SAT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)6.13419087
2central nervous system myelination (GO:0022010)6.13419087
3fatty acid elongation (GO:0030497)4.99490354
4pyrimidine nucleobase catabolic process (GO:0006208)4.86289298
5nucleobase catabolic process (GO:0046113)4.36404462
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.04204141
7L-phenylalanine catabolic process (GO:0006559)4.04204141
8mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.03691858
9long-chain fatty acid biosynthetic process (GO:0042759)3.91889853
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.84984798
11myelination (GO:0042552)3.61470397
12ATP synthesis coupled proton transport (GO:0015986)3.59699317
13energy coupled proton transport, down electrochemical gradient (GO:0015985)3.59699317
14cholesterol biosynthetic process (GO:0006695)3.56020668
15epoxygenase P450 pathway (GO:0019373)3.55589285
16axon ensheathment (GO:0008366)3.53163187
17ensheathment of neurons (GO:0007272)3.53163187
18L-phenylalanine metabolic process (GO:0006558)3.50048227
19erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.50048227
20chaperone-mediated protein transport (GO:0072321)3.41971427
21regulation of triglyceride catabolic process (GO:0010896)3.39904353
22substrate-independent telencephalic tangential migration (GO:0021826)3.39874341
23substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.39874341
24regulation of cholesterol esterification (GO:0010872)3.37940640
25dopamine biosynthetic process (GO:0042416)3.35411280
26C4-dicarboxylate transport (GO:0015740)3.27758772
27respiratory electron transport chain (GO:0022904)3.27609889
28neuron cell-cell adhesion (GO:0007158)3.23488451
29high-density lipoprotein particle remodeling (GO:0034375)3.21131663
30drug catabolic process (GO:0042737)3.19086292
31neuron fate determination (GO:0048664)3.18856817
32electron transport chain (GO:0022900)3.18050461
33response to methylmercury (GO:0051597)3.17577050
34sterol biosynthetic process (GO:0016126)3.15387960
35postsynaptic membrane organization (GO:0001941)3.14077976
36drug metabolic process (GO:0017144)3.10855785
37dendritic spine morphogenesis (GO:0060997)3.10699357
38substantia nigra development (GO:0021762)3.07585896
39phospholipid efflux (GO:0033700)3.06871470
40glyoxylate metabolic process (GO:0046487)3.06027678
41response to redox state (GO:0051775)3.05919142
42regulation of dopamine metabolic process (GO:0042053)3.03837831
43regulation of catecholamine metabolic process (GO:0042069)3.03837831
44viral transcription (GO:0019083)3.03553670
45short-term memory (GO:0007614)3.01319363
46negative regulation of protein localization to cell surface (GO:2000009)3.01137390
47behavioral response to nicotine (GO:0035095)3.00028592
48neuron recognition (GO:0008038)2.99767986
49negative regulation of neurotransmitter transport (GO:0051589)2.98498292
50very long-chain fatty acid metabolic process (GO:0000038)2.96939782
51L-amino acid import (GO:0043092)2.96457718
52neurotransmitter catabolic process (GO:0042135)2.95126542
53reverse cholesterol transport (GO:0043691)2.92506481
54negative regulation of synaptic transmission, GABAergic (GO:0032229)2.90510856
55negative regulation of sterol transport (GO:0032372)2.89551292
56negative regulation of cholesterol transport (GO:0032375)2.89551292
57establishment of mitochondrion localization (GO:0051654)2.89414006
58triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.88996907
59exogenous drug catabolic process (GO:0042738)2.87941245
60epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.87003892
61neurotransmitter uptake (GO:0001504)2.86950462
62arginine metabolic process (GO:0006525)2.85801874
63translational termination (GO:0006415)2.82593807
64positive regulation of triglyceride lipase activity (GO:0061365)2.79584983
65positive regulation of lipoprotein lipase activity (GO:0051006)2.79584983
66presynaptic membrane assembly (GO:0097105)2.75619582
67presynaptic membrane organization (GO:0097090)2.74187719
68virion attachment to host cell (GO:0019062)2.73001707
69adhesion of symbiont to host cell (GO:0044650)2.73001707
70regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.71770194
71cholesterol efflux (GO:0033344)2.71513644
72cell migration in hindbrain (GO:0021535)2.71264907
73oligodendrocyte differentiation (GO:0048709)2.70355456
74protein neddylation (GO:0045116)2.69580315
75aromatic amino acid family catabolic process (GO:0009074)2.68309025
76fat-soluble vitamin biosynthetic process (GO:0042362)2.66095522
77coenzyme catabolic process (GO:0009109)2.65148366
78synaptic vesicle exocytosis (GO:0016079)2.64918878
79gamma-aminobutyric acid transport (GO:0015812)2.63541406
80iron coordination entity transport (GO:1901678)2.63091339
81amino acid import (GO:0043090)2.62562359
82protein-lipid complex remodeling (GO:0034368)2.61798187
83macromolecular complex remodeling (GO:0034367)2.61798187
84plasma lipoprotein particle remodeling (GO:0034369)2.61798187
85long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.61592615
86isoprenoid biosynthetic process (GO:0008299)2.61178430
87nonmotile primary cilium assembly (GO:0035058)2.61094188
88retinal ganglion cell axon guidance (GO:0031290)2.60730440
89establishment of protein localization to mitochondrial membrane (GO:0090151)2.58882690
90ethanol oxidation (GO:0006069)2.56017917
91vitamin biosynthetic process (GO:0009110)2.55508010
92regulation of collateral sprouting (GO:0048670)2.53503346
93nucleotide transmembrane transport (GO:1901679)2.53276281
94glycerophospholipid catabolic process (GO:0046475)2.53128429
95cellular ketone body metabolic process (GO:0046950)2.52416730
96heme transport (GO:0015886)2.51946510
97omega-hydroxylase P450 pathway (GO:0097267)2.49296957
98arginine catabolic process (GO:0006527)2.47612419
99fatty-acyl-CoA biosynthetic process (GO:0046949)2.46010845
100gamma-aminobutyric acid signaling pathway (GO:0007214)2.45755786
101water-soluble vitamin biosynthetic process (GO:0042364)2.44920498
102neuronal action potential propagation (GO:0019227)2.44504270
103myelin maintenance (GO:0043217)2.44459160
104positive regulation of action potential (GO:0045760)2.44124131
105limb bud formation (GO:0060174)2.44007916
106positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.43709068
107cotranslational protein targeting to membrane (GO:0006613)2.42886761
108peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.42746431
109protein targeting to ER (GO:0045047)2.42660291
110auditory receptor cell differentiation (GO:0042491)2.42617857
111long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.42042106
112energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.41750453
113ATP hydrolysis coupled proton transport (GO:0015991)2.41750453
114tyrosine metabolic process (GO:0006570)2.41731198
115epithelial cilium movement (GO:0003351)2.41639902
116SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.40257118
117protein localization to endoplasmic reticulum (GO:0070972)2.39776470
118phenylpropanoid metabolic process (GO:0009698)2.39613197
119fatty-acyl-CoA metabolic process (GO:0035337)2.39596274
120very-low-density lipoprotein particle assembly (GO:0034379)2.39432372
121complement activation, alternative pathway (GO:0006957)2.37447539
122peroxisome fission (GO:0016559)2.36318761
123myelination in peripheral nervous system (GO:0022011)2.35535707
124peripheral nervous system axon ensheathment (GO:0032292)2.35535707
125regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.34790941
126negative regulation of neurotransmitter secretion (GO:0046929)2.34641882
127apical protein localization (GO:0045176)2.34490277
128bile acid biosynthetic process (GO:0006699)2.34218642
129protein carboxylation (GO:0018214)2.33851525
130peptidyl-glutamic acid carboxylation (GO:0017187)2.33851525
131viral protein processing (GO:0019082)2.33297738
132plasma lipoprotein particle assembly (GO:0034377)2.33139535
133dopamine transport (GO:0015872)2.32328904
134synaptic transmission, cholinergic (GO:0007271)2.32146714
135sequestering of actin monomers (GO:0042989)2.31886809
136axon extension (GO:0048675)2.31490445
137response to epinephrine (GO:0071871)2.31423473
138bile acid metabolic process (GO:0008206)2.30629552
139negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.30294566
140establishment of protein localization to endoplasmic reticulum (GO:0072599)2.30233601
141establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.27245216
142mitochondrion transport along microtubule (GO:0047497)2.27245216
143triglyceride homeostasis (GO:0070328)2.27165639
144acylglycerol homeostasis (GO:0055090)2.27165639
145protein complex biogenesis (GO:0070271)2.27016496
146fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.26901326
147adhesion of symbiont to host (GO:0044406)2.25375502
148L-ascorbic acid metabolic process (GO:0019852)2.24126295
149thalamus development (GO:0021794)2.23676187
150viral life cycle (GO:0019058)2.23575638
151protein localization to synapse (GO:0035418)2.23493957
152neuron remodeling (GO:0016322)2.23060010
153transmission of nerve impulse (GO:0019226)2.22958031
154aldehyde catabolic process (GO:0046185)2.21643306
155axonal fasciculation (GO:0007413)2.21576779
156regulation of glutamate secretion (GO:0014048)2.21255265
157diacylglycerol metabolic process (GO:0046339)2.21222467
158fat-soluble vitamin metabolic process (GO:0006775)2.21152763
159thioester biosynthetic process (GO:0035384)2.20485029
160acyl-CoA biosynthetic process (GO:0071616)2.20485029
161photoreceptor cell differentiation (GO:0046530)2.20245772
162eye photoreceptor cell differentiation (GO:0001754)2.20245772
163ketone body metabolic process (GO:1902224)2.20053301
164mechanosensory behavior (GO:0007638)2.19522390
165hydrogen ion transmembrane transport (GO:1902600)2.18291088
166mitochondrial respiratory chain complex I assembly (GO:0032981)2.17825711
167NADH dehydrogenase complex assembly (GO:0010257)2.17825711
168mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.17825711
169positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.17361078
170regulation of amyloid precursor protein catabolic process (GO:1902991)2.16981752
171adult walking behavior (GO:0007628)2.15486049
172catecholamine biosynthetic process (GO:0042423)2.15456645
173catechol-containing compound biosynthetic process (GO:0009713)2.15456645
174synaptic transmission, glutamatergic (GO:0035249)2.14713976
175ionotropic glutamate receptor signaling pathway (GO:0035235)2.14190951
176neural nucleus development (GO:0048857)2.13249399
177cofactor catabolic process (GO:0051187)2.12717673
178regulation of pigment cell differentiation (GO:0050932)2.11877566
179neuron-neuron synaptic transmission (GO:0007270)2.11703751

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.06209944
2GBX2_23144817_ChIP-Seq_PC3_Human3.69014790
3EZH2_22144423_ChIP-Seq_EOC_Human3.36478720
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.61791249
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.60886122
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.55304170
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.33032120
8AR_21572438_ChIP-Seq_LNCaP_Human2.32331124
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.28951883
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.27920187
11TAF15_26573619_Chip-Seq_HEK293_Human2.24833342
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.18731455
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.17553597
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.15788023
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.11852220
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.11852220
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.11735777
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.09770467
19JARID2_20075857_ChIP-Seq_MESCs_Mouse2.02006771
20SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.00988934
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.98558882
22MTF2_20144788_ChIP-Seq_MESCs_Mouse1.98258462
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.94536768
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.93441642
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.91046838
26IKZF1_21737484_ChIP-ChIP_HCT116_Human1.90454852
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.79417693
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.78932870
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.76933203
30CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.74823593
31P300_19829295_ChIP-Seq_ESCs_Human1.74513978
32PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.74069349
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.72698374
34SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72449248
35* CTCF_27219007_Chip-Seq_Bcells_Human1.71499393
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.68065502
37VDR_22108803_ChIP-Seq_LS180_Human1.67706042
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.66358369
39FUS_26573619_Chip-Seq_HEK293_Human1.64807417
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.63229942
41RNF2_27304074_Chip-Seq_ESCs_Mouse1.59812710
42SRY_22984422_ChIP-ChIP_TESTIS_Rat1.59012985
43PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.58062048
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56462778
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.54785215
46REST_21632747_ChIP-Seq_MESCs_Mouse1.52763310
47NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51384936
48ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.47241929
49TP53_20018659_ChIP-ChIP_R1E_Mouse1.45599909
50ER_23166858_ChIP-Seq_MCF-7_Human1.45459061
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.44200419
52E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.44120721
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.43428937
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42984328
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.39763278
56DNAJC2_21179169_ChIP-ChIP_NT2_Human1.39106549
57SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.36818261
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36011222
59SMAD4_21799915_ChIP-Seq_A2780_Human1.35057956
60OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.34032846
61LXR_22292898_ChIP-Seq_THP-1_Human1.33225505
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31263750
63SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31160453
64SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.30778760
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30285246
66HTT_18923047_ChIP-ChIP_STHdh_Human1.29656306
67* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.28657855
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28190365
69* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.24911053
70SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.23263609
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22448890
72REST_18959480_ChIP-ChIP_MESCs_Mouse1.22257048
73SA1_27219007_Chip-Seq_Bcells_Human1.20649974
74NRF2_20460467_ChIP-Seq_MEFs_Mouse1.19995104
75NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.19995104
76PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.18837661
77RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15930088
78ETV2_25802403_ChIP-Seq_MESCs_Mouse1.15310938
79NR3C1_23031785_ChIP-Seq_PC12_Mouse1.14297637
80DROSHA_22980978_ChIP-Seq_HELA_Human1.08874577
81AR_25329375_ChIP-Seq_VCAP_Human1.08743914
82CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.08396265
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07786983
84BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.07496685
85TET1_21451524_ChIP-Seq_MESCs_Mouse1.07325659
86ERG_21242973_ChIP-ChIP_JURKAT_Human1.06638922
87* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06493062
88WT1_19549856_ChIP-ChIP_CCG9911_Human1.05910219
89ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.05570334
90STAT3_23295773_ChIP-Seq_U87_Human1.05366253
91RNF2_27304074_Chip-Seq_NSC_Mouse1.04604397
92NANOG_18555785_Chip-Seq_ESCs_Mouse1.04600745
93PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.03972764
94SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03550933
95EP300_21415370_ChIP-Seq_HL-1_Mouse1.02599452
96PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.02244279
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02237502
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02152570
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.01545286
100STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.00570625
101FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.00524254
102EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00442913
103RUNX2_22187159_ChIP-Seq_PCA_Human0.99796947
104RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99525474
105HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99026247
106BCL6_27268052_Chip-Seq_Bcells_Human0.98282221
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97911333
108TAL1_26923725_Chip-Seq_HPCs_Mouse0.97564490
109RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95765082
110* TAF2_19829295_ChIP-Seq_ESCs_Human0.94970326
111POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94892183
112RXR_22158963_ChIP-Seq_LIVER_Mouse0.94669793
113CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.94552854
114JUN_21703547_ChIP-Seq_K562_Human0.94529246
115RARB_27405468_Chip-Seq_BRAIN_Mouse0.94392719
116CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.93631983
117PPARA_22158963_ChIP-Seq_LIVER_Mouse0.93604777
118SOX2_19829295_ChIP-Seq_ESCs_Human0.93493745
119NANOG_19829295_ChIP-Seq_ESCs_Human0.93493745
120BCAT_22108803_ChIP-Seq_LS180_Human0.92997028
121* CTCF_20526341_ChIP-Seq_ESCs_Human0.92698925
122ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.92634871
123ERA_21632823_ChIP-Seq_H3396_Human0.92356897
124PRDM14_20953172_ChIP-Seq_ESCs_Human0.91540916
125RING1B_27294783_Chip-Seq_ESCs_Mouse0.91479464
126TCF4_23295773_ChIP-Seq_U87_Human0.91311899
127SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90784430
128EGR1_23403033_ChIP-Seq_LIVER_Mouse0.90636838
129EWS_26573619_Chip-Seq_HEK293_Human0.90295448
130NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.90206219
131OCT4_19829295_ChIP-Seq_ESCs_Human0.89923636
132* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.89756105
133TRIM28_21343339_ChIP-Seq_HEK293_Human0.89702184
134CMYC_18555785_Chip-Seq_ESCs_Mouse0.89326431
135LXR_22158963_ChIP-Seq_LIVER_Mouse0.88528440
136P53_22387025_ChIP-Seq_ESCs_Mouse0.87294354
137SOX2_21211035_ChIP-Seq_LN229_Human0.86550564
138CTCF_18555785_ChIP-Seq_MESCs_Mouse0.84536288
139* SA1_27219007_Chip-Seq_ERYTHROID_Human0.84100851
140* PHF8_20622854_ChIP-Seq_HELA_Human0.82979054
141MYC_19829295_ChIP-Seq_ESCs_Human0.82212549
142OCT4_18692474_ChIP-Seq_MEFs_Mouse0.82062456
143PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81915761
144* BCOR_27268052_Chip-Seq_Bcells_Human0.81602149
145* P68_20966046_ChIP-Seq_HELA_Human0.80947923
146EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.80517385
147* YY1_22570637_ChIP-Seq_MALME-3M_Human0.80192804
148STAT1_20625510_ChIP-Seq_HELA_Human0.79924917
149NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.79642637
150ZFP281_18757296_ChIP-ChIP_E14_Mouse0.79229049
151SMC4_20622854_ChIP-Seq_HELA_Human0.79203442
152* NANOG_20526341_ChIP-Seq_ESCs_Human0.79069119
153SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.77393098
154FOXH1_21741376_ChIP-Seq_ESCs_Human0.77187352
155KDM2B_26808549_Chip-Seq_K562_Human0.76679500
156* E2F1_20622854_ChIP-Seq_HELA_Human0.76615793
157FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.76319552
158EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.75791525
159* ELF1_20517297_ChIP-Seq_JURKAT_Human0.75487984
160RING1B_27294783_Chip-Seq_NPCs_Mouse0.75226910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.79324814
2MP0009379_abnormal_foot_pigmentation3.09262420
3MP0009840_abnormal_foam_cell2.88571464
4MP0001529_abnormal_vocalization2.76735616
5MP0002653_abnormal_ependyma_morphology2.62981032
6MP0006292_abnormal_olfactory_placode2.61211196
7MP0001905_abnormal_dopamine_level2.41116307
8MP0004858_abnormal_nervous_system2.40591146
9MP0004270_analgesia2.32746117
10MP0004859_abnormal_synaptic_plasticity2.29735725
11MP0002064_seizures2.29189412
12MP0000920_abnormal_myelination2.26420306
13MP0005360_urolithiasis2.22990400
14MP0003011_delayed_dark_adaptation2.15380710
15MP0003806_abnormal_nucleotide_metabolis2.10946689
16MP0009745_abnormal_behavioral_response2.09641386
17MP0002139_abnormal_hepatobiliary_system2.07676976
18MP0003635_abnormal_synaptic_transmissio2.05800990
19MP0001486_abnormal_startle_reflex2.02447233
20MP0002272_abnormal_nervous_system2.00215917
21MP0003329_amyloid_beta_deposits1.96060442
22MP0004742_abnormal_vestibular_system1.91491233
23MP0002138_abnormal_hepatobiliary_system1.90873629
24MP0003787_abnormal_imprinting1.89851373
25MP0009046_muscle_twitch1.87329672
26MP0001440_abnormal_grooming_behavior1.87303268
27MP0003123_paternal_imprinting1.82835600
28MP0001968_abnormal_touch/_nociception1.82442710
29MP0004142_abnormal_muscle_tone1.80542726
30MP0003122_maternal_imprinting1.80506222
31MP0000778_abnormal_nervous_system1.78262119
32MP0002736_abnormal_nociception_after1.78047472
33MP0002837_dystrophic_cardiac_calcinosis1.75569635
34MP0004019_abnormal_vitamin_homeostasis1.75024799
35MP0002572_abnormal_emotion/affect_behav1.74519779
36MP0003690_abnormal_glial_cell1.73134762
37MP0006276_abnormal_autonomic_nervous1.70901963
38MP0002734_abnormal_mechanical_nocicepti1.69313089
39MP0002063_abnormal_learning/memory/cond1.67365331
40MP0003136_yellow_coat_color1.62925070
41MP0000566_synostosis1.53508696
42MP0008875_abnormal_xenobiotic_pharmacok1.53062349
43MP0002822_catalepsy1.51703509
44MP0005551_abnormal_eye_electrophysiolog1.51394548
45MP0005646_abnormal_pituitary_gland1.51262566
46MP0005085_abnormal_gallbladder_physiolo1.48734061
47MP0005645_abnormal_hypothalamus_physiol1.48203484
48MP0003121_genomic_imprinting1.47349225
49MP0002067_abnormal_sensory_capabilities1.46193536
50MP0003195_calcinosis1.44223637
51MP0002733_abnormal_thermal_nociception1.41708253
52MP0004885_abnormal_endolymph1.39655124
53MP0005365_abnormal_bile_salt1.39433247
54MP0003634_abnormal_glial_cell1.38291418
55MP0004924_abnormal_behavior1.37222403
56MP0005386_behavior/neurological_phenoty1.37222403
57MP0005171_absent_coat_pigmentation1.35869836
58MP0008789_abnormal_olfactory_epithelium1.34949284
59MP0002938_white_spotting1.31405778
60MP0009384_cardiac_valve_regurgitation1.30429475
61MP0001970_abnormal_pain_threshold1.30326408
62MP0002638_abnormal_pupillary_reflex1.29981597
63MP0010329_abnormal_lipoprotein_level1.29567562
64MP0005332_abnormal_amino_acid1.29285034
65MP0002735_abnormal_chemical_nociception1.28909554
66MP0001986_abnormal_taste_sensitivity1.28855788
67MP0005394_taste/olfaction_phenotype1.28196920
68MP0005499_abnormal_olfactory_system1.28196920
69MP0002229_neurodegeneration1.25691585
70MP0001984_abnormal_olfaction1.21485233
71MP0005408_hypopigmentation1.20816324
72MP0001485_abnormal_pinna_reflex1.20339889
73MP0000955_abnormal_spinal_cord1.18441672
74MP0002277_abnormal_respiratory_mucosa1.16708084
75MP0003950_abnormal_plasma_membrane1.16403985
76MP0001963_abnormal_hearing_physiology1.16175269
77MP0005503_abnormal_tendon_morphology1.15579148
78MP0002184_abnormal_innervation1.14164201
79MP0001502_abnormal_circadian_rhythm1.12968655
80MP0004043_abnormal_pH_regulation1.12786568
81MP0003632_abnormal_nervous_system1.10855405
82MP0002066_abnormal_motor_capabilities/c1.10559317
83MP0001666_abnormal_nutrient_absorption1.09645568
84MP0003938_abnormal_ear_development1.09214450
85MP0002557_abnormal_social/conspecific_i1.08443410
86MP0002882_abnormal_neuron_morphology1.08172648
87MP0005058_abnormal_lysosome_morphology1.06446396
88MP0004145_abnormal_muscle_electrophysio1.06406376
89MP0005409_darkened_coat_color1.03831197
90MP0000013_abnormal_adipose_tissue1.02737473
91MP0003631_nervous_system_phenotype1.02442582
92MP0005377_hearing/vestibular/ear_phenot0.99807922
93MP0003878_abnormal_ear_physiology0.99807922
94MP0005379_endocrine/exocrine_gland_phen0.99792039
95MP0005451_abnormal_body_composition0.99731291
96MP0005084_abnormal_gallbladder_morpholo0.99688099
97MP0000049_abnormal_middle_ear0.99299598
98MP0010386_abnormal_urinary_bladder0.98662249
99MP0000026_abnormal_inner_ear0.96564919
100MP0000604_amyloidosis0.96260837
101MP0001501_abnormal_sleep_pattern0.94855278
102MP0003633_abnormal_nervous_system0.94784469
103MP0001764_abnormal_homeostasis0.94400789
104MP0005423_abnormal_somatic_nervous0.93939241
105MP0004133_heterotaxia0.93450386
106MP0003075_altered_response_to0.92028046
107MP0003186_abnormal_redox_activity0.91597861
108MP0002090_abnormal_vision0.91237232
109MP0002909_abnormal_adrenal_gland0.91033085
110MP0004134_abnormal_chest_morphology0.90838015
111MP0002752_abnormal_somatic_nervous0.90592249
112MP0000747_muscle_weakness0.87335073
113MP0002295_abnormal_pulmonary_circulatio0.86449260
114MP0005535_abnormal_body_temperature0.84091414
115MP0001188_hyperpigmentation0.82601973
116MP0002118_abnormal_lipid_homeostasis0.80801279
117MP0001661_extended_life_span0.80399708
118MP0000372_irregular_coat_pigmentation0.79540891
119MP0008438_abnormal_cutaneous_collagen0.79252997
120MP0000631_abnormal_neuroendocrine_gland0.78803461
121MP0003879_abnormal_hair_cell0.78732814
122MP0000462_abnormal_digestive_system0.78160747
123MP0003283_abnormal_digestive_organ0.77725675
124MP0005448_abnormal_energy_balance0.77031024
125MP0005248_abnormal_Harderian_gland0.76059728
126MP0002876_abnormal_thyroid_physiology0.75673806
127MP0006072_abnormal_retinal_apoptosis0.75414455
128MP0005195_abnormal_posterior_eye0.75203309
129MP0001324_abnormal_eye_pigmentation0.74950792
130MP0005410_abnormal_fertilization0.74658741
131MP0002069_abnormal_eating/drinking_beha0.74477233
132MP0002152_abnormal_brain_morphology0.74300360
133MP0004811_abnormal_neuron_physiology0.73338655
134MP0005595_abnormal_vascular_smooth0.72532130
135MP0001177_atelectasis0.71393071
136MP0008569_lethality_at_weaning0.70362495
137MP0000749_muscle_degeneration0.69870083

Predicted human phenotypes

RankGene SetZ-score
1Polyphagia (HP:0002591)4.45062511
2Neurofibrillary tangles (HP:0002185)3.89607123
3Systemic lupus erythematosus (HP:0002725)3.89014681
4Acute necrotizing encephalopathy (HP:0006965)3.88361314
5Acute encephalopathy (HP:0006846)3.67084062
6Abnormality of glycolysis (HP:0004366)3.44770289
7Increased serum pyruvate (HP:0003542)3.44770289
8Abnormal mitochondria in muscle tissue (HP:0008316)3.43473328
9Mitochondrial inheritance (HP:0001427)3.31027223
10Renal Fanconi syndrome (HP:0001994)3.29623545
11Cerebral inclusion bodies (HP:0100314)3.29427413
12Abnormality of aromatic amino acid family metabolism (HP:0004338)3.25447838
13Progressive macrocephaly (HP:0004481)3.20016811
14Failure to thrive in infancy (HP:0001531)3.16452410
15Abnormal eating behavior (HP:0100738)3.05823518
16Degeneration of the lateral corticospinal tracts (HP:0002314)3.00681585
17Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.00681585
18Molar tooth sign on MRI (HP:0002419)2.97154366
19Abnormality of midbrain morphology (HP:0002418)2.97154366
20Hyperventilation (HP:0002883)2.96699815
21Gait imbalance (HP:0002141)2.96556897
22Parakeratosis (HP:0001036)2.92542652
23Complement deficiency (HP:0004431)2.92070840
24Poor suck (HP:0002033)2.90343470
25Pancreatic fibrosis (HP:0100732)2.86184276
26Focal motor seizures (HP:0011153)2.82803190
27Leukodystrophy (HP:0002415)2.82601445
28Hepatocellular necrosis (HP:0001404)2.78926277
29Increased hepatocellular lipid droplets (HP:0006565)2.70000371
30Hypobetalipoproteinemia (HP:0003563)2.65229698
31Cerebral edema (HP:0002181)2.61507020
32Congenital primary aphakia (HP:0007707)2.61471454
33Increased CSF lactate (HP:0002490)2.59222458
34Abnormality of glutamine family amino acid metabolism (HP:0010902)2.57326510
35Pheochromocytoma (HP:0002666)2.54851318
36Retinal dysplasia (HP:0007973)2.53915761
37Lipid accumulation in hepatocytes (HP:0006561)2.53368865
38Nephrogenic diabetes insipidus (HP:0009806)2.50883625
39Hyperphosphaturia (HP:0003109)2.48499356
40Autoamputation (HP:0001218)2.47297271
41Hypoplastic left heart (HP:0004383)2.47138702
42Hepatic necrosis (HP:0002605)2.43390678
43Pancreatic cysts (HP:0001737)2.42694787
44True hermaphroditism (HP:0010459)2.42104206
45Abnormality of monocarboxylic acid metabolism (HP:0010996)2.41357997
463-Methylglutaconic aciduria (HP:0003535)2.40835926
47Sensory axonal neuropathy (HP:0003390)2.40594988
48Agitation (HP:0000713)2.39219346
49Myokymia (HP:0002411)2.36590567
50Neuroendocrine neoplasm (HP:0100634)2.35657740
51Septo-optic dysplasia (HP:0100842)2.34149529
52Oligomenorrhea (HP:0000876)2.31631335
53Status epilepticus (HP:0002133)2.30842204
54Abnormality of the corticospinal tract (HP:0002492)2.30681852
55Limb dystonia (HP:0002451)2.29820259
56Abnormality of renal resorption (HP:0011038)2.27258135
57Prolonged partial thromboplastin time (HP:0003645)2.25571016
58Delayed CNS myelination (HP:0002188)2.24919396
59Retinal atrophy (HP:0001105)2.23432384
60Enlarged kidneys (HP:0000105)2.22864065
61Mutism (HP:0002300)2.20494265
62Abnormality of magnesium homeostasis (HP:0004921)2.20402344
63Reticulocytopenia (HP:0001896)2.20185264
64Supranuclear gaze palsy (HP:0000605)2.20108515
65Abnormal gallbladder physiology (HP:0012438)2.19739256
66Cholecystitis (HP:0001082)2.19739256
67Optic disc pallor (HP:0000543)2.18211234
68Hemiparesis (HP:0001269)2.16368323
69Hypoplastic pelvis (HP:0008839)2.15493399
70Cystic liver disease (HP:0006706)2.15284102
71Nephronophthisis (HP:0000090)2.15117309
72Respiratory failure (HP:0002878)2.14688717
73Epileptic encephalopathy (HP:0200134)2.13337429
74Prolonged neonatal jaundice (HP:0006579)2.12760084
75Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.12717318
76Spastic paraparesis (HP:0002313)2.10766540
77Hyperlipoproteinemia (HP:0010980)2.09240810
78Sleep apnea (HP:0010535)2.06308416
79Glomerulonephritis (HP:0000099)2.06307961
80Delusions (HP:0000746)2.05140231
81Sclerocornea (HP:0000647)2.04839502
82Abnormality of complement system (HP:0005339)2.04408621
83Myelomeningocele (HP:0002475)2.03804699
84Hypoplastic heart (HP:0001961)2.02948233
85Abnormal urine phosphate concentration (HP:0012599)2.01255263
86Atonic seizures (HP:0010819)1.98499707
87Cerebral hypomyelination (HP:0006808)1.97738976
88Dysmetria (HP:0001310)1.97402785
89Intrahepatic cholestasis (HP:0001406)1.95639790
90Macrocytic anemia (HP:0001972)1.95150926
91Abnormal rod and cone electroretinograms (HP:0008323)1.94747444
92Cerebral hemorrhage (HP:0001342)1.93233648
93Hyperglycinuria (HP:0003108)1.93062086
94Increased intramyocellular lipid droplets (HP:0012240)1.92959587
95Protuberant abdomen (HP:0001538)1.91092574
96Hyperglycinemia (HP:0002154)1.90686530
97Abnormality of the vitreous humor (HP:0004327)1.90605788
98Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.89633219
99Confusion (HP:0001289)1.88624037
100Spastic tetraplegia (HP:0002510)1.88543220
101Type II lissencephaly (HP:0007260)1.87270899
102X-linked dominant inheritance (HP:0001423)1.87253006
103Abnormality of the labia minora (HP:0012880)1.87219061
104Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.87214683
105Methylmalonic acidemia (HP:0002912)1.84217057
106Focal seizures (HP:0007359)1.82812422
107Poor speech (HP:0002465)1.82672972
108CNS demyelination (HP:0007305)1.82232605
109Retinitis pigmentosa (HP:0000510)1.82070892
110Recurrent gram-negative bacterial infections (HP:0005420)1.81383692
111Epidermoid cyst (HP:0200040)1.81287615
112Hypophosphatemic rickets (HP:0004912)1.81024178
113Truncal ataxia (HP:0002078)1.80949503
114Left ventricular hypertrophy (HP:0001712)1.80868125
115Intention tremor (HP:0002080)1.80156260
116Anomalous pulmonary venous return (HP:0010772)1.79501064
117Abnormality of urine glucose concentration (HP:0011016)1.79439884
118Glycosuria (HP:0003076)1.79439884
119Deep venous thrombosis (HP:0002625)1.79429272
120Xanthomatosis (HP:0000991)1.79401149
121Double outlet right ventricle (HP:0001719)1.79399935
122Congenital malformation of the right heart (HP:0011723)1.79399935
123Vacuolated lymphocytes (HP:0001922)1.79283448
124Focal dystonia (HP:0004373)1.79175333
125Insidious onset (HP:0003587)1.78691301
126Termporal pattern (HP:0011008)1.78691301
127Abnormality of the diencephalon (HP:0010662)1.78033475
128Dysdiadochokinesis (HP:0002075)1.77641195
129Abnormal ciliary motility (HP:0012262)1.77404023
130Lethargy (HP:0001254)1.77029828
131Maternal diabetes (HP:0009800)1.76108278
132Irritability (HP:0000737)1.76064281
133Scanning speech (HP:0002168)1.75494608
134Infantile muscular hypotonia (HP:0008947)1.75459151
135Abnormal drinking behavior (HP:0030082)1.74728915
136Polydipsia (HP:0001959)1.74728915
137Split foot (HP:0001839)1.74217408
138Genital tract atresia (HP:0001827)1.73187752
139Medial flaring of the eyebrow (HP:0010747)1.72497170
140Poor coordination (HP:0002370)1.72420533
141Hip dysplasia (HP:0001385)1.72009601
142Anxiety (HP:0000739)1.71870935
143Adrenal hypoplasia (HP:0000835)1.71488861
144Generalized aminoaciduria (HP:0002909)1.71465480
145Turricephaly (HP:0000262)1.71344855
146Potter facies (HP:0002009)1.70519455
147Facial shape deformation (HP:0011334)1.70519455
148Abnormality of serine family amino acid metabolism (HP:0010894)1.70466105
149Abnormality of glycine metabolism (HP:0010895)1.70466105
150Amblyopia (HP:0000646)1.69958137
151Hypothermia (HP:0002045)1.69815113
152Generalized tonic-clonic seizures (HP:0002069)1.69640208
153Vaginal atresia (HP:0000148)1.69204483
154Abnormal respiratory motile cilium physiology (HP:0012261)1.68998864
155Epileptiform EEG discharges (HP:0011182)1.68992146
156Abnormality of methionine metabolism (HP:0010901)1.68846341
157Specific learning disability (HP:0001328)1.67992210
158Anophthalmia (HP:0000528)1.67912764
159Spastic gait (HP:0002064)1.67627890
160Lactic acidosis (HP:0003128)1.67427346
161Congenital ichthyosiform erythroderma (HP:0007431)1.67321530
162Synostosis involving the elbow (HP:0003938)1.65854070
163Humeroradial synostosis (HP:0003041)1.65854070
164EEG with generalized epileptiform discharges (HP:0011198)1.65732245
165Aplasia of the phalanges of the hand (HP:0009802)1.65520494
166Aplasia involving bones of the extremities (HP:0009825)1.65520494

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.96550209
2CASK3.45444007
3EPHB23.12055391
4OXSR12.91562886
5EPHA42.59444274
6BCR2.47542186
7WNK42.36764355
8NME12.31252756
9MAP3K112.22247635
10PBK2.03324051
11PRPF4B2.02721609
12NTRK32.02569051
13TNIK2.02259893
14PKN12.00796314
15WNK31.76254065
16MAP2K71.71628015
17PNCK1.68156868
18PLK21.65256983
19DYRK1B1.63310659
20UHMK11.56296717
21ARAF1.55773544
22CAMK2B1.54126879
23ABL21.53806412
24MAPKAPK51.49507036
25FGR1.46231395
26PRKCH1.41954878
27EPHA31.40716884
28LIMK11.37735209
29NTRK11.36546743
30CSNK1G31.33152697
31GRK51.30314278
32CAMK11.28585094
33MARK11.26907934
34WNK11.26245246
35CAMK2A1.26238067
36MAP3K41.26044356
37NEK61.24223285
38SGK4941.24212897
39SGK2231.24212897
40PIM21.20880395
41BMPR21.20143205
42CAMK2D1.19650872
43PTK2B1.17783135
44MAPK131.15374386
45CAMK2G1.15007005
46ROCK21.15006662
47ERBB41.12714200
48PAK31.12687216
49MET1.11236405
50NTRK21.11165903
51IRAK21.10823179
52DDR21.10583128
53OBSCN1.08962281
54PRKCE1.05409558
55CSNK1G21.04612364
56CSNK1A1L1.04476812
57CDK191.02268531
58ACVR1B1.02143454
59LRRK21.02009286
60PAK61.01522578
61MARK21.00124222
62BMPR1B0.99450487
63PRKCG0.97069011
64CSNK1G10.96788029
65MYLK0.96714403
66EPHB10.96123452
67FGFR20.96105142
68ADRBK20.95956975
69MINK10.94096957
70STK38L0.93678827
71PHKG10.91691094
72PHKG20.91691094
73CDK50.91115839
74DYRK30.91031678
75STK110.90289633
76STK160.86047975
77GRK10.86030442
78PRKD30.85137519
79DAPK30.83821415
80MAP3K120.83137840
81CDK140.82803580
82BRAF0.82556736
83DYRK1A0.82552337
84ERN10.76585430
85DYRK20.74599860
86PRKD20.72923274
87INSRR0.72828550
88KSR10.72596366
89AKT30.71591941
90CAMK1D0.71394909
91TIE10.70374379
92SIK20.69754657
93CDK180.69711541
94MAP2K40.67951799
95TAOK10.67638904
96CDK150.67577653
97RIPK10.67328812
98MUSK0.67263642
99GRK70.64794967
100MAP3K90.61825729
101MST40.61447533
102LATS20.60736629
103NME20.58326487
104BCKDK0.58087806
105RPS6KA20.57734353
106PRKG10.57694633
107PRKD10.57414264
108CDK11A0.57192548
109PRKCQ0.56801957
110KSR20.56548093
111MAPK150.56492169
112PRKACA0.56298634
113PRKACG0.56144381
114ADRBK10.56038424
115LMTK20.54519798
116NUAK10.53742621
117SGK30.53192321
118MAP3K20.53037541
119MOS0.52045916
120CAMK1G0.51674705
121DAPK20.51657283
122PDK20.50012928
123PINK10.49485698
124PRKACB0.49235303
125MAP2K60.48520075
126PRKCA0.48476321
127ERBB20.48166909
128PRKCD0.47773598
129PRKCZ0.47024033
130CSNK1A10.46900118
131PIK3CG0.45495721
132MAP3K130.43892856
133MATK0.43860956
134SGK10.41625083
135ROCK10.41533045
136PIK3CA0.40356662
137FES0.39690954
138FYN0.39342619
139TYRO30.36699945

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.37424101
2Steroid biosynthesis_Homo sapiens_hsa001003.15796138
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.06487598
4Fatty acid elongation_Homo sapiens_hsa000622.98812133
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.88309686
6Parkinsons disease_Homo sapiens_hsa050122.52423985
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.49871074
8Butanoate metabolism_Homo sapiens_hsa006502.25657138
9Alzheimers disease_Homo sapiens_hsa050102.19963870
10Sulfur metabolism_Homo sapiens_hsa009202.17188537
11Ribosome_Homo sapiens_hsa030101.95545851
12Collecting duct acid secretion_Homo sapiens_hsa049661.85876791
13Nicotine addiction_Homo sapiens_hsa050331.85015385
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.75780345
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.73689856
16Sulfur relay system_Homo sapiens_hsa041221.72050473
17Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.70715200
18Primary bile acid biosynthesis_Homo sapiens_hsa001201.67225015
19Cyanoamino acid metabolism_Homo sapiens_hsa004601.63691641
20Propanoate metabolism_Homo sapiens_hsa006401.62947839
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.61438903
22Caffeine metabolism_Homo sapiens_hsa002321.55963492
23Ether lipid metabolism_Homo sapiens_hsa005651.53678403
24Huntingtons disease_Homo sapiens_hsa050161.51051920
25Histidine metabolism_Homo sapiens_hsa003401.51021791
26GABAergic synapse_Homo sapiens_hsa047271.48850113
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46022553
28Cardiac muscle contraction_Homo sapiens_hsa042601.43974435
29Synaptic vesicle cycle_Homo sapiens_hsa047211.41477018
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.38645660
31Fatty acid metabolism_Homo sapiens_hsa012121.35117093
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.34122036
33Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.33201265
34Peroxisome_Homo sapiens_hsa041461.27079828
35Vibrio cholerae infection_Homo sapiens_hsa051101.26318969
36Glutamatergic synapse_Homo sapiens_hsa047241.23626931
37Pyruvate metabolism_Homo sapiens_hsa006201.21706758
38Protein export_Homo sapiens_hsa030601.21607308
39Vitamin B6 metabolism_Homo sapiens_hsa007501.20354791
40Serotonergic synapse_Homo sapiens_hsa047261.16121220
41Fatty acid degradation_Homo sapiens_hsa000711.15803202
42Tyrosine metabolism_Homo sapiens_hsa003501.11348719
43Starch and sucrose metabolism_Homo sapiens_hsa005001.10770990
44Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10110847
45Tryptophan metabolism_Homo sapiens_hsa003801.07524611
46Galactose metabolism_Homo sapiens_hsa000521.05994304
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.04279412
48Nitrogen metabolism_Homo sapiens_hsa009101.04129513
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.01692056
50Morphine addiction_Homo sapiens_hsa050320.98183000
51* Arginine and proline metabolism_Homo sapiens_hsa003300.97974699
52Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97748450
53Cocaine addiction_Homo sapiens_hsa050300.97685847
54Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.97647434
55Linoleic acid metabolism_Homo sapiens_hsa005910.96700015
56Amphetamine addiction_Homo sapiens_hsa050310.94660807
57Chemical carcinogenesis_Homo sapiens_hsa052040.93405429
58Phenylalanine metabolism_Homo sapiens_hsa003600.90722902
59Drug metabolism - other enzymes_Homo sapiens_hsa009830.89427966
60Circadian entrainment_Homo sapiens_hsa047130.87672567
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.87497860
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85994187
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.85102989
64Long-term depression_Homo sapiens_hsa047300.84888814
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84476929
66Sphingolipid metabolism_Homo sapiens_hsa006000.83436138
67Complement and coagulation cascades_Homo sapiens_hsa046100.83321811
68Axon guidance_Homo sapiens_hsa043600.82835169
69beta-Alanine metabolism_Homo sapiens_hsa004100.81576001
70Maturity onset diabetes of the young_Homo sapiens_hsa049500.77203247
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.76827321
72Dopaminergic synapse_Homo sapiens_hsa047280.75328258
73* Metabolic pathways_Homo sapiens_hsa011000.73745475
74Glycosaminoglycan degradation_Homo sapiens_hsa005310.72704631
75Staphylococcus aureus infection_Homo sapiens_hsa051500.71854579
76SNARE interactions in vesicular transport_Homo sapiens_hsa041300.71474360
77Arginine biosynthesis_Homo sapiens_hsa002200.70562703
78PPAR signaling pathway_Homo sapiens_hsa033200.69873494
79Taste transduction_Homo sapiens_hsa047420.68067662
80Insulin secretion_Homo sapiens_hsa049110.67898937
81Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66341867
82Other glycan degradation_Homo sapiens_hsa005110.62909133
83Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.60665618
84Salivary secretion_Homo sapiens_hsa049700.59867189
85Renin secretion_Homo sapiens_hsa049240.59532857
86Bile secretion_Homo sapiens_hsa049760.58918974
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58002332
88Folate biosynthesis_Homo sapiens_hsa007900.57455227
89Rheumatoid arthritis_Homo sapiens_hsa053230.56383863
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55719910
91Retinol metabolism_Homo sapiens_hsa008300.54612497
92Arachidonic acid metabolism_Homo sapiens_hsa005900.53484204
93Glutathione metabolism_Homo sapiens_hsa004800.53215675
94Lysosome_Homo sapiens_hsa041420.52790112
95Cholinergic synapse_Homo sapiens_hsa047250.52770131
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52561142
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.51115511
98Long-term potentiation_Homo sapiens_hsa047200.50667153
99Vitamin digestion and absorption_Homo sapiens_hsa049770.50647127
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.48466087
101Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46580331
102Fructose and mannose metabolism_Homo sapiens_hsa000510.45245545
103Glycerolipid metabolism_Homo sapiens_hsa005610.44801850
104Renin-angiotensin system_Homo sapiens_hsa046140.44716605
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.44333822
106Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.43696171
107Carbon metabolism_Homo sapiens_hsa012000.43527016
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43440345
109Protein digestion and absorption_Homo sapiens_hsa049740.42261258
110Mineral absorption_Homo sapiens_hsa049780.41418761
111Phagosome_Homo sapiens_hsa041450.40962490
112Regulation of autophagy_Homo sapiens_hsa041400.40862067
113Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38478654
114Phototransduction_Homo sapiens_hsa047440.37955405
115Gastric acid secretion_Homo sapiens_hsa049710.37396651
116Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36673358
117Fat digestion and absorption_Homo sapiens_hsa049750.36539939
118Calcium signaling pathway_Homo sapiens_hsa040200.36377850
119Prion diseases_Homo sapiens_hsa050200.35490131
120Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32467945
121Biosynthesis of amino acids_Homo sapiens_hsa012300.29207835

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