SAC3D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.41210429
2pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)5.96926347
3CTP metabolic process (GO:0046036)5.55005072
4CTP biosynthetic process (GO:0006241)5.55005072
5pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.54695498
6ribosomal small subunit assembly (GO:0000028)5.24961973
7pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.17847081
8maturation of SSU-rRNA (GO:0030490)5.04222162
9viral transcription (GO:0019083)4.99372314
10pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)4.94891242
11translational termination (GO:0006415)4.89375206
12UTP biosynthetic process (GO:0006228)4.79198702
13ribosomal small subunit biogenesis (GO:0042274)4.79132996
14pyrimidine nucleoside monophosphate metabolic process (GO:0009129)4.74919639
15DNA strand elongation involved in DNA replication (GO:0006271)4.73357426
16GTP biosynthetic process (GO:0006183)4.73345866
17telomere maintenance via semi-conservative replication (GO:0032201)4.52653845
18guanosine-containing compound biosynthetic process (GO:1901070)4.48458830
19DNA strand elongation (GO:0022616)4.48156686
20translational elongation (GO:0006414)4.47155584
21DNA replication initiation (GO:0006270)4.44051415
22formation of translation preinitiation complex (GO:0001731)4.43172895
23nucleotide salvage (GO:0043173)4.39495246
24UTP metabolic process (GO:0046051)4.34582764
252-deoxyribonucleotide biosynthetic process (GO:0009265)4.32716999
26deoxyribose phosphate biosynthetic process (GO:0046385)4.32716999
27SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.28442020
28DNA replication checkpoint (GO:0000076)4.28135867
29pyrimidine nucleotide biosynthetic process (GO:0006221)4.25770519
30ribonucleoprotein complex biogenesis (GO:0022613)4.23799485
31translational initiation (GO:0006413)4.23136277
32pseudouridine synthesis (GO:0001522)4.18221800
33cotranslational protein targeting to membrane (GO:0006613)4.15648545
34protein targeting to ER (GO:0045047)4.15142602
35nucleobase biosynthetic process (GO:0046112)4.14771788
36ribosome biogenesis (GO:0042254)4.14261740
37negative regulation of mRNA processing (GO:0050686)4.13497247
38regulation of mammary gland epithelial cell proliferation (GO:0033599)4.13396053
39ribosomal large subunit biogenesis (GO:0042273)4.11804985
40pyrimidine deoxyribonucleotide metabolic process (GO:0009219)4.07968641
41nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.05991048
42nucleoside salvage (GO:0043174)4.03211755
43pentose metabolic process (GO:0019321)3.98486855
44pyrimidine nucleoside salvage (GO:0043097)3.97894679
45pyrimidine-containing compound salvage (GO:0008655)3.97894679
46folic acid-containing compound biosynthetic process (GO:0009396)3.96773563
47pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.95563635
48purine nucleobase biosynthetic process (GO:0009113)3.94985555
49protein localization to endoplasmic reticulum (GO:0070972)3.93511462
50establishment of protein localization to endoplasmic reticulum (GO:0072599)3.92948055
51deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.90865679
52DNA unwinding involved in DNA replication (GO:0006268)3.90284438
53cellular protein complex disassembly (GO:0043624)3.89670409
54mitotic chromosome condensation (GO:0007076)3.88465056
55proteasome assembly (GO:0043248)3.85557289
56viral life cycle (GO:0019058)3.84603038
57telomere maintenance via recombination (GO:0000722)3.84565620
58pyrimidine nucleoside biosynthetic process (GO:0046134)3.80914566
59deoxyribonucleotide biosynthetic process (GO:0009263)3.80095239
60rRNA processing (GO:0006364)3.74653282
61spliceosomal snRNP assembly (GO:0000387)3.74611872
62translesion synthesis (GO:0019985)3.74448478
63pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.72594873
64heterochromatin organization (GO:0070828)3.63115283
65rRNA metabolic process (GO:0016072)3.61115766
66translation (GO:0006412)3.58610116
67protein localization to kinetochore (GO:0034501)3.56703115
68protein complex disassembly (GO:0043241)3.54474838
69rRNA modification (GO:0000154)3.54036128
70mitotic metaphase plate congression (GO:0007080)3.52408258
71telomere maintenance via telomere lengthening (GO:0010833)3.52324465
72mitotic recombination (GO:0006312)3.51893870
73DNA replication-dependent nucleosome assembly (GO:0006335)3.50908555
74DNA replication-dependent nucleosome organization (GO:0034723)3.50908555
75pyrimidine nucleotide metabolic process (GO:0006220)3.47452489
76deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.46605164
77DNA synthesis involved in DNA repair (GO:0000731)3.46463075
78grooming behavior (GO:0007625)3.45902142
79cellular component biogenesis (GO:0044085)3.45633690
80pyrimidine-containing compound biosynthetic process (GO:0072528)3.44865093
81mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.42783076
82ribosome assembly (GO:0042255)3.42576685
83negative regulation of mRNA metabolic process (GO:1903312)3.42256247
84pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)3.40772247
85UMP metabolic process (GO:0046049)3.40772247
86pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)3.40772247
87UMP biosynthetic process (GO:0006222)3.40772247
88macromolecular complex disassembly (GO:0032984)3.38321254
89regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.38274400
90proline biosynthetic process (GO:0006561)3.37347782
91transcription elongation from RNA polymerase III promoter (GO:0006385)3.34511891
92termination of RNA polymerase III transcription (GO:0006386)3.34511891
93chaperone-mediated protein transport (GO:0072321)3.34188869
94pyrimidine ribonucleotide metabolic process (GO:0009218)3.31161083
95CENP-A containing nucleosome assembly (GO:0034080)3.30620956
96nucleotide-excision repair, DNA gap filling (GO:0006297)3.30041772
97chromatin remodeling at centromere (GO:0031055)3.29900221
98folic acid metabolic process (GO:0046655)3.29003342
99mitochondrial respiratory chain complex assembly (GO:0033108)3.27579948
100protein complex biogenesis (GO:0070271)3.25879652
101negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.25190363
102pentose-phosphate shunt (GO:0006098)3.24822967
103energy coupled proton transport, down electrochemical gradient (GO:0015985)3.20896354
104ATP synthesis coupled proton transport (GO:0015986)3.20896354
105pteridine-containing compound biosynthetic process (GO:0042559)3.19939845
106oxidative phosphorylation (GO:0006119)3.19619985
107protein localization to chromosome, centromeric region (GO:0071459)3.19585433
108nuclear-transcribed mRNA catabolic process (GO:0000956)3.19339019
109mitotic nuclear envelope disassembly (GO:0007077)3.19085639
110protein targeting to membrane (GO:0006612)3.17627118
111anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.16563505
112ribonucleoside triphosphate biosynthetic process (GO:0009201)3.14785450
113base-excision repair (GO:0006284)3.14309707
114pyrimidine nucleotide catabolic process (GO:0006244)3.12831778
115transcription-coupled nucleotide-excision repair (GO:0006283)3.12080431
116regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.10609155
117spliceosomal complex assembly (GO:0000245)3.09849803
118DNA replication-independent nucleosome organization (GO:0034724)3.09013062
119DNA replication-independent nucleosome assembly (GO:0006336)3.09013062
120L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.08629211
121protein targeting to mitochondrion (GO:0006626)3.08130810
122transcription from mitochondrial promoter (GO:0006390)3.06493948
123positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.04606647
124negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.03508764
125negative regulation of ligase activity (GO:0051352)3.03508764
126protein maturation by protein folding (GO:0022417)3.03082095
127exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.02832785
128IMP biosynthetic process (GO:0006188)3.02374177
129mRNA catabolic process (GO:0006402)3.02140158
130NADH dehydrogenase complex assembly (GO:0010257)3.01527136
131RNA catabolic process (GO:0006401)2.97329338
132regulation of protein heterodimerization activity (GO:0043497)2.96947268
133protein deneddylation (GO:0000338)2.95510812
134regulation of mitochondrial translation (GO:0070129)2.94544849
135G1/S transition of mitotic cell cycle (GO:0000082)2.93787297
136cell cycle G1/S phase transition (GO:0044843)2.93787297
137negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.92211461
138cullin deneddylation (GO:0010388)2.91893277
139nuclear envelope disassembly (GO:0051081)2.91510518
140membrane disassembly (GO:0030397)2.91510518
141kinetochore assembly (GO:0051382)2.88615531
142nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.88540693
143metaphase plate congression (GO:0051310)2.88285060
144negative regulation of RNA splicing (GO:0033119)2.87915496
145pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.87910682
146nucleobase-containing small molecule interconversion (GO:0015949)2.87275973
147DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.86932714
148mitotic sister chromatid segregation (GO:0000070)2.85737300
149establishment of integrated proviral latency (GO:0075713)2.84911607
150intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.83492090
151signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.83492090
152ncRNA processing (GO:0034470)2.83438510
153pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.83411354
154signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.81493931
155signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.81493931
156signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.81493931
157regulation of nuclear cell cycle DNA replication (GO:0033262)2.80237102

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.68147772
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.34782558
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.17864037
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.13178867
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.11760185
6* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.07064266
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.01092137
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.97267565
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.94232042
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.91107779
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.91050158
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.90057467
