SCML4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.76956557
2negative T cell selection (GO:0043383)6.27251768
3interferon-gamma production (GO:0032609)5.97778132
4negative thymic T cell selection (GO:0045060)5.91653119
5negative regulation of cell killing (GO:0031342)5.66834038
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.66834038
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.48689461
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.48689461
9positive T cell selection (GO:0043368)5.44098987
10regulation of gamma-delta T cell differentiation (GO:0045586)5.33337099
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.26987747
12positive thymic T cell selection (GO:0045059)5.17783234
13positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.16005816
14regulation of gamma-delta T cell activation (GO:0046643)5.11937586
15T cell selection (GO:0045058)5.11790423
16regulation of isotype switching to IgG isotypes (GO:0048302)5.08826587
17antigen processing and presentation of endogenous antigen (GO:0019883)5.07105968
18regulation of T cell tolerance induction (GO:0002664)5.03469075
19thymic T cell selection (GO:0045061)4.96976232
20cellular response to interleukin-15 (GO:0071350)4.95545273
21tolerance induction (GO:0002507)4.89699919
22T cell migration (GO:0072678)4.88818928
23response to interleukin-15 (GO:0070672)4.84040696
24T cell receptor signaling pathway (GO:0050852)4.60332459
25regulation of regulatory T cell differentiation (GO:0045589)4.51162511
26regulation of T cell mediated cytotoxicity (GO:0001914)4.42903446
27positive regulation of interleukin-2 production (GO:0032743)4.24563345
28positive regulation of T cell mediated cytotoxicity (GO:0001916)4.23949004
29leukocyte aggregation (GO:0070486)4.19400550
30regulation of B cell receptor signaling pathway (GO:0050855)4.17812765
31regulation of T cell receptor signaling pathway (GO:0050856)4.10620616
32antigen receptor-mediated signaling pathway (GO:0050851)4.10507571
33antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.09215230
34positive regulation of tolerance induction (GO:0002645)4.03751188
35regulation of alpha-beta T cell proliferation (GO:0046640)3.96775524
36regulation of leukocyte mediated cytotoxicity (GO:0001910)3.95606715
37negative regulation of T cell mediated immunity (GO:0002710)3.94587375
38regulation of interleukin-2 biosynthetic process (GO:0045076)3.92682264
39regulation of tolerance induction (GO:0002643)3.88833064
40regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.87127640
41mast cell activation (GO:0045576)3.85734063
42alpha-beta T cell differentiation (GO:0046632)3.78171969
43alpha-beta T cell activation (GO:0046631)3.78131229
44negative regulation of leukocyte mediated immunity (GO:0002704)3.77559452
45T cell costimulation (GO:0031295)3.77110021
46lymphocyte costimulation (GO:0031294)3.74025146
47activated T cell proliferation (GO:0050798)3.72842927
48regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.72052572
49regulation of cell killing (GO:0031341)3.68316989
50positive regulation of T cell differentiation in thymus (GO:0033089)3.68068207
51positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.63912443
52positive regulation of alpha-beta T cell proliferation (GO:0046641)3.60696471
53positive regulation of isotype switching (GO:0045830)3.52593710
54positive regulation of DNA recombination (GO:0045911)3.52132150
55T cell differentiation (GO:0030217)3.51755454
56CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.48747093
57T-helper cell differentiation (GO:0042093)3.48747093
58mast cell degranulation (GO:0043303)3.48627593
59mast cell activation involved in immune response (GO:0002279)3.48627593
60positive regulation of defense response to virus by host (GO:0002230)3.44693473
61regulation of isotype switching (GO:0045191)3.38017074
62regulation of memory T cell differentiation (GO:0043380)3.32788422
63negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.32734045
64regulation of T cell mediated immunity (GO:0002709)3.32349952
65leukocyte degranulation (GO:0043299)3.31760008
66positive regulation of cell killing (GO:0031343)3.30783561
67regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.30476364
68positive regulation of T cell mediated immunity (GO:0002711)3.28019933
69regulation of interleukin-12 biosynthetic process (GO:0045075)3.27447479
70dendritic cell migration (GO:0036336)3.24048470
71myeloid dendritic cell activation (GO:0001773)3.22747225
72response to type I interferon (GO:0034340)3.21522208
73antigen processing and presentation via MHC class Ib (GO:0002475)3.21345584
74neutrophil activation (GO:0042119)3.20952545
75T cell homeostasis (GO:0043029)3.19073704
76regulation of germinal center formation (GO:0002634)3.18680214
77negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.17082280
78lymph node development (GO:0048535)3.16265075
79NIK/NF-kappaB signaling (GO:0038061)3.14555061
80CD4-positive, alpha-beta T cell differentiation (GO:0043367)3.14537557
81alpha-beta T cell differentiation involved in immune response (GO:0002293)3.14519467
82alpha-beta T cell activation involved in immune response (GO:0002287)3.14519467
83T cell differentiation involved in immune response (GO:0002292)3.14519467
84regulation of interleukin-2 production (GO:0032663)3.14426830
85type I interferon signaling pathway (GO:0060337)3.13967033
86cellular response to type I interferon (GO:0071357)3.13967033
87positive regulation of humoral immune response (GO:0002922)3.13406537
88regulation of B cell differentiation (GO:0045577)3.12286138
89negative regulation of innate immune response (GO:0045824)3.11688992
90T cell activation (GO:0042110)3.10993029
91positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.08885900
92natural killer cell activation (GO:0030101)3.08078415
93B cell receptor signaling pathway (GO:0050853)3.07685159
94negative regulation of adaptive immune response (GO:0002820)3.07027608
95mature B cell differentiation (GO:0002335)3.06402651
96cellular response to interferon-beta (GO:0035458)3.06341352
97V(D)J recombination (GO:0033151)3.03190222
98protein K11-linked deubiquitination (GO:0035871)3.02766962
99negative regulation of T cell receptor signaling pathway (GO:0050860)3.02471079
100CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.01455927
101T cell lineage commitment (GO:0002360)3.01107553
102negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.00497751
103negative regulation of lymphocyte mediated immunity (GO:0002707)2.97993567
104B cell proliferation (GO:0042100)2.94466717
105positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.94418416
106positive regulation of natural killer cell mediated immunity (GO:0002717)2.94418416
107DNA deamination (GO:0045006)2.93981245
108regulation of immunoglobulin production (GO:0002637)2.93866053
109leukocyte cell-cell adhesion (GO:0007159)2.93376425
110positive regulation of interferon-gamma production (GO:0032729)2.92979787
111positive regulation of immunoglobulin mediated immune response (GO:0002891)2.92631191
112positive regulation of B cell mediated immunity (GO:0002714)2.92631191
113neutrophil activation involved in immune response (GO:0002283)2.90740240
114positive regulation of granulocyte differentiation (GO:0030854)2.89567676
115regulation of defense response to virus by host (GO:0050691)2.88658978
116regulation of alpha-beta T cell activation (GO:0046634)2.88318061
117regulation of immunoglobulin mediated immune response (GO:0002889)2.88154310
118T cell activation involved in immune response (GO:0002286)2.87815988
119lymphocyte homeostasis (GO:0002260)2.87690405
120regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.86713272
121regulation of natural killer cell mediated immunity (GO:0002715)2.86713272
122cellular extravasation (GO:0045123)2.85664170
123positive regulation of immunoglobulin production (GO:0002639)2.84642862
124cellular defense response (GO:0006968)2.84173904
125interferon-gamma-mediated signaling pathway (GO:0060333)2.84020588
126CD4-positive, alpha-beta T cell activation (GO:0035710)2.83738465
127regulation of B cell mediated immunity (GO:0002712)2.83622764
128ribosomal small subunit assembly (GO:0000028)2.82979108
129dendritic cell chemotaxis (GO:0002407)2.82746571
130regulation of lymphocyte mediated immunity (GO:0002706)2.81978016
131T cell proliferation (GO:0042098)2.81786234
132positive regulation of alpha-beta T cell activation (GO:0046635)2.81348153
133positive regulation of B cell differentiation (GO:0045579)2.80805110
134natural killer cell differentiation (GO:0001779)2.76989803
135Peyers patch development (GO:0048541)2.76469325
136mucosal-associated lymphoid tissue development (GO:0048537)2.76469325
137granulocyte activation (GO:0036230)2.76442603
138positive regulation of adaptive immune response based on somatic recombination of immune receptors b2.74933084
139negative regulation of T-helper cell differentiation (GO:0045623)2.73646399
140negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.73646399
141myeloid cell activation involved in immune response (GO:0002275)2.73564184
142positive regulation of lymphocyte mediated immunity (GO:0002708)2.70925385

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.96056632
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.00221847
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.30609763
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.65153273
5RUNX_20019798_ChIP-Seq_JUKART_Human3.82173950
6* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.77904825
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.71469827
8* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.64975911
9STAT4_19710469_ChIP-ChIP_TH1__Mouse3.11127991
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.93710434
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.93532735
12NOTCH1_21737748_ChIP-Seq_TLL_Human2.85932472
13MYB_26560356_Chip-Seq_TH2_Human2.84443821
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.75045359
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.50046059
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.41133957
17SMAD_19615063_ChIP-ChIP_OVARY_Human2.40018175
18* MYB_26560356_Chip-Seq_TH1_Human2.32516811
19VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.09232227
20* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.05345684
21RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.01163859
22* IRF8_27001747_Chip-Seq_BMDM_Mouse1.97289725
23MAF_26560356_Chip-Seq_TH1_Human1.93886148
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.91621626
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89404688
26* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.85640169
27GATA3_27048872_Chip-Seq_THYMUS_Human1.85585086
28MYC_22102868_ChIP-Seq_BL_Human1.82232181
29UTX_26944678_Chip-Seq_JUKART_Human1.79257152
30SPI1_23547873_ChIP-Seq_NB4_Human1.77258085
31SCL_19346495_ChIP-Seq_HPC-7_Human1.76879794
32RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.75231448
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.63475855
34* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.58764593
35* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.52927948
36FLI1_27457419_Chip-Seq_LIVER_Mouse1.50681578
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49913386
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.45848299
39LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.37693487
40GATA3_26560356_Chip-Seq_TH2_Human1.36957343
41MAF_26560356_Chip-Seq_TH2_Human1.36217369
42E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.32472582
43ZNF274_21170338_ChIP-Seq_K562_Hela1.22921176
44PCGF2_27294783_Chip-Seq_NPCs_Mouse1.20696060
45ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18629430
46DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.17488796
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.14896980
48VDR_24763502_ChIP-Seq_THP-1_Human1.13444169
49ZFP57_27257070_Chip-Seq_ESCs_Mouse1.12621679
50PU_27001747_Chip-Seq_BMDM_Mouse1.12583274
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.12032183
52ELK1_19687146_ChIP-ChIP_HELA_Human1.11815110
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10570542
54VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.07821753
55CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07472964
56SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07129287
57* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.06742307
58CIITA_25753668_ChIP-Seq_RAJI_Human1.06488570
59MYB_21317192_ChIP-Seq_ERMYB_Mouse1.06452843
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05406871
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05310846
62IRF1_19129219_ChIP-ChIP_H3396_Human1.05246634
63* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.03913873
64* RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.03624923
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02838981
66SPI1_23127762_ChIP-Seq_K562_Human1.02619935
67POU3F2_20337985_ChIP-ChIP_501MEL_Human1.01999847
68* BCL6_27268052_Chip-Seq_Bcells_Human1.01826280
69* SMRT_27268052_Chip-Seq_Bcells_Human1.01487961
70EGR1_19374776_ChIP-ChIP_THP-1_Human0.99773118
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.98862053
72* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.98416149
73GATA3_26560356_Chip-Seq_TH1_Human0.98282470
74SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97873496
75GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97835318
76* EZH2_27294783_Chip-Seq_NPCs_Mouse0.97793110
77* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.97493994
78VDR_22108803_ChIP-Seq_LS180_Human0.95217914
79NMYC_18555785_Chip-Seq_ESCs_Mouse0.95179751
80GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94696476
81RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.94064800
82GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93056923
83FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89631112
84NANOG_20526341_ChIP-Seq_ESCs_Human0.88529014
85SUZ12_18555785_Chip-Seq_ESCs_Mouse0.87578645
86GATA1_19941827_ChIP-Seq_MEL_Mouse0.87366240
87GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87330991
88CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86925531
89RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86769107
90STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86763149
91RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.86396206
92* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.85289066
93VDR_24787735_ChIP-Seq_THP-1_Human0.84574857
94STAT3_18555785_Chip-Seq_ESCs_Mouse0.84168431
95P300_27268052_Chip-Seq_Bcells_Human0.84035378
96VDR_21846776_ChIP-Seq_THP-1_Human0.83818731
97EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.83631457
98KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.83153497
99TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.82845167
100* VDR_23849224_ChIP-Seq_CD4+_Human0.82756511
101* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.82680726
102TP63_19390658_ChIP-ChIP_HaCaT_Human0.81478953
103PU.1_20513432_ChIP-Seq_Bcells_Mouse0.81233152
104Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.81021496
105DROSHA_22980978_ChIP-Seq_HELA_Human0.80130690
106PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.79795334
107SPI1_20517297_ChIP-Seq_HL60_Human0.79740498
108FOXP3_21729870_ChIP-Seq_TREG_Human0.79699639
109FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.79280340
110GATA1_22025678_ChIP-Seq_K562_Human0.78924692
111NANOG_18555785_Chip-Seq_ESCs_Mouse0.78349783
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.78341817
113GATA3_21878914_ChIP-Seq_MCF-7_Human0.77551866
114GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.77417656
115P53_22387025_ChIP-Seq_ESCs_Mouse0.77178016
116TAF15_26573619_Chip-Seq_HEK293_Human0.77148841
117ER_23166858_ChIP-Seq_MCF-7_Human0.76939985
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.76587846
119STAT1_20625510_ChIP-Seq_HELA_Human0.76210146
120PRDM14_20953172_ChIP-Seq_ESCs_Human0.75664879
121EGR1_23403033_ChIP-Seq_LIVER_Mouse0.75621674
122CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75594777
123CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75385777
124GATA1_19941826_ChIP-Seq_K562_Human0.75355154
125TCF7_22412390_ChIP-Seq_EML_Mouse0.75342780
126PU1_27457419_Chip-Seq_LIVER_Mouse0.75260437
127CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75119750
128CMYC_18555785_Chip-Seq_ESCs_Mouse0.74466526
129ZFX_18555785_Chip-Seq_ESCs_Mouse0.74206781
130GABP_17652178_ChIP-ChIP_JURKAT_Human0.72864337
131OCT4_18555785_Chip-Seq_ESCs_Mouse0.72443450
132GATA2_21666600_ChIP-Seq_HMVEC_Human0.72395589
133EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.72046614
134FOXA1_27270436_Chip-Seq_PROSTATE_Human0.71473050
135FOXA1_25329375_ChIP-Seq_VCAP_Human0.71473050
136BCAT_22108803_ChIP-Seq_LS180_Human0.71411458
137GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.71384395
138RUNX1_27457419_Chip-Seq_LIVER_Mouse0.70941588
139FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.70764204
140P300_19829295_ChIP-Seq_ESCs_Human0.70209980

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology5.20357263
2MP0005671_abnormal_response_to4.09482318
3MP0001835_abnormal_antigen_presentation3.80492434
4MP0000685_abnormal_immune_system3.24136880
5MP0005387_immune_system_phenotype3.21936366
6MP0001790_abnormal_immune_system3.21936366
7MP0001800_abnormal_humoral_immune3.18354826
8MP0005000_abnormal_immune_tolerance2.88050617
9MP0002420_abnormal_adaptive_immunity2.74812635
10MP0002723_abnormal_immune_serum2.74312089
11MP0001819_abnormal_immune_cell2.70932781
12MP0001873_stomach_inflammation2.64352322
13MP0009785_altered_susceptibility_to2.61977833
14MP0002452_abnormal_antigen_presenting2.60341837
15MP0002148_abnormal_hypersensitivity_rea2.57137567
16MP0003866_abnormal_defecation2.47691082
17MP0002398_abnormal_bone_marrow2.47683519
18MP0005025_abnormal_response_to2.30446328
19MP0010155_abnormal_intestine_physiology2.29601979
20MP0000716_abnormal_immune_system2.24527300
21MP0002166_altered_tumor_susceptibility2.22329641
22MP0000703_abnormal_thymus_morphology2.18379424
23MP0002163_abnormal_gland_morphology2.15057533
24MP0003724_increased_susceptibility_to2.11813809
25MP0002405_respiratory_system_inflammati2.05743869
26MP0002006_tumorigenesis2.05605427
27MP0009333_abnormal_splenocyte_physiolog2.05210562
28MP0004381_abnormal_hair_follicle1.94958663
29MP0005174_abnormal_tail_pigmentation1.92202974
30MP0002722_abnormal_immune_system1.90953706
31MP0002009_preneoplasia1.89385055
32MP0000689_abnormal_spleen_morphology1.87085382
33MP0002396_abnormal_hematopoietic_system1.86476504
34MP0003787_abnormal_imprinting1.81281837
35MP0005075_abnormal_melanosome_morpholog1.80091431
36MP0002419_abnormal_innate_immunity1.79802807
37MP0003436_decreased_susceptibility_to1.77147151
38MP0001986_abnormal_taste_sensitivity1.76957175
39MP0002429_abnormal_blood_cell1.71636121
40MP0005310_abnormal_salivary_gland1.70399636
41MP0002822_catalepsy1.66561691
42MP0001845_abnormal_inflammatory_respons1.64497438
43MP0000015_abnormal_ear_pigmentation1.61798998
44MP0002277_abnormal_respiratory_mucosa1.61472298
45MP0006082_CNS_inflammation1.58405314
46MP0003300_gastrointestinal_ulcer1.54488036
47MP0003878_abnormal_ear_physiology1.54187199
48MP0005377_hearing/vestibular/ear_phenot1.54187199
49MP0004947_skin_inflammation1.52534713
50MP0000490_abnormal_crypts_of1.49695870
51MP0005464_abnormal_platelet_physiology1.44285086
52MP0002132_abnormal_respiratory_system1.40886899
53MP0005379_endocrine/exocrine_gland_phen1.39709403
54MP0008877_abnormal_DNA_methylation1.30577665
55MP0004808_abnormal_hematopoietic_stem1.29301595
56MP0004130_abnormal_muscle_cell1.25023591
57MP0009379_abnormal_foot_pigmentation1.23906263
58MP0002933_joint_inflammation1.22353344
59MP0000372_irregular_coat_pigmentation1.20944506
60MP0006292_abnormal_olfactory_placode1.19500561
61MP0004510_myositis1.19201638
62MP0002638_abnormal_pupillary_reflex1.17598960
63MP0001853_heart_inflammation1.16819912
64MP0002693_abnormal_pancreas_physiology1.14055041
65MP0001188_hyperpigmentation1.11971468
66MP0000858_altered_metastatic_potential1.10066964
67MP0000465_gastrointestinal_hemorrhage1.08324023
68MP0001501_abnormal_sleep_pattern1.07007164
69MP0002095_abnormal_skin_pigmentation1.05079928
70MP0005645_abnormal_hypothalamus_physiol1.02247418
71MP0010386_abnormal_urinary_bladder1.01400143
72MP0001919_abnormal_reproductive_system0.98516810
73MP0001663_abnormal_digestive_system0.97742868
74MP0003252_abnormal_bile_duct0.97206997
75MP0003183_abnormal_peptide_metabolism0.94364076
76MP0008057_abnormal_DNA_replication0.92763891
77MP0002102_abnormal_ear_morphology0.92100041
78MP0004142_abnormal_muscle_tone0.85054920
79MP0003646_muscle_fatigue0.83087615
80MP0001765_abnormal_ion_homeostasis0.82876263
81MP0001968_abnormal_touch/_nociception0.82401897
82MP0008469_abnormal_protein_level0.81807665
83MP0003195_calcinosis0.77838639
84MP0002735_abnormal_chemical_nociception0.75079516
85MP0004043_abnormal_pH_regulation0.74862375
86MP0003828_pulmonary_edema0.74377740
87MP0002998_abnormal_bone_remodeling0.73148568
88MP0003045_fibrosis0.71320937
89MP0003638_abnormal_response/metabolism_0.70380772
90MP0008872_abnormal_physiological_respon0.70373131
91MP0003448_altered_tumor_morphology0.69921403
92MP0009278_abnormal_bone_marrow0.69536467
93MP0008875_abnormal_xenobiotic_pharmacok0.68312309
94MP0005409_darkened_coat_color0.67966892
95MP0003011_delayed_dark_adaptation0.67630356
96MP0001533_abnormal_skeleton_physiology0.67556245
97MP0003172_abnormal_lysosome_physiology0.66587484
98MP0004883_abnormal_blood_vessel0.66315343
99MP0009764_decreased_sensitivity_to0.65668718
100MP0000613_abnormal_salivary_gland0.65545542
101MP0008995_early_reproductive_senescence0.63989128
102MP0009763_increased_sensitivity_to0.63479953
103MP0002138_abnormal_hepatobiliary_system0.61548992
104MP0002876_abnormal_thyroid_physiology0.59797093
105MP0008961_abnormal_basal_metabolism0.57687008
106MP0001905_abnormal_dopamine_level0.57621913
107MP0005390_skeleton_phenotype0.56961465
108MP0001664_abnormal_digestion0.56850005
109MP0008058_abnormal_DNA_repair0.56780715
110MP0000569_abnormal_digit_pigmentation0.56422921
111MP0005389_reproductive_system_phenotype0.53214858
112MP0000604_amyloidosis0.53008176
113MP0005167_abnormal_blood-brain_barrier0.52253911
114MP0009765_abnormal_xenobiotic_induced0.52226101
115MP0003786_premature_aging0.51206305
116MP0005381_digestive/alimentary_phenotyp0.51070520
117MP0004742_abnormal_vestibular_system0.50129197
118MP0001348_abnormal_lacrimal_gland0.48461679
119MP0002019_abnormal_tumor_incidence0.48003424
120MP0002928_abnormal_bile_duct0.47733416
121MP0003303_peritoneal_inflammation0.47494965
122MP0000477_abnormal_intestine_morphology0.47214603
123MP0005397_hematopoietic_system_phenotyp0.46856170
124MP0001545_abnormal_hematopoietic_system0.46856170
125MP0003943_abnormal_hepatobiliary_system0.45882760
126MP0001851_eye_inflammation0.44873571
127MP0000678_abnormal_parathyroid_gland0.44453480
128MP0000470_abnormal_stomach_morphology0.44390576
129MP0002136_abnormal_kidney_physiology0.42223777
130MP0006054_spinal_hemorrhage0.41849303
131MP0008569_lethality_at_weaning0.40677780

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.91800818
2Abnormality of T cell number (HP:0011839)5.74250179
3Elevated erythrocyte sedimentation rate (HP:0003565)4.70142940
4Panhypogammaglobulinemia (HP:0003139)4.34258828
5Severe combined immunodeficiency (HP:0004430)4.31400230
6Abnormal delayed hypersensitivity skin test (HP:0002963)4.29254425
7Abnormality of T cells (HP:0002843)4.29066493
8IgM deficiency (HP:0002850)4.24252236
9Recurrent bronchitis (HP:0002837)4.07620452
10Agammaglobulinemia (HP:0004432)3.97548266
11Recurrent viral infections (HP:0004429)3.93106478
12Combined immunodeficiency (HP:0005387)3.92702631
13Recurrent fungal infections (HP:0002841)3.92578611
14Stomatitis (HP:0010280)3.91931456
15Thyroiditis (HP:0100646)3.86701717
16Increased IgM level (HP:0003496)3.77971753
17Chronic mucocutaneous candidiasis (HP:0002728)3.77781798
18Recurrent cutaneous fungal infections (HP:0011370)3.77781798
19IgG deficiency (HP:0004315)3.73777998
20Chronic otitis media (HP:0000389)3.66517957
21Abnormality of the fingertips (HP:0001211)3.58781112
22Abnormality of eosinophils (HP:0001879)3.48287413
23Keratoconjunctivitis (HP:0001096)3.41802096
24Pustule (HP:0200039)3.38963423
25Autoimmune hemolytic anemia (HP:0001890)3.35729718
26Autoimmune thrombocytopenia (HP:0001973)3.34772934
27Eosinophilia (HP:0001880)3.33399135
28Cheilitis (HP:0100825)3.33020449
29Chronic diarrhea (HP:0002028)3.29721029
30Meningitis (HP:0001287)3.29655535
31Abnormality of B cell number (HP:0010975)3.21709735
32B lymphocytopenia (HP:0010976)3.21709735
33Myositis (HP:0100614)3.20301993
34Lymphopenia (HP:0001888)3.16874505
35Chronic sinusitis (HP:0011109)3.08898380
36Mediastinal lymphadenopathy (HP:0100721)3.06208443
37Hypothermia (HP:0002045)3.04840701
38Vasculitis (HP:0002633)3.02833319
39Abnormality of cells of the lymphoid lineage (HP:0012140)2.99456447
40Granulocytopenia (HP:0001913)2.97251206
41Recurrent abscess formation (HP:0002722)2.96925045
42Eczematoid dermatitis (HP:0000976)2.92983110
43Optic neuritis (HP:0100653)2.90004120
44Retrobulbar optic neuritis (HP:0100654)2.90004120
45Recurrent sinusitis (HP:0011108)2.87480498
46Abnormal hair whorl (HP:0010721)2.87235397
47Nasal polyposis (HP:0100582)2.86992861
48Inflammation of the large intestine (HP:0002037)2.85756151
49Abnormality of T cell physiology (HP:0011840)2.85686524
50Encephalitis (HP:0002383)2.69027393
51Obstructive lung disease (HP:0006536)2.67265323
52Chronic obstructive pulmonary disease (HP:0006510)2.67265323
53Leukocytosis (HP:0001974)2.66529050
54Congenital stationary night blindness (HP:0007642)2.65999773
55Joint swelling (HP:0001386)2.62688895
56Gastrointestinal inflammation (HP:0004386)2.62302186
57Anorexia (HP:0002039)2.59886882
58Hemoptysis (HP:0002105)2.52864854
59Lymphoma (HP:0002665)2.47653586
60Pulmonary infiltrates (HP:0002113)2.46588777
61Pulmonary embolism (HP:0002204)2.45854345
62Abnormality of macrophages (HP:0004311)2.45370681
63Prolonged bleeding time (HP:0003010)2.44003396
64Abnormality of the prostate (HP:0008775)2.38430630
65Recurrent skin infections (HP:0001581)2.33008424
66Bronchiectasis (HP:0002110)2.32736333
67Hypoplasia of the thymus (HP:0000778)2.32279690
68Gastrointestinal infarctions (HP:0005244)2.31909418
69Abnormality of the nasal mucosa (HP:0000433)2.29006099
70Orchitis (HP:0100796)2.28630417
71Bronchitis (HP:0012387)2.27846429
72Recurrent gram-negative bacterial infections (HP:0005420)2.27185010
73Recurrent bacterial skin infections (HP:0005406)2.25678594
74IgA deficiency (HP:0002720)2.25109993
75Chest pain (HP:0100749)2.23248353
76Gangrene (HP:0100758)2.23133093
77Verrucae (HP:0200043)2.20590022
78Papilloma (HP:0012740)2.20590022
79Hypochromic anemia (HP:0001931)2.16563940
80Abnormality of the pleura (HP:0002103)2.16480060
81Hypergammaglobulinemia (HP:0010702)2.14341048
82Colitis (HP:0002583)2.12893647
83Spontaneous hematomas (HP:0007420)2.12577249
84Attenuation of retinal blood vessels (HP:0007843)2.12448507
85Renal cortical cysts (HP:0000803)2.09156307
86Alveolar cell carcinoma (HP:0006519)2.08712286
87Gastrointestinal stroma tumor (HP:0100723)2.05441389
88Absent rod-and cone-mediated responses on ERG (HP:0007688)2.04754492
89Periodontitis (HP:0000704)2.04307295
90Gingivitis (HP:0000230)2.00915986
91Episodic fever (HP:0001954)1.98794839
92Ureteral stenosis (HP:0000071)1.97922989
93Abnormal rod and cone electroretinograms (HP:0008323)1.97901282
94Neoplasm of the tracheobronchial system (HP:0100552)1.97276218
95Abolished electroretinogram (ERG) (HP:0000550)1.97014598
96Petechiae (HP:0000967)1.95545974
97Pulmonary fibrosis (HP:0002206)1.95517924
98Prostate neoplasm (HP:0100787)1.94421645
99Hypochromic microcytic anemia (HP:0004840)1.94177539
100Vertigo (HP:0002321)1.92445419
101Hypoproteinemia (HP:0003075)1.91538143
102Ureteral obstruction (HP:0006000)1.91350153
103Increased IgE level (HP:0003212)1.90646209
104Hematochezia (HP:0002573)1.90416837
105Stomach cancer (HP:0012126)1.89975180
106Abnormality of the renal cortex (HP:0011035)1.89554641
107Thrombocytosis (HP:0001894)1.88528166
108Recurrent otitis media (HP:0000403)1.88244216
109Lip pit (HP:0100267)1.87949775
110Urticaria (HP:0001025)1.87333323
111Optic nerve coloboma (HP:0000588)1.85334437
112Dry hair (HP:0011359)1.84342622
113Sepsis (HP:0100806)1.83395440
114Glomerulopathy (HP:0100820)1.82305255
115Neutropenia (HP:0001875)1.80689156
116Clumsiness (HP:0002312)1.80019838
117Hemiplegia (HP:0002301)1.78490457
118Gingival bleeding (HP:0000225)1.76284595
119Epistaxis (HP:0000421)1.75353842
120Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.74202809
121Microcytic anemia (HP:0001935)1.71694447
122Abnormality of DNA repair (HP:0003254)1.71692443
123Keratitis (HP:0000491)1.70371313
124Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.69804463
125Keratoconjunctivitis sicca (HP:0001097)1.69463852
126Congenital sensorineural hearing impairment (HP:0008527)1.69070502
127Arterial thrombosis (HP:0004420)1.68059936
128Cellulitis (HP:0100658)1.65850984
129Type I transferrin isoform profile (HP:0003642)1.65698626
130Recurrent pneumonia (HP:0006532)1.63853201

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.72306785
2MAP4K15.32711284
3JAK32.96172687
4NLK2.91282072
5MAP3K142.80035508
6ITK2.66596429
7IKBKE2.49682839
8ZAP702.43974446
9MST42.41294689
10GRK62.34661642
11TEC2.28217919
12IRAK42.03540253
13TYK21.88648779
14IRAK31.86376380
15STK101.83655198
16FGFR41.81834564
17TESK21.77478031
18BTK1.61472375
19JAK11.60765518
20LCK1.60174807
21MAP3K131.59247403
22SYK1.59049336
23FGFR31.52822936
24MAP2K21.48453214
25IKBKB1.44649799
26SIK31.41700930
27MAP3K121.39118051
28TLK11.36459015
29TNIK1.24275622
30CAMKK21.22814063
31KDR1.19288543
32PRKCQ1.19248189
33TBK11.16292221
34MARK31.16056771
35BLK1.14844744
36TGFBR21.09102767
37HCK1.08333914
38YES11.07376923
39FRK1.07051104
40ADRBK21.06925690
41TNK21.05020309
42CHUK1.04098951
43MAP3K101.01972726
44CSK1.01038293
45NUAK11.00482179
46BCKDK0.99304397
47IRAK10.96723015
48STK240.95413991
49PRKCH0.89134588
50PRKD20.88635165
51FLT30.88348019
52KIT0.87716538
53HIPK20.85696290
54NME20.85488336
55SIK20.85313358
56PIM10.84709544
57LYN0.84676672
58PINK10.84559165
59BMPR20.83022028
60EPHA30.82055897
61CLK10.79883895
62GRK70.79683477
63CASK0.79403394
64MAP4K20.75992367
65CAMKK10.70767127
66EIF2AK20.67056622
67FYN0.65177164
68MAPK70.64675422
69MAPK110.64486601
70ERN10.64116627
71MAP3K110.63504053
72EIF2AK30.63031703
73PDK10.62696224
74MAPK130.62616783
75INSRR0.62517226
76MAP3K70.62254153
77MAP2K70.61598873
78LMTK20.61058428
79MAP2K60.60956995
80RIPK40.60834125
81FGR0.60271637
82TRPM70.60112865
83TAOK30.59815237
84BMPR1B0.56980614
85EPHB10.55755609
86BRD40.55450166
87PASK0.54875924
88IRAK20.53550533
89PIK3CA0.53547510
90PRKG20.53477086
91JAK20.51832071
92ADRBK10.51751532
93MATK0.51392317
94SGK20.51064678
95GRK10.46990431
96FES0.45495953
97STK40.45474488
98MUSK0.44974570
99ACVR1B0.44557852
100TAOK10.43863193
101ZAK0.43281541
102MARK20.39839675
103ERBB30.39775068
104CSF1R0.39574499
105NTRK20.39123693
106PTK2B0.39066126
107NEK60.37985942
108PIK3CG0.35788098
109MAP3K30.35091892
110MAPK30.34602942
111STK380.34376265
112RPS6KA50.33664603
113CDK40.33344357
114IGF1R0.32326121
115RPS6KA60.31865999
116ABL10.31315850
117CAMK10.31014677
118STK110.30745527
119LRRK20.30609543
120EEF2K0.30112707
121MAPK120.29999859
122MAP2K30.29226210
123CAMK40.28600702
124MAPKAPK20.28399232
125MAP3K10.28277655
126INSR0.27826408
127TGFBR10.27634318
128MAPK40.27101091
129PKN10.26543253
130SRPK10.26142136
131PRKCD0.25953785
132DYRK1A0.25330765
133VRK10.24861932
134PDGFRB0.23834417

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.72536250
2T cell receptor signaling pathway_Homo sapiens_hsa046602.86409794
3Intestinal immune network for IgA production_Homo sapiens_hsa046722.86036816
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.46905304
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.42486169
6Graft-versus-host disease_Homo sapiens_hsa053322.37330483
7Measles_Homo sapiens_hsa051622.35659376
8Allograft rejection_Homo sapiens_hsa053302.24930094
9Hematopoietic cell lineage_Homo sapiens_hsa046402.22630588
10Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.20403640
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.09461757
12Autoimmune thyroid disease_Homo sapiens_hsa053201.88271043
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.85281495
14NOD-like receptor signaling pathway_Homo sapiens_hsa046211.68143382
15Leishmaniasis_Homo sapiens_hsa051401.66557013
16Osteoclast differentiation_Homo sapiens_hsa043801.62704267
17B cell receptor signaling pathway_Homo sapiens_hsa046621.61209949
18Staphylococcus aureus infection_Homo sapiens_hsa051501.56699325
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.55937845
20Herpes simplex infection_Homo sapiens_hsa051681.47981623
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.46326868
22Antigen processing and presentation_Homo sapiens_hsa046121.45794185
23Ribosome_Homo sapiens_hsa030101.45372497
24Type I diabetes mellitus_Homo sapiens_hsa049401.42204049
25Influenza A_Homo sapiens_hsa051641.36831187
26Non-homologous end-joining_Homo sapiens_hsa034501.33055303
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.28249924
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27417236
29Chemokine signaling pathway_Homo sapiens_hsa040621.26433966
30Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.25379135
31Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.20699451
32Toxoplasmosis_Homo sapiens_hsa051451.14158746
33Linoleic acid metabolism_Homo sapiens_hsa005911.13706683
34Viral myocarditis_Homo sapiens_hsa054161.11729161
35TNF signaling pathway_Homo sapiens_hsa046681.11315016
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.09656713
37Acute myeloid leukemia_Homo sapiens_hsa052211.09421676
38Hepatitis B_Homo sapiens_hsa051611.07173690
39Protein export_Homo sapiens_hsa030601.02864084
40Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99714321
41Hepatitis C_Homo sapiens_hsa051600.96420504
42Leukocyte transendothelial migration_Homo sapiens_hsa046700.95858025
43Rheumatoid arthritis_Homo sapiens_hsa053230.93805151
44Nitrogen metabolism_Homo sapiens_hsa009100.93665335
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.93477586
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.90965284
47Arachidonic acid metabolism_Homo sapiens_hsa005900.90145141
48Prolactin signaling pathway_Homo sapiens_hsa049170.89625215
49Asthma_Homo sapiens_hsa053100.87459020
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85458912
51Apoptosis_Homo sapiens_hsa042100.84337607
52Phototransduction_Homo sapiens_hsa047440.84151907
53Legionellosis_Homo sapiens_hsa051340.81619137
54Colorectal cancer_Homo sapiens_hsa052100.77272361
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76590387
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.75495937
57Tuberculosis_Homo sapiens_hsa051520.75434313
58Pancreatic secretion_Homo sapiens_hsa049720.74265466
59Epstein-Barr virus infection_Homo sapiens_hsa051690.73493219
60Platelet activation_Homo sapiens_hsa046110.73162467
61Ether lipid metabolism_Homo sapiens_hsa005650.70490424
62Pancreatic cancer_Homo sapiens_hsa052120.70132836
63Inositol phosphate metabolism_Homo sapiens_hsa005620.69009475
64Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.68666215
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68338706
66Shigellosis_Homo sapiens_hsa051310.67543244
67African trypanosomiasis_Homo sapiens_hsa051430.65514620
68Pertussis_Homo sapiens_hsa051330.64497646
69Malaria_Homo sapiens_hsa051440.63938810
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63270940
71Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63158818
72HTLV-I infection_Homo sapiens_hsa051660.61364754
73Salmonella infection_Homo sapiens_hsa051320.61015606
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60382130
75Endometrial cancer_Homo sapiens_hsa052130.58083037
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.57608576
77Regulation of autophagy_Homo sapiens_hsa041400.57562436
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54223656
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52185153
80Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.52063096
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51612414
82FoxO signaling pathway_Homo sapiens_hsa040680.50201917
83Notch signaling pathway_Homo sapiens_hsa043300.49935868
84Olfactory transduction_Homo sapiens_hsa047400.49881719
85Dorso-ventral axis formation_Homo sapiens_hsa043200.49469415
86Prostate cancer_Homo sapiens_hsa052150.48752255
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.48346537
88RNA degradation_Homo sapiens_hsa030180.47819313
89Sphingolipid metabolism_Homo sapiens_hsa006000.47647339
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46144943
91Other glycan degradation_Homo sapiens_hsa005110.45634336
92Chronic myeloid leukemia_Homo sapiens_hsa052200.44720209
93ABC transporters_Homo sapiens_hsa020100.44408284
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42816236
95MAPK signaling pathway_Homo sapiens_hsa040100.42665240
96Endocytosis_Homo sapiens_hsa041440.41611887
97Viral carcinogenesis_Homo sapiens_hsa052030.40636162
98Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40232095
99Fanconi anemia pathway_Homo sapiens_hsa034600.38534711
100Serotonergic synapse_Homo sapiens_hsa047260.38212542
101Sphingolipid signaling pathway_Homo sapiens_hsa040710.37746664
102Thyroid cancer_Homo sapiens_hsa052160.37277129
103VEGF signaling pathway_Homo sapiens_hsa043700.37095658
104Taste transduction_Homo sapiens_hsa047420.35851139
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.35538730
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33875108
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32787562
108Glycerolipid metabolism_Homo sapiens_hsa005610.31427713
109Homologous recombination_Homo sapiens_hsa034400.30681832
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30282435
111Non-small cell lung cancer_Homo sapiens_hsa052230.30125357
112Base excision repair_Homo sapiens_hsa034100.29880883
113Ras signaling pathway_Homo sapiens_hsa040140.27613961
114Nicotine addiction_Homo sapiens_hsa050330.27353840
115RNA polymerase_Homo sapiens_hsa030200.26264648
116Phagosome_Homo sapiens_hsa041450.26074515
117Renin secretion_Homo sapiens_hsa049240.25846552
118Spliceosome_Homo sapiens_hsa030400.25620728
119Morphine addiction_Homo sapiens_hsa050320.25588354
120Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.24961288
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24835158
122Cholinergic synapse_Homo sapiens_hsa047250.24790361
123Ovarian steroidogenesis_Homo sapiens_hsa049130.23566349
124Insulin secretion_Homo sapiens_hsa049110.23215751
125Calcium signaling pathway_Homo sapiens_hsa040200.23156934
126Choline metabolism in cancer_Homo sapiens_hsa052310.22984613
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.22777249
128Peroxisome_Homo sapiens_hsa041460.22601847
129Vascular smooth muscle contraction_Homo sapiens_hsa042700.22212137
130Insulin resistance_Homo sapiens_hsa049310.21896219

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