.73922603
94regulation of epidermal cell differentiation (GO:0045604)2.73904798
95molting cycle process (GO:0022404)2.72070170
96hair cycle process (GO:0022405)2.72070170
97regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.71738328
98protein localization to endosome (GO:0036010)2.71271658
99cell junction assembly (GO:0034329)2.71266362
100protein autoprocessing (GO:0016540)2.69166027
101establishment of tissue polarity (GO:0007164)2.67946852
102establishment of planar polarity (GO:0001736)2.67946852
103regulation of hair cycle (GO:0042634)2.67899027
104regulation of metalloenzyme activity (GO:0048552)2.66623548
105endosome organization (GO:0007032)2.65842814
106regulation of apoptotic process involved in morphogenesis (GO:1902337)2.62539387
107hepatocyte apoptotic process (GO:0097284)2.62512409
108phosphatidylcholine acyl-chain remodeling (GO:0036151)2.62332818
109regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.60765775
110regulation of phospholipase A2 activity (GO:0032429)2.60208996
111cell junction organization (GO:0034330)2.60049622
112renal filtration (GO:0097205)2.59453747
113viral transcription (GO:0019083)2.58858979
114regulation of transforming growth factor beta1 production (GO:0032908)2.58107403
115prostanoid biosynthetic process (GO:0046457)2.57340690
116prostaglandin biosynthetic process (GO:0001516)2.57340690
117positive regulation of pseudopodium assembly (GO:0031274)2.56782870
118regulation of cholesterol homeostasis (GO:2000188)2.55974304
119cholesterol efflux (GO:0033344)2.55036233
120regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.54904190
121morphogenesis of embryonic epithelium (GO:0016331)2.54474725
122phosphatidylserine metabolic process (GO:0006658)2.52821609
123regulation of interleukin-8 secretion (GO:2000482)2.52547317
124cytoskeletal anchoring at plasma membrane (GO:0007016)2.51090896
125activation of Rac GTPase activity (GO:0032863)2.51001377
126cell differentiation involved in embryonic placenta development (GO:0060706)2.50317093
127regulation of heart rate by cardiac conduction (GO:0086091)2.49475739
128hair follicle development (GO:0001942)2.48902291
129NADH metabolic process (GO:0006734)2.47167217
130renal absorption (GO:0070293)2.47149491
131negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.46583646
132serine transport (GO:0032329)2.46495385
133retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.46362013
134membrane budding (GO:0006900)2.45842748
135antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.44470221
136antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.44470221
137mammary gland epithelial cell proliferation (GO:0033598)2.43335301
138maintenance of gastrointestinal epithelium (GO:0030277)2.43184899
139positive regulation of cholesterol efflux (GO:0010875)2.42051683
140translational termination (GO:0006415)2.40318853
141lateral sprouting from an epithelium (GO:0060601)2.38342688
142regulation of antigen processing and presentation (GO:0002577)2.36367402
143regulation of transforming growth factor beta2 production (GO:0032909)2.35005469
144cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.34837704
145regulation of glomerular filtration (GO:0003093)2.34100112
146cell communication involved in cardiac conduction (GO:0086065)2.33975395
147desmosome organization (GO:0002934)12.1320105
148hemidesmosome assembly (GO:0031581)11.6188775
149keratinization (GO:0031424)11.3250738
150molting cycle (GO:0042303)11.0206440
151hair cycle (GO:0042633)11.0206440

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.24062245
2SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.17326959
3* P63_26484246_Chip-Seq_KERATINOCYTES_Human2.65048136
4TRIM28_21343339_ChIP-Seq_HEK293_Human2.60598124
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.54808603
6SOX9_24532713_ChIP-Seq_HFSC_Mouse2.37306986
7ESR2_21235772_ChIP-Seq_MCF-7_Human2.16771701
8SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.12518961
9SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.12518961
10FOXO3_23340844_ChIP-Seq_DLD1_Human2.04631309
11TP63_17297297_ChIP-ChIP_HaCaT_Human14.4516837
12* SOX2_20726797_ChIP-Seq_SW620_Human1.76978248
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.75221797
14RARG_19884340_ChIP-ChIP_MEFs_Mouse1.66204258
15STAT6_21828071_ChIP-Seq_BEAS2B_Human1.65277032
16ZNF263_19887448_ChIP-Seq_K562_Human1.65110695
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.64910133
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.60674933