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80792891
14* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.71174813
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.70379098
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.60839056
17XRN2_22483619_ChIP-Seq_HELA_Human2.54516406
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.54367311
19* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.28870212
20VDR_23849224_ChIP-Seq_CD4+_Human2.24050223
21* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.15278511
22DCP1A_22483619_ChIP-Seq_HELA_Human2.13794567
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12399752
24GABP_19822575_ChIP-Seq_HepG2_Human2.01100668
25THAP11_20581084_ChIP-Seq_MESCs_Mouse1.97190374
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.95767009
27FOXP3_21729870_ChIP-Seq_TREG_Human1.93868620
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.93676845
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92794099
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.91843958
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.91490967
32* LXR_22292898_ChIP-Seq_THP-1_Human1.89234896
33TTF2_22483619_ChIP-Seq_HELA_Human1.88103801
34PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.87903156
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.86720036
36TET1_21451524_ChIP-Seq_MESCs_Mouse1.74270177
37SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.74177534
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73350922
39MYC_22102868_ChIP-Seq_BL_Human1.69942827
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68626464
41* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.67439641
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67068888
43* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64852356
44* E2F1_21310950_ChIP-Seq_MCF-7_Human1.62784624
45CIITA_25753668_ChIP-Seq_RAJI_Human1.61147491
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55896936
47* SRF_21415370_ChIP-Seq_HL-1_Mouse1.54938629
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.54612712
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.54135999
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.51967087
51AR_21909140_ChIP-Seq_LNCAP_Human1.51331972
52P68_20966046_ChIP-Seq_HELA_Human1.47339119
53CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.44820926
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.44445057
55VDR_21846776_ChIP-Seq_THP-1_Human1.44164789
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.43657278
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43623870
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.42944443
59E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42262536
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.38597511
61KDM5A_27292631_Chip-Seq_BREAST_Human1.37106440
62* RACK7_27058665_Chip-Seq_MCF-7_Human1.36975161
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35970017
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.35072161
65HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34903212
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.34798463
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33068763
68ELK1_19687146_ChIP-ChIP_HELA_Human1.31348563
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.30153387
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29129154
71PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28688777
72YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22788429
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.22349086
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.22275375
75* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.20635790
76ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20418022
77TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19731795
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19459730
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.19258377
80TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.17060548
81ELF1_20517297_ChIP-Seq_JURKAT_Human1.16289126
82* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.16005195
83* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14547326
84SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.14168879
85TFEB_21752829_ChIP-Seq_HELA_Human1.12168984
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11607961
87SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11106827
88SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.09518772
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09208039
90* SA1_27219007_Chip-Seq_ERYTHROID_Human1.09203304
91SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.08465007
92BCL6_27268052_Chip-Seq_Bcells_Human1.08433441
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06934252
94TBX5_21415370_ChIP-Seq_HL-1_Mouse1.06543605
95THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05936546
96CTCF_26484167_Chip-Seq_Bcells_Mouse1.05602966
97ELK1_22589737_ChIP-Seq_MCF10A_Human1.04787713
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02914003
99CTCF_21964334_Chip-Seq_Bcells_Human1.02838068
100SRY_22984422_ChIP-ChIP_TESTIS_Rat1.02318026
101* TP53_22127205_ChIP-Seq_IMR90_Human1.01808918
102CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01446410
103NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.00895925
104CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00616646
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00549385
106SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00274534
107* SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.98779009
108* SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98261971
109KDM2B_26808549_Chip-Seq_DND41_Human0.97444127
110SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96376683
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.96132904
112ERG_21242973_ChIP-ChIP_JURKAT_Human0.94395262
113ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.94003082
114SPI1_23547873_ChIP-Seq_NB4_Human0.93976764
115BCOR_27268052_Chip-Seq_Bcells_Human0.93286837
116CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92535225
117CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92528430
118MYC_18940864_ChIP-ChIP_HL60_Human0.89703775
119FOXP1_21924763_ChIP-Seq_HESCs_Human0.88820647
120TP63_19390658_ChIP-ChIP_HaCaT_Human0.86276668
121YY1_22570637_ChIP-Seq_MALME-3M_Human0.85318903
122* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.84676861
123ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.83268782
124PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81456695
125* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80422686
126CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.80237020
127ZNF263_19887448_ChIP-Seq_K562_Human0.79717959

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.64547913
2MP0004957_abnormal_blastocyst_morpholog4.75255539
3MP0003111_abnormal_nucleus_morphology4.40339769
4MP0010094_abnormal_chromosome_stability4.18651471
5MP0002234_abnormal_pharynx_morphology4.11363634
6MP0003077_abnormal_cell_cycle3.93114839
7MP0008057_abnormal_DNA_replication3.90473634
8MP0008058_abnormal_DNA_repair3.05306422
9MP0008007_abnormal_cellular_replicative2.96298190
10MP0008932_abnormal_embryonic_tissue2.91124511
11MP0002396_abnormal_hematopoietic_system2.48635787
12MP0001346_abnormal_lacrimal_gland2.47978248
13MP0000490_abnormal_crypts_of2.46202923
14MP0004858_abnormal_nervous_system2.34460598
15MP0004185_abnormal_adipocyte_glucose2.31316692
16MP0000350_abnormal_cell_proliferation2.29131906
17MP0003123_paternal_imprinting2.16862781
18MP0001730_embryonic_growth_arrest2.16389863
19MP0005451_abnormal_body_composition2.05016621
20MP0010352_gastrointestinal_tract_polyps1.97199015
21MP0003786_premature_aging1.92448515
22MP0003806_abnormal_nucleotide_metabolis1.92101476
23MP0009333_abnormal_splenocyte_physiolog1.89269626
24MP0000049_abnormal_middle_ear1.88109918
25MP0001545_abnormal_hematopoietic_system1.74399491
26MP0005397_hematopoietic_system_phenotyp1.74399491
27MP0000313_abnormal_cell_death1.73031662
28MP0004233_abnormal_muscle_weight1.72911457
29MP0001697_abnormal_embryo_size1.68326770
30MP0005501_abnormal_skin_physiology1.68007605
31MP0005379_endocrine/exocrine_gland_phen1.65468497
32MP0002249_abnormal_larynx_morphology1.65138018
33MP0002080_prenatal_lethality1.63577554
34MP0009379_abnormal_foot_pigmentation1.63213433
35MP0005076_abnormal_cell_differentiation1.62738318
36MP0003718_maternal_effect1.59985528
37MP0005623_abnormal_meninges_morphology1.59814435
38MP0005380_embryogenesis_phenotype1.57806243
39MP0001672_abnormal_embryogenesis/_devel1.57806243
40MP0002132_abnormal_respiratory_system1.55546769
41MP0002019_abnormal_tumor_incidence1.54265186
42MP0010030_abnormal_orbit_morphology1.48669096
43MP0006036_abnormal_mitochondrial_physio1.46576981
44MP0003984_embryonic_growth_retardation1.46527284
45MP0000358_abnormal_cell_content/1.45960873
46MP0009053_abnormal_anal_canal1.45304349
47MP0004808_abnormal_hematopoietic_stem1.40819504
48MP0003705_abnormal_hypodermis_morpholog1.40664485
49MP0010307_abnormal_tumor_latency1.40325200
50MP0002088_abnormal_embryonic_growth/wei1.40149009
51MP0002085_abnormal_embryonic_tissue1.40050603
52MP0009278_abnormal_bone_marrow1.39838067
53MP0003763_abnormal_thymus_physiology1.38380886
54MP0006035_abnormal_mitochondrial_morpho1.38358270
55MP0006292_abnormal_olfactory_placode1.36220346
56MP0000681_abnormal_thyroid_gland1.28976059
57MP0003186_abnormal_redox_activity1.27998219
58MP0002653_abnormal_ependyma_morphology1.24629354
59* MP0002398_abnormal_bone_marrow1.23575756
60MP0002086_abnormal_extraembryonic_tissu1.22277341
61MP0003656_abnormal_erythrocyte_physiolo1.20766094
62MP0000537_abnormal_urethra_morphology1.19745355
63MP0005075_abnormal_melanosome_morpholog1.19640759
64* MP0002722_abnormal_immune_system1.19534840
65MP0001881_abnormal_mammary_gland1.18241146
66MP0002084_abnormal_developmental_patter1.16747064
67MP0001348_abnormal_lacrimal_gland1.14679817
68* MP0000703_abnormal_thymus_morphology1.14058749
69MP0004510_myositis1.13075919
70* MP0000689_abnormal_spleen_morphology1.12393278
71MP0000566_synostosis1.09860834
72MP0002877_abnormal_melanocyte_morpholog1.09502641
73MP0001293_anophthalmia1.09203005
74MP0003942_abnormal_urinary_system1.08865010
75MP0005266_abnormal_metabolism1.07993320
76MP0000858_altered_metastatic_potential1.07726884
77MP0005670_abnormal_white_adipose1.07228349
78MP0009672_abnormal_birth_weight1.04650417
79* MP0002429_abnormal_blood_cell1.01924432
80MP0008877_abnormal_DNA_methylation1.01767038
81MP0003567_abnormal_fetal_cardiomyocyte1.00770964
82MP0001661_extended_life_span1.00134637
83MP0003315_abnormal_perineum_morphology1.00112487
84MP0002210_abnormal_sex_determination0.98795023
85MP0009250_abnormal_appendicular_skeleto0.98706751
86MP0001145_abnormal_male_reproductive0.98517961
87MP0003221_abnormal_cardiomyocyte_apopto0.94120328
88MP0005330_cardiomyopathy0.93850988
89MP0000678_abnormal_parathyroid_gland0.93299775
90MP0000003_abnormal_adipose_tissue0.92393775
91MP0005220_abnormal_exocrine_pancreas0.91289902
92MP0005375_adipose_tissue_phenotype0.89750946
93MP0002822_catalepsy0.88979230
94MP0004197_abnormal_fetal_growth/weight/0.88778526
95MP0005384_cellular_phenotype0.88559910
96MP0002697_abnormal_eye_size0.88296866
97MP0003890_abnormal_embryonic-extraembry0.88296768
98MP0005666_abnormal_adipose_tissue0.87820626
99MP0003119_abnormal_digestive_system0.86311144
100MP0002160_abnormal_reproductive_system0.85704041
101MP0000685_abnormal_immune_system0.83735345
102* MP0000716_abnormal_immune_system0.83706464
103MP0005360_urolithiasis0.83554484
104MP0002796_impaired_skin_barrier0.83422646
105MP0001929_abnormal_gametogenesis0.82362705
106MP0001853_heart_inflammation0.81230396
107MP0000613_abnormal_salivary_gland0.81052514
108MP0002163_abnormal_gland_morphology0.80707271
109MP0005621_abnormal_cell_physiology0.79104668
110MP0008789_abnormal_olfactory_epithelium0.78624703
111MP0000477_abnormal_intestine_morphology0.78083253
112MP0001919_abnormal_reproductive_system0.76966707
113MP0002092_abnormal_eye_morphology0.75935208
114MP0000750_abnormal_muscle_regeneration0.75864483
115MP0000653_abnormal_sex_gland0.75154789
116MP0003453_abnormal_keratinocyte_physiol0.74713576
117MP0001529_abnormal_vocalization0.74592293
118MP0002111_abnormal_tail_morphology0.74134423
119MP0004133_heterotaxia0.72836627
120MP0001188_hyperpigmentation0.71510578
121MP0004145_abnormal_muscle_electrophysio0.70584516
122MP0000759_abnormal_skeletal_muscle0.68719763
123MP0002405_respiratory_system_inflammati0.68160292
124MP0003385_abnormal_body_wall0.67478323
125MP0009384_cardiac_valve_regurgitation0.66911212
126MP0000467_abnormal_esophagus_morphology0.66348838
127MP0008770_decreased_survivor_rate0.66285774
128MP0006054_spinal_hemorrhage0.66096084
129MP0002114_abnormal_axial_skeleton0.65745236
130MP0002970_abnormal_white_adipose0.65660144
131MP0000534_abnormal_ureter_morphology0.64450611
132MP0000627_abnormal_mammary_gland0.63133073
133MP0005499_abnormal_olfactory_system0.62673128
134MP0005394_taste/olfaction_phenotype0.62673128
135MP0002269_muscular_atrophy0.61365285
136MP0004264_abnormal_extraembryonic_tissu0.59468830
137MP0002932_abnormal_joint_morphology0.58527595
138MP0005671_abnormal_response_to0.56810029
139MP0004147_increased_porphyrin_level0.56211016
140* MP0002420_abnormal_adaptive_immunity0.55395108
141* MP0001819_abnormal_immune_cell0.54705674
142MP0009840_abnormal_foam_cell0.54297758
143MP0001835_abnormal_antigen_presentation0.52679003
144MP0001119_abnormal_female_reproductive0.52117647
145MP0002751_abnormal_autonomic_nervous0.51882034
146MP0005023_abnormal_wound_healing0.51705832
147MP0005389_reproductive_system_phenotype0.51388953
148MP0001873_stomach_inflammation0.51269555
149MP0002102_abnormal_ear_morphology0.51121823
150MP0001800_abnormal_humoral_immune0.50152511

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.07942984
2Abnormal number of erythroid precursors (HP:0012131)6.00687711
3Reticulocytopenia (HP:0001896)4.86053233
4Achilles tendon contracture (HP:0001771)4.71036006
5Birth length less than 3rd percentile (HP:0003561)4.45111277
6Aplastic anemia (HP:0001915)4.34508335
7Abnormality of the Achilles tendon (HP:0005109)4.15098408
8Broad distal phalanx of finger (HP:0009836)3.91180479
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.78325385
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.78325385
11Oral leukoplakia (HP:0002745)3.75995658
12Breast hypoplasia (HP:0003187)3.75829422
13Microretrognathia (HP:0000308)3.69001547
14Macrocytic anemia (HP:0001972)3.64298784
15Pallor (HP:0000980)3.63969289
16Aplasia/Hypoplasia of the sacrum (HP:0008517)3.45061796
17Multiple enchondromatosis (HP:0005701)3.39772773
18Trismus (HP:0000211)3.31085369
19Progressive muscle weakness (HP:0003323)3.19546721
20Cerebral hypomyelination (HP:0006808)3.12767126
21Rough bone trabeculation (HP:0100670)3.12700012
22Selective tooth agenesis (HP:0001592)3.10167772
23Acute encephalopathy (HP:0006846)3.03003836
24Hepatocellular necrosis (HP:0001404)3.02356769
25Patellar aplasia (HP:0006443)2.93529391
26Increased serum lactate (HP:0002151)2.91073769
27Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.90858922
28Carpal bone hypoplasia (HP:0001498)2.85688898
29Degeneration of anterior horn cells (HP:0002398)2.85063095
30Abnormality of the anterior horn cell (HP:0006802)2.85063095
31Thrombocytosis (HP:0001894)2.78118079
32Aplasia/Hypoplasia of the patella (HP:0006498)2.76617437
33Opisthotonus (HP:0002179)2.74737045
34Colon cancer (HP:0003003)2.74678046
35Hyperacusis (HP:0010780)2.72302590
36Absent thumb (HP:0009777)2.72254369
37Type I transferrin isoform profile (HP:0003642)2.69445969
38Abnormality of the heme biosynthetic pathway (HP:0010472)2.69251112
39Hepatic necrosis (HP:0002605)2.65664162
40Testicular atrophy (HP:0000029)2.64233623
4111 pairs of ribs (HP:0000878)2.59743282
42Mitochondrial inheritance (HP:0001427)2.58456966
43Exertional dyspnea (HP:0002875)2.50832255
44Meckel diverticulum (HP:0002245)2.50600254
45Increased CSF lactate (HP:0002490)2.50282693
46Ependymoma (HP:0002888)2.49059180
47Renal Fanconi syndrome (HP:0001994)2.48844048
48Abnormality of the umbilical cord (HP:0010881)2.48275083
49Abnormal number of incisors (HP:0011064)2.46280600
50Double outlet right ventricle (HP:0001719)2.46198592
51Congenital malformation of the right heart (HP:0011723)2.46198592
52Premature ovarian failure (HP:0008209)2.46090221
53Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.45118554
54Abnormality of the ileum (HP:0001549)2.43802017
55Insomnia (HP:0100785)2.43012496
56Progressive macrocephaly (HP:0004481)2.42845334
57Increased hepatocellular lipid droplets (HP:0006565)2.42354370
58Progressive microcephaly (HP:0000253)2.38512914
59Abnormality of the preputium (HP:0100587)2.37571734
60Abnormality of reticulocytes (HP:0004312)2.34545432
61Basal cell carcinoma (HP:0002671)2.32115395
62Rectal prolapse (HP:0002035)2.31216027
63Premature graying of hair (HP:0002216)2.30969967
64Aplasia/Hypoplasia of the uvula (HP:0010293)2.30951323
65Cerebral edema (HP:0002181)2.28962385
66Secondary amenorrhea (HP:0000869)2.28640955
67Rhabdomyosarcoma (HP:0002859)2.27100052
68Patent foramen ovale (HP:0001655)2.26930844
69Ragged-red muscle fibers (HP:0003200)2.26244411
70Chromsome breakage (HP:0040012)2.25676139
71Chromosomal breakage induced by crosslinking agents (HP:0003221)2.25577109
72Lipid accumulation in hepatocytes (HP:0006561)2.24886823
73Myelodysplasia (HP:0002863)2.23737090
74Slender long bone (HP:0003100)2.23327706
75Medulloblastoma (HP:0002885)2.23158119
76Increased intramyocellular lipid droplets (HP:0012240)2.22890777
77Muscle fiber atrophy (HP:0100295)2.22201829
78Neoplasm of the pancreas (HP:0002894)2.22055865
79Pancytopenia (HP:0001876)2.20466871
80Abnormality of the fetal cardiovascular system (HP:0010948)2.18524441
81Abnormal umbilical cord blood vessels (HP:0011403)2.18524441
82Single umbilical artery (HP:0001195)2.18524441
83Emotional lability (HP:0000712)2.18034805
84Transposition of the great arteries (HP:0001669)2.17804140
85Abnormal connection of the cardiac segments (HP:0011545)2.17804140
86Abnormal ventriculo-arterial connection (HP:0011563)2.17804140
87Atrophy/Degeneration involving motor neurons (HP:0007373)2.16142429
88Truncus arteriosus (HP:0001660)2.16007125
89Reduced antithrombin III activity (HP:0001976)2.15784259
90Hyperthyroidism (HP:0000836)2.14454203
91Bone marrow hypocellularity (HP:0005528)2.14359183
92Cleft eyelid (HP:0000625)2.12973778
93Poor head control (HP:0002421)2.12722443
94Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.12256912
95Abnormal protein N-linked glycosylation (HP:0012347)2.12256912
96Abnormal protein glycosylation (HP:0012346)2.12256912
97Abnormal glycosylation (HP:0012345)2.12256912
98Hypoplasia of the capital femoral epiphysis (HP:0003090)2.11722673
99Neoplasm of the adrenal cortex (HP:0100641)2.09397901
100Abnormal trabecular bone morphology (HP:0100671)2.09066936
101Microvesicular hepatic steatosis (HP:0001414)2.08761805
102Abnormality of the phalanges of the hallux (HP:0010057)2.07341642
103Elfin facies (HP:0004428)2.06498609
104Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.06374848
105Glossoptosis (HP:0000162)2.03095955
106Hypoplastic left heart (HP:0004383)2.02552157
107Cellular immunodeficiency (HP:0005374)2.00328208
108Unsteady gait (HP:0002317)2.00327531
109Absent radius (HP:0003974)1.99485294
110Abnormal mitochondria in muscle tissue (HP:0008316)1.98667197
111Triphalangeal thumb (HP:0001199)1.98354419
112Missing ribs (HP:0000921)1.98321638
113Fasciculations (HP:0002380)1.96306919
114Agnosia (HP:0010524)1.95370829
115Dysphonia (HP:0001618)1.94758280
116Increased muscle lipid content (HP:0009058)1.94172096
117IgM deficiency (HP:0002850)1.93333593
118CNS demyelination (HP:0007305)1.93252511
119Petechiae (HP:0000967)1.92897818
120Poikiloderma (HP:0001029)1.92138169
121Overriding aorta (HP:0002623)1.92047711
122Lactic acidosis (HP:0003128)1.90657428
123Respiratory failure (HP:0002878)1.90386510
124Type 2 muscle fiber atrophy (HP:0003554)1.90321587
125Renal duplication (HP:0000075)1.90191584
126Tracheoesophageal fistula (HP:0002575)1.89988634
127Respiratory difficulties (HP:0002880)1.89192661
128Abnormality of chromosome stability (HP:0003220)1.88692375
129Hypergonadotropic hypogonadism (HP:0000815)1.88120489
130Unilateral renal agenesis (HP:0000122)1.87364423
131Centrally nucleated skeletal muscle fibers (HP:0003687)1.86867841
132Horseshoe kidney (HP:0000085)1.86686029
133Atresia of the external auditory canal (HP:0000413)1.85896448
134Sparse eyelashes (HP:0000653)1.85174780
135Squamous cell carcinoma (HP:0002860)1.84858877
136Acute necrotizing encephalopathy (HP:0006965)1.84536283
137Abnormality of glycolysis (HP:0004366)1.83563382
138Aplasia involving forearm bones (HP:0009822)1.82242605
139Absent forearm bone (HP:0003953)1.82242605
140Exercise intolerance (HP:0003546)1.81894939
141Tongue fasciculations (HP:0001308)1.81559891
142Poor suck (HP:0002033)1.80954670
143Abnormality of the parathyroid morphology (HP:0011766)1.80920463
144Duplication of thumb phalanx (HP:0009942)1.76069547
145Adducted thumb (HP:0001181)1.75903194
146Down-sloping shoulders (HP:0200021)1.74831166
147Abnormality of the distal phalanges of the toes (HP:0010182)1.74743282
148Patellar dislocation (HP:0002999)1.74425585
149Absent epiphyses (HP:0010577)1.73749414
150Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.73749414
151Redundant skin (HP:0001582)1.72555714
152Short thumb (HP:0009778)1.68841280
153Small epiphyses (HP:0010585)1.66176888
154Hypoplasia of the radius (HP:0002984)1.65875217
155Hyperparathyroidism (HP:0000843)1.64911128
156Increased serum pyruvate (HP:0003542)1.63055908
157Deformed tarsal bones (HP:0008119)1.62955801

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.55191530
2VRK23.91460496
3WEE13.80127263
4NME23.50422538
5SMG13.40167128
6EIF2AK13.04907709
7CDC72.93381006
8STK162.79610636
9TESK22.69751909
10IRAK32.63334052
11ACVR1B2.49327533
12TLK12.45263172
13PIM22.38903744
14NEK22.28696331
15SCYL22.21495590
16TRIB32.14100741
17MAP3K112.06603469
18CDK122.04892178
19VRK12.02594702
20DYRK32.02521605
21SRPK11.97140909
22BRSK21.78884290
23RPS6KB21.73139433
24CDK71.69526523
25PLK11.68135614
26MAPKAPK31.66127422
27TTK1.60526192
28EIF2AK31.56135912
29ICK1.45968070
30KDR1.45816779
31RPS6KA41.43998120
32AURKA1.43884776
33NEK11.42385682
34TSSK61.39845540
35PLK41.35746190
36CDK191.34817818
37TESK11.30258821
38AURKB1.30128806
39MAP3K101.27889802
40TAF11.26559375
41EEF2K1.22257277
42CCNB11.21394435
43PAK41.19542493
44TAOK21.15956057
45BRSK11.11317022
46PRPF4B1.10008884
47PBK1.09933164
48CHEK21.08892507
49CDK41.08259525
50MAP3K81.05918399
51GRK61.05480428
52ATR1.03994485
53NME11.03621301
54MAP4K11.01653928
55IRAK20.96068231
56PIM10.94848705
57ERN10.92755445
58STK100.92476007
59EPHA20.91268565
60FLT30.89672403
61LATS20.88707457
62DMPK0.87674677
63PASK0.87607331
64BRAF0.87526947
65DAPK10.86711553
66PRKD30.85457869
67PAK10.82913036
68BCKDK0.81723954
69CDK80.79096783
70SIK10.78557981
71CHEK10.77870270
72MAP2K30.76709315
73LRRK20.74872558
74MKNK10.71539597
75MAPK110.70873914
76MAPKAPK50.70456746
77RAF10.70224918
78MKNK20.67394165
79TAOK10.65170853
80MUSK0.65051674
81STK40.63215806
82DYRK20.62387357
83PRKCI0.62247847
84ZAP700.62177078
85RPS6KC10.61632980
86RPS6KL10.61632980
87ZAK0.61550740
88CDK90.61529567
89CDK20.60939525
90CSNK1G30.59924268
91ABL20.59635062
92CSNK2A10.57858480
93CSNK2A20.57044419
94MTOR0.51912682
95DAPK30.50146419
96LIMK10.50134035
97PLK30.49608862
98RPS6KA60.48017047
99CDK150.46447644
100MATK0.46271454
101PKN20.46018043
102EPHB20.44729451
103MAP3K30.44348536
104AKT20.43271617
105BLK0.42238657
106MAP2K20.41405728
107BTK0.41397910
108CAMK2G0.41363659
109ILK0.41132076
110CDK140.40638314
111ATM0.39584946
112TGFBR10.38751180
113MST1R0.38682510
114CSNK1G10.38267411
115CDK180.38206475
116ARAF0.37918459
117TTN0.37745100
118CSF1R0.36011410
119TYK20.35807325
120RPS6KA50.35435666
121CSNK1A1L0.33683113
122IKBKB0.32979782
123MAP3K50.32916921
124RPS6KA10.31989368
125EIF2AK20.31869727
126PRKG20.30557352
127CDK10.28353803
128TEC0.26931015
129TBK10.25139881
130CDK11A0.24581038
131DYRK1B0.24168006

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.91153937
2Ribosome_Homo sapiens_hsa030104.66095133
3Mismatch repair_Homo sapiens_hsa034304.07776204
4RNA polymerase_Homo sapiens_hsa030203.54258777
5Proteasome_Homo sapiens_hsa030503.49275407
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.45911956
7Spliceosome_Homo sapiens_hsa030403.13283542
8Base excision repair_Homo sapiens_hsa034102.90768336
9Homologous recombination_Homo sapiens_hsa034402.82844331
10Pyrimidine metabolism_Homo sapiens_hsa002402.81998305
11RNA transport_Homo sapiens_hsa030132.72797032
12Nucleotide excision repair_Homo sapiens_hsa034202.69326239
13One carbon pool by folate_Homo sapiens_hsa006702.37886642
14Cell cycle_Homo sapiens_hsa041102.29529164
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.20971109
16Fanconi anemia pathway_Homo sapiens_hsa034601.89885043
17Sulfur relay system_Homo sapiens_hsa041221.67244526
18RNA degradation_Homo sapiens_hsa030181.64756823
19p53 signaling pathway_Homo sapiens_hsa041151.60797420
20Basal transcription factors_Homo sapiens_hsa030221.56837056
21Folate biosynthesis_Homo sapiens_hsa007901.55589567
22Parkinsons disease_Homo sapiens_hsa050121.42325327
23Purine metabolism_Homo sapiens_hsa002301.35041552
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.31172830
25Oxidative phosphorylation_Homo sapiens_hsa001901.29501962
26Huntingtons disease_Homo sapiens_hsa050161.26981202
27mRNA surveillance pathway_Homo sapiens_hsa030151.25839273
28Pentose phosphate pathway_Homo sapiens_hsa000301.24020660
29Non-homologous end-joining_Homo sapiens_hsa034501.22821912
30Protein export_Homo sapiens_hsa030601.20829671
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.09854744
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08927437
33Epstein-Barr virus infection_Homo sapiens_hsa051691.07327655
34Fatty acid elongation_Homo sapiens_hsa000621.05791522
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.05398906
36Systemic lupus erythematosus_Homo sapiens_hsa053221.00481197
37Biosynthesis of amino acids_Homo sapiens_hsa012300.98938050
38Drug metabolism - other enzymes_Homo sapiens_hsa009830.93316715
39Cyanoamino acid metabolism_Homo sapiens_hsa004600.89561738
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88263597
41Thyroid cancer_Homo sapiens_hsa052160.83207320
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.81091802
43Herpes simplex infection_Homo sapiens_hsa051680.80473148
44Vitamin B6 metabolism_Homo sapiens_hsa007500.79485137
45Sulfur metabolism_Homo sapiens_hsa009200.79180567
46Fructose and mannose metabolism_Homo sapiens_hsa000510.77805384
47Antigen processing and presentation_Homo sapiens_hsa046120.77021778
48Phenylalanine metabolism_Homo sapiens_hsa003600.75383075
49N-Glycan biosynthesis_Homo sapiens_hsa005100.72902260
50Viral carcinogenesis_Homo sapiens_hsa052030.71086093
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70057290
52Selenocompound metabolism_Homo sapiens_hsa004500.68493064
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.67201280
54Alzheimers disease_Homo sapiens_hsa050100.65989678
55Carbon metabolism_Homo sapiens_hsa012000.65846396
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65473592
57Oocyte meiosis_Homo sapiens_hsa041140.64673188
58Galactose metabolism_Homo sapiens_hsa000520.59431894
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59367625
60Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.59225711
61Bladder cancer_Homo sapiens_hsa052190.58436612
62Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56565971
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55478242
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55060310
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51748739
66HTLV-I infection_Homo sapiens_hsa051660.51689238
67Apoptosis_Homo sapiens_hsa042100.51096017
68Glutathione metabolism_Homo sapiens_hsa004800.50892843
69Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49166551
70Shigellosis_Homo sapiens_hsa051310.48221496
71Legionellosis_Homo sapiens_hsa051340.43932542
72Basal cell carcinoma_Homo sapiens_hsa052170.43624685
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43306046
74Metabolic pathways_Homo sapiens_hsa011000.41578349
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40305243
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38697532
77Primary immunodeficiency_Homo sapiens_hsa053400.36590962
78Alcoholism_Homo sapiens_hsa050340.35904745
79Pancreatic cancer_Homo sapiens_hsa052120.34245799
80Tyrosine metabolism_Homo sapiens_hsa003500.30891535
81Small cell lung cancer_Homo sapiens_hsa052220.30099395
82Non-small cell lung cancer_Homo sapiens_hsa052230.29963445
83Hepatitis B_Homo sapiens_hsa051610.28817390
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27833994
85Peroxisome_Homo sapiens_hsa041460.27589485
86Colorectal cancer_Homo sapiens_hsa052100.27234524
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26827430
88Melanoma_Homo sapiens_hsa052180.26092465
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.25694420
90Acute myeloid leukemia_Homo sapiens_hsa052210.25578924
91Transcriptional misregulation in cancer_Homo sapiens_hsa052020.25570428
92Regulation of autophagy_Homo sapiens_hsa041400.25164312
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.24655797
94Steroid biosynthesis_Homo sapiens_hsa001000.24455985
95Fatty acid metabolism_Homo sapiens_hsa012120.24316598
96Cardiac muscle contraction_Homo sapiens_hsa042600.24119426
97Other glycan degradation_Homo sapiens_hsa005110.23882603
98Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.23518874
99Measles_Homo sapiens_hsa051620.22633728
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.20853262
101Vibrio cholerae infection_Homo sapiens_hsa051100.20639641
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19098572
103Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.15744941
104Arginine and proline metabolism_Homo sapiens_hsa003300.15637239
105Hedgehog signaling pathway_Homo sapiens_hsa043400.15231375
106MicroRNAs in cancer_Homo sapiens_hsa052060.14750035
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13499342
108HIF-1 signaling pathway_Homo sapiens_hsa040660.12579651
109Influenza A_Homo sapiens_hsa051640.12076869
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.11881927
111Chronic myeloid leukemia_Homo sapiens_hsa052200.10154693
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.09992386
113Arachidonic acid metabolism_Homo sapiens_hsa005900.09990998
114Notch signaling pathway_Homo sapiens_hsa043300.09288823
115AMPK signaling pathway_Homo sapiens_hsa041520.09011441
116Pyruvate metabolism_Homo sapiens_hsa006200.07578490
117Synaptic vesicle cycle_Homo sapiens_hsa047210.06707862
118Renin-angiotensin system_Homo sapiens_hsa046140.05380411
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.05116271
120Pathways in cancer_Homo sapiens_hsa052000.03507029
121Hippo signaling pathway_Homo sapiens_hsa043900.03236308
122Asthma_Homo sapiens_hsa053100.02106136

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