S100A9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1disruption of cells of other organism involved in symbiotic interaction (GO:0051818)9.99374969
2killing of cells in other organism involved in symbiotic interaction (GO:0051883)9.99374969
3* leukocyte migration involved in inflammatory response (GO:0002523)9.07259067
4* leukocyte aggregation (GO:0070486)8.99559717
5* defense response to fungus (GO:0050832)8.31178354
6response to peptidoglycan (GO:0032494)7.90795279
7disruption of cells of other organism (GO:0044364)7.53484258
8killing of cells of other organism (GO:0031640)7.53484258
9respiratory burst (GO:0045730)7.31857592
10* response to fungus (GO:0009620)7.14327517
11neutrophil mediated immunity (GO:0002446)7.11727760
12negative regulation of cell killing (GO:0031342)6.91509068
13negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.91509068
14cellular extravasation (GO:0045123)6.85290189
15neutrophil activation involved in immune response (GO:0002283)6.41855457
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.11671627
17production of molecular mediator involved in inflammatory response (GO:0002532)6.06290097
18positive regulation by symbiont of host defense response (GO:0052509)5.94787305
19modulation by symbiont of host defense response (GO:0052031)5.94787305
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.94787305
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.94787305
22positive regulation by organism of defense response of other organism involved in symbiotic interact5.94787305
23modulation by symbiont of host immune response (GO:0052553)5.94787305
24detection of bacterium (GO:0016045)5.78049162
25hydrogen peroxide biosynthetic process (GO:0050665)5.72095298
26regulation of myeloid leukocyte mediated immunity (GO:0002886)5.65291536
27* sequestering of metal ion (GO:0051238)5.61699998
28pentose-phosphate shunt (GO:0006098)5.61329862
29neutrophil activation (GO:0042119)5.59439261
30superoxide anion generation (GO:0042554)5.53224219
31positive regulation of gamma-delta T cell activation (GO:0046645)5.48888461
32regulation of leukocyte degranulation (GO:0043300)5.41645780
33reactive oxygen species biosynthetic process (GO:1903409)5.39911097
34myeloid leukocyte mediated immunity (GO:0002444)5.37532469
35detection of other organism (GO:0098543)5.35972879
36antigen processing and presentation of endogenous antigen (GO:0019883)5.26125348
37macrophage differentiation (GO:0030225)5.20619333
38antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.18672417
39granulocyte activation (GO:0036230)5.16326135
40macrophage activation involved in immune response (GO:0002281)5.10846076
41NADPH regeneration (GO:0006740)5.02490565
42leukotriene metabolic process (GO:0006691)4.96099297
43regulation of regulated secretory pathway (GO:1903305)4.88743000
44phagosome maturation (GO:0090382)4.87859536
45positive regulation of mast cell activation (GO:0033005)4.82645279
46leukotriene biosynthetic process (GO:0019370)4.80482168
47antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.66052688
48negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.65346471
49detection of molecule of bacterial origin (GO:0032490)4.61949798
50detection of biotic stimulus (GO:0009595)4.59648569
51regulation of mast cell degranulation (GO:0043304)4.55247288
52Arp2/3 complex-mediated actin nucleation (GO:0034314)4.52412488
53mucosal immune response (GO:0002385)4.49855431
54positive regulation of mast cell activation involved in immune response (GO:0033008)4.46447025
55positive regulation of mast cell degranulation (GO:0043306)4.46447025
56adaptation of signaling pathway (GO:0023058)4.44052835
57* neutrophil chemotaxis (GO:0030593)4.41171132
58negative regulation of lymphocyte mediated immunity (GO:0002707)4.38886060
59* neutrophil migration (GO:1990266)4.29092811
60innate immune response in mucosa (GO:0002227)4.25429215
61organ or tissue specific immune response (GO:0002251)4.25324164
62cell killing (GO:0001906)4.25175738
63regulation of mast cell activation involved in immune response (GO:0033006)4.24802321
64immunoglobulin mediated immune response (GO:0016064)4.24416307
65regulation of mast cell activation (GO:0033003)4.21744589
66antibacterial humoral response (GO:0019731)4.21437238
67response to host immune response (GO:0052572)4.18156454
68response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.18156454
69regulation of interferon-beta biosynthetic process (GO:0045357)4.16223502
70regulation of B cell receptor signaling pathway (GO:0050855)4.14926952
71positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.12497277
72microglial cell activation (GO:0001774)4.11325344
73antimicrobial humoral response (GO:0019730)4.10719327
74* granulocyte migration (GO:0097530)4.04675865
75negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.98475681
76leukocyte mediated cytotoxicity (GO:0001909)3.95020746
77* chronic inflammatory response (GO:0002544)3.92150775
78response to host (GO:0075136)3.90537058
79response to host defenses (GO:0052200)3.90537058
80response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.90537058
81negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.90433679
82myeloid cell activation involved in immune response (GO:0002275)3.90344142
83macrophage activation (GO:0042116)3.89828326
84regulation of gamma-delta T cell activation (GO:0046643)3.89726098
85negative regulation of leukocyte mediated immunity (GO:0002704)3.88791088
86negative regulation of phagocytosis (GO:0050765)3.88585498
87negative regulation of growth of symbiont in host (GO:0044130)3.88279668
88negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.88279668
89modulation of growth of symbiont involved in interaction with host (GO:0044144)3.88279668
90regulation of growth of symbiont in host (GO:0044126)3.88279668
91positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.85330396
92antigen processing and presentation via MHC class Ib (GO:0002475)3.73206166
93defense response to Gram-positive bacterium (GO:0050830)3.72308375
94positive regulation of lamellipodium assembly (GO:0010592)3.71932237
95* granulocyte chemotaxis (GO:0071621)3.70038193
96glucose catabolic process (GO:0006007)3.69553587
97negative regulation of interleukin-10 production (GO:0032693)3.67771819
98response to interleukin-15 (GO:0070672)3.53502014
99negative regulation of interleukin-12 production (GO:0032695)3.53460299
100negative regulation of T cell mediated immunity (GO:0002710)3.53455730
101positive regulation of leukocyte degranulation (GO:0043302)3.51065165
102positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.47238760
103* leukocyte cell-cell adhesion (GO:0007159)3.43643629
104type I interferon signaling pathway (GO:0060337)3.43391330
105cellular response to type I interferon (GO:0071357)3.43391330
106response to type I interferon (GO:0034340)3.39521092
107leukocyte degranulation (GO:0043299)3.33101043
108B cell mediated immunity (GO:0019724)3.31691940
109actin nucleation (GO:0045010)3.30138793
110negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.25897539
111negative regulation of T-helper cell differentiation (GO:0045623)3.25897539
112defense response to protozoan (GO:0042832)3.24778861
113regulation of gamma-delta T cell differentiation (GO:0045586)3.24771494
114regulation of T-helper 2 cell differentiation (GO:0045628)3.24631558
115B cell receptor signaling pathway (GO:0050853)3.24097419
116positive regulation of regulated secretory pathway (GO:1903307)3.23618229
117modification by host of symbiont morphology or physiology (GO:0051851)3.19348114
118NADP metabolic process (GO:0006739)3.18393582
119negative regulation of erythrocyte differentiation (GO:0045647)3.18354850
120germinal center formation (GO:0002467)3.17852375
121negative regulation of interleukin-6 production (GO:0032715)3.16644237
122mast cell activation (GO:0045576)3.11914944
123interferon-gamma-mediated signaling pathway (GO:0060333)3.11751863
124regulation of tolerance induction (GO:0002643)3.11595179
125pentose metabolic process (GO:0019321)3.11132429
126* defense response to bacterium (GO:0042742)3.08623482
127interaction with symbiont (GO:0051702)3.06195676
128positive regulation of actin cytoskeleton reorganization (GO:2000251)3.05402197
129negative regulation of innate immune response (GO:0045824)3.04984326
130myeloid leukocyte activation (GO:0002274)3.03781100
131positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.02722697
132regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.01367342
133cellular response to interleukin-15 (GO:0071350)3.00973169
134positive regulation of cellular amide metabolic process (GO:0034250)3.00895938
135lipopolysaccharide-mediated signaling pathway (GO:0031663)3.00606311
136detection of external biotic stimulus (GO:0098581)2.99693391
137regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.99683529
138positive regulation of osteoblast proliferation (GO:0033690)2.98505388
139regulation of T cell tolerance induction (GO:0002664)2.98366871
140positive regulation of toll-like receptor signaling pathway (GO:0034123)2.96876909
141response to muramyl dipeptide (GO:0032495)2.95302526
142positive regulation of lamellipodium organization (GO:1902745)2.95008073
143regulation of natural killer cell differentiation (GO:0032823)2.94839680
144positive regulation of interleukin-4 production (GO:0032753)2.94651541
145negative regulation of cytokine production involved in immune response (GO:0002719)2.93867304
146negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.93595285
147positive regulation of B cell differentiation (GO:0045579)2.93282065
148positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.93207597
149negative regulation of type 2 immune response (GO:0002829)2.92585001
150* myeloid leukocyte migration (GO:0097529)2.91456366
151regulation of dendritic cell antigen processing and presentation (GO:0002604)2.91130702
152activated T cell proliferation (GO:0050798)2.89843397
153regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.84042686
154eosinophil migration (GO:0072677)2.83510225
155regulation of phagocytosis (GO:0050764)2.81264892
156regulation of B cell differentiation (GO:0045577)2.80054108
157phospholipid homeostasis (GO:0055091)2.78833543

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.54303782
2MYB_21317192_ChIP-Seq_ERMYB_Mouse4.84011512
3E2F7_22180533_ChIP-Seq_HELA_Human4.54631433
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse4.45045697
5IRF8_21731497_ChIP-ChIP_J774_Mouse4.20055066
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.63236871
7FOXM1_23109430_ChIP-Seq_U2OS_Human3.52092316
8BRD4_27068464_Chip-Seq_AML-cells_Mouse3.43897384
9VDR_21846776_ChIP-Seq_THP-1_Human3.40209689
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.32641380
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.31050200
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.10849158
13* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human3.07906140
14IRF8_27001747_Chip-Seq_BMDM_Mouse3.02401311
15* SPI1_23547873_ChIP-Seq_NB4_Human2.87233324
16RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.69719880
17SCL_19346495_ChIP-Seq_HPC-7_Human2.68000862
18VDR_24763502_ChIP-Seq_THP-1_Human2.64044839
19ESR1_15608294_ChIP-ChIP_MCF-7_Human2.36866673
20UTX_26944678_Chip-Seq_JUKART_Human2.26661537
21RUNX1_22412390_ChIP-Seq_EML_Mouse2.26632084
22SPI1_23127762_ChIP-Seq_K562_Human2.25919038
23SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.23879883
24MYC_22102868_ChIP-Seq_BL_Human2.19015980
25MAF_26560356_Chip-Seq_TH1_Human2.17808779
26Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.13160852
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.12971613
28STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.10652171
29TCF7_22412390_ChIP-Seq_EML_Mouse2.07747581
30MYB_26560356_Chip-Seq_TH2_Human1.97536603
31MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.89098757
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.86805715
33STAT4_19710469_ChIP-ChIP_TH1__Mouse1.86406390
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.82901302
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80336860
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.76844838
37LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.74298272
38E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.73991658
39VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73859360
40MYB_26560356_Chip-Seq_TH1_Human1.73303026
41PU_27001747_Chip-Seq_BMDM_Mouse1.71917564
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.68436945
43RUNX_20019798_ChIP-Seq_JUKART_Human1.62736086
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62094685
45KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61795419
46ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.51719340
47KDM2B_26808549_Chip-Seq_SUP-B15_Human1.51377488
48FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.50743857
49GATA2_22383799_ChIP-Seq_G1ME_Mouse1.50737821
50CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.50363419
51PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.49406210
52SMAD_19615063_ChIP-ChIP_OVARY_Human1.48696618
53KDM2B_26808549_Chip-Seq_DND41_Human1.47020208
54IRF8_22096565_ChIP-ChIP_GC-B_Human1.45096949
55GATA1_19941826_ChIP-Seq_K562_Human1.44443599
56RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.43961156
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.40716016
58VDR_24787735_ChIP-Seq_THP-1_Human1.40476926
59IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.40267357
60GATA1_19941827_ChIP-Seq_MEL_Mouse1.40030318
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.36891881
62SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.35165495
63CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.34244800
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.29734890
65TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.29714396
66MAF_26560356_Chip-Seq_TH2_Human1.29291923
67GATA3_27048872_Chip-Seq_THYMUS_Human1.29154498
68LXR_22292898_ChIP-Seq_THP-1_Human1.28180191
69* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26643610
70GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.26174327
71GATA2_19941826_ChIP-Seq_K562_Human1.25973112
72NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.25153487
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24611166
74KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24229919
75SPI1_20517297_ChIP-Seq_HL60_Human1.22687149
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19410543
77RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.15626292
78GATA3_26560356_Chip-Seq_TH2_Human1.15237390
79BCL6_27268052_Chip-Seq_Bcells_Human1.13195305
80E2F4_17652178_ChIP-ChIP_JURKAT_Human1.12840212
81* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11067178
82VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.10627354
83ELF1_17652178_ChIP-ChIP_JURKAT_Human1.10358813
84GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09023621
85* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08922389
86LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08315460
87PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06973526
88BCOR_27268052_Chip-Seq_Bcells_Human1.05597618
89FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.05344273
90STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.04759742
91IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.03495753
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00473438
93EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.98450643
94NCOR1_26117541_ChIP-Seq_K562_Human0.97737874
95KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.97580559
96GATA2_21666600_ChIP-Seq_HMVEC_Human0.95270582
97GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94181585
98TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94003898
99CTCF_27219007_Chip-Seq_ERYTHROID_Human0.93522580
100PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92872117
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92420148
102RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91889985
103* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91415521
104KDM2B_26808549_Chip-Seq_JURKAT_Human0.90962205
105* RACK7_27058665_Chip-Seq_MCF-7_Human0.89376369
106GATA1_22025678_ChIP-Seq_K562_Human0.88229871
107TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.87782063
108RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87266867
109IKZF1_21737484_ChIP-ChIP_HCT116_Human0.83456727
110* SA1_27219007_Chip-Seq_ERYTHROID_Human0.82701173
111E2F1_21310950_ChIP-Seq_MCF-7_Human0.79764106
112PU.1_20513432_ChIP-Seq_Bcells_Mouse0.79065676
113STAT1_20625510_ChIP-Seq_HELA_Human0.78846410

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation6.88254897
2MP0003436_decreased_susceptibility_to5.17342556
3MP0003183_abnormal_peptide_metabolism4.48974528
4MP0009278_abnormal_bone_marrow3.82185587
5* MP0002419_abnormal_innate_immunity3.36282610
6* MP0009785_altered_susceptibility_to3.18940712
7MP0001533_abnormal_skeleton_physiology2.78359779
8MP0005464_abnormal_platelet_physiology2.51231823
9* MP0005025_abnormal_response_to2.50464578
10MP0001851_eye_inflammation2.48303862
11MP0003724_increased_susceptibility_to2.39798377
12MP0000343_altered_response_to2.38580509
13MP0003300_gastrointestinal_ulcer2.36286565
14MP0000465_gastrointestinal_hemorrhage2.33102419
15MP0008260_abnormal_autophagy2.30995737
16MP0002405_respiratory_system_inflammati2.24430876
17MP0005000_abnormal_immune_tolerance2.21412689
18MP0001545_abnormal_hematopoietic_system2.12174763
19MP0005397_hematopoietic_system_phenotyp2.12174763
20MP0002837_dystrophic_cardiac_calcinosis2.09704400
21MP0000685_abnormal_immune_system2.04628448
22* MP0002420_abnormal_adaptive_immunity2.03889011
23* MP0001819_abnormal_immune_cell2.02656776
24MP0002452_abnormal_antigen_presenting1.97512335
25MP0002132_abnormal_respiratory_system1.90289650
26MP0001800_abnormal_humoral_immune1.89760175
27MP0001835_abnormal_antigen_presentation1.81274826
28MP0003763_abnormal_thymus_physiology1.81233461
29MP0001853_heart_inflammation1.80767777
30MP0004808_abnormal_hematopoietic_stem1.79796933
31* MP0001845_abnormal_inflammatory_respons1.77982921
32MP0004883_abnormal_blood_vessel1.76748736
33MP0002148_abnormal_hypersensitivity_rea1.76362452
34MP0001790_abnormal_immune_system1.73026218
35MP0005387_immune_system_phenotype1.73026218
36* MP0002723_abnormal_immune_serum1.71237467
37MP0003075_altered_response_to1.70314868
38MP0003656_abnormal_erythrocyte_physiolo1.67596557
39MP0003566_abnormal_cell_adhesion1.67593347
40MP0005167_abnormal_blood-brain_barrier1.61106411
41MP0002398_abnormal_bone_marrow1.58891100
42MP0000858_altered_metastatic_potential1.54584420
43MP0005451_abnormal_body_composition1.52178120
44MP0003172_abnormal_lysosome_physiology1.52045607
45MP0003866_abnormal_defecation1.51175346
46* MP0000716_abnormal_immune_system1.46910282
47MP0005058_abnormal_lysosome_morphology1.46415511
48MP0000569_abnormal_digit_pigmentation1.45646358
49MP0004381_abnormal_hair_follicle1.44907299
50MP0002277_abnormal_respiratory_mucosa1.41019799
51MP0009333_abnormal_splenocyte_physiolog1.39675239
52MP0002933_joint_inflammation1.38900274
53MP0004947_skin_inflammation1.36656618
54MP0002396_abnormal_hematopoietic_system1.35749885
55MP0009764_decreased_sensitivity_to1.31106830
56MP0005023_abnormal_wound_healing1.29091330
57MP0005164_abnormal_response_to1.28129465
58MP0010155_abnormal_intestine_physiology1.27555443
59* MP0002429_abnormal_blood_cell1.27184607
60MP0001958_emphysema1.26583993
61MP0005076_abnormal_cell_differentiation1.25187376
62MP0002722_abnormal_immune_system1.24700600
63MP0002998_abnormal_bone_remodeling1.22891798
64MP0000689_abnormal_spleen_morphology1.21719072
65MP0002928_abnormal_bile_duct1.15353186
66MP0001873_stomach_inflammation1.15293758
67MP0005390_skeleton_phenotype1.13428839
68MP0003690_abnormal_glial_cell1.09376486
69MP0003191_abnormal_cellular_cholesterol1.09348399
70* MP0008469_abnormal_protein_level1.07838535
71MP0003448_altered_tumor_morphology1.07427352
72MP0005174_abnormal_tail_pigmentation1.03945579
73MP0003828_pulmonary_edema1.03658305
74MP0001663_abnormal_digestive_system1.02823134
75MP0003693_abnormal_embryo_hatching0.99437576
76MP0005671_abnormal_response_to0.94877514
77MP0002282_abnormal_trachea_morphology0.88186745
78MP0005388_respiratory_system_phenotype0.87734898
79MP0002133_abnormal_respiratory_system0.87734898
80MP0005083_abnormal_biliary_tract0.85808916
81MP0002877_abnormal_melanocyte_morpholog0.83196148
82MP0008004_abnormal_stomach_pH0.82541528
83MP0000703_abnormal_thymus_morphology0.82402904
84MP0005166_decreased_susceptibility_to0.81700710
85MP0010307_abnormal_tumor_latency0.81315291
86MP0001986_abnormal_taste_sensitivity0.81132552
87MP0002166_altered_tumor_susceptibility0.79948474
88MP0003279_aneurysm0.79449045
89MP0000604_amyloidosis0.76502997
90MP0004510_myositis0.75699856
91MP0009840_abnormal_foam_cell0.74121376
92MP0006082_CNS_inflammation0.73673992
93MP0000920_abnormal_myelination0.72997733
94MP0003123_paternal_imprinting0.72961448
95MP0003806_abnormal_nucleotide_metabolis0.72634038
96MP0009763_increased_sensitivity_to0.72443439
97MP0003221_abnormal_cardiomyocyte_apopto0.70976304
98MP0002089_abnormal_postnatal_growth/wei0.69829317
99MP0000249_abnormal_blood_vessel0.68772957
100MP0005075_abnormal_melanosome_morpholog0.68465486
101MP0009931_abnormal_skin_appearance0.67099637
102MP0003453_abnormal_keratinocyte_physiol0.66469840
103MP0003329_amyloid_beta_deposits0.65738007
104MP0005377_hearing/vestibular/ear_phenot0.65184120
105MP0003878_abnormal_ear_physiology0.65184120
106MP0009765_abnormal_xenobiotic_induced0.64353084
107MP0005381_digestive/alimentary_phenotyp0.64083844
108MP0005319_abnormal_enzyme/_coenzyme0.63768977
109MP0000490_abnormal_crypts_of0.63351462
110MP0008874_decreased_physiological_sensi0.63279980
111MP0005310_abnormal_salivary_gland0.62292087
112MP0002138_abnormal_hepatobiliary_system0.62232172
113MP0004264_abnormal_extraembryonic_tissu0.62030866
114MP0002796_impaired_skin_barrier0.61591353
115MP0010352_gastrointestinal_tract_polyps0.61226967
116MP0001216_abnormal_epidermal_layer0.60351906
117MP0003045_fibrosis0.57960436
118MP0002006_tumorigenesis0.57199993
119MP0002060_abnormal_skin_morphology0.56836857
120MP0003795_abnormal_bone_structure0.56322728
121MP0000015_abnormal_ear_pigmentation0.54604697
122MP0002019_abnormal_tumor_incidence0.54055730

Predicted human phenotypes

RankGene SetZ-score
1Recurrent gram-negative bacterial infections (HP:0005420)9.89473561
2Recurrent bacterial skin infections (HP:0005406)9.29416857
3Chronic obstructive pulmonary disease (HP:0006510)7.03360703
4Obstructive lung disease (HP:0006536)7.03360703
5Gingivitis (HP:0000230)6.17580062
6Mediastinal lymphadenopathy (HP:0100721)6.03007739
7Abnormality of macrophages (HP:0004311)5.95947024
8Recurrent skin infections (HP:0001581)5.30351000
9Recurrent fungal infections (HP:0002841)5.14077570
10Optic neuritis (HP:0100653)5.08196598
11Retrobulbar optic neuritis (HP:0100654)5.08196598
12Cellulitis (HP:0100658)5.05982833
13Urticaria (HP:0001025)4.82801207
14Stomatitis (HP:0010280)4.34303474
15Spontaneous hematomas (HP:0007420)4.04241308
16Meningitis (HP:0001287)4.00789350
17Keratoconjunctivitis (HP:0001096)3.64417245
18Myositis (HP:0100614)3.59743955
19Episodic fever (HP:0001954)3.31351461
20Abnormal platelet volume (HP:0011876)3.10271885
21Papilledema (HP:0001085)3.02990996
22Osteomyelitis (HP:0002754)2.99031966
23Anorexia (HP:0002039)2.98153404
24Periodontitis (HP:0000704)2.94109834
25Sepsis (HP:0100806)2.92996093
26Recurrent pneumonia (HP:0006532)2.90807040
27Amyloidosis (HP:0011034)2.85116311
28Pulmonary infiltrates (HP:0002113)2.84335692
29Chronic mucocutaneous candidiasis (HP:0002728)2.68336033
30Recurrent cutaneous fungal infections (HP:0011370)2.68336033
31Gangrene (HP:0100758)2.61124772
32Abnormal delayed hypersensitivity skin test (HP:0002963)2.56441465
33Increased mean platelet volume (HP:0011877)2.54222032
34Hypochromic microcytic anemia (HP:0004840)2.52362429
35Metaphyseal cupping (HP:0003021)2.50866391
36Premature loss of primary teeth (HP:0006323)2.50718006
37Pustule (HP:0200039)2.50374645
38Increased IgE level (HP:0003212)2.50361029
39Absent frontal sinuses (HP:0002688)2.49861247
40IgM deficiency (HP:0002850)2.49048987
41Epistaxis (HP:0000421)2.48552207
42Recurrent viral infections (HP:0004429)2.45723807
43Skin ulcer (HP:0200042)2.45077244
44Increased IgM level (HP:0003496)2.42731639
45Prolonged bleeding time (HP:0003010)2.40854186
46T lymphocytopenia (HP:0005403)2.39938934
47Abnormality of T cell number (HP:0011839)2.37762253
48Panhypogammaglobulinemia (HP:0003139)2.37593298
49Vacuolated lymphocytes (HP:0001922)2.37289811
50Interstitial pulmonary disease (HP:0006530)2.36101968
51Hypergammaglobulinemia (HP:0010702)2.36064269
52Petechiae (HP:0000967)2.35247443
53Gingival bleeding (HP:0000225)2.34998389
54Chest pain (HP:0100749)2.34931491
55Recurrent lower respiratory tract infections (HP:0002783)2.32724420
56Difficulty running (HP:0009046)2.31776624
57Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.29694343
58Leukocytosis (HP:0001974)2.28669815
59Abnormality of T cells (HP:0002843)2.27710350
60Orchitis (HP:0100796)2.23426514
61Abnormality of the pleura (HP:0002103)2.21670858
62Increased serum ferritin (HP:0003281)2.20787291
63Colitis (HP:0002583)2.20123142
64Vasculitis (HP:0002633)2.19717771
65Abnormality of the peritoneum (HP:0002585)2.19680151
66Hypermelanotic macule (HP:0001034)2.18814343
67Hemoptysis (HP:0002105)2.18107824
68Cheilitis (HP:0100825)2.16674883
69Malnutrition (HP:0004395)2.13158649
70Elevated erythrocyte sedimentation rate (HP:0003565)2.10386760
71Cutaneous photosensitivity (HP:0000992)2.08145405
72Abnormality of the endocardium (HP:0004306)2.06634646
73Purpura (HP:0000979)2.05327560
74Pulmonary embolism (HP:0002204)2.01844872
75Eczematoid dermatitis (HP:0000976)10.9385269
76Recurrent abscess formation (HP:0002722)10.2618760
77Thickened calvaria (HP:0002684)1.99987820
78Systemic lupus erythematosus (HP:0002725)1.99918989
79Abnormality of iron homeostasis (HP:0011031)1.99378883
80Microcytic anemia (HP:0001935)1.99167154
81Acne (HP:0001061)1.98574681
82Keratitis (HP:0000491)1.98258594
83Increased cerebral lipofuscin (HP:0011813)1.97532084
84Increased density of long bones (HP:0006392)1.97127363
85Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.97101290
86Autoimmune thrombocytopenia (HP:0001973)1.96126625
87Glomerulopathy (HP:0100820)1.95877038
88Hepatosplenomegaly (HP:0001433)1.95568044
89Inflammation of the large intestine (HP:0002037)1.95355829
90Loss of speech (HP:0002371)1.93157065
91Menorrhagia (HP:0000132)1.93116486
92Vertigo (HP:0002321)1.92746777
93Skin rash (HP:0000988)1.92478007
94Hematochezia (HP:0002573)1.91449509
95Peritonitis (HP:0002586)1.90904365
96Chronic otitis media (HP:0000389)1.90510244
97Eosinophilia (HP:0001880)1.89968551
98Verrucae (HP:0200043)1.89548205
99Papilloma (HP:0012740)1.89548205
100Spinal cord lesions (HP:0100561)1.88811844
101Syringomyelia (HP:0003396)1.88811844
102Gastrointestinal inflammation (HP:0004386)1.88312431
103Pyloric stenosis (HP:0002021)1.87287643
104Acute hepatic failure (HP:0006554)1.85135219
105Abnormality of glycolipid metabolism (HP:0010969)1.83432412
106Abnormality of liposaccharide metabolism (HP:0010968)1.83432412
107Abnormality of glycosphingolipid metabolism (HP:0004343)1.83432412
108Spondylolisthesis (HP:0003302)1.81522931
109Abnormal platelet function (HP:0011869)1.81466956
110Impaired platelet aggregation (HP:0003540)1.81466956
111Muscle fiber splitting (HP:0003555)1.79715333
112Viral hepatitis (HP:0006562)1.78951997
113Increased neuronal autofluorescent lipopigment (HP:0002074)1.78796976
114Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.77653983
115Short 4th metacarpal (HP:0010044)1.77653983
116Slow saccadic eye movements (HP:0000514)1.77109660
117Granulocytopenia (HP:0001913)1.73652880
118Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.72513182
119Osteolytic defects of the phalanges of the hand (HP:0009771)1.69911026
120Osteolytic defects of the hand bones (HP:0009699)1.69911026
121Abnormality of cells of the lymphoid lineage (HP:0012140)1.69653938
122Hypochromic anemia (HP:0001931)1.68690103
123Gastrointestinal infarctions (HP:0005244)1.68011219
124Keratoconjunctivitis sicca (HP:0001097)1.67114091
125Abnormal foot bone ossification (HP:0010675)1.66569665
126Lymphopenia (HP:0001888)1.62425538
127Dysostosis multiplex (HP:0000943)1.60214225
128Encephalitis (HP:0002383)1.58243272
129Restrictive lung disease (HP:0002091)1.56854780
130Thoracic kyphosis (HP:0002942)1.55432407
131Abnormality of the frontal sinuses (HP:0002687)1.55214173
132Persistence of primary teeth (HP:0006335)1.55050118
133Ulnar deviation of the wrist (HP:0003049)1.54426078
134Thyroiditis (HP:0100646)1.54064858
135Abnormality of T cell physiology (HP:0011840)1.53127707
136Myelodysplasia (HP:0002863)1.52239382
137Polygenic inheritance (HP:0010982)1.51019785
138Short femoral neck (HP:0100864)1.48468372
139Arterial thrombosis (HP:0004420)1.48393819
140Recurrent sinusitis (HP:0011108)1.48295475
141Ulnar bowing (HP:0003031)1.48285121
142Centrally nucleated skeletal muscle fibers (HP:0003687)1.48270743

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK46.35905614
2EPHB14.17861534
3RIPK43.45140392
4BLK3.22552484
5FES3.03768948
6CSK2.92861840
7GRK62.81223713
8FGR2.76354102
9ERN12.68447435
10TTN2.49925576
11TRPM72.28411002
12TESK22.28297620
13BTK2.25891759
14CLK12.18287449
15STK102.16248418
16PRPF4B2.07763073
17TRIB31.97016279
18MAP4K11.95419820
19MAP3K91.83928796
20MAP2K31.83778407
21TESK11.79543405
22JAK31.74180280
23HCK1.73052427
24MAP3K121.72891210
25PRKG21.71768477
26TEC1.53459251
27ALK1.52511295
28LRRK21.48331841
29PAK41.45758118
30ERBB31.44416603
31PTK61.37613190
32SIK31.35580003
33ZAP701.33363906
34MAP3K131.19737405
35PKN21.16698645
36MARK21.09992378
37MAPK41.08041882
38SYK1.04485834
39PRKD21.04244149
40KSR21.02977035
41MAP2K61.02619294
42NEK20.99969638
43IRAK10.97185312
44PTK20.96792400
45MAP2K40.96593642
46MAP3K110.95976303
47TAOK20.93881508
48RIPK10.93874984
49SIK20.93737121
50MAP3K20.92653071
51LIMK10.89722234
52IRAK20.87579172
53PTK2B0.87073504
54KDR0.86523132
55LYN0.80050594
56ITK0.79750871
57TAOK10.78891446
58CSF1R0.78645021
59CDK190.78643926
60TYK20.76754309
61BMPR20.75886233
62IKBKB0.75231980
63MAP3K50.72991128
64SMG10.71117741
65PIM10.70771746
66MAP3K70.70740658
67MAP3K60.69144514
68MAP3K80.68920348
69TNK20.68279956
70MARK30.68155042
71FYN0.67758422
72LCK0.67381386
73TGFBR20.66558489
74RPS6KA20.64461842
75MAP3K140.63603078
76WEE10.63122565
77TBK10.58800411
78RET0.58704566
79DYRK1B0.57458344
80PRKCD0.57057201
81CDC42BPA0.56146423
82MAP3K10.55753043
83MAPKAPK20.54126489
84YES10.53900488
85RPS6KL10.53815415
86RPS6KC10.53815415
87MAPK120.53563232
88IRAK30.52488998
89MATK0.51866863
90STK40.51681469
91SIK10.51437834
92DMPK0.50677591
93RPS6KA60.50442387
94JAK20.50058719
95PRKCH0.48772647
96SGK30.47067600
97RAF10.46827645
98MAPK70.46619952
99PDPK10.46150284
100KSR10.45658341
101HIPK20.44000082
102FGFR40.43865828
103PDK10.41913374
104STK380.41394496
105MAPK110.41037236
106STK110.40497509
107EGFR0.39242884
108MAP3K30.38329890
109DAPK20.37702493
110PRKCQ0.37566398
111CAMK1G0.37554412
112CAMK1D0.36213034
113PIK3CG0.31323851
114ABL10.31283769
115STK240.30482296
116PRKAA20.29819525
117BRSK20.29390486
118KIT0.29330047
119JAK10.28704318
120TXK0.28680372
121RPS6KA10.27890729
122PRKD10.27444554
123GRK70.26935157
124BMX0.25631184
125EPHA30.24595419
126FGFR30.23947199
127IKBKE0.23336709
128TAOK30.22656423
129SRC0.22465596
130PRKG10.21909015
131ILK0.21888951
132CDK60.21646418
133PRKACG0.21475313
134PRKCZ0.18859530

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051404.52490854
2Asthma_Homo sapiens_hsa053103.64119040
3Staphylococcus aureus infection_Homo sapiens_hsa051503.62404128
4Leukocyte transendothelial migration_Homo sapiens_hsa046703.23277587
5Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.11041651
6Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.96207704
7Osteoclast differentiation_Homo sapiens_hsa043802.68517710
8Chemokine signaling pathway_Homo sapiens_hsa040622.09751434
9Tuberculosis_Homo sapiens_hsa051522.05343215
10Shigellosis_Homo sapiens_hsa051312.03879041
11Graft-versus-host disease_Homo sapiens_hsa053321.99637418
12Allograft rejection_Homo sapiens_hsa053301.95691424
13Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.90942445
14Pentose phosphate pathway_Homo sapiens_hsa000301.87506905
15B cell receptor signaling pathway_Homo sapiens_hsa046621.84660707
16Autoimmune thyroid disease_Homo sapiens_hsa053201.82199217
17Pertussis_Homo sapiens_hsa051331.80811594
18Platelet activation_Homo sapiens_hsa046111.72086286
19Primary immunodeficiency_Homo sapiens_hsa053401.70156428
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.62894671
21Phagosome_Homo sapiens_hsa041451.61814523
22Hematopoietic cell lineage_Homo sapiens_hsa046401.58938285
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.55300122
24VEGF signaling pathway_Homo sapiens_hsa043701.50201914
25Salmonella infection_Homo sapiens_hsa051321.50034329
26Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.48037870
27Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.42476450
28Antigen processing and presentation_Homo sapiens_hsa046121.42374865
29Type I diabetes mellitus_Homo sapiens_hsa049401.42359858
30Neurotrophin signaling pathway_Homo sapiens_hsa047221.40796158
31Caffeine metabolism_Homo sapiens_hsa002321.37047433
32Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.33625621
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29273745
34Legionellosis_Homo sapiens_hsa051341.29196080
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.28063389
36Toxoplasmosis_Homo sapiens_hsa051451.26027582
37Pancreatic cancer_Homo sapiens_hsa052121.15309237
38NF-kappa B signaling pathway_Homo sapiens_hsa040641.08003918
39Hepatitis B_Homo sapiens_hsa051611.04315430
40Acute myeloid leukemia_Homo sapiens_hsa052211.01924889
41Insulin resistance_Homo sapiens_hsa049311.01357295
42Non-small cell lung cancer_Homo sapiens_hsa052231.01299837
43TNF signaling pathway_Homo sapiens_hsa046681.01256820
44Amoebiasis_Homo sapiens_hsa051460.96322863
45Chronic myeloid leukemia_Homo sapiens_hsa052200.94603507
46Sphingolipid signaling pathway_Homo sapiens_hsa040710.93693212
47RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.92558817
48Starch and sucrose metabolism_Homo sapiens_hsa005000.92321584
49Jak-STAT signaling pathway_Homo sapiens_hsa046300.92092510
50Other glycan degradation_Homo sapiens_hsa005110.90049957
51Malaria_Homo sapiens_hsa051440.89088019
52Regulation of actin cytoskeleton_Homo sapiens_hsa048100.89012760
53Viral myocarditis_Homo sapiens_hsa054160.88958780
54Bladder cancer_Homo sapiens_hsa052190.87914051
55Carbohydrate digestion and absorption_Homo sapiens_hsa049730.86063185
56AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.84998906
57Rheumatoid arthritis_Homo sapiens_hsa053230.82818629
58Histidine metabolism_Homo sapiens_hsa003400.82811001
59Glycosaminoglycan degradation_Homo sapiens_hsa005310.82601319
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.82209245
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81833161
62Apoptosis_Homo sapiens_hsa042100.77833805
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76734028
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76311867
65Influenza A_Homo sapiens_hsa051640.75476438
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.75415832
67Measles_Homo sapiens_hsa051620.74874488
68Endocytosis_Homo sapiens_hsa041440.73910402
69Rap1 signaling pathway_Homo sapiens_hsa040150.73212727
70Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72584012
71SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71727490
72Hepatitis C_Homo sapiens_hsa051600.69914470
73GnRH signaling pathway_Homo sapiens_hsa049120.69601736
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.67640046
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66916781
76Notch signaling pathway_Homo sapiens_hsa043300.66823095
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.66514406
78Phospholipase D signaling pathway_Homo sapiens_hsa040720.66240571
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.64278237
80T cell receptor signaling pathway_Homo sapiens_hsa046600.63818880
81ABC transporters_Homo sapiens_hsa020100.60899893
82Estrogen signaling pathway_Homo sapiens_hsa049150.60552926
83Choline metabolism in cancer_Homo sapiens_hsa052310.59220585
84Proteoglycans in cancer_Homo sapiens_hsa052050.58852069
85Endometrial cancer_Homo sapiens_hsa052130.58354158
86Glioma_Homo sapiens_hsa052140.56936501
87Olfactory transduction_Homo sapiens_hsa047400.56903894
88Glutathione metabolism_Homo sapiens_hsa004800.56589938
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56374432
90Lysosome_Homo sapiens_hsa041420.55238016
91Glycerolipid metabolism_Homo sapiens_hsa005610.54841838
92African trypanosomiasis_Homo sapiens_hsa051430.54517993
93Regulation of autophagy_Homo sapiens_hsa041400.54208760
94Type II diabetes mellitus_Homo sapiens_hsa049300.53302817
95Herpes simplex infection_Homo sapiens_hsa051680.52882455
96Insulin signaling pathway_Homo sapiens_hsa049100.51969495
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.51702842
98MAPK signaling pathway_Homo sapiens_hsa040100.50339779
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49885275
100HIF-1 signaling pathway_Homo sapiens_hsa040660.48539715
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.48425623
102FoxO signaling pathway_Homo sapiens_hsa040680.47931690
103Inositol phosphate metabolism_Homo sapiens_hsa005620.47466764
104Dorso-ventral axis formation_Homo sapiens_hsa043200.46548014
105mTOR signaling pathway_Homo sapiens_hsa041500.46504996
106Focal adhesion_Homo sapiens_hsa045100.46304301
107Complement and coagulation cascades_Homo sapiens_hsa046100.44786576
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44059237
109HTLV-I infection_Homo sapiens_hsa051660.43984991
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43505837
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43404370
112Epstein-Barr virus infection_Homo sapiens_hsa051690.42847517
113Cell cycle_Homo sapiens_hsa041100.42263983
114Viral carcinogenesis_Homo sapiens_hsa052030.42053108
115Galactose metabolism_Homo sapiens_hsa000520.41628045
116Prolactin signaling pathway_Homo sapiens_hsa049170.41626334
117MicroRNAs in cancer_Homo sapiens_hsa052060.40266922
118Renal cell carcinoma_Homo sapiens_hsa052110.39870828
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39732817
120Adherens junction_Homo sapiens_hsa045200.37312379
121Fructose and mannose metabolism_Homo sapiens_hsa000510.35991831
122Salivary secretion_Homo sapiens_hsa049700.33865623
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32075272
124Colorectal cancer_Homo sapiens_hsa052100.31521511

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »