Rank | Gene Set | Z-score |
---|---|---|
1 | cellular ketone body metabolic process (GO:0046950) | 4.73688743 |
2 | glycerophospholipid catabolic process (GO:0046475) | 4.60827012 |
3 | detection of calcium ion (GO:0005513) | 4.55573274 |
4 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.39257065 |
5 | synaptic vesicle exocytosis (GO:0016079) | 4.35295416 |
6 | neuron cell-cell adhesion (GO:0007158) | 4.33552536 |
7 | inositol phosphate catabolic process (GO:0071545) | 4.32655808 |
8 | ketone body metabolic process (GO:1902224) | 4.17918506 |
9 | epithelial cell fate commitment (GO:0072148) | 4.13155024 |
10 | negative regulation of execution phase of apoptosis (GO:1900118) | 4.05632559 |
11 | inositol phosphate dephosphorylation (GO:0046855) | 4.04737881 |
12 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 4.04737881 |
13 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.04072473 |
14 | positive regulation of insulin secretion (GO:0032024) | 4.03168225 |
15 | protein maturation by protein folding (GO:0022417) | 4.02124134 |
16 | regulation of glucokinase activity (GO:0033131) | 4.01850122 |
17 | regulation of hexokinase activity (GO:1903299) | 4.01850122 |
18 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.01028508 |
19 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.98526079 |
20 | neuronal action potential propagation (GO:0019227) | 3.94927957 |
21 | vocalization behavior (GO:0071625) | 3.92897760 |
22 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 3.88206249 |
23 | presynaptic membrane assembly (GO:0097105) | 3.83029150 |
24 | lactate metabolic process (GO:0006089) | 3.82555902 |
25 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.79270789 |
26 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.77226010 |
27 | positive regulation of glycolytic process (GO:0045821) | 3.66107773 |
28 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.65549478 |
29 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.64766021 |
30 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.64766021 |
31 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.60703126 |
32 | positive regulation of peptide hormone secretion (GO:0090277) | 3.57850514 |
33 | COPI coating of Golgi vesicle (GO:0048205) | 3.55121907 |
34 | Golgi transport vesicle coating (GO:0048200) | 3.55121907 |
35 | signal peptide processing (GO:0006465) | 3.54307844 |
36 | regulation of synaptic vesicle transport (GO:1902803) | 3.52835802 |
37 | respiratory chain complex IV assembly (GO:0008535) | 3.51257347 |
38 | presynaptic membrane organization (GO:0097090) | 3.49704846 |
39 | protein localization to synapse (GO:0035418) | 3.48492256 |
40 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.48472407 |
41 | positive regulation of peptide secretion (GO:0002793) | 3.45861640 |
42 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.43792522 |
43 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.43331573 |
44 | nitric oxide mediated signal transduction (GO:0007263) | 3.42300112 |
45 | auditory receptor cell differentiation (GO:0042491) | 3.41769473 |
46 | polyol catabolic process (GO:0046174) | 3.41169039 |
47 | glandular epithelial cell differentiation (GO:0002067) | 3.40274444 |
48 | glutamate secretion (GO:0014047) | 3.37016069 |
49 | positive regulation of gluconeogenesis (GO:0045722) | 3.35692517 |
50 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.35106869 |
51 | insulin secretion (GO:0030073) | 3.33816904 |
52 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.32575525 |
53 | neuron-neuron synaptic transmission (GO:0007270) | 3.31158821 |
54 | neurotransmitter secretion (GO:0007269) | 3.30366663 |
55 | regulation of vesicle fusion (GO:0031338) | 3.29662140 |
56 | dopamine biosynthetic process (GO:0042416) | 3.27758489 |
57 | cytochrome complex assembly (GO:0017004) | 3.25046183 |
58 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.24616575 |
59 | negative regulation of hormone biosynthetic process (GO:0032353) | 3.24380490 |
60 | transferrin transport (GO:0033572) | 3.21804514 |
61 | macroautophagy (GO:0016236) | 3.21033268 |
62 | nitric oxide biosynthetic process (GO:0006809) | 3.20036240 |
63 | peptide hormone secretion (GO:0030072) | 3.19367074 |
64 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.17305176 |
65 | ATP synthesis coupled proton transport (GO:0015986) | 3.15614235 |
66 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.15614235 |
67 | neuron recognition (GO:0008038) | 3.12161491 |
68 | glutamate receptor signaling pathway (GO:0007215) | 3.11084051 |
69 | regulation of dopamine metabolic process (GO:0042053) | 3.11029916 |
70 | regulation of catecholamine metabolic process (GO:0042069) | 3.11029916 |
71 | positive regulation of macroautophagy (GO:0016239) | 3.09865288 |
72 | postsynaptic membrane organization (GO:0001941) | 3.09849867 |
73 | peptide secretion (GO:0002790) | 3.08404487 |
74 | synaptic transmission, glutamatergic (GO:0035249) | 3.02227114 |
75 | long-term synaptic potentiation (GO:0060291) | 3.02065212 |
76 | trivalent inorganic cation transport (GO:0072512) | 3.01651432 |
77 | ferric iron transport (GO:0015682) | 3.01651432 |
78 | positive regulation of response to nutrient levels (GO:0032109) | 3.00856372 |
79 | positive regulation of response to extracellular stimulus (GO:0032106) | 3.00856372 |
80 | regulation of neurotransmitter uptake (GO:0051580) | 2.99442552 |
81 | ER overload response (GO:0006983) | 2.98256033 |
82 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.96536630 |
83 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.95307484 |
84 | * peptide hormone processing (GO:0016486) | 2.94757513 |
85 | locomotory exploration behavior (GO:0035641) | 2.92617075 |
86 | zinc ion homeostasis (GO:0055069) | 2.92434881 |
87 | neurotransmitter transport (GO:0006836) | 2.92113412 |
88 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.91878518 |
89 | startle response (GO:0001964) | 2.91223821 |
90 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 2.90488287 |
91 | positive regulation of calcium ion import (GO:0090280) | 2.90325119 |
92 | regulation of peptide secretion (GO:0002791) | 2.89246892 |
93 | synaptic vesicle maturation (GO:0016188) | 2.88132653 |
94 | regulation of autophagic vacuole assembly (GO:2000785) | 2.87970977 |
95 | L-phenylalanine catabolic process (GO:0006559) | 2.86965875 |
96 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.86965875 |
97 | innervation (GO:0060384) | 2.85655357 |
98 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.83137777 |
99 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.83042822 |
100 | proline transport (GO:0015824) | 2.82896699 |
101 | endocrine pancreas development (GO:0031018) | 2.82646651 |
102 | positive regulation of exocytosis (GO:0045921) | 2.82513343 |
103 | positive regulation of vesicle fusion (GO:0031340) | 2.82244213 |
104 | regulation of insulin secretion (GO:0050796) | 2.81922005 |
105 | regulation of oxidative phosphorylation (GO:0002082) | 2.80899202 |
106 | negative regulation of protein oligomerization (GO:0032460) | 2.80429819 |
107 | synaptic vesicle endocytosis (GO:0048488) | 2.80102622 |
108 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.79692182 |
109 | exploration behavior (GO:0035640) | 2.79540498 |
110 | response to histamine (GO:0034776) | 2.79399024 |
111 | regulation of glutamate secretion (GO:0014048) | 2.79268970 |
112 | establishment of synaptic vesicle localization (GO:0097480) | 2.78514798 |
113 | synaptic vesicle transport (GO:0048489) | 2.78514798 |
114 | activation of protein kinase A activity (GO:0034199) | 2.78270045 |
115 | positive regulation of synapse assembly (GO:0051965) | 2.77757749 |
116 | positive regulation of meiosis (GO:0045836) | 2.77459459 |
117 | positive regulation of neurotransmitter transport (GO:0051590) | 2.77047433 |
118 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.76015770 |
119 | serotonin metabolic process (GO:0042428) | 2.75714720 |
120 | negative regulation of hormone metabolic process (GO:0032351) | 2.74832870 |
121 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.73470312 |
122 | neuromuscular process controlling posture (GO:0050884) | 2.72944353 |
123 | negative regulation of amine transport (GO:0051953) | 2.72875062 |
124 | protein targeting to Golgi (GO:0000042) | 2.72679657 |
125 | protein localization to Golgi apparatus (GO:0034067) | 2.72339828 |
126 | regulation of postsynaptic membrane potential (GO:0060078) | 2.71362428 |
127 | alanine transport (GO:0032328) | 2.70665350 |
128 | respiratory electron transport chain (GO:0022904) | 2.70349094 |
129 | regulation of exocytosis (GO:0017157) | 2.70321806 |
130 | kidney morphogenesis (GO:0060993) | 2.70076809 |
131 | positive regulation of hormone secretion (GO:0046887) | 2.69297394 |
132 | synaptic transmission, dopaminergic (GO:0001963) | 2.68697445 |
133 | positive regulation of membrane potential (GO:0045838) | 2.68050787 |
134 | negative regulation of neurotransmitter transport (GO:0051589) | 2.67872889 |
135 | behavioral response to cocaine (GO:0048148) | 2.67023544 |
136 | electron transport chain (GO:0022900) | 2.66436432 |
137 | protein localization to cilium (GO:0061512) | 2.65689858 |
138 | dendritic spine morphogenesis (GO:0060997) | 2.65524457 |
139 | type B pancreatic cell development (GO:0003323) | 2.65033031 |
140 | calcium ion import (GO:0070509) | 2.64749184 |
141 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.63401884 |
142 | chemosensory behavior (GO:0007635) | 2.63383899 |
143 | dentate gyrus development (GO:0021542) | 2.63378457 |
144 | L-phenylalanine metabolic process (GO:0006558) | 2.63137365 |
145 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.63137365 |
146 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.62583785 |
147 | nephron epithelium morphogenesis (GO:0072088) | 2.62528692 |
148 | nephron tubule morphogenesis (GO:0072078) | 2.62528692 |
149 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.62488391 |
150 | calcium ion-dependent exocytosis (GO:0017156) | 2.62280110 |
151 | transmission of nerve impulse (GO:0019226) | 2.62258394 |
152 | negative regulation of catecholamine secretion (GO:0033604) | 2.61699643 |
153 | cellular zinc ion homeostasis (GO:0006882) | 2.60907661 |
154 | cellular response to glucagon stimulus (GO:0071377) | 2.60867424 |
155 | peptide transport (GO:0015833) | 2.60442037 |
156 | renal tubule morphogenesis (GO:0061333) | 2.60105548 |
157 | regulation of vacuole organization (GO:0044088) | 2.60083053 |
158 | striatum development (GO:0021756) | 2.59918054 |
159 | regulation of energy homeostasis (GO:2000505) | 2.58823891 |
160 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.58602206 |
161 | mating behavior (GO:0007617) | 2.58218711 |
162 | regulation of neurotransmitter levels (GO:0001505) | 2.57693180 |
163 | positive regulation of amino acid transport (GO:0051957) | 2.57544175 |
164 | regulation of peptide hormone secretion (GO:0090276) | 2.57067929 |
165 | regulation of neurotransmitter secretion (GO:0046928) | 2.56717528 |
166 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.56666986 |
167 | brain morphogenesis (GO:0048854) | 2.56065863 |
168 | adult feeding behavior (GO:0008343) | 2.55674533 |
169 | positive regulation of meiotic cell cycle (GO:0051446) | 2.55495935 |
170 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.53654056 |
171 | intra-Golgi vesicle-mediated transport (GO:0006891) | 2.53454330 |
172 | negative regulation of neurological system process (GO:0031645) | 2.53229061 |
173 | establishment of protein localization to Golgi (GO:0072600) | 2.53066425 |
174 | regulation of protein glycosylation (GO:0060049) | 2.52402675 |
175 | * regulation of hormone secretion (GO:0046883) | 2.51568440 |
176 | phenylpropanoid metabolic process (GO:0009698) | 2.48271928 |
177 | retinol metabolic process (GO:0042572) | 2.48068939 |
178 | hormone secretion (GO:0046879) | 2.48056066 |
179 | protein complex biogenesis (GO:0070271) | 2.46528602 |
180 | astrocyte differentiation (GO:0048708) | 2.45516193 |
181 | cardiac left ventricle morphogenesis (GO:0003214) | 2.44060852 |
182 | nodal signaling pathway (GO:0038092) | 2.43807631 |
183 | axoneme assembly (GO:0035082) | 2.43459433 |
184 | regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178) | 2.43415264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.40746581 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.98369528 |
3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.38106742 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.86137842 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.69968551 |
6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.66812388 |
7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.58288990 |
8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.43180964 |
9 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.37938481 |
10 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.36256641 |
11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.32826747 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.27941750 |
13 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.27921371 |
14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.27144456 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.25683560 |
16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.20682601 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.16832564 |
18 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.16383453 |
19 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.13193051 |
20 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.13007838 |
21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.07741735 |
22 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.04198484 |
23 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.04198484 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.03566813 |
25 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.02896262 |
26 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.96164847 |
27 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.95281284 |
28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.94763294 |
29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.92224109 |
30 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.89940413 |
31 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.87898112 |
32 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.86932351 |
33 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.86551533 |
34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.85627855 |
35 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.84201361 |
36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.78296715 |
37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.75822565 |
38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.74811960 |
39 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.71541240 |
40 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.67640880 |
41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67097251 |
42 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.66457951 |
43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.62084629 |
44 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.59329354 |
45 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.58728754 |
46 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.57017312 |
47 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.56420617 |
48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.53072659 |
49 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.51065317 |
50 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.45520917 |
51 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.45414945 |
52 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.39783752 |
53 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.39496251 |
54 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.38084730 |
55 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35923339 |
56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.35196724 |
57 | STAT3_23295773_ChIP-Seq_U87_Human | 1.33072481 |
58 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.31658886 |
59 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.31439004 |
60 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.29945023 |
61 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.28099922 |
62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.27418201 |
63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26592792 |
64 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.24856298 |
65 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.24742251 |
66 | AR_25329375_ChIP-Seq_VCAP_Human | 1.23374725 |
67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.21234706 |
68 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.19894320 |
69 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.18821870 |
70 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.18760468 |
71 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.18349042 |
72 | TCF4_23295773_ChIP-Seq_U87_Human | 1.18271342 |
73 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.18003820 |
74 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.17786558 |
75 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.17733017 |
76 | EWS_26573619_Chip-Seq_HEK293_Human | 1.17178658 |
77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.16571774 |
78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.16571774 |
79 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.15998900 |
80 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.15947265 |
81 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.15930044 |
82 | * FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15810628 |
83 | * FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15810628 |
84 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15298241 |
85 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.13752241 |
86 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.13213965 |
87 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13157167 |
88 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12771191 |
89 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.12267625 |
90 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.11503140 |
91 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.10545523 |
92 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.10178979 |
93 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.08829939 |
94 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.08545739 |
95 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.08005102 |
96 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.07429681 |
97 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.07341829 |
98 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.07261257 |
99 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.06656697 |
100 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.06466647 |
101 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.06266136 |
102 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.04529038 |
103 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.04301993 |
104 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03411286 |
105 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.02772535 |
106 | JUN_21703547_ChIP-Seq_K562_Human | 1.02057375 |
107 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.02043795 |
108 | * CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.01933891 |
109 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01550237 |
110 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.00931630 |
111 | * NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00770328 |
112 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.99831253 |
113 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99798402 |
114 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.99027103 |
115 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.97839588 |
116 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.97660236 |
117 | AR_20517297_ChIP-Seq_VCAP_Human | 0.97590407 |
118 | AR_19668381_ChIP-Seq_PC3_Human | 0.97557903 |
119 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.97396997 |
120 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.97306484 |
121 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.96942257 |
122 | KDM2B_26808549_Chip-Seq_REH_Human | 0.95193805 |
123 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.94472266 |
124 | * OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94263216 |
125 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.93965867 |
126 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93960795 |
127 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.93730028 |
128 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.93250916 |
129 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.91950601 |
130 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.91913571 |
131 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91696684 |
132 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91471210 |
133 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.90860651 |
134 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90461304 |
135 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.90456589 |
136 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.87154646 |
137 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.87064958 |
138 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87064958 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 4.42217564 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.65704280 |
3 | MP0004270_analgesia | 3.23392841 |
4 | MP0003635_abnormal_synaptic_transmissio | 3.22866281 |
5 | MP0010234_abnormal_vibrissa_follicle | 3.10701737 |
6 | MP0002909_abnormal_adrenal_gland | 2.87290730 |
7 | MP0010386_abnormal_urinary_bladder | 2.81064110 |
8 | MP0009745_abnormal_behavioral_response | 2.79905704 |
9 | MP0009780_abnormal_chondrocyte_physiolo | 2.71961621 |
10 | MP0002063_abnormal_learning/memory/cond | 2.61026676 |
11 | MP0008877_abnormal_DNA_methylation | 2.57941230 |
12 | MP0002139_abnormal_hepatobiliary_system | 2.55046992 |
13 | MP0002572_abnormal_emotion/affect_behav | 2.54795970 |
14 | * MP0002064_seizures | 2.53259647 |
15 | MP0001968_abnormal_touch/_nociception | 2.50403921 |
16 | MP0002734_abnormal_mechanical_nocicepti | 2.39855556 |
17 | MP0002272_abnormal_nervous_system | 2.37686276 |
18 | MP0009046_muscle_twitch | 2.36664680 |
19 | MP0005645_abnormal_hypothalamus_physiol | 2.33785970 |
20 | MP0006276_abnormal_autonomic_nervous | 2.32046353 |
21 | MP0001529_abnormal_vocalization | 2.28797789 |
22 | MP0004043_abnormal_pH_regulation | 2.25353162 |
23 | MP0003122_maternal_imprinting | 2.20814361 |
24 | MP0001501_abnormal_sleep_pattern | 2.18462233 |
25 | MP0002736_abnormal_nociception_after | 2.09769262 |
26 | MP0002733_abnormal_thermal_nociception | 2.05543782 |
27 | MP0005646_abnormal_pituitary_gland | 2.05189561 |
28 | MP0003283_abnormal_digestive_organ | 2.00164212 |
29 | MP0003183_abnormal_peptide_metabolism | 1.99418092 |
30 | MP0001440_abnormal_grooming_behavior | 1.99000542 |
31 | MP0002735_abnormal_chemical_nociception | 1.96934179 |
32 | MP0001486_abnormal_startle_reflex | 1.90349372 |
33 | MP0001970_abnormal_pain_threshold | 1.90331220 |
34 | MP0002693_abnormal_pancreas_physiology | 1.88397522 |
35 | MP0002254_reproductive_system_inflammat | 1.86945213 |
36 | MP0002822_catalepsy | 1.82869002 |
37 | MP0002067_abnormal_sensory_capabilities | 1.79907044 |
38 | MP0006072_abnormal_retinal_apoptosis | 1.74859220 |
39 | MP0010329_abnormal_lipoprotein_level | 1.74238331 |
40 | MP0004019_abnormal_vitamin_homeostasis | 1.70971125 |
41 | MP0001984_abnormal_olfaction | 1.70692042 |
42 | MP0002184_abnormal_innervation | 1.70342840 |
43 | MP0002638_abnormal_pupillary_reflex | 1.69568858 |
44 | MP0001188_hyperpigmentation | 1.67866344 |
45 | MP0001905_abnormal_dopamine_level | 1.66507996 |
46 | MP0001756_abnormal_urination | 1.65509231 |
47 | MP0003123_paternal_imprinting | 1.65378972 |
48 | MP0003172_abnormal_lysosome_physiology | 1.64415058 |
49 | MP0003195_calcinosis | 1.64366045 |
50 | MP0002557_abnormal_social/conspecific_i | 1.63618469 |
51 | MP0002876_abnormal_thyroid_physiology | 1.62018926 |
52 | MP0005332_abnormal_amino_acid | 1.61770698 |
53 | MP0003787_abnormal_imprinting | 1.59205084 |
54 | MP0001502_abnormal_circadian_rhythm | 1.58994605 |
55 | MP0005386_behavior/neurological_phenoty | 1.57872723 |
56 | MP0004924_abnormal_behavior | 1.57872723 |
57 | MP0005423_abnormal_somatic_nervous | 1.55591426 |
58 | * MP0000013_abnormal_adipose_tissue | 1.55062259 |
59 | * MP0001944_abnormal_pancreas_morphology | 1.54650257 |
60 | MP0003329_amyloid_beta_deposits | 1.52456109 |
61 | MP0003879_abnormal_hair_cell | 1.46060944 |
62 | MP0001986_abnormal_taste_sensitivity | 1.40027750 |
63 | MP0000678_abnormal_parathyroid_gland | 1.39590253 |
64 | MP0000955_abnormal_spinal_cord | 1.33549282 |
65 | MP0005084_abnormal_gallbladder_morpholo | 1.32819711 |
66 | * MP0005379_endocrine/exocrine_gland_phen | 1.28931769 |
67 | MP0000778_abnormal_nervous_system | 1.28099212 |
68 | MP0002928_abnormal_bile_duct | 1.25606950 |
69 | MP0002877_abnormal_melanocyte_morpholog | 1.23257357 |
70 | MP0004133_heterotaxia | 1.21570502 |
71 | MP0002066_abnormal_motor_capabilities/c | 1.20531773 |
72 | MP0000427_abnormal_hair_cycle | 1.19313922 |
73 | MP0004142_abnormal_muscle_tone | 1.18715904 |
74 | MP0004811_abnormal_neuron_physiology | 1.17912817 |
75 | MP0008569_lethality_at_weaning | 1.17592681 |
76 | MP0005365_abnormal_bile_salt | 1.16613630 |
77 | MP0003011_delayed_dark_adaptation | 1.15867689 |
78 | MP0002938_white_spotting | 1.14937403 |
79 | MP0002882_abnormal_neuron_morphology | 1.14581323 |
80 | MP0004145_abnormal_muscle_electrophysio | 1.14459476 |
81 | MP0010678_abnormal_skin_adnexa | 1.12890801 |
82 | MP0005551_abnormal_eye_electrophysiolog | 1.11797390 |
83 | MP0000569_abnormal_digit_pigmentation | 1.10671131 |
84 | * MP0002078_abnormal_glucose_homeostasis | 1.09814058 |
85 | * MP0005535_abnormal_body_temperature | 1.07749231 |
86 | MP0005075_abnormal_melanosome_morpholog | 1.05844687 |
87 | * MP0005636_abnormal_mineral_homeostasis | 1.04546222 |
88 | MP0003633_abnormal_nervous_system | 1.02696782 |
89 | MP0002229_neurodegeneration | 1.01813523 |
90 | * MP0000631_abnormal_neuroendocrine_gland | 1.01390377 |
91 | MP0005174_abnormal_tail_pigmentation | 0.98967684 |
92 | MP0001664_abnormal_digestion | 0.97861889 |
93 | MP0002118_abnormal_lipid_homeostasis | 0.96978911 |
94 | * MP0002069_abnormal_eating/drinking_beha | 0.94638331 |
95 | * MP0001765_abnormal_ion_homeostasis | 0.92354953 |
96 | MP0006036_abnormal_mitochondrial_physio | 0.91317279 |
97 | MP0004858_abnormal_nervous_system | 0.89725492 |
98 | MP0000516_abnormal_urinary_system | 0.89705858 |
99 | MP0005367_renal/urinary_system_phenotyp | 0.89705858 |
100 | MP0002234_abnormal_pharynx_morphology | 0.88258716 |
101 | MP0008872_abnormal_physiological_respon | 0.87411965 |
102 | MP0004085_abnormal_heartbeat | 0.84797092 |
103 | MP0005253_abnormal_eye_physiology | 0.83918840 |
104 | * MP0003953_abnormal_hormone_level | 0.81468503 |
105 | MP0005409_darkened_coat_color | 0.81213555 |
106 | MP0003631_nervous_system_phenotype | 0.81049099 |
107 | MP0001963_abnormal_hearing_physiology | 0.80637650 |
108 | MP0004742_abnormal_vestibular_system | 0.80291843 |
109 | * MP0002837_dystrophic_cardiac_calcinosis | 0.80026155 |
110 | MP0005389_reproductive_system_phenotype | 0.78793318 |
111 | MP0006292_abnormal_olfactory_placode | 0.78474966 |
112 | MP0004885_abnormal_endolymph | 0.78375155 |
113 | MP0000538_abnormal_urinary_bladder | 0.77523322 |
114 | * MP0002152_abnormal_brain_morphology | 0.77373649 |
115 | MP0003634_abnormal_glial_cell | 0.75884280 |
116 | MP0005452_abnormal_adipose_tissue | 0.74909929 |
117 | MP0005248_abnormal_Harderian_gland | 0.74837440 |
118 | MP0003121_genomic_imprinting | 0.71593336 |
119 | MP0002102_abnormal_ear_morphology | 0.71474223 |
120 | MP0000462_abnormal_digestive_system | 0.70518849 |
121 | MP0000015_abnormal_ear_pigmentation | 0.70342503 |
122 | MP0005220_abnormal_exocrine_pancreas | 0.69899479 |
123 | MP0002751_abnormal_autonomic_nervous | 0.68097607 |
124 | MP0009643_abnormal_urine_homeostasis | 0.67880319 |
125 | MP0002160_abnormal_reproductive_system | 0.67733043 |
126 | MP0005499_abnormal_olfactory_system | 0.67391633 |
127 | MP0005394_taste/olfaction_phenotype | 0.67391633 |
128 | MP0000230_abnormal_systemic_arterial | 0.66909846 |
129 | MP0002090_abnormal_vision | 0.66599208 |
130 | MP0003959_abnormal_lean_body | 0.66136438 |
131 | MP0001485_abnormal_pinna_reflex | 0.65830415 |
132 | MP0005448_abnormal_energy_balance | 0.65170079 |
133 | MP0002752_abnormal_somatic_nervous | 0.63799496 |
134 | MP0008961_abnormal_basal_metabolism | 0.63345661 |
135 | MP0004215_abnormal_myocardial_fiber | 0.62198624 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 6.01993357 |
2 | Visual hallucinations (HP:0002367) | 4.72795457 |
3 | Atonic seizures (HP:0010819) | 4.50764093 |
4 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 4.45008174 |
5 | Epileptic encephalopathy (HP:0200134) | 3.94644859 |
6 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.87106368 |
7 | Hyperinsulinemic hypoglycemia (HP:0000825) | 3.84770640 |
8 | Focal seizures (HP:0007359) | 3.80624761 |
9 | Absence seizures (HP:0002121) | 3.78249941 |
10 | Acute necrotizing encephalopathy (HP:0006965) | 3.65749027 |
11 | Intestinal atresia (HP:0011100) | 3.49101407 |
12 | Dialeptic seizures (HP:0011146) | 3.43152809 |
13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.39184952 |
14 | Febrile seizures (HP:0002373) | 3.34589758 |
15 | Double outlet right ventricle (HP:0001719) | 3.29541394 |
16 | Congenital malformation of the right heart (HP:0011723) | 3.29541394 |
17 | Pheochromocytoma (HP:0002666) | 3.29021600 |
18 | Hyperventilation (HP:0002883) | 3.27730978 |
19 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 3.25519462 |
20 | Progressive macrocephaly (HP:0004481) | 3.23519301 |
21 | Symptomatic seizures (HP:0011145) | 3.22741306 |
22 | Epileptiform EEG discharges (HP:0011182) | 3.19217626 |
23 | Hypoglycemic seizures (HP:0002173) | 3.18688462 |
24 | Ketosis (HP:0001946) | 3.12237292 |
25 | EEG with generalized epileptiform discharges (HP:0011198) | 3.08360234 |
26 | Abnormality of vitamin B metabolism (HP:0004340) | 3.07036997 |
27 | Agitation (HP:0000713) | 3.06277868 |
28 | Neuroendocrine neoplasm (HP:0100634) | 3.05635440 |
29 | Generalized tonic-clonic seizures (HP:0002069) | 3.04625068 |
30 | Hypothermia (HP:0002045) | 2.97068098 |
31 | Enlarged penis (HP:0000040) | 2.96821542 |
32 | Hypsarrhythmia (HP:0002521) | 2.88087368 |
33 | Limb dystonia (HP:0002451) | 2.87284693 |
34 | Acute encephalopathy (HP:0006846) | 2.83228390 |
35 | Anxiety (HP:0000739) | 2.81398036 |
36 | Mitochondrial inheritance (HP:0001427) | 2.81118423 |
37 | Myokymia (HP:0002411) | 2.78137227 |
38 | Cerebral inclusion bodies (HP:0100314) | 2.77929819 |
39 | Gait imbalance (HP:0002141) | 2.75891051 |
40 | Decreased circulating renin level (HP:0003351) | 2.74006447 |
41 | Increased CSF protein (HP:0002922) | 2.67988831 |
42 | Medial flaring of the eyebrow (HP:0010747) | 2.66790850 |
43 | Amblyopia (HP:0000646) | 2.63361552 |
44 | Hypomagnesemia (HP:0002917) | 2.60561643 |
45 | Congenital primary aphakia (HP:0007707) | 2.60264655 |
46 | Dysautonomia (HP:0002459) | 2.59737328 |
47 | Methylmalonic acidemia (HP:0002912) | 2.51424224 |
48 | Abnormality of vitamin metabolism (HP:0100508) | 2.48730856 |
49 | Neurofibrillary tangles (HP:0002185) | 2.46565278 |
50 | Progressive cerebellar ataxia (HP:0002073) | 2.44988321 |
51 | Truncal ataxia (HP:0002078) | 2.42758570 |
52 | Ketoacidosis (HP:0001993) | 2.40716813 |
53 | Nephrogenic diabetes insipidus (HP:0009806) | 2.40490240 |
54 | Pancreatic fibrosis (HP:0100732) | 2.38127619 |
55 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.34124169 |
56 | Polydipsia (HP:0001959) | 2.31883728 |
57 | Abnormal drinking behavior (HP:0030082) | 2.31883728 |
58 | Supranuclear gaze palsy (HP:0000605) | 2.30004048 |
59 | Retinal dysplasia (HP:0007973) | 2.29106931 |
60 | Abnormality of the renal cortex (HP:0011035) | 2.28955783 |
61 | Glycosuria (HP:0003076) | 2.26187499 |
62 | Abnormality of urine glucose concentration (HP:0011016) | 2.26187499 |
63 | Abnormal albumin level (HP:0012116) | 2.25078442 |
64 | Hypoalbuminemia (HP:0003073) | 2.25078442 |
65 | Failure to thrive in infancy (HP:0001531) | 2.24187145 |
66 | Hemiparesis (HP:0001269) | 2.23218771 |
67 | Drooling (HP:0002307) | 2.22118000 |
68 | Excessive salivation (HP:0003781) | 2.22118000 |
69 | Progressive neurologic deterioration (HP:0002344) | 2.21750110 |
70 | Type II lissencephaly (HP:0007260) | 2.20646673 |
71 | Tongue fasciculations (HP:0001308) | 2.20021703 |
72 | Depression (HP:0000716) | 2.19797929 |
73 | Increased CSF lactate (HP:0002490) | 2.19713328 |
74 | Pancreatic cysts (HP:0001737) | 2.17122245 |
75 | Proximal tubulopathy (HP:0000114) | 2.15597414 |
76 | Hypokinesia (HP:0002375) | 2.14565016 |
77 | Hematochezia (HP:0002573) | 2.14263032 |
78 | Hepatic necrosis (HP:0002605) | 2.14087570 |
79 | Conjunctival hamartoma (HP:0100780) | 2.13919828 |
80 | Nephronophthisis (HP:0000090) | 2.12982195 |
81 | Hyperglycemia (HP:0003074) | 2.11798184 |
82 | Prominent metopic ridge (HP:0005487) | 2.11293590 |
83 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.11184239 |
84 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.11184239 |
85 | Hyperphosphatemia (HP:0002905) | 2.10973465 |
86 | Vascular calcification (HP:0004934) | 2.10214572 |
87 | Genital tract atresia (HP:0001827) | 2.09839338 |
88 | Vaginal atresia (HP:0000148) | 2.09389911 |
89 | Large for gestational age (HP:0001520) | 2.07527657 |
90 | Broad-based gait (HP:0002136) | 2.07415699 |
91 | Retinal atrophy (HP:0001105) | 2.06531132 |
92 | Testicular neoplasm (HP:0010788) | 2.05575635 |
93 | Hamartoma of the eye (HP:0010568) | 2.04789900 |
94 | Psychosis (HP:0000709) | 2.04549029 |
95 | Methylmalonic aciduria (HP:0012120) | 2.04002940 |
96 | Congenital sensorineural hearing impairment (HP:0008527) | 2.00478706 |
97 | Menstrual irregularities (HP:0000858) | 2.00451894 |
98 | Neoplasm of the adrenal cortex (HP:0100641) | 2.00132249 |
99 | Optic disc pallor (HP:0000543) | 2.00092963 |
100 | Sex reversal (HP:0012245) | 1.99979964 |
101 | Abnormal sex determination (HP:0012244) | 1.99979964 |
102 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.99741499 |
103 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.99741499 |
104 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.99741499 |
105 | Postural tremor (HP:0002174) | 1.97523400 |
106 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.97334377 |
107 | Abnormality of the metopic suture (HP:0005556) | 1.97279416 |
108 | Resting tremor (HP:0002322) | 1.96687811 |
109 | Furrowed tongue (HP:0000221) | 1.95893294 |
110 | Protruding tongue (HP:0010808) | 1.95751376 |
111 | Tubular atrophy (HP:0000092) | 1.94867820 |
112 | Aqueductal stenosis (HP:0002410) | 1.94146619 |
113 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.94067239 |
114 | Hypoplasia of the fovea (HP:0007750) | 1.94067239 |
115 | Blue irides (HP:0000635) | 1.92010979 |
116 | Abnormality of magnesium homeostasis (HP:0004921) | 1.90769725 |
117 | Restlessness (HP:0000711) | 1.90368193 |
118 | Mucopolysacchariduria (HP:0008155) | 1.90048710 |
119 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.90048710 |
120 | Unilateral renal agenesis (HP:0000122) | 1.89667074 |
121 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.89197332 |
122 | Delusions (HP:0000746) | 1.88950365 |
123 | Hypoglycemic coma (HP:0001325) | 1.88257821 |
124 | Molar tooth sign on MRI (HP:0002419) | 1.87534700 |
125 | Abnormality of midbrain morphology (HP:0002418) | 1.87534700 |
126 | Abnormal eating behavior (HP:0100738) | 1.87078501 |
127 | Hyperthyroidism (HP:0000836) | 1.86714835 |
128 | Progressive inability to walk (HP:0002505) | 1.86367485 |
129 | Renal cortical cysts (HP:0000803) | 1.85803256 |
130 | Diminished movement (HP:0002374) | 1.85758409 |
131 | Cortical visual impairment (HP:0100704) | 1.85700188 |
132 | Oligomenorrhea (HP:0000876) | 1.85272083 |
133 | Abnormal hair whorl (HP:0010721) | 1.84308321 |
134 | Orthostatic hypotension (HP:0001278) | 1.84206487 |
135 | Increased circulating renin level (HP:0000848) | 1.82797717 |
136 | Impaired smooth pursuit (HP:0007772) | 1.81732771 |
137 | Papilledema (HP:0001085) | 1.81375490 |
138 | Hepatocellular necrosis (HP:0001404) | 1.81250240 |
139 | Absent speech (HP:0001344) | 1.80945374 |
140 | Abnormality of renin-angiotensin system (HP:0000847) | 1.80927595 |
141 | Poor eye contact (HP:0000817) | 1.80745306 |
142 | Abnormal pancreas size (HP:0012094) | 1.80553086 |
143 | Hyperparathyroidism (HP:0000843) | 1.80425135 |
144 | True hermaphroditism (HP:0010459) | 1.80402473 |
145 | Abnormality of the renal medulla (HP:0100957) | 1.79142760 |
146 | Muscle fibrillation (HP:0010546) | 1.78366059 |
147 | Polyphagia (HP:0002591) | 1.78046400 |
148 | Late onset (HP:0003584) | 1.78013424 |
149 | 3-Methylglutaconic aciduria (HP:0003535) | 1.77687845 |
150 | Poor suck (HP:0002033) | 1.76203286 |
151 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.73403927 |
152 | Muscular hypotonia of the trunk (HP:0008936) | 1.72805498 |
153 | Hypokalemia (HP:0002900) | 1.72454312 |
154 | Dysmetria (HP:0001310) | 1.72209558 |
155 | Increased hepatocellular lipid droplets (HP:0006565) | 1.72034039 |
156 | Abnormality of binocular vision (HP:0011514) | 1.71840141 |
157 | Diplopia (HP:0000651) | 1.71840141 |
158 | Bradykinesia (HP:0002067) | 1.71171204 |
159 | Gaze-evoked nystagmus (HP:0000640) | 1.70970284 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 3.96817657 |
2 | FGFR2 | 3.37802526 |
3 | CASK | 3.37372662 |
4 | INSRR | 3.35329539 |
5 | EPHA4 | 3.08503170 |
6 | PHKG1 | 2.96406015 |
7 | PHKG2 | 2.96406015 |
8 | MAP3K4 | 2.93834349 |
9 | MAP2K7 | 2.81981365 |
10 | MAP3K12 | 2.68788936 |
11 | MST4 | 2.60018125 |
12 | MAP4K2 | 2.55598542 |
13 | MAPK15 | 2.54000855 |
14 | RIPK4 | 2.36737922 |
15 | PNCK | 2.27052381 |
16 | MAP3K9 | 2.23756909 |
17 | WNK3 | 2.21379784 |
18 | GRK1 | 2.12987643 |
19 | NTRK1 | 2.06181279 |
20 | ARAF | 2.03134870 |
21 | MAP2K6 | 2.02981933 |
22 | PINK1 | 1.88489208 |
23 | WNK4 | 1.82211064 |
24 | GRK5 | 1.82060987 |
25 | UHMK1 | 1.77859975 |
26 | NME1 | 1.76073564 |
27 | PLK2 | 1.73377385 |
28 | MAP2K4 | 1.72603766 |
29 | BMPR2 | 1.71844342 |
30 | MINK1 | 1.67623323 |
31 | MARK1 | 1.65193452 |
32 | PRKD3 | 1.64675800 |
33 | CAMKK2 | 1.63687420 |
34 | FGFR3 | 1.62880163 |
35 | PASK | 1.59405943 |
36 | MAP3K2 | 1.59226223 |
37 | FRK | 1.49928973 |
38 | DAPK2 | 1.43146042 |
39 | NLK | 1.42217689 |
40 | DAPK1 | 1.42135089 |
41 | CSNK1G1 | 1.33329843 |
42 | TRPM7 | 1.31073736 |
43 | AKT3 | 1.28180210 |
44 | STK3 | 1.23970201 |
45 | KSR2 | 1.22468021 |
46 | NTRK2 | 1.22000341 |
47 | ACVR1B | 1.21105837 |
48 | CDK5 | 1.20700623 |
49 | HIPK2 | 1.19901354 |
50 | CAMK2B | 1.19272398 |
51 | CAMK2A | 1.16597107 |
52 | STK24 | 1.14693557 |
53 | EPHA3 | 1.13040507 |
54 | STK38L | 1.10731313 |
55 | BRAF | 1.09779198 |
56 | PRKCG | 1.09144820 |
57 | TAOK3 | 1.08378590 |
58 | MAPK13 | 1.08160325 |
59 | GRK7 | 1.05266824 |
60 | PRKCE | 1.00974851 |
61 | CDK19 | 1.00905327 |
62 | PAK3 | 0.99100579 |
63 | ERBB3 | 0.96542317 |
64 | MAP3K1 | 0.95511353 |
65 | PAK6 | 0.93047684 |
66 | TAOK1 | 0.92174627 |
67 | CAMK2D | 0.92086494 |
68 | TNIK | 0.86995320 |
69 | OXSR1 | 0.86863117 |
70 | KSR1 | 0.86243283 |
71 | STK11 | 0.85226507 |
72 | MAP3K13 | 0.82672479 |
73 | MKNK2 | 0.80496421 |
74 | DYRK1A | 0.80126860 |
75 | ADRBK2 | 0.79516584 |
76 | BCR | 0.77088326 |
77 | PTK2B | 0.76965880 |
78 | SGK494 | 0.73940110 |
79 | SGK223 | 0.73940110 |
80 | TRIM28 | 0.72728271 |
81 | SIK2 | 0.72667673 |
82 | FES | 0.72558026 |
83 | YES1 | 0.72140142 |
84 | FGR | 0.71631846 |
85 | PIK3CG | 0.70417248 |
86 | FER | 0.70131174 |
87 | ADRBK1 | 0.69700074 |
88 | ZAK | 0.69211992 |
89 | TNK2 | 0.68075869 |
90 | PRKAA1 | 0.67585423 |
91 | STK16 | 0.67552744 |
92 | IRAK1 | 0.67416466 |
93 | CCNB1 | 0.65905766 |
94 | PRKCI | 0.65447611 |
95 | PRKCH | 0.64836875 |
96 | WNK1 | 0.64488699 |
97 | PRKAA2 | 0.64483515 |
98 | CAMKK1 | 0.63034497 |
99 | CSNK1G2 | 0.60907460 |
100 | LIMK1 | 0.60564561 |
101 | CAMK1G | 0.60018126 |
102 | CDC42BPA | 0.59452710 |
103 | CSNK1A1L | 0.58835501 |
104 | CAMK2G | 0.57274445 |
105 | BMPR1B | 0.55961872 |
106 | CDK14 | 0.54237771 |
107 | PRKACA | 0.53676476 |
108 | SGK1 | 0.52011566 |
109 | STK4 | 0.50985197 |
110 | RET | 0.50419796 |
111 | CDK18 | 0.49020425 |
112 | SGK2 | 0.46395959 |
113 | SIK3 | 0.45834196 |
114 | PLK3 | 0.45337701 |
115 | CDK15 | 0.45331855 |
116 | PRKD2 | 0.45202910 |
117 | MAP2K1 | 0.43830342 |
118 | MUSK | 0.41927385 |
119 | RAF1 | 0.40663789 |
120 | CSNK1D | 0.40097879 |
121 | PRKCZ | 0.39404749 |
122 | PRKG2 | 0.38828516 |
123 | SCYL2 | 0.37686099 |
124 | CDK11A | 0.37538797 |
125 | STK39 | 0.37078773 |
126 | PRKACB | 0.36359456 |
127 | GRK6 | 0.36022592 |
128 | CSNK1A1 | 0.35638002 |
129 | PRKCA | 0.35211183 |
130 | MAPKAPK5 | 0.34377566 |
131 | CDK3 | 0.32157524 |
132 | MYLK | 0.31550716 |
133 | GSK3A | 0.31305316 |
134 | RPS6KA3 | 0.30971512 |
135 | MAPK10 | 0.30726534 |
136 | CSNK1G3 | 0.30684196 |
137 | CSNK1E | 0.30617778 |
138 | CAMK1 | 0.30124143 |
139 | NUAK1 | 0.29753067 |
140 | PRKCB | 0.29542914 |
141 | PRKG1 | 0.28613981 |
142 | STK38 | 0.27767900 |
143 | EIF2AK3 | 0.27702778 |
144 | TLK1 | 0.24659996 |
145 | SGK3 | 0.24617595 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 3.62866411 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.11108323 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.97959493 |
4 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.84634509 |
5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.77542044 |
6 | Insulin secretion_Homo sapiens_hsa04911 | 2.74118502 |
7 | Protein export_Homo sapiens_hsa03060 | 2.70479593 |
8 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.49623296 |
9 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.43805949 |
10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.39614131 |
11 | GABAergic synapse_Homo sapiens_hsa04727 | 2.33827379 |
12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.26712648 |
13 | Long-term potentiation_Homo sapiens_hsa04720 | 2.25809170 |
14 | Taste transduction_Homo sapiens_hsa04742 | 2.19963725 |
15 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.17318610 |
16 | Circadian entrainment_Homo sapiens_hsa04713 | 2.14991546 |
17 | Morphine addiction_Homo sapiens_hsa05032 | 2.07873361 |
18 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.03939922 |
19 | Parkinsons disease_Homo sapiens_hsa05012 | 2.01395124 |
20 | Alzheimers disease_Homo sapiens_hsa05010 | 2.00763431 |
21 | Cocaine addiction_Homo sapiens_hsa05030 | 1.98504101 |
22 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.89688755 |
23 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.85540202 |
24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.72835611 |
25 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.72553058 |
26 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.68598875 |
27 | Olfactory transduction_Homo sapiens_hsa04740 | 1.68199024 |
28 | Renin secretion_Homo sapiens_hsa04924 | 1.66205601 |
29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.54605811 |
30 | Salivary secretion_Homo sapiens_hsa04970 | 1.54432754 |
31 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.54227586 |
32 | Long-term depression_Homo sapiens_hsa04730 | 1.48951626 |
33 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.48354923 |
34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.45766085 |
35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.43058630 |
36 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.42526805 |
37 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36922267 |
38 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.31909759 |
39 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.31637564 |
40 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.30441823 |
41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.28864746 |
42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.21632877 |
43 | Peroxisome_Homo sapiens_hsa04146 | 1.20469819 |
44 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.19280413 |
45 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.09388059 |
46 | Phototransduction_Homo sapiens_hsa04744 | 1.07548418 |
47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.06989605 |
48 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.06739628 |
49 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.04028743 |
50 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03534013 |
51 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.00526425 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.00092047 |
53 | Mineral absorption_Homo sapiens_hsa04978 | 0.98410392 |
54 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.94325692 |
55 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.93505686 |
56 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.93457697 |
57 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.92712433 |
58 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.91688262 |
59 | Gap junction_Homo sapiens_hsa04540 | 0.91063365 |
60 | ABC transporters_Homo sapiens_hsa02010 | 0.89988959 |
61 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.89468141 |
62 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.88153479 |
63 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.86672271 |
64 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.86516326 |
65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.85374600 |
66 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.84388468 |
67 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83746032 |
68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.82811255 |
69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.81875463 |
70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.81847123 |
71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79986539 |
72 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.78178110 |
73 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77596311 |
74 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76917440 |
75 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.76585085 |
76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75378649 |
77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.74123556 |
78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.72788673 |
79 | Melanogenesis_Homo sapiens_hsa04916 | 0.72608864 |
80 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72308110 |
81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70534901 |
82 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.69875709 |
83 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.69851160 |
84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.68399333 |
85 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.66119049 |
86 | Alcoholism_Homo sapiens_hsa05034 | 0.64254590 |
87 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.63949986 |
88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.63900631 |
89 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58690372 |
90 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.57851653 |
91 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57142217 |
92 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.55532663 |
93 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.54257437 |
94 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.54157384 |
95 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54069174 |
96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.53373999 |
97 | Prion diseases_Homo sapiens_hsa05020 | 0.52054620 |
98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.51676707 |
99 | Other glycan degradation_Homo sapiens_hsa00511 | 0.51184870 |
100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51095654 |
101 | Phagosome_Homo sapiens_hsa04145 | 0.51062714 |
102 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.49385440 |
103 | Axon guidance_Homo sapiens_hsa04360 | 0.45313235 |
104 | Lysosome_Homo sapiens_hsa04142 | 0.42814897 |
105 | Glioma_Homo sapiens_hsa05214 | 0.41800745 |
106 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.40018030 |
107 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.39263506 |
108 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.38949403 |
109 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.38786332 |
110 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.38756109 |
111 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.38619121 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.37021925 |
113 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.36755013 |
114 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.36432690 |
115 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.34337165 |
116 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.34311182 |
117 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.33112251 |
118 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.29055748 |
119 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.28712833 |
120 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.28126273 |
121 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.27925809 |
122 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.27137267 |
123 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.23721148 |
124 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.22058213 |
125 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.22003789 |
126 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.21321067 |
127 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.20672103 |
128 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.20305378 |
129 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.20146023 |
130 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.18995313 |
131 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.18059390 |
132 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.18042904 |
133 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.17617049 |
134 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.17448237 |
135 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.14468966 |