Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 5.92727884 |
2 | Golgi transport vesicle coating (GO:0048200) | 5.92727884 |
3 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.42071621 |
4 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 4.22103445 |
5 | protein retention in ER lumen (GO:0006621) | 4.14724505 |
6 | plasma membrane repair (GO:0001778) | 4.11847481 |
7 | apoptotic cell clearance (GO:0043277) | 4.01352866 |
8 | positive regulation of nuclease activity (GO:0032075) | 3.98295641 |
9 | 4-hydroxyproline metabolic process (GO:0019471) | 3.87206775 |
10 | proline biosynthetic process (GO:0006561) | 3.74833741 |
11 | negative regulation of cell size (GO:0045792) | 3.69550376 |
12 | * retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.68566836 |
13 | low-density lipoprotein particle clearance (GO:0034383) | 3.65450130 |
14 | endoplasmic reticulum unfolded protein response (GO:0030968) | 3.61250182 |
15 | regulation of nuclease activity (GO:0032069) | 3.60300618 |
16 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.52891817 |
17 | lysine metabolic process (GO:0006553) | 3.50505759 |
18 | lysine catabolic process (GO:0006554) | 3.50505759 |
19 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.49534545 |
20 | tricarboxylic acid metabolic process (GO:0072350) | 3.48662216 |
21 | regulation of cholesterol homeostasis (GO:2000188) | 3.45619221 |
22 | cellular response to unfolded protein (GO:0034620) | 3.43525078 |
23 | regulation of fatty acid beta-oxidation (GO:0031998) | 3.39212531 |
24 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.34698433 |
25 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.31219962 |
26 | macroautophagy (GO:0016236) | 3.29971340 |
27 | ER-nucleus signaling pathway (GO:0006984) | 3.29675329 |
28 | 2-oxoglutarate metabolic process (GO:0006103) | 3.27770765 |
29 | barbed-end actin filament capping (GO:0051016) | 3.27390699 |
30 | modulation by symbiont of host cellular process (GO:0044068) | 3.26439260 |
31 | peptidyl-proline hydroxylation (GO:0019511) | 3.22155440 |
32 | protein hydroxylation (GO:0018126) | 3.22058837 |
33 | maternal placenta development (GO:0001893) | 3.21038088 |
34 | cellular response to topologically incorrect protein (GO:0035967) | 3.20875931 |
35 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.18068298 |
36 | negative regulation of fatty acid transport (GO:2000192) | 3.15008513 |
37 | sarcomere organization (GO:0045214) | 3.06427118 |
38 | regulation of cholesterol storage (GO:0010885) | 3.05485652 |
39 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.05375213 |
40 | pinocytosis (GO:0006907) | 3.02247840 |
41 | stress fiber assembly (GO:0043149) | 3.01166190 |
42 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.01161437 |
43 | regulation of fatty acid oxidation (GO:0046320) | 3.00331368 |
44 | COPII vesicle coating (GO:0048208) | 2.99349511 |
45 | modulation by virus of host process (GO:0019054) | 2.97819024 |
46 | activation of Rac GTPase activity (GO:0032863) | 2.97404344 |
47 | apoptotic process involved in morphogenesis (GO:0060561) | 2.95283514 |
48 | basement membrane organization (GO:0071711) | 2.93144925 |
49 | epithelial cell-cell adhesion (GO:0090136) | 2.92436196 |
50 | modulation by virus of host morphology or physiology (GO:0019048) | 2.88551675 |
51 | positive regulation of p38MAPK cascade (GO:1900745) | 2.88361794 |
52 | positive regulation of histone deacetylation (GO:0031065) | 2.86683703 |
53 | vesicle coating (GO:0006901) | 2.85328494 |
54 | proline metabolic process (GO:0006560) | 2.84685657 |
55 | oxaloacetate metabolic process (GO:0006107) | 2.84390083 |
56 | protein heterotrimerization (GO:0070208) | 2.84365784 |
57 | valine metabolic process (GO:0006573) | 2.81602000 |
58 | skin morphogenesis (GO:0043589) | 2.79837859 |
59 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.79502180 |
60 | response to laminar fluid shear stress (GO:0034616) | 2.78799215 |
61 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.77076536 |
62 | response to endoplasmic reticulum stress (GO:0034976) | 2.76806092 |
63 | carnitine shuttle (GO:0006853) | 2.76189170 |
64 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.74528569 |
65 | cellular response to nutrient (GO:0031670) | 2.73878556 |
66 | mannose metabolic process (GO:0006013) | 2.73027928 |
67 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.72713696 |
68 | fatty acid transmembrane transport (GO:1902001) | 2.71158488 |
69 | semaphorin-plexin signaling pathway (GO:0071526) | 2.71152138 |
70 | regulation of p38MAPK cascade (GO:1900744) | 2.69853233 |
71 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.69746434 |
72 | positive regulation of fatty acid oxidation (GO:0046321) | 2.69690631 |
73 | response to unfolded protein (GO:0006986) | 2.68404462 |
74 | NADH metabolic process (GO:0006734) | 2.67342795 |
75 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.64668920 |
76 | aspartate family amino acid catabolic process (GO:0009068) | 2.63444082 |
77 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.62336246 |
78 | glucose 6-phosphate metabolic process (GO:0051156) | 2.60851605 |
79 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.60453071 |
80 | adherens junction assembly (GO:0034333) | 2.60350048 |
81 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.60156868 |
82 | alpha-linolenic acid metabolic process (GO:0036109) | 2.59500862 |
83 | regulation of extracellular matrix disassembly (GO:0010715) | 2.59119766 |
84 | fatty acid beta-oxidation (GO:0006635) | 2.59085494 |
85 | positive regulation of protein dephosphorylation (GO:0035307) | 2.58754039 |
86 | cell-substrate junction assembly (GO:0007044) | 2.58581654 |
87 | cardiac myofibril assembly (GO:0055003) | 2.57975901 |
88 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.56560753 |
89 | embryo implantation (GO:0007566) | 2.56158296 |
90 | glucose catabolic process (GO:0006007) | 2.55660933 |
91 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.55413392 |
92 | response to topologically incorrect protein (GO:0035966) | 2.55195586 |
93 | endodermal cell differentiation (GO:0035987) | 2.54907322 |
94 | protein targeting to plasma membrane (GO:0072661) | 2.54244648 |
95 | GDP-mannose metabolic process (GO:0019673) | 2.53827777 |
96 | negative regulation of viral release from host cell (GO:1902187) | 2.53092061 |
97 | positive regulation of receptor recycling (GO:0001921) | 2.52986082 |
98 | tricarboxylic acid cycle (GO:0006099) | 2.52273284 |
99 | negative regulation of necroptotic process (GO:0060546) | 2.51406329 |
100 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.49313349 |
101 | cell adhesion mediated by integrin (GO:0033627) | 2.48747649 |
102 | adhesion of symbiont to host (GO:0044406) | 2.47505315 |
103 | activation of MAPKKK activity (GO:0000185) | 2.45662406 |
104 | pentose-phosphate shunt (GO:0006098) | 2.45266200 |
105 | endothelial cell chemotaxis (GO:0035767) | 2.44579344 |
106 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.43692561 |
107 | cellular response to vitamin (GO:0071295) | 2.42627776 |
108 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.41956405 |
109 | amyloid precursor protein catabolic process (GO:0042987) | 2.41777003 |
110 | polarized epithelial cell differentiation (GO:0030859) | 2.41766010 |
111 | regulation of early endosome to late endosome transport (GO:2000641) | 2.41648614 |
112 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.40741311 |
113 | cell-cell junction maintenance (GO:0045217) | 2.40283862 |
114 | regulation of tight junction assembly (GO:2000810) | 2.40101203 |
115 | embryonic process involved in female pregnancy (GO:0060136) | 2.39963316 |
116 | focal adhesion assembly (GO:0048041) | 2.38421172 |
117 | cell-substrate adherens junction assembly (GO:0007045) | 2.38421172 |
118 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.37977615 |
119 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.37645060 |
120 | collagen fibril organization (GO:0030199) | 2.36773153 |
121 | actin-myosin filament sliding (GO:0033275) | 2.36429380 |
122 | muscle filament sliding (GO:0030049) | 2.36429380 |
123 | negative regulation of lipid transport (GO:0032369) | 2.36101963 |
124 | fatty acid oxidation (GO:0019395) | 2.35163124 |
125 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.34662287 |
126 | negative regulation of fibrinolysis (GO:0051918) | 2.33885371 |
127 | sulfur amino acid catabolic process (GO:0000098) | 2.33571705 |
128 | UV protection (GO:0009650) | 2.33360135 |
129 | positive regulation of extracellular matrix organization (GO:1903055) | 2.32635686 |
130 | protein localization to endosome (GO:0036010) | 2.31941592 |
131 | fatty acid homeostasis (GO:0055089) | 2.31742171 |
132 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.31130223 |
133 | protein maturation by protein folding (GO:0022417) | 2.31029937 |
134 | blood vessel endothelial cell migration (GO:0043534) | 2.31019111 |
135 | response to mercury ion (GO:0046689) | 2.30420774 |
136 | regulation of defense response to virus by virus (GO:0050690) | 2.29015525 |
137 | lipid oxidation (GO:0034440) | 2.28551060 |
138 | retrograde transport, endosome to Golgi (GO:0042147) | 2.28164234 |
139 | growth hormone receptor signaling pathway (GO:0060396) | 2.27997647 |
140 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.27925494 |
141 | hyaluronan catabolic process (GO:0030214) | 2.27749257 |
142 | actin filament bundle organization (GO:0061572) | 2.27375559 |
143 | actin filament bundle assembly (GO:0051017) | 2.27375559 |
144 | negative regulation of skeletal muscle tissue development (GO:0048642) | 2.27218506 |
145 | positive regulation of triglyceride metabolic process (GO:0090208) | 2.27111906 |
146 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.26736801 |
147 | protein carboxylation (GO:0018214) | 2.26736801 |
148 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.26347906 |
149 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.24528514 |
150 | regulation of cholesterol metabolic process (GO:0090181) | 2.23816298 |
151 | regulation of ARF protein signal transduction (GO:0032012) | 2.23758471 |
152 | regulation of necrotic cell death (GO:0010939) | 2.23552261 |
153 | regulation of superoxide anion generation (GO:0032928) | 2.22999602 |
154 | cortical actin cytoskeleton organization (GO:0030866) | 2.21031149 |
155 | positive regulation of myotube differentiation (GO:0010831) | 2.20405434 |
156 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.19980804 |
157 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.19615928 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.19615133 |
2 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.79243716 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.55914673 |
4 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.89585554 |
5 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.87954065 |
6 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.83049319 |
7 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.75395764 |
8 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.61862265 |
9 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.34797946 |
10 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.21116276 |
11 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.19973407 |
12 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.18846013 |
13 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.15790229 |
14 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.12066710 |
15 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.06582762 |
16 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.01665026 |
17 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.96067101 |
18 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.94398166 |
19 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.89889211 |
20 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.83088348 |
21 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.80711288 |
22 | * MYC_22102868_ChIP-Seq_BL_Human | 1.77282757 |
23 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.76262049 |
24 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.73087820 |
25 | ATF3_27146783_Chip-Seq_COLON_Human | 1.72486329 |
26 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.67109624 |
27 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.66668995 |
28 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.66636328 |
29 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.65654898 |
30 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.61906853 |
31 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.60307925 |
32 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.57026119 |
33 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.56946682 |
34 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.56946682 |
35 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.55909612 |
36 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.55211760 |
37 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.52604588 |
38 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.52276045 |
39 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.49076327 |
40 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.48485127 |
41 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.47824864 |
42 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.43154185 |
43 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.40478396 |
44 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.39946250 |
45 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.39058441 |
46 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.38076383 |
47 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.37689116 |
48 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.36454009 |
49 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.35846729 |
50 | * HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.35039842 |
51 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.34693089 |
52 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.34590582 |
53 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.31977357 |
54 | P68_20966046_ChIP-Seq_HELA_Human | 1.31597043 |
55 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.29534471 |
56 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.26802012 |
57 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.26637364 |
58 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.25270387 |
59 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.25221901 |
60 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.25104112 |
61 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.24251666 |
62 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.23904515 |
63 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.22892985 |
64 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.22461950 |
65 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.21837548 |
66 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.21441400 |
67 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.21199378 |
68 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.20127890 |
69 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.19794855 |
70 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.18039253 |
71 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.17337737 |
72 | MAF_26560356_Chip-Seq_TH2_Human | 1.16924416 |
73 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.15661709 |
74 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.15466499 |
75 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.15397674 |
76 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.15037233 |
77 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.14806435 |
78 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.13120515 |
79 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.13056068 |
80 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12800789 |
81 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12617572 |
82 | * SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.11973893 |
83 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.11822398 |
84 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.11564590 |
85 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.11201908 |
86 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.11134884 |
87 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.11007890 |
88 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.10541556 |
89 | GATA1_19941826_ChIP-Seq_K562_Human | 1.10142093 |
90 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.10108531 |
91 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.09782392 |
92 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.09575391 |
93 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.09278184 |
94 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.08820564 |
95 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08164458 |
96 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.07665120 |
97 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07417668 |
98 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.06499018 |
99 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.06426592 |
100 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.05776944 |
101 | MAF_26560356_Chip-Seq_TH1_Human | 1.05269604 |
102 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.05169818 |
103 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.04969234 |
104 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.04908176 |
105 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.04863944 |
106 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.03458280 |
107 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.03261329 |
108 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.02928268 |
109 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.01657168 |
110 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01566869 |
111 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.01314000 |
112 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.00970487 |
113 | SPI1_23127762_ChIP-Seq_K562_Human | 1.00357180 |
114 | UTX_26944678_Chip-Seq_JUKART_Human | 0.99875541 |
115 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.99620471 |
116 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.99507088 |
117 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.99455718 |
118 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.99112331 |
119 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.98944308 |
120 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.98896327 |
121 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.98759784 |
122 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.98358496 |
123 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.98277424 |
124 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.98261583 |
125 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.98065020 |
126 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.96594849 |
127 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.95872723 |
128 | * TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.93210467 |
129 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.92807591 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.25135200 |
2 | MP0008438_abnormal_cutaneous_collagen | 3.87230878 |
3 | MP0005451_abnormal_body_composition | 3.71401073 |
4 | MP0002837_dystrophic_cardiac_calcinosis | 3.01593139 |
5 | MP0008260_abnormal_autophagy | 2.34890365 |
6 | MP0000751_myopathy | 2.32293196 |
7 | MP0000013_abnormal_adipose_tissue | 2.30800055 |
8 | MP0005670_abnormal_white_adipose | 2.29946068 |
9 | MP0009840_abnormal_foam_cell | 2.16572294 |
10 | MP0003566_abnormal_cell_adhesion | 2.12938299 |
11 | MP0005275_abnormal_skin_tensile | 2.09492850 |
12 | MP0004084_abnormal_cardiac_muscle | 2.04363718 |
13 | MP0004272_abnormal_basement_membrane | 1.93677876 |
14 | MP0002877_abnormal_melanocyte_morpholog | 1.93633221 |
15 | MP0005083_abnormal_biliary_tract | 1.89779242 |
16 | MP0003436_decreased_susceptibility_to | 1.89625777 |
17 | MP0005666_abnormal_adipose_tissue | 1.89267351 |
18 | MP0003283_abnormal_digestive_organ | 1.87444674 |
19 | MP0005058_abnormal_lysosome_morphology | 1.85717665 |
20 | MP0000749_muscle_degeneration | 1.84401167 |
21 | MP0003300_gastrointestinal_ulcer | 1.83878605 |
22 | MP0002139_abnormal_hepatobiliary_system | 1.81987543 |
23 | MP0003279_aneurysm | 1.79811341 |
24 | MP0010352_gastrointestinal_tract_polyps | 1.79493094 |
25 | MP0004130_abnormal_muscle_cell | 1.76260899 |
26 | MP0004185_abnormal_adipocyte_glucose | 1.75579088 |
27 | MP0001958_emphysema | 1.74442973 |
28 | MP0003329_amyloid_beta_deposits | 1.74022155 |
29 | MP0005375_adipose_tissue_phenotype | 1.72647652 |
30 | * MP0004087_abnormal_muscle_fiber | 1.66821908 |
31 | MP0003191_abnormal_cellular_cholesterol | 1.65188974 |
32 | MP0003195_calcinosis | 1.63481102 |
33 | MP0000678_abnormal_parathyroid_gland | 1.62683521 |
34 | MP0005360_urolithiasis | 1.62391887 |
35 | * MP0002269_muscular_atrophy | 1.61671213 |
36 | * MP0004858_abnormal_nervous_system | 1.61033526 |
37 | MP0000003_abnormal_adipose_tissue | 1.58384569 |
38 | MP0000747_muscle_weakness | 1.57721621 |
39 | MP0005365_abnormal_bile_salt | 1.57086815 |
40 | MP0005330_cardiomyopathy | 1.55732846 |
41 | MP0003453_abnormal_keratinocyte_physiol | 1.54306095 |
42 | MP0000858_altered_metastatic_potential | 1.52641184 |
43 | MP0004036_abnormal_muscle_relaxation | 1.51356330 |
44 | MP0003172_abnormal_lysosome_physiology | 1.50325035 |
45 | MP0009278_abnormal_bone_marrow | 1.48647058 |
46 | MP0002909_abnormal_adrenal_gland | 1.47816734 |
47 | MP0003252_abnormal_bile_duct | 1.46210736 |
48 | MP0008961_abnormal_basal_metabolism | 1.45678905 |
49 | MP0005076_abnormal_cell_differentiation | 1.42831294 |
50 | MP0005257_abnormal_intraocular_pressure | 1.41971225 |
51 | MP0002896_abnormal_bone_mineralization | 1.38268996 |
52 | MP0005623_abnormal_meninges_morphology | 1.37859392 |
53 | * MP0000750_abnormal_muscle_regeneration | 1.37299531 |
54 | MP0010329_abnormal_lipoprotein_level | 1.33165155 |
55 | MP0005023_abnormal_wound_healing | 1.31399775 |
56 | * MP0000759_abnormal_skeletal_muscle | 1.28989095 |
57 | MP0004947_skin_inflammation | 1.28716914 |
58 | MP0002796_impaired_skin_barrier | 1.26365367 |
59 | MP0001849_ear_inflammation | 1.24870443 |
60 | MP0005167_abnormal_blood-brain_barrier | 1.23030083 |
61 | MP0008775_abnormal_heart_ventricle | 1.22593555 |
62 | MP0003045_fibrosis | 1.21410367 |
63 | MP0006054_spinal_hemorrhage | 1.21020570 |
64 | MP0010630_abnormal_cardiac_muscle | 1.18669815 |
65 | MP0000733_abnormal_muscle_development | 1.18470693 |
66 | MP0009643_abnormal_urine_homeostasis | 1.17198557 |
67 | MP0005501_abnormal_skin_physiology | 1.17012359 |
68 | MP0003075_altered_response_to | 1.16509908 |
69 | MP0003646_muscle_fatigue | 1.15631809 |
70 | MP0002168_other_aberrant_phenotype | 1.15018092 |
71 | MP0000604_amyloidosis | 1.14352827 |
72 | MP0001348_abnormal_lacrimal_gland | 1.11504861 |
73 | MP0010368_abnormal_lymphatic_system | 1.10657806 |
74 | MP0005332_abnormal_amino_acid | 1.09619567 |
75 | MP0001756_abnormal_urination | 1.09450181 |
76 | MP0002249_abnormal_larynx_morphology | 1.07719868 |
77 | MP0005319_abnormal_enzyme/_coenzyme | 1.07490356 |
78 | MP0003091_abnormal_cell_migration | 1.07455201 |
79 | MP0009384_cardiac_valve_regurgitation | 1.07338149 |
80 | MP0002138_abnormal_hepatobiliary_system | 1.07329567 |
81 | MP0003879_abnormal_hair_cell | 1.07070704 |
82 | MP0001915_intracranial_hemorrhage | 1.06893933 |
83 | MP0000609_abnormal_liver_physiology | 1.06399541 |
84 | MP0004043_abnormal_pH_regulation | 1.05970783 |
85 | MP0001666_abnormal_nutrient_absorption | 1.05453841 |
86 | MP0002118_abnormal_lipid_homeostasis | 1.04633142 |
87 | MP0001544_abnormal_cardiovascular_syste | 1.04206509 |
88 | MP0005385_cardiovascular_system_phenoty | 1.04206509 |
89 | MP0005409_darkened_coat_color | 1.03542382 |
90 | MP0004233_abnormal_muscle_weight | 1.01686037 |
91 | MP0005503_abnormal_tendon_morphology | 1.00854950 |
92 | MP0009333_abnormal_splenocyte_physiolog | 1.00623482 |
93 | MP0000537_abnormal_urethra_morphology | 1.00232833 |
94 | MP0005620_abnormal_muscle_contractility | 1.00025867 |
95 | MP0009780_abnormal_chondrocyte_physiolo | 0.99359638 |
96 | MP0005085_abnormal_gallbladder_physiolo | 0.98731595 |
97 | MP0005220_abnormal_exocrine_pancreas | 0.97080128 |
98 | MP0002078_abnormal_glucose_homeostasis | 0.96783415 |
99 | MP0002972_abnormal_cardiac_muscle | 0.96266900 |
100 | MP0003303_peritoneal_inflammation | 0.96252478 |
101 | MP0004510_myositis | 0.95920885 |
102 | * MP0002106_abnormal_muscle_physiology | 0.94121490 |
103 | MP0003123_paternal_imprinting | 0.93358650 |
104 | MP0003221_abnormal_cardiomyocyte_apopto | 0.93052721 |
105 | MP0000767_abnormal_smooth_muscle | 0.92905578 |
106 | MP0001533_abnormal_skeleton_physiology | 0.92767720 |
107 | MP0005621_abnormal_cell_physiology | 0.92382165 |
108 | MP0010234_abnormal_vibrissa_follicle | 0.91572141 |
109 | MP0000681_abnormal_thyroid_gland | 0.90509228 |
110 | MP0006138_congestive_heart_failure | 0.89671194 |
111 | MP0004215_abnormal_myocardial_fiber | 0.89225834 |
112 | MP0002060_abnormal_skin_morphology | 0.89021359 |
113 | MP0004264_abnormal_extraembryonic_tissu | 0.86562393 |
114 | MP0001944_abnormal_pancreas_morphology | 0.82359304 |
115 | MP0000343_altered_response_to | 0.80843796 |
116 | MP0002998_abnormal_bone_remodeling | 0.80547982 |
117 | * MP0005369_muscle_phenotype | 0.80327145 |
118 | MP0008875_abnormal_xenobiotic_pharmacok | 0.79893875 |
119 | MP0005464_abnormal_platelet_physiology | 0.79331472 |
120 | MP0002089_abnormal_postnatal_growth/wei | 0.78715293 |
121 | MP0002971_abnormal_brown_adipose | 0.78631824 |
122 | MP0002295_abnormal_pulmonary_circulatio | 0.78291209 |
123 | MP0003634_abnormal_glial_cell | 0.77917438 |
124 | MP0001542_abnormal_bone_strength | 0.77711921 |
125 | MP0001661_extended_life_span | 0.76934356 |
126 | MP0001730_embryonic_growth_arrest | 0.76339825 |
127 | MP0010030_abnormal_orbit_morphology | 0.76089560 |
128 | MP0005390_skeleton_phenotype | 0.76020313 |
129 | MP0009931_abnormal_skin_appearance | 0.75820569 |
130 | MP0000534_abnormal_ureter_morphology | 0.75438912 |
131 | MP0001243_abnormal_dermal_layer | 0.75095097 |
132 | MP0005508_abnormal_skeleton_morphology | 0.74306583 |
133 | MP0008874_decreased_physiological_sensi | 0.74127034 |
134 | MP0001545_abnormal_hematopoietic_system | 0.73851853 |
135 | MP0005397_hematopoietic_system_phenotyp | 0.73851853 |
136 | MP0001879_abnormal_lymphatic_vessel | 0.72831267 |
137 | MP0000598_abnormal_liver_morphology | 0.72110686 |
138 | MP0003828_pulmonary_edema | 0.70738270 |
139 | MP0004808_abnormal_hematopoietic_stem | 0.70505527 |
140 | MP0003183_abnormal_peptide_metabolism | 0.69739357 |
141 | MP0000266_abnormal_heart_morphology | 0.69159576 |
142 | MP0002128_abnormal_blood_circulation | 0.69020871 |
143 | MP0002970_abnormal_white_adipose | 0.67935504 |
144 | MP0002332_abnormal_exercise_endurance | 0.67806416 |
145 | MP0009672_abnormal_birth_weight | 0.65886987 |
146 | MP0003795_abnormal_bone_structure | 0.64883541 |
147 | MP0003942_abnormal_urinary_system | 0.64381569 |
148 | MP0001216_abnormal_epidermal_layer | 0.62075834 |
149 | MP0003448_altered_tumor_morphology | 0.61254806 |
150 | MP0001873_stomach_inflammation | 0.60773741 |
151 | MP0002113_abnormal_skeleton_development | 0.60534334 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 4.45501749 |
2 | Premature rupture of membranes (HP:0001788) | 3.96378134 |
3 | Cerebral aneurysm (HP:0004944) | 3.81668735 |
4 | Increased connective tissue (HP:0009025) | 3.50029908 |
5 | Hyperacusis (HP:0010780) | 3.27923088 |
6 | Asymmetric septal hypertrophy (HP:0001670) | 3.16548357 |
7 | Type 1 muscle fiber predominance (HP:0003803) | 3.04726412 |
8 | Myoglobinuria (HP:0002913) | 3.00532604 |
9 | Shallow orbits (HP:0000586) | 2.90606202 |
10 | Long toe (HP:0010511) | 2.89163923 |
11 | Hypoglycemic coma (HP:0001325) | 2.88163564 |
12 | Broad metatarsal (HP:0001783) | 2.88148931 |
13 | Ankle contracture (HP:0006466) | 2.82368938 |
14 | Difficulty climbing stairs (HP:0003551) | 2.77605481 |
15 | Distal lower limb amyotrophy (HP:0008944) | 2.76619467 |
16 | Exercise-induced muscle cramps (HP:0003710) | 2.70669196 |
17 | Distal lower limb muscle weakness (HP:0009053) | 2.70268801 |
18 | Upper limb amyotrophy (HP:0009129) | 2.67856435 |
19 | Distal upper limb amyotrophy (HP:0007149) | 2.67856435 |
20 | Muscle fiber splitting (HP:0003555) | 2.66555707 |
21 | Flat acetabular roof (HP:0003180) | 2.65180233 |
22 | Hyporeflexia of lower limbs (HP:0002600) | 2.63412966 |
23 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.62180321 |
24 | Ketoacidosis (HP:0001993) | 2.61829850 |
25 | Aneurysm (HP:0002617) | 2.60657206 |
26 | Exercise-induced myalgia (HP:0003738) | 2.54934095 |
27 | Cervical subluxation (HP:0003308) | 2.52915645 |
28 | Hand muscle atrophy (HP:0009130) | 2.52528549 |
29 | Increased variability in muscle fiber diameter (HP:0003557) | 2.50203900 |
30 | Peritonitis (HP:0002586) | 2.46379793 |
31 | Sudden death (HP:0001699) | 2.45829075 |
32 | Difficulty running (HP:0009046) | 2.44304212 |
33 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.44111780 |
34 | Lymphangioma (HP:0100764) | 2.37579002 |
35 | Right ventricular cardiomyopathy (HP:0011663) | 2.36028343 |
36 | Myopathic facies (HP:0002058) | 2.35759594 |
37 | Mitral valve prolapse (HP:0001634) | 2.35454595 |
38 | Deep venous thrombosis (HP:0002625) | 2.31730032 |
39 | Vertebral compression fractures (HP:0002953) | 2.31342788 |
40 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.29436616 |
41 | Mucopolysacchariduria (HP:0008155) | 2.29436616 |
42 | Dysostosis multiplex (HP:0000943) | 2.27076997 |
43 | Disproportionate tall stature (HP:0001519) | 2.26753620 |
44 | Bladder diverticulum (HP:0000015) | 2.26626044 |
45 | Ketosis (HP:0001946) | 2.26018097 |
46 | Abnormality of the Achilles tendon (HP:0005109) | 2.25326586 |
47 | Achilles tendon contracture (HP:0001771) | 2.25112305 |
48 | Aortic dissection (HP:0002647) | 2.24354962 |
49 | Broad face (HP:0000283) | 2.24063438 |
50 | Axonal loss (HP:0003447) | 2.23754722 |
51 | Polycythemia (HP:0001901) | 2.23727950 |
52 | Atrophic scars (HP:0001075) | 2.23639903 |
53 | Insomnia (HP:0100785) | 2.23153844 |
54 | Gout (HP:0001997) | 2.22771016 |
55 | Mitral regurgitation (HP:0001653) | 2.22568527 |
56 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.21026809 |
57 | Aortic aneurysm (HP:0004942) | 2.20896410 |
58 | Xanthomatosis (HP:0000991) | 2.20643236 |
59 | Dilatation of the ascending aorta (HP:0005111) | 2.19477612 |
60 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.16062827 |
61 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.15197482 |
62 | Short nail (HP:0001799) | 2.13883401 |
63 | Ventricular tachycardia (HP:0004756) | 2.13589736 |
64 | Thin bony cortex (HP:0002753) | 2.13025275 |
65 | Turricephaly (HP:0000262) | 2.12822303 |
66 | Late onset (HP:0003584) | 2.12806649 |
67 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.12602870 |
68 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.12602870 |
69 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.12602870 |
70 | Scapular winging (HP:0003691) | 2.12031863 |
71 | Hyperglycemia (HP:0003074) | 2.11445189 |
72 | Spinal rigidity (HP:0003306) | 2.08409416 |
73 | Long palpebral fissure (HP:0000637) | 2.08191378 |
74 | Elbow flexion contracture (HP:0002987) | 2.08026699 |
75 | Stridor (HP:0010307) | 2.04489443 |
76 | Cerebral inclusion bodies (HP:0100314) | 2.03373980 |
77 | Back pain (HP:0003418) | 1.99727709 |
78 | Blue sclerae (HP:0000592) | 1.99685717 |
79 | Rhabdomyolysis (HP:0003201) | 1.97000536 |
80 | Obstructive sleep apnea (HP:0002870) | 1.96964310 |
81 | Fragile skin (HP:0001030) | 1.95472322 |
82 | Abnormality of carpal bone ossification (HP:0006257) | 1.93591357 |
83 | Skin nodule (HP:0200036) | 1.92878408 |
84 | Hemorrhage of the eye (HP:0011885) | 1.92016246 |
85 | Cholecystitis (HP:0001082) | 1.92004785 |
86 | Abnormal gallbladder physiology (HP:0012438) | 1.92004785 |
87 | Trismus (HP:0000211) | 1.91200562 |
88 | Genu recurvatum (HP:0002816) | 1.90516907 |
89 | Bundle branch block (HP:0011710) | 1.90046257 |
90 | Lower limb amyotrophy (HP:0007210) | 1.89371185 |
91 | Enlarged penis (HP:0000040) | 1.89356895 |
92 | Myocardial infarction (HP:0001658) | 1.88942648 |
93 | EMG: myopathic abnormalities (HP:0003458) | 1.87249874 |
94 | Hyperparathyroidism (HP:0000843) | 1.86550448 |
95 | Lipoatrophy (HP:0100578) | 1.85237578 |
96 | Abnormality of the acetabulum (HP:0003170) | 1.84689656 |
97 | Premature skin wrinkling (HP:0100678) | 1.84374514 |
98 | Soft skin (HP:0000977) | 1.84339517 |
99 | Abnormal ossification of hand bones (HP:0005921) | 1.83425124 |
100 | Abnormal cartilage morphology (HP:0002763) | 1.80533064 |
101 | Hypoalphalipoproteinemia (HP:0003233) | 1.80393000 |
102 | Metaphyseal cupping (HP:0003021) | 1.79402121 |
103 | J-shaped sella turcica (HP:0002680) | 1.79396852 |
104 | Abnormality of glycolipid metabolism (HP:0010969) | 1.78990039 |
105 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.78990039 |
106 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.78990039 |
107 | Ragged-red muscle fibers (HP:0003200) | 1.78347894 |
108 | Upper motor neuron abnormality (HP:0002127) | 1.78194040 |
109 | Ulnar deviation of the wrist (HP:0003049) | 1.77847306 |
110 | Limb-girdle muscle atrophy (HP:0003797) | 1.77186180 |
111 | Vascular tortuosity (HP:0004948) | 1.76700310 |
112 | Coxa vara (HP:0002812) | 1.76475961 |
113 | Abnormality of the thoracic spine (HP:0100711) | 1.75583989 |
114 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.74951310 |
115 | Osteolytic defects of the hand bones (HP:0009699) | 1.74951310 |
116 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.74567444 |
117 | Subaortic stenosis (HP:0001682) | 1.74567444 |
118 | Growth hormone excess (HP:0000845) | 1.74210644 |
119 | Frequent falls (HP:0002359) | 1.74022546 |
120 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.73881417 |
121 | Asymmetry of the thorax (HP:0001555) | 1.72501798 |
122 | Striae distensae (HP:0001065) | 1.72363271 |
123 | Global brain atrophy (HP:0002283) | 1.70924327 |
124 | Bulbar palsy (HP:0001283) | 1.70184636 |
125 | Reticulocytosis (HP:0001923) | 1.69920442 |
126 | Hypercortisolism (HP:0001578) | 1.68358162 |
127 | Ulnar bowing (HP:0003031) | 1.68155701 |
128 | Cellulitis (HP:0100658) | 1.68126429 |
129 | Ovoid vertebral bodies (HP:0003300) | 1.67902174 |
130 | Slender build (HP:0001533) | 1.67737992 |
131 | Abnormality of dentin (HP:0010299) | 1.67684836 |
132 | Joint laxity (HP:0001388) | 1.67651151 |
133 | Generalized amyotrophy (HP:0003700) | 1.67269482 |
134 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.66999218 |
135 | Wormian bones (HP:0002645) | 1.66874846 |
136 | Hypoglycemic seizures (HP:0002173) | 1.66475504 |
137 | Neurofibrillary tangles (HP:0002185) | 1.66190227 |
138 | Ectopia lentis (HP:0001083) | 1.65403449 |
139 | Arterial tortuosity (HP:0005116) | 1.64789743 |
140 | EMG: neuropathic changes (HP:0003445) | 1.64486371 |
141 | Bowed forearm bones (HP:0003956) | 1.63602346 |
142 | Bowing of the arm (HP:0006488) | 1.63602346 |
143 | Round ear (HP:0100830) | 1.63564911 |
144 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.63179261 |
145 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.62824567 |
146 | Patellar dislocation (HP:0002999) | 1.62646349 |
147 | Abnormality of the calf musculature (HP:0001430) | 1.62562096 |
148 | Insulin resistance (HP:0000855) | 1.62133589 |
149 | Radial bowing (HP:0002986) | 1.62111205 |
150 | Congenital glaucoma (HP:0001087) | 1.61550900 |
151 | Abnormality of purine metabolism (HP:0004352) | 1.61458978 |
152 | Complement deficiency (HP:0004431) | 1.60951145 |
153 | Joint stiffness (HP:0001387) | 1.60643555 |
154 | Muscle stiffness (HP:0003552) | 1.60541752 |
155 | Bowel diverticulosis (HP:0005222) | 1.60368119 |
156 | Biconcave vertebral bodies (HP:0004586) | 1.57363325 |
157 | Mitral stenosis (HP:0001718) | 1.57344607 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 5.28604730 |
2 | ERN1 | 4.01970109 |
3 | PKN2 | 3.80848870 |
4 | TTN | 3.68622821 |
5 | PRPF4B | 3.08667694 |
6 | IRAK3 | 2.97882822 |
7 | SMG1 | 2.86058651 |
8 | NME2 | 2.58941449 |
9 | SIK1 | 2.57489516 |
10 | RIPK1 | 2.45241788 |
11 | PDGFRA | 2.22350638 |
12 | PTK6 | 2.22167188 |
13 | BCKDK | 2.04962655 |
14 | EEF2K | 1.95538239 |
15 | ARAF | 1.80641143 |
16 | SCYL2 | 1.77939169 |
17 | TESK2 | 1.71367354 |
18 | TBK1 | 1.62142398 |
19 | MAP3K10 | 1.61881739 |
20 | FLT3 | 1.56360177 |
21 | DDR2 | 1.55274948 |
22 | PTK2 | 1.45787999 |
23 | PRKD2 | 1.44790761 |
24 | CAMK1D | 1.41800160 |
25 | PIM2 | 1.39205478 |
26 | MAP2K3 | 1.38573345 |
27 | LRRK2 | 1.35788709 |
28 | FGFR4 | 1.34607826 |
29 | NEK1 | 1.27064319 |
30 | BMX | 1.23718316 |
31 | PHKG2 | 1.20417535 |
32 | PHKG1 | 1.20417535 |
33 | LATS2 | 1.19517702 |
34 | LMTK2 | 1.17852080 |
35 | LATS1 | 1.17806297 |
36 | PAK4 | 1.17504367 |
37 | TAOK1 | 1.17411767 |
38 | RIPK4 | 1.15183647 |
39 | TESK1 | 1.12924266 |
40 | CAMK1G | 1.08717944 |
41 | EPHB1 | 1.07905201 |
42 | DMPK | 1.05507363 |
43 | TGFBR2 | 1.01908978 |
44 | MST1R | 0.98947239 |
45 | MET | 0.98347027 |
46 | PDK4 | 0.98305595 |
47 | PDK3 | 0.98305595 |
48 | KSR2 | 0.97363537 |
49 | RPS6KA4 | 0.95501721 |
50 | MTOR | 0.95491401 |
51 | KDR | 0.95175254 |
52 | IRAK2 | 0.95097913 |
53 | ICK | 0.94745150 |
54 | NTRK1 | 0.92391965 |
55 | FER | 0.91278843 |
56 | MAP3K3 | 0.91123664 |
57 | BRAF | 0.90586114 |
58 | PAK3 | 0.88640004 |
59 | RET | 0.85427575 |
60 | PAK2 | 0.84175962 |
61 | MAP3K11 | 0.83918600 |
62 | CAMKK1 | 0.83843702 |
63 | MAP3K1 | 0.83394071 |
64 | JAK1 | 0.83338057 |
65 | PRKD1 | 0.82965775 |
66 | MAP3K7 | 0.78365331 |
67 | HIPK2 | 0.76863923 |
68 | MAP3K13 | 0.75726275 |
69 | STK38 | 0.75501986 |
70 | EPHA3 | 0.74790386 |
71 | PRKD3 | 0.74716039 |
72 | IRAK4 | 0.72883781 |
73 | DAPK3 | 0.72834367 |
74 | MAP4K1 | 0.70579899 |
75 | ILK | 0.69885488 |
76 | CDC42BPA | 0.69560262 |
77 | MAPKAPK3 | 0.67448720 |
78 | EPHA2 | 0.67212446 |
79 | MOS | 0.67042718 |
80 | EPHB2 | 0.65200448 |
81 | WNK4 | 0.64834380 |
82 | INSRR | 0.64578225 |
83 | PRKCH | 0.64417063 |
84 | MAP2K1 | 0.64068845 |
85 | PIK3CG | 0.63905788 |
86 | PDK2 | 0.63471604 |
87 | ALK | 0.62633143 |
88 | PDGFRB | 0.60947347 |
89 | ZAP70 | 0.60796549 |
90 | MAP3K6 | 0.60560202 |
91 | MAPK11 | 0.60133216 |
92 | RPS6KL1 | 0.59908617 |
93 | TNK2 | 0.59580721 |
94 | MAP3K2 | 0.59068782 |
95 | PDPK1 | 0.57987351 |
96 | RPS6KA2 | 0.57430001 |
97 | CAMKK2 | 0.57363631 |
98 | OBSCN | 0.56285700 |
99 | MAPK12 | 0.55960858 |
100 | JAK2 | 0.55424781 |
101 | DYRK1B | 0.55423143 |
102 | MAP2K2 | 0.55085409 |
103 | MYLK | 0.52378540 |
104 | ABL2 | 0.51777251 |
105 | MAP3K8 | 0.49640828 |
106 | CDK7 | 0.48404273 |
107 | PRKAA1 | 0.47901959 |
108 | PDK1 | 0.47038687 |
109 | GRK6 | 0.46997709 |
110 | PRKCI | 0.46764433 |
111 | TAOK2 | 0.46587807 |
112 | RAF1 | 0.46333362 |
113 | LIMK1 | 0.43441736 |
114 | PRKG2 | 0.42042548 |
115 | AKT2 | 0.41583311 |
116 | ROCK1 | 0.41110729 |
117 | RPS6KB2 | 0.40488671 |
118 | NEK9 | 0.39564920 |
119 | TYK2 | 0.39254321 |
120 | PAK6 | 0.39127265 |
121 | FGFR1 | 0.38752721 |
122 | CAMK2G | 0.38347147 |
123 | SIK2 | 0.38268968 |
124 | MARK2 | 0.37142357 |
125 | RPS6KA6 | 0.36621593 |
126 | PAK1 | 0.36523224 |
127 | TAOK3 | 0.35784977 |
128 | CDK12 | 0.35712370 |
129 | AURKA | 0.35216069 |
130 | DAPK2 | 0.35123363 |
131 | CAMK4 | 0.34262377 |
132 | CDK11A | 0.33137580 |
133 | PASK | 0.33087185 |
134 | STK10 | 0.31380422 |
135 | RPS6KC1 | 0.31352156 |
136 | SIK3 | 0.31261683 |
137 | JAK3 | 0.30284024 |
138 | CDK15 | 0.29606266 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.99768064 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.83362494 |
3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.70998517 |
4 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.20888057 |
5 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.04358396 |
6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.95244104 |
7 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.90609213 |
8 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.72310870 |
9 | Carbon metabolism_Homo sapiens_hsa01200 | 1.66977851 |
10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.64977642 |
11 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.56611584 |
12 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.54501013 |
13 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.54315350 |
14 | Insulin resistance_Homo sapiens_hsa04931 | 1.53999755 |
15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.52678143 |
16 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.49356355 |
17 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.43503625 |
18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.39356249 |
19 | Focal adhesion_Homo sapiens_hsa04510 | 1.38289004 |
20 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.37410545 |
21 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.35230896 |
22 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.34938851 |
23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.34424658 |
24 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.30143215 |
25 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.28908488 |
26 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.28478593 |
27 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.26638217 |
28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.26519891 |
29 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.26491463 |
30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.26305528 |
31 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.24125000 |
32 | Endometrial cancer_Homo sapiens_hsa05213 | 1.23616576 |
33 | Lysosome_Homo sapiens_hsa04142 | 1.23071609 |
34 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.21319664 |
35 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.21097983 |
36 | Thyroid cancer_Homo sapiens_hsa05216 | 1.20136714 |
37 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.20113784 |
38 | Galactose metabolism_Homo sapiens_hsa00052 | 1.18952610 |
39 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.17228768 |
40 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.16743877 |
41 | Amoebiasis_Homo sapiens_hsa05146 | 1.15836139 |
42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.14941510 |
43 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.13332101 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 1.13311994 |
45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.12353553 |
46 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.08716177 |
47 | Bladder cancer_Homo sapiens_hsa05219 | 1.08447647 |
48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.07663753 |
49 | Other glycan degradation_Homo sapiens_hsa00511 | 1.06873418 |
50 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.06489143 |
51 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.06057651 |
52 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.04773784 |
53 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.04153541 |
54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.04117933 |
55 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.01612302 |
56 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.01007164 |
57 | Bile secretion_Homo sapiens_hsa04976 | 0.99697240 |
58 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.99479976 |
59 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.99411138 |
60 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.97877546 |
61 | Hepatitis C_Homo sapiens_hsa05160 | 0.96742723 |
62 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.96240493 |
63 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.96085455 |
64 | Shigellosis_Homo sapiens_hsa05131 | 0.95775208 |
65 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.94876714 |
66 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.94656918 |
67 | Salmonella infection_Homo sapiens_hsa05132 | 0.93479114 |
68 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.88843616 |
69 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.88636505 |
70 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.87798642 |
71 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.87595776 |
72 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.87150203 |
73 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.87092925 |
74 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.86586213 |
75 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.86194557 |
76 | Apoptosis_Homo sapiens_hsa04210 | 0.85694617 |
77 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.85222493 |
78 | Hepatitis B_Homo sapiens_hsa05161 | 0.82870993 |
79 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.81859168 |
80 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.80112939 |
81 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.79967039 |
82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.78366526 |
83 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.77603946 |
84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.77169723 |
85 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76969404 |
86 | Prostate cancer_Homo sapiens_hsa05215 | 0.75528990 |
87 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.73131278 |
88 | Prion diseases_Homo sapiens_hsa05020 | 0.72108769 |
89 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.71692388 |
90 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.70618534 |
91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.69377940 |
92 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.68957646 |
93 | Adherens junction_Homo sapiens_hsa04520 | 0.68640291 |
94 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.68548516 |
95 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.67897292 |
96 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.67804686 |
97 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.65344845 |
98 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.65184930 |
99 | Influenza A_Homo sapiens_hsa05164 | 0.62715015 |
100 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.60901330 |
101 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.60690270 |
102 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.59985838 |
103 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.59913804 |
104 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.59873757 |
105 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.59633497 |
106 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.59119868 |
107 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.58433648 |
108 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.57454520 |
109 | HTLV-I infection_Homo sapiens_hsa05166 | 0.56999413 |
110 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56181885 |
111 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.55705307 |
112 | Long-term potentiation_Homo sapiens_hsa04720 | 0.54694414 |
113 | Insulin secretion_Homo sapiens_hsa04911 | 0.53776658 |
114 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.53150551 |
115 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.52866470 |
116 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52729125 |
117 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.52116063 |
118 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.51876336 |
119 | Tuberculosis_Homo sapiens_hsa05152 | 0.51793263 |
120 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.51460070 |
121 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.49828650 |
122 | ABC transporters_Homo sapiens_hsa02010 | 0.49758205 |
123 | Malaria_Homo sapiens_hsa05144 | 0.49513577 |
124 | Peroxisome_Homo sapiens_hsa04146 | 0.49474802 |
125 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48727218 |
126 | Sulfur relay system_Homo sapiens_hsa04122 | 0.48164454 |
127 | Leishmaniasis_Homo sapiens_hsa05140 | 0.48156930 |
128 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.47945510 |
129 | Pertussis_Homo sapiens_hsa05133 | 0.47833618 |
130 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.47825444 |
131 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.47342671 |
132 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.46578666 |
133 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.46398943 |
134 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.45820662 |
135 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.45352611 |
136 | Glioma_Homo sapiens_hsa05214 | 0.44550653 |
137 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.44439923 |
138 | Endocytosis_Homo sapiens_hsa04144 | 0.44384670 |
139 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.44274072 |
140 | Legionellosis_Homo sapiens_hsa05134 | 0.43564752 |
141 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.43398744 |
142 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.42254856 |
143 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.41425045 |