SCRN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.83375195
2synaptic vesicle maturation (GO:0016188)5.71179804
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.48799622
4locomotory exploration behavior (GO:0035641)5.42220561
5synaptic vesicle exocytosis (GO:0016079)5.33212282
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.20739027
7vocalization behavior (GO:0071625)5.07086214
8regulation of synaptic vesicle exocytosis (GO:2000300)5.05432391
9glutamate secretion (GO:0014047)4.84760063
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.81626207
11protein localization to synapse (GO:0035418)4.62414204
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.56039695
13layer formation in cerebral cortex (GO:0021819)4.53111689
14neuron cell-cell adhesion (GO:0007158)4.51590671
15regulation of glutamate receptor signaling pathway (GO:1900449)4.46982695
16regulation of synapse structural plasticity (GO:0051823)4.40254622
17regulation of synaptic vesicle transport (GO:1902803)4.38852268
18neurotransmitter secretion (GO:0007269)4.34694897
19exploration behavior (GO:0035640)4.30418797
20ionotropic glutamate receptor signaling pathway (GO:0035235)4.12501528
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.09293323
22neuronal action potential propagation (GO:0019227)4.08190434
23regulation of neuronal synaptic plasticity (GO:0048168)4.05662064
24synaptic transmission, glutamatergic (GO:0035249)3.93006442
25dendritic spine morphogenesis (GO:0060997)3.91757576
26gamma-aminobutyric acid transport (GO:0015812)3.89112850
27neuron-neuron synaptic transmission (GO:0007270)3.84421935
28neurotransmitter-gated ion channel clustering (GO:0072578)3.83301903
29cellular potassium ion homeostasis (GO:0030007)3.81522340
30glutamate receptor signaling pathway (GO:0007215)3.81429465
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.76564574
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.68295363
33membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.65875919
34positive regulation of synapse maturation (GO:0090129)3.61659520
35long-term memory (GO:0007616)3.59548195
36positive regulation of membrane potential (GO:0045838)3.57291116
37neurotransmitter transport (GO:0006836)3.56402086
38transmission of nerve impulse (GO:0019226)3.55965522
39neuron recognition (GO:0008038)3.52604990
40proline transport (GO:0015824)3.52472320
41prepulse inhibition (GO:0060134)3.49172113
42synaptic vesicle endocytosis (GO:0048488)3.48930125
43sodium ion export (GO:0071436)3.48777895
44amino acid import (GO:0043090)3.45879249
45positive regulation of synaptic transmission, GABAergic (GO:0032230)3.45746611
46regulation of excitatory postsynaptic membrane potential (GO:0060079)3.44510987
47dendrite morphogenesis (GO:0048813)3.44054939
48activation of protein kinase A activity (GO:0034199)3.43338139
49gamma-aminobutyric acid signaling pathway (GO:0007214)3.41633757
50auditory behavior (GO:0031223)3.40699669
51regulation of neurotransmitter secretion (GO:0046928)3.39702641
52neuromuscular process controlling balance (GO:0050885)3.35793207
53positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.32057159
54postsynaptic membrane organization (GO:0001941)3.31580032
55cerebellar Purkinje cell differentiation (GO:0021702)3.31218289
56regulation of postsynaptic membrane potential (GO:0060078)3.31173615
57response to auditory stimulus (GO:0010996)3.30825206
58positive regulation of dendritic spine morphogenesis (GO:0061003)3.28264587
59regulation of dendritic spine morphogenesis (GO:0061001)3.27733429
60long-term synaptic potentiation (GO:0060291)3.26767741
61axonal fasciculation (GO:0007413)3.26590012
62regulation of neurotransmitter levels (GO:0001505)3.26191857
63regulation of synaptic transmission, glutamatergic (GO:0051966)3.25529762
64regulation of synaptic plasticity (GO:0048167)3.22690180
65positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.22655911
66G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.22004751
67regulation of neurotransmitter transport (GO:0051588)3.21667625
68mating behavior (GO:0007617)3.21363353
69regulation of vesicle fusion (GO:0031338)3.19785226
70cerebellar granule cell differentiation (GO:0021707)3.19574855
71membrane hyperpolarization (GO:0060081)3.18640495
72synapse assembly (GO:0007416)3.17250277
73cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.14009787
74positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.12184972
75L-amino acid import (GO:0043092)3.12012393
76innervation (GO:0060384)3.11681913
77establishment of mitochondrion localization (GO:0051654)3.11624775
78negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.10365300
79glycine transport (GO:0015816)3.10194209
80neuromuscular process controlling posture (GO:0050884)3.09923254
81response to pheromone (GO:0019236)3.09854192
82cell communication by electrical coupling (GO:0010644)3.09562023
83cytoskeletal anchoring at plasma membrane (GO:0007016)3.07434554
84positive regulation of neurotransmitter transport (GO:0051590)3.05533421
85neuronal ion channel clustering (GO:0045161)3.04685728
86cell migration in hindbrain (GO:0021535)3.04071894
87membrane depolarization during action potential (GO:0086010)3.02281132
88central nervous system myelination (GO:0022010)3.00446026
89axon ensheathment in central nervous system (GO:0032291)3.00446026
90vesicle transport along microtubule (GO:0047496)2.99593056
91regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.98891847
92presynaptic membrane assembly (GO:0097105)2.98049663
93behavioral response to cocaine (GO:0048148)2.96717169
94negative regulation of synaptic transmission, GABAergic (GO:0032229)2.96461418
95regulation of voltage-gated calcium channel activity (GO:1901385)2.94820313
96membrane depolarization (GO:0051899)2.94118058
97adult walking behavior (GO:0007628)2.93216976
98learning (GO:0007612)2.92160041
99striatum development (GO:0021756)2.90574285
100axon extension (GO:0048675)2.89782075
101synapse organization (GO:0050808)2.89475779
102positive regulation of neurotransmitter secretion (GO:0001956)2.88764542
103synaptic transmission (GO:0007268)2.86624404
104neuromuscular process (GO:0050905)2.85337967
105positive regulation of synaptic transmission (GO:0050806)2.85111054
106negative regulation of dendrite morphogenesis (GO:0050774)2.84502863
107potassium ion homeostasis (GO:0055075)2.84412995
108presynaptic membrane organization (GO:0097090)2.84210041
109negative regulation of cytosolic calcium ion concentration (GO:0051481)2.84190967
110cellular sodium ion homeostasis (GO:0006883)2.80986003
111cerebral cortex radially oriented cell migration (GO:0021799)2.80291214
112cerebellar Purkinje cell layer development (GO:0021680)2.78189636
113membrane assembly (GO:0071709)2.77325137
114positive regulation of dendritic spine development (GO:0060999)2.75622337
115positive regulation of synapse assembly (GO:0051965)2.73310429
116suckling behavior (GO:0001967)2.67184323
117neuron projection extension (GO:1990138)2.65611246
118establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.62601103
119mitochondrion transport along microtubule (GO:0047497)2.62601103
120apical protein localization (GO:0045176)2.62368792
121astrocyte development (GO:0014002)2.57052703
122central nervous system projection neuron axonogenesis (GO:0021952)2.55991622
123potassium ion import (GO:0010107)2.50766511
124G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.48940796
125regulation of dendrite morphogenesis (GO:0048814)2.48744196
126dendritic spine organization (GO:0097061)2.47919158
127pyrimidine nucleobase catabolic process (GO:0006208)2.46455165
128positive regulation of dendrite development (GO:1900006)2.42590615
129regulation of respiratory system process (GO:0044065)2.42001009
130protein retention in ER lumen (GO:0006621)2.40664422
131adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.37257940
132axon cargo transport (GO:0008088)2.36197264
133mechanosensory behavior (GO:0007638)2.35566291
134acidic amino acid transport (GO:0015800)2.34245288

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.42098643
2GBX2_23144817_ChIP-Seq_PC3_Human3.40016553
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.08929283
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04472817
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02244726
6REST_21632747_ChIP-Seq_MESCs_Mouse2.74176808
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.72302512
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.72302512
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.67307000
10DROSHA_22980978_ChIP-Seq_HELA_Human2.57976421
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.57868678
12* RARB_27405468_Chip-Seq_BRAIN_Mouse2.53357233
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52715300
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.52568746
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51359164
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.50643587
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.46299071
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.39131351
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.37689492
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.30857377
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.28389237
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.27157656
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.24005009
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.19761264
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.11967802
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.07543258
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04500345
28TRIM28_21343339_ChIP-Seq_HEK293_Human1.95977254
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.95333484
30EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.93970466
31AR_21572438_ChIP-Seq_LNCaP_Human1.88226227
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.79584850
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76345077
34* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.73462628
35WT1_19549856_ChIP-ChIP_CCG9911_Human1.59428275
36TAF15_26573619_Chip-Seq_HEK293_Human1.57891778
37SMAD4_21799915_ChIP-Seq_A2780_Human1.57459441
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55857647
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.54882551
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.54297115
41SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.53395670
42SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.53339695
43ZFP281_27345836_Chip-Seq_ESCs_Mouse1.52086775
44ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.51131983
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.48042494
46DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.43358038
47PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39080712
48ZNF274_21170338_ChIP-Seq_K562_Hela1.38222960
49NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.35892914
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.35773869
51PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.33522768
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31751963
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31462769
54THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31043304
55* SOX2_21211035_ChIP-Seq_LN229_Gbm1.30780999
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.30357018
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.29392724
58EP300_21415370_ChIP-Seq_HL-1_Mouse1.29065334
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.27599606
60RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.27399757
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.26063939
62P300_19829295_ChIP-Seq_ESCs_Human1.25652462
63STAT3_23295773_ChIP-Seq_U87_Human1.22911009
64* AR_19668381_ChIP-Seq_PC3_Human1.22565342
65* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.21464115
66SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21450178
67ISL1_27105846_Chip-Seq_CPCs_Mouse1.20968672
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19763691
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19449593
70* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18621269
71ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.18162813
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.18033971
73P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17828482
74DNAJC2_21179169_ChIP-ChIP_NT2_Human1.17826673
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17574532
76SOX9_26525672_Chip-Seq_HEART_Mouse1.15956989
77PIAS1_25552417_ChIP-Seq_VCAP_Human1.15642525
78GATA1_26923725_Chip-Seq_HPCs_Mouse1.15163807
79AR_25329375_ChIP-Seq_VCAP_Human1.15087481
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13710849
81RNF2_27304074_Chip-Seq_NSC_Mouse1.10947568
82SMAD_19615063_ChIP-ChIP_OVARY_Human1.09898692
83TP53_20018659_ChIP-ChIP_R1E_Mouse1.09439803
84CLOCK_20551151_ChIP-Seq_293T_Human1.09218830
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09087851
86WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.08809990
87KDM2B_26808549_Chip-Seq_K562_Human1.08368738
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07011055
89TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06875187
90* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06835501
91ZFP281_18757296_ChIP-ChIP_E14_Mouse1.06181974
92IGF1R_20145208_ChIP-Seq_DFB_Human1.06141263
93* TCF4_23295773_ChIP-Seq_U87_Human1.05212785
94POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05150446
95ARNT_22903824_ChIP-Seq_MCF-7_Human1.04286595
96AHR_22903824_ChIP-Seq_MCF-7_Human1.03835415
97TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02642322
98MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01652478
99SMAD3_21741376_ChIP-Seq_ESCs_Human1.01050745
100STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.00994640
101TBX3_20139965_ChIP-Seq_MESCs_Mouse1.00797493
102* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.00714433
103* CDX2_19796622_ChIP-Seq_MESCs_Mouse0.99805079
104TBX3_20139965_ChIP-Seq_ESCs_Mouse0.98806231
105* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98659587
106TP53_18474530_ChIP-ChIP_U2OS_Human0.96507299
107TP53_16413492_ChIP-PET_HCT116_Human0.96483899
108CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96198473
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96051131
110SMAD4_21741376_ChIP-Seq_HESCs_Human0.95768217
111POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.95280129
112VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94578011
113RUNX2_22187159_ChIP-Seq_PCA_Human0.93841569
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92768548
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92368834
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91871783
117NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.91602289
118OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.91553538
119POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.91335689
120POU3F2_20337985_ChIP-ChIP_501MEL_Human0.90559391
121KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.88896656
122SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.87972512
123NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.87960739
124ESR2_21235772_ChIP-Seq_MCF-7_Human0.87236797
125ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.86769492
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86103185
127SMAD3_21741376_ChIP-Seq_HESCs_Human0.85830069
128GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85767781
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85226370
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85226370
131PRDM14_20953172_ChIP-Seq_ESCs_Human0.85195533
132RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.84434078
133PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83886652
134* TET1_21490601_ChIP-Seq_MESCs_Mouse0.82659937

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.86066129
2MP0003880_abnormal_central_pattern4.35845749
3MP0003635_abnormal_synaptic_transmissio3.92304612
4MP0004270_analgesia3.60051390
5MP0009745_abnormal_behavioral_response3.19091780
6MP0002063_abnormal_learning/memory/cond3.13125488
7MP0009046_muscle_twitch3.11939785
8MP0002064_seizures3.01021740
9MP0005423_abnormal_somatic_nervous2.94338535
10MP0002822_catalepsy2.90261817
11MP0001968_abnormal_touch/_nociception2.81503149
12MP0002734_abnormal_mechanical_nocicepti2.70249151
13MP0002572_abnormal_emotion/affect_behav2.65470926
14MP0002272_abnormal_nervous_system2.57890714
15MP0001486_abnormal_startle_reflex2.57029934
16MP0002736_abnormal_nociception_after2.06282305
17MP0009780_abnormal_chondrocyte_physiolo2.04814398
18MP0002735_abnormal_chemical_nociception2.04066369
19MP0000778_abnormal_nervous_system2.02450341
20MP0002733_abnormal_thermal_nociception2.01888772
21MP0001501_abnormal_sleep_pattern1.99020922
22MP0002067_abnormal_sensory_capabilities1.97538893
23MP0001984_abnormal_olfaction1.94864582
24MP0002184_abnormal_innervation1.94625433
25MP0001440_abnormal_grooming_behavior1.94493698
26MP0001970_abnormal_pain_threshold1.90251280
27MP0008569_lethality_at_weaning1.88464913
28MP0002909_abnormal_adrenal_gland1.83913742
29MP0002557_abnormal_social/conspecific_i1.78994167
30MP0004924_abnormal_behavior1.78161905
31MP0005386_behavior/neurological_phenoty1.78161905
32MP0004811_abnormal_neuron_physiology1.77042923
33MP0004858_abnormal_nervous_system1.75925783
34MP0005646_abnormal_pituitary_gland1.72889110
35MP0003329_amyloid_beta_deposits1.70923640
36MP0000955_abnormal_spinal_cord1.69075067
37MP0006276_abnormal_autonomic_nervous1.61326048
38MP0004885_abnormal_endolymph1.60907629
39MP0003705_abnormal_hypodermis_morpholog1.58600337
40MP0003879_abnormal_hair_cell1.57872154
41MP0003123_paternal_imprinting1.55337496
42MP0002882_abnormal_neuron_morphology1.54587959
43MP0000537_abnormal_urethra_morphology1.53389779
44MP0005645_abnormal_hypothalamus_physiol1.47182590
45MP0001529_abnormal_vocalization1.46447759
46MP0002066_abnormal_motor_capabilities/c1.42711035
47MP0001502_abnormal_circadian_rhythm1.40871185
48MP0008438_abnormal_cutaneous_collagen1.39888419
49MP0005551_abnormal_eye_electrophysiolog1.39662940
50MP0000534_abnormal_ureter_morphology1.37918637
51MP0003787_abnormal_imprinting1.36411785
52MP0003122_maternal_imprinting1.34533017
53MP0005257_abnormal_intraocular_pressure1.34211609
54MP0003283_abnormal_digestive_organ1.33212745
55MP0004142_abnormal_muscle_tone1.29968146
56MP0001905_abnormal_dopamine_level1.25331959
57MP0003633_abnormal_nervous_system1.22786080
58MP0002152_abnormal_brain_morphology1.18689117
59MP0003942_abnormal_urinary_system1.17119156
60MP0000569_abnormal_digit_pigmentation1.16802609
61MP0004272_abnormal_basement_membrane1.16357250
62MP0005248_abnormal_Harderian_gland1.14156536
63MP0002229_neurodegeneration1.13716817
64MP0004742_abnormal_vestibular_system1.12439394
65MP0003121_genomic_imprinting1.12049052
66MP0003385_abnormal_body_wall1.11562493
67MP0005394_taste/olfaction_phenotype1.10241852
68MP0005499_abnormal_olfactory_system1.10241852
69MP0003634_abnormal_glial_cell1.09512786
70MP0002090_abnormal_vision1.09162726
71MP0000013_abnormal_adipose_tissue1.06941781
72MP0003631_nervous_system_phenotype1.06773188
73MP0000566_synostosis1.06394041
74MP0001958_emphysema1.06087508
75MP0006072_abnormal_retinal_apoptosis1.05717537
76MP0001188_hyperpigmentation1.05557390
77MP0000631_abnormal_neuroendocrine_gland1.04264490
78MP0010368_abnormal_lymphatic_system0.99616743
79MP0004145_abnormal_muscle_electrophysio0.99154906
80MP0000920_abnormal_myelination0.96874672
81MP0009053_abnormal_anal_canal0.95430433
82MP0002752_abnormal_somatic_nervous0.95396804
83MP0002877_abnormal_melanocyte_morpholog0.94402118
84MP0000428_abnormal_craniofacial_morphol0.93644009
85MP0002069_abnormal_eating/drinking_beha0.93438314
86MP0001346_abnormal_lacrimal_gland0.93009035
87MP0000751_myopathy0.92213299
88MP0001177_atelectasis0.91551379
89MP0010030_abnormal_orbit_morphology0.91460218
90MP0005187_abnormal_penis_morphology0.91280291
91MP0002638_abnormal_pupillary_reflex0.90110766
92MP0003690_abnormal_glial_cell0.89818113
93MP0001963_abnormal_hearing_physiology0.88837567
94MP0000462_abnormal_digestive_system0.87280196
95MP0001348_abnormal_lacrimal_gland0.86819043
96MP0003632_abnormal_nervous_system0.86096423
97MP0000579_abnormal_nail_morphology0.85337806
98MP0001485_abnormal_pinna_reflex0.84633888
99MP0002081_perinatal_lethality0.84610561
100MP0004233_abnormal_muscle_weight0.84396287
101MP0010386_abnormal_urinary_bladder0.83726449
102MP0008872_abnormal_physiological_respon0.82267913
103MP0001299_abnormal_eye_distance/0.81529408
104MP0002233_abnormal_nose_morphology0.80838138
105MP0003119_abnormal_digestive_system0.80197254
106MP0004085_abnormal_heartbeat0.79859233
107MP0002697_abnormal_eye_size0.79858046
108MP0008961_abnormal_basal_metabolism0.79653813
109MP0005623_abnormal_meninges_morphology0.78676739
110MP0003115_abnormal_respiratory_system0.77585294
111MP0000762_abnormal_tongue_morphology0.77496088
112MP0003755_abnormal_palate_morphology0.76756509
113MP0006292_abnormal_olfactory_placode0.74891054
114MP0000049_abnormal_middle_ear0.74839396
115MP0005253_abnormal_eye_physiology0.74664954
116MP0002249_abnormal_larynx_morphology0.74512331
117MP0002089_abnormal_postnatal_growth/wei0.73994729
118MP0003935_abnormal_craniofacial_develop0.73370060
119MP0004043_abnormal_pH_regulation0.71315852
120MP0002116_abnormal_craniofacial_bone0.71149423
121MP0002653_abnormal_ependyma_morphology0.70917615
122MP0003937_abnormal_limbs/digits/tail_de0.69127421
123MP0003137_abnormal_impulse_conducting0.68540074
124MP0008874_decreased_physiological_sensi0.68170792
125MP0003861_abnormal_nervous_system0.67669476
126MP0005535_abnormal_body_temperature0.66586300
127MP0005409_darkened_coat_color0.66185132
128MP0002234_abnormal_pharynx_morphology0.64126156
129MP0000026_abnormal_inner_ear0.61602096
130MP0000604_amyloidosis0.61204193
131MP0001943_abnormal_respiration0.61017505
132MP0004215_abnormal_myocardial_fiber0.56392117
133MP0002751_abnormal_autonomic_nervous0.56314922
134MP0010769_abnormal_survival0.55122284
135MP0008789_abnormal_olfactory_epithelium0.54925954
136MP0002082_postnatal_lethality0.54026968
137MP0010770_preweaning_lethality0.54026968

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.43829904
2Focal motor seizures (HP:0011153)6.27548887
3Focal seizures (HP:0007359)5.12912642
4Visual hallucinations (HP:0002367)4.90325257
5Epileptic encephalopathy (HP:0200134)4.49117225
6Progressive cerebellar ataxia (HP:0002073)4.26710921
7Atonic seizures (HP:0010819)4.14302641
8Action tremor (HP:0002345)4.10268870
9Febrile seizures (HP:0002373)3.86699124
10Absence seizures (HP:0002121)3.78655520
11Ankle clonus (HP:0011448)3.74733037
12Supranuclear gaze palsy (HP:0000605)3.67679625
13Dialeptic seizures (HP:0011146)3.40430336
14Generalized tonic-clonic seizures (HP:0002069)3.38406807
15Depression (HP:0000716)3.16437658
16Broad-based gait (HP:0002136)3.16320031
17Mutism (HP:0002300)3.10797639
18Dysdiadochokinesis (HP:0002075)3.09819008
19Poor eye contact (HP:0000817)3.06372947
20Gaze-evoked nystagmus (HP:0000640)3.04288571
21Urinary bladder sphincter dysfunction (HP:0002839)2.94468145
22Truncal ataxia (HP:0002078)2.92204099
23Limb dystonia (HP:0002451)2.90944189
24Impaired vibration sensation in the lower limbs (HP:0002166)2.90496957
25Anxiety (HP:0000739)2.89359007
26Abnormal eating behavior (HP:0100738)2.86047815
27Dysmetria (HP:0001310)2.83631866
28Hemiparesis (HP:0001269)2.75688062
29Protrusio acetabuli (HP:0003179)2.75122308
30Abnormal social behavior (HP:0012433)2.75005121
31Impaired social interactions (HP:0000735)2.75005121
32Genetic anticipation (HP:0003743)2.74963688
33Arterial tortuosity (HP:0005116)2.73130752
34Scanning speech (HP:0002168)2.72625828
35Spastic gait (HP:0002064)2.69875040
36Torticollis (HP:0000473)2.67942841
37Postural instability (HP:0002172)2.67167888
38Premature rupture of membranes (HP:0001788)2.66734817
39Pheochromocytoma (HP:0002666)2.65537406
40Vascular tortuosity (HP:0004948)2.64516249
41Papilledema (HP:0001085)2.64191673
42Neurofibrillary tangles (HP:0002185)2.62451387
43Abnormality of the corticospinal tract (HP:0002492)2.60435583
44Hyperacusis (HP:0010780)2.57862116
45Megalencephaly (HP:0001355)2.57837526
46Drooling (HP:0002307)2.57157773
47Excessive salivation (HP:0003781)2.57157773
48Termporal pattern (HP:0011008)2.54317327
49Insidious onset (HP:0003587)2.54317327
50Urinary urgency (HP:0000012)2.51169046
51Intention tremor (HP:0002080)2.50269534
52Epileptiform EEG discharges (HP:0011182)2.48247189
53EEG with generalized epileptiform discharges (HP:0011198)2.47970468
54Turricephaly (HP:0000262)2.44430797
55Neonatal short-limb short stature (HP:0008921)2.44028780
56Cerebral inclusion bodies (HP:0100314)2.43827523
57Shallow orbits (HP:0000586)2.41204143
58Hyperventilation (HP:0002883)2.39888299
59Abnormality of the lower motor neuron (HP:0002366)2.39091063
60Impaired smooth pursuit (HP:0007772)2.38512644
61Amblyopia (HP:0000646)2.38475285
62Focal dystonia (HP:0004373)2.37769409
63Hypsarrhythmia (HP:0002521)2.34157651
64Fetal akinesia sequence (HP:0001989)2.32769958
65Lower limb muscle weakness (HP:0007340)2.31566098
66Agitation (HP:0000713)2.30776496
67Progressive inability to walk (HP:0002505)2.29600602
68Abnormality of binocular vision (HP:0011514)2.27973577
69Diplopia (HP:0000651)2.27973577
70Bowel diverticulosis (HP:0005222)2.25845979
71Aplasia involving bones of the extremities (HP:0009825)2.25535273
72Aplasia involving bones of the upper limbs (HP:0009823)2.25535273
73Aplasia of the phalanges of the hand (HP:0009802)2.25535273
74Neuroendocrine neoplasm (HP:0100634)2.23970735
75Vertebral arch anomaly (HP:0008438)2.23147948
76Polyphagia (HP:0002591)2.22619781
77Hemiplegia (HP:0002301)2.21692095
78Stereotypic behavior (HP:0000733)2.21581202
79Bradykinesia (HP:0002067)2.19532611
80Craniofacial dystonia (HP:0012179)2.19190579
81Overriding aorta (HP:0002623)2.17977494
82Obstructive sleep apnea (HP:0002870)2.15754354
83Bladder diverticulum (HP:0000015)2.14954148
84Abnormality of ocular smooth pursuit (HP:0000617)2.13930745
85Central scotoma (HP:0000603)2.11365753
86Clonus (HP:0002169)2.07162288
87Bronchomalacia (HP:0002780)2.07015285
88Akinesia (HP:0002304)2.05501052
89Renal duplication (HP:0000075)2.04807631
90Ventricular fibrillation (HP:0001663)2.04720273
91Abnormality of dentin (HP:0010299)2.04526576
92Elfin facies (HP:0004428)2.03862773
93Hammertoe (HP:0001765)2.02956170
94Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.02881119
95Dysmetric saccades (HP:0000641)2.01849030
96Hepatoblastoma (HP:0002884)2.01170787
97Insomnia (HP:0100785)2.00632348
98Atrophic scars (HP:0001075)1.98137829
99Amyotrophic lateral sclerosis (HP:0007354)1.97514562
100Pointed chin (HP:0000307)1.97344274
101Absent speech (HP:0001344)1.95432112
102Blue irides (HP:0000635)1.93462321
103Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.93383780
104Gait imbalance (HP:0002141)1.93144384
105Specific learning disability (HP:0001328)1.92165556
106Hand muscle atrophy (HP:0009130)1.89151679
107Annular pancreas (HP:0001734)1.88623017
108Impaired vibratory sensation (HP:0002495)1.88332264
109Renovascular hypertension (HP:0100817)1.87651297
110Mild short stature (HP:0003502)1.87011630
111Generalized myoclonic seizures (HP:0002123)1.86435828
112Coronal craniosynostosis (HP:0004440)1.84220855
113Hypoventilation (HP:0002791)1.83826425
114Incomplete penetrance (HP:0003829)1.83090807
115Postural tremor (HP:0002174)1.82735434
116Neuronal loss in central nervous system (HP:0002529)1.81064314
117Prolonged QT interval (HP:0001657)1.80514655
118Failure to thrive in infancy (HP:0001531)1.79719181
119Status epilepticus (HP:0002133)1.78879084
120Abnormal EKG (HP:0003115)1.76887376
121Ulnar bowing (HP:0003031)1.76564423
122Retinal dysplasia (HP:0007973)1.75667970
123Upper limb amyotrophy (HP:0009129)1.75521124
124Distal upper limb amyotrophy (HP:0007149)1.75521124
125Inability to walk (HP:0002540)1.75235087
126Gait ataxia (HP:0002066)1.74924774
127Neoplasm of the peripheral nervous system (HP:0100007)1.74795265
128Arnold-Chiari malformation (HP:0002308)1.74496059
129Degeneration of the lateral corticospinal tracts (HP:0002314)1.73673002
130Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.73673002
131Wide anterior fontanel (HP:0000260)1.73272913
132Mitral regurgitation (HP:0001653)1.73046530
133Aplasia/Hypoplasia of the brainstem (HP:0007362)1.72842405
134Hypoplasia of the brainstem (HP:0002365)1.72842405
135Congenital stationary night blindness (HP:0007642)1.71414785
136Lower limb amyotrophy (HP:0007210)1.70300947
137Hyperextensible skin (HP:0000974)1.69261387
138Abnormality of the diencephalon (HP:0010662)1.65268983
139Cortical dysplasia (HP:0002539)1.64377311
140Cutaneous finger syndactyly (HP:0010554)1.64040872
141Broad metatarsal (HP:0001783)1.60098616
142Morphological abnormality of the middle ear (HP:0008609)1.59969767
143Increased nuchal translucency (HP:0010880)1.56147092
144Tetraplegia (HP:0002445)1.55680376
145Heterotopia (HP:0002282)1.55439240
146Overgrowth (HP:0001548)1.55422497
147Split foot (HP:0001839)1.54996907
148Wormian bones (HP:0002645)1.53629955
149Alacrima (HP:0000522)1.51713531
150Trigonocephaly (HP:0000243)1.51297478
151Sleep apnea (HP:0010535)1.50988971
152Cutaneous syndactyly (HP:0012725)1.50940168

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.00953878
2NTRK33.95898255
3EPHA43.70419478
4MAP3K93.61090865
5MAP3K43.02747650
6MINK12.74394941
7PAK62.52731741
8MAP2K72.35975404
9DAPK22.28175222
10NTRK22.26730309
11NTRK12.07714762
12KSR21.93397967
13PDGFRA1.91824441
14PRKD31.91743800
15CAMKK11.89060646
16TNIK1.69458137
17CASK1.66485419
18KSR11.63289321
19MAP2K41.61554867
20PRPF4B1.60294629
21CDK51.58184324
22EPHB21.52441353
23MAPK131.48649043
24CAMKK21.48253186
25PHKG21.45242674
26PHKG11.45242674
27MAP3K121.44369975
28UHMK11.41986980
29PTK21.37139919
30ARAF1.28563596
31PLK21.28258899
32CDK191.27378532
33PNCK1.25655883
34GRK51.24472407
35STK381.19435617
36TYRO31.17731516
37PRKCG1.16793516
38FGFR21.14807909
39MAP3K21.13597746
40DAPK11.12327821
41MOS1.10644988
42SIK21.06483578
43SGK2231.04934160
44SGK4941.04934160
45CDK141.03860534
46CDK181.03765890
47TRIB31.03523618
48CDK151.03092877
49PAK31.02327314
50LATS20.98004718
51RIPK40.97912594
52MET0.97545044
53FES0.97131872
54CAMK2A0.92717151
55CSNK1G20.92251219
56TAOK10.90730411
57CDK11A0.90427392
58PRKCH0.87988495
59OXSR10.87024611
60RET0.86309325
61STK110.84309997
62DYRK1A0.81875765
63PAK20.81383239
64LMTK20.79732598
65CAMK10.77412728
66TESK10.75874547
67CAMK2B0.74444448
68LATS10.74245377
69WNK30.73857618
70MARK20.73747660
71SGK20.72752430
72WNK10.71539621
73ERBB40.71309954
74MAP3K130.71029381
75PKN20.69424927
76RIPK10.69047254
77PINK10.67565363
78ALK0.65831271
79CDK120.64086243
80ERBB30.64028172
81ROCK10.63110138
82NEK60.62237505
83SGK10.61125549
84NEK90.60988048
85EEF2K0.60913795
86SGK30.60703332
87CAMK1G0.60105238
88CSNK1A1L0.57791165
89CDC42BPA0.57415575
90PRKCZ0.57290477
91SCYL20.57219054
92BCR0.56805405
93CAMK2D0.56750677
94PRKCE0.55856790
95RAF10.54773049
96PDGFRB0.53759777
97DYRK20.53478594
98PKN10.52586045
99NEK10.52542577
100DDR20.51165513
101ROCK20.50689488
102FER0.49348550
103RPS6KA30.49245142
104FYN0.49000281
105LIMK10.48786428
106DMPK0.48285181
107MTOR0.48115976
108STK390.47520032
109CSNK1G30.47188667
110MAPK100.46757094
111FGFR10.45649667
112PDPK10.45239404
113CAMK2G0.44632840
114DYRK1B0.43780821
115MAP3K10.43674790
116RPS6KA20.43304779
117BMPR20.43126153
118CSNK1G10.42615514
119PDK10.42513654
120PTK2B0.41891420
121CSNK1E0.41133608
122BRSK10.40973295
123EPHA20.39899999
124TNK20.38884095
125ICK0.38867391
126MAP2K10.38733238
127CSNK1D0.35519878

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.54726744
2Synaptic vesicle cycle_Homo sapiens_hsa047213.42957497
3GABAergic synapse_Homo sapiens_hsa047272.89873692
4Olfactory transduction_Homo sapiens_hsa047402.80980715
5Circadian entrainment_Homo sapiens_hsa047132.67051923
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.63657174
7Morphine addiction_Homo sapiens_hsa050322.60578725
8Glutamatergic synapse_Homo sapiens_hsa047242.47208068
9Long-term potentiation_Homo sapiens_hsa047202.33596032
10Amphetamine addiction_Homo sapiens_hsa050312.27338502
11Dopaminergic synapse_Homo sapiens_hsa047282.21939989
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.20408850
13Insulin secretion_Homo sapiens_hsa049112.07795702
14Salivary secretion_Homo sapiens_hsa049702.01132863
15Cholinergic synapse_Homo sapiens_hsa047251.99615265
16Cocaine addiction_Homo sapiens_hsa050301.82180589
17Gastric acid secretion_Homo sapiens_hsa049711.74004071
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73525717
19Serotonergic synapse_Homo sapiens_hsa047261.72047557
20Long-term depression_Homo sapiens_hsa047301.71802470
21Taste transduction_Homo sapiens_hsa047421.70900197
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.69836018
23Renin secretion_Homo sapiens_hsa049241.67517130
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.63636759
25Oxytocin signaling pathway_Homo sapiens_hsa049211.58160404
26Gap junction_Homo sapiens_hsa045401.46048947
27Collecting duct acid secretion_Homo sapiens_hsa049661.45522738
28Hippo signaling pathway_Homo sapiens_hsa043901.44296960
29Calcium signaling pathway_Homo sapiens_hsa040201.38692827
30GnRH signaling pathway_Homo sapiens_hsa049121.33683877
31Axon guidance_Homo sapiens_hsa043601.29146807
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26680441
33Type II diabetes mellitus_Homo sapiens_hsa049301.24292528
34cAMP signaling pathway_Homo sapiens_hsa040241.22607539
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.20607639
36Adherens junction_Homo sapiens_hsa045201.19755577
37Vitamin B6 metabolism_Homo sapiens_hsa007501.17715806
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15450051
39Estrogen signaling pathway_Homo sapiens_hsa049151.15151911
40Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.14254000
41Phototransduction_Homo sapiens_hsa047441.11015722
42ECM-receptor interaction_Homo sapiens_hsa045121.05476372
43Glioma_Homo sapiens_hsa052141.05404350
44Vibrio cholerae infection_Homo sapiens_hsa051101.05214401
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05039386
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04998622
47Melanogenesis_Homo sapiens_hsa049161.02799380
48ErbB signaling pathway_Homo sapiens_hsa040121.02702200
49Focal adhesion_Homo sapiens_hsa045101.02109544
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01585941
51Basal cell carcinoma_Homo sapiens_hsa052171.01175895
52Central carbon metabolism in cancer_Homo sapiens_hsa052301.00274064
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97835565
54Cardiac muscle contraction_Homo sapiens_hsa042600.95776523
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.92338417
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.84802176
57Oocyte meiosis_Homo sapiens_hsa041140.84426339
58Proteoglycans in cancer_Homo sapiens_hsa052050.83739123
59Phospholipase D signaling pathway_Homo sapiens_hsa040720.83703187
60Dorso-ventral axis formation_Homo sapiens_hsa043200.81028016
61Pancreatic secretion_Homo sapiens_hsa049720.79601082
62Dilated cardiomyopathy_Homo sapiens_hsa054140.78790627
63Thyroid hormone synthesis_Homo sapiens_hsa049180.75980049
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.75672518
65MicroRNAs in cancer_Homo sapiens_hsa052060.73092240
66Alcoholism_Homo sapiens_hsa050340.73014164
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72186842
68AMPK signaling pathway_Homo sapiens_hsa041520.70004824
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.69285449
70MAPK signaling pathway_Homo sapiens_hsa040100.68439670
71Chronic myeloid leukemia_Homo sapiens_hsa052200.68329360
72Choline metabolism in cancer_Homo sapiens_hsa052310.65465901
73AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64657153
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64467701
75Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64210042
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.63204820
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62995481
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61770352
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61638576
80Endometrial cancer_Homo sapiens_hsa052130.61316015
81Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.60732699
82Melanoma_Homo sapiens_hsa052180.60476785
83Ras signaling pathway_Homo sapiens_hsa040140.60027583
84Renal cell carcinoma_Homo sapiens_hsa052110.59543971
85Protein digestion and absorption_Homo sapiens_hsa049740.58987068
86Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58767068
87Notch signaling pathway_Homo sapiens_hsa043300.58624903
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58412539
89Circadian rhythm_Homo sapiens_hsa047100.56924830
90Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56185161
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54680906
92Type I diabetes mellitus_Homo sapiens_hsa049400.53892877
93Endocytosis_Homo sapiens_hsa041440.53834536
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.52808641
95mTOR signaling pathway_Homo sapiens_hsa041500.51834616
96Rap1 signaling pathway_Homo sapiens_hsa040150.51219851
97Nitrogen metabolism_Homo sapiens_hsa009100.50737544
98Thyroid cancer_Homo sapiens_hsa052160.50418036
99Glucagon signaling pathway_Homo sapiens_hsa049220.49281047
100VEGF signaling pathway_Homo sapiens_hsa043700.48059817
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47824550
102Wnt signaling pathway_Homo sapiens_hsa043100.47203372
103Inositol phosphate metabolism_Homo sapiens_hsa005620.46468163
104Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44984118
105Prion diseases_Homo sapiens_hsa050200.44101004
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43387311
107Insulin signaling pathway_Homo sapiens_hsa049100.42838607
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42234221
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42201251
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41534948
111Ovarian steroidogenesis_Homo sapiens_hsa049130.40504832
112Non-small cell lung cancer_Homo sapiens_hsa052230.40477609
113Bile secretion_Homo sapiens_hsa049760.39002864
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37446922
115Colorectal cancer_Homo sapiens_hsa052100.37397817
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37384550
117Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.36369092
118Chemokine signaling pathway_Homo sapiens_hsa040620.34362165
119Hedgehog signaling pathway_Homo sapiens_hsa043400.33521810
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31662663
121Tight junction_Homo sapiens_hsa045300.31265838
122Alzheimers disease_Homo sapiens_hsa050100.29650740

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