SARM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to synapse (GO:0035418)5.50125757
2neuron cell-cell adhesion (GO:0007158)5.47463270
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.37025500
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.27431107
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.05152473
6vocalization behavior (GO:0071625)5.04768012
7response to pheromone (GO:0019236)5.03491614
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.83712976
9synaptic vesicle exocytosis (GO:0016079)4.71689350
10synaptic vesicle maturation (GO:0016188)4.61214704
11regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.58758581
12pyrimidine nucleobase catabolic process (GO:0006208)4.57459909
13postsynaptic membrane organization (GO:0001941)4.54640543
14regulation of synaptic vesicle exocytosis (GO:2000300)4.34962201
15cell migration in hindbrain (GO:0021535)4.19498115
16regulation of glutamate receptor signaling pathway (GO:1900449)4.19333018
17dendritic spine morphogenesis (GO:0060997)4.08744170
18layer formation in cerebral cortex (GO:0021819)4.07894712
19regulation of rhodopsin mediated signaling pathway (GO:0022400)4.05700216
20exploration behavior (GO:0035640)3.98908954
21neuronal action potential propagation (GO:0019227)3.94747711
22rhodopsin mediated signaling pathway (GO:0016056)3.92531635
23locomotory exploration behavior (GO:0035641)3.86837948
24glutamate secretion (GO:0014047)3.83689228
25ionotropic glutamate receptor signaling pathway (GO:0035235)3.82302514
26neuron recognition (GO:0008038)3.82154435
27regulation of synaptic vesicle transport (GO:1902803)3.79556940
28negative regulation of microtubule polymerization (GO:0031115)3.73295370
29positive regulation of membrane potential (GO:0045838)3.69786460
30retinal cone cell development (GO:0046549)3.68720360
31glutamate receptor signaling pathway (GO:0007215)3.67048167
32presynaptic membrane assembly (GO:0097105)3.66720980
33central nervous system projection neuron axonogenesis (GO:0021952)3.66547442
34axonal fasciculation (GO:0007413)3.58078149
35synaptic vesicle docking involved in exocytosis (GO:0016081)3.57762970
36synaptic transmission, glutamatergic (GO:0035249)3.57525651
37neurotransmitter secretion (GO:0007269)3.54819791
38regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.54312681
39nucleobase catabolic process (GO:0046113)3.53796600
40neurotransmitter-gated ion channel clustering (GO:0072578)3.53261752
41regulation of synapse structural plasticity (GO:0051823)3.52123138
42positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.49202935
43positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.45223657
44positive regulation of synaptic transmission, GABAergic (GO:0032230)3.45012392
45righting reflex (GO:0060013)3.44013237
46detection of light stimulus involved in sensory perception (GO:0050962)3.43726019
47detection of light stimulus involved in visual perception (GO:0050908)3.43726019
48neuron-neuron synaptic transmission (GO:0007270)3.43699925
49membrane hyperpolarization (GO:0060081)3.43318092
50regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.43170107
51regulation of neuronal synaptic plasticity (GO:0048168)3.41327793
52auditory behavior (GO:0031223)3.40711530
53positive regulation of synapse maturation (GO:0090129)3.38138255
54response to auditory stimulus (GO:0010996)3.33909473
55innervation (GO:0060384)3.33629524
56neurofilament cytoskeleton organization (GO:0060052)3.33284512
57presynaptic membrane organization (GO:0097090)3.31662249
58retinal rod cell development (GO:0046548)3.30154687
59positive regulation of dendritic spine development (GO:0060999)3.30102498
60cerebellar Purkinje cell differentiation (GO:0021702)3.29184308
61regulation of postsynaptic membrane potential (GO:0060078)3.28664889
62regulation of respiratory system process (GO:0044065)3.25846416
63regulation of excitatory postsynaptic membrane potential (GO:0060079)3.24497287
64neurotransmitter transport (GO:0006836)3.24330484
65histone H3-K4 trimethylation (GO:0080182)3.24305070
66positive regulation of neurotransmitter transport (GO:0051590)3.23610864
67photoreceptor cell development (GO:0042461)3.22204416
68cranial nerve morphogenesis (GO:0021602)3.20245612
69synapse assembly (GO:0007416)3.17990154
70G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.15727985
71regulation of neurotransmitter secretion (GO:0046928)3.15585636
72neuromuscular process controlling posture (GO:0050884)3.14924241
73positive regulation of neurotransmitter secretion (GO:0001956)3.14169308
74positive regulation of dendritic spine morphogenesis (GO:0061003)3.14126071
75long-term memory (GO:0007616)3.13724357
76regulation of respiratory gaseous exchange (GO:0043576)3.13231673
77establishment of nucleus localization (GO:0040023)3.11180374
78cellular potassium ion homeostasis (GO:0030007)3.10351391
79eye photoreceptor cell development (GO:0042462)3.09382213
80establishment of mitochondrion localization (GO:0051654)3.09184982
81regulation of long-term neuronal synaptic plasticity (GO:0048169)3.09151665
82mitochondrion transport along microtubule (GO:0047497)3.06118155
83establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.06118155
84dendrite morphogenesis (GO:0048813)3.05606476
85synaptic vesicle endocytosis (GO:0048488)3.04384066
86urinary tract smooth muscle contraction (GO:0014848)3.03471801
87axon cargo transport (GO:0008088)3.02723616
88positive regulation of synapse assembly (GO:0051965)3.00049236
89proline transport (GO:0015824)2.99490373
90dopamine receptor signaling pathway (GO:0007212)2.98985908
91spinal cord development (GO:0021510)2.98260599
92transmission of nerve impulse (GO:0019226)2.98189003
93central nervous system neuron axonogenesis (GO:0021955)2.97493929
94behavioral response to nicotine (GO:0035095)2.97306555
95regulation of vesicle fusion (GO:0031338)2.96729486
96GMP metabolic process (GO:0046037)2.91603664
97positive regulation of CREB transcription factor activity (GO:0032793)2.90247703
98social behavior (GO:0035176)2.90190644
99intraspecies interaction between organisms (GO:0051703)2.90190644
100membrane depolarization (GO:0051899)2.89367516
101learning (GO:0007612)2.88240939
102dendritic spine organization (GO:0097061)2.87411546
103regulation of NFAT protein import into nucleus (GO:0051532)2.86413864
104establishment of synaptic vesicle localization (GO:0097480)2.86406377
105synaptic vesicle transport (GO:0048489)2.86406377
106sodium ion export (GO:0071436)2.86345465
107neuromuscular synaptic transmission (GO:0007274)2.86168555
108negative regulation of neurotransmitter secretion (GO:0046929)2.85975381
109negative regulation of cytosolic calcium ion concentration (GO:0051481)2.85032514
110astrocyte differentiation (GO:0048708)2.76752756
111camera-type eye morphogenesis (GO:0048593)2.73029367
112axon ensheathment in central nervous system (GO:0032291)2.64296115
113central nervous system myelination (GO:0022010)2.64296115
114regulation of ARF protein signal transduction (GO:0032012)2.63725761
115cell differentiation in hindbrain (GO:0021533)2.56842700
116negative regulation of neurotransmitter transport (GO:0051589)2.47170500
117histone H3-K9 modification (GO:0061647)2.46751858
118negative regulation of axonogenesis (GO:0050771)2.46746504
119histone H3-K9 methylation (GO:0051567)2.45657354
120cilium or flagellum-dependent cell motility (GO:0001539)2.44982348
121startle response (GO:0001964)2.44397778
122regulation of axon extension involved in axon guidance (GO:0048841)2.43686070
123regulation of axon guidance (GO:1902667)2.43500598
124neuronal ion channel clustering (GO:0045161)2.40702698
125negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.39929174
126dermatan sulfate metabolic process (GO:0030205)2.38701143
127regulation of neurotransmitter transport (GO:0051588)2.36321380
128synapse organization (GO:0050808)2.35414587
129cerebellar granule cell differentiation (GO:0021707)2.35118777
130nucleus localization (GO:0051647)2.33454191
131mechanosensory behavior (GO:0007638)2.31661638
132gamma-aminobutyric acid transport (GO:0015812)2.31603509
133regulation of axonogenesis (GO:0050770)2.31459597
134stress granule assembly (GO:0034063)2.30132492
135peripheral nervous system neuron development (GO:0048935)2.29836140
136adult walking behavior (GO:0007628)2.28336738
137peripheral nervous system axon ensheathment (GO:0032292)2.28207905
138myelination in peripheral nervous system (GO:0022011)2.28207905
139histone deubiquitination (GO:0016578)2.27719507
140limb development (GO:0060173)2.27261286
141appendage development (GO:0048736)2.27261286
142membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.27074417

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.56626794
2GBX2_23144817_ChIP-Seq_PC3_Human3.54668973
3* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.27590511
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.04162806
5REST_21632747_ChIP-Seq_MESCs_Mouse3.01439453
6CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.00381019
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.99397196
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.85194513
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.75580843
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.67102160
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.67102160
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59977934
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.54662176
14* EZH2_27294783_Chip-Seq_ESCs_Mouse2.53748704
15* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.49117829
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.45135789
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.44957989
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36929341
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.30719886
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.30436271
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.27117951
22* RNF2_27304074_Chip-Seq_ESCs_Mouse2.24346574
23IGF1R_20145208_ChIP-Seq_DFB_Human2.12380562
24ZNF274_21170338_ChIP-Seq_K562_Hela2.03385409
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.98700550
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.91804892
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.90156085
28DROSHA_22980978_ChIP-Seq_HELA_Human1.89461260
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.87592353
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85964194
31KDM2B_26808549_Chip-Seq_SUP-B15_Human1.78956536
32TAF15_26573619_Chip-Seq_HEK293_Human1.78577525
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.77510313
34BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.72654141
35RNF2_27304074_Chip-Seq_NSC_Mouse1.71733973
36EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.67612813
37IKZF1_21737484_ChIP-ChIP_HCT116_Human1.66220850
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64993803
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.62978066
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.62565422
41MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.61973630
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.58903171
43ZFP281_27345836_Chip-Seq_ESCs_Mouse1.56926890
44AR_21572438_ChIP-Seq_LNCaP_Human1.53227315
45LXR_22292898_ChIP-Seq_THP-1_Human1.51998626
46STAT6_21828071_ChIP-Seq_BEAS2B_Human1.50398030
47CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.50357672
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50309613
49KDM2B_26808549_Chip-Seq_DND41_Human1.47075523
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46863261
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.46139703
52ERG_21242973_ChIP-ChIP_JURKAT_Human1.44760572
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.42537334
54VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36841024
55* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.35978440
56SMAD4_21799915_ChIP-Seq_A2780_Human1.32212456
57RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.32193241
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30807819
59KDM2B_26808549_Chip-Seq_JURKAT_Human1.30663845
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.29632465
61VDR_21846776_ChIP-Seq_THP-1_Human1.29165884
62* RING1B_27294783_Chip-Seq_NPCs_Mouse1.29062194
63P68_20966046_ChIP-Seq_HELA_Human1.27156031
64MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.26985500
65SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.25123772
66TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24584532
67P300_19829295_ChIP-Seq_ESCs_Human1.21877625
68CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19159882
69SMC4_20622854_ChIP-Seq_HELA_Human1.18657667
70TP63_19390658_ChIP-ChIP_HaCaT_Human1.18144692
71KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.17042370
72* CREB1_26743006_Chip-Seq_LNCaP_Human1.16788141
73* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14289187
74VDR_22108803_ChIP-Seq_LS180_Human1.12617572
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12169633
76TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11087904
77P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10960537
78* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.10873065
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.10871700
80AR_25329375_ChIP-Seq_VCAP_Human1.10786109
81GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09493550
82MYC_22102868_ChIP-Seq_BL_Human1.06459319
83NR3C1_23031785_ChIP-Seq_PC12_Mouse1.06429291
84SMAD3_21741376_ChIP-Seq_EPCs_Human1.05612748
85TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.05610639
86RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05557035
87WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02538920
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.02121397
89KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00576137
90CTCF_27219007_Chip-Seq_Bcells_Human1.00242468
91SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00107906
92* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99704737
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99336989
94OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97253340
95OCT4_19829295_ChIP-Seq_ESCs_Human0.96770258
96DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.96586595
97TP53_23651856_ChIP-Seq_MEFs_Mouse0.96083873
98DNAJC2_21179169_ChIP-ChIP_NT2_Human0.96082521
99WDR5_24793694_ChIP-Seq_LNCAP_Human0.95972217
100TP53_22127205_ChIP-Seq_IMR90_Human0.94869348
101SOX2_21211035_ChIP-Seq_LN229_Gbm0.94848648
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94212511
103AR_19668381_ChIP-Seq_PC3_Human0.93322296
104GATA1_26923725_Chip-Seq_HPCs_Mouse0.93181708
105CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93101333
106TCF7_22412390_ChIP-Seq_EML_Mouse0.92612574
107NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92288576
108CTCF_27219007_Chip-Seq_ERYTHROID_Human0.92194401
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92064272
110ELK4_26923725_Chip-Seq_MESODERM_Mouse0.91554292
111TP53_20018659_ChIP-ChIP_R1E_Mouse0.91370350
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90963235
113YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90186846
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89122021
115PRDM14_20953172_ChIP-Seq_ESCs_Human0.89001830
116SA1_27219007_Chip-Seq_ERYTHROID_Human0.88928476
117RUNX2_22187159_ChIP-Seq_PCA_Human0.88796180
118KLF4_19829295_ChIP-Seq_ESCs_Human0.88298048
119PKCTHETA_26484144_Chip-Seq_BREAST_Human0.86713349
120ISL1_27105846_Chip-Seq_CPCs_Mouse0.86636122
121SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85733964
122STAT3_23295773_ChIP-Seq_U87_Human0.85546426
123ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.85452626
124PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85380081
125SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84081066
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.83823959
127MAF_26560356_Chip-Seq_TH2_Human0.83618454
128PIAS1_25552417_ChIP-Seq_VCAP_Human0.81597010
129SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81376132
130CDX2_19796622_ChIP-Seq_MESCs_Mouse0.80190060
131ER_23166858_ChIP-Seq_MCF-7_Human0.80035864
132POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.79714362
133TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79714362
134JUN_21703547_ChIP-Seq_K562_Human0.79479746
135KDM2B_26808549_Chip-Seq_K562_Human0.78722643
136TET1_21490601_ChIP-Seq_MESCs_Mouse0.77911940
137CBP_20019798_ChIP-Seq_JUKART_Human0.76913306
138IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.76913306
139FUS_26573619_Chip-Seq_HEK293_Human0.76269849
140KDM2B_26808549_Chip-Seq_REH_Human0.76190761
141TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.75958803
142GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.75861631
143NANOG_18555785_Chip-Seq_ESCs_Mouse0.75432567
144UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.74447431
145ZFP281_18757296_ChIP-ChIP_E14_Mouse0.73980094
146MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.73540348
147POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.72351217

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.43253915
2MP0003880_abnormal_central_pattern4.19119527
3MP0004270_analgesia3.57684409
4MP0005423_abnormal_somatic_nervous3.40056273
5MP0003635_abnormal_synaptic_transmissio3.30899548
6MP0001968_abnormal_touch/_nociception2.97507912
7MP0006276_abnormal_autonomic_nervous2.90338076
8MP0005171_absent_coat_pigmentation2.85091291
9MP0005551_abnormal_eye_electrophysiolog2.81636854
10MP0002734_abnormal_mechanical_nocicepti2.79064729
11MP0002735_abnormal_chemical_nociception2.71158262
12MP0002063_abnormal_learning/memory/cond2.62318170
13MP0009745_abnormal_behavioral_response2.55523916
14MP0003136_yellow_coat_color2.43266166
15MP0003283_abnormal_digestive_organ2.40436400
16MP0002064_seizures2.39364462
17MP0009046_muscle_twitch2.38691445
18MP0002272_abnormal_nervous_system2.37837384
19MP0002638_abnormal_pupillary_reflex2.33943264
20MP0001188_hyperpigmentation2.32758642
21MP0002184_abnormal_innervation2.32073278
22MP0002572_abnormal_emotion/affect_behav2.31793261
23MP0001486_abnormal_startle_reflex2.29712793
24MP0002733_abnormal_thermal_nociception2.22653994
25MP0006072_abnormal_retinal_apoptosis2.21392455
26MP0000778_abnormal_nervous_system2.17257290
27MP0002736_abnormal_nociception_after2.11751770
28MP0001970_abnormal_pain_threshold2.06356448
29MP0001984_abnormal_olfaction1.99800029
30MP0002067_abnormal_sensory_capabilities1.99377651
31MP0009379_abnormal_foot_pigmentation1.93316091
32MP0005253_abnormal_eye_physiology1.87744784
33MP0004858_abnormal_nervous_system1.85756325
34MP0002249_abnormal_larynx_morphology1.84653116
35MP0001986_abnormal_taste_sensitivity1.82529854
36MP0002557_abnormal_social/conspecific_i1.79738631
37MP0001440_abnormal_grooming_behavior1.77904896
38MP0001529_abnormal_vocalization1.76617349
39MP0003787_abnormal_imprinting1.73763888
40MP0003011_delayed_dark_adaptation1.68753771
41MP0002882_abnormal_neuron_morphology1.67845839
42MP0004811_abnormal_neuron_physiology1.64362065
43MP0000955_abnormal_spinal_cord1.63083252
44MP0001501_abnormal_sleep_pattern1.58567017
45MP0008569_lethality_at_weaning1.58044520
46MP0005409_darkened_coat_color1.57522295
47MP0001502_abnormal_circadian_rhythm1.55648269
48MP0001905_abnormal_dopamine_level1.54684354
49MP0003329_amyloid_beta_deposits1.52183340
50MP0004924_abnormal_behavior1.51534945
51MP0005386_behavior/neurological_phenoty1.51534945
52MP0004142_abnormal_muscle_tone1.51142280
53MP0010386_abnormal_urinary_bladder1.50720750
54MP0005645_abnormal_hypothalamus_physiol1.46708226
55MP0002928_abnormal_bile_duct1.43634246
56MP0008961_abnormal_basal_metabolism1.43333225
57MP0002752_abnormal_somatic_nervous1.42831273
58MP0003879_abnormal_hair_cell1.42251123
59MP0002229_neurodegeneration1.40213343
60MP0000631_abnormal_neuroendocrine_gland1.38868758
61MP0006292_abnormal_olfactory_placode1.38014343
62MP0002909_abnormal_adrenal_gland1.33824188
63MP0004130_abnormal_muscle_cell1.31985421
64MP0005394_taste/olfaction_phenotype1.31453745
65MP0005499_abnormal_olfactory_system1.31453745
66MP0002066_abnormal_motor_capabilities/c1.25164351
67MP0004133_heterotaxia1.24627893
68MP0005646_abnormal_pituitary_gland1.20040602
69MP0004145_abnormal_muscle_electrophysio1.19495916
70MP0000538_abnormal_urinary_bladder1.18257835
71MP0005195_abnormal_posterior_eye1.18232779
72MP0002751_abnormal_autonomic_nervous1.18160449
73MP0003942_abnormal_urinary_system1.15937099
