SAP25

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)4.96379124
2modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.83798459
3positive regulation by organism of defense response of other organism involved in symbiotic interact4.83798459
4modulation by symbiont of host immune response (GO:0052553)4.83798459
5positive regulation by symbiont of host defense response (GO:0052509)4.83798459
6modulation by symbiont of host defense response (GO:0052031)4.83798459
7detection of bacterium (GO:0016045)4.75108104
8detection of other organism (GO:0098543)4.70823242
9macrophage activation involved in immune response (GO:0002281)4.16490924
10negative regulation of erythrocyte differentiation (GO:0045647)4.12524407
11ribosomal small subunit assembly (GO:0000028)4.12131156
12positive regulation of B cell differentiation (GO:0045579)4.07209167
13negative regulation of lymphocyte mediated immunity (GO:0002707)4.07059618
14cellular extravasation (GO:0045123)4.02956984
15regulation of T cell tolerance induction (GO:0002664)4.02717793
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.97910411
17response to interleukin-15 (GO:0070672)3.91992415
18DNA deamination (GO:0045006)3.87190726
19positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.81081034
20detection of external biotic stimulus (GO:0098581)3.80885897
21regulation of mast cell degranulation (GO:0043304)3.79770468
22immunoglobulin mediated immune response (GO:0016064)3.79021909
23negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.74698102
24mast cell activation (GO:0045576)3.71839298
25negative regulation of cell killing (GO:0031342)3.70732822
26negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.70732822
27regulation of tolerance induction (GO:0002643)3.69865727
28leukocyte migration involved in inflammatory response (GO:0002523)3.68222703
29regulation of B cell differentiation (GO:0045577)3.67538372
30negative regulation of leukocyte mediated immunity (GO:0002704)3.66624007
31tolerance induction (GO:0002507)3.65557510
32neutrophil activation involved in immune response (GO:0002283)3.53395102
33negative regulation of T cell mediated immunity (GO:0002710)3.51891393
34regulation of mast cell activation involved in immune response (GO:0033006)3.51629083
35regulation of B cell receptor signaling pathway (GO:0050855)3.49529895
36regulation of myeloid leukocyte mediated immunity (GO:0002886)3.48234910
37regulation of gamma-delta T cell activation (GO:0046643)3.44687799
38regulation of gamma-delta T cell differentiation (GO:0045586)3.41982458
39T cell migration (GO:0072678)3.41654791
40respiratory burst (GO:0045730)3.40970950
41response to peptidoglycan (GO:0032494)3.38894682
42cellular response to interleukin-15 (GO:0071350)3.37094300
43antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.36362573
44antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.36362573
45antigen processing and presentation of endogenous antigen (GO:0019883)3.36316304
46leukocyte aggregation (GO:0070486)3.34998257
47regulation of leukocyte degranulation (GO:0043300)3.34031907
48B cell receptor signaling pathway (GO:0050853)3.33877832
49detection of biotic stimulus (GO:0009595)3.31420428
50positive regulation of mast cell activation (GO:0033005)3.28195442
51regulation of dendritic cell antigen processing and presentation (GO:0002604)3.23738564
52positive thymic T cell selection (GO:0045059)3.22409502
53NIK/NF-kappaB signaling (GO:0038061)3.21758188
54negative regulation of T-helper cell differentiation (GO:0045623)3.20932312
55negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.20932312
56response to host immune response (GO:0052572)3.17247790
57response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.17247790
58cellular response to exogenous dsRNA (GO:0071360)3.16721698
59regulation of mast cell activation (GO:0033003)3.14799279
60histone H3-K4 trimethylation (GO:0080182)3.14721113
61antigen processing and presentation via MHC class Ib (GO:0002475)3.14070287
62negative regulation of innate immune response (GO:0045824)3.13486910
63activated T cell proliferation (GO:0050798)3.13170781
64detection of molecule of bacterial origin (GO:0032490)3.12111694
65mast cell activation involved in immune response (GO:0002279)3.07071815
66mast cell degranulation (GO:0043303)3.07071815
67negative regulation of interleukin-6 production (GO:0032715)3.06360105
68negative regulation of alpha-beta T cell activation (GO:0046636)3.04946736
69negative T cell selection (GO:0043383)3.04568150
70positive regulation of mast cell activation involved in immune response (GO:0033008)3.02431098
71positive regulation of mast cell degranulation (GO:0043306)3.02431098
72negative thymic T cell selection (GO:0045060)3.01806884
73negative regulation of cytokine production involved in immune response (GO:0002719)3.01405822
74regulation of T-helper 2 cell differentiation (GO:0045628)3.00630992
75B cell mediated immunity (GO:0019724)2.98259080
76regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.97396397
77regulation of natural killer cell mediated immunity (GO:0002715)2.97396397
78macrophage activation (GO:0042116)2.96883139
79microglial cell activation (GO:0001774)2.96504972
80response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.95281315
81response to host (GO:0075136)2.95281315
82response to host defenses (GO:0052200)2.95281315
83regulation of T cell mediated cytotoxicity (GO:0001914)2.94935875
84neutrophil activation (GO:0042119)2.94729325
85regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.93492337
86defense response to protozoan (GO:0042832)2.93241085
87mature B cell differentiation (GO:0002335)2.92789150
88regulation of nuclear cell cycle DNA replication (GO:0033262)2.92697503
89leukocyte degranulation (GO:0043299)2.90560366
90negative regulation of granulocyte differentiation (GO:0030853)2.89791259
91mature B cell differentiation involved in immune response (GO:0002313)2.89034095
92response to type I interferon (GO:0034340)2.85881170
93type I interferon signaling pathway (GO:0060337)2.83317389
94cellular response to type I interferon (GO:0071357)2.83317389
95negative regulation of interleukin-12 production (GO:0032695)2.80764347
96telomere maintenance via semi-conservative replication (GO:0032201)2.80675548
97viral transcription (GO:0019083)2.80368827
98myeloid cell activation involved in immune response (GO:0002275)2.79056242
99response to protozoan (GO:0001562)2.76743257
100positive regulation of isotype switching (GO:0045830)2.76250640
101positive regulation of antigen processing and presentation (GO:0002579)2.74938945
102regulation of alpha-beta T cell proliferation (GO:0046640)2.73000865
103telomere maintenance via recombination (GO:0000722)2.72419302
104regulation of interferon-beta biosynthetic process (GO:0045357)2.70635861
105platelet dense granule organization (GO:0060155)2.69711920
106cellular response to zinc ion (GO:0071294)2.69619362
107interferon-gamma production (GO:0032609)2.68764874
108myeloid dendritic cell activation (GO:0001773)2.68428126
109regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.68353716
110response to interferon-beta (GO:0035456)2.65166808
111ribosomal small subunit biogenesis (GO:0042274)2.64830774
112negative regulation of phagocytosis (GO:0050765)2.63838542
113translational termination (GO:0006415)2.63771898
114positive regulation of alpha-beta T cell proliferation (GO:0046641)2.63629958
115regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.63047249
116granulocyte activation (GO:0036230)2.62082549
117positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.60397406
118regulation of necroptotic process (GO:0060544)2.58165507
119regulation of T cell receptor signaling pathway (GO:0050856)2.57491072
120positive regulation of B cell activation (GO:0050871)2.57008995
121interferon-gamma-mediated signaling pathway (GO:0060333)2.56903302
122neutrophil mediated immunity (GO:0002446)2.56610313
123response to muramyl dipeptide (GO:0032495)2.56304916
124cellular response to interferon-beta (GO:0035458)2.55937873
125positive regulation of granulocyte differentiation (GO:0030854)2.55080993
126positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.54997342
127positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.54403115
128regulation of granulocyte differentiation (GO:0030852)2.53117020
129germinal center formation (GO:0002467)2.53005758
130positive regulation of DNA recombination (GO:0045911)2.52312885
131positive T cell selection (GO:0043368)2.50346501
132regulation of RIG-I signaling pathway (GO:0039535)2.50136806
133DNA strand elongation involved in DNA replication (GO:0006271)2.49603551
134kinetochore assembly (GO:0051382)2.48375256
135DNA strand elongation (GO:0022616)2.48032089
136positive regulation of interleukin-2 production (GO:0032743)2.46545919
137T cell homeostasis (GO:0043029)2.46198053
138natural killer cell activation (GO:0030101)2.45786064
139antigen receptor-mediated signaling pathway (GO:0050851)2.45084858
140kinetochore organization (GO:0051383)2.44725025
141lymph node development (GO:0048535)2.43689922
142maturation of SSU-rRNA (GO:0030490)2.43394118
143SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.41196184
144T cell selection (GO:0045058)2.39209430
145positive regulation of defense response to virus by host (GO:0002230)2.38957842
146thymic T cell selection (GO:0045061)2.38926992
147regulation of interleukin-2 biosynthetic process (GO:0045076)2.38474276
148regulation of antigen processing and presentation (GO:0002577)2.38133970
149mitotic recombination (GO:0006312)2.37593200
150modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.36867664

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.11927829
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.11920640
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.95187498
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.44362369
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.40887581
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.16739107
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.13205056
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.07145883
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.97343377
10SCL_19346495_ChIP-Seq_HPC-7_Human2.84810130
11SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.82150370
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79059991
13KDM2B_26808549_Chip-Seq_SUP-B15_Human2.51492809
14VDR_21846776_ChIP-Seq_THP-1_Human2.47994250
15SPI1_23547873_ChIP-Seq_NB4_Human2.47664979
16RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.39034083
17FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.37293129
18MYC_22102868_ChIP-Seq_BL_Human2.36593277
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.30030662
20KDM2B_26808549_Chip-Seq_DND41_Human2.29031048
21IRF8_27001747_Chip-Seq_BMDM_Mouse2.26135253
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.24799935
23STAT4_19710469_ChIP-ChIP_TH1__Mouse2.20930412
24MYB_21317192_ChIP-Seq_ERMYB_Mouse2.11282677
25IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.09559883
26* LXR_22292898_ChIP-Seq_THP-1_Human2.09080491
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.05441896
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.00761654
29FOXM1_23109430_ChIP-Seq_U2OS_Human1.98293745
30MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.97623557
31SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.97525030
32MYB_26560356_Chip-Seq_TH2_Human1.94337944
33* ELK3_25401928_ChIP-Seq_HUVEC_Human1.93829936
34FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.92316842
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.92011111
36MYB_26560356_Chip-Seq_TH1_Human1.88496167
37NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88057640
38NOTCH1_21737748_ChIP-Seq_TLL_Human1.87246484
39SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.86412637
40FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.86411877
41EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.83881689
42RUNX_20019798_ChIP-Seq_JUKART_Human1.83201555
43VDR_24763502_ChIP-Seq_THP-1_Human1.82837123
44MAF_26560356_Chip-Seq_TH1_Human1.82615548
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.81380017
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78856721
47STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.76708115
48NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.76625774
49EGR1_19374776_ChIP-ChIP_THP-1_Human1.76322132
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67895869
51* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.67738276
52ERG_20887958_ChIP-Seq_HPC-7_Mouse1.66146939
53* UTX_26944678_Chip-Seq_JUKART_Human1.65901727
54EST1_17652178_ChIP-ChIP_JURKAT_Human1.63786942
55STAT6_21828071_ChIP-Seq_BEAS2B_Human1.63585377
56MYC_18555785_ChIP-Seq_MESCs_Mouse1.61464522
57JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.59904584
58HOXB4_20404135_ChIP-ChIP_EML_Mouse1.58767016
59BCL6_27268052_Chip-Seq_Bcells_Human1.57439966
60BRD4_27068464_Chip-Seq_AML-cells_Mouse1.56144383
61VDR_23849224_ChIP-Seq_CD4+_Human1.54718239
62GABP_17652178_ChIP-ChIP_JURKAT_Human1.54577234
63* KDM2B_26808549_Chip-Seq_JURKAT_Human1.54194986
64LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.52243373
65BCOR_27268052_Chip-Seq_Bcells_Human1.49284882
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.47962544
67NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.45690254
68IKZF1_21737484_ChIP-ChIP_HCT116_Human1.45190102
69P68_20966046_ChIP-Seq_HELA_Human1.44904659
70KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.43716356
71E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.41902931
72* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.40563037
73GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39784228
74SA1_27219007_Chip-Seq_ERYTHROID_Human1.39596701
75MYC_18358816_ChIP-ChIP_MESCs_Mouse1.39109075
76SPI1_23127762_ChIP-Seq_K562_Human1.38448973
77FOXP3_21729870_ChIP-Seq_TREG_Human1.38328088
78NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.37515743
79ELF1_20517297_ChIP-Seq_JURKAT_Human1.36439051
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.35396643
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.35263128
82MAF_26560356_Chip-Seq_TH2_Human1.33361251
83SRF_21415370_ChIP-Seq_HL-1_Mouse1.32794090
84TCF7_22412390_ChIP-Seq_EML_Mouse1.32570269
85CIITA_25753668_ChIP-Seq_RAJI_Human1.32367519
86HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.29376973
87ETS1_20019798_ChIP-Seq_JURKAT_Human1.28610035
88FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28397082
89NCOR1_26117541_ChIP-Seq_K562_Human1.24998557
90PU.1_20513432_ChIP-Seq_Bcells_Mouse1.23912798
91MYC_19079543_ChIP-ChIP_MESCs_Mouse1.23370505
92RACK7_27058665_Chip-Seq_MCF-7_Human1.23297010
93MYC_19030024_ChIP-ChIP_MESCs_Mouse1.21090396
94CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19831686
95PU_27001747_Chip-Seq_BMDM_Mouse1.18228286
96VDR_24787735_ChIP-Seq_THP-1_Human1.17908962
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15662182
98SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15231166
99GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14660768
100SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.12907041
101KDM2B_26808549_Chip-Seq_K562_Human1.12769648
102GATA1_19941826_ChIP-Seq_K562_Human1.12600158
103CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.10681657
104PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10540012
105NANOG_18555785_ChIP-Seq_MESCs_Mouse1.10452238
106MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.10076770
107CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08830796
108HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.08449378
109SMC4_20622854_ChIP-Seq_HELA_Human1.07656378
110VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.04741979
111GATA3_27048872_Chip-Seq_THYMUS_Human1.04533537
112CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04462934
113PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02907676
114CTCF_21964334_ChIP-Seq_BJAB-B_Human1.02813152
115RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.02559695
116E2F1_20622854_ChIP-Seq_HELA_Human1.02534129
117EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02233200
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02084102
119ELK1_19687146_ChIP-ChIP_HELA_Human1.00784916
120GATA1_19941827_ChIP-Seq_MEL_Mouse1.00772951
121RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00197036
122TET1_21451524_ChIP-Seq_MESCs_Mouse0.99586239
123EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.99391441
124E2F1_21310950_ChIP-Seq_MCF-7_Human0.98800670
125PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98127014
126CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.98096534
127PHF8_20622854_ChIP-Seq_HELA_Human0.97845553
128MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.96633974
129XRN2_22483619_ChIP-Seq_HELA_Human0.94307830
130TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.93103269
131DCP1A_22483619_ChIP-Seq_HELA_Human0.91902173
132* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90156189
133TFEB_21752829_ChIP-Seq_HELA_Human0.89977578
134YY1_21170310_ChIP-Seq_MESCs_Mouse0.89553170
135CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88195154
136FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87191966
137* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.85758378

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.07339512
2MP0005671_abnormal_response_to3.52520995
3MP0000685_abnormal_immune_system3.42148509
4MP0009785_altered_susceptibility_to3.09146934
5MP0001790_abnormal_immune_system2.96772310
6MP0005387_immune_system_phenotype2.96772310
7MP0003763_abnormal_thymus_physiology2.89101883
8MP0001800_abnormal_humoral_immune2.87573356
9MP0002396_abnormal_hematopoietic_system2.85498004
10MP0005000_abnormal_immune_tolerance2.71391777
11MP0005025_abnormal_response_to2.65823700
12MP0003436_decreased_susceptibility_to2.62370452
13MP0002452_abnormal_antigen_presenting2.62307642
14MP0002723_abnormal_immune_serum2.58798437
15MP0008057_abnormal_DNA_replication2.55204234
16MP0002420_abnormal_adaptive_immunity2.54341153
17MP0001819_abnormal_immune_cell2.53791622
18MP0002419_abnormal_innate_immunity2.53337252
19MP0002148_abnormal_hypersensitivity_rea2.51992923
20MP0002398_abnormal_bone_marrow2.43631404
21MP0005174_abnormal_tail_pigmentation2.35715979
22MP0005464_abnormal_platelet_physiology2.28149807
23MP0005075_abnormal_melanosome_morpholog2.22939184
24MP0000716_abnormal_immune_system2.17940515
25MP0002405_respiratory_system_inflammati2.11811126
26MP0009333_abnormal_splenocyte_physiolog2.10507482
27MP0000689_abnormal_spleen_morphology2.05975948
28MP0002722_abnormal_immune_system2.04340154
29MP0003693_abnormal_embryo_hatching2.02623836
30MP0010155_abnormal_intestine_physiology1.92720646
31MP0005397_hematopoietic_system_phenotyp1.91840224
32MP0001545_abnormal_hematopoietic_system1.91840224
33MP0002166_altered_tumor_susceptibility1.90114539
34MP0008260_abnormal_autophagy1.86031956
35MP0003724_increased_susceptibility_to1.85582983
36MP0002429_abnormal_blood_cell1.85479479
37MP0006082_CNS_inflammation1.82071189
38MP0003866_abnormal_defecation1.77820973
39MP0004808_abnormal_hematopoietic_stem1.75961433
40MP0000703_abnormal_thymus_morphology1.75172087
41MP0001853_heart_inflammation1.72680149
42MP0000465_gastrointestinal_hemorrhage1.72147936
43MP0009278_abnormal_bone_marrow1.72125803
44MP0001873_stomach_inflammation1.71156332
45MP0010094_abnormal_chromosome_stability1.70107539
46MP0000490_abnormal_crypts_of1.67339804
47MP0008058_abnormal_DNA_repair1.62156484
48MP0002006_tumorigenesis1.57717547
49MP0003077_abnormal_cell_cycle1.56170404
50MP0001845_abnormal_inflammatory_respons1.53011650
51MP0002132_abnormal_respiratory_system1.48958155
52MP0003303_peritoneal_inflammation1.44536638
53MP0003183_abnormal_peptide_metabolism1.43226409
54MP0003172_abnormal_lysosome_physiology1.40057355
55MP0005451_abnormal_body_composition1.38098992
56MP0000858_altered_metastatic_potential1.37490498
57MP0003111_abnormal_nucleus_morphology1.36758999
58MP0000015_abnormal_ear_pigmentation1.34498659
59MP0003828_pulmonary_edema1.30010088
60MP0005058_abnormal_lysosome_morphology1.25351836
61MP0008469_abnormal_protein_level1.22693789
62MP0005310_abnormal_salivary_gland1.22104929
63MP0002019_abnormal_tumor_incidence1.20612075
64MP0003191_abnormal_cellular_cholesterol1.15162028
65MP0002095_abnormal_skin_pigmentation1.14748629
66MP0001986_abnormal_taste_sensitivity1.14543264
67MP0004947_skin_inflammation1.14047605
68MP0000371_diluted_coat_color1.07109883
69MP0006292_abnormal_olfactory_placode1.06521397
70MP0002277_abnormal_respiratory_mucosa1.04307494
71MP0008007_abnormal_cellular_replicative1.02805368
72MP0002138_abnormal_hepatobiliary_system1.01344750
73MP0002933_joint_inflammation0.99883071
74MP0004883_abnormal_blood_vessel0.99876056
75MP0001533_abnormal_skeleton_physiology0.95772456
76MP0003806_abnormal_nucleotide_metabolis0.90767710
77MP0009840_abnormal_foam_cell0.90338948
78MP0005390_skeleton_phenotype0.89810159
79MP0003075_altered_response_to0.89783405
80MP0004957_abnormal_blastocyst_morpholog0.88672253
81MP0000313_abnormal_cell_death0.85704965
82MP0008877_abnormal_DNA_methylation0.81585150
83MP0005166_decreased_susceptibility_to0.81018103
84MP0003786_premature_aging0.80642924
85MP0002254_reproductive_system_inflammat0.79748878
86MP0002075_abnormal_coat/hair_pigmentati0.76816248
87MP0003690_abnormal_glial_cell0.75206847
88MP0003448_altered_tumor_morphology0.73605479
89MP0002998_abnormal_bone_remodeling0.72333147
90MP0005377_hearing/vestibular/ear_phenot0.72222621
91MP0003878_abnormal_ear_physiology0.72222621
92MP0005076_abnormal_cell_differentiation0.72181544
93MP0005164_abnormal_response_to0.71365848
94MP0009764_decreased_sensitivity_to0.70649609
95MP0008961_abnormal_basal_metabolism0.70561114
96MP0009763_increased_sensitivity_to0.70133206
97MP0000569_abnormal_digit_pigmentation0.68886972
98MP0001186_pigmentation_phenotype0.66242644
99MP0008004_abnormal_stomach_pH0.66088369
100MP0003795_abnormal_bone_structure0.65883894
101MP0004381_abnormal_hair_follicle0.63966942
102MP0003300_gastrointestinal_ulcer0.63937207
103MP0005083_abnormal_biliary_tract0.63314388
104MP0000343_altered_response_to0.62880523
105MP0008874_decreased_physiological_sensi0.61712744
106MP0004510_myositis0.61227141
107MP0004133_heterotaxia0.61157587
108MP0003186_abnormal_redox_activity0.61127957
109MP0008995_early_reproductive_senescence0.61064682
110MP0009765_abnormal_xenobiotic_induced0.60088618
111MP0000249_abnormal_blood_vessel0.60066398
112MP0002009_preneoplasia0.59786833
113MP0005409_darkened_coat_color0.59657816
114MP0010307_abnormal_tumor_latency0.59520154
115MP0005381_digestive/alimentary_phenotyp0.58192541
116MP0004130_abnormal_muscle_cell0.58018067
117MP0000350_abnormal_cell_proliferation0.57206263
118MP0003453_abnormal_keratinocyte_physiol0.55028594
119MP0003787_abnormal_imprinting0.54872150
120MP0001764_abnormal_homeostasis0.53349346
121MP0000604_amyloidosis0.53315104
122MP0003045_fibrosis0.52555934
123MP0002928_abnormal_bile_duct0.52208882
124MP0001663_abnormal_digestive_system0.52062190
125MP0005535_abnormal_body_temperature0.51267532
126MP0005670_abnormal_white_adipose0.50717192
127MP0001348_abnormal_lacrimal_gland0.50622505
128MP0000477_abnormal_intestine_morphology0.50518789
129MP0004185_abnormal_adipocyte_glucose0.49358472
130MP0009115_abnormal_fat_cell0.47801395
131MP0001851_eye_inflammation0.47584678
132MP0002693_abnormal_pancreas_physiology0.44656350
133MP0003656_abnormal_erythrocyte_physiolo0.42755867
134MP0000470_abnormal_stomach_morphology0.42397672

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.24796145
2Recurrent bacterial skin infections (HP:0005406)4.57629793
3Panhypogammaglobulinemia (HP:0003139)4.21487669
4Elevated erythrocyte sedimentation rate (HP:0003565)4.14480431
5Recurrent viral infections (HP:0004429)4.05626144
6Myositis (HP:0100614)4.05068922
7Eczematoid dermatitis (HP:0000976)4.00368776
8Increased IgE level (HP:0003212)4.00254485
9Recurrent fungal infections (HP:0002841)3.95039940
10Abnormal delayed hypersensitivity skin test (HP:0002963)3.93055430
11Gastrointestinal infarctions (HP:0005244)3.90544008
12Spontaneous hematomas (HP:0007420)3.67932176
13IgM deficiency (HP:0002850)3.50740498
14Chronic otitis media (HP:0000389)3.50396964
15Recurrent cutaneous fungal infections (HP:0011370)3.39585942
16Chronic mucocutaneous candidiasis (HP:0002728)3.39585942
17Agammaglobulinemia (HP:0004432)3.37350735
18Meningitis (HP:0001287)3.37179701
19Recurrent skin infections (HP:0001581)3.34249493
20Thrombocytosis (HP:0001894)3.27188133
21Retrobulbar optic neuritis (HP:0100654)3.27011872
22Optic neuritis (HP:0100653)3.27011872
23Hypochromic anemia (HP:0001931)3.26027937
24Abnormality of T cell physiology (HP:0011840)3.23880876
25Hypochromic microcytic anemia (HP:0004840)3.20719731
26Chest pain (HP:0100749)3.17429091
27Abnormality of T cells (HP:0002843)3.14506094
28Abnormal number of erythroid precursors (HP:0012131)3.02777861
29Pustule (HP:0200039)3.01874326
30Urticaria (HP:0001025)3.00282590
31Reticulocytopenia (HP:0001896)2.99150453
32Orchitis (HP:0100796)2.96956474
33Abnormality of cells of the erythroid lineage (HP:0012130)2.95116107
34Mediastinal lymphadenopathy (HP:0100721)2.92194067
35T lymphocytopenia (HP:0005403)2.84944557
36Obstructive lung disease (HP:0006536)2.83762797
37Chronic obstructive pulmonary disease (HP:0006510)2.83762797
38Abnormality of macrophages (HP:0004311)2.83153203
39Chromsome breakage (HP:0040012)2.77915461
40Episodic fever (HP:0001954)2.76463516
41Abnormality of T cell number (HP:0011839)2.74465931
42Abnormality of B cell number (HP:0010975)2.74390482
43B lymphocytopenia (HP:0010976)2.74390482
44Petechiae (HP:0000967)2.74276278
45Increased IgM level (HP:0003496)2.71645748
46Encephalitis (HP:0002383)2.69341233
47Recurrent bronchitis (HP:0002837)2.68624755
48Cellulitis (HP:0100658)2.66833507
49Lymphopenia (HP:0001888)2.66779391
50Chromosomal breakage induced by crosslinking agents (HP:0003221)2.66135990
51Prolonged bleeding time (HP:0003010)2.65800060
52Stomatitis (HP:0010280)2.65675047
53IgG deficiency (HP:0004315)2.61785233
54Vasculitis (HP:0002633)2.59697490
55Granulocytopenia (HP:0001913)2.58031161
56Severe combined immunodeficiency (HP:0004430)2.57919097
57Eosinophilia (HP:0001880)2.57062644
58Leukocytosis (HP:0001974)2.55652312
59Colitis (HP:0002583)2.55152790
60Abnormality of cells of the lymphoid lineage (HP:0012140)2.53549357
61Abnormality of eosinophils (HP:0001879)2.52727272
62Inflammation of the large intestine (HP:0002037)2.51842401
63Aplastic anemia (HP:0001915)2.51412343
64Pulmonary embolism (HP:0002204)2.50820323
65Vacuolated lymphocytes (HP:0001922)2.49502597
66Lymphoma (HP:0002665)2.48882663
67Papilledema (HP:0001085)2.45927077
68Abnormality of DNA repair (HP:0003254)2.45835665
69Gastrointestinal inflammation (HP:0004386)2.42935282
70Recurrent pneumonia (HP:0006532)2.41274895
71Albinism (HP:0001022)2.41268989
72Thyroiditis (HP:0100646)2.40488933
73Anorexia (HP:0002039)2.39174221
74Combined immunodeficiency (HP:0005387)2.37418159
75Periodontitis (HP:0000704)2.36608827
76Microcytic anemia (HP:0001935)2.36500273
77Recurrent lower respiratory tract infections (HP:0002783)2.35949087
78Abnormality of the prostate (HP:0008775)2.34812159
79Sepsis (HP:0100806)2.34276934
80Purpura (HP:0000979)2.32913050
81Myelodysplasia (HP:0002863)2.31168705
82Poikiloderma (HP:0001029)2.30156438
83Recurrent gram-negative bacterial infections (HP:0005420)2.29259976
84Autoimmune thrombocytopenia (HP:0001973)2.29127382
85Arterial thrombosis (HP:0004420)2.28767381
86Loss of speech (HP:0002371)2.26987604
87Gingival bleeding (HP:0000225)2.25562675
88Keratoconjunctivitis sicca (HP:0001097)2.24306100
89Gingivitis (HP:0000230)2.23800337
90Abnormality of the pleura (HP:0002103)2.23688799
91Premature loss of primary teeth (HP:0006323)2.18383522
92Absent rod-and cone-mediated responses on ERG (HP:0007688)2.18113330
93Verrucae (HP:0200043)2.18080436
94Papilloma (HP:0012740)2.18080436
95Epistaxis (HP:0000421)2.16037303
96Increased serum ferritin (HP:0003281)2.15596402
97Hepatosplenomegaly (HP:0001433)2.13511488
98Neutropenia (HP:0001875)2.11749508
99Dysostosis multiplex (HP:0000943)2.09398602
100Abnormality of the fingertips (HP:0001211)2.09336875
101Restrictive lung disease (HP:0002091)2.07901331
102Recurrent sinusitis (HP:0011108)2.07161912
103Pulmonary infiltrates (HP:0002113)2.06568412
104Skin ulcer (HP:0200042)2.05916092
105Pallor (HP:0000980)2.05530598
106Increased cerebral lipofuscin (HP:0011813)2.05332246
107Keratoconjunctivitis (HP:0001096)2.03322042
108Hemoptysis (HP:0002105)2.02758694
109Amyloidosis (HP:0011034)2.02253429
110Metaphyseal cupping (HP:0003021)2.01958775
111Renal cortical cysts (HP:0000803)2.01591441
112Hypergammaglobulinemia (HP:0010702)2.01309943
113Acne (HP:0001061)2.01252308
114Cheilitis (HP:0100825)1.98755614
115Systemic lupus erythematosus (HP:0002725)1.98483178
116Peritonitis (HP:0002586)1.96892895
117Type I transferrin isoform profile (HP:0003642)1.96428015
118Slow saccadic eye movements (HP:0000514)1.95948327
119Thoracic kyphosis (HP:0002942)1.95384374
120Clubbing of toes (HP:0100760)1.93232963
121Abnormality of the renal collecting system (HP:0004742)1.93136422
122IgA deficiency (HP:0002720)1.92624044
123Glomerulopathy (HP:0100820)1.92420316
124Abnormality of iron homeostasis (HP:0011031)1.91518079
125Gangrene (HP:0100758)1.90553240
126Leukopenia (HP:0001882)1.90345262
127Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.89885553
128Gastrointestinal stroma tumor (HP:0100723)1.88821785
129Hypertensive crisis (HP:0100735)1.88618804
130Obstructive sleep apnea (HP:0002870)1.87982928
131Nasal polyposis (HP:0100582)1.85848413
132Birth length less than 3rd percentile (HP:0003561)1.85338099
133Exertional dyspnea (HP:0002875)1.85154123
134Duplicated collecting system (HP:0000081)1.85079364
135Bone marrow hypocellularity (HP:0005528)1.84240678
136Viral hepatitis (HP:0006562)1.83793166
137Emphysema (HP:0002097)1.83403187
138Osteomyelitis (HP:0002754)1.83366537
139Acute hepatic failure (HP:0006554)1.83208959
140Malnutrition (HP:0004395)1.82372153
141Increased neuronal autofluorescent lipopigment (HP:0002074)1.82245132
142Keratitis (HP:0000491)1.80214998
14311 pairs of ribs (HP:0000878)1.79711812
144Abnormal platelet function (HP:0011869)1.79153899

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.23446706
2IRAK43.46886252
3TXK3.36143792
4PRPF4B2.64128335
5BLK2.60101480
6KIT2.39232243
7MAP3K142.37524341
8BTK2.28279305
9ZAP702.17333727
10SIK32.17052369
11IKBKE2.15111879
12JAK32.13540591
13TEC2.12476225
14TYK22.03186568
15TAOK31.99688066
16IRAK31.84815216
17TRIB31.84209367
18IKBKB1.80719261
19SIK11.73468822
20EPHB11.73020740
21MAP2K31.69363738
22PIM21.68903687
23RIPK41.68633907
24TBK11.65730780
25STK101.64310584
26CLK11.62186659
27NME21.61757341
28SYK1.60124939
29CSF1R1.48484466
30ITK1.46720614
31FLT31.44591040
32LCK1.40753838
33CSK1.39034485
34STK161.38733911
35MARK21.37525021
36LYN1.36523144
37WEE11.30349419
38GRK61.29307312
39TGFBR21.29266191
40STK41.28802432
41HCK1.27173665
42SRPK11.25333697
43PIM11.24139249
44NLK1.19474291
45YES11.17832285
46FGR1.13866643
47MAP3K11.12624298
48VRK11.10895376
49CDK71.08028263
50SMG11.07887855
51MAP2K61.05609868
52TESK21.05245685
53CHUK1.01436070
54CDK121.01126375
55PTK61.00739435
56BRSK20.99667891
57ZAK0.96092410
58MAP3K70.95153595
59ATR0.94866828
60BRD40.93669917
61CDC42BPA0.93059190
62FES0.92317764
63EIF2AK30.92205499
64TNIK0.92115892
65TLK10.91103174
66PRKD20.90805012
67JAK10.89981954
68TAOK10.88654674
69PDK10.81165238
70CAMKK10.80170827
71TAOK20.77863377
72EIF2AK20.76717000
73MATK0.76280007
74PLK40.75527532
75DYRK30.73607714
76MAPK120.73529015
77MAPK150.71098212
78RPS6KB20.70903590
79MUSK0.70563414
80NEK20.70331836
81ADRBK20.70157774
82CDC70.70021260
83PDPK10.69932597
84DYRK1B0.69284831
85KSR20.69235153
86MAPK70.67801679
87MAP3K80.65931719
88IRAK20.65277400
89CDK190.65246140
90HIPK20.63682479
91RPS6KA60.63598102
92GRK70.63276446
93IRAK10.60921265
94MAP3K110.60491381
95CDK80.60095107
96FYN0.56814153
97JAK20.55983435
98MAP3K130.55627585
99MAPK110.55206804
100MAP3K120.54885768
101SIK20.54821052
102RAF10.54654521
103LRRK20.54589638
104TRPM70.54349287
105BMX0.54031558
106PRKCQ0.53843920
107CDK30.53450917
108PLK10.52835314
109MAP3K100.52510802
110RPS6KC10.51333624
111RPS6KL10.51333624
112STK110.50310441
113BMPR20.50085896
114RPS6KA50.50014042
115RIPK10.49032787
116RPS6KA40.47705565
117MARK30.47631295
118TNK20.46570617
119TTK0.45877497
120PKN20.45454503
121FGFR40.44388648
122CDK40.44223222
123PRKCH0.44157102
124PTK2B0.43454615
125FGFR30.42934368
126PIK3CG0.42276269
127STK380.41809450
128PASK0.41655513
129MAP3K60.41334746
130AURKB0.41098193
131MAP2K20.40332309
132MAPKAPK20.40190308
133MAP3K30.40169212
134ACVR1B0.39695887
135ERN10.37959550
136ABL10.37506434
137ICK0.36069303
138CAMKK20.35463287
139RPS6KA20.34849575
140RET0.34649482
141MAP2K40.32458365
142MAPK40.32424706

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.69643610
2DNA replication_Homo sapiens_hsa030302.87589902
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.62859598
4Ribosome_Homo sapiens_hsa030102.61829250
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.46497740
6Mismatch repair_Homo sapiens_hsa034302.33752138
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.30122921
8Base excision repair_Homo sapiens_hsa034102.25645595
9Leishmaniasis_Homo sapiens_hsa051402.10657134
10Homologous recombination_Homo sapiens_hsa034402.09618523
11Measles_Homo sapiens_hsa051622.05832385
12RNA polymerase_Homo sapiens_hsa030202.05492944
13B cell receptor signaling pathway_Homo sapiens_hsa046621.90600973
14Graft-versus-host disease_Homo sapiens_hsa053321.88983806
15Hematopoietic cell lineage_Homo sapiens_hsa046401.85808212
16Herpes simplex infection_Homo sapiens_hsa051681.84141188
17Antigen processing and presentation_Homo sapiens_hsa046121.83940385
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.81979729
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.77740301
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.77511636
21Other glycan degradation_Homo sapiens_hsa005111.74935632
22Type I diabetes mellitus_Homo sapiens_hsa049401.73670719
23Fanconi anemia pathway_Homo sapiens_hsa034601.70707699
24Non-homologous end-joining_Homo sapiens_hsa034501.65878218
25Osteoclast differentiation_Homo sapiens_hsa043801.60186711
26Spliceosome_Homo sapiens_hsa030401.54073613
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.51626885
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.50241311
29Allograft rejection_Homo sapiens_hsa053301.49117022
30Pyrimidine metabolism_Homo sapiens_hsa002401.41552787
31Nucleotide excision repair_Homo sapiens_hsa034201.36927605
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.36066991
33T cell receptor signaling pathway_Homo sapiens_hsa046601.34782137
34Staphylococcus aureus infection_Homo sapiens_hsa051501.29712629
35Influenza A_Homo sapiens_hsa051641.23447948
36RNA degradation_Homo sapiens_hsa030181.20718377
37VEGF signaling pathway_Homo sapiens_hsa043701.17829892
38Non-small cell lung cancer_Homo sapiens_hsa052231.16672234
39Transcriptional misregulation in cancer_Homo sapiens_hsa052021.16582036
40Jak-STAT signaling pathway_Homo sapiens_hsa046301.16438003
41Pertussis_Homo sapiens_hsa051331.14787171
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.10220365
43p53 signaling pathway_Homo sapiens_hsa041151.10134277
44Acute myeloid leukemia_Homo sapiens_hsa052211.08177749
45Phagosome_Homo sapiens_hsa041451.04287745
46Cell cycle_Homo sapiens_hsa041101.03999264
47Epstein-Barr virus infection_Homo sapiens_hsa051691.01720260
48Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.01691949
49Tuberculosis_Homo sapiens_hsa051521.01431217
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.99712768
51Hepatitis B_Homo sapiens_hsa051610.99664822
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99621581
53Toxoplasmosis_Homo sapiens_hsa051450.99438402
54Shigellosis_Homo sapiens_hsa051310.99237657
55Apoptosis_Homo sapiens_hsa042100.98672023
56Basal transcription factors_Homo sapiens_hsa030220.98482697
57Chemokine signaling pathway_Homo sapiens_hsa040620.96695407
58Malaria_Homo sapiens_hsa051440.94275758
59Autoimmune thyroid disease_Homo sapiens_hsa053200.93728838
60Asthma_Homo sapiens_hsa053100.90427978
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.89176876
62Legionellosis_Homo sapiens_hsa051340.86630773
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86596676
64Neurotrophin signaling pathway_Homo sapiens_hsa047220.84720404
65Notch signaling pathway_Homo sapiens_hsa043300.84351253
66Protein export_Homo sapiens_hsa030600.83026835
67Endocytosis_Homo sapiens_hsa041440.80982486
68Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79440776
69Glycerophospholipid metabolism_Homo sapiens_hsa005640.78579280
70TNF signaling pathway_Homo sapiens_hsa046680.78083941
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.77143821
72Choline metabolism in cancer_Homo sapiens_hsa052310.76694227
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76341474
74Prolactin signaling pathway_Homo sapiens_hsa049170.74738752
75Leukocyte transendothelial migration_Homo sapiens_hsa046700.74389614
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73129292
77Platelet activation_Homo sapiens_hsa046110.73116603
78Renal cell carcinoma_Homo sapiens_hsa052110.73012873
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72027351
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71948979
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.71499307
82RNA transport_Homo sapiens_hsa030130.70260225
83Inositol phosphate metabolism_Homo sapiens_hsa005620.68531076
84Purine metabolism_Homo sapiens_hsa002300.67101518
85Rheumatoid arthritis_Homo sapiens_hsa053230.66896423
86GnRH signaling pathway_Homo sapiens_hsa049120.66148338
87Regulation of autophagy_Homo sapiens_hsa041400.64909348
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64232292
89Arachidonic acid metabolism_Homo sapiens_hsa005900.63403015
90mTOR signaling pathway_Homo sapiens_hsa041500.63010434
91Chronic myeloid leukemia_Homo sapiens_hsa052200.61894126
92Viral myocarditis_Homo sapiens_hsa054160.61576172
93Pancreatic cancer_Homo sapiens_hsa052120.61482093
94HTLV-I infection_Homo sapiens_hsa051660.60922756
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.60378112
96Lysosome_Homo sapiens_hsa041420.60079964
97Hepatitis C_Homo sapiens_hsa051600.59724914
98Viral carcinogenesis_Homo sapiens_hsa052030.59397452
99FoxO signaling pathway_Homo sapiens_hsa040680.59381137
100MAPK signaling pathway_Homo sapiens_hsa040100.58076148
101Proteasome_Homo sapiens_hsa030500.57404757
102Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57011212
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56516769
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56133727
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56026420
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.55135497
107Endometrial cancer_Homo sapiens_hsa052130.55022728
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.54983457
109Insulin resistance_Homo sapiens_hsa049310.54956082
110Systemic lupus erythematosus_Homo sapiens_hsa053220.52051544
111Salmonella infection_Homo sapiens_hsa051320.51554621
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49877579
113Caffeine metabolism_Homo sapiens_hsa002320.48217878
114African trypanosomiasis_Homo sapiens_hsa051430.47857577
115Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47205300
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.47075179
117N-Glycan biosynthesis_Homo sapiens_hsa005100.45889877
118Rap1 signaling pathway_Homo sapiens_hsa040150.45025069
119Amoebiasis_Homo sapiens_hsa051460.43187802
120Dorso-ventral axis formation_Homo sapiens_hsa043200.42911922
121ErbB signaling pathway_Homo sapiens_hsa040120.42465217
122One carbon pool by folate_Homo sapiens_hsa006700.41914245
123ABC transporters_Homo sapiens_hsa020100.40190596
124Folate biosynthesis_Homo sapiens_hsa007900.39752074
125HIF-1 signaling pathway_Homo sapiens_hsa040660.38859678
126mRNA surveillance pathway_Homo sapiens_hsa030150.38723186
127Insulin signaling pathway_Homo sapiens_hsa049100.35811635
128Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35283429
129AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.34755756
130Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33724865
131Type II diabetes mellitus_Homo sapiens_hsa049300.32653808
132Ras signaling pathway_Homo sapiens_hsa040140.32549398
133Small cell lung cancer_Homo sapiens_hsa052220.28544383
134Colorectal cancer_Homo sapiens_hsa052100.28063839
135Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27708837
136Pentose phosphate pathway_Homo sapiens_hsa000300.27013934
137Sphingolipid metabolism_Homo sapiens_hsa006000.26275105
138Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.26010833

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