SBSN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1multicellular organismal water homeostasis (GO:0050891)8.84417831
2sphingoid metabolic process (GO:0046519)8.74920980
3keratinocyte differentiation (GO:0030216)7.84800002
4keratinocyte proliferation (GO:0043616)7.66275594
5water homeostasis (GO:0030104)7.43468731
6long-chain fatty acid biosynthetic process (GO:0042759)7.22081057
7sphingosine metabolic process (GO:0006670)7.15675743
8diol metabolic process (GO:0034311)6.62384426
9regulation of transforming growth factor beta1 production (GO:0032908)6.39999443
10epidermal cell differentiation (GO:0009913)6.28746300
11regulation of cell proliferation involved in kidney development (GO:1901722)6.19723727
12peptide cross-linking (GO:0018149)6.14607359
13regulation of ruffle assembly (GO:1900027)5.86316855
14bundle of His cell to Purkinje myocyte communication (GO:0086069)5.77800259
15positive regulation of glomerulus development (GO:0090193)5.63342224
16positive regulation of interleukin-8 secretion (GO:2000484)5.58988973
17hair cycle (GO:0042633)5.57640038
18molting cycle (GO:0042303)5.57640038
19fatty acid elongation (GO:0030497)5.56653820
20linoleic acid metabolic process (GO:0043651)5.39453738
21epidermis development (GO:0008544)5.29750355
22regulation of phospholipase A2 activity (GO:0032429)5.22411239
23detection of bacterium (GO:0016045)5.12099421
24glucosamine-containing compound catabolic process (GO:1901072)5.09399465
25intermediate filament organization (GO:0045109)4.96694989
26skin morphogenesis (GO:0043589)4.90454081
27chemical homeostasis within a tissue (GO:0048875)4.59403044
28lipoxygenase pathway (GO:0019372)4.53368798
29cyclooxygenase pathway (GO:0019371)4.47154840
30gap junction assembly (GO:0016264)4.39473216
31detection of other organism (GO:0098543)4.32497671
32G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.25419844
33interferon-gamma secretion (GO:0072643)4.23627451
34long-chain fatty-acyl-CoA metabolic process (GO:0035336)4.23611451
35hemidesmosome assembly (GO:0031581)4.21058135
36phosphatidylserine metabolic process (GO:0006658)4.19528494
37phospholipid scrambling (GO:0017121)4.18410620
38phosphatidylinositol acyl-chain remodeling (GO:0036149)4.14407589
39positive regulation of monocyte chemotaxis (GO:0090026)4.12536743
40regulation of interleukin-8 secretion (GO:2000482)4.09703172
41regulation of chemokine secretion (GO:0090196)4.02353515
42epithelium development (GO:0060429)3.93027140
43viral transcription (GO:0019083)3.90653927
44detection of external biotic stimulus (GO:0098581)3.88661702
45positive regulation of epidermal cell differentiation (GO:0045606)3.87935354
46regulation of glomerulus development (GO:0090192)3.87883531
47negative regulation of stress fiber assembly (GO:0051497)3.86529733
48positive regulation of epidermis development (GO:0045684)3.85596750
49ceramide biosynthetic process (GO:0046513)3.71851874
50ectoderm development (GO:0007398)3.71259196
51negative regulation of keratinocyte proliferation (GO:0010839)3.71042571
52cardiolipin metabolic process (GO:0032048)3.68468074
53prostaglandin biosynthetic process (GO:0001516)3.67866715
54prostanoid biosynthetic process (GO:0046457)3.67866715
55surfactant homeostasis (GO:0043129)3.66795357
56translational termination (GO:0006415)3.64675111
57sequestering of metal ion (GO:0051238)3.64179885
58regulation of hypersensitivity (GO:0002883)3.62881906
59negative regulation of interleukin-17 production (GO:0032700)3.58995172
60phosphatidylserine acyl-chain remodeling (GO:0036150)3.54049313
61keratinocyte development (GO:0003334)3.52517601
62fatty-acyl-CoA metabolic process (GO:0035337)3.47128578
63positive regulation of chemokine secretion (GO:0090197)3.44654210
64sphingolipid biosynthetic process (GO:0030148)3.43082005
65hair follicle morphogenesis (GO:0031069)3.41615646
66positive regulation of T cell chemotaxis (GO:0010820)3.36514094
67regulation of T cell chemotaxis (GO:0010819)3.36514094
68alditol phosphate metabolic process (GO:0052646)3.34454232
69ribosomal small subunit biogenesis (GO:0042274)3.31914298
70detection of biotic stimulus (GO:0009595)3.30915338
71phosphatidylglycerol acyl-chain remodeling (GO:0036148)3.30880448
72phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.29697835
73regulation of natural killer cell differentiation (GO:0032823)3.24558223
74phospholipid catabolic process (GO:0009395)3.22761676
75phospholipid efflux (GO:0033700)3.22088478
76negative regulation of interferon-gamma production (GO:0032689)3.20675445
77regulation of keratinocyte differentiation (GO:0045616)3.17864163
78regulation of monocyte chemotaxis (GO:0090025)3.15996305
79positive regulation of keratinocyte differentiation (GO:0045618)3.14262998
80positive regulation of transforming growth factor beta production (GO:0071636)3.12751827
81defense response to fungus (GO:0050832)3.11369596
82intermediate filament cytoskeleton organization (GO:0045104)3.07574060
83negative regulation of kidney development (GO:0090185)3.05612002
84transepithelial transport (GO:0070633)3.02834199
85unsaturated fatty acid biosynthetic process (GO:0006636)3.02247348
86intermediate filament-based process (GO:0045103)3.01518345
87positive regulation of cell cycle checkpoint (GO:1901978)2.99726612
88planar cell polarity pathway involved in neural tube closure (GO:0090179)2.98756005
89positive regulation of cholesterol efflux (GO:0010875)2.98599303
90phosphatidylcholine acyl-chain remodeling (GO:0036151)2.98384069
91prostanoid metabolic process (GO:0006692)2.97457599
92prostaglandin metabolic process (GO:0006693)2.97457599
93regulation of glomerular filtration (GO:0003093)2.96245455
94chemosensory behavior (GO:0007635)2.95750938
95gland morphogenesis (GO:0022612)2.93626428
96viral life cycle (GO:0019058)2.93117322
97regulation of epidermis development (GO:0045682)2.92783829
98response to UV-B (GO:0010224)2.92715921
99negative regulation of acute inflammatory response (GO:0002674)2.90665759
100phosphatidylglycerol metabolic process (GO:0046471)2.88578655
101SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.88253319
102protein targeting to ER (GO:0045047)2.85794320
103negative regulation of interleukin-2 production (GO:0032703)2.85203476
104polarized epithelial cell differentiation (GO:0030859)2.83891534
105cotranslational protein targeting to membrane (GO:0006613)2.83462994
106eyelid development in camera-type eye (GO:0061029)2.83301787
107translational elongation (GO:0006414)2.82328035
108establishment of protein localization to endoplasmic reticulum (GO:0072599)2.81476348
109positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.80579619
110regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.78924819
111epithelial cell differentiation (GO:0030855)2.78207139
112regulation of keratinocyte proliferation (GO:0010837)2.78179544
113positive regulation of mitochondrial membrane permeability (GO:0035794)2.77529727
114primary alcohol catabolic process (GO:0034310)2.77450502
115response to phenylpropanoid (GO:0080184)2.76490676
116retinal metabolic process (GO:0042574)2.76365254
117cellular protein complex disassembly (GO:0043624)2.76301043
118arachidonic acid secretion (GO:0050482)2.75833400
119icosanoid secretion (GO:0032309)2.75833400
120establishment of tissue polarity (GO:0007164)2.75391994
121establishment of planar polarity (GO:0001736)2.75391994
122negative regulation of T cell mediated immunity (GO:0002710)2.74575651
123negative regulation of actin filament bundle assembly (GO:0032232)2.73799241
124epithelial cell differentiation involved in prostate gland development (GO:0060742)2.73512524
125negative regulation of cell fate specification (GO:0009996)2.73154404
126regulation of natural killer cell activation (GO:0032814)2.71498022
127ventricular cardiac muscle cell action potential (GO:0086005)2.71089943
128regulation of epidermal cell differentiation (GO:0045604)2.69116062
129lateral sprouting from an epithelium (GO:0060601)2.67256741
130skin development (GO:0043588)2.50423599
131atrioventricular valve morphogenesis (GO:0003181)2.49915013
132regulation of cholesterol homeostasis (GO:2000188)2.45235669
133myelin maintenance (GO:0043217)2.45142932
134regulation of axon regeneration (GO:0048679)2.43263042
135regulation of neuron projection regeneration (GO:0070570)2.43263042
136phosphatidic acid biosynthetic process (GO:0006654)2.42949156
137phosphatidic acid metabolic process (GO:0046473)2.42949156
138hair cycle process (GO:0022405)2.38399958
139molting cycle process (GO:0022404)2.38399958
140regulation of heart rate by cardiac conduction (GO:0086091)2.36721835
141negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.35591246
142epithelial cell-cell adhesion (GO:0090136)2.34204938
143defense response to Gram-negative bacterium (GO:0050829)2.26639895
144cell communication involved in cardiac conduction (GO:0086065)2.21736209
145one-carbon compound transport (GO:0019755)2.20801864
146regulation of hair cycle (GO:0042634)2.19183667
147cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.18592085
148retinol metabolic process (GO:0042572)2.18056575
149positive regulation of cellular amide metabolic process (GO:0034250)2.15252837
150desmosome organization (GO:0002934)15.0955435
151establishment of skin barrier (GO:0061436)14.7094489
152regulation of water loss via skin (GO:0033561)13.1612948
153keratinization (GO:0031424)11.1863700

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse6.55883724
2* P63_26484246_Chip-Seq_KERATINOCYTES_Human3.25779961
3SOX9_24532713_ChIP-Seq_HFSC_Mouse2.92409007
4ESR1_21235772_ChIP-Seq_MCF-7_Human2.65059383
5SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.40939349
6ESR2_21235772_ChIP-Seq_MCF-7_Human2.33214341
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.30803011
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.11912904
9TP63_17297297_ChIP-ChIP_HaCaT_Human14.6805916
10SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.94975112
11SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.94975112
12FOXO3_23340844_ChIP-Seq_DLD1_Human1.93784744
13STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82582476
14ZNF263_19887448_ChIP-Seq_K562_Human1.77331439
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.70831577
16TCF4_18268006_ChIP-ChIP_LS174T_Human1.69794240
17SOX2_20726797_ChIP-Seq_SW620_Human1.68770505
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.64437795
19ZNF217_24962896_ChIP-Seq_MCF-7_Human1.62761104
20ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.60206377
21TP63_23658742_ChIP-Seq_EP156T_Human1.60157723
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.58768227
23EGR1_19032775_ChIP-ChIP_M12_Human1.58605265
24SRY_22984422_ChIP-ChIP_TESTIS_Rat1.57545314
25BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.42050370
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.38378500
27TP53_18474530_ChIP-ChIP_U2OS_Human1.38188891
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.35108786
29TP63_22573176_ChIP-Seq_HFKS_Human1.34894158
30ERG_20517297_ChIP-Seq_VCAP_Human1.33559291
31GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.31746195
32CJUN_26792858_Chip-Seq_BT549_Human1.29738505
33RUNX1_27514584_Chip-Seq_MCF-7_Human1.28470621
34KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27313992
35HIF1A_21447827_ChIP-Seq_MCF-7_Human1.24937341
36SMC4_20622854_ChIP-Seq_HELA_Human1.23788803
37GATA4_25053715_ChIP-Seq_YYC3_Human1.20838763
38KLF5_25053715_ChIP-Seq_YYC3_Human1.20629732
39GATA3_24758297_ChIP-Seq_MCF-7_Human1.20329288
40E2F1_20622854_ChIP-Seq_HELA_Human1.19944372
41BCOR_27268052_Chip-Seq_Bcells_Human1.16854654
42CTCF_20526341_ChIP-Seq_ESCs_Human1.13506118
43STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.12460889
44GATA6_21074721_ChIP-Seq_CACO-2_Human1.12150917
45AR_21572438_ChIP-Seq_LNCaP_Human1.12056021
46RXR_22108803_ChIP-Seq_LS180_Human1.10312296
47CLOCK_20551151_ChIP-Seq_293T_Human1.09948378
48CEBPB_22108803_ChIP-Seq_LS180_Human1.08910083
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.08471040
50ATF3_27146783_Chip-Seq_COLON_Human1.01865329
51KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.01601366
52RARG_19884340_ChIP-ChIP_MEFs_Mouse1.01126144
53ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.00911610
54CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.99618561
55BCAT_22108803_ChIP-Seq_LS180_Human0.98373878
56TCF4_22108803_ChIP-Seq_LS180_Human0.96228577
57RACK7_27058665_Chip-Seq_MCF-7_Human0.96009244
58SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.92987401
59SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.91707372
60SUZ12_27294783_Chip-Seq_ESCs_Mouse0.91690891
61UBF1/2_26484160_Chip-Seq_HMECs_Human0.90973187
62CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.89938218
63BCL6_27268052_Chip-Seq_Bcells_Human0.89771930
64CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89503785
65AHR_22903824_ChIP-Seq_MCF-7_Human0.89441892
66RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.87912219
67P68_20966046_ChIP-Seq_HELA_Human0.87535372
68CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.86692432
69VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.86428433
70EZH2_27304074_Chip-Seq_ESCs_Mouse0.85496962
71SA1_27219007_Chip-Seq_ERYTHROID_Human0.85086229
72P53_21459846_ChIP-Seq_SAOS-2_Human0.85026946
73FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84590098
74LXR_22292898_ChIP-Seq_THP-1_Human0.84479070
75* TP53_20018659_ChIP-ChIP_R1E_Mouse0.84173788
76GATA6_25053715_ChIP-Seq_YYC3_Human0.83662522
77EED_16625203_ChIP-ChIP_MESCs_Mouse0.83437381
78PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.83267493
79P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.82125389
80PPAR_26484153_Chip-Seq_NCI-H1993_Human0.81505643
81EZH2_27294783_Chip-Seq_ESCs_Mouse0.80460052
82RBPJ_21746931_ChIP-Seq_IB4_Human0.80449693
83BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80036778
84ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.79116420
85FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.79051467
86FOXM1_26456572_ChIP-Seq_MCF-7_Human0.78916437
87SOX2_27498859_Chip-Seq_STOMACH_Mouse0.78832491
88YY1_22570637_ChIP-Seq_MALME-3M_Human0.77098354
89AUTS2_25519132_ChIP-Seq_293T-REX_Human0.75919114
90KDM2B_26808549_Chip-Seq_K562_Human0.75786289
91* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75582862
92P300_27058665_Chip-Seq_ZR-75-30cells_Human0.75218049
93BMI1_23680149_ChIP-Seq_NPCS_Mouse0.74947556
94CDX2_20551321_ChIP-Seq_CACO-2_Human0.74694310
95SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.74500318
96FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.73672120
97HNFA_21074721_ChIP-Seq_CACO-2_Human0.73670147
98* CTCF_27219007_Chip-Seq_Bcells_Human0.72720937
99JARID2_20075857_ChIP-Seq_MESCs_Mouse0.71966218
100FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.71326640
101PPARA_22158963_ChIP-Seq_LIVER_Mouse0.71269487
102AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.70672763
103RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.69854773
104GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.69408397
105DNAJC2_21179169_ChIP-ChIP_NT2_Human0.69031655
106SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.68805181
107* SA1_27219007_Chip-Seq_Bcells_Human0.68580702
108KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.68542455
109TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.68526158
110KDM2B_26808549_Chip-Seq_SUP-B15_Human0.68422654
111SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.68018200
112P300_27268052_Chip-Seq_Bcells_Human0.67739172
113UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.67596224
114SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.67568225
115FOXA1_27270436_Chip-Seq_PROSTATE_Human0.67195157
116FOXA1_25329375_ChIP-Seq_VCAP_Human0.67195157
117ERG_21242973_ChIP-ChIP_JURKAT_Human0.66963420
118TAF2_19829295_ChIP-Seq_ESCs_Human0.66534137
119ARNT_22903824_ChIP-Seq_MCF-7_Human0.66362114
120SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.66324267
121GATA3_21867929_ChIP-Seq_TH1_Mouse0.66089993
122KDM2B_26808549_Chip-Seq_JURKAT_Human0.66003740
123RNF2_27304074_Chip-Seq_ESCs_Mouse0.65603147
124TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.65461088
125ESR1_20079471_ChIP-ChIP_T-47D_Human0.65247576
126THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.65145320
127SMAD4_21741376_ChIP-Seq_ESCs_Human0.64367978
128NANOG_20526341_ChIP-Seq_ESCs_Human0.64006521
129CBX2_22325352_ChIP-Seq_293T-Rex_Human0.63793397
130SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.63535265
131KDM2B_26808549_Chip-Seq_DND41_Human0.63083576
132RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.62983617
133FOXA1_21572438_ChIP-Seq_LNCaP_Human0.62446636
134ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.61856928
135* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.61766185
136JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.61761791
137EZH2_18974828_ChIP-Seq_MESCs_Mouse0.61636286

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.47456187
2MP0010234_abnormal_vibrissa_follicle6.76070744
3MP0003941_abnormal_skin_development6.03669935
4MP0005275_abnormal_skin_tensile5.83443423
5MP0005501_abnormal_skin_physiology5.32641098
6MP0005451_abnormal_body_composition4.13480410
7MP0004381_abnormal_hair_follicle4.10663428
8MP0002060_abnormal_skin_morphology3.40907117
9MP0001216_abnormal_epidermal_layer3.39021726
10MP0010771_integument_phenotype3.18770812
11MP0000579_abnormal_nail_morphology3.00706917
12MP0003453_abnormal_keratinocyte_physiol2.91964113
13MP0002098_abnormal_vibrissa_morphology2.89902921
14MP0010678_abnormal_skin_adnexa2.85871943
15MP0004947_skin_inflammation2.75119467
16MP0000647_abnormal_sebaceous_gland2.52817680
17MP0000377_abnormal_hair_follicle2.34750962
18MP0005409_darkened_coat_color2.29895206
19MP0000383_abnormal_hair_follicle2.28720004
20MP0002254_reproductive_system_inflammat2.27865213
21MP0001188_hyperpigmentation2.25903523
22MP0004885_abnormal_endolymph2.23337558
23MP0005377_hearing/vestibular/ear_phenot2.10241967
24MP0003878_abnormal_ear_physiology2.10241967
25MP0000566_synostosis1.99255569
26MP0000427_abnormal_hair_cycle1.97181356
27MP0000467_abnormal_esophagus_morphology1.94485032
28MP0003191_abnormal_cellular_cholesterol1.80075484
29MP0002009_preneoplasia1.76199383
30MP0009931_abnormal_skin_appearance1.72140570
31MP0001191_abnormal_skin_condition1.67858905
32MP0004185_abnormal_adipocyte_glucose1.67465956
33MP0003705_abnormal_hypodermis_morpholog1.55155681
34MP0003566_abnormal_cell_adhesion1.49032925
35MP0009379_abnormal_foot_pigmentation1.40650574
36MP0001243_abnormal_dermal_layer1.35872567
37MP0000762_abnormal_tongue_morphology1.34795700
38MP0000367_abnormal_coat/_hair1.32603681
39MP0001346_abnormal_lacrimal_gland1.28737045
40MP0003011_delayed_dark_adaptation1.18520550
41MP0004782_abnormal_surfactant_physiolog1.10876068
42MP0008004_abnormal_stomach_pH1.04442150
43MP0000465_gastrointestinal_hemorrhage0.97385843
44MP0001851_eye_inflammation0.96187149
45MP0001340_abnormal_eyelid_morphology0.91425301
46MP0000015_abnormal_ear_pigmentation0.87649035
47MP0010352_gastrointestinal_tract_polyps0.86002741
48MP0001984_abnormal_olfaction0.83614699
49MP0010386_abnormal_urinary_bladder0.80650231
50MP0006054_spinal_hemorrhage0.78841965
51MP0005174_abnormal_tail_pigmentation0.78114469
52MP0003315_abnormal_perineum_morphology0.69586767
53MP0003136_yellow_coat_color0.65781029
54MP0003950_abnormal_plasma_membrane0.64202832
55MP0004043_abnormal_pH_regulation0.63294660
56MP0005075_abnormal_melanosome_morpholog0.62717684
57MP0000516_abnormal_urinary_system0.60166022
58MP0005367_renal/urinary_system_phenotyp0.60166022
59MP0002877_abnormal_melanocyte_morpholog0.59172659
60MP0001784_abnormal_fluid_regulation0.58956525
61MP0002234_abnormal_pharynx_morphology0.57574936
62MP0002006_tumorigenesis0.56274778
63MP0004019_abnormal_vitamin_homeostasis0.55941752
64MP0002177_abnormal_outer_ear0.54946062
65MP0005076_abnormal_cell_differentiation0.53483484
66MP0005023_abnormal_wound_healing0.53345644
67MP0002166_altered_tumor_susceptibility0.53246566
68MP0004264_abnormal_extraembryonic_tissu0.52110077
69MP0009053_abnormal_anal_canal0.50344442
70MP0000627_abnormal_mammary_gland0.49544449
71MP0002249_abnormal_larynx_morphology0.45282039
72MP0003300_gastrointestinal_ulcer0.44548781
73MP0005666_abnormal_adipose_tissue0.44519530
74MP0009384_cardiac_valve_regurgitation0.41958146
75MP0002090_abnormal_vision0.41528096
76MP0008961_abnormal_basal_metabolism0.40447013
77MP0000537_abnormal_urethra_morphology0.39560157
78MP0003436_decreased_susceptibility_to0.38305583
79MP0005508_abnormal_skeleton_morphology0.38102967
80MP0001177_atelectasis0.37093085
81MP0003638_abnormal_response/metabolism_0.36449606
82MP0002111_abnormal_tail_morphology0.34828575
83MP0003755_abnormal_palate_morphology0.34266853
84MP0000538_abnormal_urinary_bladder0.33968712
85MP0005187_abnormal_penis_morphology0.33575835
86MP0002277_abnormal_respiratory_mucosa0.33549885
87MP0009780_abnormal_chondrocyte_physiolo0.33356851
88MP0010030_abnormal_orbit_morphology0.33143260
89MP0003329_amyloid_beta_deposits0.31402627
90MP0003763_abnormal_thymus_physiology0.30833067
91MP0005375_adipose_tissue_phenotype0.30667113
92MP0008438_abnormal_cutaneous_collagen0.29535950
93MP0009333_abnormal_splenocyte_physiolog0.28848636
94MP0004272_abnormal_basement_membrane0.27810632
95MP0002148_abnormal_hypersensitivity_rea0.27328732
96MP0000685_abnormal_immune_system0.25363062
97MP0001542_abnormal_bone_strength0.25361226
98MP0002095_abnormal_skin_pigmentation0.24928902
99MP0001186_pigmentation_phenotype0.24869484
100MP0008789_abnormal_olfactory_epithelium0.24835230
101MP0002282_abnormal_trachea_morphology0.24677846
102MP0000013_abnormal_adipose_tissue0.24094675
103MP0005388_respiratory_system_phenotype0.22317505
104MP0002133_abnormal_respiratory_system0.22317505
105MP0005257_abnormal_intraocular_pressure0.22076580
106MP0005394_taste/olfaction_phenotype0.21041954
107MP0005499_abnormal_olfactory_system0.21041954
108MP0008260_abnormal_autophagy0.20811402
109MP0005503_abnormal_tendon_morphology0.20596516
110MP0002233_abnormal_nose_morphology0.20270416
111MP0005390_skeleton_phenotype0.17891133
112MP0000432_abnormal_head_morphology0.17832917
113MP0000470_abnormal_stomach_morphology0.16917392
114MP0003385_abnormal_body_wall0.16761480
115MP0002697_abnormal_eye_size0.16578346
116MP0008569_lethality_at_weaning0.15518364
117MP0001666_abnormal_nutrient_absorption0.15413668
118MP0004197_abnormal_fetal_growth/weight/0.15394848
119MP0001765_abnormal_ion_homeostasis0.14191265
120MP0003938_abnormal_ear_development0.14120212
121MP0009250_abnormal_appendicular_skeleto0.13973005
122MP0005193_abnormal_anterior_eye0.13716022
123MP0001299_abnormal_eye_distance/0.13696281
124MP0001485_abnormal_pinna_reflex0.13680540
125MP0003195_calcinosis0.13001486
126MP0003448_altered_tumor_morphology0.12157031
127MP0001958_emphysema0.12077013
128MP0004510_myositis0.11121904
129MP0001502_abnormal_circadian_rhythm0.10265786
130MP0009840_abnormal_foam_cell0.10210667
131MP0000858_altered_metastatic_potential0.08847042
132MP0002075_abnormal_coat/hair_pigmentati0.07357289

Predicted human phenotypes

RankGene SetZ-score
1Congenital nonbullous ichthyosiform erythroderma (HP:0007479)9.77579993
2Congenital ichthyosiform erythroderma (HP:0007431)9.34918721
3Increased IgE level (HP:0003212)7.91667149
4Oral leukoplakia (HP:0002745)7.42834012
5Hypotrichosis (HP:0001006)7.24828372
6Parakeratosis (HP:0001036)6.82349412
7Abnormality of nail color (HP:0100643)6.56772237
8Erythema (HP:0010783)6.26115990
9Woolly hair (HP:0002224)6.20719429
10Erythroderma (HP:0001019)6.13715576
11Right ventricular cardiomyopathy (HP:0011663)5.97637234
12Lip pit (HP:0100267)5.76637544
13Palmoplantar hyperkeratosis (HP:0000972)5.61226477
14Plantar hyperkeratosis (HP:0007556)5.34753416
15Palmar hyperkeratosis (HP:0010765)5.26712899
16Ectropion (HP:0000656)4.86459877
17Gangrene (HP:0100758)4.63428509
18Corneal erosion (HP:0200020)4.41703870
19Onycholysis (HP:0001806)4.37072572
20Follicular hyperkeratosis (HP:0007502)4.34835323
21Abnormality of secondary sexual hair (HP:0009888)4.09783572
22Abnormality of the axillary hair (HP:0100134)4.09783572
23Hypohidrosis (HP:0000966)4.06323037
24Natal tooth (HP:0000695)4.04496021
25Sparse scalp hair (HP:0002209)3.99912695
26Conjunctival hamartoma (HP:0100780)3.96826973
27Pruritus (HP:0000989)3.79009026
28Fragile nails (HP:0001808)3.72488174
29Hyporeflexia of lower limbs (HP:0002600)3.71181129
30Abnormal blistering of the skin (HP:0008066)3.63771766
31Palmoplantar keratoderma (HP:0000982)3.57198357
32Popliteal pterygium (HP:0009756)3.47108490
33Absent eyelashes (HP:0000561)3.40712058
34Curly hair (HP:0002212)3.36466678
35Sparse eyelashes (HP:0000653)3.34292015
36Acanthosis nigricans (HP:0000956)3.30676893
37Advanced eruption of teeth (HP:0006288)3.30637408
38Pili torti (HP:0003777)3.13350534
39Ventricular tachycardia (HP:0004756)3.00923042
40Nail dystrophy (HP:0008404)2.94715138
41Absent hair (HP:0002298)2.94629167
42Distal lower limb muscle weakness (HP:0009053)2.91062755
43Lack of skin elasticity (HP:0100679)2.86744278
44Dry skin (HP:0000958)2.80398087
45Abnormality of the salivary glands (HP:0010286)2.71772011
46Hypoplastic labia majora (HP:0000059)2.65835456
47Brittle hair (HP:0002299)2.64369148
48Concave nail (HP:0001598)2.61826685
49Laryngomalacia (HP:0001601)2.61041027
50Thick nail (HP:0001805)2.60621267
51Dehydration (HP:0001944)2.60332598
52Axonal loss (HP:0003447)2.60073439
53Areflexia of lower limbs (HP:0002522)2.57672573
54Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.56909793
55Furrowed tongue (HP:0000221)2.54596744
56Congenital, generalized hypertrichosis (HP:0004540)2.48295767
57Hypergammaglobulinemia (HP:0010702)2.45429072
58Abnormality of placental membranes (HP:0011409)2.40195177
59Amniotic constriction ring (HP:0009775)2.40195177
60Abnormality of the labia majora (HP:0012881)2.40053215
61Milia (HP:0001056)2.34424298
62Oligodontia (HP:0000677)2.27229511
63Hamartoma of the eye (HP:0010568)2.21288215
64Severe Myopia (HP:0011003)2.21062680
65Ventricular fibrillation (HP:0001663)2.20966214
66Abnormality of hair growth rate (HP:0011363)2.18676130
67Slow-growing hair (HP:0002217)2.18676130
68Villous atrophy (HP:0011473)2.18099096
69Abnormality of small intestinal villus morphology (HP:0011472)2.18099096
70Segmental peripheral demyelination/remyelination (HP:0003481)2.14856506
71Malignant hyperthermia (HP:0002047)2.14591871
72Anhidrosis (HP:0000970)2.10722661
73Eczematoid dermatitis (HP:0000976)2.09134415
74Abnormality of cells of the erythroid lineage (HP:0012130)2.08508004
75Abnormality of the gastric mucosa (HP:0004295)2.06047099
76Anonychia (HP:0001798)2.04342822
77Autoamputation (HP:0001218)2.03126398
78Reticulocytopenia (HP:0001896)2.02989534
79Paralysis (HP:0003470)2.00800715
80Multifactorial inheritance (HP:0001426)2.00510706
81Premature ovarian failure (HP:0008209)2.00152580
82Abnormal hemoglobin (HP:0011902)1.98569164
83Dry hair (HP:0011359)1.97232344
84Pterygium (HP:0001059)1.94597072
85Septate vagina (HP:0001153)1.93278589
86Abnormal hair laboratory examination (HP:0003328)1.93093519
87Pustule (HP:0200039)1.90414182
88Sepsis (HP:0100806)1.82866217
89Melanocytic nevus (HP:0000995)1.81099237
90Corneal dystrophy (HP:0001131)1.79753302
91Ridged nail (HP:0001807)1.77063446
92Verrucae (HP:0200043)1.75385652
93Papilloma (HP:0012740)1.75385652
94Recurrent corneal erosions (HP:0000495)1.74986859
95Stenosis of the external auditory canal (HP:0000402)1.73614704
96Urticaria (HP:0001025)1.72995420
97Labial hypoplasia (HP:0000066)1.71828915
98Blepharitis (HP:0000498)1.69262047
99Carious teeth (HP:0000670)1.68731468
100Ulnar claw (HP:0001178)1.67755711
101Skin pits (HP:0100276)1.61852974
102Abnormal number of erythroid precursors (HP:0012131)1.61192165
103Down-sloping shoulders (HP:0200021)1.60738534
104Fatigable weakness (HP:0003473)1.58769989
105Abnormality of the neuromuscular junction (HP:0003398)1.58769989
106Skin ulcer (HP:0200042)1.57966741
107Abnormality of the fingernails (HP:0001231)1.57810581
108Fasciculations (HP:0002380)1.57540281
109Neonatal death (HP:0003811)1.57483918
110Bifid scrotum (HP:0000048)1.56995630
111Hypodontia (HP:0000668)1.56127875
112Fine hair (HP:0002213)1.55872125
113Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.55749890
114Abnormal auditory evoked potentials (HP:0006958)1.54452746
115Selective tooth agenesis (HP:0001592)1.54010829
116Alopecia of scalp (HP:0002293)1.53266627
117Macrocytic anemia (HP:0001972)1.52791564
118Hypoplastic female external genitalia (HP:0012815)1.52175548
119Epidermoid cyst (HP:0200040)1.50812077
120Achilles tendon contracture (HP:0001771)1.50526414
121Hamartoma (HP:0010566)1.50007608
122Keratoconjunctivitis sicca (HP:0001097)1.48716781
123Everted lower lip vermilion (HP:0000232)1.47870801
124Asthma (HP:0002099)1.47191132
125Chronic bronchitis (HP:0004469)1.46005339
126Conical tooth (HP:0000698)1.44027252
127Trismus (HP:0000211)1.43749366
128Xerostomia (HP:0000217)1.41667341
129Sudden death (HP:0001699)1.41174105
130Hyperhidrosis (HP:0000975)1.40807009
131Absent eyebrow (HP:0002223)1.40341632
132Keratoconjunctivitis (HP:0001096)1.33565426
133Split foot (HP:0001839)1.30125125
134Abnormality of the dental root (HP:0006486)1.28722261
135Taurodontia (HP:0000679)1.28722261
136Abnormality of permanent molar morphology (HP:0011071)1.28722261
137Hypoplastic toenails (HP:0001800)1.23082730
138Abnormality of molar (HP:0011077)1.22498162
139Abnormality of molar morphology (HP:0011070)1.22498162

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK35.33893876
2MST1R4.43337701
3MST44.41226778
4MAP3K34.16877032
5TGFBR13.92381207
6FER3.47914175
7MAP3K23.37799901
8SGK4943.32646124
9SGK2233.32646124
10MAP3K92.81405497
11RPS6KB22.64399407
12PIM22.54988569
13EPHB22.49096605
14TESK12.27993305
15TRPM72.17360254
16LATS12.13674400
17EPHB12.12101868
18BCR1.85569560
19ERN11.81419108
20MAPKAPK51.74182307
21ERBB31.62503825
22PRPF4B1.59029461
23LIMK11.58098478
24LRRK21.54277118
25PIK3CG1.46866171
26STK241.43234155
27TNK21.41722087
28GRK61.40246271
29STK101.39671110
30PTK21.39431690
31IRAK11.38506346
32BLK1.35216950
33MET1.32612609
34DYRK1B1.27052485
35RIPK41.22743888
36ITK1.20031759
37GRK11.17329975
38GSK3A1.15176793
39PTK61.13808191
40MAP3K111.11566948
41MAPK71.09815583
42NTRK21.08476570
43FGFR21.07964344
44MAP2K61.02051985
45PRKD20.98354320
46TAOK10.98077299
47FGFR40.96726926
48MAP3K140.96319583
49STK30.92489638
50FGFR10.89840906
51CDK120.89292258
52EEF2K0.86121079
53LATS20.85843048
54BMX0.83991804
55MAP3K120.82789083
56MAP3K70.79447388
57JAK30.79447340
58TGFBR20.78041188
59GRK70.78033815
60CDK30.77349002
61MAPKAPK20.76314811
62SIK10.75797285
63TYRO30.75608799
64STK380.75302435
65EPHA20.74136796
66SGK10.73830528
67EPHA30.73423398
68CDK60.73277193
69MAPK120.71541400
70EPHA40.71134254
71CDK190.69000302
72MOS0.68558794
73GRK50.68363593
74MAP3K10.67532084
75IRAK30.66465244
76SYK0.66021592
77ADRBK10.65105728
78NLK0.64753770
79KSR20.64574228
80PAK30.64548061
81MAP3K130.64328889
82MAP3K60.64149977
83SRPK10.62580877
84ABL20.58840467
85TTN0.57442702
86MAP3K50.55796808
87BRAF0.55684799
88KIT0.55355117
89FGFR30.55209841
90NME20.53765756
91BMPR1B0.53069943
92PRKCE0.51769185
93RET0.51675299
94MAP2K40.50444798
95CASK0.49712552
96CSNK1D0.49018755
97PRKCI0.48703342
98MTOR0.47763904
99TRIB30.47084909
100RIPK10.47045145
101PRKD10.46272758
102SMG10.45928753
103ROCK10.45799361
104PBK0.45564418
105IRAK20.45273830
106PKN10.44889425
107IKBKE0.44422418
108CDC42BPA0.43603082
109OBSCN0.43215368
110EIF2AK20.43138643
111SGK30.42299451
112WNK10.42124208
113RPS6KB10.41015807
114PRKAA20.40799422
115ILK0.40616160
116MAP2K30.39973111
117BMPR20.39292264
118STK110.38821210
119PDGFRB0.37632865
120ICK0.36917270
121STK38L0.36617241
122IKBKB0.35272179
123YES10.35229657
124TAOK20.35152386
125RPS6KA10.33414279
126AURKA0.32806543
127ABL10.31982156
128DMPK0.31016472
129TEC0.30881913
130SGK20.29962794
131MAP2K10.29859095
132ERBB20.29270967
133ARAF0.27608969
134SRC0.27185846
135MARK20.27051024
136MAPK40.26525242
137HIPK20.26181405
138IRAK40.25923326
139FGR0.25686016
140JAK20.25179223
141TYK20.24980061
142PDGFRA0.23793743
143HCK0.22515179
144BTK0.22447449
145PAK20.21219011
146DDR20.19811385
147RPS6KA20.19749388

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004604.93196575
2Sphingolipid metabolism_Homo sapiens_hsa006004.83575524
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.21666381
4Linoleic acid metabolism_Homo sapiens_hsa005913.68674814
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.62441050
6Arachidonic acid metabolism_Homo sapiens_hsa005903.52454463
7Ribosome_Homo sapiens_hsa030103.25003444
8Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.20153907
9Fatty acid elongation_Homo sapiens_hsa000623.15402613
10Ether lipid metabolism_Homo sapiens_hsa005652.28614599
11Histidine metabolism_Homo sapiens_hsa003402.16710790
12Retinol metabolism_Homo sapiens_hsa008301.85439468
13Phenylalanine metabolism_Homo sapiens_hsa003601.82925845
14Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.57337791
15Sphingolipid signaling pathway_Homo sapiens_hsa040711.49727628
16Tight junction_Homo sapiens_hsa045301.49057786
17ABC transporters_Homo sapiens_hsa020101.47837112
18Circadian rhythm_Homo sapiens_hsa047101.43865670
19Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.37894580
20Collecting duct acid secretion_Homo sapiens_hsa049661.30636343
21VEGF signaling pathway_Homo sapiens_hsa043701.29064160
22Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.27115062
23Serotonergic synapse_Homo sapiens_hsa047261.20708353
24Adherens junction_Homo sapiens_hsa045201.20476744
25Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.20095675
26Axon guidance_Homo sapiens_hsa043601.18922535
27Basal cell carcinoma_Homo sapiens_hsa052171.17834630
28Choline metabolism in cancer_Homo sapiens_hsa052311.14735969
29Fat digestion and absorption_Homo sapiens_hsa049751.13298686
30Chemical carcinogenesis_Homo sapiens_hsa052041.09938618
31Staphylococcus aureus infection_Homo sapiens_hsa051501.09366744
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98343811
33Tyrosine metabolism_Homo sapiens_hsa003500.94578619
34p53 signaling pathway_Homo sapiens_hsa041150.91035967
35Renin secretion_Homo sapiens_hsa049240.90208124
36Acute myeloid leukemia_Homo sapiens_hsa052210.88215042
37Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87548443
38Dorso-ventral axis formation_Homo sapiens_hsa043200.87221395
39GnRH signaling pathway_Homo sapiens_hsa049120.87049111
40Melanogenesis_Homo sapiens_hsa049160.86728301
41Pancreatic secretion_Homo sapiens_hsa049720.85469569
42SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84901777
43Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84572170
44Glycerophospholipid metabolism_Homo sapiens_hsa005640.84308173
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.82737724
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.82336365
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80386533
48Hippo signaling pathway_Homo sapiens_hsa043900.79448674
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79083235
50Ras signaling pathway_Homo sapiens_hsa040140.77349290
51Glutathione metabolism_Homo sapiens_hsa004800.77201156
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.76339082
53Fatty acid biosynthesis_Homo sapiens_hsa000610.75150691
54Phototransduction_Homo sapiens_hsa047440.75100089
55Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.75084400
56Caffeine metabolism_Homo sapiens_hsa002320.73208311
57Mineral absorption_Homo sapiens_hsa049780.72545205
58Steroid biosynthesis_Homo sapiens_hsa001000.70293489
59Pertussis_Homo sapiens_hsa051330.69771127
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69254852
61Bladder cancer_Homo sapiens_hsa052190.68842785
62Proteoglycans in cancer_Homo sapiens_hsa052050.68181163
63Renal cell carcinoma_Homo sapiens_hsa052110.67375831
64Hepatitis C_Homo sapiens_hsa051600.67291045
65HIF-1 signaling pathway_Homo sapiens_hsa040660.65718286
66Long-term depression_Homo sapiens_hsa047300.64401408
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.64217301
68ErbB signaling pathway_Homo sapiens_hsa040120.63539863
69Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62330770
70ECM-receptor interaction_Homo sapiens_hsa045120.58816319
71Fructose and mannose metabolism_Homo sapiens_hsa000510.58797121
72Platelet activation_Homo sapiens_hsa046110.58308459
73Vibrio cholerae infection_Homo sapiens_hsa051100.57950685
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57103443
75Glioma_Homo sapiens_hsa052140.56541751
76Central carbon metabolism in cancer_Homo sapiens_hsa052300.55210505
77TGF-beta signaling pathway_Homo sapiens_hsa043500.53021825
78beta-Alanine metabolism_Homo sapiens_hsa004100.52844795
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.50820566
80MAPK signaling pathway_Homo sapiens_hsa040100.49971816
81Ovarian steroidogenesis_Homo sapiens_hsa049130.49849677
82MicroRNAs in cancer_Homo sapiens_hsa052060.48837443
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.46921150
84Gastric acid secretion_Homo sapiens_hsa049710.46192295
85NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45971794
86Olfactory transduction_Homo sapiens_hsa047400.45176544
87Hedgehog signaling pathway_Homo sapiens_hsa043400.45001963
88Insulin signaling pathway_Homo sapiens_hsa049100.43492884
89Tuberculosis_Homo sapiens_hsa051520.41723760
90Notch signaling pathway_Homo sapiens_hsa043300.41608044
91Wnt signaling pathway_Homo sapiens_hsa043100.40344447
92Rap1 signaling pathway_Homo sapiens_hsa040150.39514624
93Galactose metabolism_Homo sapiens_hsa000520.36854336
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36843372
95Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36719439
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.35875804
97Endocytosis_Homo sapiens_hsa041440.35338124
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34607742
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.34438070
100Oxytocin signaling pathway_Homo sapiens_hsa049210.34410144
101Melanoma_Homo sapiens_hsa052180.34329813
102Salmonella infection_Homo sapiens_hsa051320.33643868
103Inositol phosphate metabolism_Homo sapiens_hsa005620.32629682
104Malaria_Homo sapiens_hsa051440.32448564
105Thyroid cancer_Homo sapiens_hsa052160.32221832
106Lysosome_Homo sapiens_hsa041420.32152723
107Amoebiasis_Homo sapiens_hsa051460.31874467
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31786648
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31373271
110Influenza A_Homo sapiens_hsa051640.31282064
111Long-term potentiation_Homo sapiens_hsa047200.30770022
112Shigellosis_Homo sapiens_hsa051310.30459168
113Glutamatergic synapse_Homo sapiens_hsa047240.30375408
114Pancreatic cancer_Homo sapiens_hsa052120.30305997
115AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.30262133
116Glycerolipid metabolism_Homo sapiens_hsa005610.30049708
117Calcium signaling pathway_Homo sapiens_hsa040200.29099894
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.29011899
119Rheumatoid arthritis_Homo sapiens_hsa053230.28932692
120Pathways in cancer_Homo sapiens_hsa052000.26907835
121TNF signaling pathway_Homo sapiens_hsa046680.26761864
122Salivary secretion_Homo sapiens_hsa049700.26343250
123Estrogen signaling pathway_Homo sapiens_hsa049150.24691250
124Alzheimers disease_Homo sapiens_hsa050100.24447088
125Toxoplasmosis_Homo sapiens_hsa051450.24053429
126PPAR signaling pathway_Homo sapiens_hsa033200.23209371
127Nitrogen metabolism_Homo sapiens_hsa009100.22902175
128Phagosome_Homo sapiens_hsa041450.22813669
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.22219017
130Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.21760243
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.21609750
132Oxidative phosphorylation_Homo sapiens_hsa001900.21483030
133Other glycan degradation_Homo sapiens_hsa005110.21143381
134Aldosterone synthesis and secretion_Homo sapiens_hsa049250.21095656
135Taste transduction_Homo sapiens_hsa047420.20258500
136Focal adhesion_Homo sapiens_hsa045100.19171332
137Vitamin digestion and absorption_Homo sapiens_hsa049770.19149974

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