

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 9.55251147 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.45751509 |
| 3 | cytidine deamination (GO:0009972) | 7.04987703 |
| 4 | cytidine metabolic process (GO:0046087) | 7.04987703 |
| 5 | cytidine catabolic process (GO:0006216) | 7.04987703 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.08437577 |
| 7 | rRNA methylation (GO:0031167) | 5.97646707 |
| 8 | rRNA modification (GO:0000154) | 5.82168286 |
| 9 | protein deneddylation (GO:0000338) | 4.93890774 |
| 10 | cullin deneddylation (GO:0010388) | 4.87080962 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.16470019 |
| 12 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.15405214 |
| 13 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.05284890 |
| 14 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.05284890 |
| 15 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.02483978 |
| 16 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.02483978 |
| 17 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.02483978 |
| 18 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.98813789 |
| 19 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.97009494 |
| 20 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.96907932 |
| 21 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.96907932 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.96748843 |
| 23 | cellular response to interleukin-15 (GO:0071350) | 3.95883384 |
| 24 | regulation of translational termination (GO:0006449) | 3.91405204 |
| 25 | mitochondrion distribution (GO:0048311) | 3.90712475 |
| 26 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.86913989 |
| 27 | proteasome assembly (GO:0043248) | 3.84980242 |
| 28 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.81395997 |
| 29 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.81395997 |
| 30 | positive regulation of defense response to virus by host (GO:0002230) | 3.78550490 |
| 31 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.77560025 |
| 32 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.73208059 |
| 33 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.68301492 |
| 34 | negative regulation of ligase activity (GO:0051352) | 3.68301492 |
| 35 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.67340881 |
| 36 | positive regulation of prostaglandin secretion (GO:0032308) | 3.57365830 |
| 37 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 3.52370214 |
| 38 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.45460547 |
| 39 | signal peptide processing (GO:0006465) | 3.44670975 |
| 40 | organelle disassembly (GO:1903008) | 3.29470677 |
| 41 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.29265827 |
| 42 | ribonucleoprotein complex disassembly (GO:0032988) | 3.25325480 |
| 43 | response to interleukin-15 (GO:0070672) | 3.24976530 |
| 44 | regulation of prostaglandin secretion (GO:0032306) | 3.22437782 |
| 45 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.19387343 |
| 46 | protein K6-linked ubiquitination (GO:0085020) | 3.19147209 |
| 47 | positive regulation of cell cycle arrest (GO:0071158) | 3.16867360 |
| 48 | positive regulation of ligase activity (GO:0051351) | 3.14932820 |
| 49 | regulation of interleukin-8 secretion (GO:2000482) | 3.14926747 |
| 50 | termination of RNA polymerase III transcription (GO:0006386) | 3.10903019 |
| 51 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.10903019 |
| 52 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.10465333 |
| 53 | peptidyl-histidine modification (GO:0018202) | 3.09620926 |
| 54 | cytochrome complex assembly (GO:0017004) | 3.04899270 |
| 55 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.00570018 |
| 56 | T cell apoptotic process (GO:0070231) | 2.99416091 |
| 57 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.98845360 |
| 58 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.98683320 |
| 59 | protein heterotetramerization (GO:0051290) | 2.97841739 |
| 60 | ATP synthesis coupled proton transport (GO:0015986) | 2.97042221 |
| 61 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.97042221 |
| 62 | regulation of mitochondrial translation (GO:0070129) | 2.95558487 |
| 63 | ER overload response (GO:0006983) | 2.94415640 |
| 64 | respiratory chain complex IV assembly (GO:0008535) | 2.91853930 |
| 65 | DNA demethylation (GO:0080111) | 2.91033682 |
| 66 | regulation of defense response to virus by host (GO:0050691) | 2.89598457 |
| 67 | negative regulation of B cell apoptotic process (GO:0002903) | 2.89093349 |
| 68 | ribosomal small subunit assembly (GO:0000028) | 2.85710589 |
| 69 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.85519517 |
| 70 | eosinophil chemotaxis (GO:0048245) | 2.81713991 |
| 71 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.81060324 |
| 72 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.79252796 |
| 73 | lymphocyte apoptotic process (GO:0070227) | 2.75190506 |
| 74 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.75061210 |
| 75 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.75004230 |
| 76 | AMP metabolic process (GO:0046033) | 2.74327943 |
| 77 | DNA double-strand break processing (GO:0000729) | 2.73968542 |
| 78 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.72250476 |
| 79 | negative regulation of macroautophagy (GO:0016242) | 2.71796164 |
| 80 | regulation of ligase activity (GO:0051340) | 2.69400100 |
| 81 | regulation of cellular amine metabolic process (GO:0033238) | 2.68607194 |
| 82 | T cell migration (GO:0072678) | 2.66822212 |
| 83 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.65834912 |
| 84 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.64072893 |
| 85 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.63324791 |
| 86 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.63324791 |
| 87 | mismatch repair (GO:0006298) | 2.63207226 |
| 88 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.62990018 |
| 89 | pseudouridine synthesis (GO:0001522) | 2.61085581 |
| 90 | amino acid activation (GO:0043038) | 2.59012917 |
| 91 | tRNA aminoacylation (GO:0043039) | 2.59012917 |
| 92 | chaperone-mediated protein transport (GO:0072321) | 2.57440821 |
| 93 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.56616357 |
| 94 | protein complex biogenesis (GO:0070271) | 2.56159190 |
| 95 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.55558005 |
| 96 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.55354014 |
| 97 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.55216214 |
| 98 | regulation of vacuole organization (GO:0044088) | 2.55047892 |
| 99 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.52228769 |
| 100 | respiratory electron transport chain (GO:0022904) | 2.50634481 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.70586163 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.74155736 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.64777562 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.43201614 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.87924940 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.65663000 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.41151867 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 3.14448595 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.83965318 |
| 10 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.73980256 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.69676045 |
| 12 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.68727373 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61057815 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.55871346 |
| 15 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.53119576 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50964852 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.39161301 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.29802227 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.27199297 |
| 20 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.19106963 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.16628887 |
| 22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.14759699 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.06476500 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.00040662 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.97645705 |
| 26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.93977031 |
| 27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.87228432 |
| 28 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.86184004 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.83467711 |
| 30 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.79676043 |
| 31 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.78873046 |
| 32 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.75178346 |
| 33 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.69937735 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.67618913 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.67534859 |
| 36 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.57059734 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.54975452 |
| 38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.48144876 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.46555983 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.45490882 |
| 41 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.42296469 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.39340768 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38944434 |
| 44 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33172477 |
| 45 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.30713244 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.30124019 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.29466347 |
| 48 | MYB_26560356_Chip-Seq_TH2_Human | 1.27975654 |
| 49 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.22921101 |
| 50 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.21415377 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.19977821 |
| 52 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.17733268 |
| 53 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.17733268 |
| 54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.13492310 |
| 55 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.11096386 |
| 56 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.10742444 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.08065770 |
| 58 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.07062730 |
| 59 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.06199437 |
| 60 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05522530 |
| 61 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05399309 |
| 62 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.03800061 |
| 63 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.02800621 |
| 64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.99834384 |
| 65 | MYB_26560356_Chip-Seq_TH1_Human | 0.99362204 |
| 66 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.98850802 |
| 67 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.98247713 |
| 68 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.95096299 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.94113470 |
| 70 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.93910115 |
| 71 | P300_19829295_ChIP-Seq_ESCs_Human | 0.93026006 |
| 72 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92074403 |
| 73 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89722322 |
| 74 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.89469145 |
| 75 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89257486 |
| 76 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.88660590 |
| 77 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88656740 |
| 78 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.87879564 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.87721528 |
| 80 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87487543 |
| 81 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.87414469 |
| 82 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.84340022 |
| 83 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.83924667 |
| 84 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.83924667 |
| 85 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.83634538 |
| 86 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.83421599 |
| 87 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.83363155 |
| 88 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.83030113 |
| 89 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.82893459 |
| 90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82122614 |
| 91 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.80901607 |
| 92 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.78504690 |
| 93 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.76701575 |
| 94 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.76635648 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.76559891 |
| 96 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.76546620 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.76333809 |
| 98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.75841944 |
| 99 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.74511984 |
| 100 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.74401786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009333_abnormal_splenocyte_physiolog | 3.92141195 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.64932849 |
| 3 | MP0002102_abnormal_ear_morphology | 3.43717566 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 3.39404053 |
| 5 | MP0005671_abnormal_response_to | 3.36966226 |
| 6 | MP0000685_abnormal_immune_system | 2.78422060 |
| 7 | MP0003045_fibrosis | 2.73618777 |
| 8 | MP0005083_abnormal_biliary_tract | 2.67498707 |
| 9 | MP0002166_altered_tumor_susceptibility | 2.63199399 |
| 10 | MP0002876_abnormal_thyroid_physiology | 2.60207659 |
| 11 | MP0009785_altered_susceptibility_to | 2.58236676 |
| 12 | MP0002148_abnormal_hypersensitivity_rea | 2.56299108 |
| 13 | MP0002006_tumorigenesis | 2.52949037 |
| 14 | MP0001835_abnormal_antigen_presentation | 2.48614688 |
| 15 | MP0004957_abnormal_blastocyst_morpholog | 2.17678979 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 2.15562699 |
| 17 | MP0003786_premature_aging | 2.13283687 |
| 18 | MP0005408_hypopigmentation | 2.11970485 |
| 19 | MP0010386_abnormal_urinary_bladder | 2.11949085 |
| 20 | MP0005360_urolithiasis | 2.05724272 |
| 21 | MP0005000_abnormal_immune_tolerance | 2.02145322 |
| 22 | MP0000747_muscle_weakness | 1.97420278 |
| 23 | MP0001800_abnormal_humoral_immune | 1.95090796 |
| 24 | MP0006035_abnormal_mitochondrial_morpho | 1.94068837 |
| 25 | MP0001790_abnormal_immune_system | 1.90525481 |
| 26 | MP0005387_immune_system_phenotype | 1.90525481 |
| 27 | MP0006036_abnormal_mitochondrial_physio | 1.89246500 |
| 28 | MP0008058_abnormal_DNA_repair | 1.78166924 |
| 29 | MP0003866_abnormal_defecation | 1.73329138 |
| 30 | MP0010094_abnormal_chromosome_stability | 1.73115753 |
| 31 | MP0002723_abnormal_immune_serum | 1.63539621 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 1.62277557 |
| 33 | MP0002420_abnormal_adaptive_immunity | 1.58778435 |
| 34 | MP0001819_abnormal_immune_cell | 1.53805214 |
| 35 | MP0005165_increased_susceptibility_to | 1.48053998 |
| 36 | MP0006082_CNS_inflammation | 1.47757800 |
| 37 | MP0003252_abnormal_bile_duct | 1.43061105 |
| 38 | MP0003693_abnormal_embryo_hatching | 1.41727917 |
| 39 | MP0008057_abnormal_DNA_replication | 1.40470995 |
| 40 | MP0005025_abnormal_response_to | 1.40158428 |
| 41 | MP0002452_abnormal_antigen_presenting | 1.37737169 |
| 42 | MP0002163_abnormal_gland_morphology | 1.34229867 |
| 43 | MP0001873_stomach_inflammation | 1.33245290 |
| 44 | MP0002398_abnormal_bone_marrow | 1.30346444 |
| 45 | MP0000751_myopathy | 1.30297436 |
| 46 | MP0008877_abnormal_DNA_methylation | 1.27581364 |
| 47 | MP0000703_abnormal_thymus_morphology | 1.26702619 |
| 48 | MP0003195_calcinosis | 1.26338136 |
| 49 | MP0000716_abnormal_immune_system | 1.24958424 |
| 50 | MP0004134_abnormal_chest_morphology | 1.22015944 |
| 51 | MP0002095_abnormal_skin_pigmentation | 1.20969718 |
| 52 | MP0003646_muscle_fatigue | 1.18288066 |
| 53 | MP0008007_abnormal_cellular_replicative | 1.16968615 |
| 54 | MP0002396_abnormal_hematopoietic_system | 1.13452535 |
| 55 | MP0002722_abnormal_immune_system | 1.12142521 |
| 56 | MP0003763_abnormal_thymus_physiology | 1.11382580 |
| 57 | MP0003077_abnormal_cell_cycle | 1.11049820 |
| 58 | MP0000689_abnormal_spleen_morphology | 1.08328363 |
| 59 | MP0003283_abnormal_digestive_organ | 1.08211189 |
| 60 | MP0000372_irregular_coat_pigmentation | 1.03770773 |
| 61 | MP0001845_abnormal_inflammatory_respons | 1.03212811 |
| 62 | MP0002429_abnormal_blood_cell | 1.03114018 |
| 63 | MP0001348_abnormal_lacrimal_gland | 1.01842176 |
| 64 | MP0004885_abnormal_endolymph | 1.00940936 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 0.99337897 |
| 66 | MP0005085_abnormal_gallbladder_physiolo | 0.97471299 |
| 67 | MP0000749_muscle_degeneration | 0.97374990 |
| 68 | MP0003111_abnormal_nucleus_morphology | 0.95508892 |
| 69 | MP0002419_abnormal_innate_immunity | 0.94528912 |
| 70 | MP0003448_altered_tumor_morphology | 0.92900627 |
| 71 | MP0005410_abnormal_fertilization | 0.92885501 |
| 72 | MP0002693_abnormal_pancreas_physiology | 0.92145063 |
| 73 | MP0001661_extended_life_span | 0.92130120 |
| 74 | MP0006072_abnormal_retinal_apoptosis | 0.89484774 |
| 75 | MP0003718_maternal_effect | 0.89337339 |
| 76 | MP0002736_abnormal_nociception_after | 0.88202168 |
| 77 | MP0001968_abnormal_touch/_nociception | 0.87865992 |
| 78 | MP0001905_abnormal_dopamine_level | 0.84563267 |
| 79 | MP0008872_abnormal_physiological_respon | 0.79895976 |
| 80 | MP0005365_abnormal_bile_salt | 0.79205231 |
| 81 | MP0004510_myositis | 0.78426779 |
| 82 | MP0010155_abnormal_intestine_physiology | 0.78125091 |
| 83 | MP0004147_increased_porphyrin_level | 0.77513987 |
| 84 | MP0001765_abnormal_ion_homeostasis | 0.76769187 |
| 85 | MP0000358_abnormal_cell_content/ | 0.76453884 |
| 86 | MP0002405_respiratory_system_inflammati | 0.74205601 |
| 87 | MP0001756_abnormal_urination | 0.74130402 |
| 88 | MP0000681_abnormal_thyroid_gland | 0.73708156 |
| 89 | MP0002269_muscular_atrophy | 0.70978436 |
| 90 | MP0000569_abnormal_digit_pigmentation | 0.70744113 |
| 91 | MP0003950_abnormal_plasma_membrane | 0.70540375 |
| 92 | MP0002019_abnormal_tumor_incidence | 0.69669952 |
| 93 | MP0005464_abnormal_platelet_physiology | 0.68744968 |
| 94 | MP0004947_skin_inflammation | 0.68494294 |
| 95 | MP0005310_abnormal_salivary_gland | 0.67647228 |
| 96 | MP0004036_abnormal_muscle_relaxation | 0.67408452 |
| 97 | MP0009765_abnormal_xenobiotic_induced | 0.67313762 |
| 98 | MP0005395_other_phenotype | 0.64672890 |
| 99 | MP0001853_heart_inflammation | 0.64563653 |
| 100 | MP0005084_abnormal_gallbladder_morpholo | 0.64169757 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Neonatal respiratory distress (HP:0002643) | 4.64580384 |
| 2 | Febrile seizures (HP:0002373) | 4.42661311 |
| 3 | Colon cancer (HP:0003003) | 4.41827008 |
| 4 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.25641107 |
| 5 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.25641107 |
| 6 | Optic neuritis (HP:0100653) | 3.89243182 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 3.89243182 |
| 8 | Hepatosplenomegaly (HP:0001433) | 3.83483309 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.80028847 |
| 10 | Orchitis (HP:0100796) | 3.70474219 |
| 11 | Myositis (HP:0100614) | 3.60140140 |
| 12 | Hypokinesia (HP:0002375) | 3.59976406 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.41364740 |
| 14 | Increased CSF lactate (HP:0002490) | 3.41197081 |
| 15 | Hepatic necrosis (HP:0002605) | 3.39770427 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.37609441 |
| 17 | Keratoconjunctivitis sicca (HP:0001097) | 3.30104679 |
| 18 | Hepatocellular necrosis (HP:0001404) | 3.29094501 |
| 19 | Conjunctival hamartoma (HP:0100780) | 3.26463787 |
| 20 | Acute encephalopathy (HP:0006846) | 3.24962658 |
| 21 | Progressive macrocephaly (HP:0004481) | 3.22751797 |
| 22 | Keratoconjunctivitis (HP:0001096) | 3.13339777 |
| 23 | Aplastic anemia (HP:0001915) | 3.02034273 |
| 24 | Cerebral edema (HP:0002181) | 2.95887633 |
| 25 | Metaphyseal dysplasia (HP:0100255) | 2.92543187 |
| 26 | Abnormality of T cell number (HP:0011839) | 2.84367106 |
| 27 | Palpitations (HP:0001962) | 2.83687178 |
| 28 | Joint swelling (HP:0001386) | 2.72060800 |
| 29 | IgA deficiency (HP:0002720) | 2.69579259 |
| 30 | Neoplasm of the adrenal gland (HP:0100631) | 2.69100678 |
| 31 | Increased serum lactate (HP:0002151) | 2.68733967 |
| 32 | Premature loss of primary teeth (HP:0006323) | 2.64303424 |
| 33 | Cerebral hemorrhage (HP:0001342) | 2.56074217 |
| 34 | Chronic diarrhea (HP:0002028) | 2.50632314 |
| 35 | Generalized aminoaciduria (HP:0002909) | 2.47205015 |
| 36 | Neuroendocrine neoplasm (HP:0100634) | 2.47012818 |
| 37 | T lymphocytopenia (HP:0005403) | 2.46853300 |
| 38 | Cavernous hemangioma (HP:0001048) | 2.45168671 |
| 39 | Prostate neoplasm (HP:0100787) | 2.42834628 |
| 40 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.42248514 |
| 41 | Tubulointerstitial fibrosis (HP:0005576) | 2.36364912 |
| 42 | Lactic acidosis (HP:0003128) | 2.36282843 |
| 43 | Increased density of long bones (HP:0006392) | 2.30453937 |
| 44 | IgM deficiency (HP:0002850) | 2.30100888 |
| 45 | Oral leukoplakia (HP:0002745) | 2.29305740 |
| 46 | Abnormal spermatogenesis (HP:0008669) | 2.25576250 |
| 47 | Respiratory failure (HP:0002878) | 2.24242256 |
| 48 | Conjugated hyperbilirubinemia (HP:0002908) | 2.24152062 |
| 49 | Pheochromocytoma (HP:0002666) | 2.23172693 |
| 50 | Neck muscle weakness (HP:0000467) | 2.22641634 |
| 51 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.21975663 |
| 52 | Exercise intolerance (HP:0003546) | 2.21721926 |
| 53 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.20975819 |
| 54 | Melanoma (HP:0002861) | 2.20873443 |
| 55 | Abnormality of the prostate (HP:0008775) | 2.20059593 |
| 56 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.17615384 |
| 57 | Lipid accumulation in hepatocytes (HP:0006561) | 2.14268158 |
| 58 | Abnormality of the renal cortex (HP:0011035) | 2.13436629 |
| 59 | Optic disc pallor (HP:0000543) | 2.09804395 |
| 60 | Autoimmune hemolytic anemia (HP:0001890) | 2.07927355 |
| 61 | Diminished movement (HP:0002374) | 2.07112829 |
| 62 | Abnormality of T cells (HP:0002843) | 2.04964609 |
| 63 | Abnormality of the labia minora (HP:0012880) | 2.02708103 |
| 64 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.01614671 |
| 65 | Renal cortical cysts (HP:0000803) | 1.99731031 |
| 66 | Hamartoma of the eye (HP:0010568) | 1.92921182 |
| 67 | Keratitis (HP:0000491) | 1.92432603 |
| 68 | Vacuolated lymphocytes (HP:0001922) | 1.92064037 |
| 69 | Facial diplegia (HP:0001349) | 1.89543665 |
| 70 | IgG deficiency (HP:0004315) | 1.87362869 |
| 71 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.86063190 |
| 72 | Arterial thrombosis (HP:0004420) | 1.83897761 |
| 73 | Gangrene (HP:0100758) | 1.83607141 |
| 74 | Dyschromatopsia (HP:0007641) | 1.83140958 |
| 75 | Poor speech (HP:0002465) | 1.81012270 |
| 76 | Lethargy (HP:0001254) | 1.79227234 |
| 77 | Abnormality of methionine metabolism (HP:0010901) | 1.78095504 |
| 78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.77062718 |
| 79 | Hypoglycemic coma (HP:0001325) | 1.76640745 |
| 80 | Pulmonary infiltrates (HP:0002113) | 1.74294653 |
| 81 | Anorexia (HP:0002039) | 1.74291002 |
| 82 | Pancytopenia (HP:0001876) | 1.72959276 |
| 83 | Progressive microcephaly (HP:0000253) | 1.71119251 |
| 84 | Generalized tonic-clonic seizures (HP:0002069) | 1.71018822 |
| 85 | Increased hepatocellular lipid droplets (HP:0006565) | 1.70465884 |
| 86 | Abnormality of the anterior horn cell (HP:0006802) | 1.69992142 |
| 87 | Degeneration of anterior horn cells (HP:0002398) | 1.69992142 |
| 88 | Spinal cord lesions (HP:0100561) | 1.69907196 |
| 89 | Syringomyelia (HP:0003396) | 1.69907196 |
| 90 | Abnormality of dental color (HP:0011073) | 1.69196233 |
| 91 | Tetraparesis (HP:0002273) | 1.68900019 |
| 92 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.68842028 |
| 93 | Uterine neoplasm (HP:0010784) | 1.68567507 |
| 94 | Abnormality of the vocal cords (HP:0008777) | 1.67282773 |
| 95 | Periodontitis (HP:0000704) | 1.66785948 |
| 96 | Clubbing of toes (HP:0100760) | 1.65745809 |
| 97 | Vasculitis (HP:0002633) | 1.65590090 |
| 98 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.64977279 |
| 99 | Goiter (HP:0000853) | 1.64714546 |
| 100 | Methylmalonic aciduria (HP:0012120) | 1.64270376 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 7.19641672 |
| 2 | TAF1 | 3.88425849 |
| 3 | MST4 | 3.33167868 |
| 4 | SMG1 | 3.22019280 |
| 5 | BCKDK | 2.96902735 |
| 6 | EIF2AK1 | 2.85477745 |
| 7 | STK16 | 2.83405347 |
| 8 | MAP2K6 | 2.82680817 |
| 9 | NUAK1 | 2.66736431 |
| 10 | EIF2AK3 | 2.64424755 |
| 11 | PDK2 | 2.62633364 |
| 12 | VRK1 | 2.49345251 |
| 13 | PIK3CA | 1.98169186 |
| 14 | BMPR2 | 1.88761459 |
| 15 | FRK | 1.85545338 |
| 16 | DAPK1 | 1.73173120 |
| 17 | SRPK1 | 1.64798826 |
| 18 | BUB1 | 1.61185798 |
| 19 | NME2 | 1.58567842 |
| 20 | ITK | 1.47273424 |
| 21 | TXK | 1.43393641 |
| 22 | PLK3 | 1.41361797 |
| 23 | NEK1 | 1.32370811 |
| 24 | BCR | 1.26982602 |
| 25 | EPHA4 | 1.21644905 |
| 26 | IKBKB | 1.20529195 |
| 27 | MAPKAPK5 | 1.17183670 |
| 28 | EIF2AK2 | 1.14713026 |
| 29 | GRK5 | 1.14521739 |
| 30 | STK39 | 1.12285759 |
| 31 | MELK | 1.02838667 |
| 32 | CSNK1G3 | 1.01700584 |
| 33 | ADRBK2 | 0.94097891 |
| 34 | KDR | 0.92832735 |
| 35 | PHKG1 | 0.92056389 |
| 36 | PHKG2 | 0.92056389 |
| 37 | WEE1 | 0.91156890 |
| 38 | LMTK2 | 0.90291763 |
| 39 | CSNK1A1L | 0.88631505 |
| 40 | PBK | 0.88103193 |
| 41 | CSNK1G2 | 0.87276209 |
| 42 | PLK4 | 0.86981276 |
| 43 | PRKCQ | 0.84719212 |
| 44 | INSRR | 0.84698770 |
| 45 | OXSR1 | 0.82010169 |
| 46 | CDK9 | 0.79966538 |
| 47 | MAP3K14 | 0.79586651 |
| 48 | CSNK1G1 | 0.79403406 |
| 49 | STK4 | 0.79108939 |
| 50 | DYRK2 | 0.78278869 |
| 51 | PINK1 | 0.78240823 |
| 52 | TLK1 | 0.75310055 |
| 53 | GRK1 | 0.73481384 |
| 54 | TRIM28 | 0.73288452 |
| 55 | MKNK2 | 0.69772517 |
| 56 | FGFR1 | 0.69222303 |
| 57 | TESK2 | 0.66383466 |
| 58 | TGFBR2 | 0.63780794 |
| 59 | ZAK | 0.63176820 |
| 60 | PLK2 | 0.62599637 |
| 61 | DAPK3 | 0.62451661 |
| 62 | CDK7 | 0.58702269 |
| 63 | TEC | 0.57389504 |
| 64 | BMPR1B | 0.54040760 |
| 65 | SYK | 0.50674407 |
| 66 | NEK6 | 0.47788567 |
| 67 | CDC7 | 0.46106438 |
| 68 | AURKB | 0.41910776 |
| 69 | PIK3CG | 0.40950095 |
| 70 | TBK1 | 0.40392300 |
| 71 | MAPKAPK2 | 0.39574177 |
| 72 | NEK9 | 0.39075519 |
| 73 | CAMK2G | 0.38141431 |
| 74 | MAP4K1 | 0.38071951 |
| 75 | ATR | 0.37874127 |
| 76 | MYLK | 0.37771996 |
| 77 | LCK | 0.35288499 |
| 78 | DAPK2 | 0.35236881 |
| 79 | ADRBK1 | 0.34264445 |
| 80 | BTK | 0.32880745 |
| 81 | CLK1 | 0.32627183 |
| 82 | CAMK2A | 0.31996286 |
| 83 | IKBKE | 0.31783648 |
| 84 | PLK1 | 0.31280025 |
| 85 | CHEK2 | 0.31248042 |
| 86 | LYN | 0.29493064 |
| 87 | CSNK2A1 | 0.29009761 |
| 88 | ARAF | 0.28799265 |
| 89 | TIE1 | 0.26653796 |
| 90 | TSSK6 | 0.26028221 |
| 91 | CSNK2A2 | 0.25436968 |
| 92 | TTK | 0.24798039 |
| 93 | JAK1 | 0.24558611 |
| 94 | CAMK2D | 0.24362567 |
| 95 | ACVR1B | 0.21465049 |
| 96 | GSK3A | 0.21045468 |
| 97 | PAK6 | 0.20104011 |
| 98 | HIPK2 | 0.19680989 |
| 99 | CHEK1 | 0.19422839 |
| 100 | MAPKAPK3 | 0.19342635 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.70796697 |
| 2 | Protein export_Homo sapiens_hsa03060 | 2.76164597 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 2.59320600 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.46570226 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.46198129 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.44354251 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.35862612 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.15257596 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.10517245 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.09744952 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.08561466 |
| 12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.05026637 |
| 13 | DNA replication_Homo sapiens_hsa03030 | 2.00835931 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.96469526 |
| 15 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.96345106 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.84860189 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.82147348 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.81905837 |
| 19 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.77906799 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.76413690 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.71358151 |
| 22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.71069306 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.70287956 |
| 24 | Base excision repair_Homo sapiens_hsa03410 | 1.56410139 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.55157529 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.53935106 |
| 27 | Ribosome_Homo sapiens_hsa03010 | 1.51028908 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.50478155 |
| 29 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.49566221 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.42808712 |
| 31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.32380275 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30349830 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.27034245 |
| 34 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.23286883 |
| 35 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.22007153 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.20394572 |
| 37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.20223750 |
| 38 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.19911967 |
| 39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.18597412 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 1.17675101 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.16444196 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15744096 |
| 43 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11463878 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.08340084 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 1.07728915 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 1.05667614 |
| 47 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.02341486 |
| 48 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.97591735 |
| 49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.96982831 |
| 50 | RNA transport_Homo sapiens_hsa03013 | 0.94487857 |
| 51 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.92736437 |
| 52 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.92492196 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89581087 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.86341682 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.84267049 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.80417089 |
| 57 | Mineral absorption_Homo sapiens_hsa04978 | 0.79855454 |
| 58 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.74170101 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.74086658 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.71731297 |
| 61 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.69155171 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.68496660 |
| 63 | Measles_Homo sapiens_hsa05162 | 0.66065441 |
| 64 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.64905203 |
| 65 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64300194 |
| 66 | Phototransduction_Homo sapiens_hsa04744 | 0.62964493 |
| 67 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.62661816 |
| 68 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.62553783 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61197919 |
| 70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57998512 |
| 71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.55823124 |
| 72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.50461884 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50381506 |
| 74 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.49559313 |
| 75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.47619333 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45189811 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45048515 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44835275 |
| 79 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.44613321 |
| 80 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44308662 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42829820 |
| 82 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.42521787 |
| 83 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41839396 |
| 84 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.41766454 |
| 85 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.41428859 |
| 86 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39826166 |
| 87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.39322885 |
| 88 | Viral myocarditis_Homo sapiens_hsa05416 | 0.38892101 |
| 89 | Cell cycle_Homo sapiens_hsa04110 | 0.37961596 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35459515 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34045373 |
| 92 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33450269 |
| 93 | Apoptosis_Homo sapiens_hsa04210 | 0.32965675 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.30106763 |
| 95 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.29054745 |
| 96 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27489580 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26254407 |
| 98 | Legionellosis_Homo sapiens_hsa05134 | 0.26226155 |
| 99 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.25000975 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.24855447 |

