SARNP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.65300585
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.37033424
3ribosomal small subunit biogenesis (GO:0042274)5.16113428
4ATP synthesis coupled proton transport (GO:0015986)5.03828176
5energy coupled proton transport, down electrochemical gradient (GO:0015985)5.03828176
6viral transcription (GO:0019083)4.95198992
7translational termination (GO:0006415)4.84829348
8maturation of SSU-rRNA (GO:0030490)4.84692631
9proteasome assembly (GO:0043248)4.61262345
10cotranslational protein targeting to membrane (GO:0006613)4.44812343
11SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.44515540
12protein targeting to ER (GO:0045047)4.36587656
13cullin deneddylation (GO:0010388)4.29359933
14negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.27918651
15ribosomal large subunit biogenesis (GO:0042273)4.22107229
16translational elongation (GO:0006414)4.19635615
17protein localization to endoplasmic reticulum (GO:0070972)4.16099975
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.12803753
19telomere maintenance via semi-conservative replication (GO:0032201)3.99681546
20CENP-A containing nucleosome assembly (GO:0034080)3.99236885
21protein deneddylation (GO:0000338)3.97676865
22positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.95878655
23establishment of integrated proviral latency (GO:0075713)3.93333459
24negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.92824879
25negative regulation of ligase activity (GO:0051352)3.92824879
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.92528353
27establishment of protein localization to mitochondrial membrane (GO:0090151)3.92045171
28transcription elongation from RNA polymerase III promoter (GO:0006385)3.91551251
29termination of RNA polymerase III transcription (GO:0006386)3.91551251
30translational initiation (GO:0006413)3.90907500
31protein neddylation (GO:0045116)3.88594003
32DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.87976584
33cellular protein complex disassembly (GO:0043624)3.87789502
34chromatin remodeling at centromere (GO:0031055)3.85978710
35viral life cycle (GO:0019058)3.84286619
36nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.83312620
37anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.82697259
38mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.82503152
39signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.81901961
40intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.81901961
41RNA capping (GO:0036260)3.79518930
427-methylguanosine RNA capping (GO:0009452)3.79518930
43signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.78987633
44signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.78987633
45signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.78987633
46DNA strand elongation involved in DNA replication (GO:0006271)3.76345257
47translation (GO:0006412)3.74992333
487-methylguanosine mRNA capping (GO:0006370)3.74756061
49ribonucleoprotein complex biogenesis (GO:0022613)3.73915810
50formation of translation preinitiation complex (GO:0001731)3.73673605
51regulation of cellular amino acid metabolic process (GO:0006521)3.72258593
52respiratory chain complex IV assembly (GO:0008535)3.71950779
53DNA damage response, detection of DNA damage (GO:0042769)3.70724499
54telomere maintenance via recombination (GO:0000722)3.70279838
55signal transduction involved in DNA integrity checkpoint (GO:0072401)3.69946177
56signal transduction involved in DNA damage checkpoint (GO:0072422)3.69946177
57histone exchange (GO:0043486)3.67681138
58signal transduction involved in cell cycle checkpoint (GO:0072395)3.66625678
59antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.63656595
60DNA strand elongation (GO:0022616)3.58630999
61regulation of mitochondrial translation (GO:0070129)3.53350920
62spliceosomal snRNP assembly (GO:0000387)3.51271377
63respiratory electron transport chain (GO:0022904)3.51063277
64regulation of mitotic spindle checkpoint (GO:1903504)3.50682899
65regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.50682899
66transcription-coupled nucleotide-excision repair (GO:0006283)3.49761634
67mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49542734
68mitochondrial respiratory chain complex I assembly (GO:0032981)3.49542734
69NADH dehydrogenase complex assembly (GO:0010257)3.49542734
70nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.49341358
71rRNA processing (GO:0006364)3.49013817
72transcription elongation from RNA polymerase I promoter (GO:0006362)3.47613928
73exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.46978853
74kinetochore organization (GO:0051383)3.46403756
75DNA replication initiation (GO:0006270)3.45574202
76mitotic recombination (GO:0006312)3.45355939
77inner mitochondrial membrane organization (GO:0007007)3.43055687
78electron transport chain (GO:0022900)3.41966270
79spliceosomal complex assembly (GO:0000245)3.41394800
80establishment of viral latency (GO:0019043)3.39943031
81antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.39871270
82chaperone-mediated protein transport (GO:0072321)3.39206887
83GTP biosynthetic process (GO:0006183)3.37734303
84positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.36558221
85DNA deamination (GO:0045006)3.36485774
86nucleotide-excision repair, DNA gap filling (GO:0006297)3.36130708
87cellular component biogenesis (GO:0044085)3.35273268
88rRNA metabolic process (GO:0016072)3.34973365
89protein complex disassembly (GO:0043241)3.34623597
90cytochrome complex assembly (GO:0017004)3.34006235
91termination of RNA polymerase I transcription (GO:0006363)3.29259370
92protein complex biogenesis (GO:0070271)3.28605570
93protein targeting to mitochondrion (GO:0006626)3.27652258
94kinetochore assembly (GO:0051382)3.27134181
95rRNA modification (GO:0000154)3.26771517
96positive regulation of ligase activity (GO:0051351)3.24731685
97DNA replication-independent nucleosome assembly (GO:0006336)3.24242393
98DNA replication-independent nucleosome organization (GO:0034724)3.24242393
99deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.22996252
100macromolecular complex disassembly (GO:0032984)3.20455888
101DNA double-strand break processing (GO:0000729)3.20217575
102establishment of protein localization to mitochondrion (GO:0072655)3.19136880
103transcription from RNA polymerase I promoter (GO:0006360)3.16324474
104protein localization to mitochondrion (GO:0070585)3.16235005
105telomere maintenance via telomere lengthening (GO:0010833)3.15456568
106ATP biosynthetic process (GO:0006754)3.14593221
107DNA replication checkpoint (GO:0000076)3.12786287
108nuclear-transcribed mRNA catabolic process (GO:0000956)3.11842421
109oxidative phosphorylation (GO:0006119)3.11464804
110viral mRNA export from host cell nucleus (GO:0046784)3.10933892
111cell cycle G1/S phase transition (GO:0044843)3.10274379
112G1/S transition of mitotic cell cycle (GO:0000082)3.10274379
113DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.10233025
114sequestering of actin monomers (GO:0042989)3.09784809
115mitochondrial respiratory chain complex assembly (GO:0033108)3.08842679
116DNA ligation (GO:0006266)3.08619606
117regulation of helicase activity (GO:0051095)3.06492708
118mitotic metaphase plate congression (GO:0007080)3.05351641
119purine nucleoside triphosphate biosynthetic process (GO:0009145)2.99140500
120purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.97634880
121histone mRNA metabolic process (GO:0008334)2.97246679
122RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.95275244
123tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.95275244
124negative regulation of DNA-dependent DNA replication (GO:2000104)2.94879087
125hydrogen ion transmembrane transport (GO:1902600)2.91836985
126purine nucleobase biosynthetic process (GO:0009113)2.90890781
127intracellular protein transmembrane import (GO:0044743)2.89688807
128organelle disassembly (GO:1903008)2.87565740
129pseudouridine synthesis (GO:0001522)2.86946520

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.07021900
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.68519895
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.34199361
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.26087693
5GABP_17652178_ChIP-ChIP_JURKAT_Human4.24013197
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.80773612
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.57641071
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.39289537
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.32249445
10CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.30654625
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.29693274
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.28183191
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.26960442
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.94087762
15* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.91621051
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89469504
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87160322
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.86953498
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86208886
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.81039669
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.73317493
22* VDR_23849224_ChIP-Seq_CD4+_Human2.66331581
23* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.63328511
24ELK1_19687146_ChIP-ChIP_HELA_Human2.55027996
25* XRN2_22483619_ChIP-Seq_HELA_Human2.34078546
26DCP1A_22483619_ChIP-Seq_HELA_Human2.32786386
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31310894
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.26089103
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.22556554
30FOXM1_23109430_ChIP-Seq_U2OS_Human2.20344147
31FOXP3_21729870_ChIP-Seq_TREG_Human2.19900967
32THAP11_20581084_ChIP-Seq_MESCs_Mouse2.18539015
33SRF_21415370_ChIP-Seq_HL-1_Mouse2.16448730
34TTF2_22483619_ChIP-Seq_HELA_Human2.16377674
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.02829921
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.98328665
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.96409619
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.96406931
39ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.90129865
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.89512395
41* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.86167393
42ZNF274_21170338_ChIP-Seq_K562_Hela1.85128746
43GABP_19822575_ChIP-Seq_HepG2_Human1.83500834
44VDR_22108803_ChIP-Seq_LS180_Human1.81110704
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78284225
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.77482076
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.77376792
48SALL1_21062744_ChIP-ChIP_HESCs_Human1.76326074
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.74928062
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68718337
51MYCN_18555785_ChIP-Seq_MESCs_Mouse1.55769395
52PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52974058
53AR_21909140_ChIP-Seq_LNCAP_Human1.45046565
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.44046120
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.42043132
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.41737448
57IGF1R_20145208_ChIP-Seq_DFB_Human1.40852776
58ELK1_22589737_ChIP-Seq_MCF10A_Human1.40569852
59ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36013617
60ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.35065835
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34857559
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34506142
63TAF15_26573619_Chip-Seq_HEK293_Human1.33199411
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.30947753
65MYC_18940864_ChIP-ChIP_HL60_Human1.29938689
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.26800195
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.26052755
68IRF1_19129219_ChIP-ChIP_H3396_Human1.25736974
69P300_19829295_ChIP-Seq_ESCs_Human1.22584442
70* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.21829832
71CIITA_25753668_ChIP-Seq_RAJI_Human1.21373619
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.19488487
73ZFP57_27257070_Chip-Seq_ESCs_Mouse1.18926638
74ZFX_18555785_ChIP-Seq_MESCs_Mouse1.18421945
75CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17460163
76SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13925656
77KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.12966738
78CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.09793477
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08322276
80CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07628103
81SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.06034840
82TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.05981229
83BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04368502
84TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04196073
85KDM5A_27292631_Chip-Seq_BREAST_Human1.02722737
86NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02431087
87SOX17_20123909_ChIP-Seq_XEN_Mouse1.01932272
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.01065769
89CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00963610
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.99146519
91NOTCH1_21737748_ChIP-Seq_TLL_Human0.98094660
92HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.94369700
93POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94085515
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93177122
95GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92899425
96CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92845983
97FUS_26573619_Chip-Seq_HEK293_Human0.92681913
98EWS_26573619_Chip-Seq_HEK293_Human0.92423777
99IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.90833207
100DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89348640
101GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.85390844
102FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.84806673
103E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.84003187
104TP53_22573176_ChIP-Seq_HFKS_Human0.83441708
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.82509815
106CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80867984
107GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79926174
108* SPI1_23547873_ChIP-Seq_NB4_Human0.79763368
109EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.78829496
110SOX2_16153702_ChIP-ChIP_HESCs_Human0.78597515
111GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78304943
112HTT_18923047_ChIP-ChIP_STHdh_Human0.75350526
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.75079405
114TFEB_21752829_ChIP-Seq_HELA_Human0.74716252
115HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.74606153
116NANOG_19829295_ChIP-Seq_ESCs_Human0.74322484
117SOX2_19829295_ChIP-Seq_ESCs_Human0.74322484
118SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.72348250
119UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.71344945
120NANOG_16153702_ChIP-ChIP_HESCs_Human0.71318898
121FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70682419
122POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.68294820
123SOX2_18692474_ChIP-Seq_MEFs_Mouse0.65095626
124ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.64655183
125OCT4_18692474_ChIP-Seq_MEFs_Mouse0.62534011
126KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.58486982
127KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.58486982
128KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.58486982

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.54310464
2MP0008057_abnormal_DNA_replication3.90653725
3MP0004957_abnormal_blastocyst_morpholog3.86809229
4MP0010094_abnormal_chromosome_stability3.74348364
5MP0009379_abnormal_foot_pigmentation3.38374680
6MP0008058_abnormal_DNA_repair3.27528604
7MP0003077_abnormal_cell_cycle3.23800800
8MP0003111_abnormal_nucleus_morphology3.03261565
9MP0008932_abnormal_embryonic_tissue2.71265865
10MP0008007_abnormal_cellular_replicative2.43665696
11MP0003786_premature_aging2.40506960
12MP0003123_paternal_imprinting2.40057090
13MP0001529_abnormal_vocalization2.36344454
14MP0008877_abnormal_DNA_methylation2.30367628
15MP0006292_abnormal_olfactory_placode2.25408190
16MP0003136_yellow_coat_color1.98411027
17MP0005499_abnormal_olfactory_system1.81251000
18MP0005394_taste/olfaction_phenotype1.81251000
19MP0003121_genomic_imprinting1.80387172
20MP0003186_abnormal_redox_activity1.77784323
21MP0003718_maternal_effect1.74218990
22MP0009697_abnormal_copulation1.59993453
23MP0002938_white_spotting1.55632791
24MP0002736_abnormal_nociception_after1.53094323
25MP0003315_abnormal_perineum_morphology1.51853169
26MP0005084_abnormal_gallbladder_morpholo1.49448045
27MP0003011_delayed_dark_adaptation1.45784883
28MP0001905_abnormal_dopamine_level1.45729404
29MP0006036_abnormal_mitochondrial_physio1.40128951
30MP0002163_abnormal_gland_morphology1.39430690
31MP0003880_abnormal_central_pattern1.38524202
32MP0002234_abnormal_pharynx_morphology1.38410493
33MP0000631_abnormal_neuroendocrine_gland1.38277439
34MP0005253_abnormal_eye_physiology1.35968738
35MP0001730_embryonic_growth_arrest1.35517311
36MP0002233_abnormal_nose_morphology1.35215373
37MP0001984_abnormal_olfaction1.34891362
38MP0002396_abnormal_hematopoietic_system1.34721489
39MP0000350_abnormal_cell_proliferation1.32709478
40MP0005409_darkened_coat_color1.30957784
41MP0001986_abnormal_taste_sensitivity1.30948147
42MP0002638_abnormal_pupillary_reflex1.30245435
43MP0001188_hyperpigmentation1.28508447
44MP0002282_abnormal_trachea_morphology1.27642403
45MP0000566_synostosis1.22922727
46MP0009333_abnormal_splenocyte_physiolog1.20987850
47MP0005551_abnormal_eye_electrophysiolog1.20317354
48MP0006054_spinal_hemorrhage1.19574905
49MP0002837_dystrophic_cardiac_calcinosis1.18145450
50MP0003806_abnormal_nucleotide_metabolis1.15764361
51MP0002102_abnormal_ear_morphology1.14810919
52MP0003119_abnormal_digestive_system1.14198850
53MP0002210_abnormal_sex_determination1.13594506
54MP0002697_abnormal_eye_size1.13012636
55MP0004133_heterotaxia1.12534825
56MP0000372_irregular_coat_pigmentation1.12499020
57MP0002653_abnormal_ependyma_morphology1.12402012
58MP0002132_abnormal_respiratory_system1.12281035
59MP0000647_abnormal_sebaceous_gland1.12035189
60MP0006035_abnormal_mitochondrial_morpho1.10012305
61MP0004147_increased_porphyrin_level1.08409681
62MP0000313_abnormal_cell_death1.06954966
63MP0003567_abnormal_fetal_cardiomyocyte1.05555845
64MP0000778_abnormal_nervous_system1.05385474
65MP0005408_hypopigmentation1.04376255
66MP0005075_abnormal_melanosome_morpholog1.03422720
67MP0008789_abnormal_olfactory_epithelium1.03354899
68MP0001727_abnormal_embryo_implantation1.02000734
69MP0002751_abnormal_autonomic_nervous1.01871858
70MP0000490_abnormal_crypts_of1.00555497
71MP0005391_vision/eye_phenotype0.99454173
72MP0003122_maternal_imprinting0.98926803
73MP0003763_abnormal_thymus_physiology0.97075683
74MP0001697_abnormal_embryo_size0.96437146
75MP0002148_abnormal_hypersensitivity_rea0.95955299
76MP0003941_abnormal_skin_development0.94433890
77MP0003890_abnormal_embryonic-extraembry0.92149913
78MP0001145_abnormal_male_reproductive0.91497751
79MP0003755_abnormal_palate_morphology0.90984933
80MP0003950_abnormal_plasma_membrane0.90767335
81MP0002160_abnormal_reproductive_system0.90659854
82MP0001968_abnormal_touch/_nociception0.89059749
83MP0000049_abnormal_middle_ear0.88651266
84MP0005195_abnormal_posterior_eye0.88625110
85MP0005171_absent_coat_pigmentation0.87795560
86MP0001853_heart_inflammation0.86058644
87MP0002019_abnormal_tumor_incidence0.85915934
88MP0001764_abnormal_homeostasis0.85915001
89MP0002095_abnormal_skin_pigmentation0.84587761
90MP0005671_abnormal_response_to0.84406524
91MP0000516_abnormal_urinary_system0.81588287
92MP0005367_renal/urinary_system_phenotyp0.81588287
93MP0004381_abnormal_hair_follicle0.81047656
94MP0006072_abnormal_retinal_apoptosis0.80529241
95MP0002080_prenatal_lethality0.80434853
96MP0002084_abnormal_developmental_patter0.79944141
97MP0000653_abnormal_sex_gland0.78973852
98MP0001929_abnormal_gametogenesis0.78766450
99MP0002111_abnormal_tail_morphology0.78502954
100MP0005389_reproductive_system_phenotype0.78058786
101MP0008995_early_reproductive_senescence0.77993291
102MP0003787_abnormal_imprinting0.77655268
103MP0002752_abnormal_somatic_nervous0.77554481
104MP0005187_abnormal_penis_morphology0.77267537
105MP0002277_abnormal_respiratory_mucosa0.77159629
106MP0001672_abnormal_embryogenesis/_devel0.76575701
107MP0005380_embryogenesis_phenotype0.76575701
108MP0002398_abnormal_bone_marrow0.76522043
109MP0000026_abnormal_inner_ear0.76176370
110MP0001542_abnormal_bone_strength0.75960190
111MP0001286_abnormal_eye_development0.75458094
112MP0009785_altered_susceptibility_to0.75373763
113MP0002085_abnormal_embryonic_tissue0.75322966
114MP0003861_abnormal_nervous_system0.75142259
115MP0004742_abnormal_vestibular_system0.74761693
116MP0008872_abnormal_physiological_respon0.73742453
117MP0001485_abnormal_pinna_reflex0.72556370
118MP0000015_abnormal_ear_pigmentation0.71353263
119MP0002184_abnormal_innervation0.70668453
120MP0004142_abnormal_muscle_tone0.69692703
121MP0001299_abnormal_eye_distance/0.69259805
122MP0000703_abnormal_thymus_morphology0.68873080
123MP0002722_abnormal_immune_system0.68672895
124MP0001324_abnormal_eye_pigmentation0.68508736
125MP0006276_abnormal_autonomic_nervous0.68488445
126MP0001835_abnormal_antigen_presentation0.68431873
127MP0010030_abnormal_orbit_morphology0.68400185
128MP0000358_abnormal_cell_content/0.67795160
129MP0003698_abnormal_male_reproductive0.67740339
130MP0000689_abnormal_spleen_morphology0.67669076
131MP0001293_anophthalmia0.67233628
132MP0003283_abnormal_digestive_organ0.67151272
133MP0001119_abnormal_female_reproductive0.66108450
134MP0002009_preneoplasia0.63408122
135MP0003984_embryonic_growth_retardation0.62982113
136MP0003937_abnormal_limbs/digits/tail_de0.62956114
137MP0003938_abnormal_ear_development0.62794797
138MP0002429_abnormal_blood_cell0.62044410
139MP0005379_endocrine/exocrine_gland_phen0.61214366
140MP0005174_abnormal_tail_pigmentation0.60165531

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.19762703
2Abnormality of cells of the erythroid lineage (HP:0012130)4.75061334
3Reticulocytopenia (HP:0001896)4.58830506
4Abnormal mitochondria in muscle tissue (HP:0008316)4.56865257
5Mitochondrial inheritance (HP:0001427)4.56742684
6Abnormal number of erythroid precursors (HP:0012131)4.35003334
7Progressive macrocephaly (HP:0004481)4.25420916
8Increased hepatocellular lipid droplets (HP:0006565)4.14650151
9Increased CSF lactate (HP:0002490)4.07771945
10Acute encephalopathy (HP:0006846)3.90477998
11Hepatocellular necrosis (HP:0001404)3.85676135
12Birth length less than 3rd percentile (HP:0003561)3.69592394
13Lipid accumulation in hepatocytes (HP:0006561)3.54191261
143-Methylglutaconic aciduria (HP:0003535)3.44659296
15Renal Fanconi syndrome (HP:0001994)3.38403153
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.27351270
17Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.25648505
18Decreased activity of mitochondrial respiratory chain (HP:0008972)3.25648505
19Abnormality of the labia minora (HP:0012880)3.23544234
20Macrocytic anemia (HP:0001972)3.22654478
21Hepatic necrosis (HP:0002605)3.19423023
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.15164202
23Abnormality of glycolysis (HP:0004366)3.09922496
24Increased serum pyruvate (HP:0003542)3.09922496
25Aplastic anemia (HP:0001915)3.03444708
26Increased serum lactate (HP:0002151)3.02686839
27Septo-optic dysplasia (HP:0100842)3.01206807
28Pallor (HP:0000980)2.98299629
29Exertional dyspnea (HP:0002875)2.97665391
30Breast hypoplasia (HP:0003187)2.95713819
31Exercise intolerance (HP:0003546)2.93230975
32Chromsome breakage (HP:0040012)2.89202693
33Chromosomal breakage induced by crosslinking agents (HP:0003221)2.78608436
34Cerebral hypomyelination (HP:0006808)2.76982400
35Leukodystrophy (HP:0002415)2.68481016
36Oral leukoplakia (HP:0002745)2.65385988
37Respiratory failure (HP:0002878)2.60438857
38Optic disc pallor (HP:0000543)2.56512328
39Methylmalonic acidemia (HP:0002912)2.55328657
40Respiratory difficulties (HP:0002880)2.55158847
41Increased intramyocellular lipid droplets (HP:0012240)2.46975982
42Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.45947301
43Lactic acidosis (HP:0003128)2.41586991
4411 pairs of ribs (HP:0000878)2.41291875
45Cerebral edema (HP:0002181)2.39678992
46Abnormal lung lobation (HP:0002101)2.39353299
47Duplicated collecting system (HP:0000081)2.39332925
48Abnormality of the preputium (HP:0100587)2.37116624
49Type I transferrin isoform profile (HP:0003642)2.36344590
50Colon cancer (HP:0003003)2.32791620
51Rough bone trabeculation (HP:0100670)2.32467044
52Absent septum pellucidum (HP:0001331)2.31943841
53Meckel diverticulum (HP:0002245)2.30876248
54Carpal bone hypoplasia (HP:0001498)2.29250784
55Patellar aplasia (HP:0006443)2.28232439
56Aplasia/Hypoplasia of the sacrum (HP:0008517)2.25619638
57Abnormality of the ileum (HP:0001549)2.21825666
58Abnormality of the renal collecting system (HP:0004742)2.21589096
59Medial flaring of the eyebrow (HP:0010747)2.20963905
60Nephronophthisis (HP:0000090)2.18800638
61Supernumerary spleens (HP:0009799)2.17680511
62Abnormality of renal resorption (HP:0011038)2.17183647
63Abnormality of midbrain morphology (HP:0002418)2.15709090
64Molar tooth sign on MRI (HP:0002419)2.15709090
65Absent thumb (HP:0009777)2.14011252
66Abnormality of methionine metabolism (HP:0010901)2.13053020
67Parakeratosis (HP:0001036)2.12567071
68Bilateral microphthalmos (HP:0007633)2.12557126
69Volvulus (HP:0002580)2.11009524
70Stenosis of the external auditory canal (HP:0000402)2.10659278
71Aplasia/Hypoplasia of the patella (HP:0006498)2.10399935
72Microvesicular hepatic steatosis (HP:0001414)2.08703492
73Abnormality of chromosome stability (HP:0003220)2.08533098
74Congenital, generalized hypertrichosis (HP:0004540)2.07568888
75Premature graying of hair (HP:0002216)2.07387926
76Methylmalonic aciduria (HP:0012120)2.06301380
77Abnormality of the septum pellucidum (HP:0007375)2.05775000
78Asplenia (HP:0001746)2.04012433
79Irregular epiphyses (HP:0010582)2.02933653
80Triphalangeal thumb (HP:0001199)2.00840688
81Type 2 muscle fiber atrophy (HP:0003554)1.98839889
82Absent radius (HP:0003974)1.98268734
83Hypoplasia of the capital femoral epiphysis (HP:0003090)1.97241413
84Horseshoe kidney (HP:0000085)1.97133830
85Lethargy (HP:0001254)1.96694442
86Abnormality of aspartate family amino acid metabolism (HP:0010899)1.95343807
87Sclerocornea (HP:0000647)1.93863609
88Nephroblastoma (Wilms tumor) (HP:0002667)1.90403256
89Abnormality of serum amino acid levels (HP:0003112)1.89730580
90Pancreatic cysts (HP:0001737)1.89247723
91Hypothermia (HP:0002045)1.88775135
92Intestinal atresia (HP:0011100)1.88646710
93Bone marrow hypocellularity (HP:0005528)1.88221790
94Small intestinal stenosis (HP:0012848)1.88070266
95Duodenal stenosis (HP:0100867)1.88070266
96Optic nerve hypoplasia (HP:0000609)1.87694706
97Aplasia involving forearm bones (HP:0009822)1.87598442
98Absent forearm bone (HP:0003953)1.87598442
99True hermaphroditism (HP:0010459)1.87365116
100Muscle fiber atrophy (HP:0100295)1.87307211
101Hyperglycinemia (HP:0002154)1.87066541
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.86756437
103Embryonal renal neoplasm (HP:0011794)1.86144892
104Myelodysplasia (HP:0002863)1.85976125
105Pancytopenia (HP:0001876)1.85665092
106Aplasia/Hypoplasia of the spleen (HP:0010451)1.85269536
107Increased muscle lipid content (HP:0009058)1.84719756
108Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.83466156
109Congenital primary aphakia (HP:0007707)1.83369870
110Abnormal number of incisors (HP:0011064)1.81844697
111Degeneration of anterior horn cells (HP:0002398)1.81499194
112Abnormality of the anterior horn cell (HP:0006802)1.81499194
113X-linked dominant inheritance (HP:0001423)1.81415232
114Glycosuria (HP:0003076)1.81303972
115Abnormality of urine glucose concentration (HP:0011016)1.81303972
116Abnormal trabecular bone morphology (HP:0100671)1.80207499
117Abnormality of the heme biosynthetic pathway (HP:0010472)1.79983615
118Aplasia/hypoplasia of the uterus (HP:0008684)1.79723085
119Bifid tongue (HP:0010297)1.79674048
120Anophthalmia (HP:0000528)1.79164871
121Glossoptosis (HP:0000162)1.78868288
122Gait imbalance (HP:0002141)1.78039731
123CNS demyelination (HP:0007305)1.77303169
124Pancreatic fibrosis (HP:0100732)1.77056119
125Abnormality of the duodenum (HP:0002246)1.76185518
126Genital tract atresia (HP:0001827)1.75975487
127Absent epiphyses (HP:0010577)1.75476481
128Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.75476481
129Pendular nystagmus (HP:0012043)1.74544843
130Vaginal atresia (HP:0000148)1.73843754
131Nephrogenic diabetes insipidus (HP:0009806)1.73189920
132Hyperphosphaturia (HP:0003109)1.72457456
133Cellular immunodeficiency (HP:0005374)1.72350991
134Esophageal atresia (HP:0002032)1.72139759
135Rib fusion (HP:0000902)1.72104497
136Anencephaly (HP:0002323)1.71810111
137Amniotic constriction ring (HP:0009775)1.68835548
138Abnormality of placental membranes (HP:0011409)1.68835548

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.52130706
2BUB14.43663397
3STK163.42390524
4WEE13.37488924
5EIF2AK13.14028007
6SRPK12.95702600
7NME22.86689961
8VRK12.75450978
9PBK2.66766163
10CDC72.57726152
11MST42.47585825
12NUAK12.36982983
13EIF2AK32.24172279
14WNK32.10943419
15TAF12.08320627
16MKNK12.07974153
17PLK42.06476338
18TSSK61.99381561
19NME11.94518950
20BRSK21.93972254
21ACVR1B1.90536442
22PLK31.61625138
23TRIM281.42712722
24ZAK1.41632387
25MKNK21.40456794
26MAP4K21.39435673
27PLK11.36255181
28BCR1.26973524
29CDK81.26139309
30BMPR1B1.22585496
31PASK1.22389187
32MAP3K121.21608298
33EIF2AK21.17402895
34TLK11.16785605
35TTK1.16019499
36AURKB1.15837981
37CDK71.11990472
38MYLK1.11290548
39TESK21.08067319
40ATR1.06540304
41DYRK31.06451784
42PDK21.04935549
43RPS6KB21.04081571
44CASK1.03622771
45GRK71.03257764
46CCNB11.03146862
47PIM21.00676747
48BRSK11.00488104
49AURKA0.99673632
50TGFBR10.99524648
51PNCK0.97896485
52TXK0.94341558
53DYRK20.92625762
54MUSK0.91411404
55ADRBK20.88948432
56CHEK20.87481113
57CSNK2A10.85579643
58YES10.84155715
59LIMK10.83088736
60NEK60.83048206
61MAP3K40.82082151
62CSNK1G20.81395193
63PLK20.79472759
64IRAK40.79178664
65NEK10.78189705
66CSNK2A20.77984313
67TEC0.74776497
68NEK20.73810329
69STK40.73286402
70STK240.70435903
71KDR0.69837469
72MAP2K70.69602394
73CLK10.69017498
74CSNK1G30.67939181
75ERBB30.66887581
76INSRR0.65972248
77BMPR20.65681936
78RPS6KA50.65256478
79CHEK10.63951309
80BRAF0.61736307
81EPHB20.61306049
82CSNK1A1L0.60387942
83ILK0.59728881
84OBSCN0.59603384
85TNIK0.58833946
86TESK10.57007997
87PRKCG0.56098573
88RPS6KA40.55651548
89BCKDK0.55582352
90ATM0.52163217
91CDK190.50052120
92AKT30.49261037
93MARK10.46343601
94FRK0.46326011
95MINK10.46000252
96TIE10.44458449
97ABL20.44226042
98CSNK1E0.43357832
99PAK40.42941962
100EPHA20.42473049
101STK30.41088575
102CDK10.41022812
103PAK10.40989939
104IRAK30.39117269
105PIM10.38923069
106CDK30.38059040
107ERBB40.37705487
108PINK10.37428492
109PRKCI0.37156617
110GRK10.36764419
111CDK20.36320837
112IKBKB0.35614937
113LYN0.35470805
114PRKCE0.34652650
115ALK0.33704474
116DAPK10.33583756
117WNK40.33050096
118UHMK10.32923460
119MAPKAPK50.32403253
120FGFR10.31767750
121DAPK30.30854217
122MAP3K80.30430115
123CSNK1G10.30402414
124STK38L0.29965759
125OXSR10.29656783
126MAPK130.29127784
127CSNK1A10.29040497
128STK390.28731192
129BTK0.27886706
130ADRBK10.27807713
131PRKDC0.27080657
132NLK0.26898678
133FGFR20.25819046

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.77852401
2Ribosome_Homo sapiens_hsa030104.77026676
3RNA polymerase_Homo sapiens_hsa030203.69500862
4DNA replication_Homo sapiens_hsa030303.69449257
5Oxidative phosphorylation_Homo sapiens_hsa001903.42110010
6Mismatch repair_Homo sapiens_hsa034303.37920881
7Parkinsons disease_Homo sapiens_hsa050123.07351637
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.97587484
9Spliceosome_Homo sapiens_hsa030402.93994630
10Nucleotide excision repair_Homo sapiens_hsa034202.66301518
11Homologous recombination_Homo sapiens_hsa034402.65545117
12Protein export_Homo sapiens_hsa030602.55121594
13Huntingtons disease_Homo sapiens_hsa050162.42038647
14Pyrimidine metabolism_Homo sapiens_hsa002402.41668254
15Base excision repair_Homo sapiens_hsa034102.28778639
16RNA transport_Homo sapiens_hsa030132.20788333
17Alzheimers disease_Homo sapiens_hsa050102.07566928
18Basal transcription factors_Homo sapiens_hsa030222.05350446
19Fanconi anemia pathway_Homo sapiens_hsa034601.92397741
20RNA degradation_Homo sapiens_hsa030181.85298738
21Non-homologous end-joining_Homo sapiens_hsa034501.84883025
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.74480463
23Cell cycle_Homo sapiens_hsa041101.73746172
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.62708570
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.48343673
26Purine metabolism_Homo sapiens_hsa002301.41685290
27Propanoate metabolism_Homo sapiens_hsa006401.39119580
28One carbon pool by folate_Homo sapiens_hsa006701.23355604
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.15234960
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10927589
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10342758
32mRNA surveillance pathway_Homo sapiens_hsa030151.08551933
33Epstein-Barr virus infection_Homo sapiens_hsa051691.03853472
34Cardiac muscle contraction_Homo sapiens_hsa042600.98553599
35Selenocompound metabolism_Homo sapiens_hsa004500.97793997
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.96985209
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.96539879
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89102694
39p53 signaling pathway_Homo sapiens_hsa041150.86151082
40Graft-versus-host disease_Homo sapiens_hsa053320.78376208
41SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78322765
42Butanoate metabolism_Homo sapiens_hsa006500.77954574
43Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75423298
44Glutathione metabolism_Homo sapiens_hsa004800.72918868
45Systemic lupus erythematosus_Homo sapiens_hsa053220.71294363
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69936783
47Basal cell carcinoma_Homo sapiens_hsa052170.65623223
48Allograft rejection_Homo sapiens_hsa053300.65493767
49Antigen processing and presentation_Homo sapiens_hsa046120.63929415
50Primary immunodeficiency_Homo sapiens_hsa053400.63547581
51Peroxisome_Homo sapiens_hsa041460.59408553
52Nitrogen metabolism_Homo sapiens_hsa009100.57556065
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57145443
54Herpes simplex infection_Homo sapiens_hsa051680.54522710
55Arachidonic acid metabolism_Homo sapiens_hsa005900.54469132
56Collecting duct acid secretion_Homo sapiens_hsa049660.53911008
57Autoimmune thyroid disease_Homo sapiens_hsa053200.53490238
58Fatty acid elongation_Homo sapiens_hsa000620.52969352
59Asthma_Homo sapiens_hsa053100.52486439
60Carbon metabolism_Homo sapiens_hsa012000.51939692
61Oocyte meiosis_Homo sapiens_hsa041140.51838107
62Nicotine addiction_Homo sapiens_hsa050330.50892368
63Metabolic pathways_Homo sapiens_hsa011000.49592285
64Hedgehog signaling pathway_Homo sapiens_hsa043400.49217311
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46731037
66Tryptophan metabolism_Homo sapiens_hsa003800.45399139
67Rheumatoid arthritis_Homo sapiens_hsa053230.45141934
68Biosynthesis of amino acids_Homo sapiens_hsa012300.45021392
69Sulfur metabolism_Homo sapiens_hsa009200.44772152
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44738475
71Vibrio cholerae infection_Homo sapiens_hsa051100.42355491
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.42263320
73Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41793963
74Chemical carcinogenesis_Homo sapiens_hsa052040.41612540
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41509173
76Legionellosis_Homo sapiens_hsa051340.41229825
77Type I diabetes mellitus_Homo sapiens_hsa049400.40810433
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38210701
79beta-Alanine metabolism_Homo sapiens_hsa004100.37838136
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37275384
81Viral carcinogenesis_Homo sapiens_hsa052030.37147703
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36909257
83Hematopoietic cell lineage_Homo sapiens_hsa046400.36237335
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35770508
85Steroid biosynthesis_Homo sapiens_hsa001000.33619111
86Phototransduction_Homo sapiens_hsa047440.32000499
87Caffeine metabolism_Homo sapiens_hsa002320.31746195
88Alcoholism_Homo sapiens_hsa050340.31695028
89Intestinal immune network for IgA production_Homo sapiens_hsa046720.31190035
90Sulfur relay system_Homo sapiens_hsa041220.30390755
91Phagosome_Homo sapiens_hsa041450.30368601
92Vitamin digestion and absorption_Homo sapiens_hsa049770.29711266
93Olfactory transduction_Homo sapiens_hsa047400.28720144
94Taste transduction_Homo sapiens_hsa047420.27892480
95Fatty acid degradation_Homo sapiens_hsa000710.27365053
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27308519
97Folate biosynthesis_Homo sapiens_hsa007900.27265243
98Retinol metabolism_Homo sapiens_hsa008300.26594891
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26188122
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.25776468
101Fatty acid metabolism_Homo sapiens_hsa012120.25644171
102Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.25592680
103HTLV-I infection_Homo sapiens_hsa051660.25313160
104Wnt signaling pathway_Homo sapiens_hsa043100.25105412
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24671297
106Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22895488
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.21530217
108Ether lipid metabolism_Homo sapiens_hsa005650.21284392
109Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.20740414
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.20676518
111Drug metabolism - other enzymes_Homo sapiens_hsa009830.19140644
112Measles_Homo sapiens_hsa051620.18742524
113Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.18028361
114TGF-beta signaling pathway_Homo sapiens_hsa043500.16933757
115N-Glycan biosynthesis_Homo sapiens_hsa005100.16797017
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.16620184
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.16511661
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.16336813
119Linoleic acid metabolism_Homo sapiens_hsa005910.15988283
120Arginine and proline metabolism_Homo sapiens_hsa003300.15784367
121NOD-like receptor signaling pathway_Homo sapiens_hsa046210.15368285
122Hippo signaling pathway_Homo sapiens_hsa043900.14915131
123Sphingolipid metabolism_Homo sapiens_hsa006000.12578364
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.12201045
125Transcriptional misregulation in cancer_Homo sapiens_hsa052020.12066180
126Pentose phosphate pathway_Homo sapiens_hsa000300.11999715
127Shigellosis_Homo sapiens_hsa051310.11099507
128Cyanoamino acid metabolism_Homo sapiens_hsa004600.08474605
129Apoptosis_Homo sapiens_hsa042100.08241497
130Malaria_Homo sapiens_hsa051440.07189431
131Regulation of autophagy_Homo sapiens_hsa041400.06097664
132Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.03049154
133RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.02537322
134Vitamin B6 metabolism_Homo sapiens_hsa007500.02334188
135Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.01700685
136Tyrosine metabolism_Homo sapiens_hsa003500.00420687
137Pyruvate metabolism_Homo sapiens_hsa00620-0.0182293
138Pathways in cancer_Homo sapiens_hsa05200-0.0099193
139Serotonergic synapse_Homo sapiens_hsa04726-0.0079813
140Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514-0.0038992

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