SATL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1binding of sperm to zona pellucida (GO:0007339)9.98902684
2cell-cell recognition (GO:0009988)9.70038947
3epithelial cilium movement (GO:0003351)9.69431718
4reproduction (GO:0000003)9.47711241
5spermatid development (GO:0007286)9.42611158
6axonemal dynein complex assembly (GO:0070286)9.25880148
7regulation of cilium movement (GO:0003352)8.65670875
8motile cilium assembly (GO:0044458)8.59755923
9piRNA metabolic process (GO:0034587)8.50739017
10cilium movement (GO:0003341)7.88260078
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.78860754
12single fertilization (GO:0007338)7.70902334
13male meiosis (GO:0007140)7.45160760
14response to pheromone (GO:0019236)7.09719021
15sperm capacitation (GO:0048240)7.04098482
16negative regulation of inclusion body assembly (GO:0090084)6.89135121
17synaptonemal complex organization (GO:0070193)6.82558316
18fertilization (GO:0009566)6.78504459
19rRNA methylation (GO:0031167)6.74054236
20synaptonemal complex assembly (GO:0007130)6.60419786
21spermatogenesis (GO:0007283)6.55791826
22male gamete generation (GO:0048232)6.53395556
23protein targeting to Golgi (GO:0000042)6.39320936
24microtubule depolymerization (GO:0007019)6.21720105
25establishment of protein localization to Golgi (GO:0072600)6.11458145
26gamete generation (GO:0007276)6.10725751
27organic cation transport (GO:0015695)6.04390295
28rRNA modification (GO:0000154)5.85159946
29retrograde transport, vesicle recycling within Golgi (GO:0000301)5.83849547
30DNA methylation involved in gamete generation (GO:0043046)5.55861172
31regulation of inclusion body assembly (GO:0090083)5.45393447
32germ cell development (GO:0007281)5.37398400
33cellular process involved in reproduction in multicellular organism (GO:0022412)5.33638039
34calcium ion-dependent exocytosis (GO:0017156)5.30899331
35ventricular system development (GO:0021591)5.10969910
36microtubule severing (GO:0051013)5.00086144
37cellular ketone body metabolic process (GO:0046950)4.99913936
38male meiosis I (GO:0007141)4.89693387
39regulation of microtubule-based movement (GO:0060632)4.86048501
40chromosome organization involved in meiosis (GO:0070192)4.82460644
41multicellular organismal reproductive process (GO:0048609)4.82258897
42chromosome condensation (GO:0030261)4.75084101
43regulation of centriole replication (GO:0046599)4.71132357
44protein localization to Golgi apparatus (GO:0034067)4.70891089
45cell recognition (GO:0008037)4.70228913
46glycerol ether metabolic process (GO:0006662)4.56606907
47DNA packaging (GO:0006323)4.46764496
48phosphatidylethanolamine biosynthetic process (GO:0006646)4.45682892
49ketone body metabolic process (GO:1902224)4.40308093
50regulation of Rab GTPase activity (GO:0032313)4.36954590
51positive regulation of Rab GTPase activity (GO:0032851)4.36954590
52phosphatidylethanolamine metabolic process (GO:0046337)4.27668295
53meiotic nuclear division (GO:0007126)4.21666086
54ether metabolic process (GO:0018904)4.19897314
55single strand break repair (GO:0000012)4.16431604
56meiotic cell cycle (GO:0051321)4.14949769
57regulation of transcription involved in cell fate commitment (GO:0060850)4.06350353
58left/right pattern formation (GO:0060972)4.04041174
59spermatid nucleus differentiation (GO:0007289)4.01461179
60seminiferous tubule development (GO:0072520)3.99832925
61chromatin silencing (GO:0006342)3.95191260
62multicellular organismal development (GO:0007275)3.92884938
63microtubule polymerization or depolymerization (GO:0031109)3.86890620
64meiosis I (GO:0007127)3.84039459
65positive regulation of action potential (GO:0045760)3.66437075
66microtubule nucleation (GO:0007020)3.59057706
67negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.55564395
68genitalia morphogenesis (GO:0035112)3.52283576
69coenzyme catabolic process (GO:0009109)3.48928542
70protein polyglutamylation (GO:0018095)3.43102464
71monoubiquitinated protein deubiquitination (GO:0035520)3.40584229
72sequestering of actin monomers (GO:0042989)3.38510478
73negative regulation of Rho protein signal transduction (GO:0035024)3.29991458
74chaperone-mediated protein complex assembly (GO:0051131)3.28925180
75multicellular organismal movement (GO:0050879)3.27961384
76musculoskeletal movement (GO:0050881)3.27961384
77glomerular visceral epithelial cell development (GO:0072015)3.23037576
78protein localization to cilium (GO:0061512)3.21014318
79synapsis (GO:0007129)3.17367911
80antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.15640389
81sexual reproduction (GO:0019953)3.15494624
82cerebral cortex neuron differentiation (GO:0021895)3.12490679
83histone exchange (GO:0043486)3.12200756
84positive regulation of gastrulation (GO:2000543)3.11197023
85negative regulation of organelle assembly (GO:1902116)3.10063110
86protein K11-linked deubiquitination (GO:0035871)3.08451594
87glycolytic process (GO:0006096)3.07499364
88regulation of spindle checkpoint (GO:0090231)3.06847606
89glomerular epithelial cell development (GO:0072310)3.06480695
90cellular response to pH (GO:0071467)3.06149748
91protein refolding (GO:0042026)3.01530874
92meiotic cell cycle process (GO:1903046)3.00224491
93mitotic sister chromatid cohesion (GO:0007064)2.96779841
94RNA localization (GO:0006403)2.95730672
95spinal cord motor neuron differentiation (GO:0021522)2.90805117
96cilium organization (GO:0044782)2.90273969
97response to acidic pH (GO:0010447)2.87469561
98histone H3-K9 demethylation (GO:0033169)2.86342573
99negative regulation of gene expression, epigenetic (GO:0045814)2.84909478
100nephron epithelium morphogenesis (GO:0072088)2.84680379
101nephron tubule morphogenesis (GO:0072078)2.84680379
102positive regulation of guanylate cyclase activity (GO:0031284)2.84390243
103intraciliary transport (GO:0042073)2.83157084
104microtubule-based movement (GO:0007018)2.83061738
105cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.82750171
106alditol metabolic process (GO:0019400)2.82667468
107carnitine transport (GO:0015879)2.82641393
108amino-acid betaine transport (GO:0015838)2.82641393
109cilium assembly (GO:0042384)2.82535146
110nucleoside diphosphate phosphorylation (GO:0006165)2.81251340
111centriole assembly (GO:0098534)2.80343226
112regulation of acrosome reaction (GO:0060046)2.79674151
113cellular component assembly involved in morphogenesis (GO:0010927)2.75963913
114regulation of cilium assembly (GO:1902017)2.74561620
115polyol catabolic process (GO:0046174)2.69667590
116regulation of retinoic acid receptor signaling pathway (GO:0048385)2.69423973
117gene silencing by RNA (GO:0031047)2.69100320
118intra-Golgi vesicle-mediated transport (GO:0006891)2.67166725
119calcium ion import (GO:0070509)2.65111976
120carnitine transmembrane transport (GO:1902603)2.62619202
121regulation of guanylate cyclase activity (GO:0031282)2.61749599
122nucleus organization (GO:0006997)2.59568835
123polyamine biosynthetic process (GO:0006596)2.57562308
124lactate metabolic process (GO:0006089)2.56652685
125cilium morphogenesis (GO:0060271)2.55896650
126RNA destabilization (GO:0050779)2.55881310
127negative regulation of skeletal muscle tissue development (GO:0048642)2.54148944
128regulation of protein kinase C signaling (GO:0090036)2.50508441
129centriole replication (GO:0007099)2.48268647
130regulation of meiosis I (GO:0060631)2.46338003
131axoneme assembly (GO:0035082)2.42632997
132sperm motility (GO:0030317)13.5592460
133fusion of sperm to egg plasma membrane (GO:0007342)13.2158556
134acrosome reaction (GO:0007340)11.5902704
135multicellular organism reproduction (GO:0032504)11.2834456
136sperm-egg recognition (GO:0035036)10.8908145
137cell wall macromolecule catabolic process (GO:0016998)10.8484299
138cell wall macromolecule metabolic process (GO:0044036)10.8484299
139acrosome assembly (GO:0001675)10.5096808
140cilium or flagellum-dependent cell motility (GO:0001539)10.1317673
141plasma membrane fusion (GO:0045026)10.0575849

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse7.11461849
2EZH2_22144423_ChIP-Seq_EOC_Human4.68174150
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse4.51750714
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.14760136
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.72436283
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.52035255
7MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.06085820
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.62028388
9BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.60369468
10VDR_22108803_ChIP-Seq_LS180_Human2.51378965
11CTBP1_25329375_ChIP-Seq_LNCAP_Human2.46531860
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.34870004
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.30724011
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.17752483
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.10420790
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.07036712
17EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.00761528
18ER_23166858_ChIP-Seq_MCF-7_Human1.94149647
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.91347244
20MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.84001346
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.81913649
22UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.81740597
23KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.79452953
24ERA_21632823_ChIP-Seq_H3396_Human1.77744107
25* CBX2_27304074_Chip-Seq_ESCs_Mouse1.75835099
26STAT1_17558387_ChIP-Seq_HELA_Human1.75078034
27EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.73398163
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70384074
29DROSHA_22980978_ChIP-Seq_HELA_Human1.66819234
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.66208195
31P300_19829295_ChIP-Seq_ESCs_Human1.65838783
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64221187
33NANOG_20526341_ChIP-Seq_ESCs_Human1.63646286
34RAC3_21632823_ChIP-Seq_H3396_Human1.62014282
35NFE2_27457419_Chip-Seq_LIVER_Mouse1.61749245
36ETV2_25802403_ChIP-Seq_MESCs_Mouse1.61690356
37KDM2B_26808549_Chip-Seq_REH_Human1.60603683
38TAF2_19829295_ChIP-Seq_ESCs_Human1.58744855
39TAL1_26923725_Chip-Seq_HPCs_Mouse1.58572925
40ELK4_26923725_Chip-Seq_MESODERM_Mouse1.58528077
41TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.57972452
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.57643789
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.57418942
44TAF15_26573619_Chip-Seq_HEK293_Human1.56685047
45SUZ12_27294783_Chip-Seq_NPCs_Mouse1.56596098
46AR_25329375_ChIP-Seq_VCAP_Human1.55535832
47GBX2_23144817_ChIP-Seq_PC3_Human1.53468665
48RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.51929629
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.51343897
50CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.51210551
51TP63_19390658_ChIP-ChIP_HaCaT_Human1.50962102
52CTCF_27219007_Chip-Seq_Bcells_Human1.49387513
53AUTS2_25519132_ChIP-Seq_293T-REX_Human1.48829116
54PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.44135154
55KAP1_22055183_ChIP-Seq_ESCs_Mouse1.43842394
56NANOG_18555785_Chip-Seq_ESCs_Mouse1.41930695
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41248073
58CBP_20019798_ChIP-Seq_JUKART_Human1.41248073
59TDRD3_21172665_ChIP-Seq_MCF-7_Human1.41088419
60EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.39432732
61ZNF274_21170338_ChIP-Seq_K562_Hela1.39067478
62GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.38849749
63* RNF2_27304074_Chip-Seq_NSC_Mouse1.38622503
64TP53_18474530_ChIP-ChIP_U2OS_Human1.38127401
65RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.38098406
66PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.35440395
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.35186735
68CRX_20693478_ChIP-Seq_RETINA_Mouse1.33847859
69FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33805072
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.33754068
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32837218
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32837218
73YY1_22570637_ChIP-Seq_MALME-3M_Human1.32094064
74E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.31805429
75VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.30587109
76CTCF_20526341_ChIP-Seq_ESCs_Human1.30380126
77CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.30289243
78RBPJ_21746931_ChIP-Seq_IB4_Human1.29943054
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29821443
80MYC_19829295_ChIP-Seq_ESCs_Human1.29451036
81REST_21632747_ChIP-Seq_MESCs_Mouse1.29047045
82P53_22387025_ChIP-Seq_ESCs_Mouse1.28601077
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.28466100
84ELF1_20517297_ChIP-Seq_JURKAT_Human1.28449436
85ARNT_22903824_ChIP-Seq_MCF-7_Human1.28429831
86OCT4_20526341_ChIP-Seq_ESCs_Human1.27538524
87BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27315944
88WDR5_24793694_ChIP-Seq_LNCAP_Human1.27087643
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.26861225
90TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25044871
91SOX2_22085726_ChIP-Seq_NPCs_Mouse1.24691538
92SMAD4_21799915_ChIP-Seq_A2780_Human1.24258244
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24169644
94CBX2_22325352_ChIP-Seq_293T-Rex_Human1.24043068
95HNFA_21074721_ChIP-Seq_CACO-2_Human1.23549529
96* EZH2_27304074_Chip-Seq_ESCs_Mouse1.23494496
97CMYC_18555785_Chip-Seq_ESCs_Mouse1.23045590
98GF1_26923725_Chip-Seq_HPCs_Mouse1.22873519
99GATA3_21878914_ChIP-Seq_MCF-7_Human1.22754414
100AR_21572438_ChIP-Seq_LNCaP_Human1.21555567
101OCT4_18555785_Chip-Seq_ESCs_Mouse1.21362704
102NANOG_19829295_ChIP-Seq_ESCs_Human1.21225188
103SOX2_19829295_ChIP-Seq_ESCs_Human1.21225188
104SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20670118
105GATA3_21867929_ChIP-Seq_TH1_Mouse1.19955285
106* E2F1_17053090_ChIP-ChIP_MCF-7_Human1.19457684
107PHF8_20622853_ChIP-Seq_HELA_Human1.19375067
108FLI1_21867929_ChIP-Seq_TH2_Mouse1.19222223
109MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18840277
110RUNX2_22187159_ChIP-Seq_PCA_Human1.18829420
111STAT3_23295773_ChIP-Seq_U87_Human1.18210654
112FUS_26573619_Chip-Seq_HEK293_Human1.17027507
113SMAD3_21741376_ChIP-Seq_ESCs_Human1.16441236
114MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15652597
115ERG_20517297_ChIP-Seq_VCAP_Human1.15336886
116PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.14562530
117P300_18555785_Chip-Seq_ESCs_Mouse1.14485578
118E2F1_20622854_ChIP-Seq_HELA_Human1.14184372
119RUNX1_26923725_Chip-Seq_HPCs_Mouse1.13267877
120SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.13252331
121EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.12844184
122OCT4_21477851_ChIP-Seq_ESCs_Mouse1.11789541
123P53_21459846_ChIP-Seq_SAOS-2_Human1.11698185
124KLF4_18555785_Chip-Seq_ESCs_Mouse1.10154159
125TCF4_18268006_ChIP-ChIP_LS174T_Human1.09914998
126LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.09870605
127GATA3_21867929_ChIP-Seq_CD8_Mouse1.09699092
128PHF8_20622854_ChIP-Seq_HELA_Human1.09448768
129FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09334537
130STAT3_18555785_Chip-Seq_ESCs_Mouse1.09016361
131PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.06660061
132NCOR_22424771_ChIP-Seq_293T_Human1.06109745
133TBL1_22424771_ChIP-Seq_293T_Human1.05296890
134PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.05229053
135FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05112883
136SUZ12_18555785_Chip-Seq_ESCs_Mouse1.04998128
137GATA6_21074721_ChIP-Seq_CACO-2_Human1.04141779
138BCL6_27268052_Chip-Seq_Bcells_Human1.04072104
139FOXA1_25329375_ChIP-Seq_VCAP_Human1.03660346
140FOXA1_27270436_Chip-Seq_PROSTATE_Human1.03660346
141PU1_27457419_Chip-Seq_LIVER_Mouse1.03480836
142ESRRB_18555785_Chip-Seq_ESCs_Mouse1.03442528
143NFYB_21822215_ChIP-Seq_K562_Human1.03436797
144SMAD4_21741376_ChIP-Seq_HESCs_Human1.03357717
145SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.02554706
146TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02458350
147CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02455157
148NFYA_21822215_ChIP-Seq_K562_Human1.02158156
149SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01879848
150SOX2_18555785_Chip-Seq_ESCs_Mouse1.01363927
151TP63_22573176_ChIP-Seq_HFKS_Human1.01116632
152SMAD4_21741376_ChIP-Seq_EPCs_Human1.01005239
153RAD21_21589869_ChIP-Seq_MESCs_Mouse1.00914224
154EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97169367
155E2F1_18555785_Chip-Seq_ESCs_Mouse0.95879924
156CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95544369
157ESET_19884257_ChIP-Seq_ESCs_Mouse0.95283120
158MYC_27129775_Chip-Seq_CORNEA_Mouse0.94518274
159SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94306436
160GF1B_26923725_Chip-Seq_HPCs_Mouse0.94163339
161ETV1_20927104_ChIP-Seq_GIST48_Human0.94063375
162CTCF_18555785_Chip-Seq_ESCs_Mouse0.93121628
163CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.92273982
164NMYC_18555785_Chip-Seq_ESCs_Mouse0.91510144
165SPI1_26923725_Chip-Seq_HPCs_Mouse0.90959169
166RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89905715
167PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89636399
168EZH2_27294783_Chip-Seq_ESCs_Mouse0.89293397
169OCT1_27270436_Chip-Seq_PROSTATE_Human0.88966930

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.78644719
2MP0001929_abnormal_gametogenesis5.38116133
3MP0008877_abnormal_DNA_methylation4.37350166
4MP0003283_abnormal_digestive_organ3.35982010
5MP0002161_abnormal_fertility/fecundity3.33146062
6MP0002210_abnormal_sex_determination3.33091098
7MP0005670_abnormal_white_adipose2.86819540
8MP0005423_abnormal_somatic_nervous2.77531022
9MP0001145_abnormal_male_reproductive2.73263607
10MP0000653_abnormal_sex_gland2.51476348
11MP0003646_muscle_fatigue2.50459594
12MP0001348_abnormal_lacrimal_gland2.29928668
13MP0002653_abnormal_ependyma_morphology2.06552374
14MP0005410_abnormal_fertilization15.2217452
15MP0009379_abnormal_foot_pigmentation1.98147706
16MP0001485_abnormal_pinna_reflex1.83025186
17MP0006292_abnormal_olfactory_placode1.74952362
18MP0002282_abnormal_trachea_morphology1.70122872
19MP0004859_abnormal_synaptic_plasticity1.66456845
20MP0003950_abnormal_plasma_membrane1.66110134
21MP0000566_synostosis1.65944155
22MP0002822_catalepsy1.62770513
23MP0005379_endocrine/exocrine_gland_phen1.57555807
24MP0002160_abnormal_reproductive_system1.47293859
25MP0002938_white_spotting1.45565233
26MP0002249_abnormal_larynx_morphology1.37547663
27MP0004142_abnormal_muscle_tone1.31393534
28MP0005623_abnormal_meninges_morphology1.27736410
29MP0000678_abnormal_parathyroid_gland1.27071318
30MP0002132_abnormal_respiratory_system1.26503499
31MP0009745_abnormal_behavioral_response1.24337719
32MP0005451_abnormal_body_composition1.22749770
33MP0003122_maternal_imprinting1.21107897
34MP0000026_abnormal_inner_ear1.19464234
35MP0006276_abnormal_autonomic_nervous1.18374407
36MP0004134_abnormal_chest_morphology1.14560806
37MP0005248_abnormal_Harderian_gland1.13813473
38MP0001765_abnormal_ion_homeostasis1.12476283
39MP0002557_abnormal_social/conspecific_i1.12259601
40MP0002064_seizures1.06277131
41MP0004233_abnormal_muscle_weight1.04511406
42MP0002067_abnormal_sensory_capabilities1.02943735
43MP0001440_abnormal_grooming_behavior1.01535667
44MP0003635_abnormal_synaptic_transmissio1.01230522
45MP0009053_abnormal_anal_canal0.99773278
46MP0009697_abnormal_copulation0.94630841
47MP0003119_abnormal_digestive_system0.93638016
48MP0005647_abnormal_sex_gland0.93130849
49MP0003136_yellow_coat_color0.93086716
50MP0002928_abnormal_bile_duct0.92336829
51MP0009046_muscle_twitch0.92114004
52MP0005084_abnormal_gallbladder_morpholo0.91709453
53MP0000462_abnormal_digestive_system0.91329752
54MP0003121_genomic_imprinting0.84906418
55MP0002733_abnormal_thermal_nociception0.84201148
56MP0005389_reproductive_system_phenotype0.84105968
57MP0000778_abnormal_nervous_system0.83431672
58MP0002063_abnormal_learning/memory/cond0.83012516
59MP0002837_dystrophic_cardiac_calcinosis0.82544870
60MP0008961_abnormal_basal_metabolism0.81133303
61MP0003718_maternal_effect0.78890503
62MP0003699_abnormal_female_reproductive0.77710014
63MP0000920_abnormal_myelination0.74337387
64MP0002127_abnormal_cardiovascular_syste0.74122319
65MP0004510_myositis0.72730847
66MP0004145_abnormal_muscle_electrophysio0.71715240
67MP0005167_abnormal_blood-brain_barrier0.70205912
68MP0001986_abnormal_taste_sensitivity0.70084559
69MP0004133_heterotaxia0.69766723
70MP0005551_abnormal_eye_electrophysiolog0.69696267
71MP0001984_abnormal_olfaction0.69696108
72MP0001346_abnormal_lacrimal_gland0.68246374
73MP0001970_abnormal_pain_threshold0.66983135
74MP0005499_abnormal_olfactory_system0.66473601
75MP0005394_taste/olfaction_phenotype0.66473601
76MP0008058_abnormal_DNA_repair0.66280939
77MP0000751_myopathy0.65279686
78MP0002184_abnormal_innervation0.65059801
79MP0005666_abnormal_adipose_tissue0.64294243
80MP0003137_abnormal_impulse_conducting0.62560161
81MP0010094_abnormal_chromosome_stability0.62558586
82MP0000569_abnormal_digit_pigmentation0.60979171
83MP0003787_abnormal_imprinting0.60920379
84MP0001119_abnormal_female_reproductive0.60553773
85MP0005310_abnormal_salivary_gland0.58884414
86MP0008789_abnormal_olfactory_epithelium0.58809431
87MP0004742_abnormal_vestibular_system0.58138191
88MP0002295_abnormal_pulmonary_circulatio0.56930491
89MP0002234_abnormal_pharynx_morphology0.56428109
90MP0003880_abnormal_central_pattern0.56131661
91MP0003879_abnormal_hair_cell0.54115507
92MP0003942_abnormal_urinary_system0.53153622
93MP0005083_abnormal_biliary_tract0.52590081
94MP0005253_abnormal_eye_physiology0.51477942
95MP0005377_hearing/vestibular/ear_phenot0.50405929
96MP0003878_abnormal_ear_physiology0.50405929
97MP0005408_hypopigmentation0.50184747
98MP0002102_abnormal_ear_morphology0.49699706
99MP0008057_abnormal_DNA_replication0.48981217
100MP0004036_abnormal_muscle_relaxation0.48607123
101MP0001486_abnormal_startle_reflex0.48432266
102MP0000534_abnormal_ureter_morphology0.48187915
103MP0002269_muscular_atrophy0.47715453
104MP0002736_abnormal_nociception_after0.47375278
105MP0009250_abnormal_appendicular_skeleto0.47105989
106MP0005636_abnormal_mineral_homeostasis0.44801812
107MP0003329_amyloid_beta_deposits0.44644258
108MP0003115_abnormal_respiratory_system0.44568821
109MP0004270_analgesia0.43508832
110MP0006072_abnormal_retinal_apoptosis0.41326012
111MP0002735_abnormal_chemical_nociception0.37723288
112MP0003195_calcinosis0.36095817
113MP0001905_abnormal_dopamine_level0.35608378
114MP0005395_other_phenotype0.34699873
115MP0002272_abnormal_nervous_system0.34241933
116MP0005391_vision/eye_phenotype0.34166888
117MP0000955_abnormal_spinal_cord0.33803000
118MP0000579_abnormal_nail_morphology0.32886461
119MP0003861_abnormal_nervous_system0.32792683
120MP0002752_abnormal_somatic_nervous0.31920534
121MP0002734_abnormal_mechanical_nocicepti0.30937787
122MP0000049_abnormal_middle_ear0.30258773
123MP0002229_neurodegeneration0.30188522
124MP0002152_abnormal_brain_morphology0.29984894
125MP0001529_abnormal_vocalization0.29924970
126MP0002109_abnormal_limb_morphology0.29239897
127MP0000427_abnormal_hair_cycle0.29107208
128MP0004811_abnormal_neuron_physiology0.29023261
129MP0004019_abnormal_vitamin_homeostasis0.28681798
130MP0001968_abnormal_touch/_nociception0.28457475
131MP0008995_early_reproductive_senescence0.28386462
132MP0001963_abnormal_hearing_physiology0.28166397
133MP0001324_abnormal_eye_pigmentation0.27546981
134MP0000639_abnormal_adrenal_gland0.27174200
135MP0008007_abnormal_cellular_replicative0.26686527
136MP0001727_abnormal_embryo_implantation0.26550416
137MP0009115_abnormal_fat_cell0.26455447
138MP0005646_abnormal_pituitary_gland0.25996152
139MP0005171_absent_coat_pigmentation0.25891079
140MP0002971_abnormal_brown_adipose0.25333685
141MP0002114_abnormal_axial_skeleton0.25079435
142MP0002882_abnormal_neuron_morphology0.24560588
143MP0003011_delayed_dark_adaptation0.22946671
144MP0005195_abnormal_posterior_eye0.22447800
145MP0002572_abnormal_emotion/affect_behav0.22302898
146MP0001764_abnormal_homeostasis0.21318777
147MP0006036_abnormal_mitochondrial_physio0.21050792
148MP0008569_lethality_at_weaning0.20801216
149MP0001293_anophthalmia0.20603350
150MP0003937_abnormal_limbs/digits/tail_de0.20485383

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.82253793
2Abnormal respiratory motile cilium morphology (HP:0005938)8.68560901
3Abnormal respiratory epithelium morphology (HP:0012253)8.68560901
4Abnormal ciliary motility (HP:0012262)7.15170322
5Infertility (HP:0000789)6.84177392
6Rhinitis (HP:0012384)6.77082435
7Chronic bronchitis (HP:0004469)6.59471841
8Male infertility (HP:0003251)5.74958999
9Severe visual impairment (HP:0001141)5.47518482
10Nasal polyposis (HP:0100582)5.42679702
11Nephronophthisis (HP:0000090)4.66107265
12Abnormality of the nasal mucosa (HP:0000433)4.36072898
13Bony spicule pigmentary retinopathy (HP:0007737)4.35414862
14Attenuation of retinal blood vessels (HP:0007843)4.29825271
15Bronchitis (HP:0012387)4.25512969
16Chronic hepatic failure (HP:0100626)4.16695151
17Bronchiectasis (HP:0002110)4.13926559
18Abnormality of macular pigmentation (HP:0008002)3.86120623
19Hypoplastic ischia (HP:0003175)3.85386104
20Abnormal rod and cone electroretinograms (HP:0008323)3.70456592
21Abnormal spermatogenesis (HP:0008669)3.68324423
22Abnormality of the renal medulla (HP:0100957)3.56601593
23Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.50309706
24Abnormality of the ischium (HP:0003174)3.43862639
25Myokymia (HP:0002411)3.31696442
26Enlarged epiphyses (HP:0010580)3.26766189
27Hyperkalemia (HP:0002153)3.22467371
28Recurrent sinusitis (HP:0011108)3.15391962
29Resting tremor (HP:0002322)3.14933947
30Renal Fanconi syndrome (HP:0001994)3.09543585
31Recurrent otitis media (HP:0000403)3.08290910
32Potter facies (HP:0002009)3.07000066
33Facial shape deformation (HP:0011334)3.07000066
34Progressive cerebellar ataxia (HP:0002073)3.00799550
35Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.99481423
36Hypoplasia of the thymus (HP:0000778)2.87214289
37Tubulointerstitial nephritis (HP:0001970)2.84889546
38Cone-rod dystrophy (HP:0000548)2.76915875
39Recurrent bronchitis (HP:0002837)2.69540387
40Aplasia/Hypoplasia of the earlobes (HP:0009906)2.65430464
41Postural instability (HP:0002172)2.62072831
42Abnormality of the pubic bones (HP:0003172)2.52869704
43Impulsivity (HP:0100710)2.51638258
44Abnormality of renal resorption (HP:0011038)2.45020044
45Tubular atrophy (HP:0000092)2.42810553
46Abnormal gallbladder physiology (HP:0012438)2.42285633
47Cholecystitis (HP:0001082)2.42285633
48Tubulointerstitial abnormality (HP:0001969)2.41333308
49Unilateral renal agenesis (HP:0000122)2.41132097
50Abnormality of abdominal situs (HP:0011620)2.40731732
51Abdominal situs inversus (HP:0003363)2.40731732
52Pancreatic fibrosis (HP:0100732)2.40009241
53Abnormality of midbrain morphology (HP:0002418)2.35708061
54Molar tooth sign on MRI (HP:0002419)2.35708061
55Abnormality of dental color (HP:0011073)2.31724325
56Progressive sensorineural hearing impairment (HP:0000408)2.29819727
57Abnormality of urine glucose concentration (HP:0011016)2.29385723
58Glycosuria (HP:0003076)2.29385723
59Amelogenesis imperfecta (HP:0000705)2.27560201
60Pancreatic cysts (HP:0001737)2.25236297
61Hypoplasia of the capital femoral epiphysis (HP:0003090)2.22814750
62Sclerocornea (HP:0000647)2.22792036
63Aplasia/Hypoplasia of the sacrum (HP:0008517)2.22027948
64Short ribs (HP:0000773)2.21660916
65Generalized aminoaciduria (HP:0002909)2.15615923
66Pendular nystagmus (HP:0012043)2.11626822
67Genetic anticipation (HP:0003743)2.10915026
68Decreased central vision (HP:0007663)2.09711305
69Absent epiphyses (HP:0010577)2.09019392
70Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.09019392
71Azoospermia (HP:0000027)2.08814227
72Atonic seizures (HP:0010819)2.05532967
73Gonadotropin excess (HP:0000837)2.05492446
74Esophageal atresia (HP:0002032)2.04713669
75Failure to thrive in infancy (HP:0001531)2.04385146
76Medial flaring of the eyebrow (HP:0010747)2.03823173
77Postaxial foot polydactyly (HP:0001830)2.03653560
78Truncal obesity (HP:0001956)2.02046064
79Focal segmental glomerulosclerosis (HP:0000097)2.00506701
80Peripheral hypomyelination (HP:0007182)2.00501782
81Absent/shortened dynein arms (HP:0200106)13.2039290
82Dynein arm defect of respiratory motile cilia (HP:0012255)13.2039290
83Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2360786
84Hypoalphalipoproteinemia (HP:0003233)1.99841378
85Recurrent corneal erosions (HP:0000495)1.99431521
86Abnormal drinking behavior (HP:0030082)1.99373257
87Polydipsia (HP:0001959)1.99373257
88Flat capital femoral epiphysis (HP:0003370)1.98585477
89Double outlet right ventricle (HP:0001719)1.95862177
90Congenital malformation of the right heart (HP:0011723)1.95862177
91Renovascular hypertension (HP:0100817)1.95533689
92Stage 5 chronic kidney disease (HP:0003774)1.95217389
93Menstrual irregularities (HP:0000858)1.92721660
94Focal motor seizures (HP:0011153)1.91990837
95Tubulointerstitial fibrosis (HP:0005576)1.89834422
96Abnormality of the aortic arch (HP:0012303)1.88884927
97Sensory axonal neuropathy (HP:0003390)1.88634922
98Abnormality of the costochondral junction (HP:0000919)1.87526171
99Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.87491749
100Choroideremia (HP:0001139)1.86842061
101Short femoral neck (HP:0100864)1.86416346
102Gastrointestinal atresia (HP:0002589)1.85140790
103Congenital sensorineural hearing impairment (HP:0008527)1.84750534
104Spastic tetraparesis (HP:0001285)1.83932668
105Abnormality of the renal cortex (HP:0011035)1.81562736
106Insulin-resistant diabetes mellitus (HP:0000831)1.80777560
107Heterotopia (HP:0002282)1.79988766
108Neurofibrillary tangles (HP:0002185)1.79744380
109Dyschromatopsia (HP:0007641)1.79560382
110Acute necrotizing encephalopathy (HP:0006965)1.76839157
111Flattened epiphyses (HP:0003071)1.76661439
112Abnormality of permanent molar morphology (HP:0011071)1.75280951
113Abnormality of the dental root (HP:0006486)1.75280951
114Taurodontia (HP:0000679)1.75280951
115Osteomalacia (HP:0002749)1.74922023
116Vertebral clefting (HP:0008428)1.74796791
117Congenital hepatic fibrosis (HP:0002612)1.69450066
118Abnormality of renal excretion (HP:0011036)1.68819017
119Abnormality of dentin (HP:0010299)1.67452587
120Abnormality of molar morphology (HP:0011070)1.66811731
121Abnormality of molar (HP:0011077)1.66811731
122J-shaped sella turcica (HP:0002680)1.63767965
123Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.60208944
124Abnormality of the dental pulp (HP:0006479)1.57025175
125Bell-shaped thorax (HP:0001591)1.55693882
126Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.55643142
127Short thorax (HP:0010306)1.54065782
128Decreased electroretinogram (ERG) amplitude (HP:0000654)1.51940624
129Asymmetric septal hypertrophy (HP:0001670)1.49554331
130Hemorrhage of the eye (HP:0011885)1.49506430
131Postaxial hand polydactyly (HP:0001162)1.47650616
132Abnormal biliary tract physiology (HP:0012439)1.45232775
133Bile duct proliferation (HP:0001408)1.45232775
134Abnormality of the epiphysis of the femoral head (HP:0010574)1.44746090
135Abnormal urine output (HP:0012590)1.43179396
136Abnormality of the epiphyses of the hand (HP:0005924)1.42629627
137Deformed sella turcica (HP:0002681)1.41828892
138Fibular hypoplasia (HP:0003038)1.40855449
139Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.34723240
140Abnormality of femoral epiphyses (HP:0006499)1.34723240
141Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.33698178
142Bundle branch block (HP:0011710)1.33102983
143Cerebral inclusion bodies (HP:0100314)1.32428096
144Renal dysplasia (HP:0000110)1.32372672
145Supernumerary spleens (HP:0009799)1.31010630
146Hemiparesis (HP:0001269)1.30561071
147Absent frontal sinuses (HP:0002688)1.29550164
148Abnormality of the femoral head (HP:0003368)1.28503099
149Broad distal phalanx of finger (HP:0009836)1.28245634
150Neoplasm of the heart (HP:0100544)1.27604575
151Loss of speech (HP:0002371)1.26701240
152Abnormal vertebral ossification (HP:0100569)1.26312967
153Retinal dysplasia (HP:0007973)1.26243961
154Polyuria (HP:0000103)1.23722398
155Aplasia/Hypoplasia of the lens (HP:0008063)1.21903650
156Optic nerve hypoplasia (HP:0000609)1.19946784
157Vascular calcification (HP:0004934)1.18005121
158Abnormality of the sella turcica (HP:0002679)1.17680891
159Cystic liver disease (HP:0006706)1.16633282
160Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.15529235
161Aplasia/hypoplasia of the femur (HP:0005613)1.15528411
162Glucose intolerance (HP:0000833)1.14919747

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.48506348
2PDK37.48506348
3PRKD35.21685783
4TESK15.14096610
5ICK5.05661306
6PDK24.81147634
7MAP4K24.26896247
8INSRR3.92847631
9STK393.37886623
10PLK23.12380350
11WNK42.92271225
12BRD42.71211113
13PNCK2.10072515
14PTK2B2.07750973
15NME11.73268124
16VRK21.64094811
17DYRK1B1.61933513
18STK381.50932846
19BRSK21.50662777
20PIK3CG1.46543582
21MAP3K91.38306446
22FRK1.36978650
23WNK11.29949583
24NEK21.22727152
25PDK11.18186922
26TTK1.17261927
27BRSK11.16364845
28CDK191.00671600
29STK38L0.98403859
30CDK70.97932892
31MARK10.92452291
32MAP3K110.90533664
33CAMK1G0.87657159
34MAP3K130.86779370
35MST1R0.86495330
36PRPF4B0.85664368
37NTRK20.84106233
38STK30.82592850
39CDC70.82060538
40TYRO30.81333927
41VRK10.80836242
42NTRK30.80723515
43PDPK10.78012902
44MAPK150.74685879
45NEK60.73776953
46SIK20.73403363
47CHEK20.70078448
48MAP2K40.69798497
49TIE10.67944322
50DYRK30.64337038
51TESK20.63674812
52CAMK10.63402445
53MAP3K60.62144242
54TLK10.59063856
55MUSK0.58903092
56PAK20.57513745
57FGFR20.57388267
58PAK60.57362866
59BMPR1B0.55482125
60DMPK0.54224755
61BMPR20.52627541
62MAPKAPK50.49889670
63TRIM280.47915353
64RPS6KA20.47659066
65CASK0.46370603
66CAMK1D0.43764557
67CLK10.43718291
68CCNB10.43644833
69BRAF0.42766786
70STK240.40946205
71PLK40.40693756
72CDK20.39684677
73BUB10.39291562
74PRKCQ0.39229851
75RPS6KA10.38677809
76KSR20.38118029
77GRK10.38032333
78MAP3K40.36299349
79EPHB10.35886141
80PASK0.35436594
81TAOK30.34713284
82ATM0.34613335
83RIPK40.34440065
84EEF2K0.34410394
85PAK10.34085531
86PKN10.33666121
87MAP2K60.32558375
88DYRK1A0.31550332
89MAP3K80.31524253
90RPS6KA60.31180517
91MINK10.31117354
92PLK30.31040679
93CHEK10.30765297
94STK100.30474115
95DYRK20.29714505
96PRKCG0.29447650
97EPHA40.29262197
98MAP3K20.29245194
99PRKAA10.29203852
100LATS10.28582900
101ZAK0.28505882
102PINK10.28505806
103LATS20.28478443
104CDK150.26963187
105MAPK80.26592776
106CAMK40.25411924
107IRAK10.25407977
108SGK20.24652738
109MAP3K70.23530787
110CDK180.23454909
111MAPK10.23127229
112TNIK0.22835778
113SGK10.22690121
114PRKCE0.22613914
115ERBB40.22600279
116CDK30.22552222
117PLK10.22492452
118PRKCB0.22082354
119ADRBK20.21799137
120AKT10.21745169
121OXSR10.21163634
122CDK140.20822342
123CDK11A0.19551260
124MARK20.18786084
125LMTK20.18298165
126MOS0.17801667
127PRKAA20.16881327
128ATR0.16877377
129PRKCZ0.16844425
130CSNK1D0.16366140
131MTOR0.15214758
132DDR20.13793606
133SGK2230.13520577
134SGK4940.13520577
135ROCK10.13384439
136MELK0.13083176
137PRKG10.11847386
138CAMKK10.10346925
139GSK3B0.10235541
140CAMK2A0.10021393
141MAP2K70.09685329
142CDK10.08956913
143MAPK100.06938017
144ROCK20.06289481
145MAPK130.05775301
146WNK30.05028280
147UHMK10.03877373
148PRKCA0.03738435
149PRKACA0.03459326
150NEK90.03103007
151PRKD20.02437886
152AURKA0.02339026

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.96977864
2Fatty acid biosynthesis_Homo sapiens_hsa000614.64713988
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.10390754
4Olfactory transduction_Homo sapiens_hsa047403.44634963
5Vitamin B6 metabolism_Homo sapiens_hsa007503.30329656
6Pyruvate metabolism_Homo sapiens_hsa006203.11339788
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.97855410
8Linoleic acid metabolism_Homo sapiens_hsa005912.91017686
9Propanoate metabolism_Homo sapiens_hsa006402.61594253
10Butanoate metabolism_Homo sapiens_hsa006502.55361946
11Oxidative phosphorylation_Homo sapiens_hsa001902.47525640
12Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.32537708
13Dorso-ventral axis formation_Homo sapiens_hsa043202.24332651
14Glucagon signaling pathway_Homo sapiens_hsa049222.22631044
15Basal transcription factors_Homo sapiens_hsa030222.20726178
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.17387270
17Maturity onset diabetes of the young_Homo sapiens_hsa049502.13844660
18Ribosome_Homo sapiens_hsa030102.06219587
19Carbohydrate digestion and absorption_Homo sapiens_hsa049732.05804962
20Glycosaminoglycan degradation_Homo sapiens_hsa005312.02487519
21Ether lipid metabolism_Homo sapiens_hsa005651.81791164
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.78770262
23Glycerolipid metabolism_Homo sapiens_hsa005611.78231425
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.75742401
25Fanconi anemia pathway_Homo sapiens_hsa034601.75577734
26Parkinsons disease_Homo sapiens_hsa050121.72148788
27Phototransduction_Homo sapiens_hsa047441.69336895
28Selenocompound metabolism_Homo sapiens_hsa004501.68449442
29PPAR signaling pathway_Homo sapiens_hsa033201.67613148
30Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.61034420
31Oocyte meiosis_Homo sapiens_hsa041141.60452056
32Glycerophospholipid metabolism_Homo sapiens_hsa005641.60214982
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.59481506
34Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.55629703
35Fatty acid metabolism_Homo sapiens_hsa012121.49885080
36Mineral absorption_Homo sapiens_hsa049781.40943851
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.39093345
38Fatty acid degradation_Homo sapiens_hsa000711.36353207
39Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.32346450
40Alzheimers disease_Homo sapiens_hsa050101.30893478
41Homologous recombination_Homo sapiens_hsa034401.29651481
42Cardiac muscle contraction_Homo sapiens_hsa042601.21971371
43Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.20244227
44Amphetamine addiction_Homo sapiens_hsa050311.17019902
45GABAergic synapse_Homo sapiens_hsa047271.16810053
46Ovarian steroidogenesis_Homo sapiens_hsa049131.13536819
47RNA polymerase_Homo sapiens_hsa030201.07008390
48Fructose and mannose metabolism_Homo sapiens_hsa000511.07002350
49Glutathione metabolism_Homo sapiens_hsa004801.05549711
50Cyanoamino acid metabolism_Homo sapiens_hsa004601.01508571
51Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01214390
52Hedgehog signaling pathway_Homo sapiens_hsa043400.99294095
53Primary bile acid biosynthesis_Homo sapiens_hsa001200.98610917
54Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.96383847
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.95287188
56Pentose phosphate pathway_Homo sapiens_hsa000300.92080755
57Renin secretion_Homo sapiens_hsa049240.90915571
58Arachidonic acid metabolism_Homo sapiens_hsa005900.90602002
59Serotonergic synapse_Homo sapiens_hsa047260.87454708
60Type I diabetes mellitus_Homo sapiens_hsa049400.87111496
61Purine metabolism_Homo sapiens_hsa002300.85413402
62Collecting duct acid secretion_Homo sapiens_hsa049660.84961527
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.82578216
64Fat digestion and absorption_Homo sapiens_hsa049750.82109029
65Protein digestion and absorption_Homo sapiens_hsa049740.81877659
66Proteasome_Homo sapiens_hsa030500.81423709
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77389316
68Huntingtons disease_Homo sapiens_hsa050160.77207707
69Bile secretion_Homo sapiens_hsa049760.77074260
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74516424
71Endocytosis_Homo sapiens_hsa041440.73926104
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72265813
73Carbon metabolism_Homo sapiens_hsa012000.71750165
74Arginine and proline metabolism_Homo sapiens_hsa003300.71465497
75Insulin secretion_Homo sapiens_hsa049110.71375378
76Phenylalanine metabolism_Homo sapiens_hsa003600.70662285
77ABC transporters_Homo sapiens_hsa020100.70370370
78Nucleotide excision repair_Homo sapiens_hsa034200.69858510
79Cholinergic synapse_Homo sapiens_hsa047250.69353547
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.69341499
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.69017307
82Inositol phosphate metabolism_Homo sapiens_hsa005620.68238609
83Axon guidance_Homo sapiens_hsa043600.65276919
84Cocaine addiction_Homo sapiens_hsa050300.64804643
85Calcium signaling pathway_Homo sapiens_hsa040200.64641460
86Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63697048
87mRNA surveillance pathway_Homo sapiens_hsa030150.61482968
88Antigen processing and presentation_Homo sapiens_hsa046120.59876392
89Mismatch repair_Homo sapiens_hsa034300.59060616
90Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58692480
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.56849380
92Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.56007109
93Estrogen signaling pathway_Homo sapiens_hsa049150.55464884
94Salivary secretion_Homo sapiens_hsa049700.55423069
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53750296
96Sulfur metabolism_Homo sapiens_hsa009200.53404773
97Synaptic vesicle cycle_Homo sapiens_hsa047210.52985194
98Dopaminergic synapse_Homo sapiens_hsa047280.52613632
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52495734
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.52413151
101Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51129398
102Sphingolipid metabolism_Homo sapiens_hsa006000.50916347
103Thyroid hormone synthesis_Homo sapiens_hsa049180.49341273
104Steroid biosynthesis_Homo sapiens_hsa001000.48284468
105cAMP signaling pathway_Homo sapiens_hsa040240.48005316
106AMPK signaling pathway_Homo sapiens_hsa041520.45521941
107Autoimmune thyroid disease_Homo sapiens_hsa053200.44980774
108Cell cycle_Homo sapiens_hsa041100.43187830
109Tyrosine metabolism_Homo sapiens_hsa003500.42675589
110Nicotine addiction_Homo sapiens_hsa050330.42590284
111RNA transport_Homo sapiens_hsa030130.41357714
112Chemical carcinogenesis_Homo sapiens_hsa052040.39662350
113Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.39477308
114DNA replication_Homo sapiens_hsa030300.39131409
115beta-Alanine metabolism_Homo sapiens_hsa004100.39026700
116Biosynthesis of amino acids_Homo sapiens_hsa012300.38647281
117Pancreatic secretion_Homo sapiens_hsa049720.38388311
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38178141
119Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.38020267
120Non-homologous end-joining_Homo sapiens_hsa034500.38011533
121Alcoholism_Homo sapiens_hsa050340.37410126
122Allograft rejection_Homo sapiens_hsa053300.36308671
123Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34915931
124Glutamatergic synapse_Homo sapiens_hsa047240.34432831
125Metabolic pathways_Homo sapiens_hsa011000.33726768
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.29924351
127RNA degradation_Homo sapiens_hsa030180.29104291
128Circadian entrainment_Homo sapiens_hsa047130.29042848
129Retinol metabolism_Homo sapiens_hsa008300.28965446
130Pyrimidine metabolism_Homo sapiens_hsa002400.28645989
131Long-term potentiation_Homo sapiens_hsa047200.28276899
132Nitrogen metabolism_Homo sapiens_hsa009100.27393113
133VEGF signaling pathway_Homo sapiens_hsa043700.27242023
134Gastric acid secretion_Homo sapiens_hsa049710.26408571
135Tight junction_Homo sapiens_hsa045300.25592114
136Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25192427
137Wnt signaling pathway_Homo sapiens_hsa043100.25190978
138Basal cell carcinoma_Homo sapiens_hsa052170.24485716
139Morphine addiction_Homo sapiens_hsa050320.24271515
140Type II diabetes mellitus_Homo sapiens_hsa049300.23970727
141Vitamin digestion and absorption_Homo sapiens_hsa049770.19288092
142Taste transduction_Homo sapiens_hsa047420.17716338

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »