SCAMP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.54862824
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.06029221
3synaptic vesicle exocytosis (GO:0016079)5.02351218
4synaptic vesicle maturation (GO:0016188)4.99867343
5vocalization behavior (GO:0071625)4.92378525
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.90527852
7locomotory exploration behavior (GO:0035641)4.77393641
8regulation of synaptic vesicle exocytosis (GO:2000300)4.70079587
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.64500084
10glutamate secretion (GO:0014047)4.62011084
11neuron cell-cell adhesion (GO:0007158)4.51613288
12protein localization to synapse (GO:0035418)4.40588119
13regulation of glutamate receptor signaling pathway (GO:1900449)4.35528306
14synaptic vesicle docking involved in exocytosis (GO:0016081)4.35273259
15regulation of synaptic vesicle transport (GO:1902803)4.19757916
16neurotransmitter secretion (GO:0007269)4.19317490
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.16716676
18neuronal action potential propagation (GO:0019227)4.07411919
19neurotransmitter-gated ion channel clustering (GO:0072578)4.01443959
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.97587504
21exploration behavior (GO:0035640)3.93102381
22glutamate receptor signaling pathway (GO:0007215)3.86063703
23pyrimidine nucleobase catabolic process (GO:0006208)3.85680192
24regulation of long-term neuronal synaptic plasticity (GO:0048169)3.80293822
25regulation of neuronal synaptic plasticity (GO:0048168)3.80067405
26neuron-neuron synaptic transmission (GO:0007270)3.78511545
27layer formation in cerebral cortex (GO:0021819)3.77719786
28cellular potassium ion homeostasis (GO:0030007)3.77473185
29synaptic transmission, glutamatergic (GO:0035249)3.76909573
30gamma-aminobutyric acid transport (GO:0015812)3.67944835
31regulation of synapse structural plasticity (GO:0051823)3.67713599
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.67400036
33proline transport (GO:0015824)3.56498435
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.53052198
35neurotransmitter transport (GO:0006836)3.51682741
36gamma-aminobutyric acid signaling pathway (GO:0007214)3.43411337
37positive regulation of membrane potential (GO:0045838)3.43397871
38regulation of excitatory postsynaptic membrane potential (GO:0060079)3.40120482
39long-term memory (GO:0007616)3.39871579
40neuron recognition (GO:0008038)3.38735777
41nucleobase catabolic process (GO:0046113)3.34462894
42negative regulation of synaptic transmission, GABAergic (GO:0032229)3.33896629
43response to histamine (GO:0034776)3.33578420
44dendritic spine morphogenesis (GO:0060997)3.32528692
45regulation of postsynaptic membrane potential (GO:0060078)3.30357207
46long-term synaptic potentiation (GO:0060291)3.29635914
47neuromuscular process controlling posture (GO:0050884)3.29623676
48regulation of synaptic transmission, glutamatergic (GO:0051966)3.26561801
49activation of protein kinase A activity (GO:0034199)3.26489635
50regulation of neurotransmitter levels (GO:0001505)3.23769803
51presynaptic membrane assembly (GO:0097105)3.22958722
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.22363911
53negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.22307833
54positive regulation of synapse maturation (GO:0090129)3.18003560
55positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.17612620
56transmission of nerve impulse (GO:0019226)3.15923401
57regulation of synaptic plasticity (GO:0048167)3.15772908
58positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.15207089
59regulation of vesicle fusion (GO:0031338)3.13279042
60relaxation of smooth muscle (GO:0044557)3.13135524
61regulation of neurotransmitter secretion (GO:0046928)3.11703869
62membrane hyperpolarization (GO:0060081)3.11686416
63synaptic vesicle endocytosis (GO:0048488)3.09475004
64regulation of dendritic spine morphogenesis (GO:0061001)3.09071395
65response to auditory stimulus (GO:0010996)3.08562694
66postsynaptic membrane organization (GO:0001941)3.07865592
67sodium ion export (GO:0071436)3.07793581
68cerebellar Purkinje cell differentiation (GO:0021702)3.06988985
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.05472197
70regulation of autophagic vacuole assembly (GO:2000785)3.03748774
71detection of calcium ion (GO:0005513)3.01891659
72presynaptic membrane organization (GO:0097090)3.01755531
73synapse assembly (GO:0007416)3.01488751
74axonal fasciculation (GO:0007413)3.00534979
75regulation of phosphoprotein phosphatase activity (GO:0043666)2.99012094
76coenzyme catabolic process (GO:0009109)2.98894862
77auditory behavior (GO:0031223)2.96073612
78vesicle transport along microtubule (GO:0047496)2.96068419
79behavioral response to cocaine (GO:0048148)2.95783931
80regulation of neurotransmitter transport (GO:0051588)2.94729541
81cerebellar granule cell differentiation (GO:0021707)2.94253249
82startle response (GO:0001964)2.92878538
83positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.92006473
84glycosphingolipid biosynthetic process (GO:0006688)2.91824479
85neuromuscular process controlling balance (GO:0050885)2.90833859
86mating behavior (GO:0007617)2.90374240
87innervation (GO:0060384)2.90125517
88prepulse inhibition (GO:0060134)2.90073465
89positive regulation of neurotransmitter transport (GO:0051590)2.88738149
90dendrite morphogenesis (GO:0048813)2.88488015
91membrane depolarization (GO:0051899)2.87536566
92membrane depolarization during action potential (GO:0086010)2.87122427
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.86199422
94activation of protein kinase B activity (GO:0032148)2.86067191
95positive regulation of catecholamine secretion (GO:0033605)2.85294204
96positive regulation of synaptic transmission (GO:0050806)2.85080819
97behavioral fear response (GO:0001662)2.83783292
98behavioral defense response (GO:0002209)2.83783292
99synaptic transmission (GO:0007268)2.82921195
100learning (GO:0007612)2.82265066
101regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.80373187
102cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.79578673
103regulation of synaptic transmission (GO:0050804)2.76492815
104synapse organization (GO:0050808)2.75438998
105regulation of glutamate secretion (GO:0014048)2.74294033
106glycine transport (GO:0015816)2.74217469
107negative regulation of cytosolic calcium ion concentration (GO:0051481)2.72966079
108positive regulation of neurotransmitter secretion (GO:0001956)2.72569932
109calcium ion-dependent exocytosis (GO:0017156)2.72324063
110fear response (GO:0042596)2.71792772
111neuromuscular process (GO:0050905)2.70439977
112long term synaptic depression (GO:0060292)2.69760691
113regulation of acyl-CoA biosynthetic process (GO:0050812)2.69328324
114positive regulation of dendritic spine morphogenesis (GO:0061003)2.68597320
115protein localization to cilium (GO:0061512)2.68521258
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.64052408
117regulation of coenzyme metabolic process (GO:0051196)2.60208406
118regulation of cofactor metabolic process (GO:0051193)2.60208406
119regulation of vacuole organization (GO:0044088)2.59608382
120inositol phosphate catabolic process (GO:0071545)2.58751760
121DNA double-strand break processing (GO:0000729)2.57972381
122righting reflex (GO:0060013)2.53042265
123atrial cardiac muscle cell action potential (GO:0086014)2.52603055
124insulin secretion (GO:0030073)2.49854506
125negative regulation of microtubule polymerization (GO:0031115)2.42336854
126acrosome reaction (GO:0007340)2.39709566
127positive regulation of synapse assembly (GO:0051965)2.37436986
128membrane budding (GO:0006900)2.33426828
129positive regulation of glycolytic process (GO:0045821)2.32399155
130neuronal ion channel clustering (GO:0045161)2.31974570
131regulation of synapse assembly (GO:0051963)2.28848015
132organelle transport along microtubule (GO:0072384)2.24055629
133mechanosensory behavior (GO:0007638)2.21348446
134intraciliary transport (GO:0042073)2.20324640
135establishment of mitochondrion localization (GO:0051654)2.19566079
136dendritic spine organization (GO:0097061)2.18974822
137regulation of feeding behavior (GO:0060259)2.17854080
138endoplasmic reticulum organization (GO:0007029)2.17671467
139cell communication involved in cardiac conduction (GO:0086065)2.17540760
140positive regulation of mitochondrial fission (GO:0090141)2.15426543
141cell communication by electrical coupling (GO:0010644)2.14693256
142membrane assembly (GO:0071709)2.14461552
143regulation of dendritic spine development (GO:0060998)2.13374390
144limb bud formation (GO:0060174)2.13274390
145regulation of oxidative stress-induced neuron death (GO:1903203)2.12909085
146regulation of sulfur metabolic process (GO:0042762)2.12744904
147vascular smooth muscle contraction (GO:0014829)2.12607184
148dendrite development (GO:0016358)2.11272451

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.03542841
2EZH2_22144423_ChIP-Seq_EOC_Human4.97367474
3GBX2_23144817_ChIP-Seq_PC3_Human3.53006167
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.92796955
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.87296301
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75480766
7REST_21632747_ChIP-Seq_MESCs_Mouse2.47637611
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.46883301
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.46883301
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.45687466
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.42682321
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.39294520
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.38170783
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36067970
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31777741
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.30144170
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.28470178
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17196033
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.17096386
20* RARB_27405468_Chip-Seq_BRAIN_Mouse2.15498776
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09937888
22TAF15_26573619_Chip-Seq_HEK293_Human2.09177490
23DROSHA_22980978_ChIP-Seq_HELA_Human2.08951067
24* EZH2_27294783_Chip-Seq_ESCs_Mouse2.07336970
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.00921236
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.99011439
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.96040701
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.90884323
29AR_21572438_ChIP-Seq_LNCaP_Human1.89005612
30EWS_26573619_Chip-Seq_HEK293_Human1.84294123
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.80134311
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.77000746
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73834246
34SMAD4_21799915_ChIP-Seq_A2780_Human1.71927654
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.67120138
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.65329316
37CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.64517376
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.62466795
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60612291
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54012545
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.53916664
42* P300_19829295_ChIP-Seq_ESCs_Human1.53804541
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50178796
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.47857188
45PIAS1_25552417_ChIP-Seq_VCAP_Human1.44255796
46ZNF274_21170338_ChIP-Seq_K562_Hela1.44154808
47MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.44045626
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.41449370
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41003811
50* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40092419
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.38600679
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.38074210
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.37056479
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.37039315
55SMAD3_21741376_ChIP-Seq_EPCs_Human1.36107286
56AR_25329375_ChIP-Seq_VCAP_Human1.34757281
57OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34047036
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.33756970
59SOX2_21211035_ChIP-Seq_LN229_Gbm1.33644215
60SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33236914
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33134892
62* CBP_20019798_ChIP-Seq_JUKART_Human1.31434119
63* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31434119
64SMAD_19615063_ChIP-ChIP_OVARY_Human1.30191331
65* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.29039206
66WT1_19549856_ChIP-ChIP_CCG9911_Human1.28866112
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27962779
68HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.27033307
69EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26285443
70IGF1R_20145208_ChIP-Seq_DFB_Human1.26095431
71* STAT3_23295773_ChIP-Seq_U87_Human1.26040066
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.24751294
73BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.24062299
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23518360
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23021058
76RNF2_27304074_Chip-Seq_NSC_Mouse1.22400439
77TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.19501691
78EP300_21415370_ChIP-Seq_HL-1_Mouse1.19392068
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17314500
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17314500
81ESR1_20079471_ChIP-ChIP_T-47D_Human1.17008690
82RING1B_27294783_Chip-Seq_ESCs_Mouse1.16197790
83KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15367574
84FLI1_27457419_Chip-Seq_LIVER_Mouse1.15345569
85* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.14989055
86* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.14989055
87AR_19668381_ChIP-Seq_PC3_Human1.12908344
88ARNT_22903824_ChIP-Seq_MCF-7_Human1.12551563
89* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12439746
90* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11502611
91* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.09386921
92RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08594184
93TCF4_23295773_ChIP-Seq_U87_Human1.08384349
94AHR_22903824_ChIP-Seq_MCF-7_Human1.08065386
95TAL1_26923725_Chip-Seq_HPCs_Mouse1.06812238
96* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06270001
97TCF4_22108803_ChIP-Seq_LS180_Human1.05709988
98PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05697525
99* RUNX2_22187159_ChIP-Seq_PCA_Human1.05294657
100* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05192971
101FUS_26573619_Chip-Seq_HEK293_Human1.04893755
102VDR_22108803_ChIP-Seq_LS180_Human1.04508721
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04149350
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03308678
105NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02145762
106BCAT_22108803_ChIP-Seq_LS180_Human1.02006038
107YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01380240
108ER_23166858_ChIP-Seq_MCF-7_Human1.01083219
109* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01049080
110STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.00092013
111TBL1_22424771_ChIP-Seq_293T_Human0.99745272
112TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98386857
113SMAD3_21741376_ChIP-Seq_ESCs_Human0.98283198
114LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97482697
115PRDM14_20953172_ChIP-Seq_ESCs_Human0.97312140
116CMYC_18555785_Chip-Seq_ESCs_Mouse0.97055051
117CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96573771
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94791157
119RING1B_27294783_Chip-Seq_NPCs_Mouse0.93850962
120* SMAD4_21741376_ChIP-Seq_HESCs_Human0.92661623
121NANOG_18555785_Chip-Seq_ESCs_Mouse0.92569980
122TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91804690
123MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90852350
124DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90563110
125FLI1_21867929_ChIP-Seq_TH2_Mouse0.89489601
126* SMAD3_21741376_ChIP-Seq_HESCs_Human0.88903793
127JUN_21703547_ChIP-Seq_K562_Human0.88329473
128* TP53_18474530_ChIP-ChIP_U2OS_Human0.87738477
129KDM2B_26808549_Chip-Seq_REH_Human0.87670766
130TP53_16413492_ChIP-PET_HCT116_Human0.87341938

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.48675000
2MP0003880_abnormal_central_pattern4.62222782
3MP0003635_abnormal_synaptic_transmissio3.86604906
4MP0004270_analgesia3.49685855
5MP0009745_abnormal_behavioral_response3.19302299
6MP0002063_abnormal_learning/memory/cond3.11814818
7MP0002064_seizures3.03511458
8MP0009046_muscle_twitch3.02748812
9MP0001968_abnormal_touch/_nociception3.02417096
10MP0002822_catalepsy2.78836451
11MP0002572_abnormal_emotion/affect_behav2.70677805
12MP0005423_abnormal_somatic_nervous2.70406722
13MP0002734_abnormal_mechanical_nocicepti2.67729689
14MP0002272_abnormal_nervous_system2.58384883
15MP0001486_abnormal_startle_reflex2.52894831
16MP0002736_abnormal_nociception_after2.44020660
17MP0001501_abnormal_sleep_pattern2.31222203
18MP0002735_abnormal_chemical_nociception2.23772614
19MP0001440_abnormal_grooming_behavior2.16010283
20MP0002733_abnormal_thermal_nociception2.05490105
21MP0006276_abnormal_autonomic_nervous1.99852836
22MP0002102_abnormal_ear_morphology1.99207295
23MP0002067_abnormal_sensory_capabilities1.98088336
24MP0009780_abnormal_chondrocyte_physiolo1.97843414
25MP0001970_abnormal_pain_threshold1.95331224
26MP0005646_abnormal_pituitary_gland1.89069200
27MP0003329_amyloid_beta_deposits1.86439623
28MP0002909_abnormal_adrenal_gland1.86243667
29MP0005248_abnormal_Harderian_gland1.78976742
30MP0002184_abnormal_innervation1.77504291
31MP0005386_behavior/neurological_phenoty1.77202433
32MP0004924_abnormal_behavior1.77202433
33MP0001984_abnormal_olfaction1.73593000
34MP0002557_abnormal_social/conspecific_i1.70163146
35MP0001529_abnormal_vocalization1.68934137
36MP0008569_lethality_at_weaning1.64840257
37MP0000778_abnormal_nervous_system1.64730426
38MP0003315_abnormal_perineum_morphology1.63875250
39MP0010386_abnormal_urinary_bladder1.59538513
40MP0005551_abnormal_eye_electrophysiolog1.57169279
41MP0003879_abnormal_hair_cell1.56798056
42MP0004811_abnormal_neuron_physiology1.52601211
43MP0004885_abnormal_endolymph1.52426633
44MP0004858_abnormal_nervous_system1.51121616
45MP0005645_abnormal_hypothalamus_physiol1.49512303
46MP0001502_abnormal_circadian_rhythm1.47210531
47MP0002160_abnormal_reproductive_system1.46783106
48MP0000955_abnormal_spinal_cord1.44015385
49MP0003121_genomic_imprinting1.42986414
50MP0002882_abnormal_neuron_morphology1.39085388
51MP0002066_abnormal_motor_capabilities/c1.34582147
52MP0003122_maternal_imprinting1.27772313
53MP0003633_abnormal_nervous_system1.27140816
54MP0004142_abnormal_muscle_tone1.27054842
55MP0000013_abnormal_adipose_tissue1.24888700
56MP0001905_abnormal_dopamine_level1.23575642
57MP0003787_abnormal_imprinting1.22019809
58MP0002233_abnormal_nose_morphology1.18086837
59MP0001188_hyperpigmentation1.17087502
60MP0002229_neurodegeneration1.17053431
61MP0008004_abnormal_stomach_pH1.16091920
62MP0009697_abnormal_copulation1.16084351
63MP0008877_abnormal_DNA_methylation1.14065227
64MP0002090_abnormal_vision1.13633798
65MP0003890_abnormal_embryonic-extraembry1.13430639
66MP0002234_abnormal_pharynx_morphology1.12928745
67MP0004084_abnormal_cardiac_muscle1.08635209
68MP0000462_abnormal_digestive_system1.06167780
69MP0004272_abnormal_basement_membrane1.06075184
70MP0003631_nervous_system_phenotype1.06044596
71MP0004742_abnormal_vestibular_system1.04911622
72MP0000537_abnormal_urethra_morphology1.02301688
73MP0003385_abnormal_body_wall1.00642720
74MP0003183_abnormal_peptide_metabolism1.00223865
75MP0002152_abnormal_brain_morphology0.97752446
76MP0005410_abnormal_fertilization0.97706163
77MP0005535_abnormal_body_temperature0.97602268
78MP0003690_abnormal_glial_cell0.96594927
79MP0002751_abnormal_autonomic_nervous0.96222692
80MP0000569_abnormal_digit_pigmentation0.95960394
81MP0002069_abnormal_eating/drinking_beha0.94829602
82MP0003634_abnormal_glial_cell0.91385112
83MP0010234_abnormal_vibrissa_follicle0.90565256
84MP0000604_amyloidosis0.90416900
85MP0004043_abnormal_pH_regulation0.89104121
86MP0002638_abnormal_pupillary_reflex0.88291228
87MP0010678_abnormal_skin_adnexa0.86881199
88MP0008872_abnormal_physiological_respon0.86691005
89MP0006072_abnormal_retinal_apoptosis0.86095976
90MP0001177_atelectasis0.85797530
91MP0001963_abnormal_hearing_physiology0.85216031
92MP0004085_abnormal_heartbeat0.85199943
93MP0000751_myopathy0.84242166
94MP0003119_abnormal_digestive_system0.84057469
95MP0002752_abnormal_somatic_nervous0.83369073
96MP0002837_dystrophic_cardiac_calcinosis0.82161261
97MP0000427_abnormal_hair_cycle0.82004455
98MP0001270_distended_abdomen0.81855378
99MP0005367_renal/urinary_system_phenotyp0.81523611
100MP0000516_abnormal_urinary_system0.81523611
101MP0008789_abnormal_olfactory_epithelium0.81495482
102MP0005391_vision/eye_phenotype0.81351209
103MP0000631_abnormal_neuroendocrine_gland0.80354219
104MP0003937_abnormal_limbs/digits/tail_de0.80212732
105MP0001664_abnormal_digestion0.80005477
106MP0008874_decreased_physiological_sensi0.79613844
107MP0003632_abnormal_nervous_system0.77119923
108MP0000920_abnormal_myelination0.75053536
109MP0003123_paternal_imprinting0.74686054
110MP0003755_abnormal_palate_morphology0.72980253
111MP0004145_abnormal_muscle_electrophysio0.72931486
112MP0002876_abnormal_thyroid_physiology0.72714480
113MP0003935_abnormal_craniofacial_develop0.71802866
114MP0005253_abnormal_eye_physiology0.70271155
115MP0001299_abnormal_eye_distance/0.67446952
116MP0008961_abnormal_basal_metabolism0.65724119
117MP0005499_abnormal_olfactory_system0.64352172
118MP0005394_taste/olfaction_phenotype0.64352172
119MP0003075_altered_response_to0.61929612
120MP0004215_abnormal_myocardial_fiber0.61287543
121MP0001485_abnormal_pinna_reflex0.60445701
122MP0004233_abnormal_muscle_weight0.58786057
123MP0005623_abnormal_meninges_morphology0.57737113
124MP0004484_altered_response_of0.54014670
125MP0001943_abnormal_respiration0.53454433
126MP0003172_abnormal_lysosome_physiology0.53076228
127MP0003283_abnormal_digestive_organ0.52819505
128MP0005167_abnormal_blood-brain_barrier0.52173193
129MP0005187_abnormal_penis_morphology0.51499408
130MP0000026_abnormal_inner_ear0.50708689

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.53928877
2Myokymia (HP:0002411)5.91855137
3Focal seizures (HP:0007359)5.38924977
4Atonic seizures (HP:0010819)4.81602697
5Epileptic encephalopathy (HP:0200134)4.72686029
6Visual hallucinations (HP:0002367)4.69221185
7Absence seizures (HP:0002121)4.39488090
8Febrile seizures (HP:0002373)4.24890134
9Progressive cerebellar ataxia (HP:0002073)4.08443042
10Dialeptic seizures (HP:0011146)4.01508220
11Generalized tonic-clonic seizures (HP:0002069)3.88060056
12Action tremor (HP:0002345)3.51734376
13Supranuclear gaze palsy (HP:0000605)3.36093617
14Hypothermia (HP:0002045)3.31086854
15Hyperventilation (HP:0002883)3.21574998
16Mutism (HP:0002300)3.09049101
17Broad-based gait (HP:0002136)3.08276593
18Dysdiadochokinesis (HP:0002075)3.08246778
19Ankle clonus (HP:0011448)3.07252481
20Abnormal eating behavior (HP:0100738)3.04417004
21Neurofibrillary tangles (HP:0002185)2.99040103
22Gaze-evoked nystagmus (HP:0000640)2.92722311
23Anxiety (HP:0000739)2.88948242
24Depression (HP:0000716)2.88226288
25Dysmetria (HP:0001310)2.84935058
26Impaired vibration sensation in the lower limbs (HP:0002166)2.83786504
27Truncal ataxia (HP:0002078)2.83531481
28Poor eye contact (HP:0000817)2.76857066
29Progressive inability to walk (HP:0002505)2.75971776
30Hyperinsulinemic hypoglycemia (HP:0000825)2.75767651
31Pheochromocytoma (HP:0002666)2.74668037
32Cerebral inclusion bodies (HP:0100314)2.73400787
33Postural instability (HP:0002172)2.69233371
34Urinary bladder sphincter dysfunction (HP:0002839)2.68540333
35Excessive salivation (HP:0003781)2.66918378
36Drooling (HP:0002307)2.66918378
37Hypoglycemic seizures (HP:0002173)2.66462570
38Epileptiform EEG discharges (HP:0011182)2.66240751
39Polyphagia (HP:0002591)2.63052649
40Abnormal social behavior (HP:0012433)2.60280423
41Impaired social interactions (HP:0000735)2.60280423
42Limb dystonia (HP:0002451)2.57601219
43Amblyopia (HP:0000646)2.56556981
44EEG with generalized epileptiform discharges (HP:0011198)2.55837425
45Torticollis (HP:0000473)2.55166209
46Intestinal atresia (HP:0011100)2.54248667
47Neuroendocrine neoplasm (HP:0100634)2.53766294
48Resting tremor (HP:0002322)2.50984308
49Termporal pattern (HP:0011008)2.50000603
50Insidious onset (HP:0003587)2.50000603
51Genetic anticipation (HP:0003743)2.49223325
52Papilledema (HP:0001085)2.46102087
53Scanning speech (HP:0002168)2.45567692
54Spastic gait (HP:0002064)2.42568609
55Exercise-induced muscle cramps (HP:0003710)2.42408583
56Intention tremor (HP:0002080)2.40201840
57Agitation (HP:0000713)2.39312264
58Hypsarrhythmia (HP:0002521)2.35796010
59Hepatoblastoma (HP:0002884)2.35009510
60Hypoglycemic coma (HP:0001325)2.34464798
61Abnormality of binocular vision (HP:0011514)2.33229024
62Diplopia (HP:0000651)2.33229024
63Focal dystonia (HP:0004373)2.32498945
64Hemiparesis (HP:0001269)2.31224188
65Urinary urgency (HP:0000012)2.29948848
66Bradykinesia (HP:0002067)2.26639608
67Sensory axonal neuropathy (HP:0003390)2.24105659
68Abnormality of the corticospinal tract (HP:0002492)2.22619123
69Retinal dysplasia (HP:0007973)2.22473004
70Status epilepticus (HP:0002133)2.20812380
71Inability to walk (HP:0002540)2.18239507
72Generalized myoclonic seizures (HP:0002123)2.17941661
73Absent speech (HP:0001344)2.16563153
74Craniofacial dystonia (HP:0012179)2.15224632
75Gait imbalance (HP:0002141)2.15129858
76Central scotoma (HP:0000603)2.14870111
77Stereotypic behavior (HP:0000733)2.14162597
78Dysmetric saccades (HP:0000641)2.13177800
79Fetal akinesia sequence (HP:0001989)2.11063745
80Papillary thyroid carcinoma (HP:0002895)2.09068161
81Impaired smooth pursuit (HP:0007772)2.07324286
82Neuronal loss in central nervous system (HP:0002529)2.06624523
83Thyroid carcinoma (HP:0002890)2.05567091
84Ventricular fibrillation (HP:0001663)2.05221187
85Blue irides (HP:0000635)2.04496306
86Degeneration of the lateral corticospinal tracts (HP:0002314)2.02370003
87Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.02370003
88Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.01526424
89Lower limb muscle weakness (HP:0007340)2.01481596
90Failure to thrive in infancy (HP:0001531)1.99439064
91Gait ataxia (HP:0002066)1.97309440
92Impaired vibratory sensation (HP:0002495)1.97079509
93Megalencephaly (HP:0001355)1.96748982
94Medial flaring of the eyebrow (HP:0010747)1.95513813
95Akinesia (HP:0002304)1.93084135
96Abnormality of macular pigmentation (HP:0008002)1.90074875
97Hemiplegia (HP:0002301)1.87724327
98Sex reversal (HP:0012245)1.87672080
99Abnormal sex determination (HP:0012244)1.87672080
100Specific learning disability (HP:0001328)1.85798763
101Abnormality of the lower motor neuron (HP:0002366)1.85060509
102Abnormality of ocular smooth pursuit (HP:0000617)1.84577767
103Genital tract atresia (HP:0001827)1.83712958
104Muscular hypotonia of the trunk (HP:0008936)1.83280556
105Abnormality of saccadic eye movements (HP:0000570)1.81808028
106Abnormality of the pancreatic islet cells (HP:0006476)1.80537673
107Abnormality of endocrine pancreas physiology (HP:0012093)1.80537673
108Dynein arm defect of respiratory motile cilia (HP:0012255)1.80286654
109Absent/shortened dynein arms (HP:0200106)1.80286654
110Nephrogenic diabetes insipidus (HP:0009806)1.80131558
111Absent eyebrow (HP:0002223)1.79643359
112Psychosis (HP:0000709)1.79563563
113Rimmed vacuoles (HP:0003805)1.79175985
114Buphthalmos (HP:0000557)1.78882496
115Rigidity (HP:0002063)1.78185811
116Abnormality of salivation (HP:0100755)1.77946582
117Incomplete penetrance (HP:0003829)1.77920160
118Postural tremor (HP:0002174)1.77354573
119Congenital stationary night blindness (HP:0007642)1.76838481
120Congenital primary aphakia (HP:0007707)1.75421276
121Spastic tetraplegia (HP:0002510)1.75015370
122Aqueductal stenosis (HP:0002410)1.75013169
123Type II lissencephaly (HP:0007260)1.75007104
124Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.75003267
125Neoplasm of the peripheral nervous system (HP:0100007)1.74957448
126Clonus (HP:0002169)1.74805130
127Cortical dysplasia (HP:0002539)1.73265174
128Aplasia/hypoplasia of the uterus (HP:0008684)1.72581458
129Hyperthyroidism (HP:0000836)1.72517686
130Abnormality of the intrinsic pathway (HP:0010989)1.72494759
131Vaginal atresia (HP:0000148)1.72192815
132Poor suck (HP:0002033)1.72133988
133Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.72087784
134Syncope (HP:0001279)1.71409004
135Protruding tongue (HP:0010808)1.70508286
136Hypoventilation (HP:0002791)1.70480698
137Abnormal ciliary motility (HP:0012262)1.70441118
138Delayed gross motor development (HP:0002194)1.70277007
139Symptomatic seizures (HP:0011145)1.68174329
140Lissencephaly (HP:0001339)1.67124172
141Postaxial hand polydactyly (HP:0001162)1.65792419
142Male pseudohermaphroditism (HP:0000037)1.65008849
143Occipital encephalocele (HP:0002085)1.64480746
144Gastrointestinal atresia (HP:0002589)1.63813177
145Reduced antithrombin III activity (HP:0001976)1.63514386
146Curly hair (HP:0002212)1.62903602
147True hermaphroditism (HP:0010459)1.61741936
148Morphological abnormality of the pyramidal tract (HP:0002062)1.60649291
149Pachygyria (HP:0001302)1.58881146
150Ketoacidosis (HP:0001993)1.58700145

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.11854728
2MAP3K93.82326799
3EPHA43.76275757
4MARK13.32366405
5MAP3K42.89021087
6CASK2.67411573
7MINK12.54062229
8MAP2K72.49952562
9KSR22.19561647
10DAPK22.16175961
11STK38L2.13775531
12NTRK22.13410076
13MAP3K122.09902429
14TRIM282.07237828
15CSNK1G32.04099599
16CSNK1A1L2.02369394
17MAP2K42.01144142
18LATS12.00708036
19PAK61.91098687
20MAP4K21.89610300
21CSNK1G11.89054600
22NTRK11.78411480
23ARAF1.71559650
24PRKD31.56361357
25RIPK41.54651904
26CAMKK11.54562503
27PNCK1.54334078
28KSR11.50487545
29CDK191.49266544
30CDK51.45476535
31MAP3K21.40340118
32RPS6KA41.34863791
33PLK21.32888670
34GRK51.29588769
35CAMKK21.29384373
36MAPK131.28522085
37OXSR11.26283498
38AKT31.25653974
39MAP3K131.21006063
40BMPR1B1.20457131
41MYLK1.19667446
42DAPK11.17045866
43EIF2AK31.16785333
44PRKCG1.15522596
45SGK4941.14162551
46SGK2231.14162551
47TNIK1.13518116
48CAMK2A1.12992319
49OBSCN1.10787601
50PRPF4B1.08498704
51NEK21.06742122
52PHKG11.06168465
53PHKG21.06168465
54DYRK21.03118639
55CDK31.02791054
56SIK21.01586536
57STK381.01350347
58DYRK30.99861644
59ZAK0.99675108
60MARK30.96450499
61LATS20.94774964
62SRPK10.94323409
63SGK20.93857042
64FES0.93250069
65UHMK10.92957570
66CAMK2B0.92921959
67TYRO30.91085394
68LMTK20.85393243
69PAK30.85080793
70CSNK1G20.83624941
71TIE10.83210624
72RET0.80668951
73CDK140.79768908
74CDK180.77691104
75GRK10.75476119
76CAMK10.74982997
77STK110.74809158
78CDK150.74748694
79EPHA30.74031612
80MAP3K10.73848520
81STK390.73369476
82FER0.73013842
83PINK10.72576725
84BCR0.72217536
85WNK30.70426192
86PRKCH0.69926044
87PRKCE0.69890058
88SGK30.69649451
89BMPR20.69598834
90BRAF0.69449108
91DYRK1A0.68570701
92FGFR20.66412269
93PTK2B0.65928161
94CAMK2D0.65208403
95CCNB10.63922321
96RPS6KB10.63584843
97RAF10.61947227
98CDK11A0.61503801
99TAOK10.61445138
100SGK10.60318232
101FRK0.59782372
102CAMK2G0.59341860
103MAP2K10.59104394
104PDPK10.58654459
105WNK10.58485916
106ERBB30.57450904
107PLK30.54941847
108MARK20.54843392
109PRKCZ0.54815347
110PDK10.54075447
111PKN20.52601199
112WNK40.51492197
113CAMK1G0.49286257
114CSNK1D0.48814802
115INSRR0.48291743
116RPS6KA50.48194483
117MAP3K50.44985058
118SIK30.44637167
119CSNK1A10.44425452
120RPS6KA30.44020113
121MAP3K60.42683797
122MUSK0.42035232
123BRD40.41771005
124FYN0.40424005
125NEK60.38801063
126GRK70.38639363
127PDK40.38567995
128PDK30.38567995
129MAPK100.37890794
130TSSK60.37730451
131TNK20.37692973
132ADRBK10.36988014
133STK30.36402949
134ROCK10.35469676
135MKNK20.33287483
136CSNK1E0.33202414
137PRKG10.31811568
138ATM0.30898619
139PRKACB0.30845373
140ADRBK20.30501911
141PRKAA10.28601107
142LIMK10.28534658

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.64492463
2Synaptic vesicle cycle_Homo sapiens_hsa047213.38889904
3GABAergic synapse_Homo sapiens_hsa047272.72099307
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.58347390
5Olfactory transduction_Homo sapiens_hsa047402.53047227
6Circadian entrainment_Homo sapiens_hsa047132.44027954
7Morphine addiction_Homo sapiens_hsa050322.37324780
8Glutamatergic synapse_Homo sapiens_hsa047242.32952182
9Long-term potentiation_Homo sapiens_hsa047202.32095675
10Amphetamine addiction_Homo sapiens_hsa050312.28183312
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.08692336
12Dopaminergic synapse_Homo sapiens_hsa047282.06972376
13Salivary secretion_Homo sapiens_hsa049702.02976463
14Insulin secretion_Homo sapiens_hsa049112.02552062
15Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.96703074
16Collecting duct acid secretion_Homo sapiens_hsa049661.89790010
17Taste transduction_Homo sapiens_hsa047421.79562266
18Serotonergic synapse_Homo sapiens_hsa047261.79304699
19Cholinergic synapse_Homo sapiens_hsa047251.76346246
20Cocaine addiction_Homo sapiens_hsa050301.74650487
21Gastric acid secretion_Homo sapiens_hsa049711.72132431
22Maturity onset diabetes of the young_Homo sapiens_hsa049501.70224154
23Renin secretion_Homo sapiens_hsa049241.70082646
24Long-term depression_Homo sapiens_hsa047301.65783616
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.58100213
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53881238
27Phototransduction_Homo sapiens_hsa047441.52291187
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46743055
29Oxytocin signaling pathway_Homo sapiens_hsa049211.44554069
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41735393
31Calcium signaling pathway_Homo sapiens_hsa040201.39188457
32Vibrio cholerae infection_Homo sapiens_hsa051101.33969162
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.30120667
34GnRH signaling pathway_Homo sapiens_hsa049121.24552064
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.24093501
36Propanoate metabolism_Homo sapiens_hsa006401.23546073
37Protein export_Homo sapiens_hsa030601.21881640
38Gap junction_Homo sapiens_hsa045401.21323019
39Hedgehog signaling pathway_Homo sapiens_hsa043401.16326148
40Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15031461
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.14999871
42cAMP signaling pathway_Homo sapiens_hsa040241.12083673
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07783569
44Axon guidance_Homo sapiens_hsa043601.05082363
45Type II diabetes mellitus_Homo sapiens_hsa049301.04165462
46Estrogen signaling pathway_Homo sapiens_hsa049151.02652552
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02469880
48Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98522336
49beta-Alanine metabolism_Homo sapiens_hsa004100.94871033
50Regulation of autophagy_Homo sapiens_hsa041400.94459496
51Cardiac muscle contraction_Homo sapiens_hsa042600.93648252
52Nitrogen metabolism_Homo sapiens_hsa009100.92620982
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91473438
54Pancreatic secretion_Homo sapiens_hsa049720.90650528
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.90344168
56ErbB signaling pathway_Homo sapiens_hsa040120.89903925
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89545495
58Steroid biosynthesis_Homo sapiens_hsa001000.89514598
59Glioma_Homo sapiens_hsa052140.87633029
60Melanogenesis_Homo sapiens_hsa049160.86540818
61Basal transcription factors_Homo sapiens_hsa030220.83946612
62Thyroid hormone synthesis_Homo sapiens_hsa049180.79418249
63Arginine biosynthesis_Homo sapiens_hsa002200.79141354
64Dorso-ventral axis formation_Homo sapiens_hsa043200.78873037
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.78343857
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77926354
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75698900
68Hippo signaling pathway_Homo sapiens_hsa043900.74050606
69Tight junction_Homo sapiens_hsa045300.70867760
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68958297
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.68326129
72Vitamin B6 metabolism_Homo sapiens_hsa007500.67434634
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65186221
74AMPK signaling pathway_Homo sapiens_hsa041520.64778337
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64631504
76Circadian rhythm_Homo sapiens_hsa047100.64157088
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62599801
78Bile secretion_Homo sapiens_hsa049760.62501932
79Folate biosynthesis_Homo sapiens_hsa007900.62181398
80Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60861457
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60736923
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59984639
83Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59809246
84Oocyte meiosis_Homo sapiens_hsa041140.58965035
85Selenocompound metabolism_Homo sapiens_hsa004500.58911403
86Choline metabolism in cancer_Homo sapiens_hsa052310.58852659
87Dilated cardiomyopathy_Homo sapiens_hsa054140.58796967
88MAPK signaling pathway_Homo sapiens_hsa040100.55941116
89Prion diseases_Homo sapiens_hsa050200.55807713
90Sphingolipid metabolism_Homo sapiens_hsa006000.53045685
91Butanoate metabolism_Homo sapiens_hsa006500.52614236
92Ras signaling pathway_Homo sapiens_hsa040140.51778044
93TGF-beta signaling pathway_Homo sapiens_hsa043500.51075246
94Glucagon signaling pathway_Homo sapiens_hsa049220.50624194
95Type I diabetes mellitus_Homo sapiens_hsa049400.50504853
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49436818
97Alzheimers disease_Homo sapiens_hsa050100.49112159
98Ovarian steroidogenesis_Homo sapiens_hsa049130.48081711
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47403954
100Peroxisome_Homo sapiens_hsa041460.46769680
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46744749
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46650081
103Inositol phosphate metabolism_Homo sapiens_hsa005620.46559572
104Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.45914294
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45547504
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.43536817
107Oxidative phosphorylation_Homo sapiens_hsa001900.43363884
108Renal cell carcinoma_Homo sapiens_hsa052110.43283945
109Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.43056942
110Rap1 signaling pathway_Homo sapiens_hsa040150.42406911
111Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42356496
112RNA degradation_Homo sapiens_hsa030180.41805839
113Pyruvate metabolism_Homo sapiens_hsa006200.41721791
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41611347
115VEGF signaling pathway_Homo sapiens_hsa043700.40740776
116Endocytosis_Homo sapiens_hsa041440.39539346
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38612316
118Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38491888
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.38085870
120Fatty acid metabolism_Homo sapiens_hsa012120.37777459
121Arginine and proline metabolism_Homo sapiens_hsa003300.37129354
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.36883982
123Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.35991760
124Alcoholism_Homo sapiens_hsa050340.35937404
125Rheumatoid arthritis_Homo sapiens_hsa053230.35658628
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35256948
127Mineral absorption_Homo sapiens_hsa049780.35111315
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33251834
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32650318
130mTOR signaling pathway_Homo sapiens_hsa041500.32257017
131Endometrial cancer_Homo sapiens_hsa052130.31495358
132Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.29259035
133Wnt signaling pathway_Homo sapiens_hsa043100.29103918
134Insulin signaling pathway_Homo sapiens_hsa049100.28954472

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