Rank | Gene Set | Z-score |
---|---|---|
1 | behavioral response to nicotine (GO:0035095) | 4.40401574 |
2 | regulation of hippo signaling (GO:0035330) | 3.73708502 |
3 | fucose catabolic process (GO:0019317) | 3.41037098 |
4 | L-fucose metabolic process (GO:0042354) | 3.41037098 |
5 | L-fucose catabolic process (GO:0042355) | 3.41037098 |
6 | axon extension involved in axon guidance (GO:0048846) | 3.23727352 |
7 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.23727352 |
8 | nucleobase catabolic process (GO:0046113) | 3.09168368 |
9 | neural tube formation (GO:0001841) | 2.99239036 |
10 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.95611495 |
11 | gamma-aminobutyric acid transport (GO:0015812) | 2.95238361 |
12 | nephron epithelium morphogenesis (GO:0072088) | 2.93939909 |
13 | nephron tubule morphogenesis (GO:0072078) | 2.93939909 |
14 | regulation of gene silencing by RNA (GO:0060966) | 2.91827886 |
15 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.91827886 |
16 | regulation of gene silencing by miRNA (GO:0060964) | 2.91827886 |
17 | kidney morphogenesis (GO:0060993) | 2.90081258 |
18 | postsynaptic membrane organization (GO:0001941) | 2.89905505 |
19 | presynaptic membrane assembly (GO:0097105) | 2.86322592 |
20 | renal tubule morphogenesis (GO:0061333) | 2.84558461 |
21 | tryptophan catabolic process (GO:0006569) | 2.82832165 |
22 | indole-containing compound catabolic process (GO:0042436) | 2.82832165 |
23 | indolalkylamine catabolic process (GO:0046218) | 2.82832165 |
24 | regulation of axon guidance (GO:1902667) | 2.81830938 |
25 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.81726604 |
26 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.79415054 |
27 | response to pheromone (GO:0019236) | 2.78325006 |
28 | nonmotile primary cilium assembly (GO:0035058) | 2.74249378 |
29 | ganglion development (GO:0061548) | 2.74069328 |
30 | dermatan sulfate biosynthetic process (GO:0030208) | 2.71703821 |
31 | pericardium development (GO:0060039) | 2.71620604 |
32 | indolalkylamine metabolic process (GO:0006586) | 2.68519559 |
33 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.66456061 |
34 | cAMP catabolic process (GO:0006198) | 2.66145302 |
35 | establishment of nucleus localization (GO:0040023) | 2.65440394 |
36 | dendrite morphogenesis (GO:0048813) | 2.64537057 |
37 | kynurenine metabolic process (GO:0070189) | 2.61460218 |
38 | neuronal stem cell maintenance (GO:0097150) | 2.60997930 |
39 | limb development (GO:0060173) | 2.60972822 |
40 | appendage development (GO:0048736) | 2.60972822 |
41 | neuronal action potential (GO:0019228) | 2.56999942 |
42 | retina layer formation (GO:0010842) | 2.56515506 |
43 | limb bud formation (GO:0060174) | 2.56111560 |
44 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.53533313 |
45 | fibroblast migration (GO:0010761) | 2.53161488 |
46 | nucleus localization (GO:0051647) | 2.51803447 |
47 | tryptophan metabolic process (GO:0006568) | 2.50526320 |
48 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 2.49362709 |
49 | cyclic nucleotide catabolic process (GO:0009214) | 2.49149356 |
50 | presynaptic membrane organization (GO:0097090) | 2.49006116 |
51 | negative chemotaxis (GO:0050919) | 2.48863083 |
52 | semaphorin-plexin signaling pathway (GO:0071526) | 2.48785349 |
53 | head development (GO:0060322) | 2.48326618 |
54 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.47787250 |
55 | retinal ganglion cell axon guidance (GO:0031290) | 2.47654509 |
56 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.47640831 |
57 | regulation of pigment cell differentiation (GO:0050932) | 2.47338473 |
58 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.45988693 |
59 | behavioral response to ethanol (GO:0048149) | 2.45786756 |
60 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.45735245 |
61 | cardiac myofibril assembly (GO:0055003) | 2.43860818 |
62 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.40158204 |
63 | primary amino compound metabolic process (GO:1901160) | 2.38519458 |
64 | negative regulation of axon guidance (GO:1902668) | 2.38194823 |
65 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.37857900 |
66 | axonal fasciculation (GO:0007413) | 2.36628105 |
67 | serotonin metabolic process (GO:0042428) | 2.36424910 |
68 | layer formation in cerebral cortex (GO:0021819) | 2.35859206 |
69 | sulfation (GO:0051923) | 2.34659441 |
70 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.33066054 |
71 | urinary tract smooth muscle contraction (GO:0014848) | 2.32353348 |
72 | artery development (GO:0060840) | 2.31925862 |
73 | spinal cord development (GO:0021510) | 2.30741996 |
74 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.30330614 |
75 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.30114224 |
76 | positive regulation of fatty acid oxidation (GO:0046321) | 2.29990124 |
77 | protein K11-linked deubiquitination (GO:0035871) | 2.29091500 |
78 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.28817195 |
79 | indole-containing compound metabolic process (GO:0042430) | 2.28428895 |
80 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.28324018 |
81 | axon extension (GO:0048675) | 2.28260628 |
82 | spinal cord motor neuron differentiation (GO:0021522) | 2.27823699 |
83 | atrial cardiac muscle cell action potential (GO:0086014) | 2.27566487 |
84 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.27436490 |
85 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.27304820 |
86 | dermatan sulfate metabolic process (GO:0030205) | 2.26985328 |
87 | hindbrain development (GO:0030902) | 2.26753267 |
88 | neuron maturation (GO:0042551) | 2.26195880 |
89 | glomerulus development (GO:0032835) | 2.25984844 |
90 | inner ear receptor cell development (GO:0060119) | 2.25572128 |
91 | interkinetic nuclear migration (GO:0022027) | 2.24753604 |
92 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.24558889 |
93 | detection of light stimulus involved in visual perception (GO:0050908) | 2.24558889 |
94 | glutamate receptor signaling pathway (GO:0007215) | 2.24464722 |
95 | membrane depolarization during action potential (GO:0086010) | 2.23308518 |
96 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.23086689 |
97 | heart morphogenesis (GO:0003007) | 2.21965938 |
98 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.21631786 |
99 | negative regulation of Rho protein signal transduction (GO:0035024) | 2.21556596 |
100 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.21279041 |
101 | startle response (GO:0001964) | 2.21083339 |
102 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.20591940 |
103 | photoreceptor cell maintenance (GO:0045494) | 2.20253894 |
104 | smooth muscle contraction (GO:0006939) | 2.19956297 |
105 | inner ear receptor stereocilium organization (GO:0060122) | 2.19727191 |
106 | dendritic spine morphogenesis (GO:0060997) | 2.18858799 |
107 | cilium morphogenesis (GO:0060271) | 2.18611641 |
108 | somite development (GO:0061053) | 2.17754892 |
109 | locomotory exploration behavior (GO:0035641) | 2.17334809 |
110 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.16874664 |
111 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.15544110 |
112 | regulation of protein polyubiquitination (GO:1902914) | 2.14477580 |
113 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.13128957 |
114 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.13091693 |
115 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.12265344 |
116 | lymphangiogenesis (GO:0001946) | 2.12015064 |
117 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.10824442 |
118 | glomerular basement membrane development (GO:0032836) | 2.09914311 |
119 | negative regulation of vascular permeability (GO:0043116) | 2.09637892 |
120 | positive regulation of hormone biosynthetic process (GO:0046886) | 2.09507335 |
121 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.08931621 |
122 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.08776653 |
123 | vocalization behavior (GO:0071625) | 2.08665001 |
124 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.08465162 |
125 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.08096846 |
126 | cell communication by electrical coupling (GO:0010644) | 2.08022677 |
127 | regulation of neuron migration (GO:2001222) | 2.06695751 |
128 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.06248361 |
129 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.06248361 |
130 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.06248361 |
131 | anatomical structure arrangement (GO:0048532) | 2.05918174 |
132 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.05311766 |
133 | neuron recognition (GO:0008038) | 2.04857649 |
134 | hippo signaling (GO:0035329) | 2.04614152 |
135 | myelination in peripheral nervous system (GO:0022011) | 2.04415999 |
136 | peripheral nervous system axon ensheathment (GO:0032292) | 2.04415999 |
137 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.03821897 |
138 | growth hormone receptor signaling pathway (GO:0060396) | 2.02816404 |
139 | paraxial mesoderm development (GO:0048339) | 2.01268941 |
140 | glial cell proliferation (GO:0014009) | 2.00454178 |
141 | coronary vasculature morphogenesis (GO:0060977) | 2.00278893 |
142 | histone H3-K4 trimethylation (GO:0080182) | 1.99764714 |
143 | epithelial cell differentiation involved in kidney development (GO:0035850) | 1.99349171 |
144 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 1.98916180 |
145 | histone H3-K36 demethylation (GO:0070544) | 1.98355786 |
146 | cell adhesion mediated by integrin (GO:0033627) | 1.96667771 |
147 | positive regulation of cellular amide metabolic process (GO:0034250) | 1.96667721 |
148 | innervation (GO:0060384) | 1.96540956 |
149 | gastrulation with mouth forming second (GO:0001702) | 1.96476911 |
150 | myoblast fusion (GO:0007520) | 1.96093832 |
151 | camera-type eye morphogenesis (GO:0048593) | 1.95703615 |
152 | cell migration in hindbrain (GO:0021535) | 1.95599088 |
153 | morphogenesis of an epithelial sheet (GO:0002011) | 1.95000524 |
154 | metanephric nephron tubule development (GO:0072234) | 1.93725435 |
155 | metanephric tubule development (GO:0072170) | 1.93725435 |
156 | macroautophagy (GO:0016236) | 1.92965928 |
157 | cranial nerve structural organization (GO:0021604) | 1.91984003 |
158 | metanephric mesenchyme development (GO:0072075) | 1.91889108 |
159 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 1.91427280 |
160 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 1.90972340 |
161 | myofibril assembly (GO:0030239) | 1.90217175 |
162 | neuron projection extension (GO:1990138) | 1.89869071 |
163 | stress granule assembly (GO:0034063) | 1.89792195 |
164 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 1.89776957 |
165 | metanephric epithelium development (GO:0072207) | 1.89625371 |
166 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 1.89406962 |
167 | cell differentiation involved in kidney development (GO:0061005) | 1.88924191 |
168 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 1.88598003 |
169 | metanephric nephron epithelium development (GO:0072243) | 1.88544453 |
170 | gonadal mesoderm development (GO:0007506) | 1.88360203 |
171 | histone H3-K9 demethylation (GO:0033169) | 1.88343882 |
172 | central nervous system neuron axonogenesis (GO:0021955) | 1.88178801 |
173 | pyrimidine nucleobase catabolic process (GO:0006208) | 1.85602612 |
174 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 1.85192107 |
175 | cell communication involved in cardiac conduction (GO:0086065) | 1.84886556 |
176 | cerebral cortex cell migration (GO:0021795) | 1.84741537 |
177 | polyketide metabolic process (GO:0030638) | 1.84596584 |
178 | doxorubicin metabolic process (GO:0044598) | 1.84596584 |
179 | daunorubicin metabolic process (GO:0044597) | 1.84596584 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.79426760 |
2 | * GBX2_23144817_ChIP-Seq_PC3_Human | 2.98848586 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62902807 |
4 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.22731033 |
5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11976724 |
6 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.97654370 |
7 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.95067193 |
8 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.92771311 |
9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89655288 |
10 | FUS_26573619_Chip-Seq_HEK293_Human | 1.85416773 |
11 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.83772357 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.79637613 |
13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.79637613 |
14 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.78987800 |
15 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.75293935 |
16 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.73891625 |
17 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.73875174 |
18 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.73449372 |
19 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.72766689 |
20 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.71425662 |
21 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.68031413 |
22 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.65304105 |
23 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.65136643 |
24 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.64224803 |
25 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.61648489 |
26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58606407 |
27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.58324745 |
28 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.56664502 |
29 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.54346949 |
30 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.53252193 |
31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.52361594 |
32 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.52033687 |
33 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.51835376 |
34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.51559853 |
35 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.51071190 |
36 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.50182859 |
37 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.47865279 |
38 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.47847053 |
39 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.47220937 |
40 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.44663631 |
41 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.42161816 |
42 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.39822192 |
43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.39174540 |
44 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.39046086 |
45 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.38536173 |
46 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.38062897 |
47 | TP53_16413492_ChIP-PET_HCT116_Human | 1.37440919 |
48 | STAT3_23295773_ChIP-Seq_U87_Human | 1.37269665 |
49 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.37126568 |
50 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.35808178 |
51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35695688 |
52 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.35686794 |
53 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.33448917 |
54 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.31810015 |
55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.30872236 |
56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.30872236 |
57 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.28073840 |
58 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27690721 |
59 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.27690721 |
60 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.27274460 |
61 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.27274460 |
62 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.26656971 |
63 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.26524392 |
64 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.26435326 |
65 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.25797906 |
66 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.25049196 |
67 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.23323215 |
68 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.22144132 |
69 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.21761917 |
70 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.20486627 |
71 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.20482893 |
72 | P300_19829295_ChIP-Seq_ESCs_Human | 1.20059480 |
73 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.19198992 |
74 | * TCF4_22108803_ChIP-Seq_LS180_Human | 1.19183819 |
75 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.19009856 |
76 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.17634433 |
77 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.17312113 |
78 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.17184318 |
79 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.16519148 |
80 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.16272834 |
81 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.14788033 |
82 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.14698389 |
83 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.14628207 |
84 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.14163836 |
85 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.14152839 |
86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14051688 |
87 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.12828363 |
88 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.12486967 |
89 | RXR_22108803_ChIP-Seq_LS180_Human | 1.11484481 |
90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11434196 |
91 | KDM2B_26808549_Chip-Seq_REH_Human | 1.11200648 |
92 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11189396 |
93 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.11035218 |
94 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10691196 |
95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10578110 |
96 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.09803826 |
97 | * AR_19668381_ChIP-Seq_PC3_Human | 1.09730755 |
98 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.08059241 |
99 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.07686028 |
100 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.06422964 |
101 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.05556379 |
102 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.05155844 |
103 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.04746578 |
104 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.04403435 |
105 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03163264 |
106 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02949484 |
107 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.02932111 |
108 | CJUN_26792858_Chip-Seq_BT549_Human | 1.02763547 |
109 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.01968867 |
110 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01586967 |
111 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.00488269 |
112 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99956588 |
113 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.99731331 |
114 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.99009349 |
115 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.98853392 |
116 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97821341 |
117 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.97048020 |
118 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.97008964 |
119 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.96947394 |
120 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95888628 |
121 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.95368586 |
122 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.95349384 |
123 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.94751162 |
124 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.94294198 |
125 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.94204768 |
126 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.94058153 |
127 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 0.93998239 |
128 | TBL1_22424771_ChIP-Seq_293T_Human | 0.93348422 |
129 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.92335348 |
130 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.92161346 |
131 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.91826714 |
132 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.90722637 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 4.42413635 |
2 | MP0008438_abnormal_cutaneous_collagen | 2.86229177 |
3 | MP0004272_abnormal_basement_membrane | 2.52576609 |
4 | MP0000566_synostosis | 2.49065779 |
5 | MP0005248_abnormal_Harderian_gland | 2.48869021 |
6 | MP0004859_abnormal_synaptic_plasticity | 2.43403207 |
7 | MP0005171_absent_coat_pigmentation | 2.39810491 |
8 | MP0005503_abnormal_tendon_morphology | 2.36905372 |
9 | MP0005623_abnormal_meninges_morphology | 2.30110695 |
10 | MP0003136_yellow_coat_color | 2.18699702 |
11 | MP0005257_abnormal_intraocular_pressure | 2.08554134 |
12 | MP0005551_abnormal_eye_electrophysiolog | 2.01690810 |
13 | MP0003195_calcinosis | 1.99497718 |
14 | MP0000778_abnormal_nervous_system | 1.98613086 |
15 | MP0008877_abnormal_DNA_methylation | 1.97941117 |
16 | MP0003045_fibrosis | 1.91486999 |
17 | MP0003385_abnormal_body_wall | 1.88394513 |
18 | MP0004858_abnormal_nervous_system | 1.87961749 |
19 | MP0006292_abnormal_olfactory_placode | 1.87577235 |
20 | MP0000427_abnormal_hair_cycle | 1.77016938 |
21 | MP0003283_abnormal_digestive_organ | 1.74858519 |
22 | MP0010368_abnormal_lymphatic_system | 1.74360462 |
23 | MP0002876_abnormal_thyroid_physiology | 1.64129333 |
24 | MP0003705_abnormal_hypodermis_morpholog | 1.62191825 |
25 | MP0005174_abnormal_tail_pigmentation | 1.60108055 |
26 | MP0003941_abnormal_skin_development | 1.53077634 |
27 | MP0009780_abnormal_chondrocyte_physiolo | 1.49150815 |
28 | MP0004043_abnormal_pH_regulation | 1.49007166 |
29 | MP0001968_abnormal_touch/_nociception | 1.42636396 |
30 | MP0004142_abnormal_muscle_tone | 1.40719891 |
31 | MP0005377_hearing/vestibular/ear_phenot | 1.40370069 |
32 | MP0003878_abnormal_ear_physiology | 1.40370069 |
33 | MP0009745_abnormal_behavioral_response | 1.38600721 |
34 | MP0001299_abnormal_eye_distance/ | 1.37832930 |
35 | MP0000631_abnormal_neuroendocrine_gland | 1.37240334 |
36 | MP0003122_maternal_imprinting | 1.35528714 |
37 | MP0002735_abnormal_chemical_nociception | 1.34651810 |
38 | MP0005167_abnormal_blood-brain_barrier | 1.34517870 |
39 | MP0005253_abnormal_eye_physiology | 1.32496732 |
40 | MP0005275_abnormal_skin_tensile | 1.30560008 |
41 | MP0002108_abnormal_muscle_morphology | 1.29750871 |
42 | MP0002938_white_spotting | 1.28834624 |
43 | MP0004885_abnormal_endolymph | 1.27987359 |
44 | * MP0002272_abnormal_nervous_system | 1.27335205 |
45 | MP0002638_abnormal_pupillary_reflex | 1.25167362 |
46 | MP0002736_abnormal_nociception_after | 1.23870155 |
47 | MP0001485_abnormal_pinna_reflex | 1.23709981 |
48 | MP0001984_abnormal_olfaction | 1.23017789 |
49 | MP0003115_abnormal_respiratory_system | 1.22303789 |
50 | MP0003646_muscle_fatigue | 1.22284811 |
51 | MP0000955_abnormal_spinal_cord | 1.21937345 |
52 | MP0000733_abnormal_muscle_development | 1.21223105 |
53 | MP0002249_abnormal_larynx_morphology | 1.20704349 |
54 | MP0005670_abnormal_white_adipose | 1.20231450 |
55 | MP0003935_abnormal_craniofacial_develop | 1.20220912 |
56 | MP0004084_abnormal_cardiac_muscle | 1.20127299 |
57 | MP0000751_myopathy | 1.17240713 |
58 | MP0010386_abnormal_urinary_bladder | 1.17184874 |
59 | MP0006072_abnormal_retinal_apoptosis | 1.17100450 |
60 | MP0000767_abnormal_smooth_muscle | 1.17095550 |
61 | MP0005386_behavior/neurological_phenoty | 1.16852837 |
62 | MP0004924_abnormal_behavior | 1.16852837 |
63 | MP0001958_emphysema | 1.16777178 |
64 | MP0005076_abnormal_cell_differentiation | 1.16596108 |
65 | MP0006138_congestive_heart_failure | 1.16401310 |
66 | MP0003121_genomic_imprinting | 1.16268357 |
67 | MP0006276_abnormal_autonomic_nervous | 1.15983719 |
68 | MP0005645_abnormal_hypothalamus_physiol | 1.15691900 |
69 | MP0002160_abnormal_reproductive_system | 1.15634885 |
70 | MP0001879_abnormal_lymphatic_vessel | 1.15421871 |
71 | MP0005195_abnormal_posterior_eye | 1.14793681 |
72 | MP0003091_abnormal_cell_migration | 1.14236949 |
73 | MP0001486_abnormal_startle_reflex | 1.13248915 |
74 | MP0001501_abnormal_sleep_pattern | 1.12168826 |
75 | MP0004133_heterotaxia | 1.11855276 |
76 | MP0005187_abnormal_penis_morphology | 1.11399501 |
77 | MP0003632_abnormal_nervous_system | 1.09607151 |
78 | MP0002734_abnormal_mechanical_nocicepti | 1.09575066 |
79 | MP0005595_abnormal_vascular_smooth | 1.07980446 |
80 | MP0003950_abnormal_plasma_membrane | 1.07813779 |
81 | MP0004215_abnormal_myocardial_fiber | 1.07258690 |
82 | MP0003787_abnormal_imprinting | 1.07072277 |
83 | MP0005423_abnormal_somatic_nervous | 1.06805489 |
84 | MP0003890_abnormal_embryonic-extraembry | 1.06670363 |
85 | MP0002168_other_aberrant_phenotype | 1.05989589 |
86 | * MP0002067_abnormal_sensory_capabilities | 1.05842656 |
87 | MP0010678_abnormal_skin_adnexa | 1.05681523 |
88 | MP0000538_abnormal_urinary_bladder | 1.05620490 |
89 | MP0003635_abnormal_synaptic_transmissio | 1.05305386 |
90 | MP0002837_dystrophic_cardiac_calcinosis | 1.04926661 |
91 | MP0000534_abnormal_ureter_morphology | 1.04394435 |
92 | MP0000383_abnormal_hair_follicle | 1.04281228 |
93 | MP0003937_abnormal_limbs/digits/tail_de | 1.03958752 |
94 | MP0003119_abnormal_digestive_system | 1.03898065 |
95 | MP0002254_reproductive_system_inflammat | 1.03473005 |
96 | MP0001986_abnormal_taste_sensitivity | 1.03338235 |
97 | MP0000230_abnormal_systemic_arterial | 1.02674557 |
98 | MP0009384_cardiac_valve_regurgitation | 1.02624816 |
99 | MP0002064_seizures | 1.01738123 |
100 | MP0000516_abnormal_urinary_system | 1.01069752 |
101 | MP0005367_renal/urinary_system_phenotyp | 1.01069752 |
102 | MP0005646_abnormal_pituitary_gland | 1.01025150 |
103 | MP0002557_abnormal_social/conspecific_i | 1.00763715 |
104 | MP0004085_abnormal_heartbeat | 1.00761233 |
105 | MP0002896_abnormal_bone_mineralization | 1.00527370 |
106 | MP0002752_abnormal_somatic_nervous | 1.00238300 |
107 | MP0003690_abnormal_glial_cell | 0.99820989 |
108 | MP0001970_abnormal_pain_threshold | 0.98903554 |
109 | MP0002116_abnormal_craniofacial_bone | 0.98633209 |
110 | MP0001286_abnormal_eye_development | 0.98601079 |
111 | MP0002697_abnormal_eye_size | 0.97733465 |
112 | MP0003755_abnormal_palate_morphology | 0.97038181 |
113 | MP0008775_abnormal_heart_ventricle | 0.95643671 |
114 | * MP0002882_abnormal_neuron_morphology | 0.95622901 |
115 | MP0002063_abnormal_learning/memory/cond | 0.95562622 |
116 | MP0003252_abnormal_bile_duct | 0.94779202 |
117 | MP0002102_abnormal_ear_morphology | 0.93723508 |
118 | MP0002733_abnormal_thermal_nociception | 0.93239846 |
119 | MP0009046_muscle_twitch | 0.92989119 |
120 | MP0002928_abnormal_bile_duct | 0.92808718 |
121 | MP0002184_abnormal_innervation | 0.92470736 |
122 | MP0000026_abnormal_inner_ear | 0.92455498 |
123 | MP0003942_abnormal_urinary_system | 0.91378623 |
124 | MP0005666_abnormal_adipose_tissue | 0.89706699 |
125 | MP0004145_abnormal_muscle_electrophysio | 0.88758202 |
126 | MP0002234_abnormal_pharynx_morphology | 0.88538732 |
127 | MP0000432_abnormal_head_morphology | 0.87686309 |
128 | MP0004270_analgesia | 0.87592950 |
129 | MP0004742_abnormal_vestibular_system | 0.87419941 |
130 | MP0004130_abnormal_muscle_cell | 0.87383314 |
131 | MP0002233_abnormal_nose_morphology | 0.86715356 |
132 | MP0000537_abnormal_urethra_morphology | 0.86502362 |
133 | MP0001324_abnormal_eye_pigmentation | 0.86497977 |
134 | MP0003828_pulmonary_edema | 0.85615360 |
135 | MP0000647_abnormal_sebaceous_gland | 0.83882070 |
136 | MP0005391_vision/eye_phenotype | 0.83868385 |
137 | MP0009250_abnormal_appendicular_skeleto | 0.83684981 |
138 | MP0002925_abnormal_cardiovascular_devel | 0.83213142 |
139 | MP0002972_abnormal_cardiac_muscle | 0.81042764 |
140 | MP0003634_abnormal_glial_cell | 0.79802608 |
141 | MP0005197_abnormal_uvea_morphology | 0.78738749 |
142 | MP0003566_abnormal_cell_adhesion | 0.78632266 |
143 | MP0002572_abnormal_emotion/affect_behav | 0.78629887 |
144 | MP0010630_abnormal_cardiac_muscle | 0.78277658 |
145 | MP0005620_abnormal_muscle_contractility | 0.77933557 |
146 | MP0003861_abnormal_nervous_system | 0.77868129 |
147 | MP0001293_anophthalmia | 0.77237302 |
148 | MP0003279_aneurysm | 0.77227344 |
149 | MP0001177_atelectasis | 0.77218138 |
150 | MP0000049_abnormal_middle_ear | 0.77050182 |
151 | MP0004233_abnormal_muscle_weight | 0.75963268 |
152 | MP0002152_abnormal_brain_morphology | 0.75681300 |
153 | MP0002127_abnormal_cardiovascular_syste | 0.75508589 |
154 | MP0005508_abnormal_skeleton_morphology | 0.74907907 |
155 | MP0000428_abnormal_craniofacial_morphol | 0.74571176 |
156 | MP0002653_abnormal_ependyma_morphology | 0.74275157 |
157 | MP0004185_abnormal_adipocyte_glucose | 0.73882714 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperventilation (HP:0002883) | 4.19408738 |
2 | Pancreatic cysts (HP:0001737) | 3.63996410 |
3 | Abnormality of midbrain morphology (HP:0002418) | 3.48530481 |
4 | Molar tooth sign on MRI (HP:0002419) | 3.48530481 |
5 | Pancreatic fibrosis (HP:0100732) | 3.39241555 |
6 | Protruding tongue (HP:0010808) | 3.25833791 |
7 | Type II lissencephaly (HP:0007260) | 3.18988934 |
8 | Nephronophthisis (HP:0000090) | 3.16524598 |
9 | True hermaphroditism (HP:0010459) | 3.08525009 |
10 | Abnormality of the renal medulla (HP:0100957) | 2.94155764 |
11 | Shallow orbits (HP:0000586) | 2.92024780 |
12 | Congenital stationary night blindness (HP:0007642) | 2.88449981 |
13 | Midline defect of the nose (HP:0004122) | 2.78860743 |
14 | Keratoconus (HP:0000563) | 2.71899065 |
15 | Increased corneal curvature (HP:0100692) | 2.71899065 |
16 | Abnormality of the renal cortex (HP:0011035) | 2.71206105 |
17 | Fair hair (HP:0002286) | 2.70469363 |
18 | Tubular atrophy (HP:0000092) | 2.64117066 |
19 | Inability to walk (HP:0002540) | 2.62466978 |
20 | Gaze-evoked nystagmus (HP:0000640) | 2.61780881 |
21 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.59844550 |
22 | Short 4th metacarpal (HP:0010044) | 2.59844550 |
23 | Broad-based gait (HP:0002136) | 2.59158579 |
24 | Cerebellar dysplasia (HP:0007033) | 2.49125449 |
25 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.49090655 |
26 | Abnormality of alanine metabolism (HP:0010916) | 2.49090655 |
27 | Hyperalaninemia (HP:0003348) | 2.49090655 |
28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.48733488 |
29 | Absent/shortened dynein arms (HP:0200106) | 2.48733488 |
30 | Lissencephaly (HP:0001339) | 2.46139482 |
31 | Lymphangioma (HP:0100764) | 2.45334348 |
32 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.44140647 |
33 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.38756872 |
34 | Cystic liver disease (HP:0006706) | 2.36961235 |
35 | Subacute progressive viral hepatitis (HP:0006572) | 2.36590497 |
36 | Febrile seizures (HP:0002373) | 2.31816435 |
37 | Papillary thyroid carcinoma (HP:0002895) | 2.31067285 |
38 | Hepatoblastoma (HP:0002884) | 2.30700955 |
39 | Partial agenesis of the corpus callosum (HP:0001338) | 2.27097311 |
40 | Preaxial foot polydactyly (HP:0001841) | 2.26720758 |
41 | Broad metatarsal (HP:0001783) | 2.23854125 |
42 | Medial flaring of the eyebrow (HP:0010747) | 2.22316311 |
43 | Optic nerve hypoplasia (HP:0000609) | 2.21599848 |
44 | Bulbous nose (HP:0000414) | 2.21011759 |
45 | Clumsiness (HP:0002312) | 2.19251296 |
46 | Progressive inability to walk (HP:0002505) | 2.18513097 |
47 | Abnormality of the nasal septum (HP:0000419) | 2.11646640 |
48 | Elfin facies (HP:0004428) | 2.10700774 |
49 | Generalized hypopigmentation of hair (HP:0011358) | 2.09092369 |
50 | Abnormality of the 4th metacarpal (HP:0010012) | 2.08897700 |
51 | Hematochezia (HP:0002573) | 2.06896947 |
52 | Cerebral aneurysm (HP:0004944) | 2.04208043 |
53 | Genetic anticipation (HP:0003743) | 2.02788797 |
54 | Patellar aplasia (HP:0006443) | 2.02751155 |
55 | Absent eyebrow (HP:0002223) | 2.02220474 |
56 | Attenuation of retinal blood vessels (HP:0007843) | 2.01938942 |
57 | Abnormality of the labia majora (HP:0012881) | 2.01397009 |
58 | Hemiparesis (HP:0001269) | 2.00565287 |
59 | Decreased circulating renin level (HP:0003351) | 2.00235099 |
60 | Narrow palate (HP:0000189) | 2.00209831 |
61 | Renovascular hypertension (HP:0100817) | 2.00044281 |
62 | Focal seizures (HP:0007359) | 2.00041038 |
63 | Genital tract atresia (HP:0001827) | 1.99127716 |
64 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.98245227 |
65 | Macroorchidism (HP:0000053) | 1.98099109 |
66 | Polydipsia (HP:0001959) | 1.97522750 |
67 | Abnormal drinking behavior (HP:0030082) | 1.97522750 |
68 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.97250138 |
69 | Bell-shaped thorax (HP:0001591) | 1.97175952 |
70 | Gait imbalance (HP:0002141) | 1.96453935 |
71 | Absent frontal sinuses (HP:0002688) | 1.95507318 |
72 | Atrial fibrillation (HP:0005110) | 1.95188533 |
73 | Blue irides (HP:0000635) | 1.93994257 |
74 | Excessive salivation (HP:0003781) | 1.93884345 |
75 | Drooling (HP:0002307) | 1.93884345 |
76 | Short foot (HP:0001773) | 1.90482808 |
77 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.89383329 |
78 | Cutaneous finger syndactyly (HP:0010554) | 1.88832125 |
79 | Vaginal atresia (HP:0000148) | 1.87731809 |
80 | Hypoplastic ischia (HP:0003175) | 1.87606782 |
81 | Skull defect (HP:0001362) | 1.87032066 |
82 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.83173697 |
83 | Action tremor (HP:0002345) | 1.81337995 |
84 | Congenital hepatic fibrosis (HP:0002612) | 1.80822331 |
85 | Bronchomalacia (HP:0002780) | 1.80464179 |
86 | Abolished electroretinogram (ERG) (HP:0000550) | 1.78418174 |
87 | Primary atrial arrhythmia (HP:0001692) | 1.77896878 |
88 | Congenital primary aphakia (HP:0007707) | 1.77385833 |
89 | Bladder diverticulum (HP:0000015) | 1.76574909 |
90 | Birth length less than 3rd percentile (HP:0003561) | 1.75114949 |
91 | Broad ribs (HP:0000885) | 1.74542808 |
92 | Anophthalmia (HP:0000528) | 1.74435294 |
93 | Poor coordination (HP:0002370) | 1.73298733 |
94 | Anencephaly (HP:0002323) | 1.73298076 |
95 | Small hand (HP:0200055) | 1.73193003 |
96 | Hypoplasia of the iris (HP:0007676) | 1.72985618 |
97 | Cupped ear (HP:0000378) | 1.72644878 |
98 | Prominent supraorbital ridges (HP:0000336) | 1.72529895 |
99 | Inappropriate behavior (HP:0000719) | 1.71738694 |
100 | Cortical dysplasia (HP:0002539) | 1.70884629 |
101 | Retinal dysplasia (HP:0007973) | 1.70658352 |
102 | Chronic hepatic failure (HP:0100626) | 1.70627917 |
103 | Nephrogenic diabetes insipidus (HP:0009806) | 1.70455291 |
104 | Macroglossia (HP:0000158) | 1.68437467 |
105 | Aqueductal stenosis (HP:0002410) | 1.68191858 |
106 | Fibular hypoplasia (HP:0003038) | 1.67748543 |
107 | Aortic aneurysm (HP:0004942) | 1.67734841 |
108 | Abnormality of the ischium (HP:0003174) | 1.67308836 |
109 | Labial hypoplasia (HP:0000066) | 1.67283687 |
110 | Oligodactyly (hands) (HP:0001180) | 1.66472795 |
111 | Postaxial hand polydactyly (HP:0001162) | 1.66356553 |
112 | Renal cortical cysts (HP:0000803) | 1.65694438 |
113 | Anterior segment dysgenesis (HP:0007700) | 1.65639370 |
114 | Furrowed tongue (HP:0000221) | 1.65119083 |
115 | Exotropia (HP:0000577) | 1.64615593 |
116 | Postaxial foot polydactyly (HP:0001830) | 1.63945221 |
117 | Sclerocornea (HP:0000647) | 1.63710286 |
118 | Abnormality of the diencephalon (HP:0010662) | 1.63046297 |
119 | Short chin (HP:0000331) | 1.63007494 |
120 | Aneurysm (HP:0002617) | 1.61681863 |
121 | Leiomyosarcoma (HP:0100243) | 1.61563970 |
122 | Uterine leiomyosarcoma (HP:0002891) | 1.61563970 |
123 | Wide anterior fontanel (HP:0000260) | 1.61159720 |
124 | Atonic seizures (HP:0010819) | 1.60650513 |
125 | Congenital sensorineural hearing impairment (HP:0008527) | 1.60465766 |
126 | Prolonged QT interval (HP:0001657) | 1.60443784 |
127 | Arthropathy (HP:0003040) | 1.59869721 |
128 | Renal dysplasia (HP:0000110) | 1.59839251 |
129 | Intellectual disability, moderate (HP:0002342) | 1.59448860 |
130 | Aortic dissection (HP:0002647) | 1.59096795 |
131 | Chorioretinal atrophy (HP:0000533) | 1.58310357 |
132 | Syncope (HP:0001279) | 1.57979212 |
133 | Urethral obstruction (HP:0000796) | 1.57198544 |
134 | Advanced eruption of teeth (HP:0006288) | 1.56498839 |
135 | Heterotopia (HP:0002282) | 1.55816100 |
136 | Germ cell neoplasia (HP:0100728) | 1.55292696 |
137 | Lower limb amyotrophy (HP:0007210) | 1.54932537 |
138 | Follicular hyperkeratosis (HP:0007502) | 1.54616494 |
139 | Trigonocephaly (HP:0000243) | 1.54156134 |
140 | Turricephaly (HP:0000262) | 1.54052620 |
141 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.53310402 |
142 | Arterial tortuosity (HP:0005116) | 1.52729286 |
143 | Supraventricular arrhythmia (HP:0005115) | 1.52218226 |
144 | Cutaneous syndactyly (HP:0012725) | 1.51688877 |
145 | Portal hypertension (HP:0001409) | 1.51420321 |
146 | Aplasia cutis congenita (HP:0001057) | 1.51125078 |
147 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.50339563 |
148 | Progressive cerebellar ataxia (HP:0002073) | 1.50335186 |
149 | Rectal prolapse (HP:0002035) | 1.49460028 |
150 | Supraventricular tachycardia (HP:0004755) | 1.49348025 |
151 | Obsessive-compulsive behavior (HP:0000722) | 1.47077785 |
152 | Insidious onset (HP:0003587) | 1.46726957 |
153 | Termporal pattern (HP:0011008) | 1.46726957 |
154 | Buphthalmos (HP:0000557) | 1.46370213 |
155 | Sudden death (HP:0001699) | 1.46012871 |
156 | Stage 5 chronic kidney disease (HP:0003774) | 1.45792834 |
157 | Coronal craniosynostosis (HP:0004440) | 1.45511743 |
158 | Absent speech (HP:0001344) | 1.45095358 |
159 | Supernumerary ribs (HP:0005815) | 1.44343186 |
160 | Thick nail (HP:0001805) | 1.44287514 |
161 | Pulmonary artery stenosis (HP:0004415) | 1.43852427 |
162 | Abnormality of the pubic bones (HP:0003172) | 1.43676489 |
163 | Mitral valve prolapse (HP:0001634) | 1.43648220 |
164 | Smooth philtrum (HP:0000319) | 1.43614885 |
165 | Disinhibition (HP:0000734) | 1.43045984 |
166 | Premature rupture of membranes (HP:0001788) | 1.42470445 |
167 | Nephritis (HP:0000123) | 1.42442036 |
168 | Vascular tortuosity (HP:0004948) | 1.42219611 |
169 | Pachygyria (HP:0001302) | 1.41208303 |
170 | Enlarged penis (HP:0000040) | 1.41089642 |
171 | Abnormality of the hepatic vasculature (HP:0006707) | 1.41046582 |
172 | Morphological abnormality of the middle ear (HP:0008609) | 1.40988316 |
173 | Hypoplastic labia majora (HP:0000059) | 1.40926727 |
174 | Scapular winging (HP:0003691) | 1.40911380 |
175 | Alopecia of scalp (HP:0002293) | 1.40765766 |
176 | Flat cornea (HP:0007720) | 1.40142931 |
177 | Widely spaced teeth (HP:0000687) | 1.39927045 |
178 | Renal duplication (HP:0000075) | 1.39401960 |
Rank | Gene Set | Z-score |
---|---|---|
1 | LATS1 | 3.77397103 |
2 | CAMK1G | 2.97840770 |
3 | ACVR1B | 2.89967004 |
4 | BMPR1B | 2.81253702 |
5 | CAMK1D | 2.76937296 |
6 | PNCK | 2.61120997 |
7 | INSRR | 2.28334626 |
8 | MARK1 | 2.20981586 |
9 | ADRBK2 | 2.09778398 |
10 | PINK1 | 2.06245540 |
11 | SIK1 | 2.01046696 |
12 | NTRK3 | 2.00021244 |
13 | SIK2 | 1.98709450 |
14 | WNK3 | 1.85415851 |
15 | PDGFRA | 1.84788167 |
16 | TNIK | 1.74572094 |
17 | PRKD3 | 1.66701042 |
18 | CDK12 | 1.63228336 |
19 | STK39 | 1.61400447 |
20 | GRK1 | 1.57218164 |
21 | SGK2 | 1.54085123 |
22 | DMPK | 1.52935999 |
23 | STK38 | 1.41848833 |
24 | ICK | 1.41007518 |
25 | EPHB2 | 1.39333882 |
26 | LATS2 | 1.36867637 |
27 | TGFBR1 | 1.35980767 |
28 | SGK3 | 1.35890529 |
29 | RIPK1 | 1.32863798 |
30 | STK38L | 1.29967868 |
31 | BRD4 | 1.28350108 |
32 | OXSR1 | 1.25317216 |
33 | ADRBK1 | 1.24202657 |
34 | MAP3K4 | 1.23567772 |
35 | WNK1 | 1.20085362 |
36 | NUAK1 | 1.18395067 |
37 | ERBB3 | 1.14703735 |
38 | EPHA4 | 1.14570929 |
39 | TAOK3 | 1.11960617 |
40 | FGFR2 | 1.11665473 |
41 | FER | 1.11485264 |
42 | EPHA3 | 1.08764039 |
43 | NTRK2 | 1.07181131 |
44 | PDGFRB | 1.05159384 |
45 | PTK6 | 1.04798558 |
46 | TGFBR2 | 1.03958808 |
47 | SGK223 | 1.01894527 |
48 | SGK494 | 1.01894527 |
49 | STK3 | 0.99629577 |
50 | PAK6 | 0.97849908 |
51 | TYRO3 | 0.96102327 |
52 | MAPK13 | 0.93511298 |
53 | PRPF4B | 0.92965250 |
54 | MAPK15 | 0.91003346 |
55 | TTN | 0.89849056 |
56 | LMTK2 | 0.87233464 |
57 | DYRK2 | 0.86869893 |
58 | ZAK | 0.86462837 |
59 | FRK | 0.85746018 |
60 | PHKG1 | 0.85487504 |
61 | PHKG2 | 0.85487504 |
62 | BRSK2 | 0.85284100 |
63 | PTK2B | 0.84891607 |
64 | SGK1 | 0.84831473 |
65 | CAMK4 | 0.84815669 |
66 | NLK | 0.84171997 |
67 | KSR1 | 0.83823440 |
68 | DDR2 | 0.83580311 |
69 | ERBB2 | 0.83376384 |
70 | PRKAA2 | 0.83330072 |
71 | TIE1 | 0.83244029 |
72 | CSNK1A1L | 0.83051554 |
73 | CASK | 0.82707747 |
74 | CAMKK2 | 0.82673532 |
75 | TLK1 | 0.82083262 |
76 | PRKCG | 0.81865696 |
77 | PDK3 | 0.80594050 |
78 | PDK4 | 0.80594050 |
79 | AKT3 | 0.80356799 |
80 | MARK3 | 0.80271635 |
81 | BCR | 0.79084909 |
82 | CDC42BPA | 0.77292876 |
83 | BMX | 0.76906883 |
84 | MARK2 | 0.76422962 |
85 | PDK2 | 0.75291707 |
86 | NEK6 | 0.75111407 |
87 | PTK2 | 0.74770292 |
88 | SIK3 | 0.74585382 |
89 | CAMKK1 | 0.73444621 |
90 | RET | 0.72547329 |
91 | PKN1 | 0.72020456 |
92 | DAPK2 | 0.71581111 |
93 | JAK1 | 0.71570621 |
94 | MTOR | 0.70612067 |
95 | PRKAA1 | 0.69817186 |
96 | PIK3CA | 0.67894256 |
97 | MKNK2 | 0.66892665 |
98 | CHUK | 0.65564163 |
99 | MAP3K7 | 0.65469432 |
100 | ERBB4 | 0.63527311 |
101 | STK11 | 0.63391229 |
102 | TRPM7 | 0.62627030 |
103 | MET | 0.61804330 |
104 | PKN2 | 0.60841640 |
105 | WNK4 | 0.58186677 |
106 | MAP2K4 | 0.58046127 |
107 | PLK2 | 0.56780601 |
108 | ROCK1 | 0.56108963 |
109 | EIF2AK2 | 0.55689414 |
110 | FGFR3 | 0.55099993 |
111 | MAP3K6 | 0.53892990 |
112 | MUSK | 0.53766092 |
113 | MELK | 0.53235141 |
114 | PRKCE | 0.52746815 |
115 | IRAK1 | 0.51926926 |
116 | OBSCN | 0.51718889 |
117 | MAP2K1 | 0.51615310 |
118 | PRKCH | 0.50121031 |
119 | MAP2K7 | 0.48900701 |
120 | CAMK2A | 0.48856106 |
121 | MAPK10 | 0.48552508 |
122 | CSNK1G2 | 0.48397717 |
123 | PRKCZ | 0.48159493 |
124 | NEK2 | 0.45923863 |
125 | CSNK1D | 0.45853542 |
126 | PAK3 | 0.45821369 |
127 | DYRK1A | 0.45010553 |
128 | GSK3A | 0.44968001 |
129 | CAMK1 | 0.44883141 |
130 | CDK9 | 0.44835189 |
131 | RPS6KA6 | 0.42755490 |
132 | MAP4K2 | 0.42737104 |
133 | CDK5 | 0.42409079 |
134 | PIK3CG | 0.42132158 |
135 | CSNK1G1 | 0.42058522 |
136 | FGFR1 | 0.42029022 |
137 | PRKD1 | 0.41512249 |
138 | PRKG1 | 0.38455080 |
139 | MAPKAPK5 | 0.36000110 |
140 | MAP3K2 | 0.32703759 |
Rank | Gene Set | Z-score |
---|---|---|
1 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.00561423 |
2 | Phototransduction_Homo sapiens_hsa04744 | 1.96778218 |
3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.93224168 |
4 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.79106296 |
5 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.74124820 |
6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.69755740 |
7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.69672128 |
8 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.65895344 |
9 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.64290309 |
10 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.61240656 |
11 | Lysine degradation_Homo sapiens_hsa00310 | 1.60607273 |
12 | Axon guidance_Homo sapiens_hsa04360 | 1.59821613 |
13 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.54943250 |
14 | ABC transporters_Homo sapiens_hsa02010 | 1.52132931 |
15 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.50860788 |
16 | Adherens junction_Homo sapiens_hsa04520 | 1.50852575 |
17 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.41519840 |
18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.40152854 |
19 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.37636432 |
20 | Circadian entrainment_Homo sapiens_hsa04713 | 1.37333593 |
21 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.33855467 |
22 | Nicotine addiction_Homo sapiens_hsa05033 | 1.32406782 |
23 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.31865959 |
24 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.31286683 |
25 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.31094946 |
26 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.30920082 |
27 | Focal adhesion_Homo sapiens_hsa04510 | 1.24106964 |
28 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.23901500 |
29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23243133 |
30 | Renin secretion_Homo sapiens_hsa04924 | 1.20698890 |
31 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.20657208 |
32 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.19249552 |
33 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.18848728 |
34 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.15692125 |
35 | Endometrial cancer_Homo sapiens_hsa05213 | 1.14010282 |
36 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.12408659 |
37 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.08574502 |
38 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.06345294 |
39 | Glioma_Homo sapiens_hsa05214 | 1.05607971 |
40 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.04681432 |
41 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.02785371 |
42 | Morphine addiction_Homo sapiens_hsa05032 | 1.02389146 |
43 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.02315375 |
44 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.01487187 |
45 | Amoebiasis_Homo sapiens_hsa05146 | 1.00421177 |
46 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.95753920 |
47 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.95711607 |
48 | Long-term potentiation_Homo sapiens_hsa04720 | 0.95437048 |
49 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.95206287 |
50 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.93050441 |
51 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.92881492 |
52 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.92433834 |
53 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.90112905 |
54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.89963514 |
55 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.89831422 |
56 | GABAergic synapse_Homo sapiens_hsa04727 | 0.89620641 |
57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.89308916 |
58 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.88932598 |
59 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.88208696 |
60 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.88130659 |
61 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.88059960 |
62 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.87553769 |
63 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.87522232 |
64 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.87343696 |
65 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87009732 |
66 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.84973625 |
67 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.84912765 |
68 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.84725791 |
69 | Insulin resistance_Homo sapiens_hsa04931 | 0.83641056 |
70 | Insulin secretion_Homo sapiens_hsa04911 | 0.83181021 |
71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82435761 |
72 | Salivary secretion_Homo sapiens_hsa04970 | 0.82374621 |
73 | Melanogenesis_Homo sapiens_hsa04916 | 0.82139427 |
74 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.81868416 |
75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.81144677 |
76 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.80398408 |
77 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.79955315 |
78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.79921175 |
79 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.79741356 |
80 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.77590802 |
81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.77465140 |
82 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.77079108 |
83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.76700607 |
84 | Long-term depression_Homo sapiens_hsa04730 | 0.76668524 |
85 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.75928973 |
86 | Cocaine addiction_Homo sapiens_hsa05030 | 0.75920077 |
87 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.75871195 |
88 | Melanoma_Homo sapiens_hsa05218 | 0.75719814 |
89 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.75591266 |
90 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.75532141 |
91 | Taste transduction_Homo sapiens_hsa04742 | 0.75495023 |
92 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.75174693 |
93 | Prostate cancer_Homo sapiens_hsa05215 | 0.73593263 |
94 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.72927149 |
95 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.72329427 |
96 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72131017 |
97 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.72123213 |
98 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.72039934 |
99 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.70885489 |
100 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.70480423 |
101 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.69755906 |
102 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68462356 |
103 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.68376424 |
104 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.68104542 |
105 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66642677 |
106 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.66575445 |
107 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.66402363 |
108 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.65982317 |
109 | Gap junction_Homo sapiens_hsa04540 | 0.65710913 |
110 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.65276671 |
111 | Colorectal cancer_Homo sapiens_hsa05210 | 0.65144978 |
112 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.64189767 |
113 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.63988291 |
114 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63727628 |
115 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63441116 |
116 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62990180 |
117 | Mineral absorption_Homo sapiens_hsa04978 | 0.62617868 |
118 | Bile secretion_Homo sapiens_hsa04976 | 0.61113324 |
119 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.60478326 |
120 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.59616839 |
121 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59265640 |
122 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.58642355 |
123 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58456674 |
124 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58257384 |
125 | Tight junction_Homo sapiens_hsa04530 | 0.58022021 |
126 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.58000513 |
127 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.57439978 |
128 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.56795526 |
129 | Basal transcription factors_Homo sapiens_hsa03022 | 0.55511785 |
130 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.55474910 |
131 | Pathways in cancer_Homo sapiens_hsa05200 | 0.55051741 |
132 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.54659947 |
133 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.54211179 |
134 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.53695433 |
135 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.50960479 |
136 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.50836415 |
137 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.49874583 |
138 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.46887920 |
139 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43586589 |