SCAPER

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.11250382
2pyrimidine nucleobase catabolic process (GO:0006208)4.03868740
3startle response (GO:0001964)3.95049220
4protein localization to cilium (GO:0061512)3.91851366
5negative regulation of cytosolic calcium ion concentration (GO:0051481)3.82949164
6regulation of short-term neuronal synaptic plasticity (GO:0048172)3.66469846
7innervation (GO:0060384)3.65571705
8behavioral response to nicotine (GO:0035095)3.65473121
9auditory behavior (GO:0031223)3.62679975
10ionotropic glutamate receptor signaling pathway (GO:0035235)3.58733413
11nucleobase catabolic process (GO:0046113)3.56556012
12behavioral response to ethanol (GO:0048149)3.53714743
13vocalization behavior (GO:0071625)3.49875097
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.49399624
15cilium or flagellum-dependent cell motility (GO:0001539)3.44507818
16piRNA metabolic process (GO:0034587)3.41847087
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.38238349
18nonmotile primary cilium assembly (GO:0035058)3.35041085
19glutamate receptor signaling pathway (GO:0007215)3.35005268
20gamma-aminobutyric acid transport (GO:0015812)3.31183509
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.29716813
22regulation of glutamate receptor signaling pathway (GO:1900449)3.28647865
23regulation of synaptic vesicle exocytosis (GO:2000300)3.28565770
24neurotransmitter-gated ion channel clustering (GO:0072578)3.23589452
25regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21558955
26regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.21359550
27postsynaptic membrane organization (GO:0001941)3.18522197
28mechanosensory behavior (GO:0007638)3.18501570
29cerebellar Purkinje cell differentiation (GO:0021702)3.18449537
30retinal cone cell development (GO:0046549)3.17037669
31neuron recognition (GO:0008038)3.15838454
32response to pheromone (GO:0019236)3.13544074
33protein localization to synapse (GO:0035418)3.13368503
34proline transport (GO:0015824)3.13274706
35layer formation in cerebral cortex (GO:0021819)3.12839617
36response to auditory stimulus (GO:0010996)3.12476117
37presynaptic membrane assembly (GO:0097105)3.10149820
38regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.04954164
39male meiosis (GO:0007140)3.02480419
40DNA methylation involved in gamete generation (GO:0043046)3.01764826
41cochlea development (GO:0090102)3.01649660
42intraciliary transport (GO:0042073)2.99867843
43neuronal action potential (GO:0019228)2.99247503
44synaptic vesicle exocytosis (GO:0016079)2.96589677
45central nervous system projection neuron axonogenesis (GO:0021952)2.94813778
46synaptic transmission, glutamatergic (GO:0035249)2.94098181
47axonal fasciculation (GO:0007413)2.92486381
48glycosphingolipid biosynthetic process (GO:0006688)2.92020142
49cilium movement (GO:0003341)2.91713132
50epithelial cilium movement (GO:0003351)2.91362654
51regulation of synaptic vesicle transport (GO:1902803)2.89425111
52locomotory exploration behavior (GO:0035641)2.89095675
53dendritic spine morphogenesis (GO:0060997)2.88587132
54transmission of nerve impulse (GO:0019226)2.86095000
55acrosome assembly (GO:0001675)2.84586092
56detection of light stimulus involved in visual perception (GO:0050908)2.82552063
57detection of light stimulus involved in sensory perception (GO:0050962)2.82552063
58positive regulation of meiosis (GO:0045836)2.82157067
59retrograde transport, vesicle recycling within Golgi (GO:0000301)2.80861070
60detection of calcium ion (GO:0005513)2.80574683
61cilium organization (GO:0044782)2.79935511
62regulation of action potential (GO:0098900)2.79018097
63epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.78710217
64retinal ganglion cell axon guidance (GO:0031290)2.76324440
65cilium morphogenesis (GO:0060271)2.75870151
66synapse assembly (GO:0007416)2.75726785
67negative regulation of synaptic transmission, GABAergic (GO:0032229)2.73485863
68exploration behavior (GO:0035640)2.72987044
69protein polyglutamylation (GO:0018095)2.71731807
70neural tube formation (GO:0001841)2.69950525
71limb bud formation (GO:0060174)2.68654550
72membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.67718525
73neuron-neuron synaptic transmission (GO:0007270)2.66447687
74axoneme assembly (GO:0035082)2.64896593
75vesicle transport along microtubule (GO:0047496)2.64588619
76positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.63947813
77neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.63040912
78ventricular system development (GO:0021591)2.62823511
79regulation of vesicle fusion (GO:0031338)2.61277676
80presynaptic membrane organization (GO:0097090)2.60467488
81dendrite morphogenesis (GO:0048813)2.59938756
82regulation of synaptic transmission, glutamatergic (GO:0051966)2.58267734
83urinary tract smooth muscle contraction (GO:0014848)2.58131474
84positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.56720217
85gamma-aminobutyric acid signaling pathway (GO:0007214)2.56430170
86regulation of cAMP-dependent protein kinase activity (GO:2000479)2.56136581
87synaptic vesicle endocytosis (GO:0048488)2.54300444
88histone H3-K4 trimethylation (GO:0080182)2.54000531
89protein targeting to Golgi (GO:0000042)2.53929182
90regulation of respiratory system process (GO:0044065)2.53828622
91centriole replication (GO:0007099)2.53427913
92inner ear receptor cell development (GO:0060119)2.51675863
93brain morphogenesis (GO:0048854)2.51335647
94long-term memory (GO:0007616)2.51192459
95positive regulation of meiotic cell cycle (GO:0051446)2.50562135
96inner ear receptor stereocilium organization (GO:0060122)2.50350767
97striatum development (GO:0021756)2.50296807
98regulation of long-term neuronal synaptic plasticity (GO:0048169)2.49960769
99synaptic vesicle maturation (GO:0016188)2.49826226
100protein localization to Golgi apparatus (GO:0034067)2.49388881
101G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.48563084
102cellular ketone body metabolic process (GO:0046950)2.48448143
103regulation of neuronal synaptic plasticity (GO:0048168)2.47956301
104retinal rod cell development (GO:0046548)2.47795228
105glutamate secretion (GO:0014047)2.47767030
106calcium ion-dependent exocytosis (GO:0017156)2.47674708
107central nervous system neuron axonogenesis (GO:0021955)2.47128129
108neurotransmitter secretion (GO:0007269)2.47012889
109negative regulation of dendrite development (GO:2000171)2.46329617
110regulation of cilium movement (GO:0003352)2.46074993
111photoreceptor cell development (GO:0042461)2.45528493
112glycerophospholipid catabolic process (GO:0046475)2.44675600
113negative regulation of translation, ncRNA-mediated (GO:0040033)2.44581336
114regulation of translation, ncRNA-mediated (GO:0045974)2.44581336
115negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.44581336
116regulation of neurotransmitter secretion (GO:0046928)2.44557955
117retina layer formation (GO:0010842)2.44464247
118membrane depolarization during action potential (GO:0086010)2.44314241
119regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.43439209
120regulation of meiosis I (GO:0060631)2.43126967
121microtubule anchoring (GO:0034453)2.42302454
122sperm motility (GO:0030317)2.42154575
123regulation of hexokinase activity (GO:1903299)2.41976594
124regulation of glucokinase activity (GO:0033131)2.41976594
125C4-dicarboxylate transport (GO:0015740)2.41953330
126positive regulation of action potential (GO:0045760)2.41585772
127negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.41335262
128regulation of postsynaptic membrane potential (GO:0060078)2.41118689
129sympathetic nervous system development (GO:0048485)2.40908500
130neuronal action potential propagation (GO:0019227)2.40813722
131establishment of protein localization to Golgi (GO:0072600)2.40314519
132synaptic vesicle docking involved in exocytosis (GO:0016081)2.39711433
133long-term synaptic potentiation (GO:0060291)2.39270516
134positive regulation of synapse assembly (GO:0051965)2.38757342
135inositol phosphate catabolic process (GO:0071545)2.38245364
136detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.37570151
137regulation of excitatory postsynaptic membrane potential (GO:0060079)2.36253672
138regulation of respiratory gaseous exchange (GO:0043576)2.36171754
139protein K11-linked deubiquitination (GO:0035871)2.35758191
140negative regulation of neurotransmitter transport (GO:0051589)2.35688618
141cellular component assembly involved in morphogenesis (GO:0010927)2.35218173
142positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.34550761
143cilium assembly (GO:0042384)2.34200607
144regulation of protein polyubiquitination (GO:1902914)2.33196965
145regulation of synaptic transmission, GABAergic (GO:0032228)2.32407448
146cerebral cortex radially oriented cell migration (GO:0021799)2.31475090
147synapse organization (GO:0050808)2.31081138
148photoreceptor cell differentiation (GO:0046530)2.30556349
149eye photoreceptor cell differentiation (GO:0001754)2.30556349
150regulation of calcium ion-dependent exocytosis (GO:0017158)2.29885162

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.39483799
2GBX2_23144817_ChIP-Seq_PC3_Human3.58390418
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.55730131
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.38212650
5* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30611233
6IGF1R_20145208_ChIP-Seq_DFB_Human2.27539505
7TAF15_26573619_Chip-Seq_HEK293_Human2.13481883
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.06866948
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.06075541
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.04309502
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.04215826
12* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.01406383
13* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.99835335
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95565770
15SMAD4_21799915_ChIP-Seq_A2780_Human1.94766080
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.93115281
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.90217022
18PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86549169
19P300_19829295_ChIP-Seq_ESCs_Human1.85083260
20REST_21632747_ChIP-Seq_MESCs_Mouse1.83813495
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.82026984
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80453051
23EZH2_27304074_Chip-Seq_ESCs_Mouse1.80216042
24SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.75876020
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.72888862
26CDX2_19796622_ChIP-Seq_MESCs_Mouse1.71990488
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70663506
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.70357004
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.68641255
30* FUS_26573619_Chip-Seq_HEK293_Human1.67356338
31SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.67208426
32* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.66527472
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.66443242
34RNF2_27304074_Chip-Seq_NSC_Mouse1.62487724
35SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.61034524
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.60867249
37EZH2_18974828_ChIP-Seq_MESCs_Mouse1.60535822
38RNF2_18974828_ChIP-Seq_MESCs_Mouse1.60535822
39SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.60012827
40MTF2_20144788_ChIP-Seq_MESCs_Mouse1.59157745
41RNF2_27304074_Chip-Seq_ESCs_Mouse1.58335368
42* STAT3_23295773_ChIP-Seq_U87_Human1.56559452
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.56086490
44CBP_20019798_ChIP-Seq_JUKART_Human1.56086490
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.55336198
46JARID2_20075857_ChIP-Seq_MESCs_Mouse1.54769306
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.54478159
48TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.51518522
49NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51465138
50CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50927041
51FLI1_27457419_Chip-Seq_LIVER_Mouse1.50765082
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.48802541
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.46938507
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44417626
55NANOG_18555785_Chip-Seq_ESCs_Mouse1.43488603
56ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43010754
57DROSHA_22980978_ChIP-Seq_HELA_Human1.42552206
58ZNF274_21170338_ChIP-Seq_K562_Hela1.42517178
59EZH2_27294783_Chip-Seq_ESCs_Mouse1.42364448
60* AR_25329375_ChIP-Seq_VCAP_Human1.42277359
61AR_21572438_ChIP-Seq_LNCaP_Human1.41936700
62MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.41790718
63* TCF4_23295773_ChIP-Seq_U87_Human1.41779466
64AHR_22903824_ChIP-Seq_MCF-7_Human1.41574555
65SUZ12_27294783_Chip-Seq_ESCs_Mouse1.39523338
66ARNT_22903824_ChIP-Seq_MCF-7_Human1.38765568
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38452387
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38452387
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36923104
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34711322
71RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33631487
72SOX2_21211035_ChIP-Seq_LN229_Gbm1.32784887
73EWS_26573619_Chip-Seq_HEK293_Human1.30162511
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29883065
75E2F1_18555785_Chip-Seq_ESCs_Mouse1.29796627
76ER_23166858_ChIP-Seq_MCF-7_Human1.28510459
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.28122129
78* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27728897
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27046609
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26997699
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.26416834
82TCF4_22108803_ChIP-Seq_LS180_Human1.25226648
83RBPJ_22232070_ChIP-Seq_NCS_Mouse1.24999300
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.23955323
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.23657459
86NR3C1_21868756_ChIP-Seq_MCF10A_Human1.23152000
87TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23073275
88EZH2_27294783_Chip-Seq_NPCs_Mouse1.22624091
89CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21903119
90TP53_22573176_ChIP-Seq_HFKS_Human1.20231459
91TAL1_26923725_Chip-Seq_HPCs_Mouse1.19938852
92RUNX2_22187159_ChIP-Seq_PCA_Human1.19878652
93REST_18959480_ChIP-ChIP_MESCs_Mouse1.17755841
94FLI1_21867929_ChIP-Seq_TH2_Mouse1.17580589
95MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17095606
96* BCAT_22108803_ChIP-Seq_LS180_Human1.17089551
97CMYC_18555785_Chip-Seq_ESCs_Mouse1.16591197
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16015420
99PCGF2_27294783_Chip-Seq_NPCs_Mouse1.15437934
100PRDM14_20953172_ChIP-Seq_ESCs_Human1.15060379
101P53_22387025_ChIP-Seq_ESCs_Mouse1.14852885
102YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14012725
103NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12974742
104AR_19668381_ChIP-Seq_PC3_Human1.12002730
105KDM2B_26808549_Chip-Seq_REH_Human1.11814331
106NANOG_19829295_ChIP-Seq_ESCs_Human1.11698428
107SOX2_19829295_ChIP-Seq_ESCs_Human1.11698428
108TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11681026
109VDR_22108803_ChIP-Seq_LS180_Human1.11485473
110RARB_27405468_Chip-Seq_BRAIN_Mouse1.11283342
111SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10972746
112PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09656296
113CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08599258
114CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07369943
115NFE2_27457419_Chip-Seq_LIVER_Mouse1.07255719
116TCF4_18268006_ChIP-ChIP_LS174T_Human1.06839955
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06671663
118MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05989481
119LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05848547
120SMAD3_21741376_ChIP-Seq_ESCs_Human1.05323275
121* SMAD4_21741376_ChIP-Seq_EPCs_Human1.05237726
122EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03462329
123KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.02022872
124RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01290278
125TP53_16413492_ChIP-PET_HCT116_Human0.99981219
126HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.99969925
127JUN_21703547_ChIP-Seq_K562_Human0.99338467
128TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99337239
129STAT3_18555785_Chip-Seq_ESCs_Mouse0.97710723

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.35215172
2MP0004859_abnormal_synaptic_plasticity3.31468207
3MP0003787_abnormal_imprinting3.20277032
4MP0000569_abnormal_digit_pigmentation3.15677805
5MP0008877_abnormal_DNA_methylation2.96748622
6MP0003635_abnormal_synaptic_transmissio2.86216795
7MP0004270_analgesia2.69788867
8MP0001968_abnormal_touch/_nociception2.64829093
9MP0005423_abnormal_somatic_nervous2.55184595
10MP0002063_abnormal_learning/memory/cond2.50635618
11MP0001188_hyperpigmentation2.48161451
12MP0002572_abnormal_emotion/affect_behav2.42464988
13MP0002837_dystrophic_cardiac_calcinosis2.36491542
14MP0009745_abnormal_behavioral_response2.29207611
15MP0002734_abnormal_mechanical_nocicepti2.24660198
16MP0000778_abnormal_nervous_system2.20491407
17MP0001501_abnormal_sleep_pattern2.16070168
18MP0006276_abnormal_autonomic_nervous2.15403351
19MP0002735_abnormal_chemical_nociception2.15234537
20MP0001486_abnormal_startle_reflex2.15133935
21MP0001502_abnormal_circadian_rhythm2.00297592
22MP0002736_abnormal_nociception_after1.97251210
23MP0005645_abnormal_hypothalamus_physiol1.94790479
24MP0009046_muscle_twitch1.93696513
25MP0003121_genomic_imprinting1.93283300
26MP0002064_seizures1.88347488
27MP0003122_maternal_imprinting1.85015679
28MP0005646_abnormal_pituitary_gland1.81642685
29MP0002272_abnormal_nervous_system1.80112775
30MP0002733_abnormal_thermal_nociception1.79562075
31MP0002184_abnormal_innervation1.78659233
32MP0002557_abnormal_social/conspecific_i1.74977837
33MP0002067_abnormal_sensory_capabilities1.74679896
34MP0001440_abnormal_grooming_behavior1.73596946
35MP0006292_abnormal_olfactory_placode1.70701388
36MP0009780_abnormal_chondrocyte_physiolo1.68944621
37MP0001984_abnormal_olfaction1.68597364
38MP0001970_abnormal_pain_threshold1.60465281
39MP0006072_abnormal_retinal_apoptosis1.60211419
40MP0010386_abnormal_urinary_bladder1.58835280
41MP0004142_abnormal_muscle_tone1.55103258
42MP0005410_abnormal_fertilization1.54900319
43MP0005386_behavior/neurological_phenoty1.53991149
44MP0004924_abnormal_behavior1.53991149
45MP0002102_abnormal_ear_morphology1.51946328
46MP0005551_abnormal_eye_electrophysiolog1.48764869
47MP0002163_abnormal_gland_morphology1.41749613
48MP0002909_abnormal_adrenal_gland1.34179118
49MP0000427_abnormal_hair_cycle1.32031178
50MP0004742_abnormal_vestibular_system1.30543829
51MP0004215_abnormal_myocardial_fiber1.29540793
52MP0001986_abnormal_taste_sensitivity1.29432263
53MP0004043_abnormal_pH_regulation1.28702386
54MP0004885_abnormal_endolymph1.27762650
55MP0003698_abnormal_male_reproductive1.27517420
56MP0003045_fibrosis1.26421839
57MP0003890_abnormal_embryonic-extraembry1.24379237
58MP0000631_abnormal_neuroendocrine_gland1.23568691
59MP0003195_calcinosis1.20072630
60MP0000566_synostosis1.19848438
61MP0002882_abnormal_neuron_morphology1.18845239
62MP0004133_heterotaxia1.17145117
63MP0004811_abnormal_neuron_physiology1.16927557
64MP0000955_abnormal_spinal_cord1.16540839
65MP0003646_muscle_fatigue1.12710964
66MP0002638_abnormal_pupillary_reflex1.09285067
67MP0005253_abnormal_eye_physiology1.08008752
68MP0002751_abnormal_autonomic_nervous1.07955081
69MP0000372_irregular_coat_pigmentation1.06949704
70MP0002822_catalepsy1.05567133
71MP0008569_lethality_at_weaning1.03773463
72MP0008995_early_reproductive_senescence1.03524128
73MP0008057_abnormal_DNA_replication1.01974134
74MP0000015_abnormal_ear_pigmentation1.00380620
75MP0000647_abnormal_sebaceous_gland0.98843561
76MP0001905_abnormal_dopamine_level0.97542686
77MP0002152_abnormal_brain_morphology0.97294662
78MP0001929_abnormal_gametogenesis0.95224613
79MP0002234_abnormal_pharynx_morphology0.93595734
80MP0003718_maternal_effect0.92818929
81MP0002066_abnormal_motor_capabilities/c0.90652056
82MP0001963_abnormal_hearing_physiology0.89781816
83MP0003136_yellow_coat_color0.89497416
84MP0001485_abnormal_pinna_reflex0.89418158
85MP0002009_preneoplasia0.89255835
86MP0005499_abnormal_olfactory_system0.87276098
87MP0005394_taste/olfaction_phenotype0.87276098
88MP0002752_abnormal_somatic_nervous0.86616291
89MP0002928_abnormal_bile_duct0.86308968
90MP0000383_abnormal_hair_follicle0.84664352
91MP0002653_abnormal_ependyma_morphology0.84098024
92MP0008872_abnormal_physiological_respon0.83610046
93MP0005409_darkened_coat_color0.83213737
94MP0008058_abnormal_DNA_repair0.83103586
95MP0001299_abnormal_eye_distance/0.82062500
96MP0005248_abnormal_Harderian_gland0.81070791
97MP0002069_abnormal_eating/drinking_beha0.79778701
98MP0005623_abnormal_meninges_morphology0.79575262
99MP0004484_altered_response_of0.79290671
100MP0005195_abnormal_posterior_eye0.79204665
101MP0002876_abnormal_thyroid_physiology0.78944691
102MP0005379_endocrine/exocrine_gland_phen0.78288606
103MP0001529_abnormal_vocalization0.77776016
104MP0004858_abnormal_nervous_system0.77720237
105MP0002210_abnormal_sex_determination0.77267057
106MP0003861_abnormal_nervous_system0.76175183
107MP0000026_abnormal_inner_ear0.75454554
108MP0005187_abnormal_penis_morphology0.75352724
109MP0005171_absent_coat_pigmentation0.74835038
110MP0003633_abnormal_nervous_system0.74535548
111MP0001177_atelectasis0.74035634
112MP0004085_abnormal_heartbeat0.71187801
113MP0002229_neurodegeneration0.70245291
114MP0004145_abnormal_muscle_electrophysio0.69668536
115MP0003879_abnormal_hair_cell0.69539343
116MP0002160_abnormal_reproductive_system0.69414716
117MP0005174_abnormal_tail_pigmentation0.67561175
118MP0008789_abnormal_olfactory_epithelium0.66186350
119MP0003631_nervous_system_phenotype0.65805547
120MP0008961_abnormal_basal_metabolism0.65673675
121MP0010234_abnormal_vibrissa_follicle0.65561558
122MP0002938_white_spotting0.64698000
123MP0004233_abnormal_muscle_weight0.64653065

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)4.02537865
2Absent/shortened dynein arms (HP:0200106)4.02537865
3Focal motor seizures (HP:0011153)3.87174396
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.85122359
5Progressive cerebellar ataxia (HP:0002073)3.56779483
6Febrile seizures (HP:0002373)3.35040601
7Epileptic encephalopathy (HP:0200134)3.28001642
8Abnormal respiratory motile cilium physiology (HP:0012261)3.27327730
9Abnormal ciliary motility (HP:0012262)3.18179525
10Volvulus (HP:0002580)3.06837551
11Abnormality of the renal cortex (HP:0011035)3.00064218
12Focal seizures (HP:0007359)2.92071638
13Atonic seizures (HP:0010819)2.81120787
14Excessive salivation (HP:0003781)2.79375693
15Drooling (HP:0002307)2.79375693
16Broad-based gait (HP:0002136)2.75993377
17Renal cortical cysts (HP:0000803)2.70891426
18Abnormal respiratory epithelium morphology (HP:0012253)2.68320035
19Abnormal respiratory motile cilium morphology (HP:0005938)2.68320035
20Intestinal atresia (HP:0011100)2.67796086
21Protruding tongue (HP:0010808)2.63752999
22Gait imbalance (HP:0002141)2.60311645
23Polyphagia (HP:0002591)2.56317084
24Aqueductal stenosis (HP:0002410)2.55470466
25Hyperventilation (HP:0002883)2.54381650
26Rhinitis (HP:0012384)2.54010371
27Papillary thyroid carcinoma (HP:0002895)2.50045261
28Medial flaring of the eyebrow (HP:0010747)2.48905739
29Abnormal hair whorl (HP:0010721)2.41819674
30Myokymia (HP:0002411)2.40210329
31Nephronophthisis (HP:0000090)2.39669374
32Pancreatic fibrosis (HP:0100732)2.39547456
33Widely spaced teeth (HP:0000687)2.39505664
34Lissencephaly (HP:0001339)2.32618978
35Abnormality of the nasal septum (HP:0000419)2.31428603
36Type II lissencephaly (HP:0007260)2.28110780
37Chronic hepatic failure (HP:0100626)2.26525171
38Genital tract atresia (HP:0001827)2.25109494
39Median cleft lip (HP:0000161)2.24718570
40Oligodactyly (hands) (HP:0001180)2.23345877
41Pachygyria (HP:0001302)2.18381140
42Tubulointerstitial nephritis (HP:0001970)2.16261826
43Hypsarrhythmia (HP:0002521)2.15852527
44Congenital primary aphakia (HP:0007707)2.15386588
45Visual hallucinations (HP:0002367)2.14696999
46Molar tooth sign on MRI (HP:0002419)2.13827991
47Abnormality of midbrain morphology (HP:0002418)2.13827991
48Congenital stationary night blindness (HP:0007642)2.11816787
49Macroorchidism (HP:0000053)2.10962602
50Genetic anticipation (HP:0003743)2.08308256
51Abnormality of the renal medulla (HP:0100957)2.08215995
52Absence seizures (HP:0002121)2.08083064
53Hepatoblastoma (HP:0002884)2.07609244
54Inappropriate behavior (HP:0000719)2.06639696
55Exotropia (HP:0000577)2.01646858
56Fair hair (HP:0002286)2.01338807
57Narrow forehead (HP:0000341)2.00396504
58Polydipsia (HP:0001959)1.99823746
59Abnormal drinking behavior (HP:0030082)1.99823746
60Inability to walk (HP:0002540)1.99746007
61Hypothermia (HP:0002045)1.99453492
62Absent eyebrow (HP:0002223)1.99257667
63Congenital hepatic fibrosis (HP:0002612)1.99030966
64Vaginal atresia (HP:0000148)1.98986350
65Abnormality of the labia minora (HP:0012880)1.98921529
66Abnormality of salivation (HP:0100755)1.98733662
67Gastroesophageal reflux (HP:0002020)1.98217960
68Large for gestational age (HP:0001520)1.98185717
69Generalized hypopigmentation of hair (HP:0011358)1.97237492
70Megalencephaly (HP:0001355)1.95052487
71Absent speech (HP:0001344)1.93499621
72Retinal dysplasia (HP:0007973)1.93179980
73Poor coordination (HP:0002370)1.92741190
74Truncal ataxia (HP:0002078)1.91497565
75Gaze-evoked nystagmus (HP:0000640)1.90857570
76True hermaphroditism (HP:0010459)1.90735544
77Generalized tonic-clonic seizures (HP:0002069)1.90421641
78Abnormality of incisor morphology (HP:0011063)1.90051670
79Abnormal biliary tract physiology (HP:0012439)1.88539978
80Bile duct proliferation (HP:0001408)1.88539978
81Urinary bladder sphincter dysfunction (HP:0002839)1.87622580
82Nephrogenic diabetes insipidus (HP:0009806)1.87567580
83Tubular atrophy (HP:0000092)1.87377729
84Neoplasm of the oral cavity (HP:0100649)1.87097131
85Hip dysplasia (HP:0001385)1.86866446
86Postaxial foot polydactyly (HP:0001830)1.83927153
87Progressive inability to walk (HP:0002505)1.82798632
88Obsessive-compulsive behavior (HP:0000722)1.82726731
89Optic nerve hypoplasia (HP:0000609)1.82654605
90Dialeptic seizures (HP:0011146)1.82441634
91Blue irides (HP:0000635)1.82403245
92Abolished electroretinogram (ERG) (HP:0000550)1.82110174
93Dysdiadochokinesis (HP:0002075)1.77939806
94Aplasia/Hypoplasia of the tibia (HP:0005772)1.77531848
95Midline defect of the nose (HP:0004122)1.77110919
96Ketoacidosis (HP:0001993)1.76889910
97Agitation (HP:0000713)1.76483330
98Left ventricular hypertrophy (HP:0001712)1.75596404
99Cerebellar dysplasia (HP:0007033)1.75097929
100Anencephaly (HP:0002323)1.74798897
101Cutaneous finger syndactyly (HP:0010554)1.74778161
102Stomach cancer (HP:0012126)1.74701152
103Progressive macrocephaly (HP:0004481)1.74240236
104Truncal obesity (HP:0001956)1.73861353
105Attenuation of retinal blood vessels (HP:0007843)1.73226084
106Highly arched eyebrow (HP:0002553)1.72105989
107Tubulointerstitial abnormality (HP:0001969)1.71867761
108Narrow nasal bridge (HP:0000446)1.71668252
109Sclerocornea (HP:0000647)1.71451405
110Limb dystonia (HP:0002451)1.71415179
111Short foot (HP:0001773)1.71308925
112Furrowed tongue (HP:0000221)1.70556574
113Infertility (HP:0000789)1.70405357
114Prominent nasal bridge (HP:0000426)1.70163485
115Amyotrophic lateral sclerosis (HP:0007354)1.69905270
116Colon cancer (HP:0003003)1.68815648
117Impaired smooth pursuit (HP:0007772)1.68553689
118Gastrointestinal atresia (HP:0002589)1.68141036
119Male pseudohermaphroditism (HP:0000037)1.67821102
120Labial hypoplasia (HP:0000066)1.67808510
121Impaired vibration sensation in the lower limbs (HP:0002166)1.67322045
122Aplasia/Hypoplasia of the lens (HP:0008063)1.66884561
123Action tremor (HP:0002345)1.65633358
124Postaxial hand polydactyly (HP:0001162)1.65527211
125Epileptiform EEG discharges (HP:0011182)1.65487183
126Abnormality of the corticospinal tract (HP:0002492)1.65486408
127Decreased central vision (HP:0007663)1.64594085
128Aplasia involving bones of the upper limbs (HP:0009823)1.64364794
129Aplasia of the phalanges of the hand (HP:0009802)1.64364794
130Aplasia involving bones of the extremities (HP:0009825)1.64364794
131Pancreatic cysts (HP:0001737)1.63989458
132Short tibia (HP:0005736)1.63879398
133Aplasia/Hypoplasia of the tongue (HP:0010295)1.63349779
134Acute necrotizing encephalopathy (HP:0006965)1.62617866
135Absent frontal sinuses (HP:0002688)1.60967503
136Thyroid carcinoma (HP:0002890)1.60938661
137Cupped ear (HP:0000378)1.60450488
138Specific learning disability (HP:0001328)1.60423898
139Amblyopia (HP:0000646)1.60391285
140Astigmatism (HP:0000483)1.60276719
141Hemiparesis (HP:0001269)1.59959757
142Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.59653015
143Cystic liver disease (HP:0006706)1.59402073
144EEG with generalized epileptiform discharges (HP:0011198)1.58512980
145Autism (HP:0000717)1.56487585
146Hyperkalemia (HP:0002153)1.56372181

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.76522103
2NTRK33.35782046
3MAP3K43.14891534
4MAP2K73.11230156
5NTRK22.81570683
6CASK2.74014190
7MAPK132.54835724
8TNIK2.48958178
9PNCK2.43535756
10MAP4K22.30518374
11PINK12.06529931
12TRIM281.94633912
13SIK21.94368276
14BMPR1B1.90105827
15SIK31.72919642
16MAP3K91.72068949
17ADRBK21.66675594
18CAMK1G1.64353155
19ACVR1B1.63576946
20ERBB31.63449495
21AKT31.60101157
22MINK11.47733125
23MAP2K41.45507896
24INSRR1.41968732
25WNK11.39019377
26PRKD31.38915800
27EPHA41.38194344
28SGK21.34477890
29PIK3CA1.33385644
30GRK11.31155058
31GRK71.26941150
32BMPR21.24495855
33MAP3K121.23915401
34MAPK151.22306030
35OXSR11.14590411
36FRK1.13420840
37WNK31.12654039
38BCR1.05803274
39MKNK21.03412629
40TAOK31.03148638
41MAP3K21.02486760
42KSR11.02321170
43CDK50.99509927
44SRPK10.98349860
45PRPF4B0.95464560
46OBSCN0.92893098
47MAP3K60.91269555
48CAMKK20.90894360
49RIPK40.89015368
50PLK20.88062230
51STK380.87975260
52CAMK2A0.87777235
53SGK4940.84778594
54SGK2230.84778594
55CSNK1G20.83868988
56PHKG20.83281447
57PHKG10.83281447
58NUAK10.81957067
59SGK10.81292524
60DYRK20.80492859
61DAPK20.79933454
62GRK50.79351158
63FGFR30.78761265
64EPHA30.77736307
65CDK30.76362840
66NTRK10.76164473
67SGK30.75595119
68PRKCE0.74788719
69MARK20.68023266
70DYRK1A0.67622607
71FGFR20.67102554
72WNK40.67099963
73HIPK20.66625171
74PRKCH0.66218066
75UHMK10.65609366
76TAOK10.62426465
77CSNK1A1L0.62121779
78PRKCG0.61718454
79CAMK1D0.61404691
80FER0.60342765
81DMPK0.59949619
82RPS6KB10.59028355
83NEK60.58149476
84TXK0.58098232
85STK110.57730171
86ZAK0.56830293
87CDC42BPA0.55962066
88PTK2B0.55851183
89NLK0.55794343
90MST40.55464639
91PRKG10.52750142
92CSNK1G30.52672964
93CSNK1G10.51654579
94BRD40.51450999
95PRKACA0.49623961
96MUSK0.47417524
97CAMK10.46910372
98PAK30.45793586
99FGR0.45376243
100JAK30.44467075
101CAMK2D0.44332038
102GSK3B0.44264915
103PRKACB0.43954706
104MAPK100.43291419
105PKN10.43275880
106JAK10.43174776
107CAMK40.42536752
108RET0.41741011
109TNK20.41077648
110CSNK1D0.40714097
111CDK190.40482362
112PRKAA10.39902334
113ADRBK10.39711367
114STK390.39606947
115CSNK1E0.39167886
116STK38L0.38914802
117STK30.38693432
118CDK120.37999755
119RPS6KA30.37936014
120FES0.37212800
121ALK0.37004190
122RPS6KA20.36060725
123MAPK80.35710817
124CSNK1A10.35018165
125PRKCZ0.35003239
126IRAK10.34556519
127CCNB10.32503367
128CAMK2B0.31668085
129ATM0.31276280
130PLK30.31160301
131PRKCI0.31026139
132YES10.29225333
133ROCK10.28197879
134ERBB20.27875641
135PRKCA0.27743850

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.96746021
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.37348365
3Circadian entrainment_Homo sapiens_hsa047132.27306871
4Butanoate metabolism_Homo sapiens_hsa006502.26107161
5Amphetamine addiction_Homo sapiens_hsa050312.20871844
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.20603415
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.19071534
8Long-term potentiation_Homo sapiens_hsa047202.15812832
9Insulin secretion_Homo sapiens_hsa049112.11216975
10Glutamatergic synapse_Homo sapiens_hsa047242.03563880
11Taste transduction_Homo sapiens_hsa047422.01120545
12Serotonergic synapse_Homo sapiens_hsa047261.97719929
13Morphine addiction_Homo sapiens_hsa050321.96448180
14Dopaminergic synapse_Homo sapiens_hsa047281.94123344
15GABAergic synapse_Homo sapiens_hsa047271.90169232
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.88013632
17Protein export_Homo sapiens_hsa030601.83343064
18Renin secretion_Homo sapiens_hsa049241.79028625
19Olfactory transduction_Homo sapiens_hsa047401.77592109
20Cholinergic synapse_Homo sapiens_hsa047251.70261706
21Synaptic vesicle cycle_Homo sapiens_hsa047211.67254346
22Cocaine addiction_Homo sapiens_hsa050301.66119372
23Dorso-ventral axis formation_Homo sapiens_hsa043201.60019033
24Propanoate metabolism_Homo sapiens_hsa006401.56716085
25Salivary secretion_Homo sapiens_hsa049701.55361678
26Phototransduction_Homo sapiens_hsa047441.53505148
27Type II diabetes mellitus_Homo sapiens_hsa049301.50709419
28Long-term depression_Homo sapiens_hsa047301.49553240
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.47250823
30Calcium signaling pathway_Homo sapiens_hsa040201.44885893
31Oxidative phosphorylation_Homo sapiens_hsa001901.42573008
32Regulation of autophagy_Homo sapiens_hsa041401.41361490
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.35988675
34Basal transcription factors_Homo sapiens_hsa030221.31070496
35Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.29595285
36Linoleic acid metabolism_Homo sapiens_hsa005911.29408113
37Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.29261951
38cAMP signaling pathway_Homo sapiens_hsa040241.29028496
39Nitrogen metabolism_Homo sapiens_hsa009101.28104872
40GnRH signaling pathway_Homo sapiens_hsa049121.27572902
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.26261710
42Axon guidance_Homo sapiens_hsa043601.26038483
43Oxytocin signaling pathway_Homo sapiens_hsa049211.25751984
44Fanconi anemia pathway_Homo sapiens_hsa034601.25639449
45Gastric acid secretion_Homo sapiens_hsa049711.24983952
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24360548
47Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.21120077
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.20154525
49Tryptophan metabolism_Homo sapiens_hsa003801.19304604
50Estrogen signaling pathway_Homo sapiens_hsa049151.18430989
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.18404663
52Circadian rhythm_Homo sapiens_hsa047101.16032352
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13355781
54ErbB signaling pathway_Homo sapiens_hsa040121.09466350
55Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08884283
56Parkinsons disease_Homo sapiens_hsa050121.05292849
57Non-homologous end-joining_Homo sapiens_hsa034501.04535647
58Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01756530
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01547930
60Vascular smooth muscle contraction_Homo sapiens_hsa042701.00968518
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.00602657
62Gap junction_Homo sapiens_hsa045401.00332553
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.97454726
64Melanogenesis_Homo sapiens_hsa049160.96132538
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.95999003
66Choline metabolism in cancer_Homo sapiens_hsa052310.93604128
67Peroxisome_Homo sapiens_hsa041460.92297180
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.92184937
69MAPK signaling pathway_Homo sapiens_hsa040100.89524349
70Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.87593744
71Steroid biosynthesis_Homo sapiens_hsa001000.85737487
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85715139
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84553781
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.84493119
75Homologous recombination_Homo sapiens_hsa034400.83664726
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82449657
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82224834
78Caffeine metabolism_Homo sapiens_hsa002320.81961318
79Ras signaling pathway_Homo sapiens_hsa040140.80963805
80Prolactin signaling pathway_Homo sapiens_hsa049170.80867661
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80719951
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.80100704
83Oocyte meiosis_Homo sapiens_hsa041140.79935375
84Glioma_Homo sapiens_hsa052140.79666468
85ABC transporters_Homo sapiens_hsa020100.79018600
86Glucagon signaling pathway_Homo sapiens_hsa049220.78244245
87Wnt signaling pathway_Homo sapiens_hsa043100.77170345
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76599033
89Dilated cardiomyopathy_Homo sapiens_hsa054140.76376642
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74524694
91Endometrial cancer_Homo sapiens_hsa052130.73397799
92beta-Alanine metabolism_Homo sapiens_hsa004100.73096857
93Alzheimers disease_Homo sapiens_hsa050100.72973963
94Fatty acid elongation_Homo sapiens_hsa000620.72962265
95Pancreatic secretion_Homo sapiens_hsa049720.72781827
96RNA degradation_Homo sapiens_hsa030180.72494604
97Type I diabetes mellitus_Homo sapiens_hsa049400.71151990
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70665561
99Fatty acid metabolism_Homo sapiens_hsa012120.70541474
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.70415698
101Selenocompound metabolism_Homo sapiens_hsa004500.69134180
102Chemical carcinogenesis_Homo sapiens_hsa052040.66341710
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.65953347
104Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65929527
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65721925
106Thyroid hormone synthesis_Homo sapiens_hsa049180.63801770
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63661370
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62157725
109Huntingtons disease_Homo sapiens_hsa050160.61070211
110Collecting duct acid secretion_Homo sapiens_hsa049660.60901445
111Retinol metabolism_Homo sapiens_hsa008300.60564313
112Mineral absorption_Homo sapiens_hsa049780.58471896
113Ether lipid metabolism_Homo sapiens_hsa005650.58028516
114Ovarian steroidogenesis_Homo sapiens_hsa049130.57698647
115Colorectal cancer_Homo sapiens_hsa052100.56781587
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.56621774
117Renal cell carcinoma_Homo sapiens_hsa052110.54453076
118Alcoholism_Homo sapiens_hsa050340.52260793
119Prostate cancer_Homo sapiens_hsa052150.52028203
120Rap1 signaling pathway_Homo sapiens_hsa040150.51916876
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51700286
122Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51291336
123Neurotrophin signaling pathway_Homo sapiens_hsa047220.51211459
124Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50407359
125African trypanosomiasis_Homo sapiens_hsa051430.48554173
126Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47976465
127Inositol phosphate metabolism_Homo sapiens_hsa005620.47568471
128Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45608163
129T cell receptor signaling pathway_Homo sapiens_hsa046600.45217553
130Autoimmune thyroid disease_Homo sapiens_hsa053200.44497978
131Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43645338
132Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43549321
133Lysine degradation_Homo sapiens_hsa003100.43486224
134Chemokine signaling pathway_Homo sapiens_hsa040620.43298227
135Pancreatic cancer_Homo sapiens_hsa052120.43253373
136Cardiac muscle contraction_Homo sapiens_hsa042600.43137489
137Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42761063
138Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41568805
139Insulin signaling pathway_Homo sapiens_hsa049100.40527660
140Fatty acid degradation_Homo sapiens_hsa000710.40084149
141VEGF signaling pathway_Homo sapiens_hsa043700.39692801
142Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39417553
143mTOR signaling pathway_Homo sapiens_hsa041500.39362608
144Glycerolipid metabolism_Homo sapiens_hsa005610.39218130
145Folate biosynthesis_Homo sapiens_hsa007900.37913517
146Hedgehog signaling pathway_Homo sapiens_hsa043400.36426253
147Osteoclast differentiation_Homo sapiens_hsa043800.36416228
148Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34918642
149Sphingolipid metabolism_Homo sapiens_hsa006000.34028563

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