SCAMP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1polyketide metabolic process (GO:0030638)5.35251043
2doxorubicin metabolic process (GO:0044598)5.35251043
3daunorubicin metabolic process (GO:0044597)5.35251043
4regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.25498373
5neutrophil activation involved in immune response (GO:0002283)4.21108469
6positive regulation of gamma-delta T cell activation (GO:0046645)4.17601847
7aminoglycoside antibiotic metabolic process (GO:0030647)4.10651328
8immunoglobulin mediated immune response (GO:0016064)3.94919383
9response to peptidoglycan (GO:0032494)3.75308991
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.68888242
11negative regulation of cell killing (GO:0031342)3.68888242
12cytidine metabolic process (GO:0046087)3.62034584
13cytidine catabolic process (GO:0006216)3.62034584
14cytidine deamination (GO:0009972)3.62034584
15negative regulation of erythrocyte differentiation (GO:0045647)3.58720387
16detection of bacterium (GO:0016045)3.56633255
17antigen processing and presentation of endogenous antigen (GO:0019883)3.54865751
18detection of other organism (GO:0098543)3.51420609
19antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.45758061
20keratan sulfate catabolic process (GO:0042340)3.43183011
21signal peptide processing (GO:0006465)3.41215708
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.38524237
23antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.38524237
24positive regulation of antigen processing and presentation (GO:0002579)3.36801680
25modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.35542618
26positive regulation by organism of defense response of other organism involved in symbiotic interact3.35542618
27modulation by symbiont of host immune response (GO:0052553)3.35542618
28positive regulation by symbiont of host defense response (GO:0052509)3.35542618
29modulation by symbiont of host defense response (GO:0052031)3.35542618
30modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.35542618
31response to muramyl dipeptide (GO:0032495)3.34524459
32regulation of antigen processing and presentation (GO:0002577)3.22776719
33respiratory burst (GO:0045730)3.20264405
34negative regulation of phagocytosis (GO:0050765)3.15719122
35regulation of interferon-beta biosynthetic process (GO:0045357)3.14805237
36microglial cell activation (GO:0001774)3.14391993
37negative regulation of interleukin-12 production (GO:0032695)3.13732087
38neutrophil activation (GO:0042119)3.13688566
39phagocytosis, engulfment (GO:0006911)3.12081882
40regulation of gamma-delta T cell activation (GO:0046643)3.05161410
41regulation of response to osmotic stress (GO:0047484)2.99237180
42granulocyte activation (GO:0036230)2.98765722
43negative regulation of bone resorption (GO:0045779)2.98439714
44regulation of B cell receptor signaling pathway (GO:0050855)2.97936484
45amyloid precursor protein catabolic process (GO:0042987)2.95590781
46Arp2/3 complex-mediated actin nucleation (GO:0034314)2.95579174
47G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.94460516
48positive regulation of chemokine secretion (GO:0090197)2.94059955
49positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.92971839
50regulation of apoptotic process involved in morphogenesis (GO:1902337)2.90519630
51regulation of mast cell degranulation (GO:0043304)2.90478968
52regulation of gamma-delta T cell differentiation (GO:0045586)2.87897908
53barbed-end actin filament capping (GO:0051016)2.87559104
54B cell mediated immunity (GO:0019724)2.87335160
55pinocytosis (GO:0006907)2.86667642
56macrophage activation involved in immune response (GO:0002281)2.85585715
57regulation of chemokine secretion (GO:0090196)2.84734690
58myeloid dendritic cell differentiation (GO:0043011)2.81526898
59positive thymic T cell selection (GO:0045059)2.79857787
60regulation of leukocyte degranulation (GO:0043300)2.79713812
61leukocyte aggregation (GO:0070486)2.79368148
62positive regulation of interferon-alpha production (GO:0032727)2.78379958
63positive regulation of defense response to virus by host (GO:0002230)2.78233096
64detection of external biotic stimulus (GO:0098581)2.78185749
65cyclooxygenase pathway (GO:0019371)2.74443439
66interferon-gamma production (GO:0032609)2.73857952
67membrane protein intracellular domain proteolysis (GO:0031293)2.73506579
68regulation of T cell tolerance induction (GO:0002664)2.73295802
69regulation of myeloid leukocyte mediated immunity (GO:0002886)2.71804553
70regulation of superoxide anion generation (GO:0032928)2.70811096
71positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.69287576
72NIK/NF-kappaB signaling (GO:0038061)2.68411657
73maintenance of protein location in nucleus (GO:0051457)2.65756106
74regulation of tolerance induction (GO:0002643)2.65528042
75regulation of interferon-alpha production (GO:0032647)2.62260876
76positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.62144171
77nucleoside transmembrane transport (GO:1901642)2.60744791
78positive regulation of Cdc42 GTPase activity (GO:0043089)2.60683689
79negative regulation of interleukin-2 production (GO:0032703)2.59008894
80positive regulation of B cell differentiation (GO:0045579)2.57498048
81positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.55541521
82response to host immune response (GO:0052572)2.55100759
83response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.55100759
84thymic T cell selection (GO:0045061)2.54458076
85hyaluronan catabolic process (GO:0030214)2.54336151
86amino sugar catabolic process (GO:0046348)2.53734515
87myeloid cell activation involved in immune response (GO:0002275)2.53188897
88regulation of mast cell activation involved in immune response (GO:0033006)2.53119717
89mannose metabolic process (GO:0006013)2.53016089
90negative regulation of cytokine production involved in immune response (GO:0002719)2.52628658
91pyrimidine ribonucleoside catabolic process (GO:0046133)2.52196111
92glycosphingolipid catabolic process (GO:0046479)2.51002059
93regulation of dendritic cell antigen processing and presentation (GO:0002604)2.49404108
94oligosaccharide catabolic process (GO:0009313)2.48843382
95negative thymic T cell selection (GO:0045060)2.48404804
96regulation of podosome assembly (GO:0071801)2.47825207
97somite rostral/caudal axis specification (GO:0032525)2.47323482
98ribosomal small subunit biogenesis (GO:0042274)2.45915554
99defense response to protozoan (GO:0042832)2.45702664
100response to host (GO:0075136)2.45652675
101response to host defenses (GO:0052200)2.45652675
102response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.45652675
103positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.45262990
104negative regulation of tissue remodeling (GO:0034104)2.45019256
105negative regulation of interleukin-6 production (GO:0032715)2.43391788
106regulation of interleukin-2 biosynthetic process (GO:0045076)2.42702693
107reactive oxygen species biosynthetic process (GO:1903409)2.41815831
108T cell selection (GO:0045058)2.41794900
109regulation of B cell differentiation (GO:0045577)2.41302146
110germinal center formation (GO:0002467)2.41123139
111response to protozoan (GO:0001562)2.40166087
112dendritic cell differentiation (GO:0097028)2.39991069
113antigen processing and presentation via MHC class Ib (GO:0002475)2.39757427
114negative regulation of innate immune response (GO:0045824)2.39217031
115negative regulation of myeloid cell apoptotic process (GO:0033033)2.38258297
116positive regulation of tumor necrosis factor production (GO:0032760)2.37820328
117negative T cell selection (GO:0043383)2.36586024
118glycoside metabolic process (GO:0016137)2.36276831
119GDP-mannose metabolic process (GO:0019673)2.36052288
120response to interferon-beta (GO:0035456)2.36045658
121negative regulation of leukocyte mediated immunity (GO:0002704)2.35851574
122T cell migration (GO:0072678)2.35666792
123detection of biotic stimulus (GO:0009595)2.35161844
124interferon-gamma-mediated signaling pathway (GO:0060333)2.35160634
125COPI coating of Golgi vesicle (GO:0048205)2.35106826
126Golgi transport vesicle coating (GO:0048200)2.35106826
127negative regulation of telomerase activity (GO:0051974)2.34488172
128cellular response to interferon-gamma (GO:0071346)2.34054996
129purinergic nucleotide receptor signaling pathway (GO:0035590)2.34010570
130B cell receptor signaling pathway (GO:0050853)2.33641291
131T-helper 1 type immune response (GO:0042088)2.33396545
132cellular extravasation (GO:0045123)2.33195838
133positive regulation of interleukin-17 production (GO:0032740)2.32839755
134regulation of necroptotic process (GO:0060544)2.31717449
135myeloid dendritic cell activation (GO:0001773)2.31445060
136actin nucleation (GO:0045010)2.31412039
137glycolipid catabolic process (GO:0019377)2.31084856
138cellular response to type I interferon (GO:0071357)2.31063322
139type I interferon signaling pathway (GO:0060337)2.31063322
140peptide catabolic process (GO:0043171)2.30555482
141negative regulation of bone remodeling (GO:0046851)2.30398170
142regulation of natural killer cell mediated immunity (GO:0002715)2.30235717
143regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.30235717
144regulation of defense response to virus by virus (GO:0050690)2.29726542
145hydrogen peroxide biosynthetic process (GO:0050665)2.29318798
146ceramide catabolic process (GO:0046514)2.29175146
147regulation of macrophage chemotaxis (GO:0010758)2.29117128
148negative regulation of epidermis development (GO:0045683)2.28657499
149hormone catabolic process (GO:0042447)2.28476278
150response to type I interferon (GO:0034340)2.27384937
151leukotriene metabolic process (GO:0006691)2.26315751
152lipopolysaccharide-mediated signaling pathway (GO:0031663)2.26227426
153regulation of RIG-I signaling pathway (GO:0039535)2.25595212
154cellular response to interferon-beta (GO:0035458)2.25508440
155muscle organ morphogenesis (GO:0048644)2.25464046
156positive regulation of keratinocyte differentiation (GO:0045618)2.22589717
157negative regulation of granulocyte differentiation (GO:0030853)2.21572629

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.44289304
2IRF8_21731497_ChIP-ChIP_J774_Mouse3.92529398
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.69750940
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.07083748
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.94729450
6KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.89423109
7KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.89423109
8KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.89423109
9* IRF8_27001747_Chip-Seq_BMDM_Mouse2.61859926
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.50566698
11SCL_19346495_ChIP-Seq_HPC-7_Human2.39541984
12* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.37910163
13NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.26927027
14* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.26899909
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.16863072
16NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.10253236
17SPI1_23547873_ChIP-Seq_NB4_Human2.10153021
18LXR_22292898_ChIP-Seq_THP-1_Human2.07725492
19TP63_17297297_ChIP-ChIP_HaCaT_Human2.04547221
20PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.97621706
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.87435194
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86516740
23FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.82269386
24* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.80561816
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.79296420
26RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.76828055
27STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.73065594
28RARG_19884340_ChIP-ChIP_MEFs_Mouse1.72123268
29STAT4_19710469_ChIP-ChIP_TH1__Mouse1.68618343
30STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.67906286
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.65876435
32* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64688421
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.64189336
34IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.63185544
35KDM2B_26808549_Chip-Seq_SUP-B15_Human1.62806595
36NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.62247192
37RACK7_27058665_Chip-Seq_MCF-7_Human1.61167139
38VDR_21846776_ChIP-Seq_THP-1_Human1.60801388
39TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59613500
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.59472266
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.58581781
42STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.55597675
43* MYB_26560356_Chip-Seq_TH2_Human1.55246991
44RUNX1_22412390_ChIP-Seq_EML_Mouse1.54527235
45TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.54094975
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.50397629
47NOTCH1_21737748_ChIP-Seq_TLL_Human1.49135650
48ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.48283162
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.44307721
50MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.44181006
51CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.41999682
52SPI1_23127762_ChIP-Seq_K562_Human1.41658539
53VDR_24763502_ChIP-Seq_THP-1_Human1.40149806
54PPARA_22158963_ChIP-Seq_LIVER_Mouse1.38647724
55KDM2B_26808549_Chip-Seq_DND41_Human1.37629463
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37540055
57Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.36866383
58RXR_22158963_ChIP-Seq_LIVER_Mouse1.34379290
59PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.33809893
60SRY_22984422_ChIP-ChIP_TESTIS_Rat1.31209539
61* MYB_26560356_Chip-Seq_TH1_Human1.31151227
62* MAF_26560356_Chip-Seq_TH1_Human1.30200733
63* BCL6_27268052_Chip-Seq_Bcells_Human1.29931806
64SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28471690
65* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.26784464
66E2F7_22180533_ChIP-Seq_HELA_Human1.26217876
67* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.24783835
68RUNX_20019798_ChIP-Seq_JUKART_Human1.24307479
69GATA1_19941827_ChIP-Seq_MEL_Mouse1.24109967
70KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.22250589
71ZNF263_19887448_ChIP-Seq_K562_Human1.22082781
72ELF1_20517297_ChIP-Seq_JURKAT_Human1.21021067
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19169143
74PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.18887694
75CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16643599
76PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16631434
77MYC_22102868_ChIP-Seq_BL_Human1.16036883
78NCOR1_26117541_ChIP-Seq_K562_Human1.15657673
79LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.15017360
80CTCF_27219007_Chip-Seq_ERYTHROID_Human1.14132179
81* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13239179
82FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.13081385
83CDX2_20551321_ChIP-Seq_CACO-2_Human1.12663833
84GATA1_19941826_ChIP-Seq_K562_Human1.12084431
85* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12032318
86KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.11971977
87P68_20966046_ChIP-Seq_HELA_Human1.11624714
88GATA1_22383799_ChIP-Seq_G1ME_Mouse1.10932485
89KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10628958
90VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10216586
91SA1_27219007_Chip-Seq_ERYTHROID_Human1.10126828
92TET1_21451524_ChIP-Seq_MESCs_Mouse1.09240873
93TCF7_22412390_ChIP-Seq_EML_Mouse1.08478346
94TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08309097
95KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.08307251
96GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.08262853
97CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05244409
98P63_26484246_Chip-Seq_KERATINOCYTES_Human1.03537134
99EGR1_19374776_ChIP-ChIP_THP-1_Human1.02680641
100NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02110588
101CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.01986187
102PU_27001747_Chip-Seq_BMDM_Mouse1.01698261
103ESR2_21235772_ChIP-Seq_MCF-7_Human1.01228834
104* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.00357238
105CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00156681
106* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.00084619
107TFEB_21752829_ChIP-Seq_HELA_Human1.00041442
108TCF3_18692474_ChIP-Seq_MEFs_Mouse0.99825637
109UTX_26944678_Chip-Seq_JUKART_Human0.98848362
110EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.97692299
111GATA3_27048872_Chip-Seq_THYMUS_Human0.97245181
112FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.95357738
113KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94376610
114GATA1_22025678_ChIP-Seq_K562_Human0.92740011
115POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91612935
116STAT3_1855785_ChIP-Seq_MESCs_Mouse0.90951175
117GABP_17652178_ChIP-ChIP_JURKAT_Human0.90776202
118MAF_26560356_Chip-Seq_TH2_Human0.90360412
119GATA2_21666600_ChIP-Seq_HMVEC_Human0.90232556
120EST1_17652178_ChIP-ChIP_JURKAT_Human0.90079208
121CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.89673600
122PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88047522
123* ELK3_25401928_ChIP-Seq_HUVEC_Human0.87995322
124ESR1_21235772_ChIP-Seq_MCF-7_Human0.85589558
125BCOR_27268052_Chip-Seq_Bcells_Human0.85533162
126PU.1_20513432_ChIP-Seq_Bcells_Mouse0.84315548
127HOXB4_20404135_ChIP-ChIP_EML_Mouse0.83762293
128* GATA3_26560356_Chip-Seq_TH2_Human0.83458652
129CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.83384674
130STAT1_20625510_ChIP-Seq_HELA_Human0.83289310
131GATA4_25053715_ChIP-Seq_YYC3_Human0.82857764
132* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82700736
133FOXO3_23340844_ChIP-Seq_DLD1_Human0.82605849
134CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82133747

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.78458331
2MP0002254_reproductive_system_inflammat3.10414072
3MP0006082_CNS_inflammation3.04934127
4MP0003436_decreased_susceptibility_to2.87971344
5MP0005671_abnormal_response_to2.67311947
6MP0002148_abnormal_hypersensitivity_rea2.60726689
7MP0005058_abnormal_lysosome_morphology2.58206888
8MP0005000_abnormal_immune_tolerance2.52590023
9MP0000685_abnormal_immune_system2.38386849
10MP0004264_abnormal_extraembryonic_tissu2.37606062
11MP0005387_immune_system_phenotype2.37218930
12MP0001790_abnormal_immune_system2.37218930
13MP0009785_altered_susceptibility_to2.31135603
14MP0003183_abnormal_peptide_metabolism2.29918142
15MP0005025_abnormal_response_to2.29633431
16MP0002419_abnormal_innate_immunity2.28271713
17MP0002452_abnormal_antigen_presenting2.15205052
18MP0001800_abnormal_humoral_immune2.14588150
19MP0005451_abnormal_body_composition2.12689432
20MP0003011_delayed_dark_adaptation2.06738309
21MP0002723_abnormal_immune_serum2.02895096
22MP0003172_abnormal_lysosome_physiology2.00518165
23MP0001819_abnormal_immune_cell1.95385129
24MP0002420_abnormal_adaptive_immunity1.95294592
25MP0003724_increased_susceptibility_to1.83934635
26MP0005075_abnormal_melanosome_morpholog1.82635963
27MP0003191_abnormal_cellular_cholesterol1.82378007
28MP0005310_abnormal_salivary_gland1.73845614
29MP0009333_abnormal_splenocyte_physiolog1.73321662
30MP0002139_abnormal_hepatobiliary_system1.71323285
31MP0002405_respiratory_system_inflammati1.70874880
32MP0010155_abnormal_intestine_physiology1.70727881
33MP0008260_abnormal_autophagy1.70240525
34MP0002396_abnormal_hematopoietic_system1.69546892
35MP0002277_abnormal_respiratory_mucosa1.68604572
36MP0001853_heart_inflammation1.67115185
37MP0001533_abnormal_skeleton_physiology1.63960257
38MP0003806_abnormal_nucleotide_metabolis1.53887327
39MP0001845_abnormal_inflammatory_respons1.53463437
40MP0000490_abnormal_crypts_of1.51311914
41MP0000343_altered_response_to1.49214791
42MP0000716_abnormal_immune_system1.48815112
43MP0005464_abnormal_platelet_physiology1.47292538
44MP0003303_peritoneal_inflammation1.47088018
45MP0009278_abnormal_bone_marrow1.44299568
46MP0003300_gastrointestinal_ulcer1.41361728
47MP0000689_abnormal_spleen_morphology1.36411057
48MP0002398_abnormal_bone_marrow1.34432754
49MP0004947_skin_inflammation1.32805683
50MP0005257_abnormal_intraocular_pressure1.32454846
51MP0008469_abnormal_protein_level1.28563436
52MP0002429_abnormal_blood_cell1.28405097
53MP0002877_abnormal_melanocyte_morpholog1.27942283
54MP0010234_abnormal_vibrissa_follicle1.26954752
55MP0003763_abnormal_thymus_physiology1.26378689
56MP0004782_abnormal_surfactant_physiolog1.26162573
57MP0000858_altered_metastatic_potential1.25290322
58MP0002722_abnormal_immune_system1.24623827
59MP0009840_abnormal_foam_cell1.23765611
60MP0005166_decreased_susceptibility_to1.21059880
61MP0005360_urolithiasis1.20855050
62MP0001348_abnormal_lacrimal_gland1.19694903
63MP0000465_gastrointestinal_hemorrhage1.19400796
64MP0002166_altered_tumor_susceptibility1.18885997
65MP0003448_altered_tumor_morphology1.17795747
66MP0000604_amyloidosis1.15003979
67MP0001851_eye_inflammation1.13413703
68MP0001873_stomach_inflammation1.12267044
69MP0000678_abnormal_parathyroid_gland1.09979549
70MP0004381_abnormal_hair_follicle1.08380638
71MP0004510_myositis1.08034311
72MP0005365_abnormal_bile_salt1.07471211
73MP0002933_joint_inflammation1.04792331
74MP0005390_skeleton_phenotype1.00509248
75MP0001663_abnormal_digestive_system0.99954804
76MP0003186_abnormal_redox_activity0.94810579
77MP0002998_abnormal_bone_remodeling0.94653282
78MP0010352_gastrointestinal_tract_polyps0.94154063
79MP0003705_abnormal_hypodermis_morpholog0.92403410
80MP0002098_abnormal_vibrissa_morphology0.91748213
81MP0009643_abnormal_urine_homeostasis0.91303907
82MP0009763_increased_sensitivity_to0.90332672
83MP0005023_abnormal_wound_healing0.89330216
84MP0003795_abnormal_bone_structure0.88722490
85MP0002006_tumorigenesis0.87022499
86MP0003866_abnormal_defecation0.86500051
87MP0005165_increased_susceptibility_to0.86085500
88MP0005164_abnormal_response_to0.84774437
89MP0003075_altered_response_to0.81968922
90MP0009764_decreased_sensitivity_to0.81419385
91MP0008057_abnormal_DNA_replication0.81228725
92MP0005319_abnormal_enzyme/_coenzyme0.81129338
93MP0002138_abnormal_hepatobiliary_system0.81022802
94MP0005501_abnormal_skin_physiology0.79943076
95MP0004858_abnormal_nervous_system0.79825816
96MP0000609_abnormal_liver_physiology0.79819385
97MP0008007_abnormal_cellular_replicative0.79554585
98MP0002136_abnormal_kidney_physiology0.79440713
99MP0006054_spinal_hemorrhage0.78228350
100MP0003453_abnormal_keratinocyte_physiol0.78204670
101MP0002132_abnormal_respiratory_system0.77981088
102MP0000383_abnormal_hair_follicle0.77382172
103MP0001666_abnormal_nutrient_absorption0.76294796
104MP0004883_abnormal_blood_vessel0.75507065
105MP0000920_abnormal_myelination0.75193080
106MP0002796_impaired_skin_barrier0.74156193
107MP0003566_abnormal_cell_adhesion0.73876235
108MP0003690_abnormal_glial_cell0.73726045
109MP0001216_abnormal_epidermal_layer0.73672312
110MP0000249_abnormal_blood_vessel0.73052838
111MP0005381_digestive/alimentary_phenotyp0.71561894
112MP0004808_abnormal_hematopoietic_stem0.70552928
113MP0006292_abnormal_olfactory_placode0.70212489
114MP0005584_abnormal_enzyme/coenzyme_acti0.69898196
115MP0008004_abnormal_stomach_pH0.69438480
116MP0003693_abnormal_embryo_hatching0.67543113
117MP0004043_abnormal_pH_regulation0.66155530
118MP0000377_abnormal_hair_follicle0.65322012
119MP0005174_abnormal_tail_pigmentation0.63991078
120MP0001849_ear_inflammation0.62380100
121MP0000703_abnormal_thymus_morphology0.60896656
122MP0004957_abnormal_blastocyst_morpholog0.60856411
123MP0003828_pulmonary_edema0.60266989
124MP0001545_abnormal_hematopoietic_system0.58648639
125MP0005397_hematopoietic_system_phenotyp0.58648639

Predicted human phenotypes

RankGene SetZ-score
1Vacuolated lymphocytes (HP:0001922)5.18444626
2Recurrent abscess formation (HP:0002722)4.75027603
3Abnormality of glycolipid metabolism (HP:0010969)4.38585213
4Abnormality of liposaccharide metabolism (HP:0010968)4.38585213
5Abnormality of glycosphingolipid metabolism (HP:0004343)4.38585213
6Recurrent bacterial skin infections (HP:0005406)4.36883999
7Systemic lupus erythematosus (HP:0002725)4.08447502
8Eczematoid dermatitis (HP:0000976)3.93906239
9Elevated erythrocyte sedimentation rate (HP:0003565)3.91428636
10Abnormality of macrophages (HP:0004311)3.55288343
11Reduced antithrombin III activity (HP:0001976)3.31560270
12Myositis (HP:0100614)3.26641332
13Type I transferrin isoform profile (HP:0003642)3.22280211
14Increased neuronal autofluorescent lipopigment (HP:0002074)3.19074686
15Increased cerebral lipofuscin (HP:0011813)3.07301147
16Glomerulonephritis (HP:0000099)2.97663832
17Multiple enchondromatosis (HP:0005701)2.96911201
18Dysostosis multiplex (HP:0000943)2.95717866
19Mucopolysacchariduria (HP:0008155)2.90488725
20Urinary glycosaminoglycan excretion (HP:0003541)2.90488725
21Bilateral microphthalmos (HP:0007633)2.81616827
22Recurrent skin infections (HP:0001581)2.81218151
23Petechiae (HP:0000967)2.76057346
24Orchitis (HP:0100796)2.75507073
25IgM deficiency (HP:0002850)2.74913390
26Abnormal protein glycosylation (HP:0012346)2.67730812
27Abnormal glycosylation (HP:0012345)2.67730812
28Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.67730812
29Abnormal protein N-linked glycosylation (HP:0012347)2.67730812
30Stomatitis (HP:0010280)2.67608793
31Nasal polyposis (HP:0100582)2.67519391
32Epistaxis (HP:0000421)2.53797455
33Gingivitis (HP:0000230)2.53765125
34Abnormality of polysaccharide metabolism (HP:0011012)2.51909412
35Abnormality of glycosaminoglycan metabolism (HP:0004371)2.51909412
36Abnormality of mucopolysaccharide metabolism (HP:0011020)2.51909412
37Malnutrition (HP:0004395)2.51045206
38Abnormality of T cell physiology (HP:0011840)2.50878520
39Partial duplication of thumb phalanx (HP:0009944)2.49828078
40Chronic otitis media (HP:0000389)2.49277567
41Progressive neurologic deterioration (HP:0002344)2.47538251
42Recurrent viral infections (HP:0004429)2.44253609
43Cellulitis (HP:0100658)2.43101825
44Vertebral compression fractures (HP:0002953)2.41798750
45Abnormality of the nasal mucosa (HP:0000433)2.38529795
46Increased serum ferritin (HP:0003281)2.38131241
47Poor head control (HP:0002421)2.37966829
48Prolonged bleeding time (HP:0003010)2.35014734
49Recurrent fungal infections (HP:0002841)2.34706398
50Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.31553139
51Cheilitis (HP:0100825)2.30900746
52Recurrent gram-negative bacterial infections (HP:0005420)2.29941123
53Obstructive lung disease (HP:0006536)2.29300954
54Chronic obstructive pulmonary disease (HP:0006510)2.29300954
55Gingival bleeding (HP:0000225)2.29104917
56Abnormality of small intestinal villus morphology (HP:0011472)2.20191039
57Villous atrophy (HP:0011473)2.20191039
58Abnormal delayed hypersensitivity skin test (HP:0002963)2.16127559
59Interstitial pulmonary disease (HP:0006530)2.15579463
60Partial duplication of the phalanx of hand (HP:0009999)2.13467409
61Cervical subluxation (HP:0003308)2.13454949
62Vasculitis (HP:0002633)2.13040597
63Autoimmune thrombocytopenia (HP:0001973)2.12968037
64Trismus (HP:0000211)2.10039824
65Pustule (HP:0200039)2.08872217
66Gastrointestinal infarctions (HP:0005244)2.08617887
67Periodontitis (HP:0000704)2.08293997
68Gastrointestinal inflammation (HP:0004386)2.07508400
69Autoimmune hemolytic anemia (HP:0001890)2.07203171
70Chest pain (HP:0100749)2.06679650
71Optic neuritis (HP:0100653)2.05365231
72Retrobulbar optic neuritis (HP:0100654)2.05365231
73Hepatosplenomegaly (HP:0001433)2.04220836
74Loss of speech (HP:0002371)2.03122636
75Abnormality of iron homeostasis (HP:0011031)2.03096960
76Hypertensive crisis (HP:0100735)2.02502749
77Pulmonary infiltrates (HP:0002113)2.01012488
78Thrombocytosis (HP:0001894)2.00977041
79Thoracic kyphosis (HP:0002942)2.00487718
80Inflammation of the large intestine (HP:0002037)2.00181742
81Reticulocytopenia (HP:0001896)1.97062798
82T lymphocytopenia (HP:0005403)1.96324307
83Gastrointestinal stroma tumor (HP:0100723)1.95656451
84Abnormality of complement system (HP:0005339)1.95567072
85Mediastinal lymphadenopathy (HP:0100721)1.95499715
86Encephalitis (HP:0002383)1.95474516
87Hemorrhage of the eye (HP:0011885)1.93801422
88Prolonged neonatal jaundice (HP:0006579)1.93600093
89Meningitis (HP:0001287)1.93363180
90Rib fusion (HP:0000902)1.92593694
91Aplasia/Hypoplasia of the sacrum (HP:0008517)1.92441070
92Hypergammaglobulinemia (HP:0010702)1.92173662
93Purpura (HP:0000979)1.91510581
94Colitis (HP:0002583)1.90917775
95Premature loss of primary teeth (HP:0006323)1.90499941
96Recurrent bronchitis (HP:0002837)1.90439623
97Urticaria (HP:0001025)1.88948201
98Hemoptysis (HP:0002105)1.88748011
99Abnormality of T cell number (HP:0011839)1.88747679
100Recurrent cutaneous fungal infections (HP:0011370)1.87970086
101Chronic mucocutaneous candidiasis (HP:0002728)1.87970086
102Complement deficiency (HP:0004431)1.87807816
103Restrictive lung disease (HP:0002091)1.87238377
104Spontaneous hematomas (HP:0007420)1.86899272
105Upper limb muscle weakness (HP:0003484)1.85672743
106Chronic diarrhea (HP:0002028)1.85254490
107Skin ulcer (HP:0200042)1.85150326
108J-shaped sella turcica (HP:0002680)1.83463785
109Abnormal number of erythroid precursors (HP:0012131)1.83165749
110Agammaglobulinemia (HP:0004432)1.83036967
111Aplasia/Hypoplasia of the fovea (HP:0008060)1.82915942
112Hypoplasia of the fovea (HP:0007750)1.82915942
113Polygenic inheritance (HP:0010982)1.82310931
114Skin rash (HP:0000988)1.81570180
115Axonal loss (HP:0003447)1.81558349
116Increased IgM level (HP:0003496)1.80158227
117Hyperinsulinemic hypoglycemia (HP:0000825)1.80123773
118Basal ganglia calcification (HP:0002135)1.79185802
119Polycythemia (HP:0001901)1.78495435
120Bone pain (HP:0002653)1.77547634
121Amyloidosis (HP:0011034)1.77485963
122Recurrent pneumonia (HP:0006532)1.77364598
123Granulocytopenia (HP:0001913)1.76603064
124Disinhibition (HP:0000734)1.76253288
125Leukocytosis (HP:0001974)1.76070894
126Distal lower limb muscle weakness (HP:0009053)1.75558901
127Eosinophilia (HP:0001880)1.74421656
128Abnormality of the distal phalanges of the toes (HP:0010182)1.72910575
129Osteomyelitis (HP:0002754)1.71518868
130Abnormality of cells of the erythroid lineage (HP:0012130)1.71285225
131Abnormality of T cells (HP:0002843)1.70840240
132Rectovaginal fistula (HP:0000143)1.70807359
133Rectal fistula (HP:0100590)1.70807359
134Ulnar deviation of the wrist (HP:0003049)1.70087533
135Increased IgE level (HP:0003212)1.69924592
136Pulmonary embolism (HP:0002204)1.68531788
137Hypertriglyceridemia (HP:0002155)1.66591047

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.54994438
2TGFBR23.91437566
3BLK3.05823938
4CSF1R3.03934581
5CDK122.88023790
6IRAK42.63064426
7PRPF4B2.48247683
8STK102.39805399
9IRAK32.31221906
10SMG12.28108736
11TRIB32.20647445
12MAP4K12.20527591
13GRK62.18683109
14EPHB12.05909285
15TYK22.01877574
16MAP3K141.88702949
17IKBKB1.88041630
18KIT1.86334338
19MATK1.83343853
20GRK71.82796369
21TBK11.71665181
22MAP3K111.71176276
23GRK11.67391397
24SIK11.65696797
25ADRBK21.62994126
26MST41.62163478
27MAPK151.61973509
28MAP3K31.61083250
29GRK51.59748945
30BTK1.53191525
31TAOK21.52582597
32CSK1.52303889
33PAK41.46373089
34ITK1.44444183
35SIK31.42182591
36NME21.41037579
37TAOK11.37655024
38PIM21.34078743
39MAPK71.33313823
40ZAP701.29862043
41IRAK21.26883885
42TNK21.24212168
43TEC1.24061987
44MOS1.23643126
45MAP3K131.23132734
46MAP2K31.17204734
47MAP3K11.16977927
48IKBKE1.13521002
49JAK31.12136732
50CHUK1.10957967
51CCNB11.10636670
52PRKG21.07505062
53NME11.01880323
54RIPK11.01330635
55HIPK20.99363984
56CDC42BPA0.95645397
57MAP3K100.88523190
58LCK0.88370077
59SCYL20.87708851
60LYN0.85986583
61SYK0.84890784
62ICK0.83739175
63JAK10.83537205
64TXK0.83316123
65PRKD20.83258444
66PDPK10.81907299
67MAP2K20.81346908
68LRRK20.81137050
69FGR0.75627821
70TAOK30.75288070
71HCK0.74830086
72CLK10.74800618
73EIF2AK20.73272775
74EPHA20.71941459
75PDK10.70791549
76MAP2K60.70652492
77MAPKAPK20.70557775
78NEK90.68688372
79MAPK110.67881228
80PIK3CG0.67401649
81NLK0.67371623
82IRAK10.67103286
83VRK10.65547178
84WNK10.64461967
85ARAF0.63038920
86FLT30.60653251
87MAP3K80.59199095
88CDK70.59036863
89FGFR30.58167770
90BCKDK0.58044817
91VRK20.57091603
92PIM10.56984281
93PRKCD0.56885440
94JAK20.56601899
95TTK0.56312711
96MARK30.55138350
97ABL20.54692771
98MAPKAPK30.54673338
99PBK0.52600132
100TYRO30.51480863
101RPS6KL10.50940429
102RPS6KC10.50940429
103TRPM70.50803828
104PKN20.50365063
105IGF1R0.50296995
106CDK60.49215443
107EIF2AK30.49084622
108RIPK40.48085322
109TESK10.47502006
110DYRK1B0.47479754
111DDR20.46492561
112RPS6KA40.45097068
113MAP3K20.44726060
114BMX0.43793790
115ABL10.43323246
116RPS6KA20.42814070
117MAPK40.42320256
118DAPK10.41332065
119TESK20.41054240
120MAPK120.40905564
121FGFR40.40304879
122KSR20.39098025
123GSK3A0.38407110
124FES0.37624791
125CDK40.36628829
126PTK60.36228947
127FYN0.36206171
128EEF2K0.34952741
129BMPR20.34886610
130STK40.34716073
131KDR0.32254226
132EPHA30.31842215
133MAPKAPK50.31123894
134PASK0.31009189
135CAMK40.30610696
136YES10.28703243
137MST1R0.27938743
138PAK10.27497505
139PRKCQ0.26612422

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005114.11012171
2Glycosaminoglycan degradation_Homo sapiens_hsa005313.18364604
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006033.17238105
4Lysosome_Homo sapiens_hsa041422.26256534
5Leishmaniasis_Homo sapiens_hsa051402.25216815
6Protein export_Homo sapiens_hsa030602.14965579
7Type I diabetes mellitus_Homo sapiens_hsa049402.09236537
8Arachidonic acid metabolism_Homo sapiens_hsa005902.00783813
9Staphylococcus aureus infection_Homo sapiens_hsa051501.96912419
10Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.88001259
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.86720128
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.79504673
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.76807069
14Antigen processing and presentation_Homo sapiens_hsa046121.68271886
15Sphingolipid metabolism_Homo sapiens_hsa006001.67027894
16Legionellosis_Homo sapiens_hsa051341.64761293
17Primary immunodeficiency_Homo sapiens_hsa053401.57656283
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.56894369
19Osteoclast differentiation_Homo sapiens_hsa043801.54837168
20Ribosome_Homo sapiens_hsa030101.54415009
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.52239150
22Ether lipid metabolism_Homo sapiens_hsa005651.47390233
23Pertussis_Homo sapiens_hsa051331.46187044
24Toll-like receptor signaling pathway_Homo sapiens_hsa046201.43273590
25B cell receptor signaling pathway_Homo sapiens_hsa046621.41148318
26Hematopoietic cell lineage_Homo sapiens_hsa046401.36206561
27Measles_Homo sapiens_hsa051621.34071952
28Galactose metabolism_Homo sapiens_hsa000521.31343070
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.31149880
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.28367791
31Linoleic acid metabolism_Homo sapiens_hsa005911.26859635
32Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.21052422
33Herpes simplex infection_Homo sapiens_hsa051681.20238046
34Vitamin B6 metabolism_Homo sapiens_hsa007501.20153726
35Maturity onset diabetes of the young_Homo sapiens_hsa049501.18435358
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.15985483
37Pentose and glucuronate interconversions_Homo sapiens_hsa000401.14441891
38Toxoplasmosis_Homo sapiens_hsa051451.13254747
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10873399
40Allograft rejection_Homo sapiens_hsa053301.10743983
41Sulfur metabolism_Homo sapiens_hsa009201.10725603
42Tuberculosis_Homo sapiens_hsa051521.10653126
43Fructose and mannose metabolism_Homo sapiens_hsa000511.07219283
44Malaria_Homo sapiens_hsa051441.07209520
45Apoptosis_Homo sapiens_hsa042101.06746693
46Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05429244
47Graft-versus-host disease_Homo sapiens_hsa053321.04530059
48NOD-like receptor signaling pathway_Homo sapiens_hsa046211.04170533
49Leukocyte transendothelial migration_Homo sapiens_hsa046701.03696998
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.03553740
51Influenza A_Homo sapiens_hsa051641.01576674
52Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.97448179
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.96802318
54Folate biosynthesis_Homo sapiens_hsa007900.94073472
55N-Glycan biosynthesis_Homo sapiens_hsa005100.93770325
56Asthma_Homo sapiens_hsa053100.93143487
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90064166
58Renin-angiotensin system_Homo sapiens_hsa046140.89372094
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.88417962
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83577625
61Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78902001
62Shigellosis_Homo sapiens_hsa051310.76902550
63Complement and coagulation cascades_Homo sapiens_hsa046100.75079731
64Platelet activation_Homo sapiens_hsa046110.73222476
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72648707
66Vitamin digestion and absorption_Homo sapiens_hsa049770.72029383
67Salmonella infection_Homo sapiens_hsa051320.71824661
68Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70882087
69Vibrio cholerae infection_Homo sapiens_hsa051100.70674753
70Chronic myeloid leukemia_Homo sapiens_hsa052200.70085197
71Bladder cancer_Homo sapiens_hsa052190.69228361
72Glutathione metabolism_Homo sapiens_hsa004800.68896103
73TNF signaling pathway_Homo sapiens_hsa046680.68156519
74T cell receptor signaling pathway_Homo sapiens_hsa046600.68120220
75Phagosome_Homo sapiens_hsa041450.67852168
76Autoimmune thyroid disease_Homo sapiens_hsa053200.66787888
77Amoebiasis_Homo sapiens_hsa051460.66057579
78Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65638617
79Rheumatoid arthritis_Homo sapiens_hsa053230.64838134
80Endocytosis_Homo sapiens_hsa041440.64768221
81Prion diseases_Homo sapiens_hsa050200.63539423
82Hepatitis C_Homo sapiens_hsa051600.62794934
83Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.61446362
84RNA polymerase_Homo sapiens_hsa030200.60496164
85Non-small cell lung cancer_Homo sapiens_hsa052230.60284999
86VEGF signaling pathway_Homo sapiens_hsa043700.58775500
87Base excision repair_Homo sapiens_hsa034100.58486785
88Notch signaling pathway_Homo sapiens_hsa043300.56552357
89Chemokine signaling pathway_Homo sapiens_hsa040620.55931481
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.55710148
91Acute myeloid leukemia_Homo sapiens_hsa052210.55386942
92Pentose phosphate pathway_Homo sapiens_hsa000300.54827755
93HTLV-I infection_Homo sapiens_hsa051660.53491456
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52331479
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.51343759
96Regulation of autophagy_Homo sapiens_hsa041400.50501643
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50182635
98Viral myocarditis_Homo sapiens_hsa054160.49724259
99PPAR signaling pathway_Homo sapiens_hsa033200.48760636
100African trypanosomiasis_Homo sapiens_hsa051430.46870130
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46790660
102Mineral absorption_Homo sapiens_hsa049780.46240734
103Pancreatic cancer_Homo sapiens_hsa052120.46176282
104Hepatitis B_Homo sapiens_hsa051610.46121035
105Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.46060367
106p53 signaling pathway_Homo sapiens_hsa041150.45788767
107Steroid biosynthesis_Homo sapiens_hsa001000.45379282
108Proteasome_Homo sapiens_hsa030500.43794729
109Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.43613123
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43251467
111Insulin resistance_Homo sapiens_hsa049310.42967159
112Collecting duct acid secretion_Homo sapiens_hsa049660.42336756
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.42294165
114Fatty acid elongation_Homo sapiens_hsa000620.42271220
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.41719376
116Epstein-Barr virus infection_Homo sapiens_hsa051690.39930408
117Fat digestion and absorption_Homo sapiens_hsa049750.39710037
118DNA replication_Homo sapiens_hsa030300.39504151
119Histidine metabolism_Homo sapiens_hsa003400.39259887
120Viral carcinogenesis_Homo sapiens_hsa052030.38847802
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38665341
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.38046422
123ABC transporters_Homo sapiens_hsa020100.37338465
124Homologous recombination_Homo sapiens_hsa034400.37190099
125Non-homologous end-joining_Homo sapiens_hsa034500.36578473
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.33877841
127Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32042610
128Neurotrophin signaling pathway_Homo sapiens_hsa047220.29488021

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