SEMA3C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)4.51797714
2sequestering of extracellular ligand from receptor (GO:0035581)4.34049184
3neuron projection extension involved in neuron projection guidance (GO:1902284)4.12914864
4axon extension involved in axon guidance (GO:0048846)4.12914864
5cell adhesion mediated by integrin (GO:0033627)4.08031333
6collagen fibril organization (GO:0030199)4.05442983
7lymphangiogenesis (GO:0001946)4.00653898
8COPI coating of Golgi vesicle (GO:0048205)3.89218369
9Golgi transport vesicle coating (GO:0048200)3.89218369
10chondrocyte proliferation (GO:0035988)3.85765343
11negative regulation of axon extension involved in axon guidance (GO:0048843)3.71585712
12negative regulation of keratinocyte proliferation (GO:0010839)3.58457177
13lymph vessel development (GO:0001945)3.56682324
14regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.56468145
15regulation of axon extension involved in axon guidance (GO:0048841)3.54296232
16extracellular fibril organization (GO:0043206)3.52058646
17mesodermal cell differentiation (GO:0048333)3.51266969
18protein heterotrimerization (GO:0070208)3.41432217
19surfactant homeostasis (GO:0043129)3.40198631
20type B pancreatic cell proliferation (GO:0044342)3.39143342
21artery development (GO:0060840)3.38270701
22chondrocyte development (GO:0002063)3.34906700
23negative regulation of cartilage development (GO:0061037)3.27448166
24retina vasculature morphogenesis in camera-type eye (GO:0061299)3.22498359
25lung lobe morphogenesis (GO:0060463)3.20768754
26vascular endothelial growth factor signaling pathway (GO:0038084)3.20673675
27regulation of axon guidance (GO:1902667)3.17769054
28cellular response to vitamin D (GO:0071305)3.14811418
29negative regulation of axon guidance (GO:1902668)3.11991076
30hippo signaling (GO:0035329)3.11171232
31renal filtration (GO:0097205)3.11144727
32cell-substrate adherens junction assembly (GO:0007045)3.09623736
33focal adhesion assembly (GO:0048041)3.09623736
34regulation of transforming growth factor beta2 production (GO:0032909)3.09360843
35endodermal cell differentiation (GO:0035987)3.07988351
36fibril organization (GO:0097435)3.06738111
37positive regulation of endothelial cell apoptotic process (GO:2000353)3.06705144
38positive regulation of keratinocyte differentiation (GO:0045618)3.01258511
39protein retention in ER lumen (GO:0006621)3.01019805
40negative regulation of fatty acid transport (GO:2000192)3.00669679
41adherens junction assembly (GO:0034333)3.00014480
42metanephric mesenchyme development (GO:0072075)2.99133817
43plasma membrane repair (GO:0001778)2.98829194
44endocardial cushion development (GO:0003197)2.97160792
45bundle of His cell to Purkinje myocyte communication (GO:0086069)2.95273151
46maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.94862918
47regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.92732758
48collagen metabolic process (GO:0032963)2.92667567
49epithelial cell-cell adhesion (GO:0090136)2.92572672
50kidney mesenchyme development (GO:0072074)2.90902232
51wound healing, spreading of epidermal cells (GO:0035313)2.90431470
52protein localization to endosome (GO:0036010)2.89777078
53collagen catabolic process (GO:0030574)2.87955143
54positive regulation of blood vessel endothelial cell migration (GO:0043536)2.86365556
55peptidyl-proline hydroxylation (GO:0019511)2.86170318
56multicellular organismal macromolecule metabolic process (GO:0044259)2.83979885
57chemical homeostasis within a tissue (GO:0048875)2.83388817
58cell migration involved in sprouting angiogenesis (GO:0002042)2.83141073
59barbed-end actin filament capping (GO:0051016)2.82298504
60branching involved in mammary gland duct morphogenesis (GO:0060444)2.81606857
61substrate-dependent cell migration (GO:0006929)2.79877987
62negative regulation of chondrocyte differentiation (GO:0032331)2.75212304
63mammary gland development (GO:0030879)2.74260904
64keratan sulfate catabolic process (GO:0042340)2.72759397
65extracellular matrix disassembly (GO:0022617)2.72494726
66multicellular organismal catabolic process (GO:0044243)2.72169320
67blood vessel maturation (GO:0001955)2.71824410
68regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.71811998
69positive regulation of epidermal cell differentiation (GO:0045606)2.71730496
70regulation of water loss via skin (GO:0033561)2.71691667
71branching involved in salivary gland morphogenesis (GO:0060445)2.70272848
72protein localization to cell surface (GO:0034394)2.69718799
73regulation of glucose import in response to insulin stimulus (GO:2001273)2.69468728
74multicellular organismal metabolic process (GO:0044236)2.69195447
75skin morphogenesis (GO:0043589)2.68344629
76protein hydroxylation (GO:0018126)2.68342883
77extracellular matrix organization (GO:0030198)2.68182437
78keratinocyte proliferation (GO:0043616)2.67240521
79extracellular structure organization (GO:0043062)2.67195585
80insulin-like growth factor receptor signaling pathway (GO:0048009)2.66424051
81basement membrane organization (GO:0071711)2.64889034
82cell junction assembly (GO:0034329)2.64597399
83lung vasculature development (GO:0060426)2.64146830
84glomerular basement membrane development (GO:0032836)2.63513984
85cell-substrate junction assembly (GO:0007044)2.62683372
86regulation of hippo signaling (GO:0035330)2.61592885
87membrane raft organization (GO:0031579)2.59016601
88regulation of keratinocyte proliferation (GO:0010837)2.58954747
89axon extension (GO:0048675)2.58146876
90planar cell polarity pathway involved in neural tube closure (GO:0090179)2.56676747
91endothelial cell morphogenesis (GO:0001886)2.56521371
92positive regulation of cartilage development (GO:0061036)2.56319672
93positive regulation of endothelial cell differentiation (GO:0045603)2.55478173
94regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.55182230
95wound healing, spreading of cells (GO:0044319)2.55164760
96peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.54942591
97stress fiber assembly (GO:0043149)2.54030689
98muscle cell migration (GO:0014812)2.53908032
99regulation of endothelial cell differentiation (GO:0045601)2.52901022
100* blood vessel remodeling (GO:0001974)2.52530867
101wound healing (GO:0042060)2.52403613
102establishment of planar polarity (GO:0001736)2.51873070
103establishment of tissue polarity (GO:0007164)2.51873070
104respiratory tube development (GO:0030323)2.51055674
105embryonic foregut morphogenesis (GO:0048617)2.50105245
106negative regulation of cell fate specification (GO:0009996)2.50046110
107extracellular negative regulation of signal transduction (GO:1900116)2.48859940
108extracellular regulation of signal transduction (GO:1900115)2.48859940
109germ cell migration (GO:0008354)2.48352899
110embryonic cranial skeleton morphogenesis (GO:0048701)2.48111512
111myoblast fusion (GO:0007520)2.47850516
112regulation of mesenchymal cell proliferation (GO:0010464)2.46137082
113COPII vesicle coating (GO:0048208)2.46043202
114heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.45398070
115epoxygenase P450 pathway (GO:0019373)2.45286613
116desmosome organization (GO:0002934)2.45259397
117* dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.45199035
118regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.44598704
119membrane protein ectodomain proteolysis (GO:0006509)2.44446547
120vocalization behavior (GO:0071625)2.44423500
121regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.44215286
122polarized epithelial cell differentiation (GO:0030859)2.42841468
123positive regulation of mesenchymal cell proliferation (GO:0002053)2.42797335
124midgut development (GO:0007494)2.42173875
125regulation of cardioblast differentiation (GO:0051890)2.40910872
126negative chemotaxis (GO:0050919)2.39559788
127bone trabecula formation (GO:0060346)2.39417420
128extracellular matrix assembly (GO:0085029)2.38807422
129cytoskeletal anchoring at plasma membrane (GO:0007016)2.37860223
130semaphorin-plexin signaling pathway (GO:0071526)2.37561954
131mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.36783258
132positive regulation of axon extension (GO:0045773)2.36555751
133positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.34731571
134renal system development (GO:0072001)2.34540569
135neural crest cell development (GO:0014032)2.34486008
136glomerular filtration (GO:0003094)2.34057080
137regulation of chondrocyte differentiation (GO:0032330)2.33851826
138cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.31516082
139cellular response to vitamin (GO:0071295)2.30907961
140negative regulation of catenin import into nucleus (GO:0035414)2.30419517
141regulation of glomerular filtration (GO:0003093)2.29367200
142positive regulation of vesicle fusion (GO:0031340)2.27423866
143regulation of cartilage development (GO:0061035)2.27063091
144mesenchymal-epithelial cell signaling (GO:0060638)2.27035609
145smooth muscle tissue development (GO:0048745)2.26650770
146membrane assembly (GO:0071709)2.26092060
147regulation of epithelial cell differentiation involved in kidney development (GO:2000696)2.25904062
148metanephric nephron tubule development (GO:0072234)2.25530356
149metanephric tubule development (GO:0072170)2.25530356

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.61938152
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.51383033
3RARG_19884340_ChIP-ChIP_MEFs_Mouse2.47299535
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.34647919
5EZH2_22144423_ChIP-Seq_EOC_Human2.33255531
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.20214792
7ZNF263_19887448_ChIP-Seq_K562_Human2.17201451
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.16408172
9CDX2_19796622_ChIP-Seq_MESCs_Mouse2.14206450
10* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.11586882
11* ZNF217_24962896_ChIP-Seq_MCF-7_Human2.11164990
12SMAD_19615063_ChIP-ChIP_OVARY_Human2.10125543
13* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.08046798
14EP300_21415370_ChIP-Seq_HL-1_Mouse2.05835845
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.03048525
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.98040777
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.96880765
18* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.95959836
19RNF2_18974828_ChIP-Seq_MESCs_Mouse1.95407665
20EZH2_18974828_ChIP-Seq_MESCs_Mouse1.95407665
21* CJUN_26792858_Chip-Seq_BT549_Human1.94596868
22CLOCK_20551151_ChIP-Seq_293T_Human1.93836268
23WT1_19549856_ChIP-ChIP_CCG9911_Human1.86953988
24* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.81323212
25CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.80521599
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.79026002
27NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.77700282
28NRF2_20460467_ChIP-Seq_MEFs_Mouse1.77700282
29GBX2_23144817_ChIP-Seq_PC3_Human1.77527808
30* TP53_18474530_ChIP-ChIP_U2OS_Human1.76140445
31KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.74971341
32JARID2_20064375_ChIP-Seq_MESCs_Mouse1.74667948
33JARID2_20075857_ChIP-Seq_MESCs_Mouse1.71460301
34ESR1_21235772_ChIP-Seq_MCF-7_Human1.69379545
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.68646582
36SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.67993269
37AR_21572438_ChIP-Seq_LNCaP_Human1.63320117
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.62008741
39* AHR_22903824_ChIP-Seq_MCF-7_Human1.60015574
40* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.58882156
41* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.58821854
42PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.55944770
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53314802
44EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.49993504
45* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.49853218
46* ARNT_22903824_ChIP-Seq_MCF-7_Human1.46786406
47TP53_16413492_ChIP-PET_HCT116_Human1.46468152
48* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.44652540
49RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44063775
50WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43919246
51RNF2_27304074_Chip-Seq_ESCs_Mouse1.43621733
52ESR2_21235772_ChIP-Seq_MCF-7_Human1.43380413
53* SOX2_20726797_ChIP-Seq_SW620_Human1.40849537
54UBF1/2_26484160_Chip-Seq_HMECs_Human1.39473104
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38164272
56TCF4_18268006_ChIP-ChIP_LS174T_Human1.38080366
57* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.37247353
58* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.35360013
59* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.35360013
60* ESR1_20079471_ChIP-ChIP_T-47D_Human1.34602010
61CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.32854561
62* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.32555367
63RUNX1_27514584_Chip-Seq_MCF-7_Human1.31970848
64ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.30494365
65* BCAT_22108803_ChIP-Seq_LS180_Human1.29260330
66RACK7_27058665_Chip-Seq_MCF-7_Human1.29223809
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29155879
68TBX20_22328084_ChIP-Seq_HEART_Mouse1.27792500
69TBX20_22080862_ChIP-Seq_HEART_Mouse1.27792500
70KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.26993334
71GATA3_24758297_ChIP-Seq_MCF-7_Human1.26759147
72GATA2_21666600_ChIP-Seq_HMVEC_Human1.26155745
73TP53_20018659_ChIP-ChIP_R1E_Mouse1.24921085
74* BRD4_25478319_ChIP-Seq_HGPS_Human1.22087803
75EZH2_27294783_Chip-Seq_ESCs_Mouse1.21773281
76FOXO3_23340844_ChIP-Seq_DLD1_Human1.21472149
77* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21000819
78* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.20806796
79BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.20487512
80* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18663470
81* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18504681
82ISL1_27105846_Chip-Seq_CPCs_Mouse1.18476664
83TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.14781685
84SUZ12_27294783_Chip-Seq_ESCs_Mouse1.14734051
85NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.14350902
86AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13450368
87CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13382325
88ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.11661985
89ZNF274_21170338_ChIP-Seq_K562_Hela1.10945312
90RXR_22108803_ChIP-Seq_LS180_Human1.09095770
91* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.08860584
92CDX2_20551321_ChIP-Seq_CACO-2_Human1.08307637
93* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07908628
94FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.06761553
95RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.06236082
96WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05418341
97SMAD4_21799915_ChIP-Seq_A2780_Human1.05173854
98NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04470751
99TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03986316
100* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03863846
101RING1B_27294783_Chip-Seq_NPCs_Mouse1.03336143
102* CBX2_27304074_Chip-Seq_ESCs_Mouse1.03288838
103* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02713373
104* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02501201
105* ATF3_27146783_Chip-Seq_COLON_Human1.02500242
106NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.01665832
107* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.01181307
108STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.01176237
109KLF5_25053715_ChIP-Seq_YYC3_Human1.00984124
110JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00891358
111SMAD3_21741376_ChIP-Seq_HESCs_Human1.00380959
112EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.00212153
113SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99980570
114TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.99669166
115TP63_23658742_ChIP-Seq_EP156T_Human0.98955433
116ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97039397
117HIF1A_21447827_ChIP-Seq_MCF-7_Human0.96900197
118JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96869015
119SALL1_21062744_ChIP-ChIP_HESCs_Human0.96511646
120* AR_25329375_ChIP-Seq_VCAP_Human0.96125167
121FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.95862745
122SALL4_18804426_ChIP-ChIP_XEN_Mouse0.95679965
123AR_21909140_ChIP-Seq_LNCAP_Human0.94979775
124MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94808796
125* BMI1_23680149_ChIP-Seq_NPCS_Mouse0.94653823
126ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.94280209
127ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93741649
128ELK3_25401928_ChIP-Seq_HUVEC_Human0.92644386
129BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.91367595
130* TP53_23651856_ChIP-Seq_MEFs_Mouse0.88680787
131TP53_22127205_ChIP-Seq_IMR90_Human0.88353056
132SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.88076663
133SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.87842745
134YAP1_20516196_ChIP-Seq_MESCs_Mouse0.87661586
135ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.86957409
136TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85340113
137* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.84985037
138DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.84172078
139UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.83467866
140ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.83452431
141Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.82133044
142ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.80726883
143* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.80657262

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.85557146
2MP0005275_abnormal_skin_tensile4.70666035
3MP0001958_emphysema3.57717891
4MP0004272_abnormal_basement_membrane3.49318671
5MP0005503_abnormal_tendon_morphology3.05828161
6MP0000537_abnormal_urethra_morphology3.01676505
7MP0000579_abnormal_nail_morphology2.98921523
8MP0003705_abnormal_hypodermis_morpholog2.91813111
9MP0010368_abnormal_lymphatic_system2.80029946
10MP0005623_abnormal_meninges_morphology2.67618477
11MP0001879_abnormal_lymphatic_vessel2.52028757
12MP0010234_abnormal_vibrissa_follicle2.50583090
13MP0003279_aneurysm2.11599019
14MP0006054_spinal_hemorrhage1.97073964
15* MP0009384_cardiac_valve_regurgitation1.93781312
16MP0002060_abnormal_skin_morphology1.93638486
17MP0002295_abnormal_pulmonary_circulatio1.92018275
18MP0003385_abnormal_body_wall1.88818253
19MP0003566_abnormal_cell_adhesion1.81229830
20MP0009780_abnormal_chondrocyte_physiolo1.80388165
21MP0003941_abnormal_skin_development1.76998417
22MP0000013_abnormal_adipose_tissue1.75967772
23MP0000534_abnormal_ureter_morphology1.64447378
24MP0010352_gastrointestinal_tract_polyps1.58692846
25MP0005257_abnormal_intraocular_pressure1.58423560
26MP0009250_abnormal_appendicular_skeleto1.57126193
27MP0005409_darkened_coat_color1.56187129
28MP0000516_abnormal_urinary_system1.55816446
29MP0005367_renal/urinary_system_phenotyp1.55816446
30MP0001299_abnormal_eye_distance/1.53309631
31MP0003091_abnormal_cell_migration1.52848958
32MP0009379_abnormal_foot_pigmentation1.51955362
33MP0003191_abnormal_cellular_cholesterol1.51913645
34MP0001177_atelectasis1.48277947
35MP0009053_abnormal_anal_canal1.41052522
36MP0002896_abnormal_bone_mineralization1.38579713
37MP0005508_abnormal_skeleton_morphology1.37962156
38MP0003045_fibrosis1.32018278
39MP0003942_abnormal_urinary_system1.31257799
40MP0002108_abnormal_muscle_morphology1.30744026
41MP0003115_abnormal_respiratory_system1.30446472
42MP0004484_altered_response_of1.27884962
43MP0002098_abnormal_vibrissa_morphology1.27078971
44MP0005167_abnormal_blood-brain_barrier1.25606367
45MP0000767_abnormal_smooth_muscle1.25399650
46MP0005388_respiratory_system_phenotype1.25398683
47MP0002133_abnormal_respiratory_system1.25398683
48MP0000627_abnormal_mammary_gland1.25140186
49MP0003453_abnormal_keratinocyte