19CDX2_20551321_ChIP-Seq_CACO-2_Human1.59869389
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.54400449
21AR_21909140_ChIP-Seq_LNCAP_Human1.51267781
22ESR1_20079471_ChIP-ChIP_T-47D_Human1.49811122
23RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.47856250
24ZNF217_24962896_ChIP-Seq_MCF-7_Human1.47838146
25RUNX1_27514584_Chip-Seq_MCF-7_Human1.47005799
26KLF5_25053715_ChIP-Seq_YYC3_Human1.46868319
27HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.46069933
28TCF4_18268006_ChIP-ChIP_LS174T_Human1.45136704
29SOX2_27498859_Chip-Seq_STOMACH_Mouse1.44521745
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.42970356
31GATA4_25053715_ChIP-Seq_YYC3_Human1.41327955
32RXR_22158963_ChIP-Seq_LIVER_Mouse1.40297469
33* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39381763
34STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.39243126
35KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.38378419
36NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.36817001
37ESR1_15608294_ChIP-ChIP_MCF-7_Human1.34382730
38* RACK7_27058665_Chip-Seq_MCF-7_Human1.33067654
39GATA6_25053715_ChIP-Seq_YYC3_Human1.31818782
40CJUN_26792858_Chip-Seq_BT549_Human1.28664386
41FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.25331415
42KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24534403
43PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.23943245
44* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.22579121
45HIF1A_21447827_ChIP-Seq_MCF-7_Human1.22529025
46EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.22424248
47AHR_22903824_ChIP-Seq_MCF-7_Human1.21308373
48FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.21130911
49PPAR_26484153_Chip-Seq_NCI-H1993_Human1.19139913
50* TP63_23658742_ChIP-Seq_EP156T_Human1.18101973
51* ATF3_27146783_Chip-Seq_COLON_Human1.15040734
52TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.13138323
53* TP63_22573176_ChIP-Seq_HFKS_Human1.12697969
54GATA3_24758297_ChIP-Seq_MCF-7_Human1.11015226
55TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10235725
56NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.10134058
57PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.10078869
58BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.07762860
59JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07627987
60FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.07619964
61EGR1_19032775_ChIP-ChIP_M12_Human1.07348265
62NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05975499
63TP53_20018659_ChIP-ChIP_R1E_Mouse1.05674543
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03982316
65* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02611027
66PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.00953550
67CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98781593
68JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98689295
69CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97538717
70RXR_22108803_ChIP-Seq_LS180_Human0.97002952
71ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96121579
72ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.95498936
73TP53_18474530_ChIP-ChIP_U2OS_Human0.94739255
74POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93897859
75TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93593966
76UBF1/2_26484160_Chip-Seq_HMECs_Human0.92647534
77SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92560061
78ARNT_22903824_ChIP-Seq_MCF-7_Human0.92543680
79ELF5_23300383_ChIP-Seq_T47D_Human0.92435406
80CHD1_26751641_Chip-Seq_LNCaP_Human0.89188861
81ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.89113703
82LXR_22158963_ChIP-Seq_LIVER_Mouse0.88062310
83NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.87479562
84BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.87050654
85P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.86261868
86SUZ12_27294783_Chip-Seq_ESCs_Mouse0.86256833
87LXR_22292898_ChIP-Seq_THP-1_Human0.85374596
88HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84910284
89* GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.84415143
90AR_21572438_ChIP-Seq_LNCaP_Human0.84200895
91CLOCK_20551151_ChIP-Seq_293T_Human0.84200284
92BCAT_22108803_ChIP-Seq_LS180_Human0.83435785
93ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.83097822
94ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.82796117
95CTCF_27219007_Chip-Seq_Bcells_Human0.81055015
96FOXM1_26456572_ChIP-Seq_MCF-7_Human0.80813715
97GATA2_21666600_ChIP-Seq_HMVEC_Human0.80175066
98GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.79792188
99* EGR1_23403033_ChIP-Seq_LIVER_Mouse0.79785537
100ERG_21242973_ChIP-ChIP_JURKAT_Human0.78343508
101NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.78063222
102FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.78024530
103CEBPB_22108803_ChIP-Seq_LS180_Human0.77261588
104JARID2_20075857_ChIP-Seq_MESCs_Mouse0.76695709
105CTCF_20526341_ChIP-Seq_ESCs_Human0.74149031
106* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.72646835
107SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.70897905
108GATA6_21074721_ChIP-Seq_CACO-2_Human0.70582331
109THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.70549500
110NANOG_18692474_ChIP-Seq_MEFs_Mouse0.70504609
111ELK3_25401928_ChIP-Seq_HUVEC_Human0.70369422
112NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.69900713
113ERG_20517297_ChIP-Seq_VCAP_Human0.69802046
114TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.69659340
115SRY_22984422_ChIP-ChIP_TESTIS_Rat0.68917870
116EOMES_21245162_ChIP-Seq_HESCs_Human0.67108412
117DNAJC2_21179169_ChIP-ChIP_NT2_Human0.67056675
118CREB1_26743006_Chip-Seq_LNCaP_Human0.66275168
119TP53_16413492_ChIP-PET_HCT116_Human0.65780470
120* SA1_27219007_Chip-Seq_ERYTHROID_Human0.63888601
121SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.63269733
122BCOR_27268052_Chip-Seq_Bcells_Human0.63091664
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.61790208
124CSB_26484114_Chip-Seq_FIBROBLAST_Human0.60970591
125SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.60637446
126P300_27058665_Chip-Seq_ZR-75-30cells_Human0.60290113
127CDX2_22108803_ChIP-Seq_LS180_Human0.59733607
128PPARA_22158963_ChIP-Seq_LIVER_Mouse0.59227101
129EZH2_27294783_Chip-Seq_ESCs_Mouse0.58552671
130KDM2B_26808549_Chip-Seq_K562_Human0.57972681
131RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.57440556
132SMC4_20622854_ChIP-Seq_HELA_Human0.55996967
133CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.55550625

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat6.73360665
2MP0002796_impaired_skin_barrier6.09419839
3MP0010234_abnormal_vibrissa_follicle5.31704588
4MP0005275_abnormal_skin_tensile4.62669811
5MP0000579_abnormal_nail_morphology4.58240666
6MP0000383_abnormal_hair_follicle3.79740003
7MP0005501_abnormal_skin_physiology3.70857791
8MP0010678_abnormal_skin_adnexa3.61038327
9MP0001346_abnormal_lacrimal_gland3.28132367
10MP0002098_abnormal_vibrissa_morphology3.25190460
11MP0001216_abnormal_epidermal_layer3.03127887
12MP0002060_abnormal_skin_morphology2.98401146
13MP0003453_abnormal_keratinocyte_physiol2.94142515
14MP0009840_abnormal_foam_cell2.92913783
15MP0003941_abnormal_skin_development2.91159118
16MP0000467_abnormal_esophagus_morphology2.63807266
17MP0000647_abnormal_sebaceous_gland2.63160854
18MP0004381_abnormal_hair_follicle2.58133331
19MP0003705_abnormal_hypodermis_morpholog2.51226924
20MP0010771_integument_phenotype2.50077109
21MP0000377_abnormal_hair_follicle2.37545708
22MP0004947_skin_inflammation2.27242108
23MP0000427_abnormal_hair_cycle2.26734089
24MP0000762_abnormal_tongue_morphology2.12171630
25MP0005360_urolithiasis2.01118279
26MP0003566_abnormal_cell_adhesion1.77221156
27MP0001873_stomach_inflammation1.61041609
28MP0010352_gastrointestinal_tract_polyps1.58716714
29MP0002234_abnormal_pharynx_morphology1.56405245
30MP0005451_abnormal_body_composition1.55528691
31MP0004019_abnormal_vitamin_homeostasis1.50801892
32MP0000566_synostosis1.49774335
33MP0001348_abnormal_lacrimal_gland1.46910991
34MP0009931_abnormal_skin_appearance1.44635746
35MP0001851_eye_inflammation1.39219361
36MP0001849_ear_inflammation1.38154647
37MP0003806_abnormal_nucleotide_metabolis1.37835610
38MP0009780_abnormal_chondrocyte_physiolo1.36515158
39MP0000685_abnormal_immune_system1.36431592
40MP0002876_abnormal_thyroid_physiology1.29408599
41MP0004264_abnormal_extraembryonic_tissu1.29092883
42MP0000678_abnormal_parathyroid_gland1.27830650
43MP0000367_abnormal_coat/_hair1.27676903
44MP0004185_abnormal_adipocyte_glucose1.27374074
45MP0001191_abnormal_skin_condition1.26630356
46MP0004782_abnormal_surfactant_physiolog1.21807269
47MP0001243_abnormal_dermal_layer1.16927073
48MP0008260_abnormal_autophagy1.13653005
49MP0001666_abnormal_nutrient_absorption1.13339139
50MP0002877_abnormal_melanocyte_morpholog1.11643104
51MP0005023_abnormal_wound_healing1.05191193
52MP0002009_preneoplasia1.04126621
53MP0008004_abnormal_stomach_pH1.02282506
54MP0010030_abnormal_orbit_morphology1.02182730
55MP0000537_abnormal_urethra_morphology1.02066943
56MP0009053_abnormal_anal_canal1.01620228
57MP0000470_abnormal_stomach_morphology0.95570086
58MP0000538_abnormal_urinary_bladder0.92609017
59MP0000627_abnormal_mammary_gland0.92051164
60MP0002277_abnormal_respiratory_mucosa0.88648699
61MP0000613_abnormal_salivary_gland0.87742616
62MP0005310_abnormal_salivary_gland0.86436268
63MP0010155_abnormal_intestine_physiology0.85806312
64MP0003315_abnormal_perineum_morphology0.82685264
65MP0000516_abnormal_urinary_system0.78471439
66MP0005367_renal/urinary_system_phenotyp0.78471439
67MP0005083_abnormal_biliary_tract0.77054898
68MP0005085_abnormal_gallbladder_physiolo0.74447009
69MP0004272_abnormal_basement_membrane0.74285964
70MP0000465_gastrointestinal_hemorrhage0.71164997
71MP0003950_abnormal_plasma_membrane0.70779553
72MP0009643_abnormal_urine_homeostasis0.70433739
73MP0004043_abnormal_pH_regulation0.70132381
74MP0001340_abnormal_eyelid_morphology0.69422324
75MP0000858_altered_metastatic_potential0.68595853
76MP0001765_abnormal_ion_homeostasis0.68041093
77MP0008789_abnormal_olfactory_epithelium0.66841269
78MP0009379_abnormal_foot_pigmentation0.65833669
79MP0005647_abnormal_sex_gland0.64520642
80MP0004957_abnormal_blastocyst_morpholog0.64407909
81MP0005365_abnormal_bile_salt0.63746342
82MP0003183_abnormal_peptide_metabolism0.63008574
83MP0002282_abnormal_trachea_morphology0.62767156
84MP0005076_abnormal_cell_differentiation0.62760138
85MP0010329_abnormal_lipoprotein_level0.62218951
86MP0002166_altered_tumor_susceptibility0.56991535
87MP0003878_abnormal_ear_physiology0.56913973
88MP0005377_hearing/vestibular/ear_phenot0.56913973
89MP0000462_abnormal_digestive_system0.55901453
90MP0005257_abnormal_intraocular_pressure0.55710602
91MP0001835_abnormal_antigen_presentation0.55589979
92MP0003755_abnormal_palate_morphology0.55223978
93MP0003763_abnormal_thymus_physiology0.54663267
94MP0002006_tumorigenesis0.54036353
95MP0000490_abnormal_crypts_of0.53465564
96MP0003191_abnormal_cellular_cholesterol0.51187908
97MP0005075_abnormal_melanosome_morpholog0.51002892
98MP0005636_abnormal_mineral_homeostasis0.50675608
99MP0004885_abnormal_endolymph0.49318611
100MP0002148_abnormal_hypersensitivity_rea0.48374926
101MP0005248_abnormal_Harderian_gland0.48145241
102MP0002139_abnormal_hepatobiliary_system0.47898270
103MP0002086_abnormal_extraembryonic_tissu0.47480890
104MP0009384_cardiac_valve_regurgitation0.47082021
105MP0004858_abnormal_nervous_system0.47052810
106MP0001881_abnormal_mammary_gland0.46187273
107MP0006054_spinal_hemorrhage0.45770681
108MP0001727_abnormal_embryo_implantation0.44568586
109MP0005666_abnormal_adipose_tissue0.44006606
110MP0002233_abnormal_nose_morphology0.43128867
111MP0003045_fibrosis0.42671570
112MP0000477_abnormal_intestine_morphology0.40684485
113MP0002089_abnormal_postnatal_growth/wei0.40637693
114MP0006082_CNS_inflammation0.39358164
115MP0002095_abnormal_skin_pigmentation0.38997951
116MP0003693_abnormal_embryo_hatching0.38417896
117MP0005409_darkened_coat_color0.38405917
118MP0003300_gastrointestinal_ulcer0.38404127
119MP0002177_abnormal_outer_ear0.38232965
120MP0002136_abnormal_kidney_physiology0.37976102
121MP0003638_abnormal_response/metabolism_0.37118301
122MP0002138_abnormal_hepatobiliary_system0.36414041
123MP0002896_abnormal_bone_mineralization0.36265428
124MP0003436_decreased_susceptibility_to0.35782942
125MP0001784_abnormal_fluid_regulation0.35077399
126MP0003936_abnormal_reproductive_system0.34830662
127MP0003448_altered_tumor_morphology0.34694677
128MP0004510_myositis0.33432194
129MP0005381_digestive/alimentary_phenotyp0.33310970
130MP0003329_amyloid_beta_deposits0.32625554
131MP0002249_abnormal_larynx_morphology0.32330740
132MP0005375_adipose_tissue_phenotype0.32233998
133MP0002111_abnormal_tail_morphology0.31953797
134MP0003866_abnormal_defecation0.30199694
135MP0001853_heart_inflammation0.30162771

Predicted human phenotypes

RankGene SetZ-score
1Onycholysis (HP:0001806)8.26861089
2Plantar hyperkeratosis (HP:0007556)7.37781152
3Fragile nails (HP:0001808)7.28494613
4Milia (HP:0001056)7.23261841
5Hypotrichosis (HP:0001006)6.86138191
6Woolly hair (HP:0002224)6.85583283
7Right ventricular cardiomyopathy (HP:0011663)6.81269024
8Abnormality of nail color (HP:0100643)6.23557392
9Palmoplantar hyperkeratosis (HP:0000972)6.00047777
10Palmar hyperkeratosis (HP:0010765)5.62813242
11Increased IgE level (HP:0003212)5.58543071
12Pili torti (HP:0003777)5.54347565
13Thick nail (HP:0001805)5.38798539
14Nail dystrophy (HP:0008404)5.14674098
15Atrophic scars (HP:0001075)4.78472244
16Lip pit (HP:0100267)4.37687624
17Abnormal blistering of the skin (HP:0008066)4.35920266
18Alopecia of scalp (HP:0002293)4.35219657
19Congenital ichthyosiform erythroderma (HP:0007431)3.93317617
20Erythema (HP:0010783)3.70106148
21Malnutrition (HP:0004395)3.48959445
22Abnormal hair laboratory examination (HP:0003328)3.42259919
23Erythroderma (HP:0001019)3.35685035
24Ridged nail (HP:0001807)3.33303057
25Abnormality of the neuromuscular junction (HP:0003398)3.33075833
26Fatigable weakness (HP:0003473)3.33075833
27Parakeratosis (HP:0001036)3.27956139
28Abnormality of the salivary glands (HP:0010286)3.23085971
29Hypoplasia of dental enamel (HP:0006297)3.19718724
30Oral leukoplakia (HP:0002745)3.05103203
31Absent eyelashes (HP:0000561)3.02597673
32Ventricular tachycardia (HP:0004756)3.02419109
33Abnormality of the gastric mucosa (HP:0004295)3.01643146
34Dry hair (HP:0011359)2.94750762
35Sparse eyelashes (HP:0000653)2.94050736
36Aplasia cutis congenita (HP:0001057)2.93369586
37Curly hair (HP:0002212)2.91682824
38Ectropion (HP:0000656)2.87352611
39Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.86932300
40Conjunctival hamartoma (HP:0100780)2.84991937
41Abnormality of secondary sexual hair (HP:0009888)2.84206965
42Abnormality of the axillary hair (HP:0100134)2.84206965
43Natal tooth (HP:0000695)2.77786713
44Palmoplantar keratoderma (HP:0000982)2.77648655
45Selective tooth agenesis (HP:0001592)2.76503759
46Corneal erosion (HP:0200020)2.72747413
47Advanced eruption of teeth (HP:0006288)2.71403194
48Hypohidrosis (HP:0000966)2.66886480
49Amelogenesis imperfecta (HP:0000705)2.65323160
50Abnormality of the labia majora (HP:0012881)2.61953798
51Follicular hyperkeratosis (HP:0007502)2.61369234
52Keratoconjunctivitis (HP:0001096)2.56396872
53Abnormality of placental membranes (HP:0011409)2.55597451
54Amniotic constriction ring (HP:0009775)2.55597451
55Hyperactive renin-angiotensin system (HP:0000841)2.50462052
56Ankyloglossia (HP:0010296)2.45215201
57Pruritus (HP:0000989)2.44958631
58Congenital, generalized hypertrichosis (HP:0004540)2.42312319
59Septate vagina (HP:0001153)2.42206591
60Pustule (HP:0200039)2.39866313
61Brittle hair (HP:0002299)2.35927137
62Hyporeflexia of lower limbs (HP:0002600)2.34885865
63Epidermoid cyst (HP:0200040)2.33855032
64Distal lower limb muscle weakness (HP:0009053)2.32835448
65Fragile skin (HP:0001030)2.30570189
66Gangrene (HP:0100758)2.30358950
67Interstitial pulmonary disease (HP:0006530)2.24452358
68Double outlet right ventricle (HP:0001719)2.23211868
69Congenital malformation of the right heart (HP:0011723)2.23211868
70Abnormality of hair growth rate (HP:0011363)2.22699915
71Slow-growing hair (HP:0002217)2.22699915
72Pterygium (HP:0001059)2.20590707
73Flat acetabular roof (HP:0003180)2.17863554
74Hypoplasia of the uterus (HP:0000013)2.15829995
75Esophageal atresia (HP:0002032)2.15456803
76Acanthosis nigricans (HP:0000956)2.11834276
77Hyperhidrosis (HP:0000975)2.09004102
78Blepharitis (HP:0000498)2.08944656
79Sparse scalp hair (HP:0002209)2.07853146
80Eczematoid dermatitis (HP:0000976)2.07299233
81Type I diabetes mellitus (HP:0100651)2.07270003
82Oligodontia (HP:0000677)2.06401842
83Abnormality of monocarboxylic acid metabolism (HP:0010996)2.03491720
84Aplasia/Hypoplasia of the spleen (HP:0010451)2.02610935
85Abnormality of the dental root (HP:0006486)2.02368514
86Taurodontia (HP:0000679)2.02368514
87Abnormality of permanent molar morphology (HP:0011071)2.02368514
88Popliteal pterygium (HP:0009756)1.97959803
89Anonychia (HP:0001798)1.97070746
90Skin ulcer (HP:0200042)1.96233238
91Absent hair (HP:0002298)1.94685798
92Dehydration (HP:0001944)1.93712771
93Abnormality of the fingernails (HP:0001231)1.91028918
94Unilateral renal agenesis (HP:0000122)1.87898545
95Hypoparathyroidism (HP:0000829)1.85926040
96Hypergammaglobulinemia (HP:0010702)1.83445916
97Abnormality of molar (HP:0011077)1.82859443
98Abnormality of molar morphology (HP:0011070)1.82859443
99Chronic mucocutaneous candidiasis (HP:0002728)1.82358650
100Recurrent cutaneous fungal infections (HP:0011370)1.82358650
101Ureteral stenosis (HP:0000071)1.80801919
102Abnormality of oral frenula (HP:0000190)1.80022119
103Multifactorial inheritance (HP:0001426)1.79810221
104Concave nail (HP:0001598)1.79474614
105Cheilitis (HP:0100825)1.79052086
106Hypodontia (HP:0000668)1.78448301
107Abnormality of the dental pulp (HP:0006479)1.77017627
108Increased connective tissue (HP:0009025)1.76702246
109Nasolacrimal duct obstruction (HP:0000579)1.75224916
110Labial hypoplasia (HP:0000066)1.74879705
111Intrahepatic cholestasis (HP:0001406)1.74640287
112Laryngomalacia (HP:0001601)1.71937879
113Hoarse voice (HP:0001609)1.70039263
114Neonatal onset (HP:0003623)1.70036868
115Carious teeth (HP:0000670)1.66813629
116Asplenia (HP:0001746)1.66508123
117Hypercortisolism (HP:0001578)1.65640571
118Upper limb muscle weakness (HP:0003484)1.64298668
119Ventricular fibrillation (HP:0001663)1.64212977
120Round ear (HP:0100830)1.64074000
121Ureteral obstruction (HP:0006000)1.63967893
122Split foot (HP:0001839)1.63737818
123Renal tubular acidosis (HP:0001947)1.63733660
124Ureteral duplication (HP:0000073)1.63487725
125Aplasia/hypoplasia of the uterus (HP:0008684)1.62229634
126Abnormality of the distal phalanges of the toes (HP:0010182)1.62225292
127Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.62183810
128Premature loss of primary teeth (HP:0006323)1.61797892
129Skin pits (HP:0100276)1.61261389
130Corneal dystrophy (HP:0001131)1.61221048
131Myopathic facies (HP:0002058)1.60772825
132Hypoplastic female external genitalia (HP:0012815)1.60772535
133Trismus (HP:0000211)1.59071669
134Type 1 muscle fiber predominance (HP:0003803)1.58462983
135Absent phalangeal crease (HP:0006109)1.56730473
136Villous atrophy (HP:0011473)1.53480198
137Abnormality of small intestinal villus morphology (HP:0011472)1.53480198
138Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.51008572
139Hypoplastic labia majora (HP:0000059)1.50123393
140Hamartoma of the eye (HP:0010568)1.49765711
141Muscle fiber inclusion bodies (HP:0100299)1.49733078
142Nemaline bodies (HP:0003798)1.45200028

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA24.97558335
2MST1R4.16845129
3MST43.87206395
4FER3.19667804
5NME13.19562964
6PBK3.16233648
7MAPKAPK33.12681391
8MAP3K32.99579519
9RPS6KB22.55903473
10LMTK22.53923451
11LATS12.45783617
12MAP3K122.36760476
13EPHB22.34242224
14MAP3K142.34216884
15EPHA32.33432716
16PDK22.15727838
17MAP3K22.08041750
18SIK12.04006108
19ERN11.96605579
20PTK61.92719948
21EPHB11.90919728
22ERBB31.89574351
23NME21.83853511
24TRPM71.77597950
25MAP2K21.75077327
26FRK1.68942558
27LRRK21.68663102
28STK241.66848398
29TAOK11.57740289
30PIM21.57510908
31DYRK1B1.46752418
32MET1.42849976
33PIK3CG1.42544019
34FGFR41.41669933
35ARAF1.41360682
36SIK31.38990518
37TESK11.31595841
38PDGFRA1.29934361
39MUSK1.25662204
40MAP3K11.24420085
41EEF2K1.22698083
42NTRK11.21907573
43BCR1.21865853
44TBK11.20889280
45TESK21.20270429
46MAP3K71.19277870
47PTK21.16311573
48IKBKE1.15115045
49NLK1.14586948
50SMG11.14260866
51STK101.12309592
52MAPKAPK51.06044253
53TRIB31.05216398
54PRKCI1.04789104
55TYK21.03665106
56MAP2K61.03082790
57MAP2K11.02600352
58TTN1.00639282
59CDK120.97229954
60FGFR30.92839246
61DYRK30.92751372
62NEK60.92654075
63FLT30.92366498
64SCYL20.92201341
65MAP3K110.89619780
66NEK10.84718602
67CHUK0.84036072
68EIF2AK10.83685981
69RPS6KA40.81967540
70MAPKAPK20.79815111
71IRAK30.75631568
72RIPK10.73323627
73MAP3K90.71546661
74TGFBR10.71418993
75MAPK150.68975823
76PRKG20.68396211
77BLK0.66650681
78TRIM280.65717850
79ERBB40.65678566
80CDK60.65337125
81ABL20.64745143
82IKBKB0.61441169
83STK390.60544938
84GRK60.57017515
85KSR20.56411653
86ERBB20.55527202
87BMPR1B0.55298978
88PDGFRB0.54974098
89FGFR20.54829041
90PDPK10.53469257
91EIF2AK30.52173133
92FGFR10.51097547
93LIMK10.49984473
94OBSCN0.49704764
95DDR20.48795059
96DMPK0.48761561
97ITK0.48760390
98MAP2K30.48111162
99MYLK0.46245892
100ILK0.44344005
101ACVR1B0.43871261
102JAK20.42830255
103RPS6KA10.41966232
104MATK0.41593479
105MAP3K130.41102480
106STK30.40925894
107MAP3K60.39804375
108RPS6KB10.39479450
109MTOR0.37952080
110TGFBR20.34398707
111BRAF0.34165457
112STK380.33938408
113MAP3K80.31961037
114PRKD10.31761309
115PRKAA20.31549110
116PRKD20.30470092
117LATS20.30098761
118CDK30.28998002
119BMPR20.28273761
120PRKCD0.27876413
121CAMK2G0.27544622
122TEC0.26850873
123PAK40.26780801
124SRC0.26766669
125PIK3CA0.26443282
126RPS6KA20.26173717
127JAK10.25007166
128GRK10.24661427
129BMX0.23683538
130RET0.22943783
131CAMK2D0.22691056
132CDK70.22282977
133HCK0.21992528
134AKT20.21910829
135ROCK20.21018665
136STK110.20682114
137CDC42BPA0.20654323
138NUAK10.20281351
139JAK30.19124161
140STK38L0.17772568
141PRKCE0.17718280
142PKN20.17459324
143BTK0.16568142

Predicted pathways (KEGG)

RankGene SetZ-score
1Linoleic acid metabolism_Homo sapiens_hsa005913.59912104
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.51972375
3Vitamin digestion and absorption_Homo sapiens_hsa049773.06133056
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.58049897
5Arachidonic acid metabolism_Homo sapiens_hsa005902.42052931
6Cyanoamino acid metabolism_Homo sapiens_hsa004602.37418155
7Histidine metabolism_Homo sapiens_hsa003402.31714848
8Galactose metabolism_Homo sapiens_hsa000522.17577990
9Arginine biosynthesis_Homo sapiens_hsa002202.15193679
10Phenylalanine metabolism_Homo sapiens_hsa003602.06537836
11Ether lipid metabolism_Homo sapiens_hsa005652.03693730
12Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.00592379
132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.92753123
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.92217003
15Fructose and mannose metabolism_Homo sapiens_hsa000511.88774390
16ECM-receptor interaction_Homo sapiens_hsa045121.85132404
17Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.84584756
18PPAR signaling pathway_Homo sapiens_hsa033201.78616878
19Adherens junction_Homo sapiens_hsa045201.78142455
20Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.73447548
21Basal cell carcinoma_Homo sapiens_hsa052171.71751849
22Tight junction_Homo sapiens_hsa045301.67777947
23Chemical carcinogenesis_Homo sapiens_hsa052041.61811086
24Toxoplasmosis_Homo sapiens_hsa051451.60647821
25Amoebiasis_Homo sapiens_hsa051461.60289371
26Sphingolipid metabolism_Homo sapiens_hsa006001.58609340
27Small cell lung cancer_Homo sapiens_hsa052221.52950566
28Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.51144204
29Fat digestion and absorption_Homo sapiens_hsa049751.50818577
30Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.50393200
31Bladder cancer_Homo sapiens_hsa052191.45057285
32Ribosome_Homo sapiens_hsa030101.44478947
33Hippo signaling pathway_Homo sapiens_hsa043901.42300447
34Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.41192170
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.40116461
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.37345507
37Central carbon metabolism in cancer_Homo sapiens_hsa052301.35630526
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.35386593
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.30636396
40Arginine and proline metabolism_Homo sapiens_hsa003301.28170419
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.27333394
42VEGF signaling pathway_Homo sapiens_hsa043701.24191592
43Sulfur metabolism_Homo sapiens_hsa009201.23445407
44Steroid hormone biosynthesis_Homo sapiens_hsa001401.22705582
45Pertussis_Homo sapiens_hsa051331.21894993
46Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.19661498
47Proteoglycans in cancer_Homo sapiens_hsa052051.19274194
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.19137537
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.16429139
50Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16368392
51Pentose phosphate pathway_Homo sapiens_hsa000301.12064274
52Mineral absorption_Homo sapiens_hsa049781.11399374
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.10436014
54Steroid biosynthesis_Homo sapiens_hsa001001.09485591
55Hepatitis C_Homo sapiens_hsa051601.08482521
56Hedgehog signaling pathway_Homo sapiens_hsa043401.08326836
57Fatty acid degradation_Homo sapiens_hsa000711.04067738
58Starch and sucrose metabolism_Homo sapiens_hsa005001.03151553
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01694253
60Vibrio cholerae infection_Homo sapiens_hsa051101.01049284
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99084118
62Leishmaniasis_Homo sapiens_hsa051400.99041903
63Antigen processing and presentation_Homo sapiens_hsa046120.98834904
64Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.97950058
65Dorso-ventral axis formation_Homo sapiens_hsa043200.96107785
66p53 signaling pathway_Homo sapiens_hsa041150.93654612
67Thyroid cancer_Homo sapiens_hsa052160.93412615
68NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93401109
69ErbB signaling pathway_Homo sapiens_hsa040120.92732616
70Tyrosine metabolism_Homo sapiens_hsa003500.90808561
71Pancreatic secretion_Homo sapiens_hsa049720.90336308
72Glutathione metabolism_Homo sapiens_hsa004800.90096436
73TNF signaling pathway_Homo sapiens_hsa046680.89292576
74Carbon metabolism_Homo sapiens_hsa012000.87960360
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87782981
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.85950976
77Retinol metabolism_Homo sapiens_hsa008300.84530392
78Focal adhesion_Homo sapiens_hsa045100.83704558
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83423740
80GnRH signaling pathway_Homo sapiens_hsa049120.80734489
81TGF-beta signaling pathway_Homo sapiens_hsa043500.77437914
82beta-Alanine metabolism_Homo sapiens_hsa004100.76803072
83Caffeine metabolism_Homo sapiens_hsa002320.76478326
84Salivary secretion_Homo sapiens_hsa049700.76295603
85Pyruvate metabolism_Homo sapiens_hsa006200.76033249
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.75881683
87Melanogenesis_Homo sapiens_hsa049160.74616946
88Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74042233
89Renin-angiotensin system_Homo sapiens_hsa046140.73266804
90MicroRNAs in cancer_Homo sapiens_hsa052060.71910311
91Bile secretion_Homo sapiens_hsa049760.71633445
92Primary immunodeficiency_Homo sapiens_hsa053400.69901131
93Osteoclast differentiation_Homo sapiens_hsa043800.69618134
94Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68669948
95Pathways in cancer_Homo sapiens_hsa052000.68253615
96Salmonella infection_Homo sapiens_hsa051320.67925402
97Axon guidance_Homo sapiens_hsa043600.67391797
98Endocytosis_Homo sapiens_hsa041440.67245854
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.66808309
100Ras signaling pathway_Homo sapiens_hsa040140.66562177
101Apoptosis_Homo sapiens_hsa042100.65634144
102Inositol phosphate metabolism_Homo sapiens_hsa005620.65480508
103Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.65472729
104Biosynthesis of amino acids_Homo sapiens_hsa012300.65401222
105Glycerolipid metabolism_Homo sapiens_hsa005610.64588459
106Acute myeloid leukemia_Homo sapiens_hsa052210.64393530
107Nitrogen metabolism_Homo sapiens_hsa009100.62855681
108AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.62682986
109Glycerophospholipid metabolism_Homo sapiens_hsa005640.62014205
110African trypanosomiasis_Homo sapiens_hsa051430.61603915
111Pancreatic cancer_Homo sapiens_hsa052120.61432704
112Fatty acid metabolism_Homo sapiens_hsa012120.61014869
113Insulin signaling pathway_Homo sapiens_hsa049100.60136642
114Fatty acid elongation_Homo sapiens_hsa000620.60021107
115Primary bile acid biosynthesis_Homo sapiens_hsa001200.59584205
116Influenza A_Homo sapiens_hsa051640.59405506
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.59150568
118Prolactin signaling pathway_Homo sapiens_hsa049170.56946426
119Legionellosis_Homo sapiens_hsa051340.56731040
120Gastric acid secretion_Homo sapiens_hsa049710.56704515
121Tuberculosis_Homo sapiens_hsa051520.55389073
122RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.54847077
123Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54177721
124Toll-like receptor signaling pathway_Homo sapiens_hsa046200.53318432
125Melanoma_Homo sapiens_hsa052180.52653597
126Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.51355062
127Rap1 signaling pathway_Homo sapiens_hsa040150.50921446
128Endometrial cancer_Homo sapiens_hsa052130.50701151
129Renal cell carcinoma_Homo sapiens_hsa052110.48977416
130Other glycan degradation_Homo sapiens_hsa005110.48587880
131Wnt signaling pathway_Homo sapiens_hsa043100.48057230
132Intestinal immune network for IgA production_Homo sapiens_hsa046720.47619699
133Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47327422
134Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47296460
135Insulin resistance_Homo sapiens_hsa049310.46777964
136Vascular smooth muscle contraction_Homo sapiens_hsa042700.46487438
137Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46222694
138Glucagon signaling pathway_Homo sapiens_hsa049220.45627354
139Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44458319
140Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.43611515
141ABC transporters_Homo sapiens_hsa020100.43101537
142Malaria_Homo sapiens_hsa051440.43028036
143Shigellosis_Homo sapiens_hsa051310.42693368
144Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41818122
145Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41175701
146Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39991525
147Protein digestion and absorption_Homo sapiens_hsa049740.38611992
148N-Glycan biosynthesis_Homo sapiens_hsa005100.36415383
149Chronic myeloid leukemia_Homo sapiens_hsa052200.36341855
150Fatty acid biosynthesis_Homo sapiens_hsa000610.35853751
151Metabolic pathways_Homo sapiens_hsa011000.33885114

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »