SCAMP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an integral membrane protein that belongs to the secretory carrier membrane protein family. The encoded protein functions as a carrier to the cell surface in post-golgi recycling pathways. This protein is also involved in protein trafficking in endosomal pathways. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.52551829
2protein maturation by protein folding (GO:0022417)5.35889719
3Golgi transport vesicle coating (GO:0048200)5.17883003
4COPI coating of Golgi vesicle (GO:0048205)5.17883003
5formation of translation preinitiation complex (GO:0001731)4.71491523
6proteasome assembly (GO:0043248)4.51850688
7L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.94774717
8negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.89383222
9ribosomal small subunit assembly (GO:0000028)3.85713649
10DNA strand elongation involved in DNA replication (GO:0006271)3.85479080
11viral transcription (GO:0019083)3.67691825
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.65451564
13ribosomal small subunit biogenesis (GO:0042274)3.64522815
14negative regulation of ligase activity (GO:0051352)3.63391793
15negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.63391793
16maturation of SSU-rRNA (GO:0030490)3.62135942
17DNA strand elongation (GO:0022616)3.62015961
18chaperone-mediated protein transport (GO:0072321)3.61456869
19regulation of mitochondrial translation (GO:0070129)3.61196899
20telomere maintenance via semi-conservative replication (GO:0032201)3.61067573
21negative regulation of B cell apoptotic process (GO:0002903)3.58816852
22translational termination (GO:0006415)3.56671947
23positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.56613991
24DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.50777457
25regulation of cellular amino acid metabolic process (GO:0006521)3.50103387
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.49076184
27anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.47851617
28antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.47756494
29amino acid salvage (GO:0043102)3.46464763
30L-methionine salvage (GO:0071267)3.46464763
31L-methionine biosynthetic process (GO:0071265)3.46464763
32translational elongation (GO:0006414)3.45835990
33signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.44554651
34intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.44554651
35signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.41863597
36signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.41863597
37signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.41863597
38translational initiation (GO:0006413)3.40138425
39nucleobase biosynthetic process (GO:0046112)3.39906263
40tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.39365489
41RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.39365489
42SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.37565408
43deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.36436447
44peptidyl-arginine omega-N-methylation (GO:0035247)3.35359205
45signal transduction involved in DNA integrity checkpoint (GO:0072401)3.34495382
46signal transduction involved in DNA damage checkpoint (GO:0072422)3.34495382
47folic acid metabolic process (GO:0046655)3.34126201
48antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.32585385
49antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.32585385
50mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.31700980
51guanosine-containing compound biosynthetic process (GO:1901070)3.31120000
52ribosome biogenesis (GO:0042254)3.30736657
53cotranslational protein targeting to membrane (GO:0006613)3.29856195
54pseudouridine synthesis (GO:0001522)3.27941639
55protein targeting to ER (GO:0045047)3.27322948
56signal transduction involved in cell cycle checkpoint (GO:0072395)3.26387735
57ribonucleoprotein complex biogenesis (GO:0022613)3.22582969
58mitotic nuclear envelope reassembly (GO:0007084)3.20909367
59nuclear envelope reassembly (GO:0031468)3.20909367
60protein localization to endoplasmic reticulum (GO:0070972)3.18387838
61ribosome assembly (GO:0042255)3.17240362
62translation (GO:0006412)3.13692109
63energy coupled proton transport, down electrochemical gradient (GO:0015985)3.13515522
64ATP synthesis coupled proton transport (GO:0015986)3.13515522
65Arp2/3 complex-mediated actin nucleation (GO:0034314)3.13196376
66DNA replication initiation (GO:0006270)3.13119321
67maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.13117432
68protein deneddylation (GO:0000338)3.12647559
69purine nucleobase biosynthetic process (GO:0009113)3.11777900
70regulation of cellular amine metabolic process (GO:0033238)3.11057449
71nucleotide salvage (GO:0043173)3.10785940
72protein localization to mitochondrion (GO:0070585)3.10499673
73NADH metabolic process (GO:0006734)3.08909388
74protein retention in ER lumen (GO:0006621)3.08002245
75establishment of protein localization to endoplasmic reticulum (GO:0072599)3.07950711
76positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.07364313
77oxidative phosphorylation (GO:0006119)3.07111993
78mannosylation (GO:0097502)3.06577662
79positive regulation of ligase activity (GO:0051351)3.04323313
80telomere maintenance via recombination (GO:0000722)3.03614898
81GTP biosynthetic process (GO:0006183)3.01686832
82purine nucleotide salvage (GO:0032261)3.00381415
83dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.99378980
84pentose metabolic process (GO:0019321)2.98117206
85base-excision repair, AP site formation (GO:0006285)2.97054670
86DNA replication checkpoint (GO:0000076)2.95773212
87regulation of protein heterodimerization activity (GO:0043497)2.95621911
88proline biosynthetic process (GO:0006561)2.95239412
89UTP biosynthetic process (GO:0006228)2.94721156
90retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.94073772
91positive regulation of cell cycle arrest (GO:0071158)2.92091988
92rRNA processing (GO:0006364)2.91990759
93viral life cycle (GO:0019058)2.91871022
94protein complex biogenesis (GO:0070271)2.91273204
95respiratory electron transport chain (GO:0022904)2.90565293
96GDP-mannose metabolic process (GO:0019673)2.89753563
97antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.89168204
98tRNA aminoacylation for protein translation (GO:0006418)2.87561917
99ribosomal large subunit biogenesis (GO:0042273)2.85545200
100nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.85393388
101folic acid-containing compound biosynthetic process (GO:0009396)2.85110655
102cullin deneddylation (GO:0010388)2.84237269
103electron transport chain (GO:0022900)2.83789097
104establishment of protein localization to mitochondrial membrane (GO:0090151)2.83111221
105pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.82140388
106negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.81558140
107pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.81311686
108tricarboxylic acid cycle (GO:0006099)2.79432730
109rRNA metabolic process (GO:0016072)2.79067314
110DNA unwinding involved in DNA replication (GO:0006268)2.78361636
111CTP metabolic process (GO:0046036)2.78025141
112CTP biosynthetic process (GO:0006241)2.78025141
113mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.77643901
114tRNA aminoacylation (GO:0043039)2.77526701
115amino acid activation (GO:0043038)2.77526701
116sequestering of actin monomers (GO:0042989)2.76879999
117cellular protein complex disassembly (GO:0043624)2.76735637
118heme metabolic process (GO:0042168)2.76506446
119regulation of ubiquitin-protein transferase activity (GO:0051438)2.76375693
120DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.75899887
121telomere maintenance via telomere lengthening (GO:0010833)2.75601839
122negative regulation of protein ubiquitination (GO:0031397)2.75492761
123spliceosomal snRNP assembly (GO:0000387)2.75320473
124regulation of ligase activity (GO:0051340)2.75255439
125pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.74308914
126heme biosynthetic process (GO:0006783)2.74169744
127termination of RNA polymerase III transcription (GO:0006386)2.73741261
128transcription elongation from RNA polymerase III promoter (GO:0006385)2.73741261
129mitochondrial respiratory chain complex assembly (GO:0033108)2.73234340
130peptidyl-histidine modification (GO:0018202)2.72925512
131cell cycle G1/S phase transition (GO:0044843)2.72572229
132G1/S transition of mitotic cell cycle (GO:0000082)2.72572229
133rRNA modification (GO:0000154)2.71191021
134nucleobase-containing small molecule interconversion (GO:0015949)2.70457288
135melanin biosynthetic process (GO:0042438)2.68350346
136negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.67784398
137NADH dehydrogenase complex assembly (GO:0010257)2.67662830
138mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.67662830
139methionine biosynthetic process (GO:0009086)2.67548635
140nucleoside salvage (GO:0043174)2.66632565
141cellular component biogenesis (GO:0044085)2.64380551
142iron-sulfur cluster assembly (GO:0016226)2.64025861
143metallo-sulfur cluster assembly (GO:0031163)2.64025861
144establishment of protein localization to mitochondrion (GO:0072655)2.61651518
145pentose-phosphate shunt (GO:0006098)2.60613089
146protein targeting to mitochondrion (GO:0006626)2.60551310
147nucleotide-excision repair, DNA gap filling (GO:0006297)2.59712656
148antigen processing and presentation of endogenous antigen (GO:0019883)2.59611792
149IMP biosynthetic process (GO:0006188)2.59175386
150negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.58199428
151regulation of cell cycle arrest (GO:0071156)2.57698243
152aspartate family amino acid biosynthetic process (GO:0009067)2.56424404
153folic acid transport (GO:0015884)2.55624654
154mitotic recombination (GO:0006312)2.54783523
155galactose catabolic process (GO:0019388)2.52556098

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.20593689
2E2F7_22180533_ChIP-Seq_HELA_Human3.94486330
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.50334994
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.13834233
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.05842392
6GABP_17652178_ChIP-ChIP_JURKAT_Human2.86070238
7* ETS1_20019798_ChIP-Seq_JURKAT_Human2.81091664
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71928997
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.70865783
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.70323053
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.37871723
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.31506172
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.29110581
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.26791463
15* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.16999943
16* XRN2_22483619_ChIP-Seq_HELA_Human2.11889858
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.10190419
18VDR_23849224_ChIP-Seq_CD4+_Human2.08689019
19MYC_22102868_ChIP-Seq_BL_Human1.97083315
20* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94695661
21GABP_19822575_ChIP-Seq_HepG2_Human1.91538383
22DCP1A_22483619_ChIP-Seq_HELA_Human1.90838491
23NELFA_20434984_ChIP-Seq_ESCs_Mouse1.89576929
24* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.88050982
25BP1_19119308_ChIP-ChIP_Hs578T_Human1.87935597
26* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.81340711
27FOXP3_21729870_ChIP-Seq_TREG_Human1.79679941
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.79471885
29ZNF263_19887448_ChIP-Seq_K562_Human1.78555686
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.77545699
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.77128391
32* SRF_21415370_ChIP-Seq_HL-1_Mouse1.68433829
33FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.66976976
34* VDR_21846776_ChIP-Seq_THP-1_Human1.66166142
35* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61911618
36E2F4_17652178_ChIP-ChIP_JURKAT_Human1.58423006
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53193454
38CIITA_25753668_ChIP-Seq_RAJI_Human1.51789955
39RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.51671831
40SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.49982447
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48204747
42* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46288246
43PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.43161339
44TTF2_22483619_ChIP-Seq_HELA_Human1.41995141
45NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.41310795
46TET1_21451524_ChIP-Seq_MESCs_Mouse1.39917520
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39186821
48RARG_19884340_ChIP-ChIP_MEFs_Mouse1.37931360
49MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.37600561
50LXR_22292898_ChIP-Seq_THP-1_Human1.36759339
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.35939358
52IRF8_22096565_ChIP-ChIP_GC-B_Human1.35783871
53HOXB4_20404135_ChIP-ChIP_EML_Mouse1.35190215
54SRY_22984422_ChIP-ChIP_TESTIS_Rat1.35039343
55SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.34922224
56* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.33373275
57FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33149947
58* SPI1_23547873_ChIP-Seq_NB4_Human1.31947490
59CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.31863719
60TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31675747
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.31210014
62* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.30953358
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.30511961
64ELF1_20517297_ChIP-Seq_JURKAT_Human1.29412368
65* TFEB_21752829_ChIP-Seq_HELA_Human1.28401935
66TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27029909
67* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.24808450
68POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24704340
69FOXM1_23109430_ChIP-Seq_U2OS_Human1.23408521
70CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.22986388
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22142560
72KDM5A_27292631_Chip-Seq_BREAST_Human1.21580480
73PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20417238
74P68_20966046_ChIP-Seq_HELA_Human1.20285517
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.19011880
76MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.18575667
77MAF_26560356_Chip-Seq_TH1_Human1.17032169
78BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16947050
79* TBX5_21415370_ChIP-Seq_HL-1_Mouse1.16245879
80SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.16095468
81EGR1_19374776_ChIP-ChIP_THP-1_Human1.16048877
82* UTX_26944678_Chip-Seq_JUKART_Human1.15796968
83CTCF_18555785_ChIP-Seq_MESCs_Mouse1.15770759
84* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14291105
85IRF8_21731497_ChIP-ChIP_J774_Mouse1.14240376
86ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.14116258
87* BCL6_27268052_Chip-Seq_Bcells_Human1.13971492
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13927616
89MYB_21317192_ChIP-Seq_ERMYB_Mouse1.13571093
90KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.13418027
91ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.13223816
92NOTCH1_21737748_ChIP-Seq_TLL_Human1.13174766
93IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.12426402
94* FOXP1_21924763_ChIP-Seq_HESCs_Human1.11988603
95ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.11730735
96TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11523315
97* RACK7_27058665_Chip-Seq_MCF-7_Human1.11437057
98* ELK3_25401928_ChIP-Seq_HUVEC_Human1.11293224
99HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.09646719
100CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.09581878
101MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09543256
102MAF_26560356_Chip-Seq_TH2_Human1.09253072
103STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09206171
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08760725
105GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07856871
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06143283
107SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.05382973
108CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05371812
109AR_21909140_ChIP-Seq_LNCAP_Human1.05105231
110E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04889790
111ELK1_22589737_ChIP-Seq_MCF10A_Human1.02928999
112RUNX1_22412390_ChIP-Seq_EML_Mouse1.02410103
113CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99605363
114CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99476516
115* SA1_27219007_Chip-Seq_ERYTHROID_Human0.99460988
116BCOR_27268052_Chip-Seq_Bcells_Human0.99031978
117* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.98295454
118ELK1_19687146_ChIP-ChIP_HELA_Human0.98045391
119MYB_26560356_Chip-Seq_TH2_Human0.97819666
120PU.1_20513432_ChIP-Seq_Bcells_Mouse0.95335064
121MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.95090808
122E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93595721
123FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93248561
124MYB_26560356_Chip-Seq_TH1_Human0.92988154

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.61945499
2MP0003806_abnormal_nucleotide_metabolis3.47980273
3MP0000372_irregular_coat_pigmentation3.36533422
4MP0005171_absent_coat_pigmentation3.24858856
5MP0004957_abnormal_blastocyst_morpholog3.00451088
6MP0003763_abnormal_thymus_physiology2.86073125
7MP0002877_abnormal_melanocyte_morpholog2.79839584
8MP0009840_abnormal_foam_cell2.70772600
9MP0009333_abnormal_splenocyte_physiolog2.69796235
10MP0002396_abnormal_hematopoietic_system2.65894943
11MP0003111_abnormal_nucleus_morphology2.42937912
12MP0005671_abnormal_response_to2.27399282
13MP0005408_hypopigmentation2.21909396
14MP0003077_abnormal_cell_cycle2.19143363
15MP0003186_abnormal_redox_activity2.11019447
16MP0010094_abnormal_chromosome_stability2.07269546
17MP0000685_abnormal_immune_system2.05227153
18MP0009785_altered_susceptibility_to1.94966744
19MP0005058_abnormal_lysosome_morphology1.94573131
20MP0000689_abnormal_spleen_morphology1.85886911
21MP0002398_abnormal_bone_marrow1.84954358
22MP0003436_decreased_susceptibility_to1.84855308
23MP0002722_abnormal_immune_system1.81746916
24MP0003656_abnormal_erythrocyte_physiolo1.80214313
25MP0000490_abnormal_crypts_of1.80059158
26MP0000858_altered_metastatic_potential1.79416742
27MP0003724_increased_susceptibility_to1.74168234
28MP0001545_abnormal_hematopoietic_system1.73747249
29MP0005397_hematopoietic_system_phenotyp1.73747249
30MP0001661_extended_life_span1.71934655
31MP0005025_abnormal_response_to1.66422644
32MP0001835_abnormal_antigen_presentation1.66414612
33MP0000015_abnormal_ear_pigmentation1.59415389
34MP0000751_myopathy1.59068004
35MP0001853_heart_inflammation1.58867653
36MP0002420_abnormal_adaptive_immunity1.57881745
37MP0000716_abnormal_immune_system1.57596864
38MP0001819_abnormal_immune_cell1.55692946
39MP0001800_abnormal_humoral_immune1.55615379
40MP0006036_abnormal_mitochondrial_physio1.54691230
41MP0008057_abnormal_DNA_replication1.54442125
42MP0002405_respiratory_system_inflammati1.54269840
43MP0002429_abnormal_blood_cell1.54210540
44MP0005000_abnormal_immune_tolerance1.54144751
45MP0005023_abnormal_wound_healing1.53946095
46MP0000604_amyloidosis1.53208990
47MP0002723_abnormal_immune_serum1.52068938
48MP0008932_abnormal_embryonic_tissue1.51852529
49MP0000703_abnormal_thymus_morphology1.51560138
50MP0008007_abnormal_cellular_replicative1.49163832
51MP0005464_abnormal_platelet_physiology1.48094535
52MP0002019_abnormal_tumor_incidence1.46900654
53MP0010352_gastrointestinal_tract_polyps1.43843061
54MP0008058_abnormal_DNA_repair1.43601355
55MP0006082_CNS_inflammation1.42386432
56MP0000358_abnormal_cell_content/1.41014986
57MP0003191_abnormal_cellular_cholesterol1.40745048
58MP0001730_embryonic_growth_arrest1.40111871
59MP0002452_abnormal_antigen_presenting1.38728498
60MP0003172_abnormal_lysosome_physiology1.38723499
61MP0004233_abnormal_muscle_weight1.38364356
62MP0008875_abnormal_xenobiotic_pharmacok1.36846088
63MP0005670_abnormal_white_adipose1.35492527
64MP0002132_abnormal_respiratory_system1.34208018
65MP0002419_abnormal_innate_immunity1.29794328
66MP0005451_abnormal_body_composition1.27036930
67MP0005075_abnormal_melanosome_morpholog1.26245125
68MP0004381_abnormal_hair_follicle1.24899508
69MP0003786_premature_aging1.23394052
70MP0005387_immune_system_phenotype1.21268347
71MP0001790_abnormal_immune_system1.21268347
72MP0000350_abnormal_cell_proliferation1.20726155
73MP0005083_abnormal_biliary_tract1.20521282
74MP0002933_joint_inflammation1.18907565
75MP0005165_increased_susceptibility_to1.16678125
76MP0006054_spinal_hemorrhage1.16623812
77MP0004808_abnormal_hematopoietic_stem1.14840047
78MP0008469_abnormal_protein_level1.14784841
79MP0001845_abnormal_inflammatory_respons1.14183462
80MP0002166_altered_tumor_susceptibility1.13790595
81MP0002139_abnormal_hepatobiliary_system1.13775465
82MP0005501_abnormal_skin_physiology1.12301699
83MP0000313_abnormal_cell_death1.11767404
84MP0004147_increased_porphyrin_level1.11577513
85MP0001533_abnormal_skeleton_physiology1.10799683
86MP0005584_abnormal_enzyme/coenzyme_acti1.09505723
87MP0001727_abnormal_embryo_implantation1.09018362
88MP0010155_abnormal_intestine_physiology1.08375235
89MP0003279_aneurysm1.05082319
90MP0003566_abnormal_cell_adhesion1.03316190
91MP0002080_prenatal_lethality1.03010867
92MP0003329_amyloid_beta_deposits1.02455853
93MP0001542_abnormal_bone_strength1.01313410
94MP0001764_abnormal_homeostasis1.00795117
95MP0005174_abnormal_tail_pigmentation1.00659449
96MP0000343_altered_response_to1.00424248
97MP0004858_abnormal_nervous_system1.00068018
98MP0000749_muscle_degeneration0.99810124
99MP0001905_abnormal_dopamine_level0.99459754
100MP0006035_abnormal_mitochondrial_morpho0.97324439
101MP0000598_abnormal_liver_morphology0.96998913
102MP0002269_muscular_atrophy0.96835344
103MP0005319_abnormal_enzyme/_coenzyme0.95723263
104MP0003221_abnormal_cardiomyocyte_apopto0.95384614
105MP0001881_abnormal_mammary_gland0.94322696
106MP0008438_abnormal_cutaneous_collagen0.91532823
107MP0001697_abnormal_embryo_size0.90833248
108MP0001873_stomach_inflammation0.90792997
109MP0008260_abnormal_autophagy0.90751943
110MP0003448_altered_tumor_morphology0.90308084
111MP0004947_skin_inflammation0.89898891
112MP0003075_altered_response_to0.89815235
113MP0000750_abnormal_muscle_regeneration0.88806347
114MP0002060_abnormal_skin_morphology0.88566587
115MP0009697_abnormal_copulation0.88551475
116MP0002148_abnormal_hypersensitivity_rea0.88403823
117MP0003866_abnormal_defecation0.88044085
118MP0009643_abnormal_urine_homeostasis0.87935901
119MP0005332_abnormal_amino_acid0.86744402
120MP0005330_cardiomyopathy0.85453968
121MP0001243_abnormal_dermal_layer0.85393427
122MP0002006_tumorigenesis0.84675484
123MP0005623_abnormal_meninges_morphology0.84386241
124MP0003136_yellow_coat_color0.84116213
125MP0005360_urolithiasis0.83232341
126MP0000681_abnormal_thyroid_gland0.82930997
127MP0000371_diluted_coat_color0.82844075
128MP0002089_abnormal_postnatal_growth/wei0.81517525
129MP0005266_abnormal_metabolism0.81265894
130MP0000465_gastrointestinal_hemorrhage0.79629366
131MP0000609_abnormal_liver_physiology0.79268233
132MP0000747_muscle_weakness0.76054295
133MP0000003_abnormal_adipose_tissue0.73759453
134MP0005257_abnormal_intraocular_pressure0.71530157
135MP0000678_abnormal_parathyroid_gland0.71469404
136MP0001529_abnormal_vocalization0.71274424
137MP0001186_pigmentation_phenotype0.69240197
138MP0002095_abnormal_skin_pigmentation0.69061356
139MP0000759_abnormal_skeletal_muscle0.67170951
140MP0005384_cellular_phenotype0.66330482
141MP0003718_maternal_effect0.65451924
142MP0000013_abnormal_adipose_tissue0.65223148

Predicted human phenotypes

RankGene SetZ-score
1Abnormal mitochondria in muscle tissue (HP:0008316)4.01317115
2Cholecystitis (HP:0001082)3.87353714
3Abnormal gallbladder physiology (HP:0012438)3.87353714
4Acute necrotizing encephalopathy (HP:0006965)3.73098950
5Abnormal number of erythroid precursors (HP:0012131)3.63000586
6Cerebral hypomyelination (HP:0006808)3.56914708
7Acute encephalopathy (HP:0006846)3.49914829
8Abnormality of cells of the erythroid lineage (HP:0012130)3.48213750
9Elevated erythrocyte sedimentation rate (HP:0003565)3.38443968
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.33596024
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.33596024
12Multiple enchondromatosis (HP:0005701)3.14626566
13Testicular atrophy (HP:0000029)3.12181827
14Petechiae (HP:0000967)3.11455249
15Microvesicular hepatic steatosis (HP:0001414)3.09275603
16Hepatic necrosis (HP:0002605)3.06679467
17Degeneration of anterior horn cells (HP:0002398)3.05419486
18Abnormality of the anterior horn cell (HP:0006802)3.05419486
19Hepatocellular necrosis (HP:0001404)3.03659397
20Oral leukoplakia (HP:0002745)3.01435745
21Exercise intolerance (HP:0003546)2.94635361
22Renal Fanconi syndrome (HP:0001994)2.94476648
23Spastic paraparesis (HP:0002313)2.85332057
24Combined immunodeficiency (HP:0005387)2.83861440
25Hypokinesia (HP:0002375)2.82456475
26Increased hepatocellular lipid droplets (HP:0006565)2.79495360
27IgM deficiency (HP:0002850)2.78976590
28Progressive macrocephaly (HP:0004481)2.76144285
29Lipid accumulation in hepatocytes (HP:0006561)2.67952056
30Rough bone trabeculation (HP:0100670)2.67309902
31Trismus (HP:0000211)2.66117161
32Aplastic anemia (HP:0001915)2.63857727
33Type I transferrin isoform profile (HP:0003642)2.62320628
34Severe combined immunodeficiency (HP:0004430)2.60113978
35T lymphocytopenia (HP:0005403)2.57553616
36Thrombocytosis (HP:0001894)2.54856517
37Cerebral edema (HP:0002181)2.54815658
38Atrophy/Degeneration involving motor neurons (HP:0007373)2.54434788
39Increased serum lactate (HP:0002151)2.52366045
40Increased serum ferritin (HP:0003281)2.49295657
41Reticulocytopenia (HP:0001896)2.48800010
42Vertebral compression fractures (HP:0002953)2.48529961
43Poor head control (HP:0002421)2.45374511
44Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.45001243
45Pustule (HP:0200039)2.43041599
46Abnormality of T cell number (HP:0011839)2.41932631
47Respiratory failure (HP:0002878)2.40803892
48Cholelithiasis (HP:0001081)2.39876527
49Reduced antithrombin III activity (HP:0001976)2.38960984
50Neoplasm of head and neck (HP:0012288)2.38101097
51Esophageal neoplasm (HP:0100751)2.38101097
52Microretrognathia (HP:0000308)2.34686047
53Upper limb muscle weakness (HP:0003484)2.32285222
54Abnormality of T cells (HP:0002843)2.27657750
55Decreased electroretinogram (ERG) amplitude (HP:0000654)2.25991910
56Abnormal gallbladder morphology (HP:0012437)2.25482572
57Birth length less than 3rd percentile (HP:0003561)2.24673150
58Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.24122437
59Breast hypoplasia (HP:0003187)2.23537747
60Recurrent bronchitis (HP:0002837)2.23165794
61Vacuolated lymphocytes (HP:0001922)2.22671822
62Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.22313888
63Abnormal protein N-linked glycosylation (HP:0012347)2.22313888
64Abnormal protein glycosylation (HP:0012346)2.22313888
65Abnormal glycosylation (HP:0012345)2.22313888
66Abnormality of the umbilical cord (HP:0010881)2.21315235
67Macrocytic anemia (HP:0001972)2.21293808
68Carpal bone hypoplasia (HP:0001498)2.19408285
69Chronic otitis media (HP:0000389)2.19359438
70CNS demyelination (HP:0007305)2.18606450
71Rhabdomyolysis (HP:0003201)2.18143832
72Mitochondrial inheritance (HP:0001427)2.18076237
73Prolonged neonatal jaundice (HP:0006579)2.17713199
74Patchy hypopigmentation of hair (HP:0011365)2.15884993
75Entropion (HP:0000621)2.15726954
76Beaking of vertebral bodies (HP:0004568)2.15256273
77Emotional lability (HP:0000712)2.14931384
78Premature ovarian failure (HP:0008209)2.14697157
79Abnormality of aromatic amino acid family metabolism (HP:0004338)2.14496247
80Purpura (HP:0000979)2.13913954
81Increased muscle lipid content (HP:0009058)2.13365077
82Muscle fiber atrophy (HP:0100295)2.11657163
83Nasal polyposis (HP:0100582)2.11581980
84Nonimmune hydrops fetalis (HP:0001790)2.11024709
85Increased intramyocellular lipid droplets (HP:0012240)2.08317338
86Abnormal umbilical cord blood vessels (HP:0011403)2.08294102
87Single umbilical artery (HP:0001195)2.08294102
88Abnormality of the fetal cardiovascular system (HP:0010948)2.08294102
89Increased serum pyruvate (HP:0003542)2.08226110
90Abnormality of glycolysis (HP:0004366)2.08226110
91Abnormal neuron morphology (HP:0012757)2.06990064
92Abnormality of the motor neurons (HP:0002450)2.06990064
93Opisthotonus (HP:0002179)2.06871749
94Lactic acidosis (HP:0003128)2.05033406
95Abnormal trabecular bone morphology (HP:0100671)2.04724276
96Cutaneous melanoma (HP:0012056)2.04057526
97Increased CSF lactate (HP:0002490)2.03815553
98Hepatosplenomegaly (HP:0001433)2.03331177
993-Methylglutaconic aciduria (HP:0003535)2.02528124
100Exertional dyspnea (HP:0002875)2.01903147
101Abnormality of iron homeostasis (HP:0011031)2.01700356
102Recurrent abscess formation (HP:0002722)2.01638043
103Nausea (HP:0002018)2.01300151
104Hypoplasia of the thymus (HP:0000778)2.00981592
105IgG deficiency (HP:0004315)2.00911124
106Selective tooth agenesis (HP:0001592)1.99671011
107Sparse eyelashes (HP:0000653)1.96483256
108White forelock (HP:0002211)1.95738943
109Secondary amenorrhea (HP:0000869)1.95512733
110Hand muscle atrophy (HP:0009130)1.95503920
111Progressive muscle weakness (HP:0003323)1.94683683
112Hypertensive crisis (HP:0100735)1.94488980
113Abnormality of the gallbladder (HP:0005264)1.94249182
114Respiratory difficulties (HP:0002880)1.94169195
115Pancytopenia (HP:0001876)1.93831073
116Aplasia/Hypoplasia of the sacrum (HP:0008517)1.93549292
117Biconcave vertebral bodies (HP:0004586)1.93489921
118Abnormality of dicarboxylic acid metabolism (HP:0010995)1.92725743
119Dicarboxylic aciduria (HP:0003215)1.92725743
120J-shaped sella turcica (HP:0002680)1.92159697
121Abnormalities of placenta or umbilical cord (HP:0001194)1.91884838
122Protrusio acetabuli (HP:0003179)1.91792648
123Abnormality of fatty-acid metabolism (HP:0004359)1.91700557
124Pallor (HP:0000980)1.91686963
125Distal lower limb muscle weakness (HP:0009053)1.90599600
126Abnormality of the nasal mucosa (HP:0000433)1.90592707
127Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89824116
128Abnormality of alanine metabolism (HP:0010916)1.89824116
129Hyperalaninemia (HP:0003348)1.89824116
130Methylmalonic aciduria (HP:0012120)1.89731529
131Delusions (HP:0000746)1.89280367
132CNS hypomyelination (HP:0003429)1.88688136
133Progressive neurologic deterioration (HP:0002344)1.86615652
134Paraparesis (HP:0002385)1.85034422
135Abnormality of eosinophils (HP:0001879)1.85003671
136Upper limb amyotrophy (HP:0009129)1.84916226
137Distal upper limb amyotrophy (HP:0007149)1.84916226
138Lethargy (HP:0001254)1.84391529
139Abnormality of T cell physiology (HP:0011840)1.84222962
140Ragged-red muscle fibers (HP:0003200)1.84103600
141Fasciculations (HP:0002380)1.83450728
142Muscle fibrillation (HP:0010546)1.83047083
143Tongue fasciculations (HP:0001308)1.82376116
144Type 2 muscle fiber atrophy (HP:0003554)1.82330755
145Premature graying of hair (HP:0002216)1.81948098
146Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.81051137
147Generalized aminoaciduria (HP:0002909)1.80707468
148Abnormality of liposaccharide metabolism (HP:0010968)1.80679786
149Abnormality of glycosphingolipid metabolism (HP:0004343)1.80679786
150Abnormality of glycolipid metabolism (HP:0010969)1.80679786
151Dysostosis multiplex (HP:0000943)1.80656904
152Lymphopenia (HP:0001888)1.79558644
153Lymphoma (HP:0002665)1.78130327
154Personality changes (HP:0000751)1.77818827

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.86005368
2VRK23.76057859
3KDR3.66229553
4NME23.42214303
5TESK23.40647174
6STK163.05295816
7MAP4K12.95866486
8PIM22.80027782
9EIF2AK12.60825814
10ERN12.50578228
11WEE12.37308087
12ZAP702.21493363
13BCKDK2.18936777
14MAP3K111.95278326
15EIF2AK31.88742609
16TESK11.79727252
17TXK1.78185784
18PDK21.70255597
19CDC71.65187104
20SCYL21.63326132
21MAPKAPK31.56579663
22PBK1.53502865
23LRRK21.50842300
24BLK1.42940964
25STK101.42577775
26ARAF1.41809304
27RPS6KA41.41216815
28ACVR1B1.35024355
29LIMK11.32513097
30TYK21.32088340
31SRPK11.29419469
32TSSK61.28051776
33TRIB31.25104211
34TBK11.24288880
35JAK31.16090995
36LMTK21.16048887
37SMG11.13718505
38PAK41.11532020
39EPHA21.08907560
40VRK11.07906735
41TRIM281.06660299
42RPS6KB21.06656867
43CDK71.06058068
44CSNK1A1L1.05918035
45BTK1.04570308
46NEK11.03306046
47MAP2K30.97977048
48GRK60.97254802
49MAP3K120.94692175
50IKBKE0.92340313
51FGFR40.90968774
52NEK20.90388468
53PKN20.88923557
54MAP3K80.88878713
55IRAK40.88278814
56AURKA0.87686176
57MST1R0.86803718
58PIM10.86130762
59ILK0.85290652
60CSNK1G10.83803978
61CCNB10.83230363
62SIK10.83167171
63KIT0.82919125
64TIE10.82883515
65EEF2K0.82777764
66MYLK0.80992816
67DAPK10.80691769
68CDK40.80559753
69DAPK30.80472438
70ABL20.80344270
71PLK10.79665237
72ITK0.79056422
73CSNK1G20.74993829
74PAK10.74251268
75BRSK20.73399506
76DYRK30.72348236
77CDK80.72089408
78ICK0.71404567
79TGFBR10.68193086
80FLT30.68116576
81TAOK20.67256490
82NLK0.67226153
83LCK0.66998274
84TAOK10.66478231
85MST40.66202128
86TEC0.66195298
87CDK190.65821960
88AURKB0.65566705
89PLK40.65404782
90SYK0.64537423
91IRAK30.63612465
92SIK30.63175520
93NME10.61695138
94TLK10.60331916
95PTK20.56294738
96BRAF0.55854351
97MARK30.54137037
98GRK70.53610108
99ATR0.53175431
100MAP3K30.52710432
101PHKG10.52503945
102PHKG20.52503945
103MAP3K50.50759680
104LYN0.49429829
105CSNK2A20.49382256
106MAP4K20.49152096
107TTK0.48715576
108RAF10.48286951
109MAPK110.46781907
110IKBKB0.46619726
111CAMK2G0.46322368
112BRSK10.46061447
113CSNK2A10.45225600
114MAPKAPK50.44632726
115PRKCI0.44520238
116MAP3K100.44416099
117PASK0.41771572
118ERBB40.41642262
119AKT20.40301158
120GRK50.39195970
121IRAK20.38383379
122MUSK0.38067108
123PRKD20.38043251
124PRKD30.37807986
125MAPKAPK20.37493459
126CHEK20.37294458
127CAMK2D0.36924274
128CDK140.34591552
129CSK0.33916382
130CLK10.33554734
131CSNK1G30.32700937
132PRKCD0.31969366
133RPS6KA60.31579582
134PIK3CG0.31168395
135RPS6KA50.30769416
136DYRK20.30585298
137NUAK10.29876105
138PRKD10.29851349
139CDK90.28796424

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.48870510
2DNA replication_Homo sapiens_hsa030303.82493161
3Ribosome_Homo sapiens_hsa030103.68012763
4RNA polymerase_Homo sapiens_hsa030202.94394407
5Mismatch repair_Homo sapiens_hsa034302.81530919
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.52685751
7Pyrimidine metabolism_Homo sapiens_hsa002402.32882810
8Base excision repair_Homo sapiens_hsa034102.28255191
9Spliceosome_Homo sapiens_hsa030402.27198100
10Nucleotide excision repair_Homo sapiens_hsa034202.12484683
11RNA transport_Homo sapiens_hsa030131.94659805
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89706591
13Pentose phosphate pathway_Homo sapiens_hsa000301.86856031
14Sulfur relay system_Homo sapiens_hsa041221.79228492
15Primary immunodeficiency_Homo sapiens_hsa053401.73813024
16Folate biosynthesis_Homo sapiens_hsa007901.70159262
17Homologous recombination_Homo sapiens_hsa034401.60400500
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.57651877
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.55129230
20Vibrio cholerae infection_Homo sapiens_hsa051101.52127214
21Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.49227786
22One carbon pool by folate_Homo sapiens_hsa006701.48720137
23Protein export_Homo sapiens_hsa030601.47009937
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.46384505
25Other glycan degradation_Homo sapiens_hsa005111.38947944
26Cell cycle_Homo sapiens_hsa041101.37469072
27Sulfur metabolism_Homo sapiens_hsa009201.34526846
28Antigen processing and presentation_Homo sapiens_hsa046121.29469496
29Biosynthesis of amino acids_Homo sapiens_hsa012301.29144994
30Carbon metabolism_Homo sapiens_hsa012001.25821470
31p53 signaling pathway_Homo sapiens_hsa041151.24381938
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.20906689
33Parkinsons disease_Homo sapiens_hsa050121.20278133
34Drug metabolism - other enzymes_Homo sapiens_hsa009831.17675124
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.16332013
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.13956496
37Oxidative phosphorylation_Homo sapiens_hsa001901.13405702
38Collecting duct acid secretion_Homo sapiens_hsa049661.11565329
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04646149
40Epstein-Barr virus infection_Homo sapiens_hsa051691.03535314
41Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.03459110
42Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00387661
43Glutathione metabolism_Homo sapiens_hsa004800.96304353
44Purine metabolism_Homo sapiens_hsa002300.95703550
45Shigellosis_Homo sapiens_hsa051310.92096982
46Basal transcription factors_Homo sapiens_hsa030220.90029901
47Galactose metabolism_Homo sapiens_hsa000520.89781353
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.88544489
49Lysosome_Homo sapiens_hsa041420.88322577
50RNA degradation_Homo sapiens_hsa030180.87175208
51Huntingtons disease_Homo sapiens_hsa050160.84499421
52Non-homologous end-joining_Homo sapiens_hsa034500.83613406
53Fructose and mannose metabolism_Homo sapiens_hsa000510.83469801
54Phenylalanine metabolism_Homo sapiens_hsa003600.80520722
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80503020
56Measles_Homo sapiens_hsa051620.80419961
57Regulation of autophagy_Homo sapiens_hsa041400.78829607
58Hematopoietic cell lineage_Homo sapiens_hsa046400.78661373
59Rheumatoid arthritis_Homo sapiens_hsa053230.78433822
60Vitamin B6 metabolism_Homo sapiens_hsa007500.78411737
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73989205
62Legionellosis_Homo sapiens_hsa051340.72881685
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.72261747
64Allograft rejection_Homo sapiens_hsa053300.70687931
65Caffeine metabolism_Homo sapiens_hsa002320.70034228
66N-Glycan biosynthesis_Homo sapiens_hsa005100.68769991
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66954617
68Autoimmune thyroid disease_Homo sapiens_hsa053200.65062527
69Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64086086
70Leishmaniasis_Homo sapiens_hsa051400.64037486
71Herpes simplex infection_Homo sapiens_hsa051680.64021365
72Asthma_Homo sapiens_hsa053100.62225328
73Selenocompound metabolism_Homo sapiens_hsa004500.61331436
74Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60490890
75Fatty acid metabolism_Homo sapiens_hsa012120.60364158
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.60094014
77Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57794414
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57626639
79Pyruvate metabolism_Homo sapiens_hsa006200.57268301
80Apoptosis_Homo sapiens_hsa042100.56488665
81Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56400454
82Metabolic pathways_Homo sapiens_hsa011000.54949436
83Thyroid cancer_Homo sapiens_hsa052160.54727202
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53768444
85Viral myocarditis_Homo sapiens_hsa054160.53585728
86Steroid biosynthesis_Homo sapiens_hsa001000.53423731
87Arginine and proline metabolism_Homo sapiens_hsa003300.53159169
88Renin-angiotensin system_Homo sapiens_hsa046140.53111243
89Fatty acid elongation_Homo sapiens_hsa000620.52543020
90Graft-versus-host disease_Homo sapiens_hsa053320.50946684
91Type I diabetes mellitus_Homo sapiens_hsa049400.49668949
92Tyrosine metabolism_Homo sapiens_hsa003500.49644090
93Cardiac muscle contraction_Homo sapiens_hsa042600.49511985
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47746799
95Peroxisome_Homo sapiens_hsa041460.46401047
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45143872
97Alzheimers disease_Homo sapiens_hsa050100.44633395
98HTLV-I infection_Homo sapiens_hsa051660.44043466
99Fanconi anemia pathway_Homo sapiens_hsa034600.43616108
100Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43272943
101Propanoate metabolism_Homo sapiens_hsa006400.41835785
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41241244
103Salmonella infection_Homo sapiens_hsa051320.40260729
104Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.40065931
105Viral carcinogenesis_Homo sapiens_hsa052030.38121056
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37712807
107mRNA surveillance pathway_Homo sapiens_hsa030150.37621137
108Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37375539
109T cell receptor signaling pathway_Homo sapiens_hsa046600.36787476
110RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.36091900
111Intestinal immune network for IgA production_Homo sapiens_hsa046720.34806206
112Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.34076759
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.33849810
114Synaptic vesicle cycle_Homo sapiens_hsa047210.32498584
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32030957
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.31450024
117Staphylococcus aureus infection_Homo sapiens_hsa051500.28886188
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.28443656
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.27839597
120Hepatitis B_Homo sapiens_hsa051610.26334643
121Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.25677644
122Sphingolipid metabolism_Homo sapiens_hsa006000.24548968

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