SEC22B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)8.96483741
2Golgi transport vesicle coating (GO:0048200)8.96483741
3signal peptide processing (GO:0006465)8.20822537
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)7.34432995
5protein retention in ER lumen (GO:0006621)6.72570117
6ER overload response (GO:0006983)6.34045560
7COPII vesicle coating (GO:0048208)5.21906750
8protein maturation by protein folding (GO:0022417)5.17176383
9retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)4.73132382
10cellular ketone body metabolic process (GO:0046950)4.62842657
11positive regulation of protein autophosphorylation (GO:0031954)4.52791545
12peptide hormone processing (GO:0016486)4.30201228
13ketone body metabolic process (GO:1902224)4.25591300
14cullin deneddylation (GO:0010388)4.22405084
15positive regulation of glycolytic process (GO:0045821)4.11985226
16regulation of type B pancreatic cell apoptotic process (GO:2000674)4.10039122
17sequestering of metal ion (GO:0051238)4.01295690
18protein deneddylation (GO:0000338)3.90997694
19nucleotide transmembrane transport (GO:1901679)3.87748208
20endocrine pancreas development (GO:0031018)3.84098897
21vesicle coating (GO:0006901)3.81697977
22GDP-mannose metabolic process (GO:0019673)3.79718047
23nucleotide-sugar biosynthetic process (GO:0009226)3.70320339
24inositol phosphate dephosphorylation (GO:0046855)3.64948277
25phosphorylated carbohydrate dephosphorylation (GO:0046838)3.64948277
26viral protein processing (GO:0019082)3.62223378
27water-soluble vitamin biosynthetic process (GO:0042364)3.57922864
28zinc ion transport (GO:0006829)3.53161862
29* ER to Golgi vesicle-mediated transport (GO:0006888)3.47763418
30polyol catabolic process (GO:0046174)3.40413086
31exocrine pancreas development (GO:0031017)3.39827721
32deoxyribose phosphate biosynthetic process (GO:0046385)3.37854003
332-deoxyribonucleotide biosynthetic process (GO:0009265)3.37854003
34protein N-linked glycosylation via asparagine (GO:0018279)3.35549335
35negative regulation of glycogen biosynthetic process (GO:0045719)3.34756358
36negative regulation of dendrite morphogenesis (GO:0050774)3.31063290
37positive regulation of actin filament depolymerization (GO:0030836)3.30685403
38platelet dense granule organization (GO:0060155)3.29876768
39peptidyl-asparagine modification (GO:0018196)3.26416477
40positive regulation of mitochondrial fission (GO:0090141)3.25127395
41xenobiotic catabolic process (GO:0042178)3.23470695
42nucleotide-sugar metabolic process (GO:0009225)3.21914749
43regulation of protein autophosphorylation (GO:0031952)3.21584677
44glandular epithelial cell differentiation (GO:0002067)3.21327979
45regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.20693869
46negative regulation of neurological system process (GO:0031645)3.20201587
47keratinocyte development (GO:0003334)3.20037558
48dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.19792405
49UDP-N-acetylglucosamine metabolic process (GO:0006047)3.18393433
50regulation of glucokinase activity (GO:0033131)3.10537065
51regulation of hexokinase activity (GO:1903299)3.10537065
52regulation of protein glycosylation (GO:0060049)3.08801410
53intra-Golgi vesicle-mediated transport (GO:0006891)3.08472104
54GMP metabolic process (GO:0046037)3.06688953
55protein complex biogenesis (GO:0070271)3.04826052
56positive regulation of glycoprotein biosynthetic process (GO:0010560)3.04771695
57purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.03645444
583-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.03645444
59regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.03381750
60protein N-linked glycosylation (GO:0006487)3.02519624
61chaperone-mediated protein folding (GO:0061077)3.01244076
62negative regulation of acute inflammatory response (GO:0002674)3.01099436
63activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.99523907
64keratan sulfate catabolic process (GO:0042340)2.98626811
65DNA deamination (GO:0045006)2.97467996
66nitric oxide mediated signal transduction (GO:0007263)2.96863156
67chondrocyte development (GO:0002063)2.96774983
68intraciliary transport (GO:0042073)2.96301075
69insulin secretion (GO:0030073)2.91674301
70positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.91038176
71response to pheromone (GO:0019236)2.90888557
72positive regulation of insulin secretion (GO:0032024)2.90752194
73inositol phosphate catabolic process (GO:0071545)2.90215681
74type B pancreatic cell development (GO:0003323)2.89542153
75prenylation (GO:0097354)2.88347323
76protein prenylation (GO:0018342)2.88347323
77parental behavior (GO:0060746)2.88266987
78branched-chain amino acid catabolic process (GO:0009083)2.85207640
79negative regulation of glycogen metabolic process (GO:0070874)2.85185108
80prostate gland growth (GO:0060736)2.84987170
81peptidyl-histidine modification (GO:0018202)2.83882019
82positive regulation of steroid hormone secretion (GO:2000833)2.83773207
83cytochrome complex assembly (GO:0017004)2.82758229
84mannosylation (GO:0097502)2.82109167
85respiratory chain complex IV assembly (GO:0008535)2.81646077
86cellular response to topologically incorrect protein (GO:0035967)2.81625467
87cellular response to unfolded protein (GO:0034620)2.81001356
88positive regulation of nuclease activity (GO:0032075)2.80899790
89S-adenosylmethionine metabolic process (GO:0046500)2.80281679
90negative regulation of protein oligomerization (GO:0032460)2.77983776
91kidney morphogenesis (GO:0060993)2.77365783
92cell redox homeostasis (GO:0045454)2.77356949
93ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.76687567
94transcytosis (GO:0045056)2.76682508
95regulation of insulin secretion (GO:0050796)2.75243622
96negative regulation of execution phase of apoptosis (GO:1900118)2.75162059
97positive regulation of glycoprotein metabolic process (GO:1903020)2.74828100
98negative regulation of protein autophosphorylation (GO:0031953)2.72761249
99inositol phosphate-mediated signaling (GO:0048016)2.72418931
100positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.71779679
101endoplasmic reticulum unfolded protein response (GO:0030968)2.70921842
102regulation of penile erection (GO:0060405)2.70060407
103preassembly of GPI anchor in ER membrane (GO:0016254)2.69817345
104positive regulation of peptide hormone secretion (GO:0090277)2.69122173
105negative regulation of gluconeogenesis (GO:0045721)2.69065471
106ER-nucleus signaling pathway (GO:0006984)2.68794282
107positive regulation of amino acid transport (GO:0051957)2.68116172
108lactate metabolic process (GO:0006089)2.68020350
109regulation of acrosome reaction (GO:0060046)2.65776114
110L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.65227848
111negative regulation of complement activation (GO:0045916)2.65180622
112mitochondrial calcium ion transport (GO:0006851)2.64205187
113regulation of B cell apoptotic process (GO:0002902)2.63535839
114regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.62189906
115interleukin-1-mediated signaling pathway (GO:0070498)2.61527965
116nucleoside diphosphate catabolic process (GO:0009134)2.60077925
117positive regulation of meiosis (GO:0045836)2.59602064
118magnesium ion transport (GO:0015693)2.59047053
119C-terminal protein lipidation (GO:0006501)2.58875974
120eosinophil chemotaxis (GO:0048245)2.58628978
121proteasome assembly (GO:0043248)2.57995867
122transferrin transport (GO:0033572)2.57893277
123protein peptidyl-prolyl isomerization (GO:0000413)2.57873712
124zinc ion transmembrane transport (GO:0071577)2.56903929
125positive regulation of peptide secretion (GO:0002793)2.56659577
126dopamine transport (GO:0015872)2.56541564
127cellular response to zinc ion (GO:0071294)2.55494951
128mitochondrial respiratory chain complex assembly (GO:0033108)2.55367685
129protein targeting to Golgi (GO:0000042)2.55174083
130presynaptic membrane assembly (GO:0097105)2.54873094
131antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.54728431
132regulation of nuclease activity (GO:0032069)2.54703176
133deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.52799755
134regulation of peptide hormone secretion (GO:0090276)2.51913643
135protein-cofactor linkage (GO:0018065)2.51663821
136detection of calcium ion (GO:0005513)2.50930335
137zinc ion homeostasis (GO:0055069)2.50545576
138urinary tract smooth muscle contraction (GO:0014848)2.49374788
139ferric iron transport (GO:0015682)2.49086825
140trivalent inorganic cation transport (GO:0072512)2.49086825
141mitochondrial respiratory chain complex I assembly (GO:0032981)2.48824186
142NADH dehydrogenase complex assembly (GO:0010257)2.48824186
143mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.48824186
144establishment of protein localization to Golgi (GO:0072600)2.48643270
145regulation of peptide secretion (GO:0002791)2.47300749
146positive regulation of calcium ion import (GO:0090280)2.46839275
147protein localization to Golgi apparatus (GO:0034067)2.46533082
148negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.46332792
149regulation of Rac protein signal transduction (GO:0035020)2.46175793
150virion assembly (GO:0019068)2.44148965
151glandular epithelial cell development (GO:0002068)2.43022201
152negative regulation of hormone biosynthetic process (GO:0032353)2.42592260
153retinol metabolic process (GO:0042572)2.42326837
154regulation of hormone secretion (GO:0046883)2.42273620
155maintenance of protein localization in organelle (GO:0072595)2.42272245
156glycolipid catabolic process (GO:0019377)2.41411968
157negative regulation of protein activation cascade (GO:2000258)2.40992754
158response to endoplasmic reticulum stress (GO:0034976)2.40575158
159positive regulation of meiotic cell cycle (GO:0051446)2.40082712
160coenzyme catabolic process (GO:0009109)2.39450636
161glycoside metabolic process (GO:0016137)2.38708044
162peptide metabolic process (GO:0006518)2.37994557
163cellular zinc ion homeostasis (GO:0006882)2.37790163
164regulation of autophagic vacuole assembly (GO:2000785)2.36927299
165lipid particle organization (GO:0034389)2.35488021
166regulation of neurotransmitter uptake (GO:0051580)2.31352184
167axoneme assembly (GO:0035082)2.31291619
168C-terminal protein amino acid modification (GO:0018410)2.27809921
169tryptophan catabolic process (GO:0006569)2.26250757
170indole-containing compound catabolic process (GO:0042436)2.26250757
171indolalkylamine catabolic process (GO:0046218)2.26250757
172retrograde transport, vesicle recycling within Golgi (GO:0000301)2.25514223
173pancreas development (GO:0031016)2.25098291
174righting reflex (GO:0060013)2.23594361
175positive regulation of macroautophagy (GO:0016239)2.22747315
176L-fucose metabolic process (GO:0042354)2.21152063
177L-fucose catabolic process (GO:0042355)2.21152063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.89970138
2PDX1_19855005_ChIP-ChIP_MIN6_Mouse3.49308687
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.28691711
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.24045507
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.11093368
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.86887083
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.61114357
8GBX2_23144817_ChIP-Seq_PC3_Human2.56886305
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.56354715
10ZNF274_21170338_ChIP-Seq_K562_Hela2.53433175
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.39667452
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.31354191
13PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.26392209
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.10598835
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.09178454
16DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.08415214
17ELK1_19687146_ChIP-ChIP_HELA_Human2.06668974
18EST1_17652178_ChIP-ChIP_JURKAT_Human1.96896858
19FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.95887477
20* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.93624773
21WT1_19549856_ChIP-ChIP_CCG9911_Human1.90958317
22SRF_21415370_ChIP-Seq_HL-1_Mouse1.90803219
23FLI1_27457419_Chip-Seq_LIVER_Mouse1.82243711
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.81664322
25FUS_26573619_Chip-Seq_HEK293_Human1.81511143
26VDR_22108803_ChIP-Seq_LS180_Human1.80245999
27BMI1_23680149_ChIP-Seq_NPCS_Mouse1.71742697
28IGF1R_20145208_ChIP-Seq_DFB_Human1.71647639
29P300_19829295_ChIP-Seq_ESCs_Human1.71644226
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.71161573
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65636084
32NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.64805038
33NRF2_20460467_ChIP-Seq_MEFs_Mouse1.64805038
34FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.64135605
35TRIM28_21343339_ChIP-Seq_HEK293_Human1.63024929
36BCAT_22108803_ChIP-Seq_LS180_Human1.60271853
37PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.60125367
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.56597583
39CDX2_22108803_ChIP-Seq_LS180_Human1.56265582
40TAF15_26573619_Chip-Seq_HEK293_Human1.55637922
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50653343
42TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46611193
43STAT3_18555785_Chip-Seq_ESCs_Mouse1.44506669
44CREB1_15753290_ChIP-ChIP_HEK293T_Human1.44174583
45AR_25329375_ChIP-Seq_VCAP_Human1.41198351
46EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.40070299
47CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.39766273
48P53_22387025_ChIP-Seq_ESCs_Mouse1.38715073
49EGR1_23403033_ChIP-Seq_LIVER_Mouse1.37869671
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36238380
51STAT3_23295773_ChIP-Seq_U87_Human1.34304404
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.32631419
53GATA1_22025678_ChIP-Seq_K562_Human1.32367183
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32363396
55CBP_20019798_ChIP-Seq_JUKART_Human1.32363396
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32309785
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.32075303
58REST_19997604_ChIP-ChIP_NEURONS_Mouse1.31854362
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.30397321
60BRD4_25478319_ChIP-Seq_HGPS_Human1.29695655
61FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.29497270
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.29319040
63FOXM1_26456572_ChIP-Seq_MCF-7_Human1.29138599
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28425066
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27768435
66* CJUN_26792858_Chip-Seq_BT549_Human1.26979474
67* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26467204
68EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25321518
69TCF4_22108803_ChIP-Seq_LS180_Human1.23885396
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.23489759
71PADI4_21655091_ChIP-ChIP_MCF-7_Human1.23403315
72TP53_22573176_ChIP-Seq_HFKS_Human1.22814717
73* SMAD4_21799915_ChIP-Seq_A2780_Human1.22632758
74NR3C1_21868756_ChIP-Seq_MCF10A_Human1.22267581
75NMYC_18555785_Chip-Seq_ESCs_Mouse1.21801586
76PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21577361
77HOXB4_20404135_ChIP-ChIP_EML_Mouse1.21051355
78SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.17948781
79OCT4_21477851_ChIP-Seq_ESCs_Mouse1.17708780
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17545740
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.17013430
82TCF4_23295773_ChIP-Seq_U87_Human1.16978127
83E2F1_18555785_Chip-Seq_ESCs_Mouse1.16559556
84HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.16200013
85DCP1A_22483619_ChIP-Seq_HELA_Human1.15049445
86* VDR_23849224_ChIP-Seq_CD4+_Human1.15047269
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14818638
88SUZ12_18555785_Chip-Seq_ESCs_Mouse1.14516548
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.14452645
90ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14210312
91* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14159259
92SOX2_18555785_Chip-Seq_ESCs_Mouse1.13134200
93SMAD4_21741376_ChIP-Seq_EPCs_Human1.12153146
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11752530
95KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11236706
96CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.10896931
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10884546
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10325654
99CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.10144438
100FOXA1_25329375_ChIP-Seq_VCAP_Human1.10012125
101FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10012125
102TAL1_26923725_Chip-Seq_HPCs_Mouse1.09385866
103FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09275382
104IRF8_22096565_ChIP-ChIP_GC-B_Human1.09107156
105E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.08771599
106AR_20517297_ChIP-Seq_VCAP_Human1.08518837
107P300_18555785_Chip-Seq_ESCs_Mouse1.08312427
108OCT4_18555785_Chip-Seq_ESCs_Mouse1.08260593
109MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08005356
110NFE2_27457419_Chip-Seq_LIVER_Mouse1.08005164
111* PHF8_20622853_ChIP-Seq_HELA_Human1.06427444
112CTCF_18555785_Chip-Seq_ESCs_Mouse1.06153404
113* ER_23166858_ChIP-Seq_MCF-7_Human1.06094548
114SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05971373
115NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.05469241
116PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05259726
117JUN_21703547_ChIP-Seq_K562_Human1.05164744
118EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04579546
119SOX2_20726797_ChIP-Seq_SW620_Human1.04185479
120* CMYC_18555785_Chip-Seq_ESCs_Mouse1.02809874
121EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.02787729
122GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02701805
123ERG_20887958_ChIP-Seq_HPC-7_Mouse1.00809968
124RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00533819
125NANOG_19829295_ChIP-Seq_ESCs_Human0.99971464
126SOX2_19829295_ChIP-Seq_ESCs_Human0.99971464
127CRX_20693478_ChIP-Seq_RETINA_Mouse0.99841432
128* ETS1_20019798_ChIP-Seq_JURKAT_Human0.99453899
129SMAD1_18555785_Chip-Seq_ESCs_Mouse0.99217291
130SMAD_19615063_ChIP-ChIP_OVARY_Human0.97749865
131PU1_27457419_Chip-Seq_LIVER_Mouse0.97535584
132PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.96615016
133RNF2_27304074_Chip-Seq_NSC_Mouse0.95603577
134FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95286604
135* PIAS1_25552417_ChIP-Seq_VCAP_Human0.95093776
136EED_16625203_ChIP-ChIP_MESCs_Mouse0.93649608
137EWS_26573619_Chip-Seq_HEK293_Human0.93303775
138* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.92774073
139CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.92692328
140THAP11_20581084_ChIP-Seq_MESCs_Mouse0.91429209
141* GABP_19822575_ChIP-Seq_HepG2_Human0.91053562
142TP53_18474530_ChIP-ChIP_U2OS_Human0.90909143

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001986_abnormal_taste_sensitivity3.95300584
2MP0002877_abnormal_melanocyte_morpholog3.80942542
3MP0003195_calcinosis3.60223613
4MP0010234_abnormal_vibrissa_follicle3.58239887
5MP0009780_abnormal_chondrocyte_physiolo3.44494444
6MP0003183_abnormal_peptide_metabolism3.41606032
7MP0000013_abnormal_adipose_tissue3.19476001
8MP0010386_abnormal_urinary_bladder3.14198903
9MP0005379_endocrine/exocrine_gland_phen3.14014666
10MP0002876_abnormal_thyroid_physiology2.77870168
11MP0003122_maternal_imprinting2.74780221
12MP0006054_spinal_hemorrhage2.70951213
13MP0005646_abnormal_pituitary_gland2.52485777
14MP0004043_abnormal_pH_regulation2.48502463
15MP0002693_abnormal_pancreas_physiology2.47473170
16MP0005084_abnormal_gallbladder_morpholo2.43642611
17MP0005360_urolithiasis2.41841805
18MP0005503_abnormal_tendon_morphology2.39651416
19MP0001944_abnormal_pancreas_morphology2.35326786
20MP0000569_abnormal_digit_pigmentation2.29934232
21MP0002163_abnormal_gland_morphology2.28935735
22MP0002254_reproductive_system_inflammat2.26562455
23MP0005220_abnormal_exocrine_pancreas2.24278438
24MP0002909_abnormal_adrenal_gland2.18369831
25MP0002837_dystrophic_cardiac_calcinosis2.17709957
26MP0001188_hyperpigmentation2.12897929
27MP0009697_abnormal_copulation2.12767849
28MP0005645_abnormal_hypothalamus_physiol2.12761687
29MP0004134_abnormal_chest_morphology2.10827957
30MP0001542_abnormal_bone_strength2.08159993
31MP0002638_abnormal_pupillary_reflex2.04080636
32MP0003950_abnormal_plasma_membrane1.84319219
33MP0000678_abnormal_parathyroid_gland1.82187878
34MP0000681_abnormal_thyroid_gland1.78253024
35MP0001756_abnormal_urination1.77337441
36MP0005332_abnormal_amino_acid1.72233426
37MP0006276_abnormal_autonomic_nervous1.70528563
38MP0000372_irregular_coat_pigmentation1.67794349
39MP0000427_abnormal_hair_cycle1.64557818
40MP0002090_abnormal_vision1.62804557
41MP0002102_abnormal_ear_morphology1.62644034
42MP0003283_abnormal_digestive_organ1.59937643
43MP0002751_abnormal_autonomic_nervous1.59874933
44MP0002735_abnormal_chemical_nociception1.54167596
45MP0010329_abnormal_lipoprotein_level1.53182195
46MP0008877_abnormal_DNA_methylation1.52551750
47MP0003252_abnormal_bile_duct1.49820993
48MP0001661_extended_life_span1.48374157
49MP0000163_abnormal_cartilage_morphology1.48123873
50MP0009250_abnormal_appendicular_skeleto1.46959806
51MP0002896_abnormal_bone_mineralization1.45546421
52MP0002166_altered_tumor_susceptibility1.43082603
53MP0005551_abnormal_eye_electrophysiolog1.41193240
54MP0002139_abnormal_hepatobiliary_system1.38321885
55MP0008438_abnormal_cutaneous_collagen1.38006357
56MP0005171_absent_coat_pigmentation1.35591486
57MP0003806_abnormal_nucleotide_metabolis1.33786842
58MP0009046_muscle_twitch1.32825359
59MP0001764_abnormal_homeostasis1.31973649
60MP0010352_gastrointestinal_tract_polyps1.31896382
61MP0002933_joint_inflammation1.31867174
62MP0002938_white_spotting1.31048843
63MP0004782_abnormal_surfactant_physiolog1.30923018
64MP0005174_abnormal_tail_pigmentation1.30236830
65MP0005408_hypopigmentation1.24894471
66MP0001270_distended_abdomen1.21965230
67MP0002115_abnormal_skeleton_extremities1.20064799
68MP0002078_abnormal_glucose_homeostasis1.19387656
69MP0002168_other_aberrant_phenotype1.18943736
70MP0003795_abnormal_bone_structure1.18881313
71MP0005075_abnormal_melanosome_morpholog1.16406355
72MP0005508_abnormal_skeleton_morphology1.16141825
73MP0002734_abnormal_mechanical_nocicepti1.16072639
74MP0003172_abnormal_lysosome_physiology1.15744839
75MP0001919_abnormal_reproductive_system1.14858805
76MP0010678_abnormal_skin_adnexa1.12877453
77MP0001984_abnormal_olfaction1.12714617
78MP0004019_abnormal_vitamin_homeostasis1.10876320
79MP0000631_abnormal_neuroendocrine_gland1.10250463
80MP0003123_paternal_imprinting1.09494679
81MP0002160_abnormal_reproductive_system1.09245513
82MP0003787_abnormal_imprinting1.09209596
83MP0006036_abnormal_mitochondrial_physio1.08892595
84MP0005390_skeleton_phenotype1.07611734
85MP0006072_abnormal_retinal_apoptosis1.06493039
86MP0003724_increased_susceptibility_to1.05407917
87MP0003786_premature_aging1.05223389
88MP0003943_abnormal_hepatobiliary_system1.01363101
89MP0002736_abnormal_nociception_after1.00437228
90MP0001299_abnormal_eye_distance/1.00011496
91MP0001501_abnormal_sleep_pattern0.99580695
92MP0000538_abnormal_urinary_bladder0.99366020
93MP0000639_abnormal_adrenal_gland0.98197656
94MP0005389_reproductive_system_phenotype0.97818699
95MP0008775_abnormal_heart_ventricle0.97579656
96MP0002006_tumorigenesis0.97039386
97MP0002113_abnormal_skeleton_development0.96047289
98MP0000566_synostosis0.95392292
99MP0001879_abnormal_lymphatic_vessel0.95238276
100MP0000015_abnormal_ear_pigmentation0.93707358
101MP0002928_abnormal_bile_duct0.91058594
102MP0000230_abnormal_systemic_arterial0.90474913
103MP0003121_genomic_imprinting0.89605080
104MP0003045_fibrosis0.89442362
105MP0006292_abnormal_olfactory_placode0.89085107
106MP0001533_abnormal_skeleton_physiology0.88932368
107MP0008872_abnormal_physiological_respon0.88814981
108MP0009643_abnormal_urine_homeostasis0.87677880
109MP0008875_abnormal_xenobiotic_pharmacok0.86531494
110MP0003953_abnormal_hormone_level0.86429830
111MP0004270_analgesia0.86379265
112MP0005085_abnormal_gallbladder_physiolo0.84860622
113MP0003942_abnormal_urinary_system0.84488323
114MP0002177_abnormal_outer_ear0.83625480
115MP0000049_abnormal_middle_ear0.83356868
116MP0006082_CNS_inflammation0.83297681
117MP0004264_abnormal_extraembryonic_tissu0.83019906
118MP0004215_abnormal_myocardial_fiber0.82720785
119MP0001905_abnormal_dopamine_level0.81905769
120MP0008789_abnormal_olfactory_epithelium0.80926731
121MP0005395_other_phenotype0.80407470
122MP0003011_delayed_dark_adaptation0.80257501
123MP0000003_abnormal_adipose_tissue0.80053771
124MP0002295_abnormal_pulmonary_circulatio0.79597079
125MP0005367_renal/urinary_system_phenotyp0.79019122
126MP0000516_abnormal_urinary_system0.79019122
127MP0004147_increased_porphyrin_level0.78916149
128MP0005257_abnormal_intraocular_pressure0.77941287
129MP0003633_abnormal_nervous_system0.77674114
130MP0003186_abnormal_redox_activity0.77176919
131MP0002998_abnormal_bone_remodeling0.76025105
132MP0002009_preneoplasia0.74806754
133MP0003959_abnormal_lean_body0.74198615
134MP0004484_altered_response_of0.74155389
135MP0005365_abnormal_bile_salt0.73526045
136MP0000613_abnormal_salivary_gland0.73274541
137MP0005636_abnormal_mineral_homeostasis0.72643499
138MP0005253_abnormal_eye_physiology0.71355028
139MP0002109_abnormal_limb_morphology0.71128981
140MP0002118_abnormal_lipid_homeostasis0.69782729
141MP0009384_cardiac_valve_regurgitation0.69581761
142MP0003868_abnormal_feces_composition0.69221984
143MP0000371_diluted_coat_color0.68854803
144MP0001765_abnormal_ion_homeostasis0.68226337
145MP0002282_abnormal_trachea_morphology0.65860372
146MP0001177_atelectasis0.65851327
147MP0005647_abnormal_sex_gland0.65635423
148MP0001664_abnormal_digestion0.65567673
149MP0005410_abnormal_fertilization0.64848651
150MP0000647_abnormal_sebaceous_gland0.58609701

Predicted human phenotypes

RankGene SetZ-score
1Irregular epiphyses (HP:0010582)4.57242764
2Epiphyseal dysplasia (HP:0002656)4.56536522
3Hypothermia (HP:0002045)4.52685312
4Ketoacidosis (HP:0001993)3.93691757
5Flat capital femoral epiphysis (HP:0003370)3.90202480
6Irregular vertebral endplates (HP:0003301)3.61526935
7Vitreoretinal degeneration (HP:0000655)3.59864227
8Symptomatic seizures (HP:0011145)3.49833597
9Abnormality of the vertebral endplates (HP:0005106)3.42892768
10Tongue fasciculations (HP:0001308)3.31834565
11Conjunctival hamartoma (HP:0100780)3.22713275
12Hematochezia (HP:0002573)3.22679701
13Abnormal tarsal ossification (HP:0008369)3.16973339
14Hypoglycemic seizures (HP:0002173)3.16964358
15Type I transferrin isoform profile (HP:0003642)3.14819113
16Hamartoma of the eye (HP:0010568)3.13395801
17Hyperinsulinemic hypoglycemia (HP:0000825)3.11860477
18Pheochromocytoma (HP:0002666)3.07530636
19Large for gestational age (HP:0001520)3.05755554
20Metaphyseal dysplasia (HP:0100255)3.05589668
21Neuroendocrine neoplasm (HP:0100634)2.97024961
22Thyroiditis (HP:0100646)2.93885349
23Renal cortical cysts (HP:0000803)2.89699716
24Beaking of vertebral bodies (HP:0004568)2.89086572
25Abnormality of aromatic amino acid family metabolism (HP:0004338)2.88182693
26Neoplasm of the adrenal cortex (HP:0100641)2.87300128
27Abnormality of vitamin B metabolism (HP:0004340)2.85982170
28Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.85160067
29Small epiphyses (HP:0010585)2.82929450
30Abnormal glycosylation (HP:0012345)2.81777694
31Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.81777694
32Abnormal protein N-linked glycosylation (HP:0012347)2.81777694
33Abnormal protein glycosylation (HP:0012346)2.81777694
34Acute necrotizing encephalopathy (HP:0006965)2.80421679
35Enlarged penis (HP:0000040)2.78865339
36Medial flaring of the eyebrow (HP:0010747)2.76501582
37Abnormal pancreas size (HP:0012094)2.75796406
38Disproportionate short-trunk short stature (HP:0003521)2.73962798
39Muscle fibrillation (HP:0010546)2.72861085
40Cutaneous melanoma (HP:0012056)2.70658792
41Abnormality of the renal cortex (HP:0011035)2.68135791
42Cupped ribs (HP:0000887)2.67096391
43Methylmalonic acidemia (HP:0002912)2.65476741
44Delayed epiphyseal ossification (HP:0002663)2.65035064
45Hypomagnesemia (HP:0002917)2.62980054
46Abnormal mitochondria in muscle tissue (HP:0008316)2.61658519
47Metaphyseal irregularity (HP:0003025)2.59231540
48Abnormality of the intrinsic pathway (HP:0010989)2.57793217
49Delayed gross motor development (HP:0002194)2.56864354
50Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.56542144
51Abnormality of femoral epiphyses (HP:0006499)2.56542144
52Increased CSF protein (HP:0002922)2.55574355
53Ketosis (HP:0001946)2.54427076
54Pancreatic cysts (HP:0001737)2.53804216
55Insulin-resistant diabetes mellitus (HP:0000831)2.53105673
56Conjugated hyperbilirubinemia (HP:0002908)2.52656350
57Thoracolumbar scoliosis (HP:0002944)2.50560100
58Abnormal foot bone ossification (HP:0010675)2.48887427
59Nephrogenic diabetes insipidus (HP:0009806)2.48749049
60Hypoglycemic coma (HP:0001325)2.48543812
61Hyperglycemia (HP:0003074)2.48094295
62Abnormality of the femoral head (HP:0003368)2.47688717
63Abnormality of the epiphysis of the femoral head (HP:0010574)2.45593610
64Congenital primary aphakia (HP:0007707)2.45212213
65Hypokinesia (HP:0002375)2.44793941
66Genu varum (HP:0002970)2.43534127
67True hermaphroditism (HP:0010459)2.43455547
68Generalized aminoaciduria (HP:0002909)2.42949709
69Abnormality of calcium-phosphate metabolism (HP:0100530)2.42463377
70Progressive macrocephaly (HP:0004481)2.41659706
71Intestinal atresia (HP:0011100)2.41211955
72Abnormality of incisor morphology (HP:0011063)2.40775524
73Neoplasm of the adrenal gland (HP:0100631)2.39163112
74Albinism (HP:0001022)2.39086266
75Vertebral compression fractures (HP:0002953)2.38345689
76Abnormal albumin level (HP:0012116)2.35625815
77Hypoalbuminemia (HP:0003073)2.35625815
78Gait imbalance (HP:0002141)2.33825430
79Furrowed tongue (HP:0000221)2.30894567
80Osteoarthritis (HP:0002758)2.30717976
81Acute encephalopathy (HP:0006846)2.22615030
82Flattened epiphyses (HP:0003071)2.22122005
83Mitochondrial inheritance (HP:0001427)2.19608995
84Osteomalacia (HP:0002749)2.19083621
85Proximal tubulopathy (HP:0000114)2.18281375
86Methylmalonic aciduria (HP:0012120)2.18258852
87Pancreatic fibrosis (HP:0100732)2.18244068
88Cervical subluxation (HP:0003308)2.16793645
89Hemiparesis (HP:0001269)2.16563617
90Congenital sensorineural hearing impairment (HP:0008527)2.15258062
91Congenital stationary night blindness (HP:0007642)2.14135719
92Hepatoblastoma (HP:0002884)2.13738025
93Reduced antithrombin III activity (HP:0001976)2.13408667
94Abnormality of the ischium (HP:0003174)2.13193211
95Cardiovascular calcification (HP:0011915)2.10639135
96Arthropathy (HP:0003040)2.09801943
97Vascular calcification (HP:0004934)2.07677675
98Absent eyebrow (HP:0002223)2.07333560
99Abnormality of vitamin metabolism (HP:0100508)2.06379345
100Hypobetalipoproteinemia (HP:0003563)2.04814888
101Testicular neoplasm (HP:0010788)2.03694930
102Prominent metopic ridge (HP:0005487)2.02684890
103Nephronophthisis (HP:0000090)2.02683406
104Bone cyst (HP:0012062)2.01846151
105Vacuolated lymphocytes (HP:0001922)2.01235827
106Pancreatic islet-cell hyperplasia (HP:0004510)1.98958694
107Molar tooth sign on MRI (HP:0002419)1.97260707
108Abnormality of midbrain morphology (HP:0002418)1.97260707
109Hypoplastic ischia (HP:0003175)1.97019614
110Abnormality of dentin (HP:0010299)1.97000749
111Abnormal hair whorl (HP:0010721)1.96782117
112Polydipsia (HP:0001959)1.96225234
113Abnormal drinking behavior (HP:0030082)1.96225234
114Short femoral neck (HP:0100864)1.95877676
115Platyspondyly (HP:0000926)1.95842648
116Enlarged epiphyses (HP:0010580)1.95407191
117Absent epiphyses (HP:0010577)1.94678633
118Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.94678633
119Abnormality of the fovea (HP:0000493)1.94004222
120Oligomenorrhea (HP:0000876)1.93540789
121Barrel-shaped chest (HP:0001552)1.93263154
122Gaze-evoked nystagmus (HP:0000640)1.93096179
123Hepatic necrosis (HP:0002605)1.92917578
124Progressive inability to walk (HP:0002505)1.92252811
125Decreased circulating renin level (HP:0003351)1.92094113
126Meningioma (HP:0002858)1.91922817
127Hypoplasia of the odontoid process (HP:0003311)1.91881888
128Increased CSF lactate (HP:0002490)1.91709507
129Muscular hypotonia of the trunk (HP:0008936)1.90796820
130Aqueductal stenosis (HP:0002410)1.88710701
131Mild short stature (HP:0003502)1.88679274
132Abnormality of magnesium homeostasis (HP:0004921)1.87908413
133Abnormality of endocrine pancreas physiology (HP:0012093)1.87715726
134Abnormality of the pancreatic islet cells (HP:0006476)1.87715726
135Protuberant abdomen (HP:0001538)1.87617886
136Abnormality of the metopic suture (HP:0005556)1.82774492
137Aplasia/Hypoplasia of the lens (HP:0008063)1.82569116
138Enlarged kidneys (HP:0000105)1.82328197
139Dysautonomia (HP:0002459)1.80907128
140EEG with generalized epileptiform discharges (HP:0011198)1.80456158
141Hypoproteinemia (HP:0003075)1.79707997
142Alveolar cell carcinoma (HP:0006519)1.79352968
143Diminished movement (HP:0002374)1.78845299
144Patent foramen ovale (HP:0001655)1.78785965
145Sensory axonal neuropathy (HP:0003390)1.78466567
146Type I diabetes mellitus (HP:0100651)1.78420488
147Abnormality of urine glucose concentration (HP:0011016)1.78293185
148Glycosuria (HP:0003076)1.78293185
149Abnormality of the wing of the ilium (HP:0011867)1.78233718
150Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.78170198
151Hypoplasia of the fovea (HP:0007750)1.77773674
152Aplasia/Hypoplasia of the fovea (HP:0008060)1.77773674
153Abnormality of the renal medulla (HP:0100957)1.77280386
154Ovoid vertebral bodies (HP:0003300)1.76386431
155Late onset (HP:0003584)1.76364075
156Abnormality of aspartate family amino acid metabolism (HP:0010899)1.75863710
157Patchy hypopigmentation of hair (HP:0011365)1.74798504
158Biconcave vertebral bodies (HP:0004586)1.73705061
159Fair hair (HP:0002286)1.73605762
160Hypoplasia of the pons (HP:0012110)1.73138967
161Abnormality of the vitamin B12 metabolism (HP:0004341)1.73069469
162Epileptiform EEG discharges (HP:0011182)1.73065353
163Absent rod-and cone-mediated responses on ERG (HP:0007688)1.72827606
164Flared iliac wings (HP:0002869)1.72438059
165Absent eyelashes (HP:0000561)1.72264626
166Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.72103066
167Asymmetry of the thorax (HP:0001555)1.71877045
168Hypsarrhythmia (HP:0002521)1.71594247
169Median cleft lip (HP:0000161)1.70867812

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.39025621
2FRK3.42527810
3AKT33.23968677
4INSRR3.21672241
5ERBB33.17023975
6FGFR22.97524155
7SIK32.88450217
8ACVR1B2.53333155
9TRIM282.48044699
10MAP4K22.37251190
11BMPR22.30174281
12GRK12.26983936
13MAPK152.18491282
14MAP3K32.12862212
15EIF2AK32.07637400
16STK162.02900196
17PAK31.91754053
18PASK1.87290007
19ZAK1.74905931
20MAP3K121.67879430
21MAP3K141.65625281
22BMPR1B1.64272979
23STK38L1.57367984
24PINK11.57342871
25PLK21.55631285
26BCR1.55210946
27SGK21.53755921
28NME11.53017620
29MAP3K21.50452580
30BRAF1.49990280
31PRPF4B1.48938220
32MAP2K71.46551799
33NEK91.45690979
34NEK61.44498761
35CDK81.44157421
36STK241.42916359
37FGFR31.41552002
38MUSK1.38892905
39PHKG11.34588762
40PHKG21.34588762
41CAMKK21.34135293
42IRAK31.28657786
43WNK31.22682617
44BRSK21.20490899
45MAPK131.20202903
46TNIK1.13724875
47STK31.13714150
48STK391.11581143
49PIM21.09300140
50IRAK41.09241786
51MST41.06713331
52CSNK1G11.04485288
53OXSR11.04383498
54EPHA31.04342227
55SGK4941.04012533
56SGK2231.04012533
57MYLK1.01517418
58PIK3CA1.01071922
59TAOK31.00953688
60VRK11.00917120
61MKNK20.98784054
62PRKD30.96580304
63YES10.96524404
64PIK3CG0.95626341
65EIF2AK10.95379168
66CCNB10.92409623
67NUAK10.89608865
68CSNK1G30.88926593
69LIMK10.88903023
70PBK0.87826890
71PRKG20.87188645
72BCKDK0.86223136
73PRKCE0.84669947
74DAPK20.83199160
75FLT30.80929456
76HIPK20.80921468
77IRAK10.80330164
78ADRBK20.79520023
79PTK2B0.79092943
80TESK10.78818788
81CSNK1G20.78580479
82TGFBR10.77361326
83TEC0.76763815
84ARAF0.71741241
85CDC42BPA0.70565155
86PLK30.69326231
87ERN10.68871099
88MAP3K40.68517990
89RPS6KB10.68229887
90FER0.63751125
91CSNK1A1L0.62660886
92MAP2K60.62040891
93MINK10.60413965
94NTRK30.60379168
95PRKCI0.59647298
96ROCK10.58492390
97WNK40.58162358
98SGK30.57292788
99RPS6KA40.56549948
100MAP2K10.53931150
101TGFBR20.53136574
102PDK20.52888124
103BRSK10.51959969
104NLK0.51831757
105GRK70.51337497
106ERBB40.51300079
107RPS6KA20.50824728
108TSSK60.49267422
109ADRBK10.49141259
110MKNK10.48388354
111JAK10.44385204
112TYK20.43257283
113MAPKAPK30.42715000
114TRPM70.41914145
115PRKCH0.41797801
116CAMK2D0.41781316
117PNCK0.41389463
118DAPK10.41117626
119PTK20.39668206
120UHMK10.39095585
121PRKAA20.37107381
122ABL10.36951351
123CSNK1A10.36200219
124IRAK20.35806163
125PRKCG0.35166562
126CDK30.34739325
127GSK3A0.34470801
128TXK0.32169984
129IKBKB0.31659516
130CAMK2B0.29846787
131GRK50.29820372
132DDR20.28728732
133CAMK2A0.28643398
134DYRK1A0.28096289
135PRKAA10.28002419
136PRKG10.27855752
137RPS6KA60.27771834
138MARK30.27093897
139PKN20.27091652
140MAPKAPK50.26535737
141ILK0.24787580
142NEK10.24535603
143TNK20.23906388
144EIF2AK20.23888300
145FGFR10.23560199

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030607.73261591
2Maturity onset diabetes of the young_Homo sapiens_hsa049505.63023609
3Sulfur metabolism_Homo sapiens_hsa009203.45956194
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.19124386
5Vibrio cholerae infection_Homo sapiens_hsa051103.16741994
6Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.00888173
7Butanoate metabolism_Homo sapiens_hsa006502.73966040
8Vitamin B6 metabolism_Homo sapiens_hsa007502.73917077
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.55446554
10* SNARE interactions in vesicular transport_Homo sapiens_hsa041302.32826222
11Proteasome_Homo sapiens_hsa030502.16829608
12Collecting duct acid secretion_Homo sapiens_hsa049662.16066048
13Oxidative phosphorylation_Homo sapiens_hsa001902.11023740
14Propanoate metabolism_Homo sapiens_hsa006402.10518298
15Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.06589127
16N-Glycan biosynthesis_Homo sapiens_hsa005102.06302700
17Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.05239875
18Insulin secretion_Homo sapiens_hsa049111.80843183
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.75184849
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.72534004
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.67791403
22Folate biosynthesis_Homo sapiens_hsa007901.64032305
23Primary bile acid biosynthesis_Homo sapiens_hsa001201.61054988
24Phototransduction_Homo sapiens_hsa047441.59559819
25Synaptic vesicle cycle_Homo sapiens_hsa047211.57018894
26Tryptophan metabolism_Homo sapiens_hsa003801.53013031
27Type I diabetes mellitus_Homo sapiens_hsa049401.52466195
28Regulation of autophagy_Homo sapiens_hsa041401.51927963
29Parkinsons disease_Homo sapiens_hsa050121.41677966
30Galactose metabolism_Homo sapiens_hsa000521.33908358
31Nitrogen metabolism_Homo sapiens_hsa009101.30920823
32* Phagosome_Homo sapiens_hsa041451.29405160
33Mineral absorption_Homo sapiens_hsa049781.29310854
34Rheumatoid arthritis_Homo sapiens_hsa053231.22074031
35Ether lipid metabolism_Homo sapiens_hsa005651.17236484
36Other glycan degradation_Homo sapiens_hsa005111.16962905
37Protein digestion and absorption_Homo sapiens_hsa049741.06619405
38Fatty acid metabolism_Homo sapiens_hsa012121.06512519
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05190796
40Caffeine metabolism_Homo sapiens_hsa002321.05181735
41Alzheimers disease_Homo sapiens_hsa050101.03172844
42Lysosome_Homo sapiens_hsa041421.00159682
43Fatty acid degradation_Homo sapiens_hsa000710.99611284
44Sphingolipid metabolism_Homo sapiens_hsa006000.99309634
45Huntingtons disease_Homo sapiens_hsa050160.95941426
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.93601248
47Selenocompound metabolism_Homo sapiens_hsa004500.92631251
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.92519574
49Circadian rhythm_Homo sapiens_hsa047100.86877823
50Chemical carcinogenesis_Homo sapiens_hsa052040.86418824
51Cocaine addiction_Homo sapiens_hsa050300.85750445
52Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.85662117
53beta-Alanine metabolism_Homo sapiens_hsa004100.84114790
54Basal transcription factors_Homo sapiens_hsa030220.83548631
55Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.83178660
56Linoleic acid metabolism_Homo sapiens_hsa005910.81996568
57Glutathione metabolism_Homo sapiens_hsa004800.80714126
58Fatty acid elongation_Homo sapiens_hsa000620.80430141
59alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.79202389
60ABC transporters_Homo sapiens_hsa020100.77279267
61Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76826995
62Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76720171
63Amphetamine addiction_Homo sapiens_hsa050310.76273718
64Serotonergic synapse_Homo sapiens_hsa047260.75297876
65Retinol metabolism_Homo sapiens_hsa008300.75252789
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.72608124
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71413228
68Taste transduction_Homo sapiens_hsa047420.70993018
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.70346742
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.70269172
71One carbon pool by folate_Homo sapiens_hsa006700.68319049
72Thyroid hormone synthesis_Homo sapiens_hsa049180.67759754
73Olfactory transduction_Homo sapiens_hsa047400.64989793
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64106776
75Arachidonic acid metabolism_Homo sapiens_hsa005900.62744801
76Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.62170195
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61577862
78Purine metabolism_Homo sapiens_hsa002300.61271345
79Starch and sucrose metabolism_Homo sapiens_hsa005000.61236696
80Ovarian steroidogenesis_Homo sapiens_hsa049130.60967997
81Renin secretion_Homo sapiens_hsa049240.60349549
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60153008
83Dopaminergic synapse_Homo sapiens_hsa047280.59621696
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56537983
85Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55841958
86Steroid biosynthesis_Homo sapiens_hsa001000.53330634
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51652537
88Pyrimidine metabolism_Homo sapiens_hsa002400.51440453
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49947607
90Thyroid cancer_Homo sapiens_hsa052160.48653525
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48379958
92Circadian entrainment_Homo sapiens_hsa047130.47921657
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47027639
94Metabolic pathways_Homo sapiens_hsa011000.46986028
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45435786
96Complement and coagulation cascades_Homo sapiens_hsa046100.45030769
97Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44686746
98Dorso-ventral axis formation_Homo sapiens_hsa043200.44514308
99Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44417686
100Pyruvate metabolism_Homo sapiens_hsa006200.42976052
101RNA degradation_Homo sapiens_hsa030180.42459504
102Non-homologous end-joining_Homo sapiens_hsa034500.38808364
103* Legionellosis_Homo sapiens_hsa051340.38526330
104Fructose and mannose metabolism_Homo sapiens_hsa000510.37742144
105Fat digestion and absorption_Homo sapiens_hsa049750.33314164
106GABAergic synapse_Homo sapiens_hsa047270.32265993
107Pancreatic secretion_Homo sapiens_hsa049720.32005309
108RNA polymerase_Homo sapiens_hsa030200.31398591
109Salivary secretion_Homo sapiens_hsa049700.31216769
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.30797475
111Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.30594919
112Antigen processing and presentation_Homo sapiens_hsa046120.29818264
113Homologous recombination_Homo sapiens_hsa034400.28219057
114Renin-angiotensin system_Homo sapiens_hsa046140.26269717
115Morphine addiction_Homo sapiens_hsa050320.25882859
116Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.25104030
117Nucleotide excision repair_Homo sapiens_hsa034200.24370514
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.23901732
119Melanoma_Homo sapiens_hsa052180.23863473
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.23769873
121Peroxisome_Homo sapiens_hsa041460.23497800
122Prolactin signaling pathway_Homo sapiens_hsa049170.22814018
123TGF-beta signaling pathway_Homo sapiens_hsa043500.21748800
124Prion diseases_Homo sapiens_hsa050200.21619632
125Glucagon signaling pathway_Homo sapiens_hsa049220.20625402
126PPAR signaling pathway_Homo sapiens_hsa033200.20483015
127ECM-receptor interaction_Homo sapiens_hsa045120.19375766
128Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19234306
129Long-term potentiation_Homo sapiens_hsa047200.19019597
130Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.16989229
131Cholinergic synapse_Homo sapiens_hsa047250.16927406
132Prostate cancer_Homo sapiens_hsa052150.16551033
133Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15930241
134Tyrosine metabolism_Homo sapiens_hsa003500.15604841
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.13943563
136Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.12641687
137Type II diabetes mellitus_Homo sapiens_hsa049300.10588808
138Arginine and proline metabolism_Homo sapiens_hsa003300.09452240
139Phenylalanine metabolism_Homo sapiens_hsa003600.09302276
140Autoimmune thyroid disease_Homo sapiens_hsa053200.08608851

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »