

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of thymocyte apoptotic process (GO:0070244) | 6.00033295 |
| 2 | proteasome assembly (GO:0043248) | 4.92410958 |
| 3 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.91692061 |
| 4 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 4.89240158 |
| 5 | negative regulation of neurological system process (GO:0031645) | 4.71526498 |
| 6 | histamine secretion (GO:0001821) | 4.51250865 |
| 7 | DNA deamination (GO:0045006) | 4.30791393 |
| 8 | tryptophan catabolic process (GO:0006569) | 4.16102992 |
| 9 | indole-containing compound catabolic process (GO:0042436) | 4.16102992 |
| 10 | indolalkylamine catabolic process (GO:0046218) | 4.16102992 |
| 11 | adenosine metabolic process (GO:0046085) | 4.09751285 |
| 12 | neural tube formation (GO:0001841) | 4.03262815 |
| 13 | platelet dense granule organization (GO:0060155) | 4.00960701 |
| 14 | kynurenine metabolic process (GO:0070189) | 4.00865971 |
| 15 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.95942913 |
| 16 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.95942913 |
| 17 | tryptophan metabolic process (GO:0006568) | 3.91042102 |
| 18 | respiratory chain complex IV assembly (GO:0008535) | 3.85683320 |
| 19 | aggressive behavior (GO:0002118) | 3.82465204 |
| 20 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.77996862 |
| 21 | behavioral response to nicotine (GO:0035095) | 3.66917742 |
| 22 | cytochrome complex assembly (GO:0017004) | 3.66083915 |
| 23 | lactate metabolic process (GO:0006089) | 3.59111767 |
| 24 | regulation of podosome assembly (GO:0071801) | 3.58495985 |
| 25 | histamine transport (GO:0051608) | 3.48715873 |
| 26 | kidney morphogenesis (GO:0060993) | 3.44624188 |
| 27 | cornea development in camera-type eye (GO:0061303) | 3.38348858 |
| 28 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.36094644 |
| 29 | regulation of glucokinase activity (GO:0033131) | 3.34508278 |
| 30 | regulation of hexokinase activity (GO:1903299) | 3.34508278 |
| 31 | protein-cofactor linkage (GO:0018065) | 3.33755019 |
| 32 | Peyers patch development (GO:0048541) | 3.33552921 |
| 33 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.33552921 |
| 34 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.31640169 |
| 35 | protein prenylation (GO:0018342) | 3.25573758 |
| 36 | prenylation (GO:0097354) | 3.25573758 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.23157533 |
| 38 | gamma-aminobutyric acid transport (GO:0015812) | 3.22902625 |
| 39 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.22226833 |
| 40 | L-fucose catabolic process (GO:0042355) | 3.21400362 |
| 41 | fucose catabolic process (GO:0019317) | 3.21400362 |
| 42 | L-fucose metabolic process (GO:0042354) | 3.21400362 |
| 43 | amine catabolic process (GO:0009310) | 3.20416054 |
| 44 | cellular biogenic amine catabolic process (GO:0042402) | 3.20416054 |
| 45 | positive regulation of defense response to virus by host (GO:0002230) | 3.19955723 |
| 46 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.18479927 |
| 47 | regulation of thymocyte apoptotic process (GO:0070243) | 3.12468708 |
| 48 | histone mRNA catabolic process (GO:0071044) | 3.12312673 |
| 49 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.12269883 |
| 50 | indolalkylamine metabolic process (GO:0006586) | 3.11954003 |
| 51 | coenzyme catabolic process (GO:0009109) | 3.10727778 |
| 52 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.09975781 |
| 53 | activated T cell proliferation (GO:0050798) | 3.09561809 |
| 54 | cytidine metabolic process (GO:0046087) | 3.09362584 |
| 55 | cytidine catabolic process (GO:0006216) | 3.09362584 |
| 56 | cytidine deamination (GO:0009972) | 3.09362584 |
| 57 | photoreceptor cell maintenance (GO:0045494) | 3.06045453 |
| 58 | branched-chain amino acid catabolic process (GO:0009083) | 3.02301201 |
| 59 | positive regulation of protein homodimerization activity (GO:0090073) | 2.99955656 |
| 60 | L-ascorbic acid metabolic process (GO:0019852) | 2.97676158 |
| 61 | mannosylation (GO:0097502) | 2.97204420 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.96613174 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.96613174 |
| 64 | behavioral response to ethanol (GO:0048149) | 2.95551608 |
| 65 | negative regulation of T cell apoptotic process (GO:0070233) | 2.90144142 |
| 66 | piRNA metabolic process (GO:0034587) | 2.87818443 |
| 67 | artery smooth muscle contraction (GO:0014824) | 2.86278150 |
| 68 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.85907558 |
| 69 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 2.83529684 |
| 70 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.80999195 |
| 71 | protein neddylation (GO:0045116) | 2.80567734 |
| 72 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.80122900 |
| 73 | peroxisome fission (GO:0016559) | 2.78711764 |
| 74 | regulation of relaxation of muscle (GO:1901077) | 2.76534222 |
| 75 | L-methionine salvage (GO:0071267) | 2.75834297 |
| 76 | L-methionine biosynthetic process (GO:0071265) | 2.75834297 |
| 77 | amino acid salvage (GO:0043102) | 2.75834297 |
| 78 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.75205526 |
| 79 | protein targeting to Golgi (GO:0000042) | 2.72618390 |
| 80 | cellular response to ATP (GO:0071318) | 2.70583121 |
| 81 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.70567922 |
| 82 | replication fork processing (GO:0031297) | 2.70141235 |
| 83 | maturation of 5.8S rRNA (GO:0000460) | 2.68692417 |
| 84 | establishment of protein localization to Golgi (GO:0072600) | 2.68243823 |
| 85 | negative regulation of mast cell activation (GO:0033004) | 2.67403704 |
| 86 | response to pheromone (GO:0019236) | 2.67347105 |
| 87 | intracellular protein transmembrane import (GO:0044743) | 2.66622373 |
| 88 | endothelium development (GO:0003158) | 2.66326347 |
| 89 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.65660469 |
| 90 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.64856026 |
| 91 | negative regulation of metanephros development (GO:0072217) | 2.64286855 |
| 92 | aldehyde catabolic process (GO:0046185) | 2.63343184 |
| 93 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.61654689 |
| 94 | branched-chain amino acid metabolic process (GO:0009081) | 2.60055177 |
| 95 | vitamin biosynthetic process (GO:0009110) | 2.58873150 |
| 96 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.58755800 |
| 97 | protein localization to cilium (GO:0061512) | 2.54501578 |
| 98 | protein localization to Golgi apparatus (GO:0034067) | 2.54448562 |
| 99 | epithelial cilium movement (GO:0003351) | 2.52722593 |
| 100 | signal peptide processing (GO:0006465) | 2.52654302 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.84629532 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.28693261 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 2.96799540 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.77011219 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.69638833 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.58856161 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.53333991 |
| 8 | EWS_26573619_Chip-Seq_HEK293_Human | 2.31076227 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.30577118 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.26302304 |
| 11 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.18426116 |
| 12 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.09181832 |
| 13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.07850108 |
| 14 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.87757598 |
| 15 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.87671391 |
| 16 | P300_19829295_ChIP-Seq_ESCs_Human | 1.87601103 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.87493626 |
| 18 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.86256171 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.82616983 |
| 20 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.79806225 |
| 21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.74748069 |
| 22 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.74129914 |
| 23 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.71614739 |
| 24 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.71278042 |
| 25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.70589051 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.70286488 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.69818193 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.67716937 |
| 29 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.66748088 |
| 30 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.65239957 |
| 31 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.63353894 |
| 32 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54833969 |
| 33 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.54113858 |
| 34 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53533660 |
| 35 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.53061299 |
| 36 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.53061299 |
| 37 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.50246269 |
| 38 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.48947090 |
| 39 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.48421825 |
| 40 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.47462086 |
| 41 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.47462086 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.45174982 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.43199772 |
| 44 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.42388188 |
| 45 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.39178174 |
| 46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37128423 |
| 47 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.37095593 |
| 48 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.36826055 |
| 49 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.33481301 |
| 50 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.33481301 |
| 51 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31889814 |
| 52 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.31889814 |
| 53 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29938176 |
| 54 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.28194852 |
| 55 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.28095527 |
| 56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.24702225 |
| 57 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.23108107 |
| 58 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.21567728 |
| 59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.21475223 |
| 60 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.21225059 |
| 61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.20903564 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.19425282 |
| 63 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.18272527 |
| 64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17652853 |
| 65 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.15957211 |
| 66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.15854699 |
| 67 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15285897 |
| 68 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.12432086 |
| 69 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.12415029 |
| 70 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.12027134 |
| 71 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11271209 |
| 72 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.10571018 |
| 73 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.09893169 |
| 74 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.09665819 |
| 75 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.08611095 |
| 76 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.08348903 |
| 77 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.06754623 |
| 78 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05851795 |
| 79 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.04885928 |
| 80 | TCF4_23295773_ChIP-Seq_U87_Human | 1.04729633 |
| 81 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.04626309 |
| 82 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.04009256 |
| 83 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03140372 |
| 84 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.02973457 |
| 85 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02347817 |
| 86 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.02191371 |
| 87 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.01625447 |
| 88 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.01432322 |
| 89 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01271777 |
| 90 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99621681 |
| 91 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.99596684 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.99343338 |
| 93 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.98306094 |
| 94 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98166984 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.97740935 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.96258796 |
| 97 | STAT3_23295773_ChIP-Seq_U87_Human | 0.95869602 |
| 98 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.94969138 |
| 99 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.94411770 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93894653 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009697_abnormal_copulation | 3.55968186 |
| 2 | MP0009780_abnormal_chondrocyte_physiolo | 3.43589597 |
| 3 | MP0006054_spinal_hemorrhage | 3.39694116 |
| 4 | MP0004084_abnormal_cardiac_muscle | 3.16734778 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 2.81963272 |
| 6 | MP0002102_abnormal_ear_morphology | 2.60604725 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.51487383 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.37520893 |
| 9 | MP0004215_abnormal_myocardial_fiber | 2.35302333 |
| 10 | MP0000516_abnormal_urinary_system | 2.23121236 |
| 11 | MP0005367_renal/urinary_system_phenotyp | 2.23121236 |
| 12 | MP0002736_abnormal_nociception_after | 2.15503312 |
| 13 | MP0008875_abnormal_xenobiotic_pharmacok | 2.11738190 |
| 14 | MP0002254_reproductive_system_inflammat | 2.08760860 |
| 15 | MP0005084_abnormal_gallbladder_morpholo | 2.07827927 |
| 16 | MP0003718_maternal_effect | 2.05659317 |
| 17 | MP0001835_abnormal_antigen_presentation | 2.05368635 |
| 18 | MP0003787_abnormal_imprinting | 2.02361531 |
| 19 | MP0008775_abnormal_heart_ventricle | 1.94576427 |
| 20 | MP0005551_abnormal_eye_electrophysiolog | 1.92230535 |
| 21 | MP0002928_abnormal_bile_duct | 1.90424664 |
| 22 | MP0003252_abnormal_bile_duct | 1.88094968 |
| 23 | MP0001984_abnormal_olfaction | 1.84042978 |
| 24 | MP0005253_abnormal_eye_physiology | 1.81718459 |
| 25 | MP0004782_abnormal_surfactant_physiolog | 1.81632478 |
| 26 | MP0002876_abnormal_thyroid_physiology | 1.81508527 |
| 27 | MP0003195_calcinosis | 1.81087134 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.73820064 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.65883247 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.63166659 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.62264306 |
| 32 | MP0001764_abnormal_homeostasis | 1.60734634 |
| 33 | MP0010352_gastrointestinal_tract_polyps | 1.56124165 |
| 34 | MP0008872_abnormal_physiological_respon | 1.55708333 |
| 35 | MP0008058_abnormal_DNA_repair | 1.53363246 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.50177593 |
| 37 | MP0004036_abnormal_muscle_relaxation | 1.47736028 |
| 38 | MP0003186_abnormal_redox_activity | 1.45590036 |
| 39 | MP0005167_abnormal_blood-brain_barrier | 1.42347047 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.39926685 |
| 41 | MP0005671_abnormal_response_to | 1.37611601 |
| 42 | MP0005171_absent_coat_pigmentation | 1.33090879 |
| 43 | MP0001873_stomach_inflammation | 1.30101114 |
| 44 | MP0001501_abnormal_sleep_pattern | 1.28719266 |
| 45 | MP0003011_delayed_dark_adaptation | 1.24331264 |
| 46 | MP0004484_altered_response_of | 1.21441751 |
| 47 | MP0000230_abnormal_systemic_arterial | 1.19654220 |
| 48 | MP0001485_abnormal_pinna_reflex | 1.18484116 |
| 49 | MP0001958_emphysema | 1.18261450 |
| 50 | MP0002234_abnormal_pharynx_morphology | 1.16754936 |
| 51 | MP0005377_hearing/vestibular/ear_phenot | 1.16522347 |
| 52 | MP0003878_abnormal_ear_physiology | 1.16522347 |
| 53 | MP0002148_abnormal_hypersensitivity_rea | 1.16204300 |
| 54 | MP0010368_abnormal_lymphatic_system | 1.13960286 |
| 55 | MP0005174_abnormal_tail_pigmentation | 1.09832424 |
| 56 | MP0000427_abnormal_hair_cycle | 1.04734689 |
| 57 | MP0002095_abnormal_skin_pigmentation | 1.03802704 |
| 58 | MP0000049_abnormal_middle_ear | 1.03419117 |
| 59 | MP0002272_abnormal_nervous_system | 1.03237904 |
| 60 | MP0009785_altered_susceptibility_to | 1.01865370 |
| 61 | MP0005165_increased_susceptibility_to | 1.01380321 |
| 62 | MP0008004_abnormal_stomach_pH | 0.98130735 |
| 63 | MP0002938_white_spotting | 0.96845008 |
| 64 | MP0006072_abnormal_retinal_apoptosis | 0.95291417 |
| 65 | MP0001324_abnormal_eye_pigmentation | 0.94064522 |
| 66 | MP0009764_decreased_sensitivity_to | 0.92001402 |
| 67 | MP0005410_abnormal_fertilization | 0.91908763 |
| 68 | MP0010155_abnormal_intestine_physiology | 0.90624363 |
| 69 | MP0009333_abnormal_splenocyte_physiolog | 0.89037894 |
| 70 | MP0005647_abnormal_sex_gland | 0.88986859 |
| 71 | MP0003880_abnormal_central_pattern | 0.88984756 |
| 72 | MP0009046_muscle_twitch | 0.87054784 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.86899374 |
| 74 | MP0002751_abnormal_autonomic_nervous | 0.86829923 |
| 75 | MP0000371_diluted_coat_color | 0.86696920 |
| 76 | MP0000569_abnormal_digit_pigmentation | 0.86264171 |
| 77 | MP0009765_abnormal_xenobiotic_induced | 0.86187911 |
| 78 | MP0001270_distended_abdomen | 0.85597264 |
| 79 | MP0005379_endocrine/exocrine_gland_phen | 0.81592185 |
| 80 | MP0005395_other_phenotype | 0.80534772 |
| 81 | MP0008007_abnormal_cellular_replicative | 0.80486206 |
| 82 | MP0010234_abnormal_vibrissa_follicle | 0.79328017 |
| 83 | MP0003724_increased_susceptibility_to | 0.76848610 |
| 84 | MP0001486_abnormal_startle_reflex | 0.76707105 |
| 85 | MP0001905_abnormal_dopamine_level | 0.75384943 |
| 86 | MP0004885_abnormal_endolymph | 0.74967756 |
| 87 | MP0002405_respiratory_system_inflammati | 0.73899976 |
| 88 | MP0002090_abnormal_vision | 0.73142132 |
| 89 | MP0010678_abnormal_skin_adnexa | 0.71937661 |
| 90 | MP0002006_tumorigenesis | 0.71243998 |
| 91 | MP0006035_abnormal_mitochondrial_morpho | 0.68989134 |
| 92 | MP0002572_abnormal_emotion/affect_behav | 0.68868249 |
| 93 | MP0005464_abnormal_platelet_physiology | 0.68430815 |
| 94 | MP0005408_hypopigmentation | 0.66542235 |
| 95 | MP0009745_abnormal_behavioral_response | 0.65410487 |
| 96 | MP0000383_abnormal_hair_follicle | 0.63723846 |
| 97 | MP0001177_atelectasis | 0.63082732 |
| 98 | MP0003121_genomic_imprinting | 0.63056225 |
| 99 | MP0003448_altered_tumor_morphology | 0.61337907 |
| 100 | MP0003866_abnormal_defecation | 0.60935754 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Tubular atrophy (HP:0000092) | 4.23107273 |
| 2 | Pancreatic fibrosis (HP:0100732) | 4.05538686 |
| 3 | Pancreatic cysts (HP:0001737) | 3.85211596 |
| 4 | Mesangial abnormality (HP:0001966) | 3.82558997 |
| 5 | Opisthotonus (HP:0002179) | 3.69655917 |
| 6 | Abnormality of the renal cortex (HP:0011035) | 3.53456545 |
| 7 | Abolished electroretinogram (ERG) (HP:0000550) | 3.36535340 |
| 8 | Nephronophthisis (HP:0000090) | 3.31324492 |
| 9 | Hypoproteinemia (HP:0003075) | 3.24092871 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.16770661 |
| 11 | Renal cortical cysts (HP:0000803) | 3.12274599 |
| 12 | Thyroid-stimulating hormone excess (HP:0002925) | 3.10599632 |
| 13 | True hermaphroditism (HP:0010459) | 3.08927312 |
| 14 | Neonatal respiratory distress (HP:0002643) | 3.08600967 |
| 15 | Abnormality of the renal medulla (HP:0100957) | 3.06804031 |
| 16 | Cutaneous melanoma (HP:0012056) | 3.06306295 |
| 17 | Dyschromatopsia (HP:0007641) | 2.94717987 |
| 18 | Abnormal biliary tract physiology (HP:0012439) | 2.85755334 |
| 19 | Bile duct proliferation (HP:0001408) | 2.85755334 |
| 20 | Thyroiditis (HP:0100646) | 2.84057198 |
| 21 | Hemiparesis (HP:0001269) | 2.79605107 |
| 22 | Abnormal drinking behavior (HP:0030082) | 2.77251027 |
| 23 | Polydipsia (HP:0001959) | 2.77251027 |
| 24 | Dry hair (HP:0011359) | 2.69952949 |
| 25 | Increased CSF lactate (HP:0002490) | 2.63540476 |
| 26 | Nausea (HP:0002018) | 2.62459943 |
| 27 | Redundant skin (HP:0001582) | 2.58636703 |
| 28 | 3-Methylglutaconic aciduria (HP:0003535) | 2.49728390 |
| 29 | Unilateral renal agenesis (HP:0000122) | 2.44151652 |
| 30 | Hypoplastic pelvis (HP:0008839) | 2.43875814 |
| 31 | Cystic liver disease (HP:0006706) | 2.42880473 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.42207182 |
| 33 | Polyuria (HP:0000103) | 2.40947866 |
| 34 | Increased serum pyruvate (HP:0003542) | 2.39554281 |
| 35 | Hypoalbuminemia (HP:0003073) | 2.38427484 |
| 36 | Abnormal albumin level (HP:0012116) | 2.38427484 |
| 37 | Inability to walk (HP:0002540) | 2.36979941 |
| 38 | Widely patent fontanelles and sutures (HP:0004492) | 2.36662847 |
| 39 | Tubulointerstitial abnormality (HP:0001969) | 2.33438944 |
| 40 | Methylmalonic acidemia (HP:0002912) | 2.30120843 |
| 41 | Progressive microcephaly (HP:0000253) | 2.27023848 |
| 42 | Decreased central vision (HP:0007663) | 2.26700203 |
| 43 | Congenital hepatic fibrosis (HP:0002612) | 2.24111140 |
| 44 | Hyperglycinuria (HP:0003108) | 2.24076795 |
| 45 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.23100379 |
| 46 | Optic disc pallor (HP:0000543) | 2.20610028 |
| 47 | Tubulointerstitial nephritis (HP:0001970) | 2.19952630 |
| 48 | Horizontal nystagmus (HP:0000666) | 2.18430595 |
| 49 | Attenuation of retinal blood vessels (HP:0007843) | 2.17746862 |
| 50 | Menstrual irregularities (HP:0000858) | 2.17371374 |
| 51 | Increased serum lactate (HP:0002151) | 2.17063583 |
| 52 | Hyperglycinemia (HP:0002154) | 2.16769768 |
| 53 | Pendular nystagmus (HP:0012043) | 2.16208142 |
| 54 | Mitochondrial inheritance (HP:0001427) | 2.16031020 |
| 55 | Progressive macrocephaly (HP:0004481) | 2.15110130 |
| 56 | Abnormality of alanine metabolism (HP:0010916) | 2.13844642 |
| 57 | Hyperalaninemia (HP:0003348) | 2.13844642 |
| 58 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.13844642 |
| 59 | Supernumerary spleens (HP:0009799) | 2.13325255 |
| 60 | Increased corneal curvature (HP:0100692) | 2.12891588 |
| 61 | Keratoconus (HP:0000563) | 2.12891588 |
| 62 | Septo-optic dysplasia (HP:0100842) | 2.10856227 |
| 63 | Anhidrosis (HP:0000970) | 2.08467691 |
| 64 | Gaze-evoked nystagmus (HP:0000640) | 2.05770403 |
| 65 | Hepatocellular necrosis (HP:0001404) | 2.05264143 |
| 66 | Hypoplasia of the fovea (HP:0007750) | 2.05247718 |
| 67 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.05247718 |
| 68 | Decreased lacrimation (HP:0000633) | 2.05206687 |
| 69 | Adrenal hypoplasia (HP:0000835) | 2.04261208 |
| 70 | Spontaneous abortion (HP:0005268) | 2.03958148 |
| 71 | Tubulointerstitial fibrosis (HP:0005576) | 2.03949465 |
| 72 | Spastic paraparesis (HP:0002313) | 2.01736993 |
| 73 | Type I transferrin isoform profile (HP:0003642) | 2.00118150 |
| 74 | Hepatic necrosis (HP:0002605) | 2.00113806 |
| 75 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.98470737 |
| 76 | Facial diplegia (HP:0001349) | 1.95306347 |
| 77 | Hyperventilation (HP:0002883) | 1.94240695 |
| 78 | Poor head control (HP:0002421) | 1.92129298 |
| 79 | Acute necrotizing encephalopathy (HP:0006965) | 1.91496355 |
| 80 | Delayed gross motor development (HP:0002194) | 1.88713751 |
| 81 | Ependymoma (HP:0002888) | 1.88154907 |
| 82 | Hyperthyroidism (HP:0000836) | 1.88102300 |
| 83 | Abnormality of B cell number (HP:0010975) | 1.87829012 |
| 84 | Potter facies (HP:0002009) | 1.87144883 |
| 85 | Facial shape deformation (HP:0011334) | 1.87144883 |
| 86 | Lipid accumulation in hepatocytes (HP:0006561) | 1.84578337 |
| 87 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.83831327 |
| 88 | Abnormal urine output (HP:0012590) | 1.82815361 |
| 89 | Panhypogammaglobulinemia (HP:0003139) | 1.82368208 |
| 90 | CNS demyelination (HP:0007305) | 1.82147273 |
| 91 | Asplenia (HP:0001746) | 1.81512803 |
| 92 | Furrowed tongue (HP:0000221) | 1.80149490 |
| 93 | Abnormal auditory evoked potentials (HP:0006958) | 1.80056352 |
| 94 | Sclerocornea (HP:0000647) | 1.79774837 |
| 95 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.79314989 |
| 96 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.79159638 |
| 97 | Abnormality of glycine metabolism (HP:0010895) | 1.79104594 |
| 98 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.79104594 |
| 99 | Autoimmune thrombocytopenia (HP:0001973) | 1.78869588 |
| 100 | Acute encephalopathy (HP:0006846) | 1.78448275 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.16121548 |
| 2 | MST4 | 4.01787655 |
| 3 | TAOK3 | 3.75971606 |
| 4 | TIE1 | 3.19512887 |
| 5 | TXK | 3.12106724 |
| 6 | MAP4K2 | 2.96703128 |
| 7 | NUAK1 | 2.33108071 |
| 8 | PINK1 | 2.12576861 |
| 9 | ZAK | 2.01632078 |
| 10 | WNK3 | 1.89491111 |
| 11 | GRK1 | 1.87364571 |
| 12 | TLK1 | 1.85868901 |
| 13 | TSSK6 | 1.78956641 |
| 14 | EPHA3 | 1.76776756 |
| 15 | ADRBK2 | 1.76134601 |
| 16 | MAP3K14 | 1.75674070 |
| 17 | BMPR1B | 1.74624722 |
| 18 | NEK1 | 1.73515164 |
| 19 | EIF2AK3 | 1.70431307 |
| 20 | TRIM28 | 1.62972953 |
| 21 | ERBB3 | 1.48845925 |
| 22 | PTK2B | 1.48543077 |
| 23 | BCR | 1.36001035 |
| 24 | MAPK13 | 1.31395256 |
| 25 | PHKG1 | 1.28158209 |
| 26 | PHKG2 | 1.28158209 |
| 27 | STK38L | 1.26706984 |
| 28 | PBK | 1.23287830 |
| 29 | STK3 | 1.18855038 |
| 30 | TEC | 1.15809684 |
| 31 | ACVR1B | 1.14739118 |
| 32 | PLK3 | 1.12479612 |
| 33 | STK39 | 1.11026718 |
| 34 | ADRBK1 | 1.08714865 |
| 35 | FGFR2 | 1.07205704 |
| 36 | RPS6KA5 | 1.06646351 |
| 37 | FER | 1.06067767 |
| 38 | PLK2 | 1.05902674 |
| 39 | TGFBR1 | 1.03498130 |
| 40 | LIMK1 | 1.02217077 |
| 41 | PAK3 | 1.01341578 |
| 42 | CSNK1G3 | 0.97751607 |
| 43 | STK16 | 0.96998923 |
| 44 | IKBKB | 0.95884819 |
| 45 | PRKCE | 0.95149923 |
| 46 | OXSR1 | 0.92589648 |
| 47 | BCKDK | 0.91879678 |
| 48 | LATS1 | 0.91104533 |
| 49 | EIF2AK1 | 0.88728407 |
| 50 | PNCK | 0.88698869 |
| 51 | CSNK1G2 | 0.88334059 |
| 52 | MKNK1 | 0.86519490 |
| 53 | CASK | 0.84272468 |
| 54 | KIT | 0.82789946 |
| 55 | STK10 | 0.82066036 |
| 56 | CSNK1A1L | 0.80392642 |
| 57 | CSNK1G1 | 0.76442766 |
| 58 | TNK2 | 0.72461382 |
| 59 | PRKG2 | 0.68443831 |
| 60 | IRAK1 | 0.66544718 |
| 61 | PRKCQ | 0.65656343 |
| 62 | MAPKAPK5 | 0.64039658 |
| 63 | WNK4 | 0.63353637 |
| 64 | CHUK | 0.59136640 |
| 65 | DYRK3 | 0.59044260 |
| 66 | PRKD3 | 0.58381847 |
| 67 | VRK1 | 0.53348070 |
| 68 | NLK | 0.52136716 |
| 69 | TGFBR2 | 0.50639528 |
| 70 | DAPK2 | 0.49628268 |
| 71 | ROCK1 | 0.49278144 |
| 72 | FGFR3 | 0.47466427 |
| 73 | ALK | 0.47351175 |
| 74 | MARK1 | 0.45227934 |
| 75 | MAP4K1 | 0.44574631 |
| 76 | BUB1 | 0.43945984 |
| 77 | CCNB1 | 0.43173153 |
| 78 | CAMK2A | 0.40420515 |
| 79 | MATK | 0.40182270 |
| 80 | MAPK15 | 0.39758366 |
| 81 | JAK3 | 0.37374033 |
| 82 | CAMK2D | 0.37195597 |
| 83 | IKBKE | 0.36016670 |
| 84 | PRKCI | 0.35684961 |
| 85 | INSRR | 0.35246861 |
| 86 | PLK1 | 0.34979035 |
| 87 | PRKG1 | 0.34281615 |
| 88 | PASK | 0.33966246 |
| 89 | ABL1 | 0.32734576 |
| 90 | SIK3 | 0.32627444 |
| 91 | PRKCG | 0.31608223 |
| 92 | ROCK2 | 0.31292394 |
| 93 | MINK1 | 0.31259036 |
| 94 | PRKACA | 0.29339621 |
| 95 | WEE1 | 0.28827555 |
| 96 | CDC7 | 0.28417261 |
| 97 | NME1 | 0.27686840 |
| 98 | LCK | 0.27615719 |
| 99 | IGF1R | 0.26985811 |
| 100 | BTK | 0.26395797 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protein export_Homo sapiens_hsa03060 | 4.19988447 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.97537722 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.34123970 |
| 4 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.22691367 |
| 5 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.12134717 |
| 6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.98493344 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 1.93936672 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.88989935 |
| 9 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.88720378 |
| 10 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.88697910 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.86485294 |
| 12 | Phototransduction_Homo sapiens_hsa04744 | 1.84142024 |
| 13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.81664307 |
| 14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.80660362 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.79579337 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.78471279 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.74944130 |
| 18 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.72836023 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.67182843 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.63912073 |
| 21 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.62412475 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62291990 |
| 23 | Homologous recombination_Homo sapiens_hsa03440 | 1.49956376 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47313839 |
| 25 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.45656176 |
| 26 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.43136176 |
| 27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.40945289 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.39149328 |
| 29 | Olfactory transduction_Homo sapiens_hsa04740 | 1.35597432 |
| 30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.32437555 |
| 31 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.30172961 |
| 32 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.29967700 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 1.23719284 |
| 34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.18375028 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.13479594 |
| 36 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.10750853 |
| 37 | Parkinsons disease_Homo sapiens_hsa05012 | 1.08153359 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06762080 |
| 39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.06745104 |
| 40 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.04809508 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.01675782 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.99880437 |
| 43 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.99226154 |
| 44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.98839286 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.95338551 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.91132911 |
| 47 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.88310640 |
| 48 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86419468 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85538366 |
| 50 | Allograft rejection_Homo sapiens_hsa05330 | 0.81504611 |
| 51 | Purine metabolism_Homo sapiens_hsa00230 | 0.81491673 |
| 52 | Circadian entrainment_Homo sapiens_hsa04713 | 0.80942238 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.79526239 |
| 54 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.79518874 |
| 55 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.77912603 |
| 56 | Taste transduction_Homo sapiens_hsa04742 | 0.76865798 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76046117 |
| 58 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.75825190 |
| 59 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.74678916 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.73639938 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71993448 |
| 62 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.70906807 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70172851 |
| 64 | Mismatch repair_Homo sapiens_hsa03430 | 0.69798080 |
| 65 | Morphine addiction_Homo sapiens_hsa05032 | 0.68708479 |
| 66 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.67533054 |
| 67 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.66503173 |
| 68 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66288946 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.65111678 |
| 70 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64291804 |
| 71 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61964747 |
| 72 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.60329543 |
| 73 | Renin secretion_Homo sapiens_hsa04924 | 0.59793428 |
| 74 | Salivary secretion_Homo sapiens_hsa04970 | 0.58836028 |
| 75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.57196347 |
| 76 | GABAergic synapse_Homo sapiens_hsa04727 | 0.56726188 |
| 77 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.54923501 |
| 78 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.54918726 |
| 79 | ABC transporters_Homo sapiens_hsa02010 | 0.53898869 |
| 80 | Alzheimers disease_Homo sapiens_hsa05010 | 0.53244348 |
| 81 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.51475826 |
| 82 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.50350589 |
| 83 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50289328 |
| 84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50265768 |
| 85 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.50243239 |
| 86 | Nicotine addiction_Homo sapiens_hsa05033 | 0.49959701 |
| 87 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49723004 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.47255986 |
| 89 | Insulin secretion_Homo sapiens_hsa04911 | 0.45889073 |
| 90 | Huntingtons disease_Homo sapiens_hsa05016 | 0.45513507 |
| 91 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.43983272 |
| 92 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.43820287 |
| 93 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.43205868 |
| 94 | Malaria_Homo sapiens_hsa05144 | 0.42855288 |
| 95 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.40437233 |
| 96 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39891387 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.38966116 |
| 98 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.38335312 |
| 99 | Circadian rhythm_Homo sapiens_hsa04710 | 0.37170145 |
| 100 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.36035885 |

