SATB2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.57658498
2vocalization behavior (GO:0071625)5.54075291
3synaptic vesicle docking involved in exocytosis (GO:0016081)5.53648282
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.46112757
5glutamate secretion (GO:0014047)5.41245617
6protein localization to synapse (GO:0035418)5.31592141
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.27361285
8synaptic vesicle exocytosis (GO:0016079)5.22695911
9regulation of short-term neuronal synaptic plasticity (GO:0048172)5.07126932
10positive regulation of potassium ion transmembrane transporter activity (GO:1901018)5.03486909
11axonal fasciculation (GO:0007413)5.01512436
12locomotory exploration behavior (GO:0035641)4.86143401
13presynaptic membrane assembly (GO:0097105)4.84015986
14membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.75933184
15neuron recognition (GO:0008038)4.75041793
16presynaptic membrane organization (GO:0097090)4.71491876
17synaptic vesicle maturation (GO:0016188)4.69643027
18positive regulation of synapse maturation (GO:0090129)4.67094948
19central nervous system projection neuron axonogenesis (GO:0021952)4.66375193
20regulation of synaptic vesicle exocytosis (GO:2000300)4.63186756
21postsynaptic membrane organization (GO:0001941)4.60270252
22layer formation in cerebral cortex (GO:0021819)4.57866284
23regulation of glutamate receptor signaling pathway (GO:1900449)4.57857439
24exploration behavior (GO:0035640)4.54646586
25positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.52995861
26myelination in peripheral nervous system (GO:0022011)4.44993065
27peripheral nervous system axon ensheathment (GO:0032292)4.44993065
28negative regulation of calcium ion-dependent exocytosis (GO:0045955)4.25759846
29dendritic spine morphogenesis (GO:0060997)4.17575908
30cell migration in hindbrain (GO:0021535)4.11024208
31regulation of axon extension involved in axon guidance (GO:0048841)4.09442083
32atrial cardiac muscle cell action potential (GO:0086014)4.09227798
33neurotransmitter-gated ion channel clustering (GO:0072578)4.06217225
34regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.01448451
35cellular response to nerve growth factor stimulus (GO:1990090)3.99230502
36response to nerve growth factor (GO:1990089)3.99230502
37cerebellar granule cell differentiation (GO:0021707)3.98730457
38ionotropic glutamate receptor signaling pathway (GO:0035235)3.93944617
39pyrimidine nucleobase catabolic process (GO:0006208)3.92939704
40regulation of long-term neuronal synaptic plasticity (GO:0048169)3.91631245
41regulation of axon guidance (GO:1902667)3.91277168
42cerebral cortex radially oriented cell migration (GO:0021799)3.84192718
43regulation of synaptic vesicle transport (GO:1902803)3.83194036
44limb bud formation (GO:0060174)3.82889643
45cerebral cortex cell migration (GO:0021795)3.82643305
46glutamate receptor signaling pathway (GO:0007215)3.82625885
47dendrite morphogenesis (GO:0048813)3.77727628
48synaptic transmission, glutamatergic (GO:0035249)3.76833960
49positive regulation of neurotransmitter secretion (GO:0001956)3.74427770
50regulation of dendritic spine morphogenesis (GO:0061001)3.73906728
51central nervous system neuron axonogenesis (GO:0021955)3.67747059
52positive regulation of dendrite morphogenesis (GO:0050775)3.63869545
53regulation of neuronal synaptic plasticity (GO:0048168)3.60665550
54regulation of excitatory postsynaptic membrane potential (GO:0060079)3.56044660
55regulation of synapse maturation (GO:0090128)3.54075030
56neuron-neuron synaptic transmission (GO:0007270)3.54004885
57short-term memory (GO:0007614)3.51002250
58regulation of dendritic spine development (GO:0060998)3.50987440
59regulation of postsynaptic membrane potential (GO:0060078)3.44211432
60proline transport (GO:0015824)3.42741860
61nucleobase catabolic process (GO:0046113)3.42394409
62regulation of heat generation (GO:0031650)3.40501345
63sympathetic nervous system development (GO:0048485)3.40378671
64positive regulation of membrane potential (GO:0045838)3.40007457
65regulation of sarcomere organization (GO:0060297)3.39814185
66astrocyte development (GO:0014002)3.38265765
67synaptic vesicle endocytosis (GO:0048488)3.36809731
68positive regulation of potassium ion transmembrane transport (GO:1901381)3.33787736
69establishment of mitochondrion localization (GO:0051654)3.33716575
70regulation of synaptic plasticity (GO:0048167)3.33496236
71regulation of neurotransmitter secretion (GO:0046928)3.33070125
72cell morphogenesis involved in neuron differentiation (GO:0048667)3.33024621
73neuronal action potential propagation (GO:0019227)3.30829804
74regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.30643360
75neurotransmitter secretion (GO:0007269)3.30560816
76positive regulation of cardiac muscle hypertrophy (GO:0010613)3.29192765
77positive regulation of muscle hypertrophy (GO:0014742)3.29192765
78regulation of synapse structural plasticity (GO:0051823)3.26462043
79mitochondrion transport along microtubule (GO:0047497)3.26045896
80establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.26045896
81long-term synaptic potentiation (GO:0060291)3.25360965
82protein localization to endosome (GO:0036010)3.25308976
83positive regulation of potassium ion transport (GO:0043268)3.21424290
84negative regulation of synaptic transmission, GABAergic (GO:0032229)3.19335196
85gamma-aminobutyric acid signaling pathway (GO:0007214)3.14880709
86dendritic spine organization (GO:0097061)3.14848170
87membrane depolarization during action potential (GO:0086010)3.14095310
88axon extension (GO:0048675)3.11662084
89positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.09156926
90ephrin receptor signaling pathway (GO:0048013)3.06773085
91cochlea development (GO:0090102)3.06684953
92G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06568674
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.06325122
94positive regulation of synapse assembly (GO:0051965)3.06124421
95epithelial cell differentiation involved in kidney development (GO:0035850)3.03559153
96long-term memory (GO:0007616)3.02307015
97establishment of nucleus localization (GO:0040023)2.99938186
98cardiac ventricle formation (GO:0003211)2.99516330
99regulation of synapse assembly (GO:0051963)2.98381198
100auditory behavior (GO:0031223)2.97305748
101positive regulation of dendrite development (GO:1900006)2.94468186
102neuron projection extension (GO:1990138)2.94366419
103positive regulation of dendritic spine morphogenesis (GO:0061003)2.93933060
104anatomical structure arrangement (GO:0048532)2.93460091
105dendrite development (GO:0016358)2.92644733
106regulation of synapse organization (GO:0050807)2.91470971
107C4-dicarboxylate transport (GO:0015740)2.90747336
108synapse assembly (GO:0007416)2.90467138
109regulation of cardiac muscle cell contraction (GO:0086004)2.90422928
110cranial nerve morphogenesis (GO:0021602)2.90210183
111organelle transport along microtubule (GO:0072384)2.90065425
112regulation of synaptic transmission, glutamatergic (GO:0051966)2.89359180
113behavioral defense response (GO:0002209)2.88439707
114behavioral fear response (GO:0001662)2.88439707
115membrane assembly (GO:0071709)2.87832253
116response to histamine (GO:0034776)2.87631731
117regulation of vesicle fusion (GO:0031338)2.87106078
118positive regulation of dendritic spine development (GO:0060999)2.86722143
119positive regulation of neurotransmitter transport (GO:0051590)2.85699845
120gamma-aminobutyric acid transport (GO:0015812)2.84147521
121cranial nerve structural organization (GO:0021604)2.82969411
122facial nerve structural organization (GO:0021612)2.80580031
123regulation of neurotransmitter transport (GO:0051588)2.80500051
124response to pheromone (GO:0019236)2.80354786
125fear response (GO:0042596)2.79830633
126mechanosensory behavior (GO:0007638)2.79782641
127negative regulation of neurotransmitter transport (GO:0051589)2.77162024
128positive regulation of cardiac muscle cell differentiation (GO:2000727)2.77046197
129synapse organization (GO:0050808)2.76291371
130regulation of dendrite development (GO:0050773)2.74880094
131negative regulation of axonogenesis (GO:0050771)2.74707987
132positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.74457822
133innervation (GO:0060384)2.73853744
134learning (GO:0007612)2.72855024
135telencephalon cell migration (GO:0022029)2.71050202
136regulation of dendrite morphogenesis (GO:0048814)2.70800125
137neurotransmitter transport (GO:0006836)2.70753235
138cell communication involved in cardiac conduction (GO:0086065)2.70585743
139cardiac chamber formation (GO:0003207)2.70497440
140startle response (GO:0001964)2.67915444
141mitochondrial genome maintenance (GO:0000002)2.67693677
142sodium ion export (GO:0071436)2.67563423
143negative regulation of dendrite development (GO:2000171)2.67401702
144G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.66107406
145regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.64118057
146regulation of NFAT protein import into nucleus (GO:0051532)2.63545028
147forebrain cell migration (GO:0021885)2.63353894
148membrane depolarization (GO:0051899)2.62122145
149regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.61727109
150negative regulation of nucleotide biosynthetic process (GO:0030809)2.61315021

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.09749417
2GBX2_23144817_ChIP-Seq_PC3_Human3.77267415
3* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.95667985
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95170502
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.81371742
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.67617470
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.65996011
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.58461390
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.58461390
10* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.48801039
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.46371518
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.44914590
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.41915263
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36719723
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.35927591
16RNF2_27304074_Chip-Seq_ESCs_Mouse2.20228653
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.18997927
18AR_21572438_ChIP-Seq_LNCaP_Human2.17778564
19* REST_21632747_ChIP-Seq_MESCs_Mouse2.17384517
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.14915844
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11957369
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.06612815
23DROSHA_22980978_ChIP-Seq_HELA_Human2.03703403
24* EZH2_27294783_Chip-Seq_ESCs_Mouse1.99712506
25* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.98200014
26ZFP57_27257070_Chip-Seq_ESCs_Mouse1.94150789
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.92651454
28* SALL1_21062744_ChIP-ChIP_HESCs_Human1.84865779
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.84757935
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81234448
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.78454188
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.77187104
33MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.75567747
34TAF15_26573619_Chip-Seq_HEK293_Human1.75026627
35TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.72857315
36FUS_26573619_Chip-Seq_HEK293_Human1.65984746
37* CBX2_27304074_Chip-Seq_ESCs_Mouse1.65101556
38* REST_18959480_ChIP-ChIP_MESCs_Mouse1.64338970
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.62136970
40PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.61271309
41* SMAD4_21799915_ChIP-Seq_A2780_Human1.60528087
42* P300_19829295_ChIP-Seq_ESCs_Human1.59577246
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57965374
44* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56401600
45EWS_26573619_Chip-Seq_HEK293_Human1.56186945
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.53715896
47* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52427143
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51488616
49EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45608559
50ZNF274_21170338_ChIP-Seq_K562_Hela1.44358507
51CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.43994830
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42937245
53* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.42032146
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41316595
55LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39316149
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.37899564
57RNF2_27304074_Chip-Seq_NSC_Mouse1.37714783
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34866136
59SOX2_21211035_ChIP-Seq_LN229_Gbm1.33293874
60ARNT_22903824_ChIP-Seq_MCF-7_Human1.32809083
61CBP_20019798_ChIP-Seq_JUKART_Human1.32800563
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32800563
63SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32796676
64* FLI1_27457419_Chip-Seq_LIVER_Mouse1.32399213
65* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32306707
66P53_22127205_ChIP-Seq_FIBROBLAST_Human1.28931219
67* RING1B_27294783_Chip-Seq_NPCs_Mouse1.28353245
68ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28253969
69NRF2_20460467_ChIP-Seq_MEFs_Mouse1.28207305
70NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.28207305
71AR_25329375_ChIP-Seq_VCAP_Human1.27582821
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26459600
73ERG_21242973_ChIP-ChIP_JURKAT_Human1.26158751
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25565750
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25462321
76* RING1B_27294783_Chip-Seq_ESCs_Mouse1.24225602
77CTNNB1_20460455_ChIP-Seq_HCT116_Human1.23712564
78TP53_16413492_ChIP-PET_HCT116_Human1.23495767
79* SOX9_26525672_Chip-Seq_HEART_Mouse1.22304997
80* STAT3_23295773_ChIP-Seq_U87_Human1.22043428
81BCAT_22108803_ChIP-Seq_LS180_Human1.20513615
82NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20201043
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19856019
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19856019
85AHR_22903824_ChIP-Seq_MCF-7_Human1.18867221
86TP53_18474530_ChIP-ChIP_U2OS_Human1.18617918
87* AR_19668381_ChIP-Seq_PC3_Human1.16077652
88IGF1R_20145208_ChIP-Seq_DFB_Human1.15600812
89KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14693935
90TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14435635
91* CMYC_18555785_Chip-Seq_ESCs_Mouse1.14150083
92* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13662578
93YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13492063
94NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13109356
95* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.11223401
96KDM2B_26808549_Chip-Seq_REH_Human1.11078958
97* TCF4_23295773_ChIP-Seq_U87_Human1.10941311
98IKZF1_21737484_ChIP-ChIP_HCT116_Human1.10762019
99* P53_22387025_ChIP-Seq_ESCs_Mouse1.10547338
100TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09581917
101CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.09178737
102TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08858932
103WT1_25993318_ChIP-Seq_PODOCYTE_Human1.07776873
104PRDM14_20953172_ChIP-Seq_ESCs_Human1.07513312
105TCF4_22108803_ChIP-Seq_LS180_Human1.07012409
106RXR_22108803_ChIP-Seq_LS180_Human1.05781321
107UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02910999
108* NANOG_18555785_Chip-Seq_ESCs_Mouse1.02673797
109ER_23166858_ChIP-Seq_MCF-7_Human1.02547622
110* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01773615
111RUNX2_22187159_ChIP-Seq_PCA_Human1.01555060
112SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01141463
113VDR_22108803_ChIP-Seq_LS180_Human1.01138203
114JUN_21703547_ChIP-Seq_K562_Human1.00340920
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99244345
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96854221
117VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96596862
118SMAD3_21741376_ChIP-Seq_HESCs_Human0.95694707
119SMAD3_21741376_ChIP-Seq_ESCs_Human0.93693435
120* TCF4_18268006_ChIP-ChIP_LS174T_Human0.93568741
121* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93517837

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.14878230
2MP0003880_abnormal_central_pattern4.74808968
3MP0004270_analgesia4.07802415
4MP0003635_abnormal_synaptic_transmissio3.67921358
5MP0002063_abnormal_learning/memory/cond3.18313229
6MP0004043_abnormal_pH_regulation3.15030523
7MP0000778_abnormal_nervous_system3.02684703
8MP0001968_abnormal_touch/_nociception2.76160466
9MP0009745_abnormal_behavioral_response2.75836723
10MP0002734_abnormal_mechanical_nocicepti2.66326664
11MP0009780_abnormal_chondrocyte_physiolo2.66227675
12MP0002064_seizures2.61688750
13MP0002572_abnormal_emotion/affect_behav2.61189131
14MP0009046_muscle_twitch2.44673156
15MP0001486_abnormal_startle_reflex2.36620152
16MP0005423_abnormal_somatic_nervous2.29678286
17MP0002736_abnormal_nociception_after2.24140544
18MP0001440_abnormal_grooming_behavior2.14051715
19MP0002735_abnormal_chemical_nociception2.06241801
20MP0002272_abnormal_nervous_system1.80948025
21MP0002184_abnormal_innervation1.74103068
22MP0002733_abnormal_thermal_nociception1.71368325
23MP0001970_abnormal_pain_threshold1.70017884
24MP0003329_amyloid_beta_deposits1.69252419
25MP0002067_abnormal_sensory_capabilities1.66757527
26MP0005386_behavior/neurological_phenoty1.65399405
27MP0004924_abnormal_behavior1.65399405
28MP0004811_abnormal_neuron_physiology1.64768205
29MP0000569_abnormal_digit_pigmentation1.62853752
30MP0004885_abnormal_endolymph1.62592407
31MP0000955_abnormal_spinal_cord1.61008028
32MP0002751_abnormal_autonomic_nervous1.60253021
33MP0004858_abnormal_nervous_system1.57368275
34MP0003879_abnormal_hair_cell1.56097165
35MP0002557_abnormal_social/conspecific_i1.53383840
36MP0003868_abnormal_feces_composition1.53238554
37MP0001501_abnormal_sleep_pattern1.49950536
38MP0003787_abnormal_imprinting1.42332890
39MP0002882_abnormal_neuron_morphology1.42078138
40MP0001188_hyperpigmentation1.40408228
41MP0003938_abnormal_ear_development1.38511781
42MP0008872_abnormal_physiological_respon1.37323017
43MP0003122_maternal_imprinting1.35801519
44MP0009384_cardiac_valve_regurgitation1.32484805
45MP0002152_abnormal_brain_morphology1.31316058
46MP0002066_abnormal_motor_capabilities/c1.28822868
47MP0004134_abnormal_chest_morphology1.27290023
48MP0005187_abnormal_penis_morphology1.24436269
49MP0008569_lethality_at_weaning1.21386140
50MP0000631_abnormal_neuroendocrine_gland1.15137055
51MP0001984_abnormal_olfaction1.13180435
52MP0009250_abnormal_appendicular_skeleto1.11653296
53MP0003861_abnormal_nervous_system1.10514291
54MP0005171_absent_coat_pigmentation1.10089681
55MP0003633_abnormal_nervous_system1.08096674
56MP0000049_abnormal_middle_ear1.06070223
57MP0005551_abnormal_eye_electrophysiolog1.05605036
58MP0003283_abnormal_digestive_organ1.03814071
59MP0004742_abnormal_vestibular_system1.02729958
60MP0003385_abnormal_body_wall1.01731430
61MP0000537_abnormal_urethra_morphology1.01270998
62MP0003119_abnormal_digestive_system1.00384215
63MP0003631_nervous_system_phenotype0.99144662
64MP0002102_abnormal_ear_morphology0.98790856
65MP0004484_altered_response_of0.97688906
66* MP0003755_abnormal_palate_morphology0.97516722
67MP0006276_abnormal_autonomic_nervous0.96571268
68MP0001963_abnormal_hearing_physiology0.95414490
69MP0001905_abnormal_dopamine_level0.94831845
70MP0004147_increased_porphyrin_level0.94134695
71MP0010352_gastrointestinal_tract_polyps0.93811266
72MP0005646_abnormal_pituitary_gland0.91704514
73MP0000534_abnormal_ureter_morphology0.90714063
74MP0003937_abnormal_limbs/digits/tail_de0.89460138
75MP0006292_abnormal_olfactory_placode0.88672998
76MP0005623_abnormal_meninges_morphology0.87668329
77MP0000462_abnormal_digestive_system0.87558213
78MP0002653_abnormal_ependyma_morphology0.86642350
79MP0000427_abnormal_hair_cycle0.86484294
80* MP0002116_abnormal_craniofacial_bone0.85393079
81MP0002234_abnormal_pharynx_morphology0.84732033
82MP0002822_catalepsy0.84440017
83MP0004233_abnormal_muscle_weight0.82683727
84MP0005174_abnormal_tail_pigmentation0.81507039
85MP0000026_abnormal_inner_ear0.80967434
86MP0001299_abnormal_eye_distance/0.78963945
87MP0002876_abnormal_thyroid_physiology0.78308880
88MP0005394_taste/olfaction_phenotype0.78307814
89MP0005499_abnormal_olfactory_system0.78307814
90* MP0002896_abnormal_bone_mineralization0.76375502
91MP0002752_abnormal_somatic_nervous0.75924545
92MP0002069_abnormal_eating/drinking_beha0.74736089
93MP0003121_genomic_imprinting0.74639364
94MP0000516_abnormal_urinary_system0.74586784
95MP0005367_renal/urinary_system_phenotyp0.74586784
96* MP0002082_postnatal_lethality0.74522572
97* MP0010770_preweaning_lethality0.74522572
98* MP0003935_abnormal_craniofacial_develop0.74106531
99MP0001485_abnormal_pinna_reflex0.73814740
100MP0003045_fibrosis0.73504786
101MP0004145_abnormal_muscle_electrophysio0.73156479
102MP0001502_abnormal_circadian_rhythm0.73095348
103MP0004085_abnormal_heartbeat0.73020147
104MP0003137_abnormal_impulse_conducting0.72043472
105* MP0010769_abnormal_survival0.71678151
106MP0002909_abnormal_adrenal_gland0.71573646
107MP0001177_atelectasis0.71373917
108MP0001529_abnormal_vocalization0.71133826
109MP0003632_abnormal_nervous_system0.70779696
110MP0005645_abnormal_hypothalamus_physiol0.70536621
111* MP0002233_abnormal_nose_morphology0.70233413
112MP0001943_abnormal_respiration0.69955313
113MP0000647_abnormal_sebaceous_gland0.69440166
114* MP0002081_perinatal_lethality0.69370271
115MP0001664_abnormal_digestion0.69294104
116MP0000538_abnormal_urinary_bladder0.68652580
117* MP0000762_abnormal_tongue_morphology0.68502500
118* MP0010768_mortality/aging0.68480028
119MP0005670_abnormal_white_adipose0.67864745
120MP0000920_abnormal_myelination0.67802399
121MP0003634_abnormal_glial_cell0.66196922
122MP0008789_abnormal_olfactory_epithelium0.65952938
123MP0002168_other_aberrant_phenotype0.65680863
124MP0003942_abnormal_urinary_system0.65526840
125MP0005503_abnormal_tendon_morphology0.65347077
126MP0002971_abnormal_brown_adipose0.65223721
127MP0002229_neurodegeneration0.61349572

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.71065377
2Epileptic encephalopathy (HP:0200134)5.26252638
3Hyperventilation (HP:0002883)5.10163057
4Focal seizures (HP:0007359)4.54194717
5Myokymia (HP:0002411)4.42743769
6Visual hallucinations (HP:0002367)3.70970696
7Atonic seizures (HP:0010819)3.63353864
8* Broad-based gait (HP:0002136)3.44605416
9Excessive salivation (HP:0003781)3.43133335
10Drooling (HP:0002307)3.43133335
11Amblyopia (HP:0000646)3.16282457
12Genetic anticipation (HP:0003743)3.14363187
13Febrile seizures (HP:0002373)3.13163142
14Progressive cerebellar ataxia (HP:0002073)3.09074201
15Poor eye contact (HP:0000817)3.06061631
16Obstructive sleep apnea (HP:0002870)3.04167126
17Neoplasm of the oral cavity (HP:0100649)2.95710872
18Abnormality of the corticospinal tract (HP:0002492)2.95081656
19Termporal pattern (HP:0011008)2.91727858
20Insidious onset (HP:0003587)2.91727858
21Cerebral inclusion bodies (HP:0100314)2.89389108
22Absence seizures (HP:0002121)2.87232916
23Short chin (HP:0000331)2.85740500
24Absent speech (HP:0001344)2.82548089
25Mutism (HP:0002300)2.78482802
26Dialeptic seizures (HP:0011146)2.77493290
27Impaired social interactions (HP:0000735)2.74565506
28Abnormal social behavior (HP:0012433)2.74565506
29Hepatoblastoma (HP:0002884)2.71954310
30Urinary bladder sphincter dysfunction (HP:0002839)2.70753425
31Supranuclear gaze palsy (HP:0000605)2.61671450
32Submucous cleft hard palate (HP:0000176)2.59399040
33Generalized tonic-clonic seizures (HP:0002069)2.58072170
34Amyotrophic lateral sclerosis (HP:0007354)2.57523818
35Inability to walk (HP:0002540)2.55641011
36Inappropriate behavior (HP:0000719)2.54523402
37Neurofibrillary tangles (HP:0002185)2.49796881
38Heterotopia (HP:0002282)2.49073403
39Epileptiform EEG discharges (HP:0011182)2.43746290
40Stereotypic behavior (HP:0000733)2.43474135
41Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.38922741
42Short 4th metacarpal (HP:0010044)2.38922741
43Midline defect of the nose (HP:0004122)2.38707550
44Gaze-evoked nystagmus (HP:0000640)2.35365694
45Progressive inability to walk (HP:0002505)2.34841554
46Microglossia (HP:0000171)2.34424928
47Action tremor (HP:0002345)2.32867535
48Shallow orbits (HP:0000586)2.31974324
49Akinesia (HP:0002304)2.31318298
50Urinary urgency (HP:0000012)2.27020878
51Protruding tongue (HP:0010808)2.26273772
52Ankle clonus (HP:0011448)2.26206625
53Abnormality of salivation (HP:0100755)2.26084337
54Lissencephaly (HP:0001339)2.25764698
55Large earlobe (HP:0009748)2.24331709
56Abnormal eating behavior (HP:0100738)2.23326233
57Fetal akinesia sequence (HP:0001989)2.22420093
58EEG with generalized epileptiform discharges (HP:0011198)2.22251778
59Glioma (HP:0009733)2.18319596
60Tented upper lip vermilion (HP:0010804)2.15777081
61Meningioma (HP:0002858)2.14950153
62Papilledema (HP:0001085)2.14637081
63Cupped ear (HP:0000378)2.13586274
64Degeneration of the lateral corticospinal tracts (HP:0002314)2.13463217
65Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.13463217
66Polyphagia (HP:0002591)2.13148044
67Abnormality of the labia minora (HP:0012880)2.11139307
68Impaired vibration sensation in the lower limbs (HP:0002166)2.10539144
69Hypsarrhythmia (HP:0002521)2.10167391
70Diplopia (HP:0000651)2.09486277
71Abnormality of binocular vision (HP:0011514)2.09486277
72Dysmetria (HP:0001310)2.08975701
73Abnormality of ocular smooth pursuit (HP:0000617)2.06158258
74Bifid tongue (HP:0010297)2.05773717
75Exotropia (HP:0000577)2.03434944
76Relative macrocephaly (HP:0004482)2.03226205
77Cutaneous finger syndactyly (HP:0010554)1.99200177
78Gastroesophageal reflux (HP:0002020)1.97988668
79Neoplasm of the adrenal cortex (HP:0100641)1.97817198
80Hemiparesis (HP:0001269)1.97531543
81Abnormality of the intrinsic pathway (HP:0010989)1.97275351
82Megalencephaly (HP:0001355)1.97038167
83Prolonged QT interval (HP:0001657)1.95858834
84Limb dystonia (HP:0002451)1.95289506
85Thickened helices (HP:0000391)1.95259311
86Spastic gait (HP:0002064)1.92105302
87Blue irides (HP:0000635)1.91248508
88Syncope (HP:0001279)1.91022900
89Aqueductal stenosis (HP:0002410)1.90751928
90Epidermoid cyst (HP:0200040)1.90600512
91Metabolic alkalosis (HP:0200114)1.89384931
92Open mouth (HP:0000194)1.88367721
93Impaired smooth pursuit (HP:0007772)1.88006349
94Volvulus (HP:0002580)1.87961065
95Sleep apnea (HP:0010535)1.87403652
96Widely spaced teeth (HP:0000687)1.86785422
97Hyperthyroidism (HP:0000836)1.85755546
98Pheochromocytoma (HP:0002666)1.84179653
99Fair hair (HP:0002286)1.81009263
100Abnormality of the astrocytes (HP:0100707)1.79860201
101Astrocytoma (HP:0009592)1.79860201
102Intellectual disability, progressive (HP:0006887)1.78465632
103Generalized myoclonic seizures (HP:0002123)1.77898609
104Dysdiadochokinesis (HP:0002075)1.77203646
105Buphthalmos (HP:0000557)1.76694362
106Torticollis (HP:0000473)1.75857162
107Truncal ataxia (HP:0002078)1.74202605
108Facial hemangioma (HP:0000329)1.73087144
109Apathy (HP:0000741)1.72408691
110Type II lissencephaly (HP:0007260)1.72078808
111Abnormal EKG (HP:0003115)1.71157332
112Impaired vibratory sensation (HP:0002495)1.70551106
113Lower limb muscle weakness (HP:0007340)1.70438214
114Polymicrogyria (HP:0002126)1.68346100
115Partial agenesis of the corpus callosum (HP:0001338)1.68302815
116Intellectual disability, severe (HP:0010864)1.68010212
117Tracheomalacia (HP:0002779)1.67774347
118Hydroureter (HP:0000072)1.67604997
119Short philtrum (HP:0000322)1.65977235
120Heterochromia iridis (HP:0001100)1.64885599
121Renal cortical cysts (HP:0000803)1.64727116
122Colon cancer (HP:0003003)1.64650445
123Lower limb amyotrophy (HP:0007210)1.64294867
124Patellar aplasia (HP:0006443)1.63332177
125Abnormality of the lower motor neuron (HP:0002366)1.62729933
126Overgrowth (HP:0001548)1.62613420
127Increased number of teeth (HP:0011069)1.61452949
128Depression (HP:0000716)1.60496645
129Benign neoplasm of the central nervous system (HP:0100835)1.60038424
130Gait imbalance (HP:0002141)1.58713195
131Generalized hypopigmentation of hair (HP:0011358)1.58544536
132Clumsiness (HP:0002312)1.58488401
133Hypoplasia of the corpus callosum (HP:0002079)1.58396995
134Arterial tortuosity (HP:0005116)1.58385479
135Muscular hypotonia of the trunk (HP:0008936)1.58169517
136Cutaneous syndactyly (HP:0012725)1.57618923
137Abnormality of the 4th metacarpal (HP:0010012)1.57492907
138Pachygyria (HP:0001302)1.57472779
139Hyperactive renin-angiotensin system (HP:0000841)1.57448936

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.32904067
2CASK4.17912152
3EPHA44.10114975
4FRK3.26845638
5MAP3K93.21620974
6NTRK32.87212973
7MAP3K42.85224134
8DAPK22.76933400
9MAP2K72.52735638
10PLK22.27115019
11CDK192.00992799
12MINK11.98085738
13CCNB11.96028331
14PAK61.89262343
15LATS21.88546733
16NUAK11.75861845
17DAPK11.73082162
18PNCK1.71530167
19KSR11.68822179
20MAPK131.62927931
21MAP2K41.54009994
22MAP3K121.51221942
23NTRK21.50985831
24OXSR11.44910277
25DYRK21.43945422
26AKT31.39526132
27PINK11.39290439
28EPHA31.36982273
29RIPK41.28262956
30CDK51.25959433
31CAMKK11.23509623
32PRPF4B1.19018338
33GRK51.18990432
34KSR21.15783255
35CDC42BPA1.11981140
36SIK21.08164791
37CSNK1G21.07346795
38PHKG11.07306122
39PHKG21.07306122
40NTRK11.06078521
41EPHB21.03912796
42TYRO31.03692548
43PDGFRA1.01772401
44TAOK11.01247101
45DDR21.01170919
46TGFBR20.99593430
47PRKCG0.99535184
48ACVR1B0.93152204
49FGR0.90861207
50CAMK2A0.89569928
51CAMK1D0.89384173
52CDK180.86748029
53PKN10.85435336
54CDK150.84509895
55DYRK1A0.84148893
56STK110.83495123
57MAP3K60.83149579
58EIF2AK30.80951926
59CDK140.80048133
60PRKD30.79018545
61ICK0.77324529
62MKNK20.76758215
63CAMK40.74873224
64PAK30.74213362
65CAMK2B0.73796466
66CAMKK20.73685285
67ERBB30.73415658
68PIK3CA0.73034191
69CDK11A0.72656175
70PTK2B0.72177376
71CDK30.71830503
72TNIK0.70700147
73ROCK10.69608466
74WNK10.68431256
75MARK20.67649998
76TAOK30.67562348
77MET0.64394736
78UHMK10.64255224
79SGK2230.63402804
80SGK4940.63402804
81LIMK10.61257050
82MAPK120.60994802
83SGK10.60036834
84CAMK1G0.55791632
85CSNK1A1L0.55139108
86RAF10.54537003
87PRKCE0.53839927
88BMPR20.52818172
89LMTK20.52639101
90STK380.52026575
91WNK30.52017524
92PRKCZ0.51421533
93MAP3K20.50347333
94ARAF0.50025936
95RET0.49313113
96DAPK30.49042501
97ILK0.48362733
98BCR0.48054379
99MST1R0.47018549
100PDGFRB0.46988620
101DMPK0.46701069
102CSNK1G30.45940122
103CAMK10.44841447
104FGFR20.44055637
105EIF2AK10.43631224
106ALK0.43559247
107SGK20.42482738
108PRKDC0.41455671
109CSNK1E0.41368161
110TRPM70.41196158
111MAPK70.41031957
112CSNK1G10.40485634
113PRKCI0.40159712
114PLK30.39169974
115TRIM280.38890229
116WNK40.38293768
117LATS10.37976838
118FYN0.37490816
119GSK3B0.37128288
120PDPK10.37013935
121STK390.36886544
122NME10.36143301
123ERBB20.35668729
124GRK10.34424764
125ROCK20.34056654
126PRKCB0.33499865
127BMPR1B0.33233224
128CSNK1A10.32061203
129CAMK2D0.31823575
130GRK60.30813109
131INSRR0.30802077
132SGK30.30005439
133ADRBK10.29843405
134RPS6KA30.29445321
135YES10.28488944

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.25285281
2Synaptic vesicle cycle_Homo sapiens_hsa047212.98018308
3Long-term potentiation_Homo sapiens_hsa047202.53000509
4Circadian entrainment_Homo sapiens_hsa047132.50241551
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.45350486
6Glutamatergic synapse_Homo sapiens_hsa047242.42484433
7Axon guidance_Homo sapiens_hsa043602.28856414
8Olfactory transduction_Homo sapiens_hsa047402.27401237
9Amphetamine addiction_Homo sapiens_hsa050312.18267761
10Morphine addiction_Homo sapiens_hsa050322.14358182
11Salivary secretion_Homo sapiens_hsa049702.11834480
12GABAergic synapse_Homo sapiens_hsa047272.09483574
13Dopaminergic synapse_Homo sapiens_hsa047282.05656778
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.88252443
15Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.84892316
16Renin secretion_Homo sapiens_hsa049241.84687258
17Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.82039393
18Nitrogen metabolism_Homo sapiens_hsa009101.74397246
19Cholinergic synapse_Homo sapiens_hsa047251.73586983
20Long-term depression_Homo sapiens_hsa047301.70978638
21Gastric acid secretion_Homo sapiens_hsa049711.70503222
22Oxytocin signaling pathway_Homo sapiens_hsa049211.63411247
23Serotonergic synapse_Homo sapiens_hsa047261.60991789
24Insulin secretion_Homo sapiens_hsa049111.60548235
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.57631038
26Taste transduction_Homo sapiens_hsa047421.53255488
27Gap junction_Homo sapiens_hsa045401.52940719
28Collecting duct acid secretion_Homo sapiens_hsa049661.51640606
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46451196
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38103055
31Calcium signaling pathway_Homo sapiens_hsa040201.36027270
32ErbB signaling pathway_Homo sapiens_hsa040121.35158945
33GnRH signaling pathway_Homo sapiens_hsa049121.34644657
34Glioma_Homo sapiens_hsa052141.27275012
35Melanogenesis_Homo sapiens_hsa049161.24069617
36Cocaine addiction_Homo sapiens_hsa050301.24002250
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22701110
38Estrogen signaling pathway_Homo sapiens_hsa049151.17272678
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15203211
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.14178276
41cAMP signaling pathway_Homo sapiens_hsa040241.13668172
42Vibrio cholerae infection_Homo sapiens_hsa051101.07687438
43Bile secretion_Homo sapiens_hsa049761.07682282
44Type II diabetes mellitus_Homo sapiens_hsa049301.05068915
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05016266
46Wnt signaling pathway_Homo sapiens_hsa043101.04216377
47Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.01805121
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.00145994
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00069534
50Colorectal cancer_Homo sapiens_hsa052100.99966951
51Oocyte meiosis_Homo sapiens_hsa041140.98318148
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93470993
53Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.92049436
54Butanoate metabolism_Homo sapiens_hsa006500.91763529
55Endometrial cancer_Homo sapiens_hsa052130.91755958
56Renal cell carcinoma_Homo sapiens_hsa052110.91009675
57Dorso-ventral axis formation_Homo sapiens_hsa043200.90922585
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.90603197
59Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87488720
60Hedgehog signaling pathway_Homo sapiens_hsa043400.87118447
61Choline metabolism in cancer_Homo sapiens_hsa052310.86806875
62Ras signaling pathway_Homo sapiens_hsa040140.83595715
63MAPK signaling pathway_Homo sapiens_hsa040100.82152330
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.80140649
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.79769699
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.79711964
67Phototransduction_Homo sapiens_hsa047440.79024473
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78590681
69Propanoate metabolism_Homo sapiens_hsa006400.76516357
70Hippo signaling pathway_Homo sapiens_hsa043900.76347000
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74696434
72Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73789803
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.73739224
74Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71989241
75Caffeine metabolism_Homo sapiens_hsa002320.71392620
76Rap1 signaling pathway_Homo sapiens_hsa040150.69312294
77Fatty acid biosynthesis_Homo sapiens_hsa000610.67955028
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.67366262
79Tight junction_Homo sapiens_hsa045300.67023456
80VEGF signaling pathway_Homo sapiens_hsa043700.66572181
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.65449691
82mTOR signaling pathway_Homo sapiens_hsa041500.64378760
83Basal cell carcinoma_Homo sapiens_hsa052170.63519107
84Glucagon signaling pathway_Homo sapiens_hsa049220.62518297
85Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61415593
86Dilated cardiomyopathy_Homo sapiens_hsa054140.60519833
87Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.59956485
88ABC transporters_Homo sapiens_hsa020100.59658664
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59393611
90Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59154315
91Pancreatic secretion_Homo sapiens_hsa049720.58936525
92Sphingolipid metabolism_Homo sapiens_hsa006000.58607506
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.58483902
94TGF-beta signaling pathway_Homo sapiens_hsa043500.56761574
95Cardiac muscle contraction_Homo sapiens_hsa042600.56113228
96Lysine degradation_Homo sapiens_hsa003100.55769577
97Circadian rhythm_Homo sapiens_hsa047100.55036330
98Inositol phosphate metabolism_Homo sapiens_hsa005620.53833584
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53185753
100Sulfur metabolism_Homo sapiens_hsa009200.52988583
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52247575
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.50178079
103Endocytosis_Homo sapiens_hsa041440.49876627
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49462291
105Mineral absorption_Homo sapiens_hsa049780.49397974
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48006051
107Prolactin signaling pathway_Homo sapiens_hsa049170.47866454
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47082396
109Adherens junction_Homo sapiens_hsa045200.46627674
110Glycerolipid metabolism_Homo sapiens_hsa005610.46164531
111Melanoma_Homo sapiens_hsa052180.45824940
112Thyroid hormone synthesis_Homo sapiens_hsa049180.45123977
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45093853
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44419683
115N-Glycan biosynthesis_Homo sapiens_hsa005100.43742256
116African trypanosomiasis_Homo sapiens_hsa051430.38664873
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38359997
118Non-small cell lung cancer_Homo sapiens_hsa052230.38219989
119Alcoholism_Homo sapiens_hsa050340.37760282
120Focal adhesion_Homo sapiens_hsa045100.34983465
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.34651583
122Insulin signaling pathway_Homo sapiens_hsa049100.34597752
123Ovarian steroidogenesis_Homo sapiens_hsa049130.33521467
124Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.33017542
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.32287167

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