SBNO1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)7.81069406
2DNA methylation involved in gamete generation (GO:0043046)6.37165125
3nuclear pore complex assembly (GO:0051292)6.04880529
4regulation of meiosis I (GO:0060631)5.77633159
5nuclear pore organization (GO:0006999)5.54289904
6synaptonemal complex assembly (GO:0007130)5.26771813
7male meiosis (GO:0007140)5.23428254
8mitotic sister chromatid cohesion (GO:0007064)4.94172077
9synaptonemal complex organization (GO:0070193)4.93792577
10pore complex assembly (GO:0046931)4.62827105
11sister chromatid cohesion (GO:0007062)4.49159027
12meiotic nuclear division (GO:0007126)4.43841565
13regulation of DNA endoreduplication (GO:0032875)4.28495900
14DNA double-strand break processing (GO:0000729)4.27643783
15chromosome organization involved in meiosis (GO:0070192)4.27215138
16gene silencing by RNA (GO:0031047)4.23005966
17meiotic chromosome segregation (GO:0045132)4.04988265
18replication fork processing (GO:0031297)3.97067420
19DNA alkylation (GO:0006305)3.80058015
20DNA methylation (GO:0006306)3.80058015
21regulation of histone H3-K9 methylation (GO:0051570)3.75634288
22kinetochore organization (GO:0051383)3.74384051
23regulation of protein polyubiquitination (GO:1902914)3.73484063
24negative regulation of DNA-dependent DNA replication (GO:2000104)3.69236468
25male meiosis I (GO:0007141)3.68982164
26somatic diversification of immune receptors via somatic mutation (GO:0002566)3.65919000
27somatic hypermutation of immunoglobulin genes (GO:0016446)3.65919000
28neural tube formation (GO:0001841)3.65532173
29regulation of RNA export from nucleus (GO:0046831)3.62406314
30negative regulation of histone methylation (GO:0031061)3.61718443
31reciprocal meiotic recombination (GO:0007131)3.58188146
32reciprocal DNA recombination (GO:0035825)3.58188146
33maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.51353509
34histone H3-K9 methylation (GO:0051567)3.48449012
35DNA synthesis involved in DNA repair (GO:0000731)3.47220593
36monoubiquitinated protein deubiquitination (GO:0035520)3.41084706
37positive regulation of meiosis (GO:0045836)3.39201407
38protein K6-linked ubiquitination (GO:0085020)3.38677148
39meiotic cell cycle process (GO:1903046)3.36269750
40double-strand break repair via nonhomologous end joining (GO:0006303)3.36196368
41non-recombinational repair (GO:0000726)3.36196368
42negative regulation of DNA repair (GO:0045738)3.34592936
43mitotic chromosome condensation (GO:0007076)3.29867327
44DNA ligation (GO:0006266)3.24537761
45attachment of spindle microtubules to kinetochore (GO:0008608)3.21884933
46snRNA processing (GO:0016180)3.19727469
47regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.19353852
48kinetochore assembly (GO:0051382)3.18562125
49regulation of mitotic spindle checkpoint (GO:1903504)3.17456633
50regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.17456633
51recombinational repair (GO:0000725)3.15921766
52DNA methylation or demethylation (GO:0044728)3.15261040
53regulation of centriole replication (GO:0046599)3.15061353
54positive regulation of mitotic sister chromatid separation (GO:1901970)3.14176240
55positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.14176240
56positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.14176240
57CENP-A containing nucleosome assembly (GO:0034080)3.14040244
58DNA topological change (GO:0006265)3.13997279
59gene silencing (GO:0016458)3.12704658
60centriole replication (GO:0007099)3.11238089
61double-strand break repair via homologous recombination (GO:0000724)3.10566505
62negative regulation of histone modification (GO:0031057)3.10199893
63positive regulation of meiotic cell cycle (GO:0051446)3.05718608
64histone H3-K36 demethylation (GO:0070544)3.04627327
65negative regulation of DNA recombination (GO:0045910)3.03628076
66protein K11-linked deubiquitination (GO:0035871)3.03278153
67pre-miRNA processing (GO:0031054)3.00186098
68histone H3-K4 trimethylation (GO:0080182)2.99878195
69limb bud formation (GO:0060174)2.99457482
70histone demethylation (GO:0016577)2.99453981
71regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.98579495
72microtubule depolymerization (GO:0007019)2.98186451
73regulation of double-strand break repair (GO:2000779)2.96306907
74snRNA metabolic process (GO:0016073)2.96067069
75histone H3-K9 modification (GO:0061647)2.95182573
76meiosis I (GO:0007127)2.95133985
77histone H2A acetylation (GO:0043968)2.94936568
78postreplication repair (GO:0006301)2.94422935
79poly(A)+ mRNA export from nucleus (GO:0016973)2.93565785
80regulation of nucleobase-containing compound transport (GO:0032239)2.93172033
81RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.92749458
82negative regulation of meiosis (GO:0045835)2.92632513
83negative regulation of chromatin modification (GO:1903309)2.92525118
84histone lysine demethylation (GO:0070076)2.90378881
85cilium or flagellum-dependent cell motility (GO:0001539)2.90320794
86oogenesis (GO:0048477)2.90041000
87histone H4-K12 acetylation (GO:0043983)2.88286590
88resolution of meiotic recombination intermediates (GO:0000712)2.88145232
89chromatin remodeling at centromere (GO:0031055)2.88049546
90spindle checkpoint (GO:0031577)2.87741923
91negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.87424759
92negative regulation of translation, ncRNA-mediated (GO:0040033)2.87424759
93regulation of translation, ncRNA-mediated (GO:0045974)2.87424759
94somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.86077857
95isotype switching (GO:0045190)2.86077857
96somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.86077857
97intra-S DNA damage checkpoint (GO:0031573)2.86049106
98regulation of acyl-CoA biosynthetic process (GO:0050812)2.85499204
99response to pheromone (GO:0019236)2.84932319
100protein K48-linked deubiquitination (GO:0071108)2.84288287
101histone H3-K4 methylation (GO:0051568)2.82289184
102mitotic nuclear envelope disassembly (GO:0007077)2.81925169
103regulation of telomere maintenance (GO:0032204)2.81553445
104mRNA export from nucleus (GO:0006406)2.80479672
105mitotic sister chromatid segregation (GO:0000070)2.79684502
106keratinocyte development (GO:0003334)2.78166701
107histone exchange (GO:0043486)2.77884186
108heterochromatin organization (GO:0070828)2.76882666
109metaphase plate congression (GO:0051310)2.76790853
110mitotic spindle checkpoint (GO:0071174)2.76548368
111protein demethylation (GO:0006482)2.76320174
112protein dealkylation (GO:0008214)2.76320174
113proteasome assembly (GO:0043248)2.75769228
114synapsis (GO:0007129)2.75353304
115oocyte development (GO:0048599)2.75061373
116translesion synthesis (GO:0019985)2.74707595
117single strand break repair (GO:0000012)2.73379887
118intraciliary transport (GO:0042073)2.73166077
119mitotic metaphase plate congression (GO:0007080)2.72844275
120regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.72541625
121microtubule anchoring (GO:0034453)2.72071673
122double-strand break repair (GO:0006302)2.71984757
123mRNA transport (GO:0051028)2.70164786
124regulation of centrosome cycle (GO:0046605)2.69753685
125histone H4-K5 acetylation (GO:0043981)2.69709196
126histone H4-K8 acetylation (GO:0043982)2.69709196
127nuclear envelope disassembly (GO:0051081)2.69413392
128membrane disassembly (GO:0030397)2.69413392
129histone H3-K9 demethylation (GO:0033169)2.68804733
130RNA export from nucleus (GO:0006405)2.68713331
131DNA geometric change (GO:0032392)2.68305994
132peptidyl-lysine trimethylation (GO:0018023)2.68073423
133sister chromatid segregation (GO:0000819)2.68070702
134oocyte maturation (GO:0001556)2.67019168
135inner cell mass cell proliferation (GO:0001833)2.65894044
136somatic recombination of immunoglobulin gene segments (GO:0016447)2.65886068
137DNA duplex unwinding (GO:0032508)2.65638980
138telomere maintenance via telomerase (GO:0007004)2.64596357
139histone mRNA catabolic process (GO:0071044)2.64224009
140regulation of cofactor metabolic process (GO:0051193)2.64183237
141regulation of coenzyme metabolic process (GO:0051196)2.64183237
142DNA catabolic process, exonucleolytic (GO:0000738)2.63762817
143somatic diversification of immunoglobulins (GO:0016445)2.63164206
144regulation of centrosome duplication (GO:0010824)2.62273246
145pyrimidine nucleobase catabolic process (GO:0006208)2.61028135
146regulation of sister chromatid segregation (GO:0033045)2.55228505
147regulation of mitotic sister chromatid separation (GO:0010965)2.55228505
148regulation of mitotic sister chromatid segregation (GO:0033047)2.55228505
149protein-cofactor linkage (GO:0018065)2.54463926
150nucleotide-excision repair, DNA gap filling (GO:0006297)2.54217951
151DNA recombination (GO:0006310)2.53662435
152establishment of chromosome localization (GO:0051303)2.53436674
153negative regulation of dendrite development (GO:2000171)2.53226100
154protein localization to kinetochore (GO:0034501)2.51991249
155DNA-dependent DNA replication (GO:0006261)2.51250431
156somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.51135894
157somatic cell DNA recombination (GO:0016444)2.51135894
158microtubule organizing center organization (GO:0031023)2.50528858
159somatic diversification of immune receptors (GO:0002200)2.50399286
160centrosome organization (GO:0051297)2.50330366
161regulation of nuclear cell cycle DNA replication (GO:0033262)2.48526710

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.78064767
2* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.63236741
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.59828692
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.56064746
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.52223268
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.41254158
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.18210945
8ZNF274_21170338_ChIP-Seq_K562_Hela3.02625292
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.99248450
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.93753333
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.87332125
12IGF1R_20145208_ChIP-Seq_DFB_Human2.53176001
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.35954956
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.33612419
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.32082962
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.30763242
17GABP_17652178_ChIP-ChIP_JURKAT_Human2.28862612
18TP63_19390658_ChIP-ChIP_HaCaT_Human2.19802721
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.14454068
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09764825
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.08319472
22VDR_22108803_ChIP-Seq_LS180_Human2.07363460
23YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.98108139
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.97294768
25* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.94340365
26FUS_26573619_Chip-Seq_HEK293_Human1.92770057
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.86151723
28SMAD_19615063_ChIP-ChIP_OVARY_Human1.83410255
29HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.76652560
30EWS_26573619_Chip-Seq_HEK293_Human1.75544111
31FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.75514454
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71513872
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69354969
34CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66949639
35PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65422929
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53060417
37PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52978742
38GBX2_23144817_ChIP-Seq_PC3_Human1.52727012
39HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.51042488
40MYC_18940864_ChIP-ChIP_HL60_Human1.46347113
41* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.44749636
42* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.42403634
43CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41760085
44IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41560266
45CBP_20019798_ChIP-Seq_JUKART_Human1.41560266
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40710851
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.40176182
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.38898608
49FOXP3_21729870_ChIP-Seq_TREG_Human1.36279271
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.35263279
51UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34827790
52PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.32082120
53TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.31020458
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28052808
55TCF4_23295773_ChIP-Seq_U87_Human1.27889845
56IRF1_19129219_ChIP-ChIP_H3396_Human1.27595534
57ELK1_19687146_ChIP-ChIP_HELA_Human1.26992649
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.26963508
59BCAT_22108803_ChIP-Seq_LS180_Human1.25789677
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.25488819
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24327921
62ETS1_20019798_ChIP-Seq_JURKAT_Human1.23909251
63RNF2_27304074_Chip-Seq_NSC_Mouse1.23426542
64AR_21909140_ChIP-Seq_LNCAP_Human1.23396714
65AR_25329375_ChIP-Seq_VCAP_Human1.23048338
66NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.22804202
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.22636771
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22614665
69PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22215557
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.21949283
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21796650
72STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.21764368
73RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21200330
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.20552187
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19594232
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.19545958
77TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.19281522
78STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.18606353
79PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18091595
80PKCTHETA_26484144_Chip-Seq_BREAST_Human1.17269252
81TP53_16413492_ChIP-PET_HCT116_Human1.16729443
82STAT3_23295773_ChIP-Seq_U87_Human1.16708123
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16646818
84E2F1_18555785_Chip-Seq_ESCs_Mouse1.16492535
85AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15142985
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13998918
87JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.13899534
88TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13676964
89NANOG_18555785_Chip-Seq_ESCs_Mouse1.10349466
90* TP53_22573176_ChIP-Seq_HFKS_Human1.09818651
91* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.09815009
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09625094
93FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.09533894
94CIITA_25753668_ChIP-Seq_RAJI_Human1.09479834
95SMAD4_21799915_ChIP-Seq_A2780_Human1.09281969
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07898181
97EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06877028
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06729126
99TCF4_22108803_ChIP-Seq_LS180_Human1.06092518
100ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04641884
101TAF15_26573619_Chip-Seq_HEK293_Human1.02730915
102NANOG_19829295_ChIP-Seq_ESCs_Human1.01594987
103SOX2_19829295_ChIP-Seq_ESCs_Human1.01594987
104CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01204797
105TCF4_18268006_ChIP-ChIP_LS174T_Human0.99655379
106SOX9_26525672_Chip-Seq_HEART_Mouse0.98635036
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.98320822
108* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98071132
109FLI1_21867929_ChIP-Seq_TH2_Mouse0.97894156
110HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97004638
111* RUNX2_22187159_ChIP-Seq_PCA_Human0.96390206
112CRX_20693478_ChIP-Seq_RETINA_Mouse0.95867919
113NOTCH1_21737748_ChIP-Seq_TLL_Human0.95853715
114FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95364281
115SOX2_16153702_ChIP-ChIP_HESCs_Human0.94941608
116P300_19829295_ChIP-Seq_ESCs_Human0.93528180
117EZH2_27294783_Chip-Seq_NPCs_Mouse0.93418204
118POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92667365
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92667365
120SUZ12_18555785_Chip-Seq_ESCs_Mouse0.91262903
121EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90925906
122P53_22387025_ChIP-Seq_ESCs_Mouse0.90433157
123STAT3_18555785_Chip-Seq_ESCs_Mouse0.90160743
124EZH2_22144423_ChIP-Seq_EOC_Human0.88604865
125CMYC_18555785_Chip-Seq_ESCs_Mouse0.88507168
126SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.88500839
127FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.87940929
128SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.87735286
129POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87173458
130* KDM5A_27292631_Chip-Seq_BREAST_Human0.85554146
131VDR_23849224_ChIP-Seq_CD4+_Human0.84877452
132RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.84544919
133* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.83993700
134ER_23166858_ChIP-Seq_MCF-7_Human0.83887040
135OCT4_18555785_Chip-Seq_ESCs_Mouse0.81564391
136GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80978069
137BP1_19119308_ChIP-ChIP_Hs578T_Human0.80790894
138MYC_19030024_ChIP-ChIP_MESCs_Mouse0.80473677
139NMYC_18555785_Chip-Seq_ESCs_Mouse0.80150942
140P300_18555785_Chip-Seq_ESCs_Mouse0.80041154
141CTNNB1_20460455_ChIP-Seq_HCT116_Human0.79967265
142RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.79816680
143TFEB_21752829_ChIP-Seq_HELA_Human0.79111298
144YAP1_20516196_ChIP-Seq_MESCs_Mouse0.78099008
145EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.76999881
146TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.76386761
147CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.76233431
148KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.75983329

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation7.01352844
2MP0008057_abnormal_DNA_replication4.03117481
3MP0010094_abnormal_chromosome_stability3.56405374
4MP0008058_abnormal_DNA_repair3.03067491
5MP0003787_abnormal_imprinting2.91699321
6MP0000569_abnormal_digit_pigmentation2.87701262
7MP0003123_paternal_imprinting2.82083703
8MP0008995_early_reproductive_senescence2.78490026
9MP0003111_abnormal_nucleus_morphology2.68708272
10MP0003121_genomic_imprinting2.66655444
11MP0002210_abnormal_sex_determination2.60306335
12MP0002102_abnormal_ear_morphology2.56301626
13MP0008007_abnormal_cellular_replicative2.48824989
14MP0003077_abnormal_cell_cycle2.45521642
15MP0003786_premature_aging2.40149501
16MP0001929_abnormal_gametogenesis2.24393377
17MP0003718_maternal_effect2.12080723
18MP0003693_abnormal_embryo_hatching2.05296118
19MP0001145_abnormal_male_reproductive2.00776248
20MP0010307_abnormal_tumor_latency2.00370654
21MP0004808_abnormal_hematopoietic_stem1.98293333
22MP0003890_abnormal_embryonic-extraembry1.94991448
23MP0003698_abnormal_male_reproductive1.92212933
24MP0002009_preneoplasia1.91168310
25MP0003195_calcinosis1.82683168
26MP0000653_abnormal_sex_gland1.79986541
27MP0000372_irregular_coat_pigmentation1.78659767
28MP0001984_abnormal_olfaction1.77999820
29MP0001188_hyperpigmentation1.77344758
30MP0010352_gastrointestinal_tract_polyps1.76862163
31MP0004957_abnormal_blastocyst_morpholog1.76605243
32MP0002234_abnormal_pharynx_morphology1.72806434
33MP0002938_white_spotting1.64055353
34MP0006072_abnormal_retinal_apoptosis1.63521748
35MP0002396_abnormal_hematopoietic_system1.59275378
36MP0001529_abnormal_vocalization1.56658232
37MP0000015_abnormal_ear_pigmentation1.47247642
38MP0000350_abnormal_cell_proliferation1.46328586
39MP0005551_abnormal_eye_electrophysiolog1.41228268
40MP0002160_abnormal_reproductive_system1.40364913
41MP0002736_abnormal_nociception_after1.39889778
42MP0002751_abnormal_autonomic_nervous1.38296924
43MP0005076_abnormal_cell_differentiation1.38136124
44MP0000778_abnormal_nervous_system1.35821271
45MP0009697_abnormal_copulation1.35384933
46MP0009046_muscle_twitch1.32883522
47MP0000647_abnormal_sebaceous_gland1.30449391
48MP0001730_embryonic_growth_arrest1.30405720
49MP0005253_abnormal_eye_physiology1.29664035
50MP0001672_abnormal_embryogenesis/_devel1.28741314
51MP0005380_embryogenesis_phenotype1.28741314
52MP0002638_abnormal_pupillary_reflex1.23890689
53MP0003122_maternal_imprinting1.22916956
54MP0003984_embryonic_growth_retardation1.22467769
55MP0000631_abnormal_neuroendocrine_gland1.22371657
56MP0000383_abnormal_hair_follicle1.22185659
57MP0002088_abnormal_embryonic_growth/wei1.18835103
58MP0003119_abnormal_digestive_system1.18000197
59MP0004197_abnormal_fetal_growth/weight/1.17709508
60MP0005084_abnormal_gallbladder_morpholo1.17455008
61MP0008789_abnormal_olfactory_epithelium1.17114715
62MP0005410_abnormal_fertilization1.16328378
63MP0006035_abnormal_mitochondrial_morpho1.15676235
64MP0005646_abnormal_pituitary_gland1.14688384
65MP0002233_abnormal_nose_morphology1.14252990
66MP0001119_abnormal_female_reproductive1.13847804
67MP0002084_abnormal_developmental_patter1.13421308
68MP0004147_increased_porphyrin_level1.13218925
69MP0005367_renal/urinary_system_phenotyp1.12171213
70MP0000516_abnormal_urinary_system1.12171213
71MP0001968_abnormal_touch/_nociception1.11990785
72MP0006276_abnormal_autonomic_nervous1.10439437
73MP0008932_abnormal_embryonic_tissue1.09739033
74MP0005174_abnormal_tail_pigmentation1.08554660
75MP0001293_anophthalmia1.07319636
76MP0010678_abnormal_skin_adnexa1.07073397
77MP0005394_taste/olfaction_phenotype1.06944718
78MP0005499_abnormal_olfactory_system1.06944718
79MP0002161_abnormal_fertility/fecundity1.06333095
80MP0006292_abnormal_olfactory_placode1.05885476
81MP0002086_abnormal_extraembryonic_tissu1.05653375
82MP0005187_abnormal_penis_morphology1.05438382
83MP0004270_analgesia1.02877515
84MP0005409_darkened_coat_color1.00719911
85MP0002085_abnormal_embryonic_tissue0.99663705
86MP0003943_abnormal_hepatobiliary_system0.99188210
87MP0002075_abnormal_coat/hair_pigmentati0.98162158
88MP0009703_decreased_birth_body0.97730232
89MP0001697_abnormal_embryo_size0.96933789
90MP0002006_tumorigenesis0.96677803
91MP0005389_reproductive_system_phenotype0.96112910
92MP0005395_other_phenotype0.95798101
93MP0001286_abnormal_eye_development0.94299856
94MP0006054_spinal_hemorrhage0.94005586
95MP0008872_abnormal_physiological_respon0.93921211
96MP0005171_absent_coat_pigmentation0.92609232
97MP0002166_altered_tumor_susceptibility0.92016473
98MP0003763_abnormal_thymus_physiology0.90730948
99MP0000703_abnormal_thymus_morphology0.89990309
100MP0004924_abnormal_behavior0.88850287
101MP0005386_behavior/neurological_phenoty0.88850287
102MP0000313_abnormal_cell_death0.88555050
103MP0002877_abnormal_melanocyte_morpholog0.87635348
104MP0000371_diluted_coat_color0.85607696
105MP0001486_abnormal_startle_reflex0.85551425
106MP0001186_pigmentation_phenotype0.84264776
107MP0002095_abnormal_skin_pigmentation0.83238574
108MP0003115_abnormal_respiratory_system0.82150153
109MP0005391_vision/eye_phenotype0.79936305
110MP0002080_prenatal_lethality0.79759210
111MP0002272_abnormal_nervous_system0.79750308
112MP0005397_hematopoietic_system_phenotyp0.79424165
113MP0001545_abnormal_hematopoietic_system0.79424165
114MP0009745_abnormal_behavioral_response0.78293730
115MP0003937_abnormal_limbs/digits/tail_de0.78209174
116MP0003941_abnormal_skin_development0.78153273
117MP0005075_abnormal_melanosome_morpholog0.77597765
118MP0003315_abnormal_perineum_morphology0.77556369
119MP0002398_abnormal_bone_marrow0.74883372
120MP0002928_abnormal_bile_duct0.73799284
121MP0005623_abnormal_meninges_morphology0.73078347
122MP0003567_abnormal_fetal_cardiomyocyte0.73003889
123MP0001177_atelectasis0.72831192
124MP0002184_abnormal_innervation0.72232785
125MP0003861_abnormal_nervous_system0.72075739
126MP0000427_abnormal_hair_cycle0.70940816
127MP0004215_abnormal_myocardial_fiber0.70876193
128MP0001915_intracranial_hemorrhage0.69940566
129MP0001299_abnormal_eye_distance/0.69371407
130MP0002019_abnormal_tumor_incidence0.68777758
131MP0003880_abnormal_central_pattern0.65846502
132MP0001919_abnormal_reproductive_system0.65335297
133MP0009672_abnormal_birth_weight0.65052092
134MP0003699_abnormal_female_reproductive0.64380625
135MP0009278_abnormal_bone_marrow0.64306411
136MP0000432_abnormal_head_morphology0.62364206
137MP0000537_abnormal_urethra_morphology0.61818277
138MP0003936_abnormal_reproductive_system0.61112430
139MP0005621_abnormal_cell_physiology0.58627887
140MP0003136_yellow_coat_color0.57460666
141MP0005384_cellular_phenotype0.57449347
142MP0002925_abnormal_cardiovascular_devel0.56079812
143MP0003935_abnormal_craniofacial_develop0.55981581
144MP0000490_abnormal_crypts_of0.53505736
145MP0003755_abnormal_palate_morphology0.50999296
146MP0000428_abnormal_craniofacial_morphol0.50183963
147MP0005377_hearing/vestibular/ear_phenot0.49538033
148MP0003878_abnormal_ear_physiology0.49538033

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.93831475
2Chromosomal breakage induced by crosslinking agents (HP:0003221)3.85688575
3Abnormality of the fingertips (HP:0001211)3.78925940
4Volvulus (HP:0002580)3.75771386
5Azoospermia (HP:0000027)3.41557838
6Papillary thyroid carcinoma (HP:0002895)3.41437930
7Abnormal spermatogenesis (HP:0008669)3.40971297
8Ectopic kidney (HP:0000086)3.12383182
9Pancreatic cysts (HP:0001737)2.94102688
10Abnormality of chromosome stability (HP:0003220)2.83189722
11Abnormality of the lower motor neuron (HP:0002366)2.71179849
12Impulsivity (HP:0100710)2.64948734
13Abnormal hair whorl (HP:0010721)2.62489887
14Abnormality of the labia minora (HP:0012880)2.62093252
15Truncal obesity (HP:0001956)2.60795227
16Long eyelashes (HP:0000527)2.59940735
17Medial flaring of the eyebrow (HP:0010747)2.58001469
18Intestinal atresia (HP:0011100)2.54353319
19Tubulointerstitial nephritis (HP:0001970)2.53746905
20Nephroblastoma (Wilms tumor) (HP:0002667)2.51689667
21Aplasia/Hypoplasia of the uvula (HP:0010293)2.50781661
22Oligodactyly (hands) (HP:0001180)2.49525388
23Abnormality of the nasal septum (HP:0000419)2.46044659
24Thyroid carcinoma (HP:0002890)2.45844492
25Meckel diverticulum (HP:0002245)2.43458682
2611 pairs of ribs (HP:0000878)2.42060973
27Hypoplastic pelvis (HP:0008839)2.39306139
28Myelodysplasia (HP:0002863)2.39290919
29Deep philtrum (HP:0002002)2.39102302
30Small hand (HP:0200055)2.38000880
31Thyroiditis (HP:0100646)2.36467775
32True hermaphroditism (HP:0010459)2.35437902
33Embryonal renal neoplasm (HP:0011794)2.32340082
34Absent frontal sinuses (HP:0002688)2.31338259
35Lip pit (HP:0100267)2.30615828
36Methylmalonic acidemia (HP:0002912)2.28282084
37Abnormality of the renal cortex (HP:0011035)2.26444203
38Abnormality of the ileum (HP:0001549)2.25824444
39Prominent nose (HP:0000448)2.25526828
40Abnormality of the preputium (HP:0100587)2.23892017
41Renal cortical cysts (HP:0000803)2.23462240
42Hyperventilation (HP:0002883)2.19613108
43Hypothermia (HP:0002045)2.19380189
44Medulloblastoma (HP:0002885)2.18701144
45Congenital primary aphakia (HP:0007707)2.18512689
46Gait imbalance (HP:0002141)2.17914853
47Febrile seizures (HP:0002373)2.16076381
48Urethral obstruction (HP:0000796)2.15066622
49Birth length less than 3rd percentile (HP:0003561)2.12820338
50Genital tract atresia (HP:0001827)2.10793430
51Gonadotropin excess (HP:0000837)2.10634376
52Nephrogenic diabetes insipidus (HP:0009806)2.10248926
53Acute myeloid leukemia (HP:0004808)2.08464251
54Nephronophthisis (HP:0000090)2.07296463
55Increased nuchal translucency (HP:0010880)2.04879670
56Abnormality of the astrocytes (HP:0100707)2.03205514
57Astrocytoma (HP:0009592)2.03205514
58Lissencephaly (HP:0001339)2.02570234
59Abnormality of the carotid arteries (HP:0005344)2.02149804
60Duodenal stenosis (HP:0100867)2.01803027
61Small intestinal stenosis (HP:0012848)2.01803027
62Hypoplastic female external genitalia (HP:0012815)2.01183774
63Vaginal atresia (HP:0000148)2.01146413
64Drooling (HP:0002307)1.99436989
65Aqueductal stenosis (HP:0002410)1.98795528
66Chronic hepatic failure (HP:0100626)1.97838370
67Astigmatism (HP:0000483)1.95574310
68Absent/shortened dynein arms (HP:0200106)1.95218653
69Dynein arm defect of respiratory motile cilia (HP:0012255)1.95218653
70Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94762344
71Neoplasm of the adrenal cortex (HP:0100641)1.94633967
72Supernumerary spleens (HP:0009799)1.94418784
73Glioma (HP:0009733)1.93980545
74Clubbing of toes (HP:0100760)1.93966160
75Aplasia/Hypoplasia of the tongue (HP:0010295)1.93366557
76Subacute progressive viral hepatitis (HP:0006572)1.92358275
77Intestinal fistula (HP:0100819)1.92216089
78Short 4th metacarpal (HP:0010044)1.91980142
79Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.91980142
80Ependymoma (HP:0002888)1.91387976
81Cutaneous melanoma (HP:0012056)1.90878983
82Abnormality of chromosome segregation (HP:0002916)1.88862989
83Agnosia (HP:0010524)1.88289808
84Facial hemangioma (HP:0000329)1.87599895
85Abnormality of the renal medulla (HP:0100957)1.86500081
86Deviation of the thumb (HP:0009603)1.84926903
87Sloping forehead (HP:0000340)1.84802470
88Narrow palate (HP:0000189)1.83612770
89Bifid tongue (HP:0010297)1.83472864
90Labial hypoplasia (HP:0000066)1.82251138
91Cafe-au-lait spot (HP:0000957)1.80740067
92Heterotopia (HP:0002282)1.79635339
93Protruding tongue (HP:0010808)1.79295413
94Neoplasm of the adrenal gland (HP:0100631)1.78958529
95Colon cancer (HP:0003003)1.78749665
96Amyotrophic lateral sclerosis (HP:0007354)1.78246864
97Anal stenosis (HP:0002025)1.77788000
98Proximal placement of thumb (HP:0009623)1.77092526
99Absent speech (HP:0001344)1.76234649
100Carpal bone hypoplasia (HP:0001498)1.75841232
101Prostate neoplasm (HP:0100787)1.75305120
102Renal hypoplasia (HP:0000089)1.75291583
103Narrow forehead (HP:0000341)1.75035300
104Poor coordination (HP:0002370)1.74707197
105Degeneration of anterior horn cells (HP:0002398)1.74000767
106Abnormality of the anterior horn cell (HP:0006802)1.74000767
107Optic nerve hypoplasia (HP:0000609)1.73128465
108Syringomyelia (HP:0003396)1.73012696
109Spinal cord lesions (HP:0100561)1.73012696
110Excessive salivation (HP:0003781)1.72975198
111Obsessive-compulsive behavior (HP:0000722)1.72749927
112Pancreatic fibrosis (HP:0100732)1.72605189
113Abnormality of incisor morphology (HP:0011063)1.71957596
114Dandy-Walker malformation (HP:0001305)1.71811723
115Preaxial hand polydactyly (HP:0001177)1.71288487
116Abnormal lung lobation (HP:0002101)1.70793837
117Abnormality of the columella (HP:0009929)1.69422330
118Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.68406542
119Abnormality of alanine metabolism (HP:0010916)1.68406542
120Hyperalaninemia (HP:0003348)1.68406542
121Oligodactyly (HP:0012165)1.67241839
122Postaxial foot polydactyly (HP:0001830)1.66299486
123Pendular nystagmus (HP:0012043)1.66112123
124Abnormality of the metopic suture (HP:0005556)1.64749055
125Sandal gap (HP:0001852)1.64575321
126Gaze-evoked nystagmus (HP:0000640)1.64321748
127Highly arched eyebrow (HP:0002553)1.63907452
128Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63649489
129Abnormality of the incisor (HP:0000676)1.63356842
130Abnormality of the parathyroid morphology (HP:0011766)1.63338800
131Type II lissencephaly (HP:0007260)1.63163877
132Cystic hygroma (HP:0000476)1.62715286
133Absent thumb (HP:0009777)1.61835541
134Abnormality of the duodenum (HP:0002246)1.61757815
135Aplasia/Hypoplasia of the tibia (HP:0005772)1.61337982
136Aplasia/Hypoplasia of the sternum (HP:0006714)1.61017741
137Fibular hypoplasia (HP:0003038)1.60895157
138Severe combined immunodeficiency (HP:0004430)1.60817574
139Breast carcinoma (HP:0003002)1.59989915
140Long clavicles (HP:0000890)1.59502485
141Abnormality of aspartate family amino acid metabolism (HP:0010899)1.59415869
142Molar tooth sign on MRI (HP:0002419)1.59351672
143Abnormality of midbrain morphology (HP:0002418)1.59351672
144Duplicated collecting system (HP:0000081)1.58640216
145Oculomotor apraxia (HP:0000657)1.58005332
146Biliary tract neoplasm (HP:0100574)1.57968968
147Rhabdomyosarcoma (HP:0002859)1.57477386
148Fair hair (HP:0002286)1.57119757
149Neoplasm of the oral cavity (HP:0100649)1.56687142
150Supernumerary ribs (HP:0005815)1.56626639
151Methylmalonic aciduria (HP:0012120)1.55863643
152Shawl scrotum (HP:0000049)1.55782485
153Absent eyebrow (HP:0002223)1.54886120
154Shoulder girdle muscle weakness (HP:0003547)1.54109973
155Postaxial hand polydactyly (HP:0001162)1.53357139
156Hip dysplasia (HP:0001385)1.52843336
157Delayed gross motor development (HP:0002194)1.52773269

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.24158215
2CDC74.23695718
3BRD44.20509639
4TRIM283.02512684
5MAP4K22.90566427
6AKT32.83525275
7MKNK22.48751476
8EIF2AK32.40865879
9ZAK2.11928433
10TNIK2.07104650
11SGK22.02732777
12MKNK11.90809087
13SRPK11.89621228
14CASK1.82121765
15FRK1.81823216
16ACVR1B1.80641255
17ATR1.74573033
18PLK31.72518806
19BCR1.66143248
20SIK31.63951017
21PRPF4B1.61951852
22WEE11.55677407
23MST41.55533275
24TSSK61.55316737
25BRSK21.53915515
26CHEK11.52484055
27PLK21.52077112
28MAP3K141.50101013
29SGK31.49251808
30STK38L1.45090312
31NEK11.44407684
32ATM1.43746132
33MAP3K41.43610050
34TTK1.42867431
35MARK11.39269789
36PLK11.38332679
37EIF2AK11.35667282
38PAK31.33145004
39STK31.24930769
40NUAK11.23129524
41CSNK1G11.20812649
42PNCK1.20691940
43STK241.17795239
44NEK21.17659617
45PDK41.17625635
46PDK31.17625635
47CLK11.17329948
48LATS11.16574708
49PINK11.15492340
50CHEK21.14083885
51NTRK31.13082604
52TXK1.05815070
53FGFR21.03194949
54STK40.96974820
55CDK90.96598543
56YES10.96135730
57CSNK1G20.95881410
58CSNK1G30.93627561
59CHUK0.93473940
60MINK10.92182612
61WNK10.92156207
62PLK40.92026968
63CDK20.91983300
64CDK80.91616829
65STK390.90342324
66PBK0.89877110
67MELK0.88425221
68CDK70.87344694
69RPS6KB10.85510247
70CDK30.84609243
71CCNB10.83201576
72ERBB30.82348240
73MAP2K70.82121542
74OXSR10.82085560
75CAMK1G0.80878482
76CDK10.80814978
77SGK4940.80253461
78SGK2230.80253461
79PASK0.79610032
80FGFR30.79479750
81MAPK130.79407550
82CSNK1A1L0.78664868
83CDK40.78456802
84CAMK1D0.76921709
85SGK10.75551236
86GRK10.75307285
87TAOK30.72935580
88EIF2AK20.72430563
89TGFBR10.68784974
90FLT30.67546652
91CDC42BPA0.66989364
92ADRBK20.66957737
93AURKB0.66902804
94NEK60.66847971
95INSRR0.66303498
96DYRK20.66290835
97MARK30.66072432
98MAPK140.65718806
99PDK20.64429202
100TAF10.63278852
101PRKDC0.62360526
102GSK3B0.61270038
103CSNK1D0.61105794
104JAK30.60759737
105PRKCE0.60413219
106FER0.57718472
107VRK10.55415635
108SCYL20.54438144
109CDK60.54377994
110PRKCI0.53751165
111MTOR0.52887820
112PDGFRB0.51813711
113MAPK100.50879941
114PRKCG0.50051182
115KSR10.48750291
116PTK2B0.48742187
117DYRK30.47987671
118ERBB40.47844916
119WNK30.47829230
120PIM10.47741915
121MAPK80.47488963
122FGFR10.46917290
123DAPK10.46567834
124CSNK1E0.45090971
125CAMK40.44253600
126BUB10.43871358
127RAF10.43449729
128BRSK10.42906360
129BMPR1B0.42647197
130ALK0.39809875
131RIPK40.39125419
132EPHA40.38369146
133NLK0.38262359
134AKT10.38204749
135TRPM70.37431030
136PRKD30.36817212
137MAPK10.34999025
138CSNK1A10.34819134
139PKN10.34425537
140DYRK1A0.34217057
141PRKACB0.31319569
142STK160.30542388
143CSNK2A10.30322358
144MAP3K120.29980390
145CSNK2A20.26366319

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.95919291
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.94640758
3Protein export_Homo sapiens_hsa030602.71907679
4Homologous recombination_Homo sapiens_hsa034402.68269874
5Basal transcription factors_Homo sapiens_hsa030222.62185489
6Propanoate metabolism_Homo sapiens_hsa006402.47519668
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.46574478
8mRNA surveillance pathway_Homo sapiens_hsa030152.36247480
9Mismatch repair_Homo sapiens_hsa034302.34202389
10Selenocompound metabolism_Homo sapiens_hsa004502.18030044
11Cell cycle_Homo sapiens_hsa041102.14403232
12DNA replication_Homo sapiens_hsa030302.08041694
13Non-homologous end-joining_Homo sapiens_hsa034502.04806927
14RNA transport_Homo sapiens_hsa030132.01943293
15Proteasome_Homo sapiens_hsa030502.01301908
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.91097278
17Butanoate metabolism_Homo sapiens_hsa006501.79317938
18RNA degradation_Homo sapiens_hsa030181.73200494
19Spliceosome_Homo sapiens_hsa030401.66656216
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.66230312
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.64294016
22Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61194254
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.56100139
24Nucleotide excision repair_Homo sapiens_hsa034201.54350507
25Dorso-ventral axis formation_Homo sapiens_hsa043201.49416210
26Fatty acid elongation_Homo sapiens_hsa000621.46990098
27Base excision repair_Homo sapiens_hsa034101.45834936
28Steroid biosynthesis_Homo sapiens_hsa001001.44348356
29RNA polymerase_Homo sapiens_hsa030201.41290582
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38125529
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.34683720
32One carbon pool by folate_Homo sapiens_hsa006701.32133643
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.30522405
34Oocyte meiosis_Homo sapiens_hsa041141.28090539
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.27989757
36Regulation of autophagy_Homo sapiens_hsa041401.17008426
37Herpes simplex infection_Homo sapiens_hsa051681.16869343
38Long-term potentiation_Homo sapiens_hsa047201.16104110
39Thyroid cancer_Homo sapiens_hsa052161.09075084
40MicroRNAs in cancer_Homo sapiens_hsa052061.08158976
41Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06748729
42Nitrogen metabolism_Homo sapiens_hsa009101.02956734
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02945066
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.02650131
45p53 signaling pathway_Homo sapiens_hsa041151.01921339
46Pyruvate metabolism_Homo sapiens_hsa006201.00641537
47Antigen processing and presentation_Homo sapiens_hsa046120.99458600
48Colorectal cancer_Homo sapiens_hsa052100.99355130
49NF-kappa B signaling pathway_Homo sapiens_hsa040640.96267282
50Epstein-Barr virus infection_Homo sapiens_hsa051690.96155379
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.95195963
52Viral carcinogenesis_Homo sapiens_hsa052030.93970470
53Nicotine addiction_Homo sapiens_hsa050330.92603620
54HTLV-I infection_Homo sapiens_hsa051660.92501722
55Thyroid hormone signaling pathway_Homo sapiens_hsa049190.92298027
56Endometrial cancer_Homo sapiens_hsa052130.90483840
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90439314
58Type I diabetes mellitus_Homo sapiens_hsa049400.88382037
59Prostate cancer_Homo sapiens_hsa052150.88227403
60Peroxisome_Homo sapiens_hsa041460.86972671
61Influenza A_Homo sapiens_hsa051640.86172504
62TGF-beta signaling pathway_Homo sapiens_hsa043500.81985887
63Lysine degradation_Homo sapiens_hsa003100.81499970
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.81479744
65T cell receptor signaling pathway_Homo sapiens_hsa046600.81464892
66FoxO signaling pathway_Homo sapiens_hsa040680.81407110
67Fatty acid metabolism_Homo sapiens_hsa012120.80659389
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.80232399
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.80112510
70Ether lipid metabolism_Homo sapiens_hsa005650.78057310
71Inositol phosphate metabolism_Homo sapiens_hsa005620.77710851
72Tryptophan metabolism_Homo sapiens_hsa003800.76900934
73Measles_Homo sapiens_hsa051620.76890369
74Type II diabetes mellitus_Homo sapiens_hsa049300.75767241
75Adherens junction_Homo sapiens_hsa045200.74809953
76Small cell lung cancer_Homo sapiens_hsa052220.74777485
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74765978
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74593977
79Graft-versus-host disease_Homo sapiens_hsa053320.74561470
80Hedgehog signaling pathway_Homo sapiens_hsa043400.73022148
81Wnt signaling pathway_Homo sapiens_hsa043100.69335353
82ErbB signaling pathway_Homo sapiens_hsa040120.68978208
83Taste transduction_Homo sapiens_hsa047420.68934776
84Amphetamine addiction_Homo sapiens_hsa050310.68625373
85Hepatitis B_Homo sapiens_hsa051610.67895002
86mTOR signaling pathway_Homo sapiens_hsa041500.66686316
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.66284489
88Glioma_Homo sapiens_hsa052140.66155766
89Non-small cell lung cancer_Homo sapiens_hsa052230.65148873
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63657637
91Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63208222
92Pancreatic cancer_Homo sapiens_hsa052120.63178135
93Oxidative phosphorylation_Homo sapiens_hsa001900.62982819
94Vitamin B6 metabolism_Homo sapiens_hsa007500.62421664
95Purine metabolism_Homo sapiens_hsa002300.61582911
96Primary immunodeficiency_Homo sapiens_hsa053400.60980878
97Systemic lupus erythematosus_Homo sapiens_hsa053220.60141006
98Circadian entrainment_Homo sapiens_hsa047130.60044624
99Parkinsons disease_Homo sapiens_hsa050120.59598022
100Chronic myeloid leukemia_Homo sapiens_hsa052200.58971928
101Phototransduction_Homo sapiens_hsa047440.58963980
102Allograft rejection_Homo sapiens_hsa053300.56523866
103Hematopoietic cell lineage_Homo sapiens_hsa046400.55437402
104Prolactin signaling pathway_Homo sapiens_hsa049170.55289103
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54953174
106Olfactory transduction_Homo sapiens_hsa047400.54380931
107MAPK signaling pathway_Homo sapiens_hsa040100.54205313
108Sulfur metabolism_Homo sapiens_hsa009200.53827664
109Huntingtons disease_Homo sapiens_hsa050160.53683030
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.53353594
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52588860
112Alcoholism_Homo sapiens_hsa050340.52535175
113Long-term depression_Homo sapiens_hsa047300.52493011
114beta-Alanine metabolism_Homo sapiens_hsa004100.52207963
115Toxoplasmosis_Homo sapiens_hsa051450.52117834
116Caffeine metabolism_Homo sapiens_hsa002320.51133673
117cGMP-PKG signaling pathway_Homo sapiens_hsa040220.50596920
118Acute myeloid leukemia_Homo sapiens_hsa052210.50392765
119Leishmaniasis_Homo sapiens_hsa051400.50287507
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49327268
121Circadian rhythm_Homo sapiens_hsa047100.48176134
122Metabolic pathways_Homo sapiens_hsa011000.47877552
123Linoleic acid metabolism_Homo sapiens_hsa005910.47605602
124Hippo signaling pathway_Homo sapiens_hsa043900.47438877
125Oxytocin signaling pathway_Homo sapiens_hsa049210.47246708
126Collecting duct acid secretion_Homo sapiens_hsa049660.46892714
127Pathways in cancer_Homo sapiens_hsa052000.46569846
128cAMP signaling pathway_Homo sapiens_hsa040240.46393458
129Dopaminergic synapse_Homo sapiens_hsa047280.46336909
130Glucagon signaling pathway_Homo sapiens_hsa049220.45662518
131Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.45231123
132B cell receptor signaling pathway_Homo sapiens_hsa046620.44631396
133Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43704721
134Pyrimidine metabolism_Homo sapiens_hsa002400.43510219
135Morphine addiction_Homo sapiens_hsa050320.43387136
136Osteoclast differentiation_Homo sapiens_hsa043800.43272874
137Chemokine signaling pathway_Homo sapiens_hsa040620.42836445
138Estrogen signaling pathway_Homo sapiens_hsa049150.41990572
139Autoimmune thyroid disease_Homo sapiens_hsa053200.41965199
140Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41556284
141Calcium signaling pathway_Homo sapiens_hsa040200.41408207
142Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.41139643
143Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41095821
144Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40029858
145alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.39070229
146Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35841129
147GABAergic synapse_Homo sapiens_hsa047270.30594174
148Basal cell carcinoma_Homo sapiens_hsa052170.29219051
149Fatty acid degradation_Homo sapiens_hsa000710.29001227
150Primary bile acid biosynthesis_Homo sapiens_hsa001200.28453540
151Insulin secretion_Homo sapiens_hsa049110.26167448
152Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.25655011
153Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.24987913
154Steroid hormone biosynthesis_Homo sapiens_hsa001400.23697281
155ABC transporters_Homo sapiens_hsa020100.22524269
156Carbon metabolism_Homo sapiens_hsa012000.20143592
157Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.20022360
158Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.19609198
159Retinol metabolism_Homo sapiens_hsa008300.18243369

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