SBF1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule metabolic process (GO:0044036)8.06177677
2regulation of short-term neuronal synaptic plasticity (GO:0048172)7.96010504
3neuron recognition (GO:0008038)7.53668757
4pyrimidine nucleobase catabolic process (GO:0006208)6.98076187
5cellular response to nicotine (GO:0071316)6.80700303
6mechanosensory behavior (GO:0007638)6.48652869
7neurotransmitter-gated ion channel clustering (GO:0072578)6.32814520
8nucleobase catabolic process (GO:0046113)5.76495216
9positive regulation of chemokine secretion (GO:0090197)5.43133636
10adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.35310038
11auditory behavior (GO:0031223)5.22334994
12regulation of glycogen (starch) synthase activity (GO:2000465)5.03394058
13synaptic vesicle maturation (GO:0016188)5.00020743
14glucosamine-containing compound catabolic process (GO:1901072)4.98285096
15production of molecular mediator involved in inflammatory response (GO:0002532)4.91961184
16regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.75229561
17regulation of chemokine secretion (GO:0090196)4.68138356
18positive regulation of guanylate cyclase activity (GO:0031284)4.47181124
19calcium ion import (GO:0070509)4.32359200
20positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.30907067
21neuronal ion channel clustering (GO:0045161)4.26712858
22regulation of guanylate cyclase activity (GO:0031282)4.17471832
23membrane depolarization during action potential (GO:0086010)4.16480037
24mitochondrial calcium ion transport (GO:0006851)4.12308712
25establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.04259233
26mitochondrion transport along microtubule (GO:0047497)4.04259233
27epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.97753123
28water-soluble vitamin biosynthetic process (GO:0042364)3.97214077
29vocalization behavior (GO:0071625)3.93654038
30response to auditory stimulus (GO:0010996)3.88308117
31nephron tubule morphogenesis (GO:0072078)3.87189862
32nephron epithelium morphogenesis (GO:0072088)3.87189862
33transmission of nerve impulse (GO:0019226)3.83599384
34establishment of mitochondrion localization (GO:0051654)3.79501852
35regulation of rhodopsin mediated signaling pathway (GO:0022400)3.78231564
36membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.70099795
37cilium or flagellum-dependent cell motility (GO:0001539)3.65685385
38receptor guanylyl cyclase signaling pathway (GO:0007168)3.64754806
39positive regulation of synapse maturation (GO:0090129)3.57592743
40neural tube formation (GO:0001841)3.47002837
41rhodopsin mediated signaling pathway (GO:0016056)3.41430261
42potassium ion import (GO:0010107)3.40807157
43regulation of synapse structural plasticity (GO:0051823)3.36481863
44axonal fasciculation (GO:0007413)3.34646014
45regulation of glutamate receptor signaling pathway (GO:1900449)3.25919667
46negative regulation of axon extension involved in axon guidance (GO:0048843)3.24224355
47protein localization to cilium (GO:0061512)3.19129778
48axon extension (GO:0048675)3.14007533
49positive regulation of action potential (GO:0045760)3.08359306
50protein localization to synapse (GO:0035418)3.06852662
51regulation of synapse maturation (GO:0090128)3.06642381
52glucocorticoid receptor signaling pathway (GO:0042921)3.05333831
53positive regulation of gastrulation (GO:2000543)3.03229784
54presynaptic membrane organization (GO:0097090)3.02554047
55arginine catabolic process (GO:0006527)2.99763558
56adult walking behavior (GO:0007628)2.99420214
57dendrite morphogenesis (GO:0048813)2.97355037
58mitochondrial calcium ion homeostasis (GO:0051560)2.96861955
59renal tubule morphogenesis (GO:0061333)2.96109507
60negative regulation of mast cell activation (GO:0033004)2.95852424
61synapse assembly (GO:0007416)2.94293565
62presynaptic membrane assembly (GO:0097105)2.91527959
63synaptic transmission, glutamatergic (GO:0035249)2.89920766
64negative regulation of axon guidance (GO:1902668)2.87503259
65mitochondrial respiratory chain complex I assembly (GO:0032981)2.87203752
66NADH dehydrogenase complex assembly (GO:0010257)2.87203752
67mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.87203752
68amino sugar catabolic process (GO:0046348)2.86998053
69retinal cone cell development (GO:0046549)2.84464634
70regulation of chromatin binding (GO:0035561)2.82845913
71positive regulation of cGMP biosynthetic process (GO:0030828)2.82011557
72positive regulation of cation channel activity (GO:2001259)2.79964768
73dendritic spine morphogenesis (GO:0060997)2.78582667
74synaptic vesicle docking involved in exocytosis (GO:0016081)2.74747647
75L-ascorbic acid metabolic process (GO:0019852)2.74661766
76negative regulation of glycogen metabolic process (GO:0070874)2.72799919
77regulation of cGMP biosynthetic process (GO:0030826)2.71940929
78response to caffeine (GO:0031000)2.69589028
79neuron cell-cell adhesion (GO:0007158)2.68981314
80righting reflex (GO:0060013)2.67676269
81negative regulation of sodium ion transport (GO:0010766)2.64709226
82positive regulation of microtubule polymerization (GO:0031116)2.63036796
83regulation of NFAT protein import into nucleus (GO:0051532)2.62297601
84glycosphingolipid biosynthetic process (GO:0006688)2.61889510
85neuronal action potential (GO:0019228)2.60892135
86cell recognition (GO:0008037)2.59339953
87neuron projection extension (GO:1990138)2.58098498
88response to ischemia (GO:0002931)2.57884213
89cilium morphogenesis (GO:0060271)2.57223036
90sex differentiation (GO:0007548)2.52937395
91microtubule severing (GO:0051013)2.51981206
92positive regulation of actin filament depolymerization (GO:0030836)2.50688114
93positive regulation of cyclase activity (GO:0031281)2.49159054
94dendrite development (GO:0016358)2.48708900
95N-glycan processing (GO:0006491)2.47462146
96negative regulation of transcription regulatory region DNA binding (GO:2000678)2.46109164
97sequestering of actin monomers (GO:0042989)2.44830490
98glucosamine-containing compound metabolic process (GO:1901071)2.44501960
99synapse organization (GO:0050808)2.43315233
100opioid receptor signaling pathway (GO:0038003)16.0911101

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.44137438
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.61071354
3IGF1R_20145208_ChIP-Seq_DFB_Human2.80272770
4AR_21572438_ChIP-Seq_LNCaP_Human2.60618631
5CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.47678203
6VDR_22108803_ChIP-Seq_LS180_Human2.43676250
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.32291836
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.19986202
9* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.12650018
10REST_21632747_ChIP-Seq_MESCs_Mouse2.12207831
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.11828356
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.10968788
13EZH2_22144423_ChIP-Seq_EOC_Human11.0972922
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.97308485
15* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95880466
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.95720317
17JARID2_20064375_ChIP-Seq_MESCs_Mouse1.93072517
18EZH2_27304074_Chip-Seq_ESCs_Mouse1.92658146
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.84963875
20SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.84711010
21DROSHA_22980978_ChIP-Seq_HELA_Human1.82354211
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.77853885
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75536308
24PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69065415
25RNF2_27304074_Chip-Seq_NSC_Mouse1.65307017
26ZNF274_21170338_ChIP-Seq_K562_Hela1.61217222
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.60520675
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.60037526
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58821479
30PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57754339
31REST_18959480_ChIP-ChIP_MESCs_Mouse1.57735691
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.57121034
33* P300_19829295_ChIP-Seq_ESCs_Human1.54771980
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.52881197
35POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.52380606
36TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52380606
37E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.48596571
38SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47725571
39PRDM14_20953172_ChIP-Seq_ESCs_Human1.46511857
40SMAD4_21799915_ChIP-Seq_A2780_Human1.46081414
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.44580942
42MTF2_20144788_ChIP-Seq_MESCs_Mouse1.43530185
43SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42096286
44SUZ12_27294783_Chip-Seq_ESCs_Mouse1.38745457
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.38731638
46RNF2_18974828_ChIP-Seq_MESCs_Mouse1.37986345
47EZH2_18974828_ChIP-Seq_MESCs_Mouse1.37986345
48SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.37680332
49KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.37174773
50STAT3_23295773_ChIP-Seq_U87_Human1.35070332
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.30728617
52PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.27852947
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26664952
54BCAT_22108803_ChIP-Seq_LS180_Human1.25655580
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20557071
56AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20306196
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18731931
58CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16946571
59OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14403027
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.11857406
61SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11709668
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10700940
63TCF4_23295773_ChIP-Seq_U87_Human1.10515837
64CBP_20019798_ChIP-Seq_JUKART_Human1.10157143
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10157143
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.07260389
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06711531
68SMAD3_21741376_ChIP-Seq_ESCs_Human1.03296266
69TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03067959
70P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02508142
71SMAD4_21741376_ChIP-Seq_HESCs_Human1.00922267
72ER_23166858_ChIP-Seq_MCF-7_Human0.98591466
73TCF4_22108803_ChIP-Seq_LS180_Human0.97386431
74UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94534474
75KDM2B_26808549_Chip-Seq_REH_Human0.91408735
76RING1B_27294783_Chip-Seq_ESCs_Mouse0.91164120
77RUNX2_22187159_ChIP-Seq_PCA_Human0.91029494
78SOX2_21211035_ChIP-Seq_LN229_Gbm0.90123772
79AR_25329375_ChIP-Seq_VCAP_Human0.89120103
80FLI1_21867929_ChIP-Seq_TH2_Mouse0.88975002
81RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88521332
82TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.88253046
83AR_19668381_ChIP-Seq_PC3_Human0.87687225
84TP53_22573176_ChIP-Seq_HFKS_Human0.87613995
85TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.87016121
86SMAD4_21741376_ChIP-Seq_EPCs_Human0.86135948
87FUS_26573619_Chip-Seq_HEK293_Human0.84764635
88SRY_22984422_ChIP-ChIP_TESTIS_Rat0.83555119
89ARNT_22903824_ChIP-Seq_MCF-7_Human0.83016805
90RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.82730522
91IKZF1_21737484_ChIP-ChIP_HCT116_Human0.82457252
92NR3C1_21868756_ChIP-Seq_MCF10A_Human0.82414197
93JUN_21703547_ChIP-Seq_K562_Human0.82192724
94TAF15_26573619_Chip-Seq_HEK293_Human0.82028286
95KLF5_20875108_ChIP-Seq_MESCs_Mouse0.79804942
96TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.78652154
97LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78561835
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.77433419
99NCOR_22424771_ChIP-Seq_293T_Human0.77056290
100ETV2_25802403_ChIP-Seq_MESCs_Mouse0.77038556

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization4.04177861
2MP0003787_abnormal_imprinting3.45226557
3MP0001984_abnormal_olfaction3.42503651
4MP0005645_abnormal_hypothalamus_physiol3.36647747
5MP0004859_abnormal_synaptic_plasticity3.13032284
6MP0000778_abnormal_nervous_system2.96253286
7MP0004133_heterotaxia2.74346201
8MP0003646_muscle_fatigue2.70662337
9MP0005423_abnormal_somatic_nervous2.52764647
10MP0006276_abnormal_autonomic_nervous2.43740778
11MP0001440_abnormal_grooming_behavior2.38103124
12MP0002557_abnormal_social/conspecific_i2.32652731
13MP0003879_abnormal_hair_cell2.30417973
14MP0002735_abnormal_chemical_nociception2.23729218
15MP0002160_abnormal_reproductive_system2.23619859
16MP0002572_abnormal_emotion/affect_behav2.23460976
17MP0005394_taste/olfaction_phenotype2.22738055
18MP0005499_abnormal_olfactory_system2.22738055
19MP0002067_abnormal_sensory_capabilities2.12369689
20MP0002063_abnormal_learning/memory/cond2.09587521
21MP0004270_analgesia2.09354995
22MP0005551_abnormal_eye_electrophysiolog2.07419106
23MP0001919_abnormal_reproductive_system2.06117194
24MP0004142_abnormal_muscle_tone2.05185891
25MP0003635_abnormal_synaptic_transmissio2.05169258
26MP0003122_maternal_imprinting1.94895781
27MP0002138_abnormal_hepatobiliary_system1.94444591
28MP0003121_genomic_imprinting1.90587089
29MP0002184_abnormal_innervation1.87045278
30MP0010386_abnormal_urinary_bladder1.83582746
31MP0001486_abnormal_startle_reflex1.76715400
32MP0002272_abnormal_nervous_system1.74584967
33MP0009745_abnormal_behavioral_response1.66177883
34MP0002822_catalepsy1.65649004
35MP0002734_abnormal_mechanical_nocicepti1.64895337
36MP0003880_abnormal_central_pattern1.60697885
37MP0000631_abnormal_neuroendocrine_gland1.51628402
38MP0003878_abnormal_ear_physiology1.50580509
39MP0005377_hearing/vestibular/ear_phenot1.50580509
40MP0002064_seizures1.47667495
41MP0002882_abnormal_neuron_morphology1.47135740
42MP0008872_abnormal_physiological_respon1.44122749
43MP0008877_abnormal_DNA_methylation1.43783767
44MP0000955_abnormal_spinal_cord1.42485051
45MP0006292_abnormal_olfactory_placode1.40394698
46MP0005386_behavior/neurological_phenoty1.40364490
47MP0004924_abnormal_behavior1.40364490
48MP0005647_abnormal_sex_gland1.39314113
49MP0001970_abnormal_pain_threshold1.36776255
50MP0003045_fibrosis1.35882243
51MP0009780_abnormal_chondrocyte_physiolo1.34867345
52MP0004043_abnormal_pH_regulation1.32419770
53MP0001968_abnormal_touch/_nociception1.31984923
54MP0005389_reproductive_system_phenotype1.31575048
55MP0009046_muscle_twitch1.19719281
56MP0002733_abnormal_thermal_nociception1.18880285
57MP0001963_abnormal_hearing_physiology1.17141502
58MP0004742_abnormal_vestibular_system1.16278486
59MP0004811_abnormal_neuron_physiology1.15966080
60MP0001188_hyperpigmentation1.12685435
61MP0002752_abnormal_somatic_nervous1.11911382
62MP0002152_abnormal_brain_morphology1.07977832
63MP0008789_abnormal_olfactory_epithelium1.07021889
64MP0000230_abnormal_systemic_arterial1.06310356
65MP0002736_abnormal_nociception_after1.05613227
66MP0004145_abnormal_muscle_electrophysio1.04155300
67MP0001485_abnormal_pinna_reflex1.02884296
68MP0001501_abnormal_sleep_pattern1.01392804
69MP0004130_abnormal_muscle_cell1.00524312
70MP0003861_abnormal_nervous_system0.98460548
71MP0005409_darkened_coat_color0.98243889
72MP0002066_abnormal_motor_capabilities/c0.97363716
73MP0004885_abnormal_endolymph0.95569184
74MP0005195_abnormal_posterior_eye0.94735919
75MP0001663_abnormal_digestive_system0.92933041
76MP0005248_abnormal_Harderian_gland0.91418163
77MP0005448_abnormal_energy_balance0.90121894
78MP0001905_abnormal_dopamine_level0.89883460
79MP0002069_abnormal_eating/drinking_beha0.86786521
80MP0003938_abnormal_ear_development0.85916972
81MP0001764_abnormal_homeostasis0.83419917
82MP0005253_abnormal_eye_physiology0.82281308
83MP0000026_abnormal_inner_ear0.82141401
84MP0001293_anophthalmia0.81316762
85MP0003937_abnormal_limbs/digits/tail_de0.78459470
86MP0004233_abnormal_muscle_weight0.77369653
87MP0002693_abnormal_pancreas_physiology0.71892891
88MP0002095_abnormal_skin_pigmentation0.70431007
89MP0003137_abnormal_impulse_conducting0.69983874
90MP0003868_abnormal_feces_composition0.69983448
91MP0001542_abnormal_bone_strength0.68122747
92MP0003119_abnormal_digestive_system0.67884175
93MP0005381_digestive/alimentary_phenotyp0.67762361
94MP0005646_abnormal_pituitary_gland0.67000243
95MP0006072_abnormal_retinal_apoptosis0.66564962
96MP0002139_abnormal_hepatobiliary_system0.65005343
97MP0000358_abnormal_cell_content/0.64267501
98MP0009379_abnormal_foot_pigmentation0.64212110
99MP0002229_neurodegeneration0.61165798
100MP0003698_abnormal_male_reproductive0.58771932

Predicted human phenotypes

RankGene SetZ-score
1Limb dystonia (HP:0002451)6.45842093
2Pancreatic islet-cell hyperplasia (HP:0004510)6.06774386
3J-shaped sella turcica (HP:0002680)4.98106785
4Hyperinsulinemic hypoglycemia (HP:0000825)4.82839420
5Large for gestational age (HP:0001520)4.21452688
6Nephronophthisis (HP:0000090)3.89160692
7Prominent metopic ridge (HP:0005487)3.85394003
8Genetic anticipation (HP:0003743)3.79988379
9Insulin-resistant diabetes mellitus (HP:0000831)3.76329194
10Myokymia (HP:0002411)3.69500925
11Thoracic kyphosis (HP:0002942)3.64006633
12Attenuation of retinal blood vessels (HP:0007843)3.57653301
13Abnormality of the metopic suture (HP:0005556)3.48787553
14Volvulus (HP:0002580)3.30505158
15Abnormality of the lumbar spine (HP:0100712)3.24038954
16Abnormality of endocrine pancreas physiology (HP:0012093)3.23149675
17Abnormality of the pancreatic islet cells (HP:0006476)3.23149675
18Polyphagia (HP:0002591)3.02112127
19Palpebral edema (HP:0100540)3.00737283
20Epileptic encephalopathy (HP:0200134)2.95669271
21Drooling (HP:0002307)2.90981175
22Abnormality of the renal medulla (HP:0100957)2.89270496
23Agitation (HP:0000713)2.88227152
24Progressive cerebellar ataxia (HP:0002073)2.87730762
25Excessive salivation (HP:0003781)2.74926947
26Broad-based gait (HP:0002136)2.72789635
27Partial agenesis of the corpus callosum (HP:0001338)2.70853795
28Chronic hepatic failure (HP:0100626)2.68916714
29Protruding tongue (HP:0010808)2.68848246
30Focal motor seizures (HP:0011153)2.66779842
31Pachygyria (HP:0001302)2.63570301
32High anterior hairline (HP:0009890)2.60839530
33Pendular nystagmus (HP:0012043)2.60334585
34Bulbous nose (HP:0000414)2.59983306
35Torticollis (HP:0000473)2.58847917
36Hyperventilation (HP:0002883)2.54041400
37Hypsarrhythmia (HP:0002521)2.52975570
38Gait imbalance (HP:0002141)2.48929344
39Molar tooth sign on MRI (HP:0002419)2.47128453
40Abnormality of midbrain morphology (HP:0002418)2.47128453
41EEG with generalized epileptiform discharges (HP:0011198)2.44891169
42Hyperglycemia (HP:0003074)2.42146666
43Deformed sella turcica (HP:0002681)2.40587209
44Focal seizures (HP:0007359)2.39172707
45Epileptiform EEG discharges (HP:0011182)2.38210882
46Shawl scrotum (HP:0000049)2.33797307
47Prolonged QT interval (HP:0001657)2.32876594
48Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.31443595
49Ketoacidosis (HP:0001993)2.29338103
50Lissencephaly (HP:0001339)2.28484149
51Fetal akinesia sequence (HP:0001989)2.22089988
52Tented upper lip vermilion (HP:0010804)2.17759723
53Abnormality of salivation (HP:0100755)2.16229023
54Abnormality of the thoracic spine (HP:0100711)2.16033301
55Hypoplastic ischia (HP:0003175)2.14237426
56Pancreatic cysts (HP:0001737)2.12526492
57Megalocornea (HP:0000485)2.11719662
58True hermaphroditism (HP:0010459)2.11369547
59Beaking of vertebral bodies (HP:0004568)2.05315055
60Hemiparesis (HP:0001269)2.04504676
61Bell-shaped thorax (HP:0001591)2.03543069
62Abnormality of the sella turcica (HP:0002679)2.03316464
63Periorbital edema (HP:0100539)2.03236771
64Inappropriate behavior (HP:0000719)2.03130564
65Insulin resistance (HP:0000855)1.99167203
66Synostosis of carpal bones (HP:0005048)1.96656587
67Amyotrophic lateral sclerosis (HP:0007354)1.95303505
68Febrile seizures (HP:0002373)1.94843264
69Hypoplasia of the odontoid process (HP:0003311)1.93814511
70Ketosis (HP:0001946)1.91054215
71Abnormal ciliary motility (HP:0012262)1.90992226
72Facial edema (HP:0000282)1.90860428
73Absent rod-and cone-mediated responses on ERG (HP:0007688)1.88795503
74Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.88515659
75Absent epiphyses (HP:0010577)1.88515659
76Stage 5 chronic kidney disease (HP:0003774)1.88322505
77Mutism (HP:0002300)1.86344990
78Akinesia (HP:0002304)1.85712710
79Abnormality of the ischium (HP:0003174)1.83859856
80Abnormal pancreas size (HP:0012094)1.83647327
81Morphological abnormality of the pyramidal tract (HP:0002062)1.82410308
82Optic disc pallor (HP:0000543)1.80969651
83Urethral obstruction (HP:0000796)1.79650139
84Generalized aminoaciduria (HP:0002909)1.76833820
85Abnormality of the odontoid process (HP:0003310)1.76134294
86Dyskinesia (HP:0100660)1.73433613
87Abnormality of binocular vision (HP:0011514)1.73174775
88Diplopia (HP:0000651)1.73174775
89Tubulointerstitial nephritis (HP:0001970)1.72188734
90Exotropia (HP:0000577)1.71715789
91Intellectual disability, severe (HP:0010864)1.71305469
92Sclerocornea (HP:0000647)1.70762407
93Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.70621416
94Acute necrotizing encephalopathy (HP:0006965)1.68865353
95Narrow forehead (HP:0000341)1.68136282
96Cystic liver disease (HP:0006706)1.67934728
97Mixed hearing impairment (HP:0000410)1.67363143
98Abdominal situs inversus (HP:0003363)1.67068373
99Abnormality of abdominal situs (HP:0011620)1.67068373
100Glycosuria (HP:0003076)1.66688402

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.95505586
2MAP3K125.26984396
3CASK4.90334860
4MAPK134.29806310
5DDR23.14418819
6CAMKK23.11740262
7PHKG12.92249191
8PHKG22.92249191
9DYRK22.86153927
10CDK192.00042240
11MAP3K111.88403326
12TLK11.86203817
13CAMKK11.72834708
14MAPKAPK31.65333603
15MAP4K21.61907016
16CAMK1D1.39632153
17ADRBK11.36300389
18MAP2K41.36014665
19MINK11.33170903
20DYRK1A1.27219724
21WNK31.25629243
22NTRK21.19303201
23PRKCH1.17424404
24MST41.15701387
25NTRK11.14506445
26FRK1.12714426
27DAPK11.03916176
28CAMK1G0.98843016
29PINK10.98585987
30LIMK10.96380883
31ABL20.95989302
32BLK0.95730760
33DYRK30.94527912
34DAPK20.92408252
35PKN10.92263196
36CSNK1G20.91705440
37BCR0.89677087
38PRPF4B0.88819439
39RIPK10.88183714
40ALK0.86858672
41MAP3K50.86168408
42MAP3K40.85839836
43CSNK1G30.84849892
44CSNK1G10.82019818
45CAMK2D0.81680603
46MAP2K70.80540708
47MAP4K10.78042443
48CAMK40.73538493
49BCKDK0.70677398
50TYRO30.67423981
51PRKCI0.66943978
52CDK140.65159800
53CSNK1A1L0.63843231
54SYK0.61233490
55MARK20.59775561
56TAOK20.59159703
57CAMK2A0.58337504
58MAPK120.57790693
59PIK3CA0.56911797
60CAMK10.56683925
61EPHA40.56133191
62CDK11A0.55007461
63CSF1R0.54312435
64CDK150.52672266
65PAK30.50904604
66NTRK30.49625177
67CDK50.48872917
68CDK180.47382733
69PLK20.45845568
70CHEK20.45814329
71GRK70.44908247
72SGK2230.44497977
73SGK4940.44497977
74PRKCG0.43686022
75ERBB20.43549217
76EIF2AK20.43497122
77SCYL20.40112709
78GRK10.38918177
79PRKCE0.38908380
80FYN0.37907556
81PIK3CG0.37202087
82SGK10.36590578
83TGFBR20.35179118
84CSNK1D0.34399503
85PRKACA0.33638766
86WNK40.33117361
87AURKA0.32986169
88EPHB20.30757183
89ADRBK20.29862551
90RPS6KB10.29387886
91PRKG10.28016383
92ILK0.26767489
93OXSR10.26753286
94SGK20.25616229
95LMTK20.25254811
96MATK0.25224968
97MAP3K90.25003808
98PRKCA0.24488877
99SIK20.24256020
100INSRR0.23733052

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047445.27587607
2Nicotine addiction_Homo sapiens_hsa050333.25721422
3Type II diabetes mellitus_Homo sapiens_hsa049303.22718964
4Taste transduction_Homo sapiens_hsa047422.20473690
5GABAergic synapse_Homo sapiens_hsa047272.18189636
6Circadian entrainment_Homo sapiens_hsa047132.15817111
7Insulin secretion_Homo sapiens_hsa049112.15692918
8Cardiac muscle contraction_Homo sapiens_hsa042602.07074679
9Calcium signaling pathway_Homo sapiens_hsa040202.07027006
10Morphine addiction_Homo sapiens_hsa050322.06584752
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.01566017
12Circadian rhythm_Homo sapiens_hsa047102.00544628
13Axon guidance_Homo sapiens_hsa043601.99511776
14Dopaminergic synapse_Homo sapiens_hsa047281.97145271
15Glutamatergic synapse_Homo sapiens_hsa047241.90131853
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.73238732
17Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.70799141
18Amphetamine addiction_Homo sapiens_hsa050311.70414816
19Nitrogen metabolism_Homo sapiens_hsa009101.67194526
20Salivary secretion_Homo sapiens_hsa049701.66769653
21Olfactory transduction_Homo sapiens_hsa047401.55734465
22Dilated cardiomyopathy_Homo sapiens_hsa054141.55473541
23Cholinergic synapse_Homo sapiens_hsa047251.49856693
24Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.48582354
25Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.48270651
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47230835
27Oxytocin signaling pathway_Homo sapiens_hsa049211.37864181
28Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.34793214
29Synaptic vesicle cycle_Homo sapiens_hsa047211.25799025
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.24163345
31Parkinsons disease_Homo sapiens_hsa050121.24016515
32Serotonergic synapse_Homo sapiens_hsa047261.18873738
33Hedgehog signaling pathway_Homo sapiens_hsa043401.18143199
34Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.15664476
35Cocaine addiction_Homo sapiens_hsa050301.12497533
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08829021
37Gastric acid secretion_Homo sapiens_hsa049711.07619837
38Oocyte meiosis_Homo sapiens_hsa041141.05780309
39Renin secretion_Homo sapiens_hsa049241.05223298
40Oxidative phosphorylation_Homo sapiens_hsa001901.05112289
41Alcoholism_Homo sapiens_hsa050341.00307764
42Alzheimers disease_Homo sapiens_hsa050100.99508448
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.96725911
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93763031
45Aldosterone synthesis and secretion_Homo sapiens_hsa049250.93184828
46Linoleic acid metabolism_Homo sapiens_hsa005910.92826420
47RNA polymerase_Homo sapiens_hsa030200.88084325
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86977188
49Basal cell carcinoma_Homo sapiens_hsa052170.86814476
50MAPK signaling pathway_Homo sapiens_hsa040100.85619334
51Long-term potentiation_Homo sapiens_hsa047200.83020643
52Lysine degradation_Homo sapiens_hsa003100.82316133
53Arginine biosynthesis_Homo sapiens_hsa002200.80819727
54Fatty acid biosynthesis_Homo sapiens_hsa000610.80076666
55ErbB signaling pathway_Homo sapiens_hsa040120.79323601
56Regulation of autophagy_Homo sapiens_hsa041400.79133179
57Glycerolipid metabolism_Homo sapiens_hsa005610.78950544
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.78622731
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77067872
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76399969
61GnRH signaling pathway_Homo sapiens_hsa049120.75999638
62Wnt signaling pathway_Homo sapiens_hsa043100.75317564
63Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73461997
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69809122
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69218574
66Butanoate metabolism_Homo sapiens_hsa006500.68442622
67Pancreatic secretion_Homo sapiens_hsa049720.64992988
68cAMP signaling pathway_Homo sapiens_hsa040240.63385926
69Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61896419
70Hippo signaling pathway_Homo sapiens_hsa043900.61342047
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61139554
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.59246666
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.59207930
74Gap junction_Homo sapiens_hsa045400.55597848
75Systemic lupus erythematosus_Homo sapiens_hsa053220.55582959
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55235377
77Huntingtons disease_Homo sapiens_hsa050160.51968213
78Long-term depression_Homo sapiens_hsa047300.48748596
79Mineral absorption_Homo sapiens_hsa049780.48721704
80Fat digestion and absorption_Homo sapiens_hsa049750.46681917
81Chemical carcinogenesis_Homo sapiens_hsa052040.46341501
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41912459
83Ras signaling pathway_Homo sapiens_hsa040140.41831438
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.41655299
85Endocytosis_Homo sapiens_hsa041440.40760037
86Ovarian steroidogenesis_Homo sapiens_hsa049130.40507508
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37916690
88Rap1 signaling pathway_Homo sapiens_hsa040150.36509939
89Phagosome_Homo sapiens_hsa041450.34431243
90Platelet activation_Homo sapiens_hsa046110.34428649
91N-Glycan biosynthesis_Homo sapiens_hsa005100.34255052
92ABC transporters_Homo sapiens_hsa020100.32917242
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.32906400
94Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.30957446
95Tight junction_Homo sapiens_hsa045300.29356496
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.28786151
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28445854
98Fatty acid metabolism_Homo sapiens_hsa012120.25034342
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24910941
100Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.24088062

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »