SCOC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.43296058
2neuron cell-cell adhesion (GO:0007158)5.10305428
3vocalization behavior (GO:0071625)4.96208100
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.78769370
5neuronal action potential propagation (GO:0019227)4.59587121
6glutamate secretion (GO:0014047)4.50267858
7regulation of synaptic vesicle exocytosis (GO:2000300)4.49320517
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.37412008
9protein localization to synapse (GO:0035418)4.35029398
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.28388336
11synaptic vesicle maturation (GO:0016188)4.20907657
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.13819346
13neurotransmitter secretion (GO:0007269)4.03901820
14regulation of glutamate receptor signaling pathway (GO:1900449)4.03180521
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.99946721
16regulation of synaptic vesicle transport (GO:1902803)3.92466213
17gamma-aminobutyric acid signaling pathway (GO:0007214)3.92120833
18negative regulation of synaptic transmission, GABAergic (GO:0032229)3.90236682
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.89982802
20neuron-neuron synaptic transmission (GO:0007270)3.87779995
21presynaptic membrane assembly (GO:0097105)3.86142797
22glutamate receptor signaling pathway (GO:0007215)3.70159930
23presynaptic membrane organization (GO:0097090)3.69995913
24synaptic transmission, glutamatergic (GO:0035249)3.65015197
25ATP hydrolysis coupled proton transport (GO:0015991)3.64288656
26energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.64288656
27locomotory exploration behavior (GO:0035641)3.60122161
28neuron recognition (GO:0008038)3.57348448
29negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.50630365
30synaptic vesicle docking involved in exocytosis (GO:0016081)3.50421657
31neurotransmitter transport (GO:0006836)3.49063511
32pyrimidine nucleobase catabolic process (GO:0006208)3.47932970
33exploration behavior (GO:0035640)3.44635142
34regulation of long-term neuronal synaptic plasticity (GO:0048169)3.43675847
35transferrin transport (GO:0033572)3.42062009
36postsynaptic membrane organization (GO:0001941)3.40296459
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.38750176
38positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.32709583
39chaperone-mediated protein transport (GO:0072321)3.31925520
40transmission of nerve impulse (GO:0019226)3.31840632
41regulation of neuronal synaptic plasticity (GO:0048168)3.30459006
42neurotransmitter-gated ion channel clustering (GO:0072578)3.29620166
43nucleobase catabolic process (GO:0046113)3.28725217
44proline transport (GO:0015824)3.28200747
45membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.27714182
46gamma-aminobutyric acid transport (GO:0015812)3.27228216
47synaptic vesicle endocytosis (GO:0048488)3.25227645
48positive regulation of synapse assembly (GO:0051965)3.21396128
49regulation of neurotransmitter levels (GO:0001505)3.21225782
50mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.20729659
51trivalent inorganic cation transport (GO:0072512)3.19628233
52ferric iron transport (GO:0015682)3.19628233
53regulation of excitatory postsynaptic membrane potential (GO:0060079)3.19390443
54negative regulation of dendrite morphogenesis (GO:0050774)3.19310170
55regulation of synaptic transmission, glutamatergic (GO:0051966)3.18670446
56regulation of synapse structural plasticity (GO:0051823)3.18534751
57regulation of vesicle fusion (GO:0031338)3.17589959
58negative regulation of neurotransmitter transport (GO:0051589)3.12244530
59long-term synaptic potentiation (GO:0060291)3.11588998
60positive regulation of synaptic transmission, GABAergic (GO:0032230)3.10161294
61regulation of neurotransmitter secretion (GO:0046928)3.09957803
62regulation of postsynaptic membrane potential (GO:0060078)3.08895666
63startle response (GO:0001964)3.07527687
64mitochondrial fragmentation involved in apoptotic process (GO:0043653)3.06605541
65positive regulation of membrane potential (GO:0045838)3.05748662
66synaptic vesicle transport (GO:0048489)3.04968030
67establishment of synaptic vesicle localization (GO:0097480)3.04968030
68layer formation in cerebral cortex (GO:0021819)3.04305251
69dendritic spine morphogenesis (GO:0060997)3.04036615
70regulation of neurotransmitter transport (GO:0051588)3.01988058
71long-term memory (GO:0007616)2.99326164
72regulation of synaptic transmission, GABAergic (GO:0032228)2.98140860
73mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.97480547
74regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.96317928
75synapse assembly (GO:0007416)2.96027016
76cullin deneddylation (GO:0010388)2.94879187
77neuromuscular process controlling posture (GO:0050884)2.94601349
78axonal fasciculation (GO:0007413)2.94227062
79G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.93503435
80response to histamine (GO:0034776)2.92426524
81synaptic transmission (GO:0007268)2.91366169
82regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.91249503
83regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.91249503
84positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.90667801
85protein localization to cilium (GO:0061512)2.89537543
86auditory behavior (GO:0031223)2.86540331
87striatum development (GO:0021756)2.85747791
88establishment of vesicle localization (GO:0051650)2.83997746
89adult walking behavior (GO:0007628)2.83728309
90membrane hyperpolarization (GO:0060081)2.83480331
91detection of calcium ion (GO:0005513)2.83285049
92positive regulation of neurotransmitter transport (GO:0051590)2.82762763
93nonmotile primary cilium assembly (GO:0035058)2.82512425
94membrane depolarization (GO:0051899)2.82414366
95cerebellar Purkinje cell differentiation (GO:0021702)2.82404680
96positive regulation of synapse maturation (GO:0090129)2.82240336
97neurotransmitter uptake (GO:0001504)2.82186617
98regulation of synaptic plasticity (GO:0048167)2.82106689
99behavioral fear response (GO:0001662)2.81389076
100behavioral defense response (GO:0002209)2.81389076
101regulation of glutamate secretion (GO:0014048)2.81269780
102ATP synthesis coupled proton transport (GO:0015986)2.80698739
103energy coupled proton transport, down electrochemical gradient (GO:0015985)2.80698739
104learning (GO:0007612)2.80148288
105regulation of protein kinase A signaling (GO:0010738)2.79749685
106positive regulation of mitochondrial fission (GO:0090141)2.79724810
107dendrite development (GO:0016358)2.79243896
108synaptic transmission, dopaminergic (GO:0001963)2.77486621
109water-soluble vitamin biosynthetic process (GO:0042364)2.65437905
110peptidyl-cysteine modification (GO:0018198)2.60744821
111mechanosensory behavior (GO:0007638)2.55885631
112retinal ganglion cell axon guidance (GO:0031290)2.55737425
113protein deneddylation (GO:0000338)2.55456086
114neurofilament cytoskeleton organization (GO:0060052)2.54222281
115short-term memory (GO:0007614)2.50795472
116protein neddylation (GO:0045116)2.48653262
117ribonucleoprotein complex disassembly (GO:0032988)2.48230917
118intraciliary transport (GO:0042073)2.46397140
119negative regulation of membrane potential (GO:0045837)2.45645536
120establishment of mitochondrion localization (GO:0051654)2.44906105
121epithelial cilium movement (GO:0003351)2.44077429
122cellular potassium ion homeostasis (GO:0030007)2.43470955
123C4-dicarboxylate transport (GO:0015740)2.36968559
124glycosphingolipid biosynthetic process (GO:0006688)2.33728882
125respiratory electron transport chain (GO:0022904)2.33624903
126organelle disassembly (GO:1903008)2.32977208
127establishment of melanosome localization (GO:0032401)2.32828701
128anterograde axon cargo transport (GO:0008089)2.31515972
129dendritic spine organization (GO:0097061)2.31011496
130electron transport chain (GO:0022900)2.30952607
131regulation of feeding behavior (GO:0060259)2.30419143
132positive regulation of dendritic spine morphogenesis (GO:0061003)2.30065435
133glycerophospholipid catabolic process (GO:0046475)2.29997289
134sequestering of actin monomers (GO:0042989)2.29635353
135regulation of dendritic spine morphogenesis (GO:0061001)2.29173884
136respiratory chain complex IV assembly (GO:0008535)2.28758577
137neuronal ion channel clustering (GO:0045161)2.28212206
138response to auditory stimulus (GO:0010996)2.26285102
139melanosome transport (GO:0032402)2.26276603
140cellular ketone body metabolic process (GO:0046950)2.25747966
141calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.23678744
142vascular smooth muscle contraction (GO:0014829)2.21996511
143establishment of pigment granule localization (GO:0051905)2.18820112
144DNA double-strand break processing (GO:0000729)2.18348993
145dopamine biosynthetic process (GO:0042416)2.16803030
146righting reflex (GO:0060013)2.16693985
147negative regulation of cytosolic calcium ion concentration (GO:0051481)2.16396093

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.37805455
2GBX2_23144817_ChIP-Seq_PC3_Human4.37702445
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.09409215
4TAF15_26573619_Chip-Seq_HEK293_Human2.98432828
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.94723618
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91406926
7SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53212599
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.48379036
9REST_21632747_ChIP-Seq_MESCs_Mouse2.47247835
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.45129997
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.45129997
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.44117170
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42755527
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.39178977
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.27926559
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.25862560
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25733048
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25522429
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.24866543
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.22874473
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.21286300
22CTBP1_25329375_ChIP-Seq_LNCAP_Human2.15581202
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.07503404
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.05573348
25IGF1R_20145208_ChIP-Seq_DFB_Human1.98126768
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.95475518
27RBPJ_22232070_ChIP-Seq_NCS_Mouse1.94129956
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.92327885
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91448259
30EZH2_27294783_Chip-Seq_ESCs_Mouse1.91378027
31P300_19829295_ChIP-Seq_ESCs_Human1.89974491
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.86920567
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.86804268
34RARB_27405468_Chip-Seq_BRAIN_Mouse1.84881139
35* SMAD4_21799915_ChIP-Seq_A2780_Human1.84117420
36AR_21572438_ChIP-Seq_LNCaP_Human1.79368841
37FUS_26573619_Chip-Seq_HEK293_Human1.78236242
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71888753
39SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71807369
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68496271
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.66903443
42KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.65517151
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.64818813
44VDR_22108803_ChIP-Seq_LS180_Human1.63744524
45DROSHA_22980978_ChIP-Seq_HELA_Human1.62989825
46TOP2B_26459242_ChIP-Seq_MCF-7_Human1.61887205
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.61743141
48ZNF274_21170338_ChIP-Seq_K562_Hela1.59293390
49* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58618389
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56706685
51IKZF1_21737484_ChIP-ChIP_HCT116_Human1.56201651
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.54994069
53SALL1_21062744_ChIP-ChIP_HESCs_Human1.53140743
54RNF2_27304074_Chip-Seq_NSC_Mouse1.52246484
55GABP_17652178_ChIP-ChIP_JURKAT_Human1.48935101
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.47551270
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.46398774
58PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43763172
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.43662674
60ER_23166858_ChIP-Seq_MCF-7_Human1.41100675
61RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.40906241
62* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40012067
63AR_25329375_ChIP-Seq_VCAP_Human1.38312887
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34852390
65E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.34340190
66JUN_21703547_ChIP-Seq_K562_Human1.33999566
67* SOX2_21211035_ChIP-Seq_LN229_Gbm1.29885706
68* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28774791
69STAT3_23295773_ChIP-Seq_U87_Human1.27882477
70ELK1_19687146_ChIP-ChIP_HELA_Human1.26891626
71ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.26035089
72HTT_18923047_ChIP-ChIP_STHdh_Human1.20425900
73TAL1_26923725_Chip-Seq_HPCs_Mouse1.19217332
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18929498
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.18712528
76P53_22387025_ChIP-Seq_ESCs_Mouse1.17768338
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17295552
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16169184
79EWS_26573619_Chip-Seq_HEK293_Human1.14476489
80TCF4_23295773_ChIP-Seq_U87_Human1.14445974
81* RUNX2_22187159_ChIP-Seq_PCA_Human1.14009043
82EZH2_27294783_Chip-Seq_NPCs_Mouse1.13482897
83NANOG_18555785_Chip-Seq_ESCs_Mouse1.13116822
84FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12597484
85NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.10697051
86* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10267941
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.10163084
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09668110
89SMAD_19615063_ChIP-ChIP_OVARY_Human1.09048687
90HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.08625649
91KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08536360
92EST1_17652178_ChIP-ChIP_JURKAT_Human1.08524290
93CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07942056
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07500610
95FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.06310451
96* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05949447
97TP53_22573176_ChIP-Seq_HFKS_Human1.05770594
98CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05764098
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.05673612
100ERG_21242973_ChIP-ChIP_JURKAT_Human1.05221949
101P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04524510
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03663795
103SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01849064
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01725319
105NFE2_27457419_Chip-Seq_LIVER_Mouse1.01165105
106* TCF4_22108803_ChIP-Seq_LS180_Human0.99657968
107GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99527565
108MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99124037
109YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98572892
110RING1B_27294783_Chip-Seq_ESCs_Mouse0.97360042
111REST_19997604_ChIP-ChIP_NEURONS_Mouse0.96510702
112EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.96448931
113ARNT_22903824_ChIP-Seq_MCF-7_Human0.96005780
114WT1_19549856_ChIP-ChIP_CCG9911_Human0.95736161
115FLI1_27457419_Chip-Seq_LIVER_Mouse0.94854004
116EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94569285
117SOX9_26525672_Chip-Seq_HEART_Mouse0.93832696
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93325462
119CBP_20019798_ChIP-Seq_JUKART_Human0.93325462
120AR_19668381_ChIP-Seq_PC3_Human0.91975299
121KDM2B_26808549_Chip-Seq_REH_Human0.91623085
122BCAT_22108803_ChIP-Seq_LS180_Human0.91330838
123TP53_18474530_ChIP-ChIP_U2OS_Human0.90684613
124RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.90331965
125CMYC_18555785_Chip-Seq_ESCs_Mouse0.90246960
126CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.89969794
127E2F1_18555785_Chip-Seq_ESCs_Mouse0.89290549
128* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.88667677

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.90540739
2MP0004859_abnormal_synaptic_plasticity4.68492542
3MP0003635_abnormal_synaptic_transmissio3.63389082
4MP0004270_analgesia3.46689343
5MP0001968_abnormal_touch/_nociception3.25238415
6MP0009046_muscle_twitch3.22177244
7MP0009745_abnormal_behavioral_response3.21475779
8MP0002064_seizures3.13337917
9MP0002736_abnormal_nociception_after2.92045235
10MP0002063_abnormal_learning/memory/cond2.90663067
11MP0002734_abnormal_mechanical_nocicepti2.80546243
12MP0002735_abnormal_chemical_nociception2.75733273
13MP0002272_abnormal_nervous_system2.72229522
14MP0002572_abnormal_emotion/affect_behav2.67963766
15MP0001529_abnormal_vocalization2.62786540
16MP0006276_abnormal_autonomic_nervous2.62399536
17MP0001486_abnormal_startle_reflex2.35747616
18MP0001501_abnormal_sleep_pattern2.25014422
19MP0001440_abnormal_grooming_behavior2.24028696
20MP0002733_abnormal_thermal_nociception2.23574943
21MP0001970_abnormal_pain_threshold2.21318564
22MP0005423_abnormal_somatic_nervous2.20198870
23MP0002822_catalepsy2.13450738
24MP0002067_abnormal_sensory_capabilities2.13329365
25MP0001905_abnormal_dopamine_level2.12221312
26MP0003122_maternal_imprinting1.98243389
27MP0004142_abnormal_muscle_tone1.86243153
28MP0002184_abnormal_innervation1.83355877
29MP0000778_abnormal_nervous_system1.83236915
30MP0004924_abnormal_behavior1.82496309
31MP0005386_behavior/neurological_phenoty1.82496309
32MP0001188_hyperpigmentation1.80177854
33MP0005646_abnormal_pituitary_gland1.68153471
34MP0003787_abnormal_imprinting1.67872894
35MP0002557_abnormal_social/conspecific_i1.66767870
36MP0001984_abnormal_olfaction1.65337165
37MP0004811_abnormal_neuron_physiology1.53100265
38MP0008569_lethality_at_weaning1.50959043
39MP0000955_abnormal_spinal_cord1.49589612
40MP0002837_dystrophic_cardiac_calcinosis1.48222796
41MP0009780_abnormal_chondrocyte_physiolo1.47948906
42MP0002066_abnormal_motor_capabilities/c1.41184647
43MP0005187_abnormal_penis_morphology1.40350660
44MP0002882_abnormal_neuron_morphology1.39892239
45MP0001986_abnormal_taste_sensitivity1.35692569
46MP0005645_abnormal_hypothalamus_physiol1.35382056
47MP0003329_amyloid_beta_deposits1.34898595
48MP0005253_abnormal_eye_physiology1.28270949
49MP0004858_abnormal_nervous_system1.27853283
50MP0008789_abnormal_olfactory_epithelium1.27488762
51MP0002234_abnormal_pharynx_morphology1.25913493
52MP0003195_calcinosis1.24942761
53MP0003879_abnormal_hair_cell1.24093637
54MP0004133_heterotaxia1.20214016
55MP0010386_abnormal_urinary_bladder1.18864026
56MP0003011_delayed_dark_adaptation1.17563381
57MP0003123_paternal_imprinting1.15824930
58MP0000013_abnormal_adipose_tissue1.13179930
59MP0002909_abnormal_adrenal_gland1.11714172
60MP0002229_neurodegeneration1.08779495
61MP0001502_abnormal_circadian_rhythm1.08248595
62MP0002638_abnormal_pupillary_reflex1.05477158
63MP0000751_myopathy1.04187748
64MP0003633_abnormal_nervous_system1.03044170
65MP0004742_abnormal_vestibular_system1.02866349
66MP0005248_abnormal_Harderian_gland1.01248810
67MP0005551_abnormal_eye_electrophysiolog1.00795643
68MP0001963_abnormal_hearing_physiology1.00751296
69MP0002152_abnormal_brain_morphology1.00738980
70MP0000920_abnormal_myelination1.00677963
71MP0002876_abnormal_thyroid_physiology0.98646921
72MP0002938_white_spotting0.98157438
73MP0004885_abnormal_endolymph0.97540707
74MP0005171_absent_coat_pigmentation0.96980989
75MP0003631_nervous_system_phenotype0.96863464
76MP0003634_abnormal_glial_cell0.93587043
77MP0002653_abnormal_ependyma_morphology0.92978541
78MP0002752_abnormal_somatic_nervous0.91822314
79MP0004145_abnormal_muscle_electrophysio0.91323637
80MP0002160_abnormal_reproductive_system0.89704571
81MP0003890_abnormal_embryonic-extraembry0.88518380
82MP0000631_abnormal_neuroendocrine_gland0.88423732
83MP0008872_abnormal_physiological_respon0.87792651
84MP0004147_increased_porphyrin_level0.87481088
85MP0002069_abnormal_eating/drinking_beha0.85217605
86MP0001664_abnormal_digestion0.83678185
87MP0005394_taste/olfaction_phenotype0.83326211
88MP0005499_abnormal_olfactory_system0.83326211
89MP0000647_abnormal_sebaceous_gland0.82924503
90MP0004085_abnormal_heartbeat0.82402658
91MP0004215_abnormal_myocardial_fiber0.81990608
92MP0003283_abnormal_digestive_organ0.81480273
93MP0003121_genomic_imprinting0.81150287
94MP0002233_abnormal_nose_morphology0.79349308
95MP0004484_altered_response_of0.77844565
96MP0001177_atelectasis0.77436333
97MP0005084_abnormal_gallbladder_morpholo0.75453158
98MP0005535_abnormal_body_temperature0.75042599
99MP0003632_abnormal_nervous_system0.74803643
100MP0006292_abnormal_olfactory_placode0.74225617
101MP0000516_abnormal_urinary_system0.74107676
102MP0005367_renal/urinary_system_phenotyp0.74107676
103MP0006072_abnormal_retinal_apoptosis0.73077609
104MP0002090_abnormal_vision0.72968469
105MP0000639_abnormal_adrenal_gland0.72820830
106MP0001299_abnormal_eye_distance/0.72592578
107MP0005409_darkened_coat_color0.72300573
108MP0002751_abnormal_autonomic_nervous0.72029837
109MP0004043_abnormal_pH_regulation0.71552936
110MP0008874_decreased_physiological_sensi0.70403920
111MP0005195_abnormal_posterior_eye0.69244197
112MP0008877_abnormal_DNA_methylation0.69198853
113MP0001485_abnormal_pinna_reflex0.64187633
114MP0000026_abnormal_inner_ear0.62796879
115MP0006035_abnormal_mitochondrial_morpho0.62126800
116MP0004233_abnormal_muscle_weight0.62082329
117MP0001943_abnormal_respiration0.61351165
118MP0005379_endocrine/exocrine_gland_phen0.60549735
119MP0003690_abnormal_glial_cell0.58801057
120MP0002102_abnormal_ear_morphology0.58121728
121MP0003137_abnormal_impulse_conducting0.53147975
122MP0003183_abnormal_peptide_metabolism0.52660906

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.06642360
2Myokymia (HP:0002411)5.34587074
3Atonic seizures (HP:0010819)5.11299799
4Focal seizures (HP:0007359)4.75642996
5Epileptic encephalopathy (HP:0200134)4.40712797
6Visual hallucinations (HP:0002367)4.33234801
7Febrile seizures (HP:0002373)4.20370385
8Absence seizures (HP:0002121)4.00872623
9Dialeptic seizures (HP:0011146)3.68330269
10Acute necrotizing encephalopathy (HP:0006965)3.64327054
11Progressive cerebellar ataxia (HP:0002073)3.62609213
12Limb dystonia (HP:0002451)3.57807686
13Pheochromocytoma (HP:0002666)3.56371210
14Hyperventilation (HP:0002883)3.40055242
15Abnormal mitochondria in muscle tissue (HP:0008316)3.39069057
16Neuroendocrine neoplasm (HP:0100634)3.38211857
17Generalized tonic-clonic seizures (HP:0002069)3.34256365
18Progressive macrocephaly (HP:0004481)3.26199444
19Abnormal hair whorl (HP:0010721)3.24647287
20Gait imbalance (HP:0002141)3.05714597
21Mitochondrial inheritance (HP:0001427)2.95067209
22Progressive inability to walk (HP:0002505)2.94306439
23Broad-based gait (HP:0002136)2.92143292
24Polyphagia (HP:0002591)2.76559770
25Abnormal eating behavior (HP:0100738)2.74916938
26Congenital primary aphakia (HP:0007707)2.73558929
27Acute encephalopathy (HP:0006846)2.70001017
28Medial flaring of the eyebrow (HP:0010747)2.65869762
29Anxiety (HP:0000739)2.64727451
30Hypothermia (HP:0002045)2.62280712
31Truncal ataxia (HP:0002078)2.61054634
32Action tremor (HP:0002345)2.58016765
33Insidious onset (HP:0003587)2.57257425
34Termporal pattern (HP:0011008)2.57257425
35Ankle clonus (HP:0011448)2.56253607
36Supranuclear gaze palsy (HP:0000605)2.55179458
37Nephrogenic diabetes insipidus (HP:0009806)2.55132896
38Hemiparesis (HP:0001269)2.54933296
39Failure to thrive in infancy (HP:0001531)2.54825061
40Poor suck (HP:0002033)2.53910882
41Abnormality of the corticospinal tract (HP:0002492)2.53491049
42Gaze-evoked nystagmus (HP:0000640)2.51852889
43Degeneration of the lateral corticospinal tracts (HP:0002314)2.51812999
44Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.51812999
45Impaired vibration sensation in the lower limbs (HP:0002166)2.51564433
46Amblyopia (HP:0000646)2.50782282
47Genital tract atresia (HP:0001827)2.50616307
48Methylmalonic acidemia (HP:0002912)2.48853412
49Hepatocellular necrosis (HP:0001404)2.47293267
50Mutism (HP:0002300)2.46967772
51Vaginal atresia (HP:0000148)2.46624866
52Increased CSF lactate (HP:0002490)2.46583388
53Abnormality of glycolysis (HP:0004366)2.44621789
54Increased serum pyruvate (HP:0003542)2.44621789
55True hermaphroditism (HP:0010459)2.39588017
56Depression (HP:0000716)2.38647126
57Dysmetria (HP:0001310)2.37083653
58Epileptiform EEG discharges (HP:0011182)2.32003649
59Dysdiadochokinesis (HP:0002075)2.31375423
60Pancreatic fibrosis (HP:0100732)2.29893933
61Retinal dysplasia (HP:0007973)2.29360899
62Fetal akinesia sequence (HP:0001989)2.29346635
63Hypoglycemic coma (HP:0001325)2.28854555
64Specific learning disability (HP:0001328)2.28750085
65Muscular hypotonia of the trunk (HP:0008936)2.27383568
66Scanning speech (HP:0002168)2.26487159
67Inability to walk (HP:0002540)2.25938443
68Hyperinsulinemic hypoglycemia (HP:0000825)2.25022553
69Increased hepatocellular lipid droplets (HP:0006565)2.20331619
70EEG with generalized epileptiform discharges (HP:0011198)2.20016515
71Excessive salivation (HP:0003781)2.18151913
72Drooling (HP:0002307)2.18151913
73Poor eye contact (HP:0000817)2.18128202
74Intestinal atresia (HP:0011100)2.13599844
75Spastic gait (HP:0002064)2.11922584
76Leukodystrophy (HP:0002415)2.11058793
77Neurofibrillary tangles (HP:0002185)2.09128843
78Diplopia (HP:0000651)2.08728931
79Abnormality of binocular vision (HP:0011514)2.08728931
80Molar tooth sign on MRI (HP:0002419)2.07944554
81Abnormality of midbrain morphology (HP:0002418)2.07944554
82Esotropia (HP:0000565)2.07560554
83Urinary bladder sphincter dysfunction (HP:0002839)2.07457323
84Optic disc pallor (HP:0000543)2.07154269
85Hypsarrhythmia (HP:0002521)2.06582695
86Cerebral inclusion bodies (HP:0100314)2.05356707
87Delusions (HP:0000746)2.05261071
88Lipid accumulation in hepatocytes (HP:0006561)2.04515622
89Absent speech (HP:0001344)2.02966596
90Neoplasm of the peripheral nervous system (HP:0100007)2.02418766
91Generalized myoclonic seizures (HP:0002123)2.01235633
92Hypoventilation (HP:0002791)2.00711118
93Nephronophthisis (HP:0000090)1.99684603
94Hepatic necrosis (HP:0002605)1.99428736
95Pancreatic cysts (HP:0001737)1.98507009
96Urinary urgency (HP:0000012)1.98045907
97Abnormal social behavior (HP:0012433)1.97697981
98Impaired social interactions (HP:0000735)1.97697981
99Bradykinesia (HP:0002067)1.97062100
100Poor coordination (HP:0002370)1.94810622
101Akinesia (HP:0002304)1.94651287
102Hyperglycinemia (HP:0002154)1.93273810
1033-Methylglutaconic aciduria (HP:0003535)1.92403349
104Oligomenorrhea (HP:0000876)1.90734354
105Abnormality of the labia minora (HP:0012880)1.90515914
106Postaxial hand polydactyly (HP:0001162)1.89357317
107Agitation (HP:0000713)1.86241615
108Psychosis (HP:0000709)1.85218905
109Aplasia/Hypoplasia of the brainstem (HP:0007362)1.83498448
110Hypoplasia of the brainstem (HP:0002365)1.83498448
111Sensory axonal neuropathy (HP:0003390)1.83375788
112Spastic tetraplegia (HP:0002510)1.82829789
113Morphological abnormality of the pyramidal tract (HP:0002062)1.82709638
114X-linked dominant inheritance (HP:0001423)1.81914926
115Focal dystonia (HP:0004373)1.80973164
116Hypoglycemic seizures (HP:0002173)1.79934298
117Postural instability (HP:0002172)1.79609184
118Cerebral edema (HP:0002181)1.78471415
119Delayed gross motor development (HP:0002194)1.78045715
120Blue irides (HP:0000635)1.77531179
121Lower limb muscle weakness (HP:0007340)1.77377754
122Narrow nasal bridge (HP:0000446)1.77172504
123Decreased testicular size (HP:0008734)1.75744654
124Ketoacidosis (HP:0001993)1.75367270
125Renal Fanconi syndrome (HP:0001994)1.74721994
126Intention tremor (HP:0002080)1.73939831
127Atrophy/Degeneration involving motor neurons (HP:0007373)1.73555008
128Renal cortical cysts (HP:0000803)1.73162525
129Double outlet right ventricle (HP:0001719)1.71306494
130Congenital malformation of the right heart (HP:0011723)1.71306494
131Broad foot (HP:0001769)1.70927385
132Lissencephaly (HP:0001339)1.69401396
133Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.68909150
134Decreased activity of mitochondrial respiratory chain (HP:0008972)1.68909150
135Type II lissencephaly (HP:0007260)1.68552517
136Abnormality of aromatic amino acid family metabolism (HP:0004338)1.68392013
137Methylmalonic aciduria (HP:0012120)1.68163558
138Aplasia/Hypoplasia of the lens (HP:0008063)1.67317642
139Optic nerve hypoplasia (HP:0000609)1.66646118
140Exercise-induced muscle cramps (HP:0003710)1.64296682
141Status epilepticus (HP:0002133)1.63292588
142Large for gestational age (HP:0001520)1.62569567
143Amyotrophic lateral sclerosis (HP:0007354)1.61032616
144Abnormality of vitamin B metabolism (HP:0004340)1.60312205
145Glycosuria (HP:0003076)1.59893009

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K123.79725100
2CASK3.62416990
3NTRK33.56805827
4MAP3K43.21954012
5MAP2K73.15406376
6TRIM282.82622919
7MAP3K92.64390347
8MINK12.57950232
9MARK12.55875461
10EPHA42.44981876
11MAP4K22.15925272
12PLK22.14126675
13GRK52.02994451
14ARAF1.98777209
15CDK191.97592517
16MAP2K41.94229365
17FRK1.88452438
18OXSR11.85120686
19PNCK1.83496610
20MAPK131.66618038
21NTRK11.66228736
22TNIK1.64075167
23NTRK21.53552322
24MST41.37033419
25EIF2AK31.35422198
26PAK61.34845209
27RIPK41.32520705
28DAPK11.27242704
29CDK51.27067661
30NME11.26809056
31KSR21.26326335
32STK391.22737968
33BCR1.21781088
34MAPKAPK51.20634606
35DAPK21.20317096
36PRKCG1.18099424
37TSSK61.17729622
38CAMK2A1.15661322
39GRK71.15416384
40KSR11.14135163
41UHMK11.13271242
42CSNK1G21.12934990
43SIK31.11622168
44BCKDK1.10524996
45BMPR1B1.10069416
46LIMK11.09689447
47CAMK2B1.09017159
48CDK141.06313599
49GRK11.02620451
50CAMKK21.02090502
51SGK2231.01733205
52SGK4941.01733205
53CDK181.00238918
54BMPR20.97674285
55FGFR20.96887455
56PRPF4B0.95942313
57CSNK1G30.94544988
58SRPK10.93696658
59CDK150.93162113
60PHKG10.90553364
61PHKG20.90553364
62ADRBK20.89574245
63STK38L0.89155865
64PRKCE0.88660651
65NEK10.87938961
66LATS20.87367865
67FES0.85900534
68CDK11A0.81620824
69MKNK20.81004008
70CCNB10.80264256
71EIF2AK10.80075117
72CAMK2D0.78198552
73PDK20.77069719
74PBK0.76603860
75PTK2B0.75959802
76WNK30.75410891
77BUB10.72819752
78STK160.72279693
79EPHA30.70457616
80TESK10.70137088
81DYRK1A0.69665762
82CAMKK10.68976168
83BRAF0.67590345
84CAMK2G0.67527300
85NEK60.66761065
86AKT30.66213151
87SGK20.66101173
88MAP3K20.66035419
89PDK40.65077040
90PDK30.65077040
91MUSK0.64282684
92PAK30.63938119
93WEE10.63067592
94CDK80.62735433
95WNK40.61945224
96NUAK10.60518581
97ADRBK10.60136124
98MKNK10.59567506
99INSRR0.59408329
100SIK20.58516321
101ROCK20.58053672
102PRKD30.57862490
103MAP3K60.57370316
104PLK40.57159259
105CDK30.55874664
106RAF10.55763863
107RPS6KA40.55361070
108RET0.53125083
109PINK10.50781186
110FGR0.50659490
111MYLK0.50297613
112MAP2K10.50012596
113DYRK30.49723474
114ERBB40.48175272
115DYRK20.47489833
116FER0.47483017
117CSNK1G10.47216340
118CSNK1A10.47205302
119CSNK1E0.47144207
120ZAK0.45383569
121CAMK10.45067500
122WNK10.44569711
123PKN10.44468453
124CSNK1A1L0.43615240
125PLK30.41468299
126SGK10.40931455
127BRSK10.40333300
128PRKACA0.40114479
129PLK10.39235180
130ERBB30.38790046
131VRK10.37921515
132PRKG10.37657933
133LMTK20.37418852
134CSNK1D0.36525605
135PRKACB0.35150807

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.89595587
2Synaptic vesicle cycle_Homo sapiens_hsa047213.85585233
3Collecting duct acid secretion_Homo sapiens_hsa049663.13267536
4Oxidative phosphorylation_Homo sapiens_hsa001902.93218981
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.75049260
6GABAergic synapse_Homo sapiens_hsa047272.71857764
7Morphine addiction_Homo sapiens_hsa050322.38824337
8Circadian entrainment_Homo sapiens_hsa047132.34639451
9Parkinsons disease_Homo sapiens_hsa050122.31777063
10Glutamatergic synapse_Homo sapiens_hsa047242.26616974
11Olfactory transduction_Homo sapiens_hsa047402.23399202
12Amphetamine addiction_Homo sapiens_hsa050312.23088949
13Long-term potentiation_Homo sapiens_hsa047202.20672869
14Dopaminergic synapse_Homo sapiens_hsa047282.13472377
15Vibrio cholerae infection_Homo sapiens_hsa051102.11376331
16Serotonergic synapse_Homo sapiens_hsa047262.01780299
17Alzheimers disease_Homo sapiens_hsa050101.95632662
18Taste transduction_Homo sapiens_hsa047421.93100458
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.83951161
20Propanoate metabolism_Homo sapiens_hsa006401.83223459
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.81183884
22Salivary secretion_Homo sapiens_hsa049701.74580337
23Long-term depression_Homo sapiens_hsa047301.71399320
24Vitamin B6 metabolism_Homo sapiens_hsa007501.66981209
25Cocaine addiction_Homo sapiens_hsa050301.65641889
26Cholinergic synapse_Homo sapiens_hsa047251.64906181
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.62293718
28Insulin secretion_Homo sapiens_hsa049111.60515426
29Huntingtons disease_Homo sapiens_hsa050161.54730558
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.53719140
31Cardiac muscle contraction_Homo sapiens_hsa042601.52336452
32Renin secretion_Homo sapiens_hsa049241.48375041
33Steroid biosynthesis_Homo sapiens_hsa001001.43019635
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.41858452
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.41138893
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.40198822
37Gastric acid secretion_Homo sapiens_hsa049711.40164270
38Calcium signaling pathway_Homo sapiens_hsa040201.32724212
39Folate biosynthesis_Homo sapiens_hsa007901.29508042
40Oxytocin signaling pathway_Homo sapiens_hsa049211.23485579
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21145463
42Gap junction_Homo sapiens_hsa045401.21045086
43Aldosterone synthesis and secretion_Homo sapiens_hsa049251.20666160
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.19836272
45Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.16473035
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13390374
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08886057
48Peroxisome_Homo sapiens_hsa041461.07784806
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06220741
50GnRH signaling pathway_Homo sapiens_hsa049121.05368000
51Phototransduction_Homo sapiens_hsa047441.05193848
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03600473
53Axon guidance_Homo sapiens_hsa043601.03419587
54Basal transcription factors_Homo sapiens_hsa030220.97553491
55Rheumatoid arthritis_Homo sapiens_hsa053230.95674832
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.94199539
57Fatty acid metabolism_Homo sapiens_hsa012120.92879469
58Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92713274
59cAMP signaling pathway_Homo sapiens_hsa040240.88342048
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87978685
61Sulfur metabolism_Homo sapiens_hsa009200.86756856
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84931147
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81785090
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81450937
65Oocyte meiosis_Homo sapiens_hsa041140.80808620
66Phagosome_Homo sapiens_hsa041450.79341537
67Estrogen signaling pathway_Homo sapiens_hsa049150.77370741
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.76135435
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74754374
70Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74747687
71Melanogenesis_Homo sapiens_hsa049160.74208141
72ErbB signaling pathway_Homo sapiens_hsa040120.74182490
73Arginine and proline metabolism_Homo sapiens_hsa003300.73713339
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.71636446
75cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70203688
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.69855134
77beta-Alanine metabolism_Homo sapiens_hsa004100.67738876
78RNA degradation_Homo sapiens_hsa030180.67535143
79Alcoholism_Homo sapiens_hsa050340.66436621
80Tryptophan metabolism_Homo sapiens_hsa003800.64598688
812-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.60441067
82Metabolic pathways_Homo sapiens_hsa011000.60016533
83Glioma_Homo sapiens_hsa052140.59516471
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58691999
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58434746
86Selenocompound metabolism_Homo sapiens_hsa004500.57269939
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.56817780
88Thyroid hormone synthesis_Homo sapiens_hsa049180.56178873
89Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56010125
90Pancreatic secretion_Homo sapiens_hsa049720.55795115
91Type I diabetes mellitus_Homo sapiens_hsa049400.55512629
92Pyruvate metabolism_Homo sapiens_hsa006200.54298661
93Fatty acid degradation_Homo sapiens_hsa000710.53922688
94RNA polymerase_Homo sapiens_hsa030200.53374932
95Ras signaling pathway_Homo sapiens_hsa040140.52585008
96Butanoate metabolism_Homo sapiens_hsa006500.49724900
97MAPK signaling pathway_Homo sapiens_hsa040100.49688790
98Nitrogen metabolism_Homo sapiens_hsa009100.49356875
99Carbon metabolism_Homo sapiens_hsa012000.46999767
100Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46847570
101Ether lipid metabolism_Homo sapiens_hsa005650.45709615
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45606246
103Fatty acid elongation_Homo sapiens_hsa000620.45433215
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45359069
105Dilated cardiomyopathy_Homo sapiens_hsa054140.44611176
106Caffeine metabolism_Homo sapiens_hsa002320.44459507
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44341732
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44123331
109Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43738674
110Type II diabetes mellitus_Homo sapiens_hsa049300.43417455
111Protein export_Homo sapiens_hsa030600.43147903
112Phospholipase D signaling pathway_Homo sapiens_hsa040720.42621595
113Hedgehog signaling pathway_Homo sapiens_hsa043400.42335470
114Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.41733845
115Glutathione metabolism_Homo sapiens_hsa004800.41431666
116Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.41157712
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.41014616
118Hippo signaling pathway_Homo sapiens_hsa043900.39142830
119Retinol metabolism_Homo sapiens_hsa008300.38342283
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37780285
121Non-homologous end-joining_Homo sapiens_hsa034500.37173772
122Choline metabolism in cancer_Homo sapiens_hsa052310.35900950
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.34642989
124Endocytosis_Homo sapiens_hsa041440.33558490
125Renal cell carcinoma_Homo sapiens_hsa052110.32442080
126Regulation of autophagy_Homo sapiens_hsa041400.31798521
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30851009
128Rap1 signaling pathway_Homo sapiens_hsa040150.29863632
129Dorso-ventral axis formation_Homo sapiens_hsa043200.29805631
130Glucagon signaling pathway_Homo sapiens_hsa049220.28655081
131Ovarian steroidogenesis_Homo sapiens_hsa049130.28330705
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27509409
133Proteasome_Homo sapiens_hsa030500.27405329
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.26676626
135Circadian rhythm_Homo sapiens_hsa047100.26160985
136Inositol phosphate metabolism_Homo sapiens_hsa005620.26055213
137Melanoma_Homo sapiens_hsa052180.25917644
138Wnt signaling pathway_Homo sapiens_hsa043100.23090401
139Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.22373194
140Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21967093
141Neurotrophin signaling pathway_Homo sapiens_hsa047220.19647383

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »