SDSL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.12543739
2viral transcription (GO:0019083)6.09078071
3glyoxylate metabolic process (GO:0046487)5.85501254
4translational termination (GO:0006415)5.80244971
5DNA deamination (GO:0045006)5.72585441
6translational elongation (GO:0006414)5.19867079
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.17074151
8cotranslational protein targeting to membrane (GO:0006613)5.04731832
9protein targeting to ER (GO:0045047)5.02451938
10ribosomal small subunit biogenesis (GO:0042274)4.91613625
11protein localization to endoplasmic reticulum (GO:0070972)4.85310253
12establishment of protein localization to endoplasmic reticulum (GO:0072599)4.77803378
13viral life cycle (GO:0019058)4.43849208
14maturation of SSU-rRNA (GO:0030490)4.33532014
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.31803854
16cellular protein complex disassembly (GO:0043624)4.27317711
17positive regulation of lipoprotein lipase activity (GO:0051006)4.23875049
18positive regulation of triglyceride lipase activity (GO:0061365)4.23875049
19platelet dense granule organization (GO:0060155)4.19180915
20amyloid precursor protein catabolic process (GO:0042987)4.08252956
21deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.06185099
22translational initiation (GO:0006413)4.05595009
23complement activation, alternative pathway (GO:0006957)3.89925312
24serine family amino acid catabolic process (GO:0009071)3.85895570
25response to interferon-beta (GO:0035456)3.80087879
26epoxygenase P450 pathway (GO:0019373)3.79553112
27protein carboxylation (GO:0018214)3.78983904
28peptidyl-glutamic acid carboxylation (GO:0017187)3.78983904
29blood coagulation, intrinsic pathway (GO:0007597)3.78262312
30drug catabolic process (GO:0042737)3.70302059
31protein complex disassembly (GO:0043241)3.66997196
32L-phenylalanine metabolic process (GO:0006558)3.64861162
33erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.64861162
34definitive hemopoiesis (GO:0060216)3.63109640
35regulation of fibrinolysis (GO:0051917)3.60291094
36arginine catabolic process (GO:0006527)3.57558107
37negative regulation of cholesterol transport (GO:0032375)3.56438534
38negative regulation of sterol transport (GO:0032372)3.56438534
39pentose metabolic process (GO:0019321)3.52488490
40aldehyde catabolic process (GO:0046185)3.52304645
41oxidative phosphorylation (GO:0006119)3.50228246
42L-serine metabolic process (GO:0006563)3.48078046
43bile acid biosynthetic process (GO:0006699)3.47153761
44macromolecular complex disassembly (GO:0032984)3.46798808
45fibrinolysis (GO:0042730)3.46594672
46negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.44481571
47doxorubicin metabolic process (GO:0044598)3.43498737
48daunorubicin metabolic process (GO:0044597)3.43498737
49polyketide metabolic process (GO:0030638)3.43498737
50pseudouridine synthesis (GO:0001522)3.41637046
51glycosphingolipid catabolic process (GO:0046479)3.40728471
52ribosomal large subunit biogenesis (GO:0042273)3.40055902
53fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.37890853
54phospholipid efflux (GO:0033700)3.37679228
55pteridine-containing compound biosynthetic process (GO:0042559)3.35220517
56positive regulation of fatty acid biosynthetic process (GO:0045723)3.34108495
57translation (GO:0006412)3.34024110
58oxidative demethylation (GO:0070989)3.31437440
59omega-hydroxylase P450 pathway (GO:0097267)3.29200722
60proteasome assembly (GO:0043248)3.27554238
61L-phenylalanine catabolic process (GO:0006559)3.27347614
62erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.27347614
63negative regulation of erythrocyte differentiation (GO:0045647)3.25832249
64protein targeting to membrane (GO:0006612)3.25515903
65telomere maintenance via semi-conservative replication (GO:0032201)3.24094424
66negative regulation of fibrinolysis (GO:0051918)3.23532707
67nuclear-transcribed mRNA catabolic process (GO:0000956)3.22707284
68alkaloid metabolic process (GO:0009820)3.18684677
69cysteine metabolic process (GO:0006534)3.17034730
70heme biosynthetic process (GO:0006783)3.16436090
71heme metabolic process (GO:0042168)3.12642109
72metallo-sulfur cluster assembly (GO:0031163)3.11571346
73iron-sulfur cluster assembly (GO:0016226)3.11571346
74antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.10083859
75antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.10083859
76positive regulation of respiratory burst (GO:0060267)3.08683468
77mRNA catabolic process (GO:0006402)3.07503129
78tyrosine metabolic process (GO:0006570)3.06185206
79glycolipid catabolic process (GO:0019377)3.04691856
80mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.02234981
81mitochondrial respiratory chain complex I assembly (GO:0032981)3.02234981
82NADH dehydrogenase complex assembly (GO:0010257)3.02234981
83ribonucleoprotein complex biogenesis (GO:0022613)3.02129730
84aromatic amino acid family metabolic process (GO:0009072)3.01941382
85arginine metabolic process (GO:0006525)3.00991178
86respiratory chain complex IV assembly (GO:0008535)3.00582878
87fat-soluble vitamin biosynthetic process (GO:0042362)3.00415215
88amine catabolic process (GO:0009310)3.00404070
89cellular biogenic amine catabolic process (GO:0042402)3.00404070
90mitochondrial respiratory chain complex assembly (GO:0033108)2.99058627
91regulation of protein activation cascade (GO:2000257)2.98884367
92protein complex biogenesis (GO:0070271)2.98846131
93amino sugar catabolic process (GO:0046348)2.98364011
94xenobiotic catabolic process (GO:0042178)2.96870480
95serine family amino acid metabolic process (GO:0009069)2.96167447
96N-acetylneuraminate metabolic process (GO:0006054)2.94505533
97phenylpropanoid metabolic process (GO:0009698)2.94327733
98antigen processing and presentation via MHC class Ib (GO:0002475)2.93140036
99aerobic respiration (GO:0009060)2.93070214
100plasma lipoprotein particle clearance (GO:0034381)2.92692014
101cholesterol efflux (GO:0033344)2.90986266
102endosome to melanosome transport (GO:0035646)2.90479796
103endosome to pigment granule transport (GO:0043485)2.90479796
104regulation of triglyceride catabolic process (GO:0010896)2.89218165
105oligosaccharide catabolic process (GO:0009313)2.86592395
106ceramide catabolic process (GO:0046514)2.85768030
107exogenous drug catabolic process (GO:0042738)2.85118607
108RNA catabolic process (GO:0006401)2.84892969
109cellular component biogenesis (GO:0044085)2.84678933
110glycine metabolic process (GO:0006544)2.84353741
111DNA strand elongation (GO:0022616)2.83266106
112regulation of mitochondrial translation (GO:0070129)2.82878812
113cofactor catabolic process (GO:0051187)2.82738331
114mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.82197051
115DNA strand elongation involved in DNA replication (GO:0006271)2.81989184
116drug metabolic process (GO:0017144)2.81609570
117protein-lipid complex remodeling (GO:0034368)2.80330169
118macromolecular complex remodeling (GO:0034367)2.80330169
119plasma lipoprotein particle remodeling (GO:0034369)2.80330169
120aromatic amino acid family catabolic process (GO:0009074)2.80297269
121lysine metabolic process (GO:0006553)2.77707745
122lysine catabolic process (GO:0006554)2.77707745
123triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.77564990
124purine-containing compound salvage (GO:0043101)2.76634022
125tryptophan catabolic process (GO:0006569)2.76164897
126indole-containing compound catabolic process (GO:0042436)2.76164897
127indolalkylamine catabolic process (GO:0046218)2.76164897
128positive regulation of prostaglandin secretion (GO:0032308)2.75247628
129bile acid metabolic process (GO:0008206)2.74601113
130acylglycerol homeostasis (GO:0055090)2.73023619
131triglyceride homeostasis (GO:0070328)2.73023619
132cellular amino acid catabolic process (GO:0009063)2.71399227
133regulation of complement activation (GO:0030449)2.69331157
134serine family amino acid biosynthetic process (GO:0009070)2.69297027
135antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.68910837
136GDP-mannose metabolic process (GO:0019673)2.68723983
137positive regulation of cellular amine metabolic process (GO:0033240)2.68554102
138organic acid catabolic process (GO:0016054)2.67419142
139carboxylic acid catabolic process (GO:0046395)2.67419142
140response to interferon-alpha (GO:0035455)2.64930961
141flavonoid metabolic process (GO:0009812)2.64829415
142positive regulation of triglyceride metabolic process (GO:0090208)2.64125168
143purine nucleotide salvage (GO:0032261)2.64028698
144purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.62215010
145dopamine transport (GO:0015872)2.62162781
146high-density lipoprotein particle remodeling (GO:0034375)2.61974730
147cellular metabolic compound salvage (GO:0043094)2.60998244
148nucleoside salvage (GO:0043174)2.60977153
149alpha-amino acid catabolic process (GO:1901606)2.60771723
150sulfur amino acid catabolic process (GO:0000098)2.59557661
151nucleotide salvage (GO:0043173)2.59209999
152secretory granule organization (GO:0033363)2.59199032
153L-methionine salvage (GO:0071267)2.58668426
154L-methionine biosynthetic process (GO:0071265)2.58668426
155amino acid salvage (GO:0043102)2.58668426
156L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.58617523
157proline metabolic process (GO:0006560)2.57890855
158sphingolipid catabolic process (GO:0030149)2.55889229
159protein autoprocessing (GO:0016540)2.55157592
160positive regulation of lymphocyte apoptotic process (GO:0070230)2.54990596
161vitamin biosynthetic process (GO:0009110)2.54668526
162telomere maintenance via recombination (GO:0000722)2.54281686
163valine metabolic process (GO:0006573)2.54105912
164steroid catabolic process (GO:0006706)2.53822467
165energy coupled proton transport, down electrochemical gradient (GO:0015985)2.51857781
166ATP synthesis coupled proton transport (GO:0015986)2.51857781
167drug transmembrane transport (GO:0006855)2.51837809
168toxin transport (GO:1901998)2.51175496
169monocarboxylic acid catabolic process (GO:0072329)2.51125182
170regulation of cholesterol esterification (GO:0010872)2.51040096
171sulfur amino acid biosynthetic process (GO:0000097)2.51000680
172ethanol oxidation (GO:0006069)2.50055803
173membrane lipid catabolic process (GO:0046466)2.50006658
174drug transport (GO:0015893)2.49171297
175urea cycle (GO:0000050)2.48959564
176urea metabolic process (GO:0019627)2.48959564
177amyloid precursor protein metabolic process (GO:0042982)2.48677466
178nitrogen cycle metabolic process (GO:0071941)2.48063697
179positive regulation of icosanoid secretion (GO:0032305)2.47813539
180uronic acid metabolic process (GO:0006063)2.45272322
181glucuronate metabolic process (GO:0019585)2.45272322
182vitamin D metabolic process (GO:0042359)2.44115407
183acute-phase response (GO:0006953)2.43050412

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.15655639
2* ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.14563851
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.83199363
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.78179039
5SCL_19346495_ChIP-Seq_HPC-7_Human3.06569053
6E2F7_22180533_ChIP-Seq_HELA_Human3.05270578
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.94143317
8PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.82377107
9TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.68341554
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.64812944
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.63768220
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.63510369
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59623830
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.58249234
15CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.50660239
16* RXR_22158963_ChIP-Seq_LIVER_Mouse2.49614096
17EGR1_23403033_ChIP-Seq_LIVER_Mouse2.47491113
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.43746420
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.43539904
20GATA1_22025678_ChIP-Seq_K562_Human2.43206955
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.41757474
22FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.41289237
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.40943888
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.38927386
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.32160949
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.30863961
27LXR_22292898_ChIP-Seq_THP-1_Human2.29517658
28* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.21939758
29CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.21783559
30SRF_21415370_ChIP-Seq_HL-1_Mouse2.13900636
31ERG_20887958_ChIP-Seq_HPC-7_Mouse2.04623207
32MYC_19030024_ChIP-ChIP_MESCs_Mouse2.02590754
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.01309925
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.97488458
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.92784879
36ELF1_20517297_ChIP-Seq_JURKAT_Human1.92735881
37VDR_23849224_ChIP-Seq_CD4+_Human1.92675909
38FOXP3_21729870_ChIP-Seq_TREG_Human1.92040476
39* TET1_21451524_ChIP-Seq_MESCs_Mouse1.91777682
40XRN2_22483619_ChIP-Seq_HELA_Human1.90611599
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.90274918
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.87602404
43LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.84175879
44GATA1_22383799_ChIP-Seq_G1ME_Mouse1.83891629
45MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.81793034
46BCL6_27268052_Chip-Seq_Bcells_Human1.81437609
47BP1_19119308_ChIP-ChIP_Hs578T_Human1.76013883
48IRF8_21731497_ChIP-ChIP_J774_Mouse1.73689004
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.72046023
50SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.71882530
51CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.71016990
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.69262549
53CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.68777400
54GABP_19822575_ChIP-Seq_HepG2_Human1.63820707
55CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.59026301
56BCOR_27268052_Chip-Seq_Bcells_Human1.58586026
57IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.58457002
58P68_20966046_ChIP-Seq_HELA_Human1.57431517
59DCP1A_22483619_ChIP-Seq_HELA_Human1.57065396
60THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.53884409
61* IRF8_22096565_ChIP-ChIP_GC-B_Human1.53339872
62ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52793076
63HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.49768920
64SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.49149899
65E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.48280649
66* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.46797618
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46363828
68NELFA_20434984_ChIP-Seq_ESCs_Mouse1.43905645
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43360405
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.41050000
71MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.40481451
72TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.40301578
73PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40029763
74RBPJ_22232070_ChIP-Seq_NCS_Mouse1.39721315
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.37694146
76ZNF263_19887448_ChIP-Seq_K562_Human1.37364527
77STAT6_21828071_ChIP-Seq_BEAS2B_Human1.37165819
78RARG_19884340_ChIP-ChIP_MEFs_Mouse1.36873651
79* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.36582227
80FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.35926920
81TTF2_22483619_ChIP-Seq_HELA_Human1.35329129
82SPI1_23547873_ChIP-Seq_NB4_Human1.35314679
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.34835407
84E2F1_20622854_ChIP-Seq_HELA_Human1.34307933
85CIITA_25753668_ChIP-Seq_RAJI_Human1.34221838
86GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.33522512
87* LXR_22158963_ChIP-Seq_LIVER_Mouse1.32155042
88YY1_22570637_ChIP-Seq_MALME-3M_Human1.31662908
89ESR1_15608294_ChIP-ChIP_MCF-7_Human1.31505454
90RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.30975981
91GATA2_22383799_ChIP-Seq_G1ME_Mouse1.29138818
92E2F4_17652178_ChIP-ChIP_JURKAT_Human1.28630716
93* GATA1_19941827_ChIP-Seq_MEL_Mouse1.26556391
94PHF8_20622854_ChIP-Seq_HELA_Human1.26080620
95CTCF_18555785_ChIP-Seq_MESCs_Mouse1.26057398
96BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.25565546
97STAT3_1855785_ChIP-Seq_MESCs_Mouse1.25231997
98MYB_21317192_ChIP-Seq_ERMYB_Mouse1.24373652
99FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.24212270
100SA1_27219007_Chip-Seq_ERYTHROID_Human1.24043749
101VDR_21846776_ChIP-Seq_THP-1_Human1.23869609
102RACK7_27058665_Chip-Seq_MCF-7_Human1.23277115
103YY1_21170310_ChIP-Seq_MESCs_Mouse1.22565090
104* CTCF_20526341_ChIP-Seq_ESCs_Human1.21820527
105TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21320290
106PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.20284300
107MYC_22102868_ChIP-Seq_BL_Human1.19288854
108ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.16959983
109* SA1_27219007_Chip-Seq_Bcells_Human1.16689800
110* STAT1_20625510_ChIP-Seq_HELA_Human1.16280354
111PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16217341
112MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15587846
113NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.15395919
114* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13224460
115SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.13122548
116CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12434029
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.11250223
118CTCF_21964334_Chip-Seq_Bcells_Human1.11155022
119ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10603480
120FOXP1_21924763_ChIP-Seq_HESCs_Human1.08683358
121TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08585929
122MYC_18940864_ChIP-ChIP_HL60_Human1.07951128
123RUNX1_22412390_ChIP-Seq_EML_Mouse1.07066836
124ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.05330665
125ERG_21242973_ChIP-ChIP_JURKAT_Human1.04393067
126RXRA_24833708_ChIP-Seq_LIVER_Mouse1.04057226
127SPI1_20517297_ChIP-Seq_HL60_Human1.02224061
128* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.02046054
129ELK1_19687146_ChIP-ChIP_HELA_Human1.02005524
130TFEB_21752829_ChIP-Seq_HELA_Human1.01767941
131VDR_24763502_ChIP-Seq_THP-1_Human1.01482979
132P300_27268052_Chip-Seq_Bcells_Human1.01468454
133PU.1_20513432_ChIP-Seq_Bcells_Mouse1.00867473
134BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00415509
135RARA_24833708_ChIP-Seq_LIVER_Mouse1.00410533
136CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.00149022
137DNAJC2_21179169_ChIP-ChIP_NT2_Human1.00057866
138CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99456574
139CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98776147
140IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.98469441
141CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97849716
142CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96742437
143CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96734156
144CTCF_26484167_Chip-Seq_Bcells_Mouse0.93395297
145MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.92283154
146STAT4_19710469_ChIP-ChIP_TH1__Mouse0.88260671
147MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.87926514
148MYCN_18555785_ChIP-Seq_MESCs_Mouse0.86991588
149E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.86246670
150E2F1_21310950_ChIP-Seq_MCF-7_Human0.85734037
151IRF1_19129219_ChIP-ChIP_H3396_Human0.85518252
152SRY_22984422_ChIP-ChIP_TESTIS_Rat0.83798495
153EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.83627040

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.57156815
2MP0005058_abnormal_lysosome_morphology4.49983729
3MP0005360_urolithiasis3.78233866
4MP0005085_abnormal_gallbladder_physiolo3.72749377
5MP0003806_abnormal_nucleotide_metabolis3.67644267
6MP0005365_abnormal_bile_salt3.66470248
7MP0004147_increased_porphyrin_level3.53846609
8MP0003656_abnormal_erythrocyte_physiolo3.50816347
9MP0009379_abnormal_foot_pigmentation3.33088412
10MP0002396_abnormal_hematopoietic_system2.92818999
11MP0005397_hematopoietic_system_phenotyp2.73278326
12MP0001545_abnormal_hematopoietic_system2.73278326
13MP0008875_abnormal_xenobiotic_pharmacok2.69864485
14MP0003186_abnormal_redox_activity2.52050610
15MP0006036_abnormal_mitochondrial_physio2.48114017
16MP0006054_spinal_hemorrhage2.47721854
17MP0003724_increased_susceptibility_to2.24557590
18MP0000604_amyloidosis2.13433858
19MP0003172_abnormal_lysosome_physiology2.12560601
20MP0003075_altered_response_to2.10082654
21MP0001666_abnormal_nutrient_absorption2.02574746
22MP0005464_abnormal_platelet_physiology2.01994654
23MP0010329_abnormal_lipoprotein_level1.96730270
24MP0002132_abnormal_respiratory_system1.91860986
25MP0002148_abnormal_hypersensitivity_rea1.91787350
26MP0009697_abnormal_copulation1.89736139
27MP0005075_abnormal_melanosome_morpholog1.88831746
28MP0001764_abnormal_homeostasis1.86942722
29MP0009840_abnormal_foam_cell1.85527593
30MP0005174_abnormal_tail_pigmentation1.85209732
31MP0000490_abnormal_crypts_of1.83428499
32MP0004808_abnormal_hematopoietic_stem1.80805205
33MP0005083_abnormal_biliary_tract1.77564461
34MP0005332_abnormal_amino_acid1.73355663
35MP0003191_abnormal_cellular_cholesterol1.73330923
36MP0001835_abnormal_antigen_presentation1.73038682
37MP0005319_abnormal_enzyme/_coenzyme1.72930547
38MP0006082_CNS_inflammation1.69443356
39MP0000465_gastrointestinal_hemorrhage1.68381607
40MP0003868_abnormal_feces_composition1.63100178
41MP0002876_abnormal_thyroid_physiology1.59615217
42MP0005636_abnormal_mineral_homeostasis1.54257759
43MP0005451_abnormal_body_composition1.52851449
44MP0005584_abnormal_enzyme/coenzyme_acti1.50794497
45MP0001873_stomach_inflammation1.50529327
46MP0006035_abnormal_mitochondrial_morpho1.49460299
47MP0003252_abnormal_bile_duct1.45776271
48MP0008469_abnormal_protein_level1.36468376
49MP0003303_peritoneal_inflammation1.34090954
50MP0000609_abnormal_liver_physiology1.33283696
51MP0001853_heart_inflammation1.33076337
52MP0009785_altered_susceptibility_to1.31891519
53MP0003436_decreased_susceptibility_to1.31670839
54MP0005220_abnormal_exocrine_pancreas1.31117104
55MP0000685_abnormal_immune_system1.30649876
56MP0003693_abnormal_embryo_hatching1.29180739
57MP0001986_abnormal_taste_sensitivity1.28863386
58MP0003763_abnormal_thymus_physiology1.27486030
59MP0002837_dystrophic_cardiac_calcinosis1.27038769
60MP0002254_reproductive_system_inflammat1.26828811
61MP0000678_abnormal_parathyroid_gland1.25932081
62MP0002095_abnormal_skin_pigmentation1.24755399
63MP0000681_abnormal_thyroid_gland1.24150843
64MP0009643_abnormal_urine_homeostasis1.23300016
65MP0003866_abnormal_defecation1.21536058
66MP0005166_decreased_susceptibility_to1.18670078
67MP0010155_abnormal_intestine_physiology1.17153812
68MP0003879_abnormal_hair_cell1.16871827
69MP0000598_abnormal_liver_morphology1.16665579
70MP0000689_abnormal_spleen_morphology1.15398623
71MP0005084_abnormal_gallbladder_morpholo1.15106024
72MP0003329_amyloid_beta_deposits1.14812320
73MP0002398_abnormal_bone_marrow1.13470497
74MP0003011_delayed_dark_adaptation1.13370516
75MP0005671_abnormal_response_to1.13278817
76MP0002653_abnormal_ependyma_morphology1.12403516
77MP0005025_abnormal_response_to1.10988978
78MP0004957_abnormal_blastocyst_morpholog1.09366318
79MP0002118_abnormal_lipid_homeostasis1.07610926
80MP0009278_abnormal_bone_marrow1.05848415
81MP0001663_abnormal_digestive_system1.04709157
82MP0008260_abnormal_autophagy1.04588067
83MP0002166_altered_tumor_susceptibility1.04283418
84MP0002722_abnormal_immune_system1.04200209
85MP0005408_hypopigmentation1.03368456
86MP0002429_abnormal_blood_cell1.00673904
87MP0004510_myositis0.97977606
88MP0003638_abnormal_response/metabolism_0.96305583
89MP0009333_abnormal_splenocyte_physiolog0.95582792
90MP0009763_increased_sensitivity_to0.94069832
91MP0009764_decreased_sensitivity_to0.91432019
92MP0002234_abnormal_pharynx_morphology0.89534861
93MP0008007_abnormal_cellular_replicative0.88514892
94MP0009642_abnormal_blood_homeostasis0.87238605
95MP0004019_abnormal_vitamin_homeostasis0.87005074
96MP0008872_abnormal_physiological_respon0.86628772
97MP0005379_endocrine/exocrine_gland_phen0.85367205
98MP0000716_abnormal_immune_system0.84330340
99MP0001533_abnormal_skeleton_physiology0.84049393
100MP0003195_calcinosis0.81998119
101MP0005165_increased_susceptibility_to0.81313369
102MP0001790_abnormal_immune_system0.81191747
103MP0005387_immune_system_phenotype0.81191747
104MP0010094_abnormal_chromosome_stability0.81112169
105MP0002090_abnormal_vision0.80804717
106MP0001756_abnormal_urination0.80651388
107MP0001845_abnormal_inflammatory_respons0.80604894
108MP0003943_abnormal_hepatobiliary_system0.80529141
109MP0001348_abnormal_lacrimal_gland0.79991885
110MP0005000_abnormal_immune_tolerance0.79484575
111MP0002723_abnormal_immune_serum0.78354853
112MP0001800_abnormal_humoral_immune0.77232465
113MP0005535_abnormal_body_temperature0.77065886
114MP0004215_abnormal_myocardial_fiber0.76604141
115MP0010386_abnormal_urinary_bladder0.75677777
116MP0005167_abnormal_blood-brain_barrier0.75076175
117MP0005266_abnormal_metabolism0.74929911
118MP0000343_altered_response_to0.73882378
119MP0005376_homeostasis/metabolism_phenot0.73729657
120MP0000358_abnormal_cell_content/0.73719972
121MP0002420_abnormal_adaptive_immunity0.73438351
122MP0008058_abnormal_DNA_repair0.72809592
123MP0002138_abnormal_hepatobiliary_system0.72348199
124MP0001819_abnormal_immune_cell0.70824467
125MP0002019_abnormal_tumor_incidence0.70163878
126MP0001881_abnormal_mammary_gland0.70136999
127MP0002452_abnormal_antigen_presenting0.70051198
128MP0001905_abnormal_dopamine_level0.69902759
129MP0000313_abnormal_cell_death0.69535027
130MP0003077_abnormal_cell_cycle0.68989474
131MP0010368_abnormal_lymphatic_system0.68479796
132MP0002419_abnormal_innate_immunity0.68003044
133MP0003567_abnormal_fetal_cardiomyocyte0.66911307
134MP0005647_abnormal_sex_gland0.65981607
135MP0002006_tumorigenesis0.65084288
136MP0000477_abnormal_intestine_morphology0.64883829
137MP0005646_abnormal_pituitary_gland0.64728741
138MP0000858_altered_metastatic_potential0.62500321
139MP0002136_abnormal_kidney_physiology0.61344019
140MP0008874_decreased_physiological_sensi0.60831629
141MP0005410_abnormal_fertilization0.60362740
142MP0002822_catalepsy0.60136074
143MP0003453_abnormal_keratinocyte_physiol0.58782135
144MP0003690_abnormal_glial_cell0.58640242

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)6.49847040
2Abnormality of cells of the erythroid lineage (HP:0012130)6.39507250
3Abnormality of the heme biosynthetic pathway (HP:0010472)6.06086200
4Abnormality of liposaccharide metabolism (HP:0010968)5.98405378
5Abnormality of glycosphingolipid metabolism (HP:0004343)5.98405378
6Abnormality of glycolipid metabolism (HP:0010969)5.98405378
7Systemic lupus erythematosus (HP:0002725)5.02968698
8Abnormality of aromatic amino acid family metabolism (HP:0004338)4.62834291
9Aplastic anemia (HP:0001915)4.36649748
10Increased cerebral lipofuscin (HP:0011813)4.19354256
11Vacuolated lymphocytes (HP:0001922)4.13186126
12Prolonged bleeding time (HP:0003010)4.06415004
13Petechiae (HP:0000967)4.01745092
14Complement deficiency (HP:0004431)3.95783028
15Increased neuronal autofluorescent lipopigment (HP:0002074)3.87792212
16Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.80651355
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.80651355
18Hepatic necrosis (HP:0002605)3.66824690
19Increased intramyocellular lipid droplets (HP:0012240)3.62965201
20Pallor (HP:0000980)3.61068216
21Reticulocytopenia (HP:0001896)3.59530014
22Increased muscle lipid content (HP:0009058)3.56078892
23Hepatocellular necrosis (HP:0001404)3.49729844
24Glomerulonephritis (HP:0000099)3.46199192
25Dysostosis multiplex (HP:0000943)3.37874063
26Lipid accumulation in hepatocytes (HP:0006561)3.29767394
27Thrombocytosis (HP:0001894)3.26043109
28Abnormality of polysaccharide metabolism (HP:0011012)3.24902920
29Abnormality of glycosaminoglycan metabolism (HP:0004371)3.24902920
30Abnormality of mucopolysaccharide metabolism (HP:0011020)3.24902920
31Macrocytic anemia (HP:0001972)3.23608026
32Reduced antithrombin III activity (HP:0001976)3.21235569
33Prolonged neonatal jaundice (HP:0006579)3.16630030
34Epistaxis (HP:0000421)3.15546798
35Increased hepatocellular lipid droplets (HP:0006565)3.15493023
36Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.14989409
37Abnormality of complement system (HP:0005339)3.12317490
383-Methylglutaconic aciduria (HP:0003535)3.04171718
39Abnormality of monocarboxylic acid metabolism (HP:0010996)3.01946044
40Mucopolysacchariduria (HP:0008155)3.01258466
41Urinary glycosaminoglycan excretion (HP:0003541)3.01258466
42Mitochondrial inheritance (HP:0001427)2.92754720
43Generalized aminoaciduria (HP:0002909)2.92062922
44Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.91008005
45Intrahepatic cholestasis (HP:0001406)2.89451501
46Type I transferrin isoform profile (HP:0003642)2.84693588
47Hyperammonemia (HP:0001987)2.81962506
48Hypobetalipoproteinemia (HP:0003563)2.80753017
49Abnormal platelet function (HP:0011869)2.79964022
50Impaired platelet aggregation (HP:0003540)2.79964022
51Hyperbilirubinemia (HP:0002904)2.79262499
52Purpura (HP:0000979)2.78305073
53Increased CSF lactate (HP:0002490)2.76648064
54Renal Fanconi syndrome (HP:0001994)2.74942458
55Loss of speech (HP:0002371)2.74869133
56Lactic acidosis (HP:0003128)2.74866345
57Increased serum lactate (HP:0002151)2.73907413
58Increased serum ferritin (HP:0003281)2.71673015
59Microcytic anemia (HP:0001935)2.71102175
60Acanthocytosis (HP:0001927)2.70242687
61Dicarboxylic aciduria (HP:0003215)2.67545108
62Abnormality of dicarboxylic acid metabolism (HP:0010995)2.67545108
63Hyperthyroidism (HP:0000836)2.67276417
64Muscle fiber atrophy (HP:0100295)2.66048018
65Type 2 muscle fiber atrophy (HP:0003554)2.65865590
66Abnormal gallbladder physiology (HP:0012438)2.63251311
67Cholecystitis (HP:0001082)2.63251311
68Progressive neurologic deterioration (HP:0002344)2.62371906
69Hypoglycemic coma (HP:0001325)2.62231883
70Abnormality of fatty-acid metabolism (HP:0004359)2.56559394
71Abnormality of the intrinsic pathway (HP:0010989)2.55244543
72Abnormal mitochondria in muscle tissue (HP:0008316)2.51982608
73Gingival bleeding (HP:0000225)2.51260698
74Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.50067619
75Axonal loss (HP:0003447)2.47111376
76Acute encephalopathy (HP:0006846)2.46430360
77IgM deficiency (HP:0002850)2.44992332
78Prolonged partial thromboplastin time (HP:0003645)2.44478381
79Exertional dyspnea (HP:0002875)2.42385337
80Cerebral edema (HP:0002181)2.41072050
81Ragged-red muscle fibers (HP:0003200)2.40652034
82Nuclear cataract (HP:0100018)2.40524713
83Abnormality of iron homeostasis (HP:0011031)2.40514725
84Menorrhagia (HP:0000132)2.40352257
85Oral leukoplakia (HP:0002745)2.37935641
86Abnormal protein glycosylation (HP:0012346)2.37302636
87Abnormal glycosylation (HP:0012345)2.37302636
88Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.37302636
89Abnormal protein N-linked glycosylation (HP:0012347)2.37302636
90Acute necrotizing encephalopathy (HP:0006965)2.34486253
91Ketosis (HP:0001946)2.31390063
92Nausea (HP:0002018)2.31114675
93Abnormality of methionine metabolism (HP:0010901)2.29323948
94Pancytopenia (HP:0001876)2.29079171
95Hypertensive crisis (HP:0100735)2.27703292
96Recurrent gram-negative bacterial infections (HP:0005420)2.27285419
97Abnormality of transition element cation homeostasis (HP:0011030)2.24334563
98Abnormality of reticulocytes (HP:0004312)2.23551478
99Glycosuria (HP:0003076)2.22670330
100Abnormality of urine glucose concentration (HP:0011016)2.22670330
101Chronic otitis media (HP:0000389)2.22257726
102Recurrent abscess formation (HP:0002722)2.21086304
103Mesangial abnormality (HP:0001966)2.20678061
104Retinal atrophy (HP:0001105)2.19955647
105Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.19345564
106Poikilocytosis (HP:0004447)2.18275389
107Delayed CNS myelination (HP:0002188)2.18102193
108Abnormality of aspartate family amino acid metabolism (HP:0010899)2.17948039
109J-shaped sella turcica (HP:0002680)2.15713529
110Respiratory difficulties (HP:0002880)2.15367490
111Microvesicular hepatic steatosis (HP:0001414)2.15353436
112Lethargy (HP:0001254)2.15273296
113Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.13102194
114Mutism (HP:0002300)2.12833208
115Cardiomegaly (HP:0001640)2.12630925
116Abnormality of glutamine family amino acid metabolism (HP:0010902)2.08097147
117Sensorimotor neuropathy (HP:0007141)2.07835557
118Abnormality of serum amino acid levels (HP:0003112)2.06992589
119Conjugated hyperbilirubinemia (HP:0002908)2.06657261
120Hypokinesia (HP:0002375)2.06393876
121Cholelithiasis (HP:0001081)2.06370104
122Abnormality of pyrimidine metabolism (HP:0004353)2.05779276
123Recurrent bacterial skin infections (HP:0005406)2.05686435
124Exercise intolerance (HP:0003546)2.04833192
125Microretrognathia (HP:0000308)2.04323147
126Brushfield spots (HP:0001088)2.04060728
127Xanthomatosis (HP:0000991)2.02443744
128Late onset (HP:0003584)2.02322836
129Progressive muscle weakness (HP:0003323)2.00210417
130Amyloidosis (HP:0011034)1.99798893
131Hyperlipoproteinemia (HP:0010980)1.99457488
132Abnormality of the common coagulation pathway (HP:0010990)1.99410174
133Abnormal pupillary function (HP:0007686)1.98084817
134Obstructive lung disease (HP:0006536)1.98056258
135Chronic obstructive pulmonary disease (HP:0006510)1.98056258
136Disinhibition (HP:0000734)1.97145163
137Vertebral compression fractures (HP:0002953)1.96469697
138Nephritis (HP:0000123)1.94712292
139Respiratory failure (HP:0002878)1.94465116
140Deep venous thrombosis (HP:0002625)1.92627540
141Metabolic acidosis (HP:0001942)1.91566806
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90443512
143Progressive macrocephaly (HP:0004481)1.90025539
144Upper motor neuron abnormality (HP:0002127)1.88686821
145Abnormal gallbladder morphology (HP:0012437)1.88666095
146Joint hemorrhage (HP:0005261)1.87496186
147Cerebral palsy (HP:0100021)1.86317208
148Absent rod-and cone-mediated responses on ERG (HP:0007688)1.86002999
14911 pairs of ribs (HP:0000878)1.85917636
150Vomiting (HP:0002013)1.85156088
151Hyperglycinemia (HP:0002154)1.84062666
152Abnormality of sulfur amino acid metabolism (HP:0004339)1.83914557
153Hyperalaninemia (HP:0003348)1.82176657
154Truncus arteriosus (HP:0001660)1.78685042
155Double outlet right ventricle (HP:0001719)1.78261408
156Congenital malformation of the right heart (HP:0011723)1.78261408
157Abnormality of macrophages (HP:0004311)1.78157255
158Delusions (HP:0000746)1.77625702

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.41023559
2VRK24.22468412
3MUSK3.86763089
4NME23.83601217
5BCKDK3.21867067
6CDK192.74121256
7SMG12.52307312
8TAOK22.41178636
9TGFBR12.32735472
10TESK22.31322308
11TESK12.26431224
12VRK12.24528988
13KIT2.21507348
14FLT32.18244065
15PRKD32.03813876
16EEF2K2.02133560
17WEE12.01784378
18PKN22.01725616
19TAF11.98224196
20MAP3K121.92463404
21MAP2K31.92355018
22MAP4K11.86246596
23PIM21.82205503
24TIE11.81249837
25SCYL21.78429188
26DYRK31.72825200
27LIMK11.72267157
28RPS6KB21.71971425
29KDR1.68130602
30MAPKAPK31.67315071
31TAOK31.64644496
32MATK1.61982246
33TGFBR21.56087936
34PRKG21.53780551
35MAPKAPK51.53395168
36TNIK1.53036605
37MAP2K61.52351747
38EIF2AK11.52160351
39ARAF1.44308413
40BTK1.42688960
41ERN11.42169981
42TEC1.27536020
43ACVR1B1.27340404
44TBK11.26283542
45GRK71.25093406
46PASK1.23474712
47MYLK1.19615482
48CDK81.19104092
49JAK31.12698522
50DAPK31.12018978
51ZAP701.11117340
52IRAK31.10285448
53EPHA21.09358381
54EPHB21.08462800
55MAP3K111.07551095
56CSNK1G21.07089315
57CSNK1A1L1.03736411
58TNK21.02704496
59LRRK21.00504371
60BRSK20.97863332
61PINK10.97412733
62SRPK10.96690607
63ADRBK20.94791773
64TAOK10.93461108
65EIF2AK30.92452984
66IRAK20.92228001
67IRAK40.90742991
68MKNK10.90312310
69RPS6KA40.89948011
70LMTK20.88457364
71IKBKE0.87747855
72BLK0.86903829
73CCNB10.83286982
74NME10.81448416
75TLK10.80777271
76CSF1R0.78777320
77CDK70.77391547
78NEK90.76710926
79SIK10.76107871
80PBK0.75955768
81TRIB30.75706440
82MAPK110.73786695
83SYK0.72672052
84MAP3K70.72492521
85TYK20.70609294
86PIK3CG0.69810819
87CAMK10.69579850
88MAP3K10.68185216
89CDC70.67833921
90PRKCI0.67699488
91PIM10.67218874
92MAP2K20.67143712
93DDR20.66655943
94DAPK10.66220298
95NUAK10.66058898
96ILK0.65720718
97ICK0.64162334
98PDK20.62886520
99PAK40.61973061
100NEK20.61677246
101MAP3K30.59061868
102LYN0.58604029
103PRPF4B0.58110296
104CAMKK20.56154154
105DYRK20.56148571
106CDK90.54992236
107MAPK40.54978906
108IKBKB0.53748648
109MAPK150.53718802
110FGFR40.53663640
111AURKB0.52730607
112JAK20.52250515
113GRK50.51381870
114NLK0.51012059
115CAMK1D0.50541904
116GRK10.48627139
117ATR0.48393371
118TXK0.48275549
119CSNK1G30.46883872
120CHUK0.46435069
121CDK40.45861869
122ABL20.45606051
123GSK3A0.43616241
124MAP2K70.43006769
125CAMK2G0.42914801
126CSNK2A10.41232651
127CSNK2A20.40690118
128RPS6KL10.39616128
129RPS6KC10.39616128
130MST1R0.39272819
131BRAF0.37150057
132MAP3K50.36579779
133CAMK2D0.35760123
134DYRK1B0.34196812
135RPS6KA60.32866353
136CSNK1G10.31768945
137PLK10.31105561
138MAP3K140.31048094
139CSNK1A10.30533555
140MAPK30.30365611
141PRKCD0.29924481
142RPS6KA50.29779409
143AURKA0.29717020
144PDPK10.29021150
145HIPK20.28130058
146RPS6KA20.27330929
147PAK10.27083509
148GRK60.27045916
149TSSK60.26546099
150ERBB20.24665337

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.71284310
2DNA replication_Homo sapiens_hsa030303.07206244
3Other glycan degradation_Homo sapiens_hsa005113.00127488
4Folate biosynthesis_Homo sapiens_hsa007902.70801316
5Primary bile acid biosynthesis_Homo sapiens_hsa001202.43953943
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.41523225
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.30839876
8Mismatch repair_Homo sapiens_hsa034302.15970920
9Pyrimidine metabolism_Homo sapiens_hsa002402.09908876
10Lysosome_Homo sapiens_hsa041422.09284210
11Fatty acid degradation_Homo sapiens_hsa000712.06785171
12Caffeine metabolism_Homo sapiens_hsa002322.04418074
13Sulfur relay system_Homo sapiens_hsa041221.99674804
14Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.95092209
15Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.87093500
16Drug metabolism - other enzymes_Homo sapiens_hsa009831.79063685
17Selenocompound metabolism_Homo sapiens_hsa004501.78484614
18RNA polymerase_Homo sapiens_hsa030201.71236912
19Parkinsons disease_Homo sapiens_hsa050121.70672603
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.67138739
21Proteasome_Homo sapiens_hsa030501.64294880
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.62342625
23Peroxisome_Homo sapiens_hsa041461.62132303
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61004382
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.60545900
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.58530529
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.53883214
28Protein export_Homo sapiens_hsa030601.48955815
29Propanoate metabolism_Homo sapiens_hsa006401.48874036
30* Cysteine and methionine metabolism_Homo sapiens_hsa002701.47442762
31Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.44304180
32Tryptophan metabolism_Homo sapiens_hsa003801.44103510
33Base excision repair_Homo sapiens_hsa034101.42572779
34One carbon pool by folate_Homo sapiens_hsa006701.41917649
35Homologous recombination_Homo sapiens_hsa034401.39977333
36Pentose phosphate pathway_Homo sapiens_hsa000301.39613404
37Oxidative phosphorylation_Homo sapiens_hsa001901.36215391
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.30844903
39Nucleotide excision repair_Homo sapiens_hsa034201.30591272
40Maturity onset diabetes of the young_Homo sapiens_hsa049501.30015458
41Pyruvate metabolism_Homo sapiens_hsa006201.29593032
42Arginine biosynthesis_Homo sapiens_hsa002201.25830839
43Spliceosome_Homo sapiens_hsa030401.20404881
44Fatty acid metabolism_Homo sapiens_hsa012121.17203286
45Complement and coagulation cascades_Homo sapiens_hsa046101.14418409
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.13543006
47Chemical carcinogenesis_Homo sapiens_hsa052041.11798415
48Nitrogen metabolism_Homo sapiens_hsa009101.10921392
49* Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10343608
50Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.07939825
51Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.06742431
52Histidine metabolism_Homo sapiens_hsa003401.05869331
53Rheumatoid arthritis_Homo sapiens_hsa053231.04661851
54beta-Alanine metabolism_Homo sapiens_hsa004101.04630649
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.03359523
56Fatty acid elongation_Homo sapiens_hsa000621.02856579
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02211578
58* Carbon metabolism_Homo sapiens_hsa012001.01779146
59Arachidonic acid metabolism_Homo sapiens_hsa005901.01228941
60Huntingtons disease_Homo sapiens_hsa050160.99881380
61Asthma_Homo sapiens_hsa053100.99437070
62* Biosynthesis of amino acids_Homo sapiens_hsa012300.99134334
63PPAR signaling pathway_Homo sapiens_hsa033200.98787888
64Galactose metabolism_Homo sapiens_hsa000520.98381003
65Prion diseases_Homo sapiens_hsa050200.97863779
66Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.97525897
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96532853
68Purine metabolism_Homo sapiens_hsa002300.95968324
69Glutathione metabolism_Homo sapiens_hsa004800.93980499
70N-Glycan biosynthesis_Homo sapiens_hsa005100.93746725
71Collecting duct acid secretion_Homo sapiens_hsa049660.92059822
72Alzheimers disease_Homo sapiens_hsa050100.91823076
73Fat digestion and absorption_Homo sapiens_hsa049750.89537902
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89339760
75ABC transporters_Homo sapiens_hsa020100.88056414
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.87336339
77RNA degradation_Homo sapiens_hsa030180.87270510
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.84753023
79* Metabolic pathways_Homo sapiens_hsa011000.84575313
80Sulfur metabolism_Homo sapiens_hsa009200.84187303
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81828077
82Retinol metabolism_Homo sapiens_hsa008300.81388414
83Fructose and mannose metabolism_Homo sapiens_hsa000510.81338729
84Cyanoamino acid metabolism_Homo sapiens_hsa004600.80829617
85Vitamin B6 metabolism_Homo sapiens_hsa007500.79956666
86Pertussis_Homo sapiens_hsa051330.79672883
87Starch and sucrose metabolism_Homo sapiens_hsa005000.79502337
88Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.70968223
89Intestinal immune network for IgA production_Homo sapiens_hsa046720.70691793
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.70649978
91Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69845108
92Vitamin digestion and absorption_Homo sapiens_hsa049770.65960675
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65124057
94Vibrio cholerae infection_Homo sapiens_hsa051100.64052996
95Butanoate metabolism_Homo sapiens_hsa006500.62116822
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60185315
97Arginine and proline metabolism_Homo sapiens_hsa003300.60167096
98Tyrosine metabolism_Homo sapiens_hsa003500.57010921
99RNA transport_Homo sapiens_hsa030130.56243096
100Sphingolipid metabolism_Homo sapiens_hsa006000.55151264
101Allograft rejection_Homo sapiens_hsa053300.54906314
102Autoimmune thyroid disease_Homo sapiens_hsa053200.50432366
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50170230
104Phenylalanine metabolism_Homo sapiens_hsa003600.49046836
105Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.48973871
106Mineral absorption_Homo sapiens_hsa049780.48719002
107Non-homologous end-joining_Homo sapiens_hsa034500.45760807
108Phagosome_Homo sapiens_hsa041450.43873066
109Hematopoietic cell lineage_Homo sapiens_hsa046400.43381212
110Toll-like receptor signaling pathway_Homo sapiens_hsa046200.42628164
111Bile secretion_Homo sapiens_hsa049760.40457166
112Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.40423037
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40170866
114Staphylococcus aureus infection_Homo sapiens_hsa051500.39909862
115Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38565333
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38323183
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36699894
118Steroid biosynthesis_Homo sapiens_hsa001000.36505715
119Tuberculosis_Homo sapiens_hsa051520.35599157
120Fanconi anemia pathway_Homo sapiens_hsa034600.34632010
121Herpes simplex infection_Homo sapiens_hsa051680.34391967
122Cell cycle_Homo sapiens_hsa041100.33749306
123Antigen processing and presentation_Homo sapiens_hsa046120.33548840
124Leishmaniasis_Homo sapiens_hsa051400.33352706
125Linoleic acid metabolism_Homo sapiens_hsa005910.32937992
126Type I diabetes mellitus_Homo sapiens_hsa049400.31051779
127Graft-versus-host disease_Homo sapiens_hsa053320.28725379

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