74MP0004885_abnormal_endolymph1.14111567
75MP0002152_abnormal_brain_morphology1.13907422
76MP0008789_abnormal_olfactory_epithelium1.12861697
77MP0002009_preneoplasia1.12225430
78MP0000537_abnormal_urethra_morphology1.09119960
79MP0002653_abnormal_ependyma_morphology1.06424857
80MP0004742_abnormal_vestibular_system1.04396431
81MP0005174_abnormal_tail_pigmentation1.04395285
82MP0000534_abnormal_ureter_morphology1.03590689
83MP0002822_catalepsy1.02397874
84MP0000015_abnormal_ear_pigmentation1.00450802
85MP0001963_abnormal_hearing_physiology0.97840781
86MP0001270_distended_abdomen0.96984293
87MP0002102_abnormal_ear_morphology0.96495242
88MP0000566_synostosis0.96149670
89MP0002876_abnormal_thyroid_physiology0.93578779
90MP0003121_genomic_imprinting0.92791506
91MP0002090_abnormal_vision0.90010421
92MP0000569_abnormal_digit_pigmentation0.88420357
93MP0001944_abnormal_pancreas_morphology0.86810823
94MP0009278_abnormal_bone_marrow0.85771758
95MP0003122_maternal_imprinting0.85388734
96MP0003634_abnormal_glial_cell0.85345291
97MP0001348_abnormal_lacrimal_gland0.82704255
98MP0010770_preweaning_lethality0.82652222
99MP0002082_postnatal_lethality0.82652222
100MP0000026_abnormal_inner_ear0.82377944
101MP0002089_abnormal_postnatal_growth/wei0.82112018
102MP0002116_abnormal_craniofacial_bone0.80964804
103MP0001756_abnormal_urination0.80921827
104MP0010769_abnormal_survival0.80702166
105MP0003119_abnormal_digestive_system0.80531874
106MP0003633_abnormal_nervous_system0.79114037
107MP0001958_emphysema0.78645664
108MP0003861_abnormal_nervous_system0.78277677
109MP0002069_abnormal_eating/drinking_beha0.77938468
110MP0005220_abnormal_exocrine_pancreas0.77783489
111MP0010768_mortality/aging0.76900309
112MP0005187_abnormal_penis_morphology0.76214738
113MP0000751_myopathy0.75773391
114MP0001943_abnormal_respiration0.73939853
115MP0003631_nervous_system_phenotype0.71108404
116MP0003137_abnormal_impulse_conducting0.70705293
117MP0001324_abnormal_eye_pigmentation0.70314331
118MP0005391_vision/eye_phenotype0.70311806
119MP0000681_abnormal_thyroid_gland0.65607203
120MP0003646_muscle_fatigue0.65492841
121MP0009780_abnormal_chondrocyte_physiolo0.64086917
122MP0004085_abnormal_heartbeat0.63936464
123MP0001664_abnormal_digestion0.60600145
124MP0008872_abnormal_physiological_respon0.58955848
125MP0005535_abnormal_body_temperature0.57706474
126MP0003938_abnormal_ear_development0.57703864
127MP0004215_abnormal_myocardial_fiber0.55840281
128MP0000372_irregular_coat_pigmentation0.55346008
129MP0008995_early_reproductive_senescence0.54353797
130MP0003183_abnormal_peptide_metabolism0.53846491

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)6.27725087
2Myokymia (HP:0002411)5.30129765
3Focal motor seizures (HP:0011153)5.28340447
4Absent rod-and cone-mediated responses on ERG (HP:0007688)5.04313984
5Abnormal rod and cone electroretinograms (HP:0008323)4.81633283
6Bony spicule pigmentary retinopathy (HP:0007737)4.66480647
7Visual hallucinations (HP:0002367)4.22797891
8Focal seizures (HP:0007359)4.17282124
9Epileptic encephalopathy (HP:0200134)3.98721420
10Febrile seizures (HP:0002373)3.91105057
11Severe visual impairment (HP:0001141)3.83642416
12Turricephaly (HP:0000262)3.75651256
13Obstructive sleep apnea (HP:0002870)3.65382274
14Progressive cerebellar ataxia (HP:0002073)3.58280612
15Abnormality of macular pigmentation (HP:0008002)3.57968286
16Attenuation of retinal blood vessels (HP:0007843)3.57909413
17Decreased central vision (HP:0007663)3.47194343
18Central scotoma (HP:0000603)3.45077117
19Mutism (HP:0002300)3.34910209
20Hypothermia (HP:0002045)3.33738690
21Atonic seizures (HP:0010819)3.31899492
22Absence seizures (HP:0002121)3.22465334
23Action tremor (HP:0002345)3.12118538
24Limb dystonia (HP:0002451)3.10416228
25Ankle clonus (HP:0011448)3.06708159
26Pendular nystagmus (HP:0012043)3.05385730
27Supranuclear gaze palsy (HP:0000605)3.00796807
28Ulnar bowing (HP:0003031)2.97806983
29Dialeptic seizures (HP:0011146)2.94476615
30Broad-based gait (HP:0002136)2.94096478
31Gait imbalance (HP:0002141)2.90541357
32Annular pancreas (HP:0001734)2.87478676
33Progressive inability to walk (HP:0002505)2.84003213
34Abnormality of the aortic arch (HP:0012303)2.75712336
35Truncal ataxia (HP:0002078)2.74839959
36Rib fusion (HP:0000902)2.73060248
37Tented upper lip vermilion (HP:0010804)2.71681307
38Dyschromatopsia (HP:0007641)2.69976730
39Scotoma (HP:0000575)2.64207426
40Hemiparesis (HP:0001269)2.63709233
41Generalized tonic-clonic seizures (HP:0002069)2.59982719
42Agitation (HP:0000713)2.58628469
43Shawl scrotum (HP:0000049)2.57594903
44Polyphagia (HP:0002591)2.57444916
45Abnormality of the fingertips (HP:0001211)2.55254653
46Short 4th metacarpal (HP:0010044)2.49425726
47Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.49425726
48Increased corneal curvature (HP:0100692)2.48728680
49Keratoconus (HP:0000563)2.48728680
50Amblyopia (HP:0000646)2.48525724
51Gaze-evoked nystagmus (HP:0000640)2.47856459
52Protruding tongue (HP:0010808)2.44807615
53Depression (HP:0000716)2.43655400
54Chronic hepatic failure (HP:0100626)2.40179826
55Abnormality of the 4th metacarpal (HP:0010012)2.39829679
56Medial flaring of the eyebrow (HP:0010747)2.38988504
57Intestinal fistula (HP:0100819)2.38612509
58Anxiety (HP:0000739)2.38466007
59Abnormal eating behavior (HP:0100738)2.38179538
60Exotropia (HP:0000577)2.35163015
61Inability to walk (HP:0002540)2.34338197
62Papilledema (HP:0001085)2.31902788
63Drooling (HP:0002307)2.31207623
64Excessive salivation (HP:0003781)2.31207623
65Facial hemangioma (HP:0000329)2.31091062
66Narrow nasal bridge (HP:0000446)2.30871468
67Sleep apnea (HP:0010535)2.30670557
68Aplasia/Hypoplasia of the brainstem (HP:0007362)2.29496336
69Hypoplasia of the brainstem (HP:0002365)2.29496336
70Congenital primary aphakia (HP:0007707)2.28528283
71Type II diabetes mellitus (HP:0005978)2.26207923
72Poor eye contact (HP:0000817)2.23456942
73Photophobia (HP:0000613)2.21397267
74Testicular atrophy (HP:0000029)2.20611191
75Optic nerve coloboma (HP:0000588)2.19465084
76Amyotrophic lateral sclerosis (HP:0007354)2.18118176
77Poor suck (HP:0002033)2.15955311
78Neonatal hypoglycemia (HP:0001998)2.12653283
79Retinitis pigmentosa (HP:0000510)2.12079287
80Specific learning disability (HP:0001328)2.10819201
81Nephrogenic diabetes insipidus (HP:0009806)2.10575374
82Lissencephaly (HP:0001339)2.08928411
83Choroideremia (HP:0001139)2.08796723
84Esotropia (HP:0000565)2.08076488
85Hemiplegia (HP:0002301)2.07390136
86Broad face (HP:0000283)2.06788726
87True hermaphroditism (HP:0010459)2.06631003
88Morphological abnormality of the middle ear (HP:0008609)2.06136200
89EEG with generalized epileptiform discharges (HP:0011198)2.05383866
90Patellar aplasia (HP:0006443)2.04652861
91Epileptiform EEG discharges (HP:0011182)2.04572735
92Ulnar claw (HP:0001178)2.04142135
93Spastic gait (HP:0002064)2.03786035
94Abnormality of the corticospinal tract (HP:0002492)2.02100777
95Pancreatic fibrosis (HP:0100732)2.01944849
96Urinary bladder sphincter dysfunction (HP:0002839)2.01158501
97Truncal obesity (HP:0001956)2.00282925
98Obsessive-compulsive behavior (HP:0000722)2.00133211
99Delusions (HP:0000746)1.99436964
100Dysdiadochokinesis (HP:0002075)1.98292275
101Fetal akinesia sequence (HP:0001989)1.97672765
102Genetic anticipation (HP:0003743)1.96967008
103Optic disc pallor (HP:0000543)1.96640358
104Neoplasm of the heart (HP:0100544)1.95022330
105Abolished electroretinogram (ERG) (HP:0000550)1.94909002
106Abnormality of binocular vision (HP:0011514)1.94833045
107Diplopia (HP:0000651)1.94833045
108Horizontal nystagmus (HP:0000666)1.94535361
109Pheochromocytoma (HP:0002666)1.93758612
110Absent speech (HP:0001344)1.93732329
111Abnormal social behavior (HP:0012433)1.93291478
112Impaired social interactions (HP:0000735)1.93291478
113Dysmetric saccades (HP:0000641)1.92270495
114Narrow palate (HP:0000189)1.90992738
115Stereotypic behavior (HP:0000733)1.90244619
116Akinesia (HP:0002304)1.89498020
117Bradykinesia (HP:0002067)1.89265077
118Scanning speech (HP:0002168)1.88524832
119Poikiloderma (HP:0001029)1.88214211
120Rectovaginal fistula (HP:0000143)1.88139236
121Rectal fistula (HP:0100590)1.88139236
122Myotonia (HP:0002486)1.87784609
123Hypsarrhythmia (HP:0002521)1.85918864
124Round face (HP:0000311)1.84392066
125Heterotopia (HP:0002282)1.84223864
126Urinary urgency (HP:0000012)1.84212268
127Laryngomalacia (HP:0001601)1.82619018
128Aplasia/Hypoplasia of the patella (HP:0006498)1.82184513
129Retinal dysplasia (HP:0007973)1.81906503
130Submucous cleft hard palate (HP:0000176)1.81734254
131Thin ribs (HP:0000883)1.81626027
132Constricted visual fields (HP:0001133)1.81073014
133Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.80033703
134Impaired vibration sensation in the lower limbs (HP:0002166)1.79810970
135Germ cell neoplasia (HP:0100728)1.79749533
136Dysmetria (HP:0001310)1.78635708
137Nephronophthisis (HP:0000090)1.78148298
138Overgrowth (HP:0001548)1.77933270
139Abnormality of the phalanges of the hallux (HP:0010057)1.77638672
140Genital tract atresia (HP:0001827)1.77304515
141Torticollis (HP:0000473)1.77180182
142Cortical visual impairment (HP:0100704)1.77041966
143Bronchomalacia (HP:0002780)1.76976033
144Neuroendocrine neoplasm (HP:0100634)1.76558513
145Abnormality of the ischium (HP:0003174)1.76244230
146Impaired smooth pursuit (HP:0007772)1.75972390
147Hypoventilation (HP:0002791)1.74854448
148Vaginal atresia (HP:0000148)1.73867961
149Hyperventilation (HP:0002883)1.72835762
150Prolonged QT interval (HP:0001657)1.72618783
151Tracheomalacia (HP:0002779)1.72493999
152Restlessness (HP:0000711)1.71462714
153Intellectual disability, severe (HP:0010864)1.70927847
154Long eyelashes (HP:0000527)1.69528159
155Macroorchidism (HP:0000053)1.69152864
156Hepatoblastoma (HP:0002884)1.67703967
157Coronal craniosynostosis (HP:0004440)1.67501114
158Trigonocephaly (HP:0000243)1.66932296
159Mesangial abnormality (HP:0001966)1.65999305
160Failure to thrive in infancy (HP:0001531)1.65023899
161Wide anterior fontanel (HP:0000260)1.64667430
162Spina bifida occulta (HP:0003298)1.64376552
163Hypoplastic nipples (HP:0002557)1.63486151
164Abnormality of the intervertebral disk (HP:0005108)1.62793304
165Abnormality of ocular smooth pursuit (HP:0000617)1.62220344
166Mask-like facies (HP:0000298)1.60977418
167Deep palmar crease (HP:0006191)1.60306610
168Vaginal fistula (HP:0004320)1.60065954

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.34080134
2TNIK3.50128963
3NTRK33.43248076
4MAPK153.27635736
5MAP2K73.14386389
6MAP3K93.04147362
7MINK12.75291919
8CASK2.64814073
9MUSK2.62201719
10NTRK22.44403468
11MAP3K42.42802252
12PRKD32.36665695
13FRK2.31094776
14MAP3K122.29719501
15MAPK132.25973000
16CAMK1D2.08440596
17TNK22.07594564
18TRIB32.00929077
19PAK61.98875977
20EPHA41.98214715
21DYRK21.95244506
22PNCK1.86312443
23CAMKK21.86282751
24CAMKK11.78279873
25SIK21.76790803
26CDK191.68974277
27AKT31.67867178
28PHKG11.65991088
29PHKG21.65991088
30CDK121.53481092
31UHMK11.49546698
32PRKCH1.49525861
33PRKD21.45969598
34MAP3K71.41664982
35KSR11.40094438
36FGFR21.37752887
37ICK1.37124353
38MAP2K41.35168530
39CDK51.34052885
40EPHB21.32881771
41GRK51.32754103
42NTRK11.31636121
43SIK11.30725204
44STK161.29116698
45DAPK21.22616342
46EEF2K1.18781161
47IRAK21.17481092
48CSNK1G21.13642240
49BRD41.08627011
50CAMK11.08456080
51DYRK1A1.07806325
52ERBB31.07367203
53PRKCG1.05350471
54INSRR1.04984781
55PINK11.02841476
56DAPK11.01593241
57KSR20.97255612
58MTOR0.94879165
59CSNK1G30.94775594
60CCNB10.94502267
61SIK30.87554993
62BLK0.87246609
63PRPF4B0.86773866
64GRK10.86248596
65PRKAA10.85611823
66STK380.83220468
67CDK180.83192683
68CDK140.81116264
69FES0.80192337
70DYRK1B0.80110791
71CAMK2A0.79619029
72ARAF0.79323006
73CDK150.78390004
74SGK30.77791187
75WNK40.74498166
76CDK11A0.73177104
77WNK10.71731932
78PKN10.71328752
79MARK20.70653713
80WNK30.68920092
81LIMK10.67850071
82PRKCZ0.67390605
83SMG10.66570264
84SGK4940.65616791
85SGK2230.65616791
86RIPK40.64874116
87MAP4K10.63963402
88RPS6KA20.63363066
89PAK30.62713186
90ADRBK10.62377635
91PLK20.61835480
92BMPR1B0.61557177
93CAMK2B0.61370901
94MAP3K100.60910475
95STK110.59683701
96CSNK1G10.58485567
97PDGFRB0.57752539
98TAOK30.56653225
99ADRBK20.54758423
100LATS20.54499929
101MAPK90.51846885
102RPS6KA60.51487603
103CSNK1A1L0.50467063
104CDC42BPA0.49943170
105MATK0.49183557
106RPS6KL10.48744975
107RPS6KC10.48744975
108BCR0.47788076
109MAPK70.46798402
110MAPK80.46621574
111RAF10.46032011
112RET0.45545013
113PRKCE0.45314012
114PRKD10.44934626
115PASK0.44480197
116SGK10.42794968
117PDGFRA0.40143788
118FGFR30.39457737
119GSK3B0.39447470
120MAPK40.39384857
121CAMK40.38610974
122LMTK20.38466824
123CAMK2D0.38140230
124TAOK10.37357255
125HIPK20.37136303
126MAPK110.36605033
127MAPK120.36150746
128NME10.36005057
129SCYL20.35642831
130MELK0.35315282
131PRKACA0.34861386
132MAPKAPK50.34611083
133ERBB20.34591073
134CAMK1G0.33495451
135SGK20.32306952
136NEK60.32069651
137MAPK100.32065053
138RPS6KA30.31382701
139TYRO30.31161845
140GRK70.31041699
141CDK30.30648594
142EPHA30.30402350
143RPS6KB10.29877349
144PRKCI0.29395776

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047445.08271278
2Nicotine addiction_Homo sapiens_hsa050333.89933107
3Synaptic vesicle cycle_Homo sapiens_hsa047213.53163743
4GABAergic synapse_Homo sapiens_hsa047272.64625762
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.60546381
6Olfactory transduction_Homo sapiens_hsa047402.58645218
7Circadian entrainment_Homo sapiens_hsa047132.53566041
8Glutamatergic synapse_Homo sapiens_hsa047242.46510248
9Morphine addiction_Homo sapiens_hsa050322.35439444
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.25251704
11Dopaminergic synapse_Homo sapiens_hsa047282.15637122
12Cholinergic synapse_Homo sapiens_hsa047252.05673830
13Serotonergic synapse_Homo sapiens_hsa047262.00289135
14Insulin secretion_Homo sapiens_hsa049111.96491214
15Long-term potentiation_Homo sapiens_hsa047201.92393693
16Amphetamine addiction_Homo sapiens_hsa050311.89165603
17Taste transduction_Homo sapiens_hsa047421.88692462
18Salivary secretion_Homo sapiens_hsa049701.77949273
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.60875375
20Notch signaling pathway_Homo sapiens_hsa043301.58604482
21Long-term depression_Homo sapiens_hsa047301.57952947
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.56383903
23Cocaine addiction_Homo sapiens_hsa050301.54495133
24Lysine degradation_Homo sapiens_hsa003101.49515721
25Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.47266162
26Basal cell carcinoma_Homo sapiens_hsa052171.44733007
27Oxytocin signaling pathway_Homo sapiens_hsa049211.42899151
28Gap junction_Homo sapiens_hsa045401.41969964
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.36470260
30Axon guidance_Homo sapiens_hsa043601.33875965
31Renin secretion_Homo sapiens_hsa049241.33817267
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.32951269
33Calcium signaling pathway_Homo sapiens_hsa040201.32184251
34Cardiac muscle contraction_Homo sapiens_hsa042601.30616590
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.30448883
36Gastric acid secretion_Homo sapiens_hsa049711.26125388
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19957280
38Collecting duct acid secretion_Homo sapiens_hsa049661.18819642
39Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.14709613
40GnRH signaling pathway_Homo sapiens_hsa049121.13667010
41Oxidative phosphorylation_Homo sapiens_hsa001901.07998031
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05142041
43Vibrio cholerae infection_Homo sapiens_hsa051101.02353419
44Parkinsons disease_Homo sapiens_hsa050120.98918453
45Circadian rhythm_Homo sapiens_hsa047100.98360178
46cAMP signaling pathway_Homo sapiens_hsa040240.96141855
47Ovarian steroidogenesis_Homo sapiens_hsa049130.95062674
48Alzheimers disease_Homo sapiens_hsa050100.95052773
49Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94893115
50Melanogenesis_Homo sapiens_hsa049160.94023779
51Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.93059344
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.92485891
53Alcoholism_Homo sapiens_hsa050340.90994483
54Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88688278
55N-Glycan biosynthesis_Homo sapiens_hsa005100.87376189
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.83223164
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.82849836
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81262734
59FoxO signaling pathway_Homo sapiens_hsa040680.79673790
60ErbB signaling pathway_Homo sapiens_hsa040120.79643698
61Prolactin signaling pathway_Homo sapiens_hsa049170.78046953
62Oocyte meiosis_Homo sapiens_hsa041140.77964531
63Bile secretion_Homo sapiens_hsa049760.75531416
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74729917
65Huntingtons disease_Homo sapiens_hsa050160.74341006
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74130930
67Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73942548
68Non-small cell lung cancer_Homo sapiens_hsa052230.73917564
69Estrogen signaling pathway_Homo sapiens_hsa049150.71383806
70Type II diabetes mellitus_Homo sapiens_hsa049300.70892384
71Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70800425
72Hippo signaling pathway_Homo sapiens_hsa043900.70050466
73Regulation of autophagy_Homo sapiens_hsa041400.68939321
74Pancreatic secretion_Homo sapiens_hsa049720.68779620
75Rap1 signaling pathway_Homo sapiens_hsa040150.66643159
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66573079
77AMPK signaling pathway_Homo sapiens_hsa041520.66391943
78ABC transporters_Homo sapiens_hsa020100.65016283
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.64832817
80Vascular smooth muscle contraction_Homo sapiens_hsa042700.62801612
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.62072853
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.60291149
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.60110826
84Chronic myeloid leukemia_Homo sapiens_hsa052200.59542943
85Wnt signaling pathway_Homo sapiens_hsa043100.58444831
86Glycerolipid metabolism_Homo sapiens_hsa005610.57297129
87Glioma_Homo sapiens_hsa052140.57069566
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56328768
89T cell receptor signaling pathway_Homo sapiens_hsa046600.53267254
90Prostate cancer_Homo sapiens_hsa052150.53175238
91Colorectal cancer_Homo sapiens_hsa052100.51443086
92Platelet activation_Homo sapiens_hsa046110.51223593
93Glucagon signaling pathway_Homo sapiens_hsa049220.51166291
94Choline metabolism in cancer_Homo sapiens_hsa052310.51129282
95MicroRNAs in cancer_Homo sapiens_hsa052060.51118163
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.48981595
97Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.47470089
98Cyanoamino acid metabolism_Homo sapiens_hsa004600.47122531
99Sulfur relay system_Homo sapiens_hsa041220.47108507
100Ras signaling pathway_Homo sapiens_hsa040140.46817196
101MAPK signaling pathway_Homo sapiens_hsa040100.45930961
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45444396
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44581081
104Thyroid hormone synthesis_Homo sapiens_hsa049180.42901787
105Inositol phosphate metabolism_Homo sapiens_hsa005620.42500725
106Endocytosis_Homo sapiens_hsa041440.41151554
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.39244933
108VEGF signaling pathway_Homo sapiens_hsa043700.39026699
109Endometrial cancer_Homo sapiens_hsa052130.38873609
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38770223
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37686166
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35731059
113Purine metabolism_Homo sapiens_hsa002300.31198373
114Insulin signaling pathway_Homo sapiens_hsa049100.29454785
115Hedgehog signaling pathway_Homo sapiens_hsa043400.28608964
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.28123550
117Renal cell carcinoma_Homo sapiens_hsa052110.28029760
118Dilated cardiomyopathy_Homo sapiens_hsa054140.27216296
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27023920
120Type I diabetes mellitus_Homo sapiens_hsa049400.26060085
121mTOR signaling pathway_Homo sapiens_hsa041500.25894893
122Sphingolipid metabolism_Homo sapiens_hsa006000.25473024
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24872827
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.24755473
125Dorso-ventral axis formation_Homo sapiens_hsa043200.23888434

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