SCAF8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)4.95746718
2nuclear pore complex assembly (GO:0051292)4.92284197
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.89093702
4negative regulation of cell killing (GO:0031342)4.89093702
5regulation of RNA export from nucleus (GO:0046831)4.70835049
6nuclear pore organization (GO:0006999)4.65646717
7negative regulation of histone methylation (GO:0031061)4.22857030
8cytoplasmic mRNA processing body assembly (GO:0033962)4.22320210
9mitotic sister chromatid cohesion (GO:0007064)4.16748951
10regulation of nucleobase-containing compound transport (GO:0032239)4.04671506
11regulation of NFAT protein import into nucleus (GO:0051532)3.92403584
12positive thymic T cell selection (GO:0045059)3.86497313
13DNA unwinding involved in DNA replication (GO:0006268)3.82893894
14phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.78102625
15monoubiquitinated protein deubiquitination (GO:0035520)3.77970432
16glucocorticoid receptor signaling pathway (GO:0042921)3.72882008
17interkinetic nuclear migration (GO:0022027)3.72173358
18pore complex assembly (GO:0046931)3.70682830
19positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.57122017
20positive regulation of gamma-delta T cell activation (GO:0046645)3.56651183
21DNA duplex unwinding (GO:0032508)3.54846343
22DNA geometric change (GO:0032392)3.52893350
23regulation of sister chromatid cohesion (GO:0007063)3.52418383
24regulation of histone H3-K9 methylation (GO:0051570)3.46676634
25regulation of gamma-delta T cell differentiation (GO:0045586)3.46231508
26mitotic chromosome condensation (GO:0007076)3.43537338
27protein demethylation (GO:0006482)3.41231267
28protein localization to kinetochore (GO:0034501)3.37665660
29dosage compensation (GO:0007549)3.35609738
30mitotic nuclear envelope disassembly (GO:0007077)3.34528928
31positive regulation of DNA-templated transcription, initiation (GO:2000144)3.32894668
32regulation of histone H3-K27 methylation (GO:0061085)3.30351484
33definitive hemopoiesis (GO:0060216)3.29908661
34RNA stabilization (GO:0043489)3.26792322
35mRNA stabilization (GO:0048255)3.26792322
36heterochromatin organization (GO:0070828)3.26256239
37nuclear envelope disassembly (GO:0051081)3.25879211
38membrane disassembly (GO:0030397)3.25879211
39peptidyl-lysine dimethylation (GO:0018027)3.20701757
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.19009431
41positive T cell selection (GO:0043368)3.18282339
42histone H3-K9 methylation (GO:0051567)3.18248263
43positive regulation of histone deacetylation (GO:0031065)3.18050218
44histone H3-K9 modification (GO:0061647)3.17097668
45regulation of DNA damage checkpoint (GO:2000001)3.14767731
46negative T cell selection (GO:0043383)3.14186501
47negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.11338055
48negative thymic T cell selection (GO:0045060)3.08837775
49chromatin assembly (GO:0031497)3.07718730
50NLS-bearing protein import into nucleus (GO:0006607)3.06282635
51DNA synthesis involved in DNA repair (GO:0000731)3.04950722
52corticosteroid receptor signaling pathway (GO:0031958)3.04319511
53negative regulation of fibroblast apoptotic process (GO:2000270)3.03212579
54peptidyl-threonine phosphorylation (GO:0018107)3.02198920
55regulation of translational fidelity (GO:0006450)3.01730713
56sister chromatid cohesion (GO:0007062)3.00140401
57histone H3-K36 demethylation (GO:0070544)2.99633525
58regulation of gamma-delta T cell activation (GO:0046643)2.96027201
59positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.94594465
60regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.94594465
61histone H2A monoubiquitination (GO:0035518)2.92652380
62peptidyl-lysine methylation (GO:0018022)2.92142290
63regulation of DNA endoreduplication (GO:0032875)2.91909725
64embryonic process involved in female pregnancy (GO:0060136)2.91532791
65embryonic camera-type eye morphogenesis (GO:0048596)2.90960543
66histone H3-K4 methylation (GO:0051568)2.88042304
67thymic T cell selection (GO:0045061)2.86989034
68hippo signaling (GO:0035329)2.86427153
69protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.86426256
70nucleus localization (GO:0051647)2.86045247
71positive regulation of mitotic sister chromatid separation (GO:1901970)2.85675494
72positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.85675494
73positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.85675494
74histone H3-K9 demethylation (GO:0033169)2.84568861
75sister chromatid segregation (GO:0000819)2.83875042
76peptidyl-threonine modification (GO:0018210)2.83671715
77negative regulation of DNA repair (GO:0045738)2.82844341
78gene silencing by RNA (GO:0031047)2.82210776
79nuclear envelope organization (GO:0006998)2.81087710
80negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.80713943
81negative regulation of translation, ncRNA-mediated (GO:0040033)2.80713943
82regulation of translation, ncRNA-mediated (GO:0045974)2.80713943
83N-terminal protein amino acid acetylation (GO:0006474)2.78337906
84negative regulation of histone modification (GO:0031057)2.77608230
85genitalia morphogenesis (GO:0035112)2.77398071
86negative regulation of RNA splicing (GO:0033119)2.76818148
87protein K48-linked deubiquitination (GO:0071108)2.76738663
88positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.76253785
89histone H3-K4 trimethylation (GO:0080182)2.74683541
90positive regulation of SMAD protein import into nucleus (GO:0060391)2.73698356
91nucleus organization (GO:0006997)2.73642202
92mitotic G1 DNA damage checkpoint (GO:0031571)2.71834371
93regulation of mRNA stability (GO:0043488)2.71274983
94alternative mRNA splicing, via spliceosome (GO:0000380)2.70497041
95germ cell migration (GO:0008354)2.69403377
96regulation of protein polyubiquitination (GO:1902914)2.69244745
97protein localization to chromosome, centromeric region (GO:0071459)2.68522453
98regulation of gene silencing by RNA (GO:0060966)2.65905626
99regulation of posttranscriptional gene silencing (GO:0060147)2.65905626
100regulation of gene silencing by miRNA (GO:0060964)2.65905626
101histone H4-K16 acetylation (GO:0043984)2.65741626
102regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.64760275
103positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.64760275
104DNA conformation change (GO:0071103)2.64733433
105negative regulation of mRNA processing (GO:0050686)2.64518518
106histone lysine demethylation (GO:0070076)2.63998082
107Golgi to endosome transport (GO:0006895)2.63471137
108gene silencing (GO:0016458)2.62070185
109stress granule assembly (GO:0034063)2.61491271
110histone mRNA catabolic process (GO:0071044)2.61383092
111positive regulation of mRNA 3-end processing (GO:0031442)2.60850507
112regulation of histone methylation (GO:0031060)2.60826462
113regulation of histone H3-K4 methylation (GO:0051569)2.60399628
114positive regulation of chromosome segregation (GO:0051984)2.60333849
115positive regulation of RNA splicing (GO:0033120)2.60242710
116negative regulation of mRNA metabolic process (GO:1903312)2.59689794
117regulation of chromatin silencing (GO:0031935)2.59230673
118histone methylation (GO:0016571)2.58626066
119spliceosomal tri-snRNP complex assembly (GO:0000244)2.58209533
120determination of adult lifespan (GO:0008340)2.57984445
121negative regulation of chromatin modification (GO:1903309)2.57223585
122translesion synthesis (GO:0019985)2.54673497
123nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.54490366
124regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.54363723
125lipid translocation (GO:0034204)2.54204952
126phospholipid translocation (GO:0045332)2.54204952
127regulation of RNA stability (GO:0043487)2.53913160
128histone demethylation (GO:0016577)2.52780053
129regulation of centriole replication (GO:0046599)2.51608236
130regulation of fibroblast apoptotic process (GO:2000269)2.49084583
131histone H4-K8 acetylation (GO:0043982)2.48885302
132histone H4-K5 acetylation (GO:0043981)2.48885302
133T cell selection (GO:0045058)2.47833192
134histone lysine methylation (GO:0034968)2.47783093
135trophectodermal cell differentiation (GO:0001829)2.46879524
136positive regulation of gene expression, epigenetic (GO:0045815)2.46351699
137folic acid-containing compound biosynthetic process (GO:0009396)2.45901737
138protein export from nucleus (GO:0006611)2.45781211
139establishment of nucleus localization (GO:0040023)2.45202771
140peptidyl-lysine trimethylation (GO:0018023)2.45182034
141regulation of centrosome duplication (GO:0010824)2.44827042
142histone deubiquitination (GO:0016578)2.43927946
143regulation of mitotic spindle organization (GO:0060236)2.43851984
144embryonic retina morphogenesis in camera-type eye (GO:0060059)2.42867253
145G1 DNA damage checkpoint (GO:0044783)2.42506747
146protein localization to chromosome (GO:0034502)2.42371578
147protein dealkylation (GO:0008214)2.42212586
148regulation of DNA-templated transcription, initiation (GO:2000142)2.39598286
149mRNA transport (GO:0051028)2.38290797
150positive regulation of histone methylation (GO:0031062)2.35380832
151regulation of mRNA catabolic process (GO:0061013)2.35140895
152positive regulation of mRNA catabolic process (GO:0061014)2.35122935
153regulation of mRNA 3-end processing (GO:0031440)2.34846446

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.54877361
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.94777586
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.93275016
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.87928840
5MYC_22102868_ChIP-Seq_BL_Human3.81472220
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.93264120
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.83802208
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.63419815
9KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.62978525
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.54529983
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.51107806
12TCF7_22412390_ChIP-Seq_EML_Mouse2.47232352
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.30705722
14KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.20906214
15KDM2B_26808549_Chip-Seq_DND41_Human2.04231339
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.00507803
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.00445868
18VDR_21846776_ChIP-Seq_THP-1_Human1.95120293
19CIITA_25753668_ChIP-Seq_RAJI_Human1.94137493
20E2F1_21310950_ChIP-Seq_MCF-7_Human1.90479243
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82265691
22SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81113694
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73475173
24DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.72619885
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.70876489
26SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.70852940
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.70630825
28POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70600062
29FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.70233483
30UTX_26944678_Chip-Seq_JUKART_Human1.68107334
31TP63_19390658_ChIP-ChIP_HaCaT_Human1.67341703
32ZNF217_24962896_ChIP-Seq_MCF-7_Human1.66882597
33PKCTHETA_26484144_Chip-Seq_BREAST_Human1.66751344
34STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.66184169
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.65286449
36WT1_19549856_ChIP-ChIP_CCG9911_Human1.65034707
37MAF_26560356_Chip-Seq_TH1_Human1.64549903
38HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.64476054
39CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.63363121
40MYB_26560356_Chip-Seq_TH1_Human1.58287585
41AR_21909140_ChIP-Seq_LNCAP_Human1.55434234
42TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.55016497
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.54152005
44KDM2B_26808549_Chip-Seq_JURKAT_Human1.51858118
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.51070126
46ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.50513089
47RUNX_20019798_ChIP-Seq_JUKART_Human1.46620462
48MYB_26560356_Chip-Seq_TH2_Human1.46358689
49ZFP281_27345836_Chip-Seq_ESCs_Mouse1.44872266
50STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.43659310
51FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.42897859
52ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.39861558
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.38262842
54CTNNB1_20460455_ChIP-Seq_HCT116_Human1.37013981
55SCL_19346495_ChIP-Seq_HPC-7_Human1.35117511
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.33344116
57MYC_19079543_ChIP-ChIP_MESCs_Mouse1.32425996
58P300_27058665_Chip-Seq_ZR-75-30cells_Human1.30676088
59NCOR1_26117541_ChIP-Seq_K562_Human1.30476426
60KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.30129750
61KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.30129750
62KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.30129750
63ELK3_25401928_ChIP-Seq_HUVEC_Human1.29924541
64EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28859027
65SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.27661111
66FUS_26573619_Chip-Seq_HEK293_Human1.27254251
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26804644
68CHD1_26751641_Chip-Seq_LNCaP_Human1.26277786
69WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25983493
70ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23815773
71SALL4_18804426_ChIP-ChIP_XEN_Mouse1.20464483
72NANOG_21062744_ChIP-ChIP_HESCs_Human1.20358863
73PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.17497838
74DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17263669
75CLOCK_20551151_ChIP-Seq_293T_Human1.16214123
76TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.15738891
77FOXM1_26456572_ChIP-Seq_MCF-7_Human1.15269955
78FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.15217312
79E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15079367
80MYC_18555785_ChIP-Seq_MESCs_Mouse1.14337840
81TP53_16413492_ChIP-PET_HCT116_Human1.14102554
82KDM5A_27292631_Chip-Seq_BREAST_Human1.13076110
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.13016154
84STAT3_23295773_ChIP-Seq_U87_Human1.12731775
85CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.10632413
86PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10143139
87CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09346819
88CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08794605
89HIF1A_21447827_ChIP-Seq_MCF-7_Human1.07347369
90MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07080031
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.07067608
92VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.06992224
93FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.06321948
94KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06144193
95NFIB_24661679_ChIP-Seq_LUNG_Mouse1.05549700
96* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05388543
97BRD4_27068464_Chip-Seq_AML-cells_Mouse1.05154768
98EP300_21415370_ChIP-Seq_HL-1_Mouse1.04880964
99RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.04545471
100AHR_22903824_ChIP-Seq_MCF-7_Human1.04135841
101POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04070592
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04070592
103GATA1_22025678_ChIP-Seq_K562_Human1.03842846
104NOTCH1_21737748_ChIP-Seq_TLL_Human1.03566055
105ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03338542
106FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.02990333
107YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02766433
108SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.02317257
109KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01921376
110EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.01100045
111EWS_26573619_Chip-Seq_HEK293_Human1.00995804
112FOXO3_23340844_ChIP-Seq_DLD1_Human1.00857437
113FOXA2_19822575_ChIP-Seq_HepG2_Human1.00518814
114KDM2B_26808549_Chip-Seq_K562_Human1.00493453
115VDR_24763502_ChIP-Seq_THP-1_Human0.99916874
116SMAD4_21799915_ChIP-Seq_A2780_Human0.99723046
117MYCN_18555785_ChIP-Seq_MESCs_Mouse0.99551257
118NELFA_20434984_ChIP-Seq_ESCs_Mouse0.99303082
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.99250389
120TCF4_18268006_ChIP-ChIP_LS174T_Human0.99218564
121IGF1R_20145208_ChIP-Seq_DFB_Human0.99164427
122ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.98771166
123TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98620573
124NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.97935603
125ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97620993
126ESR1_20079471_ChIP-ChIP_T-47D_Human0.97595909
127GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97042341
128SPI1_23127762_ChIP-Seq_K562_Human0.96841593
129ARNT_22903824_ChIP-Seq_MCF-7_Human0.96162202
130PADI4_21655091_ChIP-ChIP_MCF-7_Human0.95713502
131TFEB_21752829_ChIP-Seq_HELA_Human0.95572333
132TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95344313
133ATF3_27146783_Chip-Seq_COLON_Human0.95153418
134MYB_21317192_ChIP-Seq_ERMYB_Mouse0.94929244
135RUNX1_22412390_ChIP-Seq_EML_Mouse0.94029652
136OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92430758
137YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92414475
138NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.92056135
139ISL1_27105846_Chip-Seq_CPCs_Mouse0.91833108
140RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.91395427
141SOX9_24532713_ChIP-Seq_HFSC_Mouse0.91106170
142DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90757676
143GBX2_23144817_ChIP-Seq_PC3_Human0.90697565
144EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90300071
145AR_21572438_ChIP-Seq_LNCaP_Human0.89678712
146CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.89342835
147TCF4_23295773_ChIP-Seq_U87_Human0.89257388
148SMAD_19615063_ChIP-ChIP_OVARY_Human0.89026985
149SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.88209338
150PIAS1_25552417_ChIP-Seq_VCAP_Human0.88043301
151PU_27001747_Chip-Seq_BMDM_Mouse0.87328536
152SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.87119570
153BRD4_25478319_ChIP-Seq_HGPS_Human0.86743374
154* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.86053938
155ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85202608

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.44485800
2MP0008057_abnormal_DNA_replication3.05977265
3MP0005076_abnormal_cell_differentiation2.93717105
4MP0000569_abnormal_digit_pigmentation2.76576793
5MP0010094_abnormal_chromosome_stability2.66775595
6MP0003705_abnormal_hypodermis_morpholog2.63595069
7MP0003123_paternal_imprinting2.62166829
8MP0003111_abnormal_nucleus_morphology2.44860189
9MP0002396_abnormal_hematopoietic_system2.42835212
10MP0003077_abnormal_cell_cycle2.35494370
11MP0010307_abnormal_tumor_latency2.22362684
12MP0002877_abnormal_melanocyte_morpholog2.19730294
13MP0009278_abnormal_bone_marrow2.14631178
14MP0004808_abnormal_hematopoietic_stem2.08403439
15MP0003300_gastrointestinal_ulcer2.05486095
16MP0008961_abnormal_basal_metabolism2.05152198
17MP0004957_abnormal_blastocyst_morpholog1.93619015
18MP0001730_embryonic_growth_arrest1.86879704
19MP0003121_genomic_imprinting1.86581166
20MP0000350_abnormal_cell_proliferation1.86063524
21MP0003763_abnormal_thymus_physiology1.85104897
22MP0000537_abnormal_urethra_morphology1.78303041
23MP0004197_abnormal_fetal_growth/weight/1.77163917
24MP0003984_embryonic_growth_retardation1.75650425
25MP0002088_abnormal_embryonic_growth/wei1.74121628
26MP0001672_abnormal_embryogenesis/_devel1.72804986
27MP0005380_embryogenesis_phenotype1.72804986
28MP0003693_abnormal_embryo_hatching1.71433264
29MP0002084_abnormal_developmental_patter1.70932326
30MP0002086_abnormal_extraembryonic_tissu1.65206289
31MP0000703_abnormal_thymus_morphology1.62921905
32MP0010234_abnormal_vibrissa_follicle1.62865653
33MP0008877_abnormal_DNA_methylation1.61628286
34MP0003566_abnormal_cell_adhesion1.58809783
35MP0000733_abnormal_muscle_development1.56871157
36MP0003890_abnormal_embryonic-extraembry1.56791926
37MP0005409_darkened_coat_color1.52724430
38MP0003221_abnormal_cardiomyocyte_apopto1.48064873
39MP0008007_abnormal_cellular_replicative1.45694364
40MP0002085_abnormal_embryonic_tissue1.45161247
41MP0001697_abnormal_embryo_size1.44447635
42MP0003045_fibrosis1.35674023
43MP0002166_altered_tumor_susceptibility1.33837718
44MP0008995_early_reproductive_senescence1.31335700
45MP0008058_abnormal_DNA_repair1.29857658
46MP0002080_prenatal_lethality1.29126513
47MP0003091_abnormal_cell_migration1.28154936
48MP0002398_abnormal_bone_marrow1.28020534
49MP0001545_abnormal_hematopoietic_system1.26442822
50MP0005397_hematopoietic_system_phenotyp1.26442822
51MP0000428_abnormal_craniofacial_morphol1.25685727
52MP0002925_abnormal_cardiovascular_devel1.24993780
53MP0003656_abnormal_erythrocyte_physiolo1.23165783
54MP0002009_preneoplasia1.20720855
55MP0004185_abnormal_adipocyte_glucose1.19725521
56MP0001915_intracranial_hemorrhage1.18925870
57MP0003787_abnormal_imprinting1.18529183
58MP0003567_abnormal_fetal_cardiomyocyte1.17427804
59MP0004084_abnormal_cardiac_muscle1.15054947
60MP0000383_abnormal_hair_follicle1.13953800
61MP0002019_abnormal_tumor_incidence1.13564440
62MP0004264_abnormal_extraembryonic_tissu1.13179167
63MP0001849_ear_inflammation1.12225943
64MP0002254_reproductive_system_inflammat1.11385454
65MP0009703_decreased_birth_body1.06646371
66MP0002722_abnormal_immune_system1.01857413
67MP0001661_extended_life_span1.01483441
68MP0003941_abnormal_skin_development1.01462968
69MP0003115_abnormal_respiratory_system0.98705576
70MP0003937_abnormal_limbs/digits/tail_de0.98213726
71MP0005023_abnormal_wound_healing0.97194444
72MP0002405_respiratory_system_inflammati0.96880975
73MP0004036_abnormal_muscle_relaxation0.96491243
74MP0003935_abnormal_craniofacial_develop0.96490747
75MP0001293_anophthalmia0.95325525
76MP0002006_tumorigenesis0.94329229
77MP0008770_decreased_survivor_rate0.94116403
78MP0003122_maternal_imprinting0.93670921
79MP0005623_abnormal_meninges_morphology0.93441395
80MP0000689_abnormal_spleen_morphology0.92128526
81MP0000490_abnormal_crypts_of0.92100650
82MP0000313_abnormal_cell_death0.91817355
83MP0001873_stomach_inflammation0.91644363
84MP0005621_abnormal_cell_physiology0.91554867
85MP0004233_abnormal_muscle_weight0.91238196
86MP0006054_spinal_hemorrhage0.90626496
87MP0009115_abnormal_fat_cell0.90511630
88MP0010630_abnormal_cardiac_muscle0.90303688
89MP0000685_abnormal_immune_system0.89945476
90MP0001800_abnormal_humoral_immune0.89324804
91MP0002092_abnormal_eye_morphology0.86637766
92MP0000266_abnormal_heart_morphology0.86453632
93MP0009672_abnormal_birth_weight0.86225215
94MP0005666_abnormal_adipose_tissue0.86102593
95MP0003119_abnormal_digestive_system0.85584582
96MP0001286_abnormal_eye_development0.85561841
97MP0009053_abnormal_anal_canal0.84755369
98MP0001784_abnormal_fluid_regulation0.83889624
99MP0002127_abnormal_cardiovascular_syste0.83100621
100MP0002108_abnormal_muscle_morphology0.82564050
101MP0010030_abnormal_orbit_morphology0.81107284
102MP0005451_abnormal_body_composition0.80863403
103MP0000003_abnormal_adipose_tissue0.79753808
104MP0005375_adipose_tissue_phenotype0.78957115
105MP0005187_abnormal_penis_morphology0.78811033
106MP0000716_abnormal_immune_system0.78636789
107MP0002697_abnormal_eye_size0.77039573
108MP0004087_abnormal_muscle_fiber0.76730388
109MP0004134_abnormal_chest_morphology0.76583252
110MP0000432_abnormal_head_morphology0.76249179
111MP0005220_abnormal_exocrine_pancreas0.73632935
112MP0005384_cellular_phenotype0.73481903
113MP0005248_abnormal_Harderian_gland0.73148789
114MP0002429_abnormal_blood_cell0.72931180
115MP0000371_diluted_coat_color0.72868970
116MP0003303_peritoneal_inflammation0.72801821
117MP0010678_abnormal_skin_adnexa0.71334650
118MP0004130_abnormal_muscle_cell0.69555593
119MP0003943_abnormal_hepatobiliary_system0.69489758
120MP0004947_skin_inflammation0.69454234
121MP0003385_abnormal_body_wall0.68966889
122MP0005310_abnormal_salivary_gland0.68020262
123MP0003828_pulmonary_edema0.67787094
124MP0003453_abnormal_keratinocyte_physiol0.65027900
125MP0002114_abnormal_axial_skeleton0.64995851
126MP0009697_abnormal_copulation0.64215190
127MP0001929_abnormal_gametogenesis0.63901056

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.60291893
2Abnormality of the fingertips (HP:0001211)3.47056907
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.21702517
4Short 4th metacarpal (HP:0010044)3.21702517
5Ependymoma (HP:0002888)3.13506648
6Macroorchidism (HP:0000053)2.96228151
7Abnormality of the astrocytes (HP:0100707)2.82993173
8Astrocytoma (HP:0009592)2.82993173
9Nephroblastoma (Wilms tumor) (HP:0002667)2.78942552
10Embryonal renal neoplasm (HP:0011794)2.73900581
11Colon cancer (HP:0003003)2.73425107
12Prominent nose (HP:0000448)2.71804254
13Subacute progressive viral hepatitis (HP:0006572)2.67884702
14T lymphocytopenia (HP:0005403)2.63336366
15Medulloblastoma (HP:0002885)2.62330002
16Hyperacusis (HP:0010780)2.60543966
17Neoplasm of the oral cavity (HP:0100649)2.56297147
18Increased nuchal translucency (HP:0010880)2.51877857
19Cerebral aneurysm (HP:0004944)2.50420451
20Heterotopia (HP:0002282)2.45120556
21Deviation of the thumb (HP:0009603)2.43218012
22Thyroid carcinoma (HP:0002890)2.43195367
23Long eyelashes (HP:0000527)2.42239433
24Abnormality of the 4th metacarpal (HP:0010012)2.40158312
25Proximal placement of thumb (HP:0009623)2.39357796
26Glioma (HP:0009733)2.38512082
27Truncal obesity (HP:0001956)2.35660214
28Abnormality of T cell number (HP:0011839)2.33670571
29Cystic hygroma (HP:0000476)2.31993392
30High pitched voice (HP:0001620)2.27280106
31Vertebral arch anomaly (HP:0008438)2.25438411
32Obsessive-compulsive behavior (HP:0000722)2.24888461
33Malignant gastrointestinal tract tumors (HP:0006749)2.24010785
34Gastrointestinal carcinoma (HP:0002672)2.24010785
35Selective tooth agenesis (HP:0001592)2.22852584
36Trigonocephaly (HP:0000243)2.22110375
37Subaortic stenosis (HP:0001682)2.21568355
38Abnormality of the left ventricular outflow tract (HP:0011103)2.21568355
39Bladder carcinoma (HP:0002862)2.20403050
40Bladder neoplasm (HP:0009725)2.20403050
41Abnormal hair whorl (HP:0010721)2.20344563
42Neoplasm of striated muscle (HP:0009728)2.19454412
43Broad palm (HP:0001169)2.18201441
44Broad thumb (HP:0011304)2.15956530
45Abnormality of chromosome segregation (HP:0002916)2.15285932
46Spinal cord lesions (HP:0100561)2.13891380
47Syringomyelia (HP:0003396)2.13891380
48Submucous cleft hard palate (HP:0000176)2.13400532
49Acute lymphatic leukemia (HP:0006721)2.13264437
50Curly hair (HP:0002212)2.11546223
51Shallow orbits (HP:0000586)2.08294258
52Basal cell carcinoma (HP:0002671)2.08275568
53Dysmetric saccades (HP:0000641)2.05937376
54Rhabdomyosarcoma (HP:0002859)2.04033969
55Neonatal hypoglycemia (HP:0001998)2.03474167
56Abnormal number of incisors (HP:0011064)2.02314531
57Aortic aneurysm (HP:0004942)2.02194479
58Renal duplication (HP:0000075)2.02057083
59Midline defect of the nose (HP:0004122)2.02047295
60Hepatoblastoma (HP:0002884)2.01524497
61Increased density of long bones (HP:0006392)2.01125171
62Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.01091572
63Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.00711994
64Overgrowth (HP:0001548)1.98077590
65Chromsome breakage (HP:0040012)1.97087397
66Skull defect (HP:0001362)1.95437214
67Low anterior hairline (HP:0000294)1.93452144
68Narrow palate (HP:0000189)1.92584275
69Mitral valve prolapse (HP:0001634)1.92172814
70Ulnar bowing (HP:0003031)1.91729796
71Abnormality of the ischium (HP:0003174)1.90853144
72Overlapping toe (HP:0001845)1.90528492
73Skin tags (HP:0010609)1.90301424
74Bowel diverticulosis (HP:0005222)1.88969675
75Cubitus valgus (HP:0002967)1.86297195
76Relative macrocephaly (HP:0004482)1.86068758
77Urethral obstruction (HP:0000796)1.86003314
78Hematochezia (HP:0002573)1.85433837
79Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.85236050
80Asymmetry of the thorax (HP:0001555)1.85221179
81Capillary hemangiomas (HP:0005306)1.83725017
82Elfin facies (HP:0004428)1.83453481
83Flat acetabular roof (HP:0003180)1.83413303
84Difficulty running (HP:0009046)1.83106885
85Cutis marmorata (HP:0000965)1.82915723
86Chromosomal breakage induced by crosslinking agents (HP:0003221)1.82521472
87Pseudobulbar signs (HP:0002200)1.82305720
88Cafe-au-lait spot (HP:0000957)1.81967298
89Sandal gap (HP:0001852)1.81414479
90Broad phalanges of the hand (HP:0009768)1.81292596
91Pointed chin (HP:0000307)1.80628776
92Neoplasm of the heart (HP:0100544)1.79793668
93Viral hepatitis (HP:0006562)1.79415800
94Smooth philtrum (HP:0000319)1.78607591
95Abnormality of chromosome stability (HP:0003220)1.77251790
96Germ cell neoplasia (HP:0100728)1.76459172
97Renovascular hypertension (HP:0100817)1.76165819
98Genu recurvatum (HP:0002816)1.75674226
99Aplasia/Hypoplasia of the sternum (HP:0006714)1.74127331
100Septate vagina (HP:0001153)1.74009414
101Termporal pattern (HP:0011008)1.73586422
102Insidious onset (HP:0003587)1.73586422
103Papillary thyroid carcinoma (HP:0002895)1.73241194
104Dislocated radial head (HP:0003083)1.72847588
105Biliary tract neoplasm (HP:0100574)1.72684402
106Abnormality of the phalanges of the hallux (HP:0010057)1.71389764
107Abnormality of the columella (HP:0009929)1.71330870
108Embryonal neoplasm (HP:0002898)1.71237460
109Abnormality of oral frenula (HP:0000190)1.71226636
110Absent frontal sinuses (HP:0002688)1.70385836
111Abnormality of the lower motor neuron (HP:0002366)1.70210080
112Fibrous tissue neoplasm (HP:0012316)1.69750982
113Persistence of primary teeth (HP:0006335)1.69629397
114High anterior hairline (HP:0009890)1.69430917
115Transitional cell carcinoma of the bladder (HP:0006740)1.69141727
116Dilatation of the ascending aorta (HP:0005111)1.68878107
117Diastasis recti (HP:0001540)1.67742065
118Ectopic kidney (HP:0000086)1.67664389
119Hypoplastic ischia (HP:0003175)1.66617775
120Broad finger (HP:0001500)1.66541817
121Uterine leiomyosarcoma (HP:0002891)1.65932465
122Leiomyosarcoma (HP:0100243)1.65932465
123Deep philtrum (HP:0002002)1.65635764
124Supernumerary ribs (HP:0005815)1.63927240
125Lip pit (HP:0100267)1.63696194
126Cortical dysplasia (HP:0002539)1.63406701
127Overriding aorta (HP:0002623)1.63335197
128Abnormality of the labia majora (HP:0012881)1.62338475
129Fibroma (HP:0010614)1.60952606
130Abnormality of the nasal septum (HP:0000419)1.60497739
131Missing ribs (HP:0000921)1.59989642
132Abnormal foot bone ossification (HP:0010675)1.59919821
133Thyroiditis (HP:0100646)1.59409673
134Pelvic girdle muscle weakness (HP:0003749)1.59198577
135Hypoplasia of the maxilla (HP:0000327)1.59092038
136Increased number of teeth (HP:0011069)1.58698079
137Hypoplastic iliac wings (HP:0002866)1.58472612
138Thickened calvaria (HP:0002684)1.57815832
139Broad phalanx (HP:0006009)1.57731945
140Ankyloglossia (HP:0010296)1.57702829
141Anal stenosis (HP:0002025)1.57306003
142Acute myeloid leukemia (HP:0004808)1.57219757
143Abnormality of the radial head (HP:0003995)1.56782803
144Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.55233403
145Hypoplastic labia majora (HP:0000059)1.54595305
146Abnormality of the distal phalanx of the thumb (HP:0009617)1.54095744
147Limited elbow extension (HP:0001377)1.53416434
148Aneurysm (HP:0002617)1.53177349
149Recurrent viral infections (HP:0004429)1.52684680
150Thick eyebrow (HP:0000574)1.52530798
151Tapered finger (HP:0001182)1.51960596

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.08274530
2EEF2K3.25903641
3MAP3K103.07912964
4PKN22.59473607
5AKT32.51650342
6TRIB32.40750805
7CDC72.39892420
8STK102.31130604
9RIPK12.28032385
10STK32.26609839
11NEK21.90321180
12BRD41.84018094
13MAP4K11.78928487
14CAMK1D1.71612752
15PTK61.71446533
16ALK1.69879251
17PRPF4B1.57613669
18MTOR1.57513349
19CAMK1G1.57081688
20PNCK1.53782859
21SGK21.47575904
22CDK61.43059968
23PDGFRA1.43057323
24SCYL21.42382864
25LATS11.42311784
26TTN1.35806447
27RPS6KB21.35270205
28FGFR31.31295206
29TTK1.29292523
30CDK41.28723172
31LRRK21.23634723
32MAP3K141.22708572
33ITK1.19675012
34YES11.19010251
35GRK61.11937539
36EIF2AK31.11800841
37STK38L1.11645472
38CDK91.08202600
39CHEK11.06117183
40DMPK1.05303219
41ATR1.05042720
42NEK91.04999345
43SMG11.03539320
44MELK1.01890299
45TRPM71.01576907
46MAP3K71.00239013
47STK240.99954413
48TYRO30.98743609
49STK40.98396284
50MAP3K80.98212465
51PASK0.97890344
52SIK20.97527457
53FGFR10.95409280
54MAP3K60.94048354
55TNIK0.92429465
56CDK70.89898205
57TAF10.89867258
58PDGFRB0.89277324
59ATM0.88914277
60FLT30.88163418
61SIK10.87515436
62TGFBR10.85875211
63WNK10.84242632
64OBSCN0.82170170
65CSK0.81983806
66FGFR40.81253731
67HIPK20.80220455
68WEE10.80185576
69ERN10.80076318
70PIM10.79744034
71CDK20.79547299
72RPS6KA40.79338961
73ICK0.79334633
74JAK10.79101638
75FGFR20.78758396
76BMX0.78591465
77MAP3K130.78009792
78TSSK60.77171763
79JAK30.76989461
80RPS6KB10.75036345
81KSR10.68440857
82NEK60.68149959
83ACVR1B0.67735942
84KSR20.67192214
85MAP3K40.65642471
86RET0.65603991
87PIK3CG0.64427202
88MAP3K90.63927062
89SGK4940.63747397
90SGK2230.63747397
91PLK10.61390457
92CHUK0.61226862
93CDK30.61050385
94AURKB0.60487622
95NEK10.59903003
96TEC0.59874423
97PAK20.59491196
98DDR20.59247223
99PRKAA10.57603602
100LATS20.57582088
101SGK10.57466431
102TGFBR20.57238990
103STK380.56869859
104EPHA30.56785907
105CAMK40.56238660
106MAPK140.56233686
107SGK30.55648504
108IRAK20.55587081
109IRAK10.55575966
110BRSK20.55459527
111TAOK30.54696879
112PRKDC0.54175117
113NLK0.53768103
114MKNK20.53739275
115CSF1R0.53086537
116PTK20.52827918
117CDK10.52637080
118HCK0.51930156
119CHEK20.51831732
120BTK0.51794795
121MKNK10.50400324
122MAPK10.49998053
123PRKAA20.49858578
124TYK20.49547555
125CSNK1D0.48923634
126EIF2AK20.48483656
127PAK40.48035184
128ZAP700.46943260
129MARK30.46628241
130BLK0.46495597
131SRPK10.45660425
132DYRK1B0.45370986
133CDC42BPA0.45188159
134CLK10.42977031
135MAP3K20.42972087
136MAPK100.42673921
137GSK3B0.42402296
138IKBKE0.41934988
139PLK40.41847770
140MARK20.41844246
141CSNK1E0.41318128

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041101.86910560
2Chronic myeloid leukemia_Homo sapiens_hsa052201.83433162
3mRNA surveillance pathway_Homo sapiens_hsa030151.75299162
4mTOR signaling pathway_Homo sapiens_hsa041501.64630058
5Colorectal cancer_Homo sapiens_hsa052101.62976936
6MicroRNAs in cancer_Homo sapiens_hsa052061.60646290
7Primary immunodeficiency_Homo sapiens_hsa053401.58506197
8Small cell lung cancer_Homo sapiens_hsa052221.47641320
9RNA transport_Homo sapiens_hsa030131.46685339
10Lysine degradation_Homo sapiens_hsa003101.46411605
11Dorso-ventral axis formation_Homo sapiens_hsa043201.45072034
12B cell receptor signaling pathway_Homo sapiens_hsa046621.44748955
13Adherens junction_Homo sapiens_hsa045201.42878510
14Circadian rhythm_Homo sapiens_hsa047101.37931212
15Non-homologous end-joining_Homo sapiens_hsa034501.35928663
16Endometrial cancer_Homo sapiens_hsa052131.34666177
17T cell receptor signaling pathway_Homo sapiens_hsa046601.34453259
18DNA replication_Homo sapiens_hsa030301.30708253
19Pancreatic cancer_Homo sapiens_hsa052121.30102103
20Thyroid hormone signaling pathway_Homo sapiens_hsa049191.30094649
21HTLV-I infection_Homo sapiens_hsa051661.29851370
22Viral carcinogenesis_Homo sapiens_hsa052031.27324067
23Spliceosome_Homo sapiens_hsa030401.27022809
24Mismatch repair_Homo sapiens_hsa034301.26489230
25Antigen processing and presentation_Homo sapiens_hsa046121.25289671
26Hippo signaling pathway_Homo sapiens_hsa043901.24635260
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.24260896
28Non-small cell lung cancer_Homo sapiens_hsa052231.23397169
29Fanconi anemia pathway_Homo sapiens_hsa034601.23381482
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.22479737
31Acute myeloid leukemia_Homo sapiens_hsa052211.20929770
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.20572266
33Proteoglycans in cancer_Homo sapiens_hsa052051.19522092
34Transcriptional misregulation in cancer_Homo sapiens_hsa052021.19382614
35Basal cell carcinoma_Homo sapiens_hsa052171.15489014
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14887545
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.10240459
38Hepatitis B_Homo sapiens_hsa051611.10029646
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.09364284
40Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.08488786
41Viral myocarditis_Homo sapiens_hsa054161.08399702
42Notch signaling pathway_Homo sapiens_hsa043301.07838010
43One carbon pool by folate_Homo sapiens_hsa006701.06748730
44Neurotrophin signaling pathway_Homo sapiens_hsa047221.04372121
45Glioma_Homo sapiens_hsa052141.01759308
46Oocyte meiosis_Homo sapiens_hsa041141.01751731
47Focal adhesion_Homo sapiens_hsa045101.01143251
48Type II diabetes mellitus_Homo sapiens_hsa049301.00791988
49p53 signaling pathway_Homo sapiens_hsa041151.00411534
50Prostate cancer_Homo sapiens_hsa052150.99644389
51NF-kappa B signaling pathway_Homo sapiens_hsa040640.99303769
52AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.97781728
53TGF-beta signaling pathway_Homo sapiens_hsa043500.96128382
54Central carbon metabolism in cancer_Homo sapiens_hsa052300.95066435
55Osteoclast differentiation_Homo sapiens_hsa043800.93913386
56Herpes simplex infection_Homo sapiens_hsa051680.93615418
57Insulin resistance_Homo sapiens_hsa049310.93557708
58FoxO signaling pathway_Homo sapiens_hsa040680.92129648
59Base excision repair_Homo sapiens_hsa034100.91290158
60Renal cell carcinoma_Homo sapiens_hsa052110.91178329
61Toxoplasmosis_Homo sapiens_hsa051450.91006507
62VEGF signaling pathway_Homo sapiens_hsa043700.90576606
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.89880922
64Thyroid cancer_Homo sapiens_hsa052160.89780131
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.89310978
66Pathways in cancer_Homo sapiens_hsa052000.87324799
67Wnt signaling pathway_Homo sapiens_hsa043100.86916730
68Prolactin signaling pathway_Homo sapiens_hsa049170.85893829
69Estrogen signaling pathway_Homo sapiens_hsa049150.85851032
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.84125212
71Melanoma_Homo sapiens_hsa052180.83630886
72RNA degradation_Homo sapiens_hsa030180.82909473
73Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82685028
74Systemic lupus erythematosus_Homo sapiens_hsa053220.82571243
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82365916
76Hepatitis C_Homo sapiens_hsa051600.81146682
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.80671724
78MAPK signaling pathway_Homo sapiens_hsa040100.79228087
79Influenza A_Homo sapiens_hsa051640.79174052
80Platelet activation_Homo sapiens_hsa046110.79107178
81Apoptosis_Homo sapiens_hsa042100.77984778
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.76948383
83Choline metabolism in cancer_Homo sapiens_hsa052310.75359385
84Measles_Homo sapiens_hsa051620.75032841
85TNF signaling pathway_Homo sapiens_hsa046680.72770505
86NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72432890
87Regulation of actin cytoskeleton_Homo sapiens_hsa048100.72410004
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.71584592
89Long-term potentiation_Homo sapiens_hsa047200.71029004
90ErbB signaling pathway_Homo sapiens_hsa040120.70596830
91Alcoholism_Homo sapiens_hsa050340.70515560
92Basal transcription factors_Homo sapiens_hsa030220.70361622
93Insulin signaling pathway_Homo sapiens_hsa049100.70130852
94Epstein-Barr virus infection_Homo sapiens_hsa051690.69994539
95Inositol phosphate metabolism_Homo sapiens_hsa005620.69063393
96HIF-1 signaling pathway_Homo sapiens_hsa040660.69020998
97AMPK signaling pathway_Homo sapiens_hsa041520.68799632
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68569807
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68364566
100Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.65607101
101Rap1 signaling pathway_Homo sapiens_hsa040150.65535945
102ECM-receptor interaction_Homo sapiens_hsa045120.65022202
103Chemokine signaling pathway_Homo sapiens_hsa040620.64808523
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.63164327
105Long-term depression_Homo sapiens_hsa047300.62460979
106cGMP-PKG signaling pathway_Homo sapiens_hsa040220.62340218
107Glucagon signaling pathway_Homo sapiens_hsa049220.61841318
108Bladder cancer_Homo sapiens_hsa052190.61602242
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.60811178
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60576530
111Hedgehog signaling pathway_Homo sapiens_hsa043400.59776261
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.58987397
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58814229
114GnRH signaling pathway_Homo sapiens_hsa049120.58494565
115Homologous recombination_Homo sapiens_hsa034400.58197880
116Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58154243
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.56837132
118Tight junction_Homo sapiens_hsa045300.55649028

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