SAPCD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.75513110
2regulation of attachment of spindle microtubules to kinetochore (GO:0051988)5.67090653
3mitotic sister chromatid segregation (GO:0000070)5.20691723
4regulation of spindle organization (GO:0090224)5.08885561
5protein localization to kinetochore (GO:0034501)5.06545546
6metaphase plate congression (GO:0051310)4.79517239
7purine nucleobase biosynthetic process (GO:0009113)4.76466257
8protein localization to chromosome, centromeric region (GO:0071459)4.64320589
9sister chromatid segregation (GO:0000819)4.61008428
10nucleobase biosynthetic process (GO:0046112)4.55995870
11proline biosynthetic process (GO:0006561)4.49390214
12regulation of translational fidelity (GO:0006450)4.41583476
13kinetochore organization (GO:0051383)4.32011591
14kinetochore assembly (GO:0051382)4.30454521
15establishment of chromosome localization (GO:0051303)4.22992383
16spindle checkpoint (GO:0031577)4.22950070
17DNA deamination (GO:0045006)4.19476814
18positive regulation of chromosome segregation (GO:0051984)4.19316294
19DNA replication checkpoint (GO:0000076)4.14235358
20regulation of mitotic spindle organization (GO:0060236)4.12508011
21maturation of SSU-rRNA (GO:0030490)4.12412356
22regulation of chromosome segregation (GO:0051983)4.11001491
23negative regulation of chromosome segregation (GO:0051985)4.10875177
24ribosome assembly (GO:0042255)4.10422242
25CENP-A containing nucleosome assembly (GO:0034080)4.10035382
26negative regulation of mitotic metaphase/anaphase transition (GO:0045841)4.05804469
27negative regulation of sister chromatid segregation (GO:0033046)4.05804469
28negative regulation of mitotic sister chromatid separation (GO:2000816)4.05804469
29negative regulation of mitotic sister chromatid segregation (GO:0033048)4.05804469
30spindle assembly checkpoint (GO:0071173)4.04651709
31mitotic spindle assembly checkpoint (GO:0007094)4.04000348
32DNA strand elongation involved in DNA replication (GO:0006271)4.02065279
33mitotic spindle checkpoint (GO:0071174)3.99857539
34DNA topological change (GO:0006265)3.99234283
35regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.96687322
36mitotic nuclear envelope disassembly (GO:0007077)3.94694581
37nuclear pore complex assembly (GO:0051292)3.94397874
38negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.93219372
39DNA replication initiation (GO:0006270)3.92473039
40chromatin remodeling at centromere (GO:0031055)3.92347352
41attachment of spindle microtubules to kinetochore (GO:0008608)3.88936794
42protein complex localization (GO:0031503)3.88768319
43mitotic chromosome condensation (GO:0007076)3.83362973
44ribosome biogenesis (GO:0042254)3.82956026
45DNA strand elongation (GO:0022616)3.81292822
46anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.79932061
47regulation of mitotic metaphase/anaphase transition (GO:0030071)3.76476744
48chromosome condensation (GO:0030261)3.76166921
49DNA replication-independent nucleosome assembly (GO:0006336)3.74659182
50DNA replication-independent nucleosome organization (GO:0034724)3.74659182
51regulation of mammary gland epithelial cell proliferation (GO:0033599)3.72353558
52telomere maintenance via semi-conservative replication (GO:0032201)3.71308576
53protein localization to chromosome (GO:0034502)3.68338648
54proteasome assembly (GO:0043248)3.67791091
55regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.67418436
56spliceosomal snRNP assembly (GO:0000387)3.66799388
57formation of translation preinitiation complex (GO:0001731)3.64748520
58nuclear envelope disassembly (GO:0051081)3.63540798
59membrane disassembly (GO:0030397)3.63540798
60regulation of mitotic sister chromatid separation (GO:0010965)3.61825402
61regulation of mitotic sister chromatid segregation (GO:0033047)3.61825402
62regulation of sister chromatid segregation (GO:0033045)3.61825402
63heterochromatin organization (GO:0070828)3.59863860
64regulation of exit from mitosis (GO:0007096)3.59859398
65DNA unwinding involved in DNA replication (GO:0006268)3.57272376
66ribosomal large subunit biogenesis (GO:0042273)3.55875343
67ribonucleoprotein complex biogenesis (GO:0022613)3.55333321
68regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.54911876
69histone exchange (GO:0043486)3.52256871
70positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.49643764
71microtubule depolymerization (GO:0007019)3.49147078
72cellular protein complex localization (GO:0034629)3.46346721
73folic acid metabolic process (GO:0046655)3.43518924
74nuclear pore organization (GO:0006999)3.39310456
75chromosome segregation (GO:0007059)3.39277278
76negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.37627190
77positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.37205190
78positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.37205190
79positive regulation of mitotic sister chromatid separation (GO:1901970)3.37205190
80negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.37183767
81rRNA processing (GO:0006364)3.36531522
82regulation of translational termination (GO:0006449)3.35857565
83rRNA modification (GO:0000154)3.33710439
84mitotic recombination (GO:0006312)3.32673177
85telomere maintenance via recombination (GO:0000722)3.32497774
86DNA replication-dependent nucleosome assembly (GO:0006335)3.31937138
87DNA replication-dependent nucleosome organization (GO:0034723)3.31937138
88spliceosomal complex assembly (GO:0000245)3.30093496
89negative regulation of mitosis (GO:0045839)3.29952232
90regulation of centrosome cycle (GO:0046605)3.28482847
91rRNA metabolic process (GO:0016072)3.27527660
92transcription elongation from RNA polymerase III promoter (GO:0006385)3.24302959
93termination of RNA polymerase III transcription (GO:0006386)3.24302959
94translational initiation (GO:0006413)3.23234728
95peptidyl-arginine omega-N-methylation (GO:0035247)3.21582932
96viral transcription (GO:0019083)3.18100257
97DNA packaging (GO:0006323)3.17974407
98regulation of telomere maintenance via telomerase (GO:0032210)3.17712966
99regulation of double-strand break repair via homologous recombination (GO:0010569)3.16280255
100histone-serine phosphorylation (GO:0035404)3.16196256
101ribosomal small subunit assembly (GO:0000028)3.16074454
102nucleobase-containing small molecule interconversion (GO:0015949)3.16048463
103activation of Rac GTPase activity (GO:0032863)3.14681008
104positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.13919929
105translational termination (GO:0006415)3.13709724
106nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.12699693
107protein K6-linked ubiquitination (GO:0085020)3.11357100
108spliceosomal tri-snRNP complex assembly (GO:0000244)3.10970080
109nuclear envelope organization (GO:0006998)3.08712197
110telomere maintenance via telomere lengthening (GO:0010833)3.08543202
111viral mRNA export from host cell nucleus (GO:0046784)3.08394894
112ribosomal small subunit biogenesis (GO:0042274)3.08036420
113translational elongation (GO:0006414)3.07466678
114rRNA transcription (GO:0009303)3.06060423
115negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.05119710
116negative regulation of ligase activity (GO:0051352)3.05119710
117proline metabolic process (GO:0006560)3.04003613
118DNA duplex unwinding (GO:0032508)3.03911564
119establishment of integrated proviral latency (GO:0075713)3.03862782
120negative regulation of DNA-templated transcription, elongation (GO:0032785)3.01754459
121negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.01754459
122regulation of nuclear cell cycle DNA replication (GO:0033262)2.99762050
123transcription elongation from RNA polymerase I promoter (GO:0006362)2.99635896
124negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.98282706
125DNA conformation change (GO:0071103)2.97819236
126mitotic sister chromatid cohesion (GO:0007064)2.97137814
127regulation of sister chromatid cohesion (GO:0007063)2.95433056
128pore complex assembly (GO:0046931)2.94122561
129negative regulation of mRNA processing (GO:0050686)2.89105302
130desmosome organization (GO:0002934)2.88864594
131regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.88249690
132DNA geometric change (GO:0032392)2.87952873
133negative regulation of mRNA metabolic process (GO:1903312)2.87341233
134histone arginine methylation (GO:0034969)2.84725770
135Golgi transport vesicle coating (GO:0048200)2.84588786
136COPI coating of Golgi vesicle (GO:0048205)2.84588786
137SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.79282640
138viral life cycle (GO:0019058)2.79157685
139nucleosome disassembly (GO:0006337)2.77973013
140protein-DNA complex disassembly (GO:0032986)2.77973013
141maternal placenta development (GO:0001893)2.75943220
142folic acid-containing compound biosynthetic process (GO:0009396)2.75171383
143cotranslational protein targeting to membrane (GO:0006613)2.74909196
144cellular protein complex disassembly (GO:0043624)2.74451220
145chromatin assembly or disassembly (GO:0006333)2.74259991
146negative regulation of RNA splicing (GO:0033119)2.72984023
147protein targeting to ER (GO:0045047)2.71655823
148protein complex disassembly (GO:0043241)2.70344097
149regulation of chromatin binding (GO:0035561)2.68919923
150chromatin assembly (GO:0031497)2.68340464
151nuclear envelope reassembly (GO:0031468)2.67191964
152mitotic nuclear envelope reassembly (GO:0007084)2.67191964
153apoptotic process involved in morphogenesis (GO:0060561)2.65997333
154ncRNA 3-end processing (GO:0043628)2.64831506
155positive regulation of DNA-dependent DNA replication (GO:2000105)2.64155469
156regulation of mitochondrial translation (GO:0070129)2.63940736
157L-serine metabolic process (GO:0006563)2.61005600
158establishment of apical/basal cell polarity (GO:0035089)2.60566890
159establishment of protein localization to endoplasmic reticulum (GO:0072599)2.59739965
160peptidyl-arginine methylation (GO:0018216)2.58452744

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.41556779
2FOXM1_23109430_ChIP-Seq_U2OS_Human6.47959475
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.06992648
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.94563733
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.87255537
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.49710164
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.29489919
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.06999805
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.01982722
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.95093821
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.92375804
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.84830574
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.84785681
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.84642324
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80691669
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.63908241
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.47227488
18XRN2_22483619_ChIP-Seq_HELA_Human2.43849963
19AR_21909140_ChIP-Seq_LNCAP_Human2.42702448
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.25729690
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.22197427
22VDR_23849224_ChIP-Seq_CD4+_Human2.16814192
23TP63_17297297_ChIP-ChIP_HaCaT_Human2.06421801
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.06256755
25MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03051914
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.01774399
27NANOG_18555785_ChIP-Seq_MESCs_Mouse2.01600087
28E2F1_21310950_ChIP-Seq_MCF-7_Human1.91076035
29DCP1A_22483619_ChIP-Seq_HELA_Human1.89570296
30FOXP3_21729870_ChIP-Seq_TREG_Human1.88752360
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88089582
32GABP_19822575_ChIP-Seq_HepG2_Human1.87892533
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.87280433
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.85661591
35ESR1_15608294_ChIP-ChIP_MCF-7_Human1.83632058
36CIITA_25753668_ChIP-Seq_RAJI_Human1.83355060
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.81493599
38TTF2_22483619_ChIP-Seq_HELA_Human1.78929665
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78903649
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.77893736
41RACK7_27058665_Chip-Seq_MCF-7_Human1.76559873
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75742106
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.70329113
44KDM5A_27292631_Chip-Seq_BREAST_Human1.61384572
45PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.59103660
46KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.58176982
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53595410
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50540592
49ELF1_17652178_ChIP-ChIP_JURKAT_Human1.49241533
50MYC_22102868_ChIP-Seq_BL_Human1.49096514
51LXR_22292898_ChIP-Seq_THP-1_Human1.48964662
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.48008209
53TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.46894598
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46463985
55SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.43853301
56EGR1_19374776_ChIP-ChIP_THP-1_Human1.43649329
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40825110
58ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.37827607
59FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37053620
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36201847
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.31319054
62KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.30901802
63TET1_21451524_ChIP-Seq_MESCs_Mouse1.30416339
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.29859289
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.29287609
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.27270684
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.27080780
68POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26487733
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24201991
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.23143646
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.22309641
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22173833
73KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.21854915
74SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.21697010
75ELK1_19687146_ChIP-ChIP_HELA_Human1.21263226
76KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18208388
77SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16227354
78ATF3_27146783_Chip-Seq_COLON_Human1.15325486
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14665243
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14623726
81ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.13861959
82SRF_21415370_ChIP-Seq_HL-1_Mouse1.13723978
83HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.13594959
84STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12281939
85CHD1_26751641_Chip-Seq_LNCaP_Human1.11860568
86CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11854324
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.11758619
88SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10630655
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10553373
90NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.10538584
91SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.09490259
92EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09362740
93P68_20966046_ChIP-Seq_HELA_Human1.08882041
94PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05925050
95NANOG_21062744_ChIP-ChIP_HESCs_Human1.01929177
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01294724
97VDR_21846776_ChIP-Seq_THP-1_Human1.01172469
98ZNF263_19887448_ChIP-Seq_K562_Human1.00335067
99PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.99198942
100ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.98164428
101KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.97769367
102TCF7_22412390_ChIP-Seq_EML_Mouse0.97521307
103ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96885928
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.96435336
105PKCTHETA_26484144_Chip-Seq_BREAST_Human0.94442340
106HIF1A_21447827_ChIP-Seq_MCF-7_Human0.94271070
107CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.93469523
108FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93321808
109NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.93219694
110CREB1_26743006_Chip-Seq_LNCaP_Human0.92821107
111RUNX1_27514584_Chip-Seq_MCF-7_Human0.92724248
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92205021
113ERG_21242973_ChIP-ChIP_JURKAT_Human0.91982293
114TBX5_21415370_ChIP-Seq_HL-1_Mouse0.91407031
115TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.90832772
116TFEB_21752829_ChIP-Seq_HELA_Human0.89793650
117UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.89573214
118ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88615874
119ELK1_22589737_ChIP-Seq_MCF10A_Human0.88146436
120BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83441306
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.82486175
122SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81376301
123OCT4_18692474_ChIP-Seq_MEFs_Mouse0.80912905
124TCF3_18692474_ChIP-Seq_MEFs_Mouse0.80854791
125MYC_18940864_ChIP-ChIP_HL60_Human0.78926520
126TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.77290467
127NOTCH1_21737748_ChIP-Seq_TLL_Human0.76931687
128FOXP1_21924763_ChIP-Seq_HESCs_Human0.76223575
129POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.75654695
130SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.75361476
131TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.73646545
132NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.73579356
133TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.72925592

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.98539930
2MP0003111_abnormal_nucleus_morphology5.71230844
3MP0004957_abnormal_blastocyst_morpholog4.63488036
4MP0003077_abnormal_cell_cycle4.43977111
5MP0010094_abnormal_chromosome_stability4.41764161
6MP0010234_abnormal_vibrissa_follicle4.25690497
7MP0008057_abnormal_DNA_replication3.14786728
8MP0003705_abnormal_hypodermis_morpholog3.00682857
9MP0008058_abnormal_DNA_repair3.00152235
10MP0008932_abnormal_embryonic_tissue2.92135649
11MP0008007_abnormal_cellular_replicative2.70449962
12MP0003718_maternal_effect2.56841122
13MP0001730_embryonic_growth_arrest2.50348706
14MP0004185_abnormal_adipocyte_glucose2.32515224
15MP0003786_premature_aging2.27584302
16MP0002796_impaired_skin_barrier2.26569758
17MP0000350_abnormal_cell_proliferation2.24589452
18MP0005451_abnormal_body_composition2.24275236
19MP0005501_abnormal_skin_physiology2.07885363
20MP0003123_paternal_imprinting2.06628482
21MP0002877_abnormal_melanocyte_morpholog2.01610860
22MP0005380_embryogenesis_phenotype1.94932866
23MP0001672_abnormal_embryogenesis/_devel1.94932866
24MP0002396_abnormal_hematopoietic_system1.85033909
25MP0009379_abnormal_foot_pigmentation1.84582203
26MP0005377_hearing/vestibular/ear_phenot1.83110354
27MP0003878_abnormal_ear_physiology1.83110354
28MP0010307_abnormal_tumor_latency1.80805748
29MP0001697_abnormal_embryo_size1.80089228
30MP0010030_abnormal_orbit_morphology1.79684778
31MP0004233_abnormal_muscle_weight1.71253905
32MP0008260_abnormal_autophagy1.69742174
33MP0002080_prenatal_lethality1.69625898
34MP0002098_abnormal_vibrissa_morphology1.68711685
35MP0004264_abnormal_extraembryonic_tissu1.67222959
36MP0002085_abnormal_embryonic_tissue1.66827959
37MP0003984_embryonic_growth_retardation1.64948106
38MP0002088_abnormal_embryonic_growth/wei1.61613371
39MP0001346_abnormal_lacrimal_gland1.59443728
40MP0002249_abnormal_larynx_morphology1.57200355
41MP0008877_abnormal_DNA_methylation1.49531447
42MP0000490_abnormal_crypts_of1.47246656
43MP0002653_abnormal_ependyma_morphology1.44160014
44MP0000313_abnormal_cell_death1.43810491
45MP0003938_abnormal_ear_development1.43441877
46MP0002084_abnormal_developmental_patter1.39399215
47MP0000678_abnormal_parathyroid_gland1.38760628
48MP0003453_abnormal_keratinocyte_physiol1.36396445
49MP0009333_abnormal_splenocyte_physiolog1.36077164
50MP0002102_abnormal_ear_morphology1.32831746
51MP0002086_abnormal_extraembryonic_tissu1.32594182
52MP0003567_abnormal_fetal_cardiomyocyte1.30072564
53MP0003941_abnormal_skin_development1.29259130
54MP0003942_abnormal_urinary_system1.27414298
55MP0002697_abnormal_eye_size1.27095593
56MP0002019_abnormal_tumor_incidence1.26293817
57MP0000579_abnormal_nail_morphology1.25784850
58MP0009840_abnormal_foam_cell1.24874972
59MP0001545_abnormal_hematopoietic_system1.24581202
60MP0005397_hematopoietic_system_phenotyp1.24581202
61MP0001849_ear_inflammation1.22931621
62MP0004858_abnormal_nervous_system1.22394016
63MP0003315_abnormal_perineum_morphology1.21834838
64MP0002210_abnormal_sex_determination1.20838812
65MP0009278_abnormal_bone_marrow1.19164616
66MP0004808_abnormal_hematopoietic_stem1.17088506
67MP0010352_gastrointestinal_tract_polyps1.16294161
68MP0004782_abnormal_surfactant_physiolog1.13453527
69MP0010678_abnormal_skin_adnexa1.12985260
70MP0001293_anophthalmia1.12059469
71MP0006292_abnormal_olfactory_placode1.11189880
72MP0000566_synostosis1.09679595
73MP0003119_abnormal_digestive_system1.08363187
74MP0001145_abnormal_male_reproductive1.07724893
75MP0005257_abnormal_intraocular_pressure1.07409837
76MP0003937_abnormal_limbs/digits/tail_de1.05204460
77MP0005666_abnormal_adipose_tissue1.04622038
78MP0002132_abnormal_respiratory_system1.03885222
79MP0004197_abnormal_fetal_growth/weight/1.01361001
80MP0001348_abnormal_lacrimal_gland1.00473079
81MP0001929_abnormal_gametogenesis0.99823153
82MP0000467_abnormal_esophagus_morphology0.99371881
83MP0000377_abnormal_hair_follicle0.99241605
84MP0002089_abnormal_postnatal_growth/wei0.98643068
85MP0001216_abnormal_epidermal_layer0.98107147
86MP0000428_abnormal_craniofacial_morphol0.97576994
87MP0000762_abnormal_tongue_morphology0.97520221
88MP0009672_abnormal_birth_weight0.96351261
89MP0002111_abnormal_tail_morphology0.94100807
90MP0000627_abnormal_mammary_gland0.93842250
91MP0000703_abnormal_thymus_morphology0.92905351
92MP0000462_abnormal_digestive_system0.92811315
93MP0005076_abnormal_cell_differentiation0.92179055
94MP0009053_abnormal_anal_canal0.91821362
95MP0000537_abnormal_urethra_morphology0.89407838
96MP0000534_abnormal_ureter_morphology0.89381156
97MP0000653_abnormal_sex_gland0.89103730
98MP0005389_reproductive_system_phenotype0.88455546
99MP0010771_integument_phenotype0.87022941
100MP0005409_darkened_coat_color0.83726568
101MP0003221_abnormal_cardiomyocyte_apopto0.83415701
102MP0001919_abnormal_reproductive_system0.81861435
103MP0002160_abnormal_reproductive_system0.81703958
104MP0002722_abnormal_immune_system0.81252256
105MP0001881_abnormal_mammary_gland0.80227150
106MP0002060_abnormal_skin_morphology0.80062856
107MP0001727_abnormal_embryo_implantation0.77543200
108MP0003890_abnormal_embryonic-extraembry0.77458123
109MP0002092_abnormal_eye_morphology0.75656921
110MP0000477_abnormal_intestine_morphology0.75190377
111MP0005621_abnormal_cell_physiology0.73507141
112MP0001873_stomach_inflammation0.72937989
113MP0000358_abnormal_cell_content/0.72150094
114MP0006035_abnormal_mitochondrial_morpho0.72068517
115MP0001340_abnormal_eyelid_morphology0.71209384
116MP0003566_abnormal_cell_adhesion0.70952343
117MP0001286_abnormal_eye_development0.70080032
118MP0005384_cellular_phenotype0.69956064
119MP0001119_abnormal_female_reproductive0.69207709
120MP0003385_abnormal_body_wall0.68463746
121MP0000049_abnormal_middle_ear0.68303591
122MP0000689_abnormal_spleen_morphology0.68009018
123MP0000750_abnormal_muscle_regeneration0.67916527
124MP0002398_abnormal_bone_marrow0.67465592
125MP0002751_abnormal_autonomic_nervous0.67098076
126MP0001661_extended_life_span0.66059041
127MP0009703_decreased_birth_body0.65554486
128MP0005395_other_phenotype0.64055837
129MP0003699_abnormal_female_reproductive0.63763620
130MP0003136_yellow_coat_color0.63756581
131MP0003115_abnormal_respiratory_system0.63152935
132MP0000383_abnormal_hair_follicle0.62536828
133MP0008995_early_reproductive_senescence0.62373025
134MP0002938_white_spotting0.61970262
135MP0003861_abnormal_nervous_system0.60887384
136MP0002163_abnormal_gland_morphology0.58778398
137MP0002932_abnormal_joint_morphology0.57488080
138MP0003935_abnormal_craniofacial_develop0.57174692
139MP0003121_genomic_imprinting0.56346860
140MP0000733_abnormal_muscle_development0.55598583
141MP0008789_abnormal_olfactory_epithelium0.54293023
142MP0002161_abnormal_fertility/fecundity0.53822293
143MP0002114_abnormal_axial_skeleton0.53427066
144MP0002429_abnormal_blood_cell0.52178444

Predicted human phenotypes

RankGene SetZ-score
1Breast hypoplasia (HP:0003187)4.70527427
2Birth length less than 3rd percentile (HP:0003561)4.65317633
3Patellar aplasia (HP:0006443)4.07996408
4Carpal bone hypoplasia (HP:0001498)4.05615718
5Aplasia/Hypoplasia of the patella (HP:0006498)3.98228076
6Cerebral hypomyelination (HP:0006808)3.91481744
7Reticulocytopenia (HP:0001896)3.91044879
8Impulsivity (HP:0100710)3.75655277
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.67452511
10Hyperacusis (HP:0010780)3.66556297
11Rough bone trabeculation (HP:0100670)3.63648845
12Septate vagina (HP:0001153)3.60615732
13Chromsome breakage (HP:0040012)3.48044545
14Absent radius (HP:0003974)3.44826904
15Aplasia/Hypoplasia of the sacrum (HP:0008517)3.43318742
16Oral leukoplakia (HP:0002745)3.37895013
17Abnormality of cells of the erythroid lineage (HP:0012130)3.33215434
18Absent forearm bone (HP:0003953)3.32419191
19Aplasia involving forearm bones (HP:0009822)3.32419191
20Abnormal number of erythroid precursors (HP:0012131)3.20081705
21Abnormality of the preputium (HP:0100587)3.17141430
22Meckel diverticulum (HP:0002245)3.10962855
23Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.10389868
24Asymmetry of the thorax (HP:0001555)2.99791414
25Abnormality of the ileum (HP:0001549)2.93971508
26Macrocytic anemia (HP:0001972)2.82788370
27Ulnar bowing (HP:0003031)2.81493099
28Aplasia/Hypoplasia of the uvula (HP:0010293)2.80989866
29Duodenal stenosis (HP:0100867)2.76177565
30Small intestinal stenosis (HP:0012848)2.76177565
31Abnormality of chromosome stability (HP:0003220)2.71968548
32Premature ovarian failure (HP:0008209)2.70503504
33Absent thumb (HP:0009777)2.65818593
34Hypoplasia of the capital femoral epiphysis (HP:0003090)2.62909195
35Ureteral duplication (HP:0000073)2.59586422
36Insomnia (HP:0100785)2.59561566
37Horseshoe kidney (HP:0000085)2.58864598
38Trismus (HP:0000211)2.58721261
39Multiple enchondromatosis (HP:0005701)2.56857166
40Secondary amenorrhea (HP:0000869)2.53534982
41Abnormal trabecular bone morphology (HP:0100671)2.52346906
42Oligodactyly (HP:0012165)2.50540393
43Entropion (HP:0000621)2.49248676
44Abnormality of the anterior horn cell (HP:0006802)2.46771829
45Degeneration of anterior horn cells (HP:0002398)2.46771829
46Selective tooth agenesis (HP:0001592)2.46518881
47Microvesicular hepatic steatosis (HP:0001414)2.45499332
48Progressive muscle weakness (HP:0003323)2.44197436
49Colon cancer (HP:0003003)2.43199915
50Abnormality of the umbilical cord (HP:0010881)2.42769228
51Bone marrow hypocellularity (HP:0005528)2.42183604
52Neoplasm of the pancreas (HP:0002894)2.41881161
53Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.41239338
54Absent epiphyses (HP:0010577)2.41239338
55Glossoptosis (HP:0000162)2.40138362
56Pili torti (HP:0003777)2.39190848
57Deviation of the thumb (HP:0009603)2.38109350
58Triphalangeal thumb (HP:0001199)2.37583924
59Testicular atrophy (HP:0000029)2.36457298
60Broad distal phalanx of finger (HP:0009836)2.36236996
61Elfin facies (HP:0004428)2.35114157
62Microretrognathia (HP:0000308)2.34663447
63Pallor (HP:0000980)2.33611072
64Medulloblastoma (HP:0002885)2.33060786
65Small epiphyses (HP:0010585)2.29360326
66Duplication of thumb phalanx (HP:0009942)2.28755514
67Myelodysplasia (HP:0002863)2.28500668
68Overriding aorta (HP:0002623)2.28380707
69Aplasia/Hypoplasia of the earlobes (HP:0009906)2.27270752
70Abnormality of the duodenum (HP:0002246)2.27051654
71High anterior hairline (HP:0009890)2.25684731
72Premature graying of hair (HP:0002216)2.25188716
73Atresia of the external auditory canal (HP:0000413)2.24218485
74Abnormality of the labia minora (HP:0012880)2.22959672
75Tracheoesophageal fistula (HP:0002575)2.21394334
76Short middle phalanx of the 5th finger (HP:0004220)2.17189818
77Hypoplasia of the radius (HP:0002984)2.16381173
78Sloping forehead (HP:0000340)2.14409849
7911 pairs of ribs (HP:0000878)2.12954956
80Microglossia (HP:0000171)2.11576064
81Oligodactyly (hands) (HP:0001180)2.11416856
82Cellular immunodeficiency (HP:0005374)2.11195845
83Missing ribs (HP:0000921)2.10703521
84Abnormality of reticulocytes (HP:0004312)2.09632001
85Ependymoma (HP:0002888)2.08511733
86Progressive external ophthalmoplegia (HP:0000590)2.08101708
87Cleft eyelid (HP:0000625)2.06929325
88Irregular epiphyses (HP:0010582)2.06156012
89CNS hypomyelination (HP:0003429)2.03659848
90Patellar dislocation (HP:0002999)2.03400720
91Increased nuchal translucency (HP:0010880)2.03350761
92Short thumb (HP:0009778)2.02632494
93Abnormal lung lobation (HP:0002101)1.99968936
94Hyperglycinemia (HP:0002154)1.99648974
95Achilles tendon contracture (HP:0001771)1.99245490
96Ragged-red muscle fibers (HP:0003200)1.97155618
97Abnormal number of incisors (HP:0011064)1.96466110
98Sparse lateral eyebrow (HP:0005338)1.95643807
99Aplasia/Hypoplasia of the sternum (HP:0006714)1.95540701
100Vaginal fistula (HP:0004320)1.94039398
101Personality changes (HP:0000751)1.93655570
102Ectopic kidney (HP:0000086)1.91282166
103Abnormality of the phalanges of the hallux (HP:0010057)1.91202330
104Hypoparathyroidism (HP:0000829)1.90233310
105Renal duplication (HP:0000075)1.90062364
106Abnormality of the distal phalanx of the thumb (HP:0009617)1.89904849
107Self-mutilation (HP:0000742)1.89099277
108Duplicated collecting system (HP:0000081)1.86784078
109Sparse eyelashes (HP:0000653)1.85996641
110Cafe-au-lait spot (HP:0000957)1.85827074
111Micronodular cirrhosis (HP:0001413)1.85741482
112Facial hemangioma (HP:0000329)1.84490850
113Rhabdomyosarcoma (HP:0002859)1.83967700
114Abnormality of the carotid arteries (HP:0005344)1.82910452
115Megaloblastic anemia (HP:0001889)1.81978770
116Squamous cell carcinoma (HP:0002860)1.81596026
117Prominent nose (HP:0000448)1.81371953
118Broad face (HP:0000283)1.80535948
119Abnormality of the distal phalanges of the toes (HP:0010182)1.80198633
120Concave nail (HP:0001598)1.79834625
121Aplastic anemia (HP:0001915)1.79381565
122Choanal atresia (HP:0000453)1.79184355
123Flat acetabular roof (HP:0003180)1.78963616
124Congenital, generalized hypertrichosis (HP:0004540)1.75954501
125Pustule (HP:0200039)1.73849764
126Abnormality of the Achilles tendon (HP:0005109)1.73580660
127Progressive hearing impairment (HP:0001730)1.72573031
128Truncus arteriosus (HP:0001660)1.72218919
129Long palpebral fissure (HP:0000637)1.71414411
130Ankyloglossia (HP:0010296)1.71101447
131Aplasia/Hypoplasia involving the musculature (HP:0001460)1.70507000
132Intestinal fistula (HP:0100819)1.70023664
133Short nail (HP:0001799)1.69584419
134Pelvic girdle muscle weakness (HP:0003749)1.69583722
135Partial duplication of thumb phalanx (HP:0009944)1.69165856
136Atrophy/Degeneration involving motor neurons (HP:0007373)1.68805076
137Germ cell neoplasia (HP:0100728)1.68393298
138Supernumerary spleens (HP:0009799)1.68098581
139Aplasia/Hypoplasia of the breasts (HP:0010311)1.67918478
140Poikiloderma (HP:0001029)1.66682185
141Abnormal umbilical cord blood vessels (HP:0011403)1.66562959
142Single umbilical artery (HP:0001195)1.66562959
143Abnormality of the fetal cardiovascular system (HP:0010948)1.66562959
144Breast aplasia (HP:0100783)1.66375021
145Dysmetric saccades (HP:0000641)1.66207230
146Abnormalities of placenta or umbilical cord (HP:0001194)1.66042827
147Overlapping toe (HP:0001845)1.65603465
148Hyperthyroidism (HP:0000836)1.65342953
149Proximal placement of thumb (HP:0009623)1.65136417
150Abnormality of glycolysis (HP:0004366)1.64601099
151Spinal cord compression (HP:0002176)1.63511747
152Abnormal hair laboratory examination (HP:0003328)1.62094576
153Rectal fistula (HP:0100590)1.61431852
154Rectovaginal fistula (HP:0000143)1.61431852
155Abnormality of cochlea (HP:0000375)1.60805071
156Preauricular skin tag (HP:0000384)1.60381292
157Thin bony cortex (HP:0002753)1.60338688
158Abnormality of the gastric mucosa (HP:0004295)1.60062040
159Partial duplication of the phalanx of hand (HP:0009999)1.59931461

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB18.02576091
2WEE14.63636842
3NEK23.60238458
4SMG13.48520562
5SIK13.15540007
6BRSK12.81640726
7BRSK22.68342047
8PLK42.68123392
9TTK2.64012122
10MST1R2.61530278
11EIF2AK12.55689960
12STK162.43469998
13CDC72.42486662
14ICK2.31143638
15PLK12.25736342
16SRPK12.17186081
17TSSK62.12982299
18PKN22.09415007
19TLK12.03661429
20VRK21.85221870
21AURKB1.80723114
22DYRK31.79122989
23TESK21.76521231
24EPHA21.76098623
25AURKA1.75665192
26MKNK21.66082813
27CCNB11.65613994
28PLK31.63748407
29NME21.63685886
30NEK11.58844270
31MKNK11.52844401
32CHEK21.51903756
33IRAK21.44450095
34EIF2AK31.43403119
35ZAK1.41464846
36STK101.40749071
37MAP3K81.38235103
38CDK71.32758015
39CDK41.32351267
40VRK11.31681996
41AKT31.30874019
42ACVR1B1.29863862
43MELK1.27488726
44RPS6KA41.26758199
45ATR1.15307342
46MAP3K101.10908545
47CHEK11.09603151
48STK41.05680868
49MET1.02337125
50LMTK21.00743450
51BRAF0.98032918
52RPS6KB20.91456249
53ILK0.89539383
54PAK10.86499861
55PTK60.85974872
56FGFR40.82962264
57PRPF4B0.80523467
58PAK40.77544839
59EEF2K0.76749473
60CDK20.75864544
61PRKCI0.75290237
62TAF10.72792275
63PRKD30.72592311
64ARAF0.70282129
65PNCK0.68708301
66PTK20.67173154
67STK30.67138255
68CDK10.62065893
69EIF2AK20.61905297
70MAPK110.61052028
71AKT20.59070942
72UHMK10.58854367
73TESK10.58346548
74CAMK1D0.58111794
75IRAK30.57171712
76PIM10.56786930
77MARK30.56646614
78ATM0.55772654
79ALK0.55763707
80PASK0.53822326
81CDK80.53113816
82BMX0.52929372
83CSNK2A10.52668859
84TTN0.52091619
85MAP3K90.52087962
86CSNK2A20.51349679
87STK390.49701239
88MUSK0.49648479
89RPS6KA50.46720712
90IRAK40.46110704
91PIM20.44583691
92MAP4K10.43966779
93CDK120.41864092
94RIPK10.41107003
95DDR20.40085880
96TRIB30.38478118
97NME10.38471225
98MAP3K110.37615431
99ERBB40.37364727
100KDR0.36592087
101PDGFRA0.35921118
102CDK60.35101540
103WNK40.34280463
104PDPK10.33845521
105LATS20.32565428
106DMPK0.31664750
107TAOK10.30453688
108CSNK1E0.30174976
109NEK60.28826485
110CDK150.28818080
111RPS6KB10.28749987
112MTOR0.27561692
113MAP2K20.27225204
114DYRK20.26957149
115MAPKAPK20.26388205
116DYRK1B0.25626350
117RPS6KA10.22593537
118SCYL20.22349392
119PBK0.21889730
120CLK10.21646888
121LRRK20.21355192
122TAOK20.20333408
123GRK60.19546574
124CSNK1G30.18700770
125MAPKAPK30.18343677
126PDK30.18230553
127PDK40.18230553
128BRD40.17619999
129MAPK90.16631448
130PRKDC0.16507527
131BCKDK0.15536613
132CDK11A0.14903239
133BLK0.13427559
134CSNK1G10.13414890
135STK38L0.13083755

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.35911265
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.85473098
3RNA polymerase_Homo sapiens_hsa030203.81440444
4Mismatch repair_Homo sapiens_hsa034303.53180844
5Spliceosome_Homo sapiens_hsa030403.50122381
6Vitamin B6 metabolism_Homo sapiens_hsa007503.39131144
7RNA transport_Homo sapiens_hsa030133.31893997
8Proteasome_Homo sapiens_hsa030503.30225045
9Ribosome_Homo sapiens_hsa030103.26049781
10Cell cycle_Homo sapiens_hsa041103.22877648
11Base excision repair_Homo sapiens_hsa034103.17192509
12Homologous recombination_Homo sapiens_hsa034402.85472115
13Pyrimidine metabolism_Homo sapiens_hsa002402.58736826
14Nucleotide excision repair_Homo sapiens_hsa034202.55189264
15Fanconi anemia pathway_Homo sapiens_hsa034602.32914925
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.95689226
17Basal transcription factors_Homo sapiens_hsa030221.94520616
18p53 signaling pathway_Homo sapiens_hsa041151.87149875
19One carbon pool by folate_Homo sapiens_hsa006701.85922228
20mRNA surveillance pathway_Homo sapiens_hsa030151.75962991
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.71457796
22Folate biosynthesis_Homo sapiens_hsa007901.67847624
23Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.56305543
24RNA degradation_Homo sapiens_hsa030181.55192223
25Oocyte meiosis_Homo sapiens_hsa041141.45547730
26Purine metabolism_Homo sapiens_hsa002301.45268017
27Non-homologous end-joining_Homo sapiens_hsa034501.42994449
28Epstein-Barr virus infection_Homo sapiens_hsa051691.26725485
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.26213890
30Sulfur relay system_Homo sapiens_hsa041221.21168180
31Pentose phosphate pathway_Homo sapiens_hsa000301.20506086
32Systemic lupus erythematosus_Homo sapiens_hsa053221.15283742
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05372012
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03451648
35Endometrial cancer_Homo sapiens_hsa052131.03181921
36Regulation of autophagy_Homo sapiens_hsa041400.96778327
37Pyruvate metabolism_Homo sapiens_hsa006200.96358561
38Drug metabolism - other enzymes_Homo sapiens_hsa009830.96122834
39Lysine degradation_Homo sapiens_hsa003100.94947497
40Fatty acid biosynthesis_Homo sapiens_hsa000610.93959342
41Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90255025
42Cysteine and methionine metabolism_Homo sapiens_hsa002700.86359000
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84655227
44Steroid biosynthesis_Homo sapiens_hsa001000.82733617
45Viral carcinogenesis_Homo sapiens_hsa052030.82069511
46AMPK signaling pathway_Homo sapiens_hsa041520.79892477
47Biosynthesis of amino acids_Homo sapiens_hsa012300.79124217
48Pancreatic cancer_Homo sapiens_hsa052120.79058401
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75510051
50Herpes simplex infection_Homo sapiens_hsa051680.74068360
51HTLV-I infection_Homo sapiens_hsa051660.72776076
52Insulin signaling pathway_Homo sapiens_hsa049100.66643186
53Notch signaling pathway_Homo sapiens_hsa043300.66094384
54Glioma_Homo sapiens_hsa052140.66078974
55Arginine biosynthesis_Homo sapiens_hsa002200.65163041
56Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63725599
57MicroRNAs in cancer_Homo sapiens_hsa052060.63137792
58Basal cell carcinoma_Homo sapiens_hsa052170.62817997
59VEGF signaling pathway_Homo sapiens_hsa043700.62774179
60Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62758062
61Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61292135
62Vibrio cholerae infection_Homo sapiens_hsa051100.60267466
63ErbB signaling pathway_Homo sapiens_hsa040120.59096970
64Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57470911
65Hippo signaling pathway_Homo sapiens_hsa043900.57150310
66Antigen processing and presentation_Homo sapiens_hsa046120.56159066
67Small cell lung cancer_Homo sapiens_hsa052220.52438849
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52408976
69Fructose and mannose metabolism_Homo sapiens_hsa000510.51392517
70Glycerophospholipid metabolism_Homo sapiens_hsa005640.50074892
71Hedgehog signaling pathway_Homo sapiens_hsa043400.49902617
72Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49723233
73Selenocompound metabolism_Homo sapiens_hsa004500.49588589
74Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.48818843
75Renal cell carcinoma_Homo sapiens_hsa052110.48142140
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.47226452
77Vitamin digestion and absorption_Homo sapiens_hsa049770.46365313
78Cyanoamino acid metabolism_Homo sapiens_hsa004600.45091912
79Adherens junction_Homo sapiens_hsa045200.41892126
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41560713
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41351154
82Alcoholism_Homo sapiens_hsa050340.39417706
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.38808738
84Primary immunodeficiency_Homo sapiens_hsa053400.38622976
85Proteoglycans in cancer_Homo sapiens_hsa052050.38003140
86Glutathione metabolism_Homo sapiens_hsa004800.36457856
87Apoptosis_Homo sapiens_hsa042100.35996382
88Bladder cancer_Homo sapiens_hsa052190.35290480
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34202891
90Thyroid cancer_Homo sapiens_hsa052160.34081644
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.33885862
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33084443
93mTOR signaling pathway_Homo sapiens_hsa041500.31214367
94FoxO signaling pathway_Homo sapiens_hsa040680.30996281
95Carbon metabolism_Homo sapiens_hsa012000.29994477
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29213014
97N-Glycan biosynthesis_Homo sapiens_hsa005100.27453253
98Colorectal cancer_Homo sapiens_hsa052100.26807859
99Huntingtons disease_Homo sapiens_hsa050160.25894430
100Hepatitis B_Homo sapiens_hsa051610.25779404
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24499786
102Renin-angiotensin system_Homo sapiens_hsa046140.24353136
103Metabolic pathways_Homo sapiens_hsa011000.24229807
104TGF-beta signaling pathway_Homo sapiens_hsa043500.23913576
105Chronic myeloid leukemia_Homo sapiens_hsa052200.23446292
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.18331340
107Pathways in cancer_Homo sapiens_hsa052000.17100111
108Intestinal immune network for IgA production_Homo sapiens_hsa046720.16945455
1092-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.16373811
110HIF-1 signaling pathway_Homo sapiens_hsa040660.16340864
111Galactose metabolism_Homo sapiens_hsa000520.15574493
112Legionellosis_Homo sapiens_hsa051340.13642337
113Prostate cancer_Homo sapiens_hsa052150.13532086
114Wnt signaling pathway_Homo sapiens_hsa043100.13465692
115Arginine and proline metabolism_Homo sapiens_hsa003300.11293864
116Protein export_Homo sapiens_hsa030600.11187123
117Central carbon metabolism in cancer_Homo sapiens_hsa052300.11110630
118Tight junction_Homo sapiens_hsa045300.08417343
119Measles_Homo sapiens_hsa051620.08313791
120Acute myeloid leukemia_Homo sapiens_hsa052210.07663425
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.06944880
122NF-kappa B signaling pathway_Homo sapiens_hsa040640.06475617
123Non-small cell lung cancer_Homo sapiens_hsa052230.05885872
124Circadian rhythm_Homo sapiens_hsa047100.05724670
125Influenza A_Homo sapiens_hsa051640.05199275
126Melanoma_Homo sapiens_hsa052180.04599973
127Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.04435888

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