SDHAF4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.12546136
2ATP synthesis coupled proton transport (GO:0015986)7.82475379
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.82475379
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.52488503
5respiratory electron transport chain (GO:0022904)6.50455018
6electron transport chain (GO:0022900)6.37439791
7chaperone-mediated protein transport (GO:0072321)5.44907190
8protein complex biogenesis (GO:0070271)5.12127955
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.97047425
10mitochondrial respiratory chain complex I assembly (GO:0032981)4.97047425
11NADH dehydrogenase complex assembly (GO:0010257)4.97047425
12protein neddylation (GO:0045116)4.86686860
13behavioral response to nicotine (GO:0035095)4.73992029
14GTP biosynthetic process (GO:0006183)4.58613194
15mitochondrial respiratory chain complex assembly (GO:0033108)4.49254002
16hydrogen ion transmembrane transport (GO:1902600)4.20917345
17establishment of protein localization to mitochondrial membrane (GO:0090151)4.18616731
18purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.09912614
19purine nucleoside triphosphate biosynthetic process (GO:0009145)4.03551024
20ATP biosynthetic process (GO:0006754)3.95998163
21respiratory chain complex IV assembly (GO:0008535)3.92457787
22dopamine transport (GO:0015872)3.88612990
23proton transport (GO:0015992)3.86452788
24inner mitochondrial membrane organization (GO:0007007)3.86017264
25hydrogen transport (GO:0006818)3.78369888
26UTP biosynthetic process (GO:0006228)3.61745987
27proteasome assembly (GO:0043248)3.61402672
28nonmotile primary cilium assembly (GO:0035058)3.55926842
29cytochrome complex assembly (GO:0017004)3.52737999
30epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.52689726
31ribonucleoside triphosphate biosynthetic process (GO:0009201)3.49268026
32cullin deneddylation (GO:0010388)3.46691285
33platelet dense granule organization (GO:0060155)3.43562515
34cellular ketone body metabolic process (GO:0046950)3.41772745
35water-soluble vitamin biosynthetic process (GO:0042364)3.39910793
36L-fucose catabolic process (GO:0042355)3.39524173
37fucose catabolic process (GO:0019317)3.39524173
38L-fucose metabolic process (GO:0042354)3.39524173
39protein localization to cilium (GO:0061512)3.38931130
40neuron cell-cell adhesion (GO:0007158)3.34573980
41response to pheromone (GO:0019236)3.31392343
42energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.29838295
43ATP hydrolysis coupled proton transport (GO:0015991)3.29838295
44guanosine-containing compound biosynthetic process (GO:1901070)3.29586817
45regulation of mitochondrial translation (GO:0070129)3.27722295
46oxidative phosphorylation (GO:0006119)3.20049524
47intraciliary transport (GO:0042073)3.18426251
48protein deneddylation (GO:0000338)3.16463906
49aerobic respiration (GO:0009060)3.13636591
50mannosylation (GO:0097502)3.13159074
51long-chain fatty acid biosynthetic process (GO:0042759)3.11136208
52presynaptic membrane assembly (GO:0097105)3.10339636
53DNA double-strand break processing (GO:0000729)3.08557619
54pyrimidine nucleobase catabolic process (GO:0006208)3.07808708
55protein targeting to mitochondrion (GO:0006626)3.06466751
56UTP metabolic process (GO:0046051)3.05383246
57peptidyl-histidine modification (GO:0018202)3.05360970
58ketone body metabolic process (GO:1902224)3.04818610
59nucleoside triphosphate biosynthetic process (GO:0009142)3.03562110
60nucleoside diphosphate phosphorylation (GO:0006165)3.02102936
61central nervous system myelination (GO:0022010)3.00968826
62axon ensheathment in central nervous system (GO:0032291)3.00968826
63CTP biosynthetic process (GO:0006241)3.00742264
64CTP metabolic process (GO:0046036)3.00742264
65regulation of dopamine metabolic process (GO:0042053)3.00736311
66regulation of catecholamine metabolic process (GO:0042069)3.00736311
67fatty acid elongation (GO:0030497)3.00465796
68regulation of oxidative phosphorylation (GO:0002082)2.98873612
69ribosomal small subunit biogenesis (GO:0042274)2.97724703
70establishment of protein localization to mitochondrion (GO:0072655)2.97448355
71protein polyglutamylation (GO:0018095)2.96554990
72sequestering of actin monomers (GO:0042989)2.95566114
73substantia nigra development (GO:0021762)2.93530300
74neuron fate determination (GO:0048664)2.90761267
75termination of RNA polymerase III transcription (GO:0006386)2.89360457
76transcription elongation from RNA polymerase III promoter (GO:0006385)2.89360457
77nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.88473374
78viral protein processing (GO:0019082)2.87136574
79presynaptic membrane organization (GO:0097090)2.84668239
80cilium morphogenesis (GO:0060271)2.83339144
81GPI anchor biosynthetic process (GO:0006506)2.82819152
82positive regulation of mitochondrial fission (GO:0090141)2.82113166
83detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.82098619
84dopamine biosynthetic process (GO:0042416)2.81999906
85tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.80483005
86RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.80483005
87exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.78312594
88indolalkylamine metabolic process (GO:0006586)2.77672973
89signal peptide processing (GO:0006465)2.76044628
90protein localization to mitochondrion (GO:0070585)2.75867342
91negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.74421256
92intracellular protein transmembrane import (GO:0044743)2.74326791
93gamma-aminobutyric acid transport (GO:0015812)2.73092682
94kynurenine metabolic process (GO:0070189)2.72816679
95ubiquinone biosynthetic process (GO:0006744)2.71875819
96quinone biosynthetic process (GO:1901663)2.71875819
97regulation of cellular amino acid metabolic process (GO:0006521)2.71188859
98negative regulation of telomere maintenance (GO:0032205)2.70015602
99DNA deamination (GO:0045006)2.69687711
100cilium organization (GO:0044782)2.69295703
101mitochondrial transport (GO:0006839)2.67073772
102protein-cofactor linkage (GO:0018065)2.66736312
1037-methylguanosine RNA capping (GO:0009452)2.65859174
104RNA capping (GO:0036260)2.65859174
1057-methylguanosine mRNA capping (GO:0006370)2.63679169
106calcium-mediated signaling using intracellular calcium source (GO:0035584)2.63561275
107detection of light stimulus involved in sensory perception (GO:0050962)2.63197230
108detection of light stimulus involved in visual perception (GO:0050908)2.63197230
109cilium assembly (GO:0042384)2.63153033
110tryptophan catabolic process (GO:0006569)2.62833808
111indole-containing compound catabolic process (GO:0042436)2.62833808
112indolalkylamine catabolic process (GO:0046218)2.62833808
113ubiquinone metabolic process (GO:0006743)2.62031231
114cilium movement (GO:0003341)2.61082957
115transmission of nerve impulse (GO:0019226)2.59940612
116negative regulation of response to food (GO:0032096)2.59707905
117negative regulation of appetite (GO:0032099)2.59707905
118nucleobase catabolic process (GO:0046113)2.59184819
119retinal cone cell development (GO:0046549)2.55412611
120regulation of glucokinase activity (GO:0033131)2.54032565
121regulation of hexokinase activity (GO:1903299)2.54032565
122neurotransmitter uptake (GO:0001504)2.53728664
123L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.53579533
124cotranslational protein targeting to membrane (GO:0006613)2.53400388
125transferrin transport (GO:0033572)2.53076132
126negative regulation of neurotransmitter transport (GO:0051589)2.52939206
127axonemal dynein complex assembly (GO:0070286)2.49612973
128catecholamine transport (GO:0051937)2.49457069
129glycerophospholipid catabolic process (GO:0046475)2.48383460
130GPI anchor metabolic process (GO:0006505)2.47456015
131photoreceptor cell maintenance (GO:0045494)2.47406032
132epithelial cilium movement (GO:0003351)2.47268108
133synaptic transmission, cholinergic (GO:0007271)2.46400830
134preassembly of GPI anchor in ER membrane (GO:0016254)2.44969800
135axoneme assembly (GO:0035082)2.44528943
136phagosome maturation (GO:0090382)2.44413548
137quinone metabolic process (GO:1901661)2.44411663
138aldehyde catabolic process (GO:0046185)2.43572451
139protein targeting to ER (GO:0045047)2.43156932
140neuronal action potential (GO:0019228)2.42670057
141positive regulation of protein homodimerization activity (GO:0090073)2.42651042
142protein localization to endoplasmic reticulum (GO:0070972)2.42253685
143positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.42204302
144replication fork processing (GO:0031297)2.40631525
145regulation of cilium movement (GO:0003352)2.40320419
146antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.40255104
147pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.40231041
148C4-dicarboxylate transport (GO:0015740)2.39723630
149somite development (GO:0061053)2.38684725
150somite rostral/caudal axis specification (GO:0032525)2.38340833
151anterograde synaptic vesicle transport (GO:0048490)2.37828495
152kidney morphogenesis (GO:0060993)2.37613686
153neural tube formation (GO:0001841)2.37141308
154spinal cord motor neuron differentiation (GO:0021522)2.35195851
155regulation of action potential (GO:0098900)2.34669330
156retinal ganglion cell axon guidance (GO:0031290)2.34408378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.78523913
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.70362954
3EZH2_22144423_ChIP-Seq_EOC_Human3.47334351
4GBX2_23144817_ChIP-Seq_PC3_Human3.16376635
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.04790044
6TAF15_26573619_Chip-Seq_HEK293_Human2.97114684
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.90938505
8VDR_22108803_ChIP-Seq_LS180_Human2.79138381
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.78842910
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.74773043
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.70574390
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.45730862
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.36533808
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.35863891
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30193906
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.26920932
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.20683185
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.12929399
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12893372
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.07221446
21POU3F2_20337985_ChIP-ChIP_501MEL_Human2.06266834
22FUS_26573619_Chip-Seq_HEK293_Human2.01168262
23PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.95565327
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92848083
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.90190278
26P300_19829295_ChIP-Seq_ESCs_Human1.84287417
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.84274766
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.81726503
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79568030
30IGF1R_20145208_ChIP-Seq_DFB_Human1.72252038
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.72190870
32SRF_21415370_ChIP-Seq_HL-1_Mouse1.71632808
33JARID2_20064375_ChIP-Seq_MESCs_Mouse1.69277509
34MYC_18940864_ChIP-ChIP_HL60_Human1.68639394
35SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.67412481
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.66805870
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.65869208
38EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.60620960
39TP53_22573176_ChIP-Seq_HFKS_Human1.59704711
40ER_23166858_ChIP-Seq_MCF-7_Human1.59106535
41EZH2_27304074_Chip-Seq_ESCs_Mouse1.58853854
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54965758
43ETS1_20019798_ChIP-Seq_JURKAT_Human1.51454138
44FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.48951546
45RNF2_27304074_Chip-Seq_NSC_Mouse1.48380444
46CBP_20019798_ChIP-Seq_JUKART_Human1.45704693
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45704693
48EED_16625203_ChIP-ChIP_MESCs_Mouse1.44456673
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.43290548
50SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.42698859
51IRF1_19129219_ChIP-ChIP_H3396_Human1.42067837
52SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.39880281
53NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.38118800
54BCAT_22108803_ChIP-Seq_LS180_Human1.38021463
55BP1_19119308_ChIP-ChIP_Hs578T_Human1.37593998
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36749897
57CREB1_15753290_ChIP-ChIP_HEK293T_Human1.36000500
58EWS_26573619_Chip-Seq_HEK293_Human1.34867309
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34774708
60SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.34273234
61CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.33923641
62AR_25329375_ChIP-Seq_VCAP_Human1.33745047
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32329298
64JARID2_20075857_ChIP-Seq_MESCs_Mouse1.32158025
65RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.30352838
66SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.30136987
67SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29617186
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28571710
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26033297
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.25476862
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24667647
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24333000
73FOXA1_25329375_ChIP-Seq_VCAP_Human1.24244716
74FOXA1_27270436_Chip-Seq_PROSTATE_Human1.24244716
75ELF1_17652178_ChIP-ChIP_JURKAT_Human1.21595239
76REST_21632747_ChIP-Seq_MESCs_Mouse1.20767933
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.20671575
78PIAS1_25552417_ChIP-Seq_VCAP_Human1.20409942
79SMAD4_21799915_ChIP-Seq_A2780_Human1.16827874
80STAT3_18555785_Chip-Seq_ESCs_Mouse1.15529196
81STAT3_23295773_ChIP-Seq_U87_Human1.15246569
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14927481
83SMAD3_21741376_ChIP-Seq_EPCs_Human1.14531460
84ELK1_19687146_ChIP-ChIP_HELA_Human1.13943604
85PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13628899
86P53_22387025_ChIP-Seq_ESCs_Mouse1.13471675
87TCF4_22108803_ChIP-Seq_LS180_Human1.13274519
88SUZ12_18555785_Chip-Seq_ESCs_Mouse1.12521392
89JUN_21703547_ChIP-Seq_K562_Human1.12392334
90CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.12199287
91SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12108297
92TCF4_23295773_ChIP-Seq_U87_Human1.12079315
93TAL1_26923725_Chip-Seq_HPCs_Mouse1.11565337
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11385220
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10780955
96ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10485483
97SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09830001
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09388449
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09388449
100TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08925753
101MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08844295
102FOXP3_21729870_ChIP-Seq_TREG_Human1.08343177
103EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07153420
104GATA3_21878914_ChIP-Seq_MCF-7_Human1.07069321
105SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.07056598
106NCOR_22424771_ChIP-Seq_293T_Human1.06734800
107EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06434094
108CMYC_18555785_Chip-Seq_ESCs_Mouse1.05957130
109NOTCH1_21737748_ChIP-Seq_TLL_Human1.05345054
110P300_18555785_Chip-Seq_ESCs_Mouse1.05069115
111GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04784205
112AR_20517297_ChIP-Seq_VCAP_Human1.04463298
113MTF2_20144788_ChIP-Seq_MESCs_Mouse1.03971388
114SOX2_18555785_Chip-Seq_ESCs_Mouse1.03655861
115E2F1_18555785_Chip-Seq_ESCs_Mouse1.03591605
116EZH2_18974828_ChIP-Seq_MESCs_Mouse1.03484281
117RNF2_18974828_ChIP-Seq_MESCs_Mouse1.03484281
118RUNX1_27457419_Chip-Seq_LIVER_Mouse1.02616551
119NMYC_18555785_Chip-Seq_ESCs_Mouse1.01787917
120ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.01705912
121RUNX2_22187159_ChIP-Seq_PCA_Human1.01538370
122NFE2_27457419_Chip-Seq_LIVER_Mouse1.01139638
123EZH2_27294783_Chip-Seq_ESCs_Mouse1.01127758
124CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.00716184
125YY1_21170310_ChIP-Seq_MESCs_Mouse1.00411650
126NANOG_19829295_ChIP-Seq_ESCs_Human1.00324168
127SOX2_19829295_ChIP-Seq_ESCs_Human1.00324168
128PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99727472
129CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99699464
130MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99342727
131FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98901513
132DCP1A_22483619_ChIP-Seq_HELA_Human0.98866783
133HTT_18923047_ChIP-ChIP_STHdh_Human0.97959256
134SOX2_16153702_ChIP-ChIP_HESCs_Human0.97816204
135VDR_23849224_ChIP-Seq_CD4+_Human0.97680816
136EZH2_27294783_Chip-Seq_NPCs_Mouse0.97453723
137POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97172059
138ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.97055261
139SMAD4_21741376_ChIP-Seq_EPCs_Human0.96522146
140REST_18959480_ChIP-ChIP_MESCs_Mouse0.96099866

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.60478574
2MP0001529_abnormal_vocalization3.34180559
3MP0009379_abnormal_foot_pigmentation3.22781764
4MP0001905_abnormal_dopamine_level3.01231301
5MP0006276_abnormal_autonomic_nervous2.96008519
6MP0001188_hyperpigmentation2.81022869
7MP0003136_yellow_coat_color2.55795837
8MP0001968_abnormal_touch/_nociception2.47945375
9MP0008877_abnormal_DNA_methylation2.47876332
10MP0002736_abnormal_nociception_after2.47406528
11MP0002638_abnormal_pupillary_reflex2.45191347
12MP0001984_abnormal_olfaction2.39532776
13MP0002837_dystrophic_cardiac_calcinosis2.19631298
14MP0009745_abnormal_behavioral_response2.15819739
15MP0002272_abnormal_nervous_system2.13601224
16MP0006292_abnormal_olfactory_placode2.13236610
17MP0002064_seizures1.98220611
18MP0005645_abnormal_hypothalamus_physiol1.93831419
19MP0002653_abnormal_ependyma_morphology1.93630293
20MP0010386_abnormal_urinary_bladder1.90515252
21MP0005409_darkened_coat_color1.90043442
22MP0002734_abnormal_mechanical_nocicepti1.89595566
23MP0005646_abnormal_pituitary_gland1.89301659
24MP0001440_abnormal_grooming_behavior1.88411582
25MP0004142_abnormal_muscle_tone1.86904780
26MP0002572_abnormal_emotion/affect_behav1.84231094
27MP0003011_delayed_dark_adaptation1.83852062
28MP0009046_muscle_twitch1.83161757
29MP0003635_abnormal_synaptic_transmissio1.82590554
30MP0002735_abnormal_chemical_nociception1.82082032
31MP0004133_heterotaxia1.81394962
32MP0004270_analgesia1.80154234
33MP0001501_abnormal_sleep_pattern1.77807613
34MP0003787_abnormal_imprinting1.76264386
35MP0002876_abnormal_thyroid_physiology1.73764039
36MP0004885_abnormal_endolymph1.69931255
37MP0001486_abnormal_startle_reflex1.68912329
38MP0001986_abnormal_taste_sensitivity1.64825020
39MP0005379_endocrine/exocrine_gland_phen1.61015462
40MP0002063_abnormal_learning/memory/cond1.55017509
41MP0002067_abnormal_sensory_capabilities1.53722633
42MP0008875_abnormal_xenobiotic_pharmacok1.51869442
43MP0000372_irregular_coat_pigmentation1.51587306
44MP0005551_abnormal_eye_electrophysiolog1.47023191
45MP0001970_abnormal_pain_threshold1.46884141
46MP0002822_catalepsy1.46761236
47MP0005171_absent_coat_pigmentation1.45524240
48MP0005423_abnormal_somatic_nervous1.43287584
49MP0000569_abnormal_digit_pigmentation1.40105166
50MP0006035_abnormal_mitochondrial_morpho1.38652001
51MP0006036_abnormal_mitochondrial_physio1.38605355
52MP0009697_abnormal_copulation1.36488967
53MP0003122_maternal_imprinting1.34984095
54MP0002733_abnormal_thermal_nociception1.34541202
55MP0003646_muscle_fatigue1.33733130
56MP0002909_abnormal_adrenal_gland1.33210497
57MP0004742_abnormal_vestibular_system1.32241840
58MP0002163_abnormal_gland_morphology1.31447787
59MP0005386_behavior/neurological_phenoty1.30421561
60MP0004924_abnormal_behavior1.30421561
61MP0000631_abnormal_neuroendocrine_gland1.29583538
62MP0003121_genomic_imprinting1.28313544
63MP0006072_abnormal_retinal_apoptosis1.28134416
64MP0008995_early_reproductive_senescence1.27944573
65MP0000778_abnormal_nervous_system1.26936637
66MP0003283_abnormal_digestive_organ1.23714517
67MP0002234_abnormal_pharynx_morphology1.23634231
68MP0002557_abnormal_social/conspecific_i1.21338240
69MP0002184_abnormal_innervation1.17202652
70MP0002938_white_spotting1.16610488
71MP0001919_abnormal_reproductive_system1.16328181
72MP0008058_abnormal_DNA_repair1.15968100
73MP0001963_abnormal_hearing_physiology1.15422177
74MP0005389_reproductive_system_phenotype1.15421277
75MP0002160_abnormal_reproductive_system1.14315929
76MP0001485_abnormal_pinna_reflex1.14301630
77MP0004859_abnormal_synaptic_plasticity1.13683917
78MP0000015_abnormal_ear_pigmentation1.12830917
79MP0002928_abnormal_bile_duct1.12439938
80MP0000026_abnormal_inner_ear1.10217837
81MP0005195_abnormal_posterior_eye1.04222124
82MP0003890_abnormal_embryonic-extraembry1.02288265
83MP0001293_anophthalmia1.01995179
84MP0000920_abnormal_myelination1.01615937
85MP0002102_abnormal_ear_morphology1.01372335
86MP0008789_abnormal_olfactory_epithelium1.01229055
87MP0005084_abnormal_gallbladder_morpholo1.00828741
88MP0001502_abnormal_circadian_rhythm1.00677677
89MP0004145_abnormal_muscle_electrophysio0.99176329
90MP0005408_hypopigmentation0.98917010
91MP0003119_abnormal_digestive_system0.97344512
92MP0002229_neurodegeneration0.97003892
93MP0003137_abnormal_impulse_conducting0.96383676
94MP0000427_abnormal_hair_cycle0.96269529
95MP0002277_abnormal_respiratory_mucosa0.95889931
96MP0003186_abnormal_redox_activity0.94018018
97MP0005332_abnormal_amino_acid0.93722383
98MP0002752_abnormal_somatic_nervous0.92588678
99MP0004147_increased_porphyrin_level0.91695783
100MP0005253_abnormal_eye_physiology0.90894324
101MP0005499_abnormal_olfactory_system0.88986289
102MP0005394_taste/olfaction_phenotype0.88986289
103MP0000049_abnormal_middle_ear0.88031625
104MP0002066_abnormal_motor_capabilities/c0.88012470
105MP0005410_abnormal_fertilization0.87945955
106MP0001324_abnormal_eye_pigmentation0.87940997
107MP0008872_abnormal_physiological_respon0.87768545
108MP0005535_abnormal_body_temperature0.87672999
109MP0010030_abnormal_orbit_morphology0.87038163
110MP0002882_abnormal_neuron_morphology0.86822121
111MP0005391_vision/eye_phenotype0.85182369
112MP0002751_abnormal_autonomic_nervous0.84069916
113MP0003937_abnormal_limbs/digits/tail_de0.83879145
114MP0003698_abnormal_male_reproductive0.83384610
115MP0003879_abnormal_hair_cell0.80705894
116MP0004381_abnormal_hair_follicle0.79468746
117MP0005075_abnormal_melanosome_morpholog0.77672096
118MP0005174_abnormal_tail_pigmentation0.76431097
119MP0004036_abnormal_muscle_relaxation0.75680947
120MP0008004_abnormal_stomach_pH0.73450652
121MP0001664_abnormal_digestion0.72801185
122MP0001727_abnormal_embryo_implantation0.71610405
123MP0000538_abnormal_urinary_bladder0.70979852
124MP0000749_muscle_degeneration0.70841950
125MP0002090_abnormal_vision0.69928788
126MP0001764_abnormal_homeostasis0.69876355
127MP0003195_calcinosis0.69267564
128MP0004043_abnormal_pH_regulation0.68485246
129MP0003718_maternal_effect0.67172227
130MP0001542_abnormal_bone_strength0.65624224
131MP0004215_abnormal_myocardial_fiber0.64327943
132MP0003634_abnormal_glial_cell0.63275568

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.60190427
2Abnormal mitochondria in muscle tissue (HP:0008316)5.88418796
3Mitochondrial inheritance (HP:0001427)5.74591295
4Progressive macrocephaly (HP:0004481)5.50468502
5Acute encephalopathy (HP:0006846)5.37024035
6Hepatocellular necrosis (HP:0001404)4.80683605
7Increased CSF lactate (HP:0002490)4.79592602
8Increased hepatocellular lipid droplets (HP:0006565)4.67219473
9Renal Fanconi syndrome (HP:0001994)4.27283082
10Lipid accumulation in hepatocytes (HP:0006561)4.09059050
11Hepatic necrosis (HP:0002605)4.05968862
123-Methylglutaconic aciduria (HP:0003535)3.92418431
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.78043548
14Hypothermia (HP:0002045)3.75309421
15Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.65754865
16Optic disc pallor (HP:0000543)3.63668973
17Cerebral edema (HP:0002181)3.58235030
18Exercise intolerance (HP:0003546)3.37362776
19Increased intramyocellular lipid droplets (HP:0012240)3.34403787
20Increased serum pyruvate (HP:0003542)3.31446602
21Abnormality of glycolysis (HP:0004366)3.31446602
22Lactic acidosis (HP:0003128)3.27707258
23Medial flaring of the eyebrow (HP:0010747)3.18659188
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.17398414
25Decreased activity of mitochondrial respiratory chain (HP:0008972)3.17398414
26Leukodystrophy (HP:0002415)3.15573734
27Respiratory failure (HP:0002878)3.15455240
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.06765350
29Abnormality of renal resorption (HP:0011038)3.01736389
30Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.99523913
31Abnormal ciliary motility (HP:0012262)2.99177900
32Exertional dyspnea (HP:0002875)2.98833101
33Increased serum lactate (HP:0002151)2.96185039
34Abnormality of the renal medulla (HP:0100957)2.89611361
35Focal motor seizures (HP:0011153)2.87306031
36Abnormality of the renal cortex (HP:0011035)2.85255135
37Abnormal respiratory motile cilium physiology (HP:0012261)2.82769814
38Gait imbalance (HP:0002141)2.76424252
39Abnormal respiratory motile cilium morphology (HP:0005938)2.74165688
40Abnormal respiratory epithelium morphology (HP:0012253)2.74165688
41Increased muscle lipid content (HP:0009058)2.71538045
42Congenital primary aphakia (HP:0007707)2.70699649
43Congenital stationary night blindness (HP:0007642)2.59461100
44True hermaphroditism (HP:0010459)2.59005904
45Dynein arm defect of respiratory motile cilia (HP:0012255)2.58856978
46Absent/shortened dynein arms (HP:0200106)2.58856978
47Nephrogenic diabetes insipidus (HP:0009806)2.58441813
48Respiratory difficulties (HP:0002880)2.56391104
49Type II lissencephaly (HP:0007260)2.56020069
50Pancreatic fibrosis (HP:0100732)2.46264482
51Congenital, generalized hypertrichosis (HP:0004540)2.45710770
52Parakeratosis (HP:0001036)2.43599632
53Neuroendocrine neoplasm (HP:0100634)2.39153017
54Sclerocornea (HP:0000647)2.38900980
55Rhinitis (HP:0012384)2.29222288
56X-linked dominant inheritance (HP:0001423)2.27944353
57Genital tract atresia (HP:0001827)2.26695756
58Tubular atrophy (HP:0000092)2.26628795
59Vaginal atresia (HP:0000148)2.24434214
60Renal cortical cysts (HP:0000803)2.24071106
61Chronic hepatic failure (HP:0100626)2.23097819
62Cystic liver disease (HP:0006706)2.22821547
63Atonic seizures (HP:0010819)2.22358336
64Retinal dysplasia (HP:0007973)2.21525682
65Abnormality of the labia minora (HP:0012880)2.20598554
66Abnormal biliary tract physiology (HP:0012439)2.20560860
67Bile duct proliferation (HP:0001408)2.20560860
68Abnormal hair whorl (HP:0010721)2.19728257
69Hyperglycinemia (HP:0002154)2.17461958
70Microvesicular hepatic steatosis (HP:0001414)2.15998995
71Tubulointerstitial nephritis (HP:0001970)2.15701680
72Pheochromocytoma (HP:0002666)2.13367789
73Attenuation of retinal blood vessels (HP:0007843)2.12333214
74Polydipsia (HP:0001959)2.12163579
75Abnormal drinking behavior (HP:0030082)2.12163579
76Abnormality of cells of the erythroid lineage (HP:0012130)2.11428283
77Abnormal pupillary function (HP:0007686)2.10828849
78Abnormality of midbrain morphology (HP:0002418)2.09213598
79Molar tooth sign on MRI (HP:0002419)2.09213598
80Furrowed tongue (HP:0000221)2.08474196
81Epileptic encephalopathy (HP:0200134)2.04365936
82Abolished electroretinogram (ERG) (HP:0000550)2.03991496
83Aplasia/Hypoplasia of the tongue (HP:0010295)2.03794738
84Limb dystonia (HP:0002451)2.03589622
85Anencephaly (HP:0002323)2.03306189
86Hyperalaninemia (HP:0003348)2.03282017
87Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03282017
88Abnormality of alanine metabolism (HP:0010916)2.03282017
89Intestinal atresia (HP:0011100)2.01146828
90Hyperphosphaturia (HP:0003109)1.99902757
91Methylmalonic acidemia (HP:0002912)1.98797938
92Lissencephaly (HP:0001339)1.98407490
93Myokymia (HP:0002411)1.98126917
94Hyperventilation (HP:0002883)1.96753528
95Abnormal number of erythroid precursors (HP:0012131)1.94660477
96Renal tubular dysfunction (HP:0000124)1.93241053
97Glycosuria (HP:0003076)1.92232855
98Abnormality of urine glucose concentration (HP:0011016)1.92232855
99Abnormal rod and cone electroretinograms (HP:0008323)1.89108654
100Congenital hepatic fibrosis (HP:0002612)1.87789627
101Pendular nystagmus (HP:0012043)1.86846184
102Sensory axonal neuropathy (HP:0003390)1.86573041
103Optic nerve hypoplasia (HP:0000609)1.86561097
104Pancreatic cysts (HP:0001737)1.86511635
105Type I transferrin isoform profile (HP:0003642)1.85880860
106CNS demyelination (HP:0007305)1.84139829
107Inability to walk (HP:0002540)1.83638674
108Polyuria (HP:0000103)1.83597284
109Pachygyria (HP:0001302)1.83254395
110Cerebellar dysplasia (HP:0007033)1.81786316
111Concave nail (HP:0001598)1.79436787
112Poor coordination (HP:0002370)1.79082692
113Congenital ichthyosiform erythroderma (HP:0007431)1.79048282
114Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.78483485
115Emotional lability (HP:0000712)1.78385279
116Methylmalonic aciduria (HP:0012120)1.76414693
117Lethargy (HP:0001254)1.76120677
118Increased corneal curvature (HP:0100692)1.75935165
119Keratoconus (HP:0000563)1.75935165
120Large for gestational age (HP:0001520)1.75398743
121Polyphagia (HP:0002591)1.75137875
122Degeneration of the lateral corticospinal tracts (HP:0002314)1.73997093
123Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.73997093
124Occipital encephalocele (HP:0002085)1.73237111
125Hyperglycinuria (HP:0003108)1.73034697
126Aplasia/Hypoplasia of the lens (HP:0008063)1.72257735
127Abnormality of secondary sexual hair (HP:0009888)1.71609886
128Abnormality of the axillary hair (HP:0100134)1.71609886
129Esotropia (HP:0000565)1.69408152
130Poor suck (HP:0002033)1.68553058
131Absence seizures (HP:0002121)1.67858450
132Febrile seizures (HP:0002373)1.66340954
133Aplasia/hypoplasia of the uterus (HP:0008684)1.65664065
134Blindness (HP:0000618)1.65554582
135Male pseudohermaphroditism (HP:0000037)1.65115538
136Aplasia/Hypoplasia of the tibia (HP:0005772)1.64381533
137Nephronophthisis (HP:0000090)1.63545505
138Dialeptic seizures (HP:0011146)1.62239244
139Abnormal urine phosphate concentration (HP:0012599)1.61479736

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK3.93040304
2MAP3K123.38174954
3STK163.33495908
4CASK3.29616902
5NME12.84137529
6ARAF2.76293598
7MAP4K22.73482737
8GRK72.46607604
9MST42.39671840
10TNIK2.37974866
11BMPR22.32367619
12MUSK2.26657526
13MAP2K72.20545714
14STK392.14530756
15BMPR1B1.96489705
16PBK1.90721818
17NUAK11.80234641
18PNCK1.80079692
19ACVR1B1.79757681
20ADRBK21.76802836
21OXSR11.76112992
22GRK51.75442149
23VRK21.70395029
24CDK191.68335266
25VRK11.66627038
26TRIM281.65630117
27MYLK1.63325012
28BCR1.53805696
29EPHA41.41104813
30CAMKK21.39309802
31MAPK131.36605333
32WNK41.35718328
33NME21.34525301
34NTRK31.31510345
35MAPK151.29443531
36PLK21.29428849
37BRAF1.28329491
38TGFBR11.26962421
39MAPKAPK51.25474771
40TAOK31.23567772
41PIM21.22539205
42PHKG21.18230909
43PHKG11.18230909
44RIPK41.14217740
45TAF11.11096712
46MAP3K41.06559547
47PAK31.06501767
48TIE11.02856305
49OBSCN1.02419123
50CAMK2A1.02334039
51IRAK41.01100615
52CAMK2B1.00026359
53DYRK20.99741315
54DAPK20.98751316
55FGFR20.96746185
56PLK30.94682503
57CSNK1G30.94534075
58SIK30.92607079
59INSRR0.90575454
60LIMK10.90420833
61CDK80.88337854
62CAMK2D0.86377984
63PRKCE0.83859169
64PLK40.80780036
65MARK10.79142498
66WNK30.78896657
67IRAK10.78469879
68TEC0.76675025
69PRPF4B0.75508193
70ERBB30.74907823
71RPS6KA50.74512301
72CAMK2G0.74413530
73NEK60.74287414
74PINK10.73279718
75ADRBK10.73017932
76PKN10.70738360
77AKT30.70279048
78GRK10.69974541
79UHMK10.68927844
80EIF2AK30.68684624
81PRKCG0.66624011
82BRSK20.66174161
83TXK0.65729033
84CDK30.65022508
85MINK10.63549165
86YES10.63273242
87DYRK30.62505300
88BLK0.61694863
89PTK2B0.61539101
90PASK0.61235283
91STK240.60950760
92CSNK1G20.60268393
93MOS0.59663122
94CSNK1G10.59651940
95FGR0.57798839
96EPHA30.57539342
97BUB10.57249897
98STK38L0.56882226
99PRKACA0.56205597
100ZAK0.55493633
101PIK3CA0.55485961
102ABL20.54570978
103TNK20.53530558
104EIF2AK10.53406177
105PIK3CG0.53017874
106MAP2K40.51809269
107CCNB10.50099275
108IRAK20.49826643
109PLK10.49183789
110DYRK1A0.48544056
111IRAK30.47848556
112TLK10.46647416
113SRPK10.46560433
114CDK50.45638736
115MKNK10.45303117
116MAP2K60.44788554
117BCKDK0.44059269
118CDC70.43146455
119CSNK1A10.42993621
120PRKCI0.42991327
121DAPK10.42773046
122NTRK20.42629096
123CHEK20.41295578
124MAP3K90.41208524
125FLT30.40949308
126PRKCQ0.40643822
127ROCK20.40407713
128PRKG10.39499961
129WEE10.39423370
130MKNK20.38590145
131FES0.38467598
132SYK0.37882190
133CSNK1A1L0.36361700
134MAP3K140.35752965
135CAMK10.34427193
136TSSK60.34036328
137CSNK1D0.33056557
138ATR0.32368018
139CSNK2A10.32148690
140PRKCA0.30895913
141PRKACB0.30829037

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001906.18418858
2Parkinsons disease_Homo sapiens_hsa050125.10399912
3Alzheimers disease_Homo sapiens_hsa050103.99337163
4Huntingtons disease_Homo sapiens_hsa050163.69133459
5Protein export_Homo sapiens_hsa030603.49394454
6Proteasome_Homo sapiens_hsa030503.14038059
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.08655073
8Ribosome_Homo sapiens_hsa030102.96716059
9Collecting duct acid secretion_Homo sapiens_hsa049662.42631809
10Cardiac muscle contraction_Homo sapiens_hsa042602.33621638
11RNA polymerase_Homo sapiens_hsa030202.19347101
12Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.85282315
13Nicotine addiction_Homo sapiens_hsa050331.82339071
14Fatty acid elongation_Homo sapiens_hsa000621.67777224
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.67348276
16Selenocompound metabolism_Homo sapiens_hsa004501.64986006
17Vibrio cholerae infection_Homo sapiens_hsa051101.63024326
18Nitrogen metabolism_Homo sapiens_hsa009101.56537649
19Fanconi anemia pathway_Homo sapiens_hsa034601.55122766
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.49905401
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.49073206
22Serotonergic synapse_Homo sapiens_hsa047261.43652737
23Sulfur metabolism_Homo sapiens_hsa009201.39376986
24Tryptophan metabolism_Homo sapiens_hsa003801.37364251
25Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.33186853
26Caffeine metabolism_Homo sapiens_hsa002321.31788663
27Synaptic vesicle cycle_Homo sapiens_hsa047211.28808738
28Phototransduction_Homo sapiens_hsa047441.25222124
29Rheumatoid arthritis_Homo sapiens_hsa053231.25221533
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23367065
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19642948
32Taste transduction_Homo sapiens_hsa047421.11865517
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.11589082
34GABAergic synapse_Homo sapiens_hsa047271.06631698
35Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.05256234
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.01542976
37Pyrimidine metabolism_Homo sapiens_hsa002401.00160266
38Morphine addiction_Homo sapiens_hsa050320.99841402
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.97508720
40Primary bile acid biosynthesis_Homo sapiens_hsa001200.93292492
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93264597
42Steroid biosynthesis_Homo sapiens_hsa001000.92032022
43Ether lipid metabolism_Homo sapiens_hsa005650.89705575
44Purine metabolism_Homo sapiens_hsa002300.88915856
45Circadian entrainment_Homo sapiens_hsa047130.86896295
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86065966
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.85364923
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84561467
49Glutamatergic synapse_Homo sapiens_hsa047240.84266141
50One carbon pool by folate_Homo sapiens_hsa006700.84161483
51Amphetamine addiction_Homo sapiens_hsa050310.83114533
52Metabolic pathways_Homo sapiens_hsa011000.82887799
53Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80172813
54Pyruvate metabolism_Homo sapiens_hsa006200.79360016
55Olfactory transduction_Homo sapiens_hsa047400.79326391
56beta-Alanine metabolism_Homo sapiens_hsa004100.77137189
57Retinol metabolism_Homo sapiens_hsa008300.76728388
58Basal transcription factors_Homo sapiens_hsa030220.74746420
59Dopaminergic synapse_Homo sapiens_hsa047280.74079854
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73847925
61Arachidonic acid metabolism_Homo sapiens_hsa005900.70801626
62Tyrosine metabolism_Homo sapiens_hsa003500.69352937
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68948550
64Phagosome_Homo sapiens_hsa041450.68232413
65Sphingolipid metabolism_Homo sapiens_hsa006000.64806256
66Long-term depression_Homo sapiens_hsa047300.64209549
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.63223456
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63046122
69Mismatch repair_Homo sapiens_hsa034300.62198133
70Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61648458
71Regulation of autophagy_Homo sapiens_hsa041400.59447924
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.57928264
73Calcium signaling pathway_Homo sapiens_hsa040200.57481147
74Fatty acid degradation_Homo sapiens_hsa000710.56693018
75Propanoate metabolism_Homo sapiens_hsa006400.56578595
76Cocaine addiction_Homo sapiens_hsa050300.56399025
77ABC transporters_Homo sapiens_hsa020100.56153805
78Glutathione metabolism_Homo sapiens_hsa004800.55755889
79Histidine metabolism_Homo sapiens_hsa003400.55426244
80Renin secretion_Homo sapiens_hsa049240.54783417
81Peroxisome_Homo sapiens_hsa041460.52566026
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52520332
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51304385
84RNA degradation_Homo sapiens_hsa030180.50209195
85RNA transport_Homo sapiens_hsa030130.49793923
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49505641
87Phenylalanine metabolism_Homo sapiens_hsa003600.48766287
88Fat digestion and absorption_Homo sapiens_hsa049750.48412501
89Fatty acid metabolism_Homo sapiens_hsa012120.48010093
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47874197
91Salivary secretion_Homo sapiens_hsa049700.47750133
92Base excision repair_Homo sapiens_hsa034100.47252660
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.46530580
94Cholinergic synapse_Homo sapiens_hsa047250.46334643
95Chemical carcinogenesis_Homo sapiens_hsa052040.45907004
96Homologous recombination_Homo sapiens_hsa034400.45665169
97Insulin secretion_Homo sapiens_hsa049110.43338556
98Long-term potentiation_Homo sapiens_hsa047200.42836827
99Linoleic acid metabolism_Homo sapiens_hsa005910.42173720
100Nucleotide excision repair_Homo sapiens_hsa034200.41574192
101Mineral absorption_Homo sapiens_hsa049780.40170150
102Circadian rhythm_Homo sapiens_hsa047100.40075121
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39348853
104Autoimmune thyroid disease_Homo sapiens_hsa053200.38652549
105Hedgehog signaling pathway_Homo sapiens_hsa043400.38556036
106Intestinal immune network for IgA production_Homo sapiens_hsa046720.38055295
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.36687168
108Basal cell carcinoma_Homo sapiens_hsa052170.35336808
109Non-homologous end-joining_Homo sapiens_hsa034500.34612358
110Folate biosynthesis_Homo sapiens_hsa007900.34478492
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.30622865
112Graft-versus-host disease_Homo sapiens_hsa053320.30269442
113Butanoate metabolism_Homo sapiens_hsa006500.30243107
114Arginine and proline metabolism_Homo sapiens_hsa003300.28401495
115African trypanosomiasis_Homo sapiens_hsa051430.28313142
116Maturity onset diabetes of the young_Homo sapiens_hsa049500.25801213
117Alcoholism_Homo sapiens_hsa050340.24729868
118Allograft rejection_Homo sapiens_hsa053300.24489851
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.23609897
120Asthma_Homo sapiens_hsa053100.23281622
121Spliceosome_Homo sapiens_hsa030400.23220405
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.22927251
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.22327503
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21441006
125Type I diabetes mellitus_Homo sapiens_hsa049400.20619915
126Oxytocin signaling pathway_Homo sapiens_hsa049210.18286638
127alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.17286790
128Steroid hormone biosynthesis_Homo sapiens_hsa001400.15217195
129Gastric acid secretion_Homo sapiens_hsa049710.15053982
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.14384709
131Ovarian steroidogenesis_Homo sapiens_hsa049130.14032010
132Pentose and glucuronate interconversions_Homo sapiens_hsa000400.12318656

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