SCARA3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glial cell proliferation (GO:0014009)5.76516850
2chondrocyte proliferation (GO:0035988)4.39693074
3dermatan sulfate biosynthetic process (GO:0030208)4.35248382
4positive regulation of cellular amide metabolic process (GO:0034250)4.29528099
5negative regulation of amyloid precursor protein catabolic process (GO:1902992)4.21202697
6protein heterotrimerization (GO:0070208)4.16991238
7dermatan sulfate metabolic process (GO:0030205)4.06359840
8collagen fibril organization (GO:0030199)4.05225961
9G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.65681969
10lens fiber cell development (GO:0070307)3.63667136
11lung epithelium development (GO:0060428)3.57820138
12outer ear morphogenesis (GO:0042473)3.51799010
13cytoskeletal anchoring at plasma membrane (GO:0007016)3.50857420
14negative regulation of chondrocyte differentiation (GO:0032331)3.40828312
15chondroitin sulfate catabolic process (GO:0030207)3.38534378
16planar cell polarity pathway involved in neural tube closure (GO:0090179)3.36512104
17bone trabecula formation (GO:0060346)3.33310417
18protein retention in ER lumen (GO:0006621)3.29353047
19L-serine transport (GO:0015825)3.28382779
20negative regulation of astrocyte differentiation (GO:0048712)3.21923609
21cell-substrate junction assembly (GO:0007044)3.21801805
22regulation of beta-amyloid formation (GO:1902003)3.21553379
23peripheral nervous system axon ensheathment (GO:0032292)3.20924075
24myelination in peripheral nervous system (GO:0022011)3.20924075
25regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.20654503
26blood vessel maturation (GO:0001955)3.20273347
27sequestering of extracellular ligand from receptor (GO:0035581)3.19496685
28basement membrane organization (GO:0071711)3.18667899
29alanine transport (GO:0032328)3.18253700
30maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.11996497
31cellular response to cholesterol (GO:0071397)3.10731196
32adherens junction assembly (GO:0034333)3.10057236
33collagen metabolic process (GO:0032963)3.09840853
34regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.09448144
35cell migration involved in heart development (GO:0060973)3.07990805
36positive regulation of osteoblast proliferation (GO:0033690)3.07400494
37collagen catabolic process (GO:0030574)3.06803151
38extracellular fibril organization (GO:0043206)3.05373383
39barbed-end actin filament capping (GO:0051016)3.04341752
40epithelial cell-cell adhesion (GO:0090136)3.01765225
41peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.01068189
42skin morphogenesis (GO:0043589)2.99819381
43extracellular matrix disassembly (GO:0022617)2.99037711
44astrocyte development (GO:0014002)2.97949313
45response to gravity (GO:0009629)2.97717711
46lung-associated mesenchyme development (GO:0060484)2.96673291
47positive regulation of glycogen biosynthetic process (GO:0045725)2.96624166
48positive regulation of extracellular matrix organization (GO:1903055)2.93814759
49metanephric mesenchyme development (GO:0072075)2.93285688
50multicellular organismal macromolecule metabolic process (GO:0044259)2.92508280
51synaptic vesicle docking involved in exocytosis (GO:0016081)2.92212161
52axon extension involved in axon guidance (GO:0048846)2.91841246
53neuron projection extension involved in neuron projection guidance (GO:1902284)2.91841246
54multicellular organismal catabolic process (GO:0044243)2.91822087
55semaphorin-plexin signaling pathway (GO:0071526)2.91738699
56ovulation cycle (GO:0042698)2.91012331
57chondroitin sulfate biosynthetic process (GO:0030206)2.90358668
58cell adhesion mediated by integrin (GO:0033627)2.89869582
59lateral sprouting from an epithelium (GO:0060601)2.89794830
60astrocyte differentiation (GO:0048708)2.89421315
61regulation of extracellular matrix disassembly (GO:0010715)2.89014163
62negative regulation of catenin import into nucleus (GO:0035414)2.88180709
63craniofacial suture morphogenesis (GO:0097094)2.87617269
64apoptotic cell clearance (GO:0043277)2.86468372
65Golgi transport vesicle coating (GO:0048200)2.85871790
66COPI coating of Golgi vesicle (GO:0048205)2.85871790
67multicellular organismal metabolic process (GO:0044236)2.84991613
68retina vasculature morphogenesis in camera-type eye (GO:0061299)2.83276414
69paraxial mesoderm development (GO:0048339)2.83149663
70focal adhesion assembly (GO:0048041)2.82991763
71cell-substrate adherens junction assembly (GO:0007045)2.82991763
72vascular endothelial growth factor signaling pathway (GO:0038084)2.82873867
73negative regulation of smoothened signaling pathway (GO:0045879)2.81718497
74endothelial cell morphogenesis (GO:0001886)2.81148142
75non-canonical Wnt signaling pathway (GO:0035567)2.80375425
76cellular potassium ion homeostasis (GO:0030007)2.79191442
77negative regulation of cartilage development (GO:0061037)2.77049339
78regulation of amyloid precursor protein catabolic process (GO:1902991)2.76826644
79serine transport (GO:0032329)2.74837853
80cell proliferation involved in metanephros development (GO:0072203)2.73977813
81kidney mesenchyme development (GO:0072074)2.72996329
82positive regulation of blood vessel endothelial cell migration (GO:0043536)2.72954785
83branching involved in salivary gland morphogenesis (GO:0060445)2.70199139
84notochord development (GO:0030903)2.68037398
85negative regulation of osteoblast proliferation (GO:0033689)2.67632746
86Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.66954817
87amino acid import (GO:0043090)2.65751406
88mesenchymal-epithelial cell signaling (GO:0060638)2.65317245
89mesenchyme morphogenesis (GO:0072132)2.65244832
90cochlea morphogenesis (GO:0090103)2.64746082
91nephron tubule formation (GO:0072079)2.63772837
92glomerular basement membrane development (GO:0032836)2.61017738
93regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.60926689
94regulation of early endosome to late endosome transport (GO:2000641)2.60177698
95negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.59912089
96vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.59168343
97sodium ion export (GO:0071436)2.59122206
98extracellular structure organization (GO:0043062)2.59114534
99regulation of axon extension involved in axon guidance (GO:0048841)2.59002062
100keratan sulfate catabolic process (GO:0042340)2.58466496
101tooth mineralization (GO:0034505)2.58265307
102regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.57576246
103endodermal cell differentiation (GO:0035987)2.57164301
104regulation of astrocyte differentiation (GO:0048710)2.57135869
105neuron projection regeneration (GO:0031102)2.56214322
106middle ear morphogenesis (GO:0042474)2.55017551
107protein localization to endosome (GO:0036010)2.54830083
108anatomical structure regression (GO:0060033)2.54791296
109positive regulation of receptor recycling (GO:0001921)2.53934882
110dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.53702026
111regulation of establishment of planar polarity (GO:0090175)2.53505333
112hemidesmosome assembly (GO:0031581)2.53423306
113cellular response to sterol (GO:0036315)2.53264750
114fibril organization (GO:0097435)2.53254659
115adhesion of symbiont to host (GO:0044406)2.52932507
116negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.52321893
117regulation of extracellular matrix organization (GO:1903053)2.52071128
118negative regulation of sodium ion transport (GO:0010766)2.51344566
119adhesion of symbiont to host cell (GO:0044650)2.50672439
120virion attachment to host cell (GO:0019062)2.50672439
121regulation of cell fate specification (GO:0042659)2.50577085
122hippo signaling (GO:0035329)2.50498215
123stress fiber assembly (GO:0043149)2.50367219
124positive regulation of cartilage development (GO:0061036)2.49166464
125positive regulation of mesenchymal cell proliferation (GO:0002053)2.48334461
126C4-dicarboxylate transport (GO:0015740)2.48183430
127type B pancreatic cell proliferation (GO:0044342)2.47884813
128positive regulation of glycogen metabolic process (GO:0070875)2.47713121
129chondroitin sulfate metabolic process (GO:0030204)2.47657664
130postsynaptic membrane organization (GO:0001941)2.46445411
131cellular sodium ion homeostasis (GO:0006883)2.45939361
132wound healing, spreading of cells (GO:0044319)2.44670748
133glial cell migration (GO:0008347)2.43813479
134regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.42597994
135positive regulation of axon extension (GO:0045773)2.42385976
136cortical actin cytoskeleton organization (GO:0030866)2.41102906
137metanephric nephron tubule development (GO:0072234)2.40928597
138metanephric tubule development (GO:0072170)2.40928597
139embryonic cranial skeleton morphogenesis (GO:0048701)2.40869361
140regulation of osteoblast proliferation (GO:0033688)2.40833014
141extracellular matrix assembly (GO:0085029)2.40668648
142protein targeting to plasma membrane (GO:0072661)2.40369626
143axon extension (GO:0048675)2.39891465
144extracellular matrix organization (GO:0030198)2.38968268
145endocardial cushion morphogenesis (GO:0003203)2.38566858
146cell migration involved in sprouting angiogenesis (GO:0002042)2.38408833
147cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.38363718
148regulation of tight junction assembly (GO:2000810)2.38059021
149cell aggregation (GO:0098743)2.38009098
150muscle cell migration (GO:0014812)2.36780909
151wound healing, spreading of epidermal cells (GO:0035313)2.36546467
152cGMP-mediated signaling (GO:0019934)2.36123752
153substrate adhesion-dependent cell spreading (GO:0034446)2.36089308
154cell volume homeostasis (GO:0006884)2.35861184

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human4.69167331
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.58324400
3PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.82600433
4RARG_19884340_ChIP-ChIP_MEFs_Mouse2.82476008
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.50219045
6EED_16625203_ChIP-ChIP_MESCs_Mouse2.45181513
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41375163
8CLOCK_20551151_ChIP-Seq_293T_Human2.29927581
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.29174565
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.23206685
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.23206685
12ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.20800441
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.16860201
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09873445
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.08970536
16* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.08568209
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.06524411
18* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.04207418
19ELK3_25401928_ChIP-Seq_HUVEC_Human1.94092109
20* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.88596221
21AR_21572438_ChIP-Seq_LNCaP_Human1.87823894
22* LXR_22292898_ChIP-Seq_THP-1_Human1.82557476
23ZNF263_19887448_ChIP-Seq_K562_Human1.80572336
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.77237451
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.75537455
26EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.70413419
27* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.68287001
28ESR1_21235772_ChIP-Seq_MCF-7_Human1.67640007
29* EP300_21415370_ChIP-Seq_HL-1_Mouse1.66748307
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.64893787
31EZH2_27304074_Chip-Seq_ESCs_Mouse1.63469470
32* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.62010905
33* CJUN_26792858_Chip-Seq_BT549_Human1.61859275
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.61563453
35KDM2B_26808549_Chip-Seq_SUP-B15_Human1.60486776
36* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.55589788
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.55364926
38TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.54896240
39TP53_18474530_ChIP-ChIP_U2OS_Human1.54410833
40ZFP281_27345836_Chip-Seq_ESCs_Mouse1.53148431
41TP53_20018659_ChIP-ChIP_R1E_Mouse1.52628369
42NRF2_20460467_ChIP-Seq_MEFs_Mouse1.50554452
43NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.50554452
44RACK7_27058665_Chip-Seq_MCF-7_Human1.48471595
45EZH2_27294783_Chip-Seq_ESCs_Mouse1.45977000
46TP53_22127205_ChIP-Seq_IMR90_Human1.45730099
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.45669387
48DROSHA_22980978_ChIP-Seq_HELA_Human1.43842356
49NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.41385932
50EZH2_22144423_ChIP-Seq_EOC_Human1.41075611
51TP53_23651856_ChIP-Seq_MEFs_Mouse1.40151251
52CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.38892642
53TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.38232537
54SOX9_24532713_ChIP-Seq_HFSC_Mouse1.38103969
55* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.36793237
56IKZF1_21737484_ChIP-ChIP_HCT116_Human1.35539202
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.34711799
58TP53_16413492_ChIP-PET_HCT116_Human1.32914380
59RING1B_27294783_Chip-Seq_ESCs_Mouse1.31308908
60RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.30825763
61THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.30157241
62ESR1_20079471_ChIP-ChIP_T-47D_Human1.29889999
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.29230461
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29012480
65* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.26074940
66SMC3_22415368_ChIP-Seq_MEFs_Mouse1.26000025
67ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.24376551
68TET1_21490601_ChIP-Seq_MESCs_Mouse1.21814618
69UBF1/2_26484160_Chip-Seq_HMECs_Human1.21361238
70BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.21287645
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.21267005
72POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20541696
73WT1_19549856_ChIP-ChIP_CCG9911_Human1.20126337
74RXR_22108803_ChIP-Seq_LS180_Human1.19884574
75OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15769794
76HIF1A_21447827_ChIP-Seq_MCF-7_Human1.14806329
77SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14279664
78ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13961923
79CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.13932676
80* FOXO3_23340844_ChIP-Seq_DLD1_Human1.13724385
81ISL1_27105846_Chip-Seq_CPCs_Mouse1.13338418
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.12554508
83TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.12104372
84CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.10418429
85PPAR_26484153_Chip-Seq_NCI-H1993_Human1.09419093
86CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.09171558
87PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.08946756
88SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.08167789
89SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.06795303
90NFIB_24661679_ChIP-Seq_LUNG_Mouse1.06761019
91KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05743325
92RING1B_27294783_Chip-Seq_NPCs_Mouse1.05544221
93KDM2B_26808549_Chip-Seq_K562_Human1.05213414
94BRD4_25478319_ChIP-Seq_HGPS_Human1.04595712
95SMAD_19615063_ChIP-ChIP_OVARY_Human1.04545731
96ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.04540546
97ARNT_22903824_ChIP-Seq_MCF-7_Human1.04210557
98AHR_22903824_ChIP-Seq_MCF-7_Human1.04193178
99CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03810161
100KLF5_25053715_ChIP-Seq_YYC3_Human1.03798194
101SA1_22415368_ChIP-Seq_MEFs_Mouse1.03080321
102SMC4_20622854_ChIP-Seq_HELA_Human1.02337774
103TCF4_18268006_ChIP-ChIP_LS174T_Human1.02260329
104SOX2_20726797_ChIP-Seq_SW620_Human1.02254295
105ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.02163836
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01692846
107GATA2_21666600_ChIP-Seq_HMVEC_Human1.01438428
108CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.00812274
109SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.99335805
110TBX20_22328084_ChIP-Seq_HEART_Mouse0.97476962
111TBX20_22080862_ChIP-Seq_HEART_Mouse0.97476962
112TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96748991
113TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.96332033
114BCAT_22108803_ChIP-Seq_LS180_Human0.96085125
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93855876
116SMC1_22415368_ChIP-Seq_MEFs_Mouse0.93785109
117NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92848367
118ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92003398
119ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91288458
120SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.90537752
121SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.90537752
122P300_27058665_Chip-Seq_ZR-75-30cells_Human0.89529515
123NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.88389675
124UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.88069109
125JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87761812
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.87687198
127AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.87361621
128PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.87247319
129STAT6_21828071_ChIP-Seq_BEAS2B_Human0.86685802
130GBX2_23144817_ChIP-Seq_PC3_Human0.86339034
131MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.86018161

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.47312310
2MP0005503_abnormal_tendon_morphology4.52236424
3MP0005275_abnormal_skin_tensile4.27634968
4MP0003705_abnormal_hypodermis_morpholog3.79745767
5MP0003279_aneurysm3.29300699
6MP0009384_cardiac_valve_regurgitation3.00387063
7MP0010030_abnormal_orbit_morphology2.71222394
8MP0001958_emphysema2.65921306
9MP0000566_synostosis2.65009892
10MP0004272_abnormal_basement_membrane2.62096039
11MP0002254_reproductive_system_inflammat2.25777217
12MP0003300_gastrointestinal_ulcer2.20899270
13MP0005508_abnormal_skeleton_morphology2.13291545
14MP0009780_abnormal_chondrocyte_physiolo2.08843268
15MP0004858_abnormal_nervous_system2.06703306
16MP0003329_amyloid_beta_deposits1.95231620
17MP0005623_abnormal_meninges_morphology1.87546422
18MP0009250_abnormal_appendicular_skeleto1.86998505
19MP0003942_abnormal_urinary_system1.81402580
20MP0002877_abnormal_melanocyte_morpholog1.80141138
21MP0006054_spinal_hemorrhage1.78704235
22MP0004859_abnormal_synaptic_plasticity1.70083705
23MP0002060_abnormal_skin_morphology1.65698237
24MP0000537_abnormal_urethra_morphology1.65628508
25MP0002108_abnormal_muscle_morphology1.63091823
26MP0000534_abnormal_ureter_morphology1.62918423
27MP0003045_fibrosis1.62734057
28MP0002138_abnormal_hepatobiliary_system1.61770202
29MP0002295_abnormal_pulmonary_circulatio1.61070484
30MP0000049_abnormal_middle_ear1.60545629
31MP0001299_abnormal_eye_distance/1.59276436
32MP0002249_abnormal_larynx_morphology1.54000155
33MP0002928_abnormal_bile_duct1.52599372
34MP0005257_abnormal_intraocular_pressure1.51507108
35MP0002282_abnormal_trachea_morphology1.49094047
36MP0003115_abnormal_respiratory_system1.48247432
37MP0003950_abnormal_plasma_membrane1.47356970
38MP0010234_abnormal_vibrissa_follicle1.42238029
39MP0000428_abnormal_craniofacial_morphol1.41949596
40MP0002896_abnormal_bone_mineralization1.40949292
41MP0004134_abnormal_chest_morphology1.40133739
42MP0003690_abnormal_glial_cell1.33361464
43MP0003566_abnormal_cell_adhesion1.33102424
44MP0000163_abnormal_cartilage_morphology1.29517851
45MP0002089_abnormal_postnatal_growth/wei1.23596083
46MP0002115_abnormal_skeleton_extremities1.23439008
47MP0005377_hearing/vestibular/ear_phenot1.22596170
48MP0003878_abnormal_ear_physiology1.22596170
49MP0001348_abnormal_lacrimal_gland1.21002132
50MP0000751_myopathy1.19851212
51MP0003385_abnormal_body_wall1.19646225
52MP0010352_gastrointestinal_tract_polyps1.18307604
53MP0002233_abnormal_nose_morphology1.17804783
54MP0002168_other_aberrant_phenotype1.16489925
55MP0000462_abnormal_digestive_system1.16357093
56MP0003283_abnormal_digestive_organ1.14298996
57MP0005409_darkened_coat_color1.09104274
58MP0003091_abnormal_cell_migration1.08945952
59MP0003634_abnormal_glial_cell1.08899750
60MP0010368_abnormal_lymphatic_system1.04857975
61MP0003252_abnormal_bile_duct1.04467449
62MP0002932_abnormal_joint_morphology1.03133015
63MP0000762_abnormal_tongue_morphology1.02780593
64MP0000604_amyloidosis1.02557969
65MP0001915_intracranial_hemorrhage1.02465708
66MP0000003_abnormal_adipose_tissue1.01828079
67MP0003941_abnormal_skin_development1.01633335
68MP0001542_abnormal_bone_strength1.00862850
69MP0000733_abnormal_muscle_development1.00773619
70MP0003937_abnormal_limbs/digits/tail_de0.99406342
71MP0000579_abnormal_nail_morphology0.98131868
72MP0001346_abnormal_lacrimal_gland0.97747312
73MP0005023_abnormal_wound_healing0.97521791
74MP0005390_skeleton_phenotype0.96390956
75MP0002109_abnormal_limb_morphology0.96166709
76MP0004885_abnormal_endolymph0.93930489
77MP0005595_abnormal_vascular_smooth0.93083107
78MP0005084_abnormal_gallbladder_morpholo0.92991643
79MP0000767_abnormal_smooth_muscle0.92590830
80MP0002116_abnormal_craniofacial_bone0.92400616
81MP0005076_abnormal_cell_differentiation0.91672745
82MP0003755_abnormal_palate_morphology0.90551109
83MP0010678_abnormal_skin_adnexa0.90052858
84MP0006138_congestive_heart_failure0.87819329
85MP0005248_abnormal_Harderian_gland0.86615640
86MP0000432_abnormal_head_morphology0.86312171
87MP0000467_abnormal_esophagus_morphology0.85144393
88MP0000013_abnormal_adipose_tissue0.84956866
89MP0002998_abnormal_bone_remodeling0.84235591
90MP0003935_abnormal_craniofacial_develop0.84226216
91MP0009053_abnormal_anal_canal0.84171118
92MP0001243_abnormal_dermal_layer0.83497596
93MP0009379_abnormal_foot_pigmentation0.83483795
94MP0005165_increased_susceptibility_to0.83458098
95MP0000920_abnormal_myelination0.82334266
96MP0000647_abnormal_sebaceous_gland0.82214060
97MP0005220_abnormal_exocrine_pancreas0.81722342
98MP0003075_altered_response_to0.81689477
99MP0001270_distended_abdomen0.81588195
100MP0001849_ear_inflammation0.81537060
101MP0005167_abnormal_blood-brain_barrier0.80575092
102MP0005171_absent_coat_pigmentation0.80273146
103MP0001177_atelectasis0.79148717
104MP0000778_abnormal_nervous_system0.77460067
105MP0002113_abnormal_skeleton_development0.76108238
106MP0004233_abnormal_muscle_weight0.75118662
107MP0000759_abnormal_skeletal_muscle0.74343054
108MP0003011_delayed_dark_adaptation0.73409777
109MP0002128_abnormal_blood_circulation0.72676634
110MP0002697_abnormal_eye_size0.72519326
111MP0001614_abnormal_blood_vessel0.72437208
112MP0000749_muscle_degeneration0.71759598
113MP0002090_abnormal_vision0.71401078
114MP0002114_abnormal_axial_skeleton0.70796686
115MP0001853_heart_inflammation0.70322430
116MP0000383_abnormal_hair_follicle0.70077856
117MP0005164_abnormal_response_to0.70015002
118MP0000026_abnormal_inner_ear0.70005944
119MP0002933_joint_inflammation0.69749924
120MP0001879_abnormal_lymphatic_vessel0.66611018
121MP0002092_abnormal_eye_morphology0.65807927
122MP0005197_abnormal_uvea_morphology0.63517133
123MP0005388_respiratory_system_phenotype0.62855712
124MP0002133_abnormal_respiratory_system0.62855712
125MP0003453_abnormal_keratinocyte_physiol0.62033810
126MP0001502_abnormal_circadian_rhythm0.57303048
127MP0002925_abnormal_cardiovascular_devel0.56591444
128MP0000681_abnormal_thyroid_gland0.54925506
129MP0010771_integument_phenotype0.54071338

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.29190546
2Premature rupture of membranes (HP:0001788)4.56214930
3Broad metatarsal (HP:0001783)4.46363707
4Neonatal short-limb short stature (HP:0008921)4.41721917
5Aplasia involving bones of the upper limbs (HP:0009823)4.25486469
6Aplasia of the phalanges of the hand (HP:0009802)4.25486469
7Aplasia involving bones of the extremities (HP:0009825)4.25486469
8Shallow orbits (HP:0000586)4.18642032
9Ankle contracture (HP:0006466)3.85493780
10Atrophic scars (HP:0001075)3.82175489
11Aortic dissection (HP:0002647)3.70640461
12Megalencephaly (HP:0001355)3.53448837
13Abnormality of dentin (HP:0010299)3.37350967
14Biconcave vertebral bodies (HP:0004586)3.19653912
15Vascular tortuosity (HP:0004948)3.16627822
16Soft skin (HP:0000977)3.16438614
17Arterial tortuosity (HP:0005116)3.15188885
18Humeroradial synostosis (HP:0003041)3.14440378
19Synostosis involving the elbow (HP:0003938)3.14440378
20Fragile skin (HP:0001030)2.94068072
21Follicular hyperkeratosis (HP:0007502)2.92145053
22Bladder diverticulum (HP:0000015)2.79644758
23Hyperacusis (HP:0010780)2.77329374
24Aortic aneurysm (HP:0004942)2.76665640
25Coronal craniosynostosis (HP:0004440)2.76344662
26Dilatation of the ascending aorta (HP:0005111)2.65750612
27Cerebral aneurysm (HP:0004944)2.64379997
28Mitral valve prolapse (HP:0001634)2.64335035
29Bell-shaped thorax (HP:0001591)2.63245427
30Bronchomalacia (HP:0002780)2.61453449
31Wrist flexion contracture (HP:0001239)2.60371677
32Short hallux (HP:0010109)2.59259570
33Abnormality of the middle phalanges of the toes (HP:0010183)2.55824631
34Renal duplication (HP:0000075)2.54427423
35Type 1 muscle fiber predominance (HP:0003803)2.53875989
36Osteolytic defects of the phalanges of the hand (HP:0009771)2.53253455
37Osteolytic defects of the hand bones (HP:0009699)2.53253455
38Cervical subluxation (HP:0003308)2.52780092
39Short nail (HP:0001799)2.52100380
40Obstructive sleep apnea (HP:0002870)2.49062471
41Hyperextensible skin (HP:0000974)2.47229552
42Vertebral compression fractures (HP:0002953)2.46704706
43Tarsal synostosis (HP:0008368)2.45451338
44Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.44080865
45Aortic regurgitation (HP:0001659)2.43250893
46Peritonitis (HP:0002586)2.38337924
47Broad ribs (HP:0000885)2.36577634
48Onycholysis (HP:0001806)2.36322021
49Wormian bones (HP:0002645)2.36182316
50Facial shape deformation (HP:0011334)2.35689154
51Potter facies (HP:0002009)2.35689154
52Aplasia/Hypoplasia of the hallux (HP:0008362)2.35242312
53Hypoventilation (HP:0002791)2.32893876
54Mixed hearing impairment (HP:0000410)2.30564757
55Overgrowth (HP:0001548)2.29399400
56Blue sclerae (HP:0000592)2.28692080
57Insomnia (HP:0100785)2.25295646
58Deviation of the hallux (HP:0010051)2.22650567
59Synostosis involving bones of the feet (HP:0009140)2.21324306
60Synostosis involving bones of the lower limbs (HP:0009138)2.21324306
61Abnormality of skeletal muscle fiber size (HP:0012084)2.19153139
62Mild short stature (HP:0003502)2.17916686
63Epiphyseal dysplasia (HP:0002656)2.17623969
64Short 4th metacarpal (HP:0010044)2.14826499
65Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.14826499
66Mitral stenosis (HP:0001718)2.13736671
67Ectopia lentis (HP:0001083)2.13166700
68Spinal rigidity (HP:0003306)2.12478441
69Narrow nasal bridge (HP:0000446)2.11256093
70Turricephaly (HP:0000262)2.10590141
71Camptodactyly of toe (HP:0001836)2.09692642
72Slender build (HP:0001533)2.09595297
73Morphological abnormality of the middle ear (HP:0008609)2.08840898
74Aortic valve stenosis (HP:0001650)2.08561176
75Osteoarthritis (HP:0002758)2.07783277
76Wide anterior fontanel (HP:0000260)2.06669368
77Hallux valgus (HP:0001822)2.06415328
78Flat cornea (HP:0007720)2.06082935
79Natal tooth (HP:0000695)2.05073070
80Fibular aplasia (HP:0002990)2.04499449
81Joint laxity (HP:0001388)2.02886697
82Buphthalmos (HP:0000557)2.01983176
83Mildly elevated creatine phosphokinase (HP:0008180)2.00077897
84Elbow flexion contracture (HP:0002987)1.99916017
85Infantile muscular hypotonia (HP:0008947)1.99661784
86Distal upper limb amyotrophy (HP:0007149)1.98770172
87Upper limb amyotrophy (HP:0009129)1.98770172
88Abnormality of the acetabulum (HP:0003170)1.98039187
89Achilles tendon contracture (HP:0001771)1.97849601
90Disproportionate tall stature (HP:0001519)1.97624065
91Round ear (HP:0100830)1.96343954
92Back pain (HP:0003418)1.95925886
93Broad face (HP:0000283)1.95627696
94Mesangial abnormality (HP:0001966)1.95202453
95Deformed tarsal bones (HP:0008119)1.94830275
96Femoral bowing (HP:0002980)1.94552324
97Joint stiffness (HP:0001387)1.94338298
98Renovascular hypertension (HP:0100817)1.94232703
99Overriding aorta (HP:0002623)1.93396366
100Bowed forearm bones (HP:0003956)1.92735296
101Bowing of the arm (HP:0006488)1.92735296
102Arnold-Chiari malformation (HP:0002308)1.92511547
103Generalized amyotrophy (HP:0003700)1.92012210
104Protruding ear (HP:0000411)1.91701295
105Mitral regurgitation (HP:0001653)1.91414291
106Spondylolisthesis (HP:0003302)1.90723168
107Calcaneovalgus deformity (HP:0001848)1.90698594
108Synostosis of carpal bones (HP:0005048)1.89777881
109Spinal cord compression (HP:0002176)1.87968421
110Elfin facies (HP:0004428)1.87683532
111Genu recurvatum (HP:0002816)1.86364337
112Broad toe (HP:0001837)1.85892719
113Striae distensae (HP:0001065)1.83435047
114Abnormality of the 4th metacarpal (HP:0010012)1.83119457
115Venous abnormality (HP:0002624)1.83006459
116Ulnar bowing (HP:0003031)1.82169146
117Long toe (HP:0010511)1.81062391
118Increased connective tissue (HP:0009025)1.78785241
119Broad hallux (HP:0010055)1.78734624
120Broad long bones (HP:0005622)1.78454461
121Abnormality of the 2nd finger (HP:0004100)1.78334660
122Abnormal delivery (HP:0001787)1.76795869
123Recurrent corneal erosions (HP:0000495)1.75225364
124Bowel diverticulosis (HP:0005222)1.74617569
125Abnormal ossification of hand bones (HP:0005921)1.74371214
126Abnormality of the phalanges of the 2nd finger (HP:0009541)1.74229407
127Venous insufficiency (HP:0005293)1.74203607
128Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.74196487
129Advanced eruption of teeth (HP:0006288)1.74182425
130Limited hip movement (HP:0008800)1.73459625
131Abnormality of the Achilles tendon (HP:0005109)1.73386372
132Absent toe (HP:0010760)1.72934867
133Radial bowing (HP:0002986)1.71487601
134Increased variability in muscle fiber diameter (HP:0003557)1.69940627
135Right ventricular cardiomyopathy (HP:0011663)1.69915730
136Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.69685599
137Hydroureter (HP:0000072)1.69658020
138Congenital glaucoma (HP:0001087)1.69390062
139Absent frontal sinuses (HP:0002688)1.69359478
140Tibial bowing (HP:0002982)1.69229783
141Aplasia/Hypoplasia of the fibula (HP:0006492)1.68066836
142Limb-girdle muscle weakness (HP:0003325)1.67910890
143Partial duplication of the phalanx of hand (HP:0009999)1.67648808
144Aneurysm (HP:0002617)1.67405929
145Mesomelia (HP:0003027)1.67180616
146Premature skin wrinkling (HP:0100678)1.65326991

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR25.62289315
2TRIB34.66424874
3LMTK23.95843758
4SIK13.41025525
5EPHA42.80892566
6PDGFRA2.73049337
7LATS12.59411146
8PHKG22.53408617
9PHKG12.53408617
10RIPK12.51400524
11FGFR22.42233456
12ERN12.06577616
13TTN2.04274336
14PRKD32.03503496
15EPHB21.99662511
16TESK11.95021068
17ICK1.92191223
18EPHA21.85368148
19FER1.83875054
20PKN21.81200518
21FGFR11.65268052
22MARK11.58365807
23LIMK11.58095049
24PTK61.56725090
25SMG11.49709072
26NTRK11.45046528
27LATS21.42308236
28BMX1.41398238
29ERBB41.37907801
30TIE11.36567331
31EPHA31.33051819
32PTK21.31040450
33NTRK21.25737408
34PAK31.23109705
35MET1.23094076
36PAK41.18384299
37PBK1.15963600
38LRRK21.14787977
39ROCK11.14441974
40FRK1.08959397
41PDGFRB1.06681401
42EPHB11.05268861
43DMPK1.01670712
44FGFR41.00542160
45FGFR30.98731830
46RPS6KA20.97787339
47CAMK2B0.96336534
48PTK2B0.91792356
49MAP3K20.90292289
50PAK20.87708174
51MAP2K10.87476921
52ABL20.84140716
53ARAF0.82136279
54ROCK20.81544593
55NTRK30.77593250
56ILK0.75768680
57IRAK30.75026493
58MOS0.74336728
59MARK20.73372988
60PRKG20.73291061
61MST1R0.71966117
62ERBB20.71836032
63KSR20.71268515
64STK30.71245708
65NEK90.70969060
66MYLK0.69939298
67MAPKAPK30.69882962
68TYRO30.69233893
69CAMK1D0.68020241
70CAMK2D0.66698114
71PRKCH0.65465512
72BRSK10.65458754
73PRKCE0.65367367
74MAP3K70.64688102
75MELK0.64262137
76UHMK10.63442258
77RET0.63104040
78CDK80.61911887
79NEK60.61643848
80TRPM70.59820938
81ADRBK10.59000835
82TGFBR20.58691052
83CAMKK10.57811054
84PRKD20.56389816
85CAMK1G0.56047024
86CDK120.55198802
87CDK150.54341777
88MAP2K20.52028027
89CDK60.50918086
90PKN10.50341501
91SRC0.50254024
92CDK11A0.49795152
93TAOK20.48560721
94PIM20.47929796
95CDK180.47831415
96MAPKAPK50.47270359
97PAK60.47135831
98PDK30.46718497
99PDK40.46718497
100MAP3K60.46680524
101DAPK20.46572225
102MAPK150.46201351
103PRKD10.45930867
104FGR0.45079584
105DYRK1B0.44198802
106KSR10.43324329
107IGF1R0.43100009
108GSK3A0.42834345
109STK380.41266519
110INSR0.40980739
111CDK140.40931914
112CDC42BPA0.40843323
113STK38L0.40075348
114GRK50.39533856
115MAPK100.39225631
116TNIK0.38082946
117MUSK0.37594245
118AKT20.37449021
119SGK30.37211758
120PAK10.36963887
121MTOR0.36708509
122SCYL20.35784536
123WNK10.35550234
124PRPF4B0.35352291
125BRAF0.34857870
126PDPK10.34691771
127MAP3K80.33617747
128PIK3CA0.33280341
129MAPK40.32213083
130MST40.31780955
131CDK50.31026873
132ERBB30.29164179
133PRKCG0.28779083
134CAMK2G0.27370680
135EEF2K0.24722672
136NUAK10.24715775
137FYN0.24590780
138DAPK30.23461508
139MAPK120.23164143
140PLK20.22336356
141MINK10.21473762
142CSNK1A1L0.20251323
143CAMK2A0.20059684

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.25383844
2Fatty acid biosynthesis_Homo sapiens_hsa000613.15144686
3Nitrogen metabolism_Homo sapiens_hsa009102.91439135
4Protein digestion and absorption_Homo sapiens_hsa049742.80510136
5Basal cell carcinoma_Homo sapiens_hsa052172.33362794
6Focal adhesion_Homo sapiens_hsa045102.08795400
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.01168268
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.83656961
9Hippo signaling pathway_Homo sapiens_hsa043901.75157279
10Proteoglycans in cancer_Homo sapiens_hsa052051.74997765
11Hedgehog signaling pathway_Homo sapiens_hsa043401.56956767
12Fatty acid metabolism_Homo sapiens_hsa012121.56454926
13Adherens junction_Homo sapiens_hsa045201.51411843
14AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.50751025
15Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.50393656
16Pancreatic secretion_Homo sapiens_hsa049721.49107173
17Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.43965636
18Bladder cancer_Homo sapiens_hsa052191.38752990
19Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.35078748
20Dilated cardiomyopathy_Homo sapiens_hsa054141.35033945
21TGF-beta signaling pathway_Homo sapiens_hsa043501.33758342
22Fatty acid degradation_Homo sapiens_hsa000711.30423826
23Amoebiasis_Homo sapiens_hsa051461.29365258
24Malaria_Homo sapiens_hsa051441.28434282
25Melanogenesis_Homo sapiens_hsa049161.28222765
26Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.28179435
27Wnt signaling pathway_Homo sapiens_hsa043101.26528157
28Tight junction_Homo sapiens_hsa045301.20813433
29Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.17936938
30Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.13437258
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.11661329
32Melanoma_Homo sapiens_hsa052181.06834134
33Small cell lung cancer_Homo sapiens_hsa052221.06824894
34Axon guidance_Homo sapiens_hsa043601.04964738
35Vibrio cholerae infection_Homo sapiens_hsa051101.03509097
36Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02727662
37Leukocyte transendothelial migration_Homo sapiens_hsa046701.00592939
38Gastric acid secretion_Homo sapiens_hsa049711.00521380
39Glioma_Homo sapiens_hsa052141.00054716
40PPAR signaling pathway_Homo sapiens_hsa033200.99908142
41Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.99354487
42Vitamin B6 metabolism_Homo sapiens_hsa007500.97416554
43PI3K-Akt signaling pathway_Homo sapiens_hsa041510.95138751
44Cocaine addiction_Homo sapiens_hsa050300.94990402
45Rap1 signaling pathway_Homo sapiens_hsa040150.94702078
46Long-term potentiation_Homo sapiens_hsa047200.93443727
47Dorso-ventral axis formation_Homo sapiens_hsa043200.92067360
48Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90137825
49Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.89450869
50Salivary secretion_Homo sapiens_hsa049700.88855488
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.82594847
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81881424
53Neurotrophin signaling pathway_Homo sapiens_hsa047220.79981226
54Pathways in cancer_Homo sapiens_hsa052000.78869597
55MicroRNAs in cancer_Homo sapiens_hsa052060.78706708
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.77323944
57Complement and coagulation cascades_Homo sapiens_hsa046100.77210752
58Chronic myeloid leukemia_Homo sapiens_hsa052200.76784214
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.76750960
60Estrogen signaling pathway_Homo sapiens_hsa049150.76613717
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.75889261
62Bile secretion_Homo sapiens_hsa049760.75504939
63Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75421275
64Insulin secretion_Homo sapiens_hsa049110.74353045
65VEGF signaling pathway_Homo sapiens_hsa043700.74183320
66Endometrial cancer_Homo sapiens_hsa052130.74022298
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.73570758
68Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73272797
69GnRH signaling pathway_Homo sapiens_hsa049120.72377169
70Thyroid hormone synthesis_Homo sapiens_hsa049180.72044131
71Endocytosis_Homo sapiens_hsa041440.71064665
72Central carbon metabolism in cancer_Homo sapiens_hsa052300.70927769
73Synaptic vesicle cycle_Homo sapiens_hsa047210.70338252
74Glutamatergic synapse_Homo sapiens_hsa047240.70118556
75Gap junction_Homo sapiens_hsa045400.68956541
76Cholinergic synapse_Homo sapiens_hsa047250.68619388
77Pancreatic cancer_Homo sapiens_hsa052120.68037752
78Circadian rhythm_Homo sapiens_hsa047100.65600836
79Colorectal cancer_Homo sapiens_hsa052100.64152098
80Insulin resistance_Homo sapiens_hsa049310.64103861
81Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.63950688
82Prostate cancer_Homo sapiens_hsa052150.63311964
83cAMP signaling pathway_Homo sapiens_hsa040240.63196993
84GABAergic synapse_Homo sapiens_hsa047270.62389489
85Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.61029468
86mTOR signaling pathway_Homo sapiens_hsa041500.60657684
87Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60568515
88Morphine addiction_Homo sapiens_hsa050320.60490553
89AMPK signaling pathway_Homo sapiens_hsa041520.59554237
90Choline metabolism in cancer_Homo sapiens_hsa052310.59298125
91Thyroid cancer_Homo sapiens_hsa052160.59232035
92Non-small cell lung cancer_Homo sapiens_hsa052230.58709843
93Circadian entrainment_Homo sapiens_hsa047130.58158783
94Dopaminergic synapse_Homo sapiens_hsa047280.57435394
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56720127
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.56395075
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55837281
98Renin secretion_Homo sapiens_hsa049240.53832690
99Toxoplasmosis_Homo sapiens_hsa051450.53722454
100Ras signaling pathway_Homo sapiens_hsa040140.53027685
101Lysine degradation_Homo sapiens_hsa003100.52949381
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52596272
103Glycerolipid metabolism_Homo sapiens_hsa005610.52486956
104Propanoate metabolism_Homo sapiens_hsa006400.52354881
105Inositol phosphate metabolism_Homo sapiens_hsa005620.51197143
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51053689
107Viral myocarditis_Homo sapiens_hsa054160.50713968
108Biosynthesis of amino acids_Homo sapiens_hsa012300.50693630
109Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50579039
110Mineral absorption_Homo sapiens_hsa049780.50046967
111N-Glycan biosynthesis_Homo sapiens_hsa005100.49986735
112TNF signaling pathway_Homo sapiens_hsa046680.48977914
113Glucagon signaling pathway_Homo sapiens_hsa049220.48779127
114ErbB signaling pathway_Homo sapiens_hsa040120.48624863
115Renal cell carcinoma_Homo sapiens_hsa052110.48356889
116Notch signaling pathway_Homo sapiens_hsa043300.47865729
117Steroid biosynthesis_Homo sapiens_hsa001000.46206443
118Nicotine addiction_Homo sapiens_hsa050330.45449568
119Calcium signaling pathway_Homo sapiens_hsa040200.44953700
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.44486208
121Amphetamine addiction_Homo sapiens_hsa050310.42428078
122Renin-angiotensin system_Homo sapiens_hsa046140.41195940
123Prion diseases_Homo sapiens_hsa050200.39630003
124Glycosaminoglycan degradation_Homo sapiens_hsa005310.37093465
125Oxytocin signaling pathway_Homo sapiens_hsa049210.36960941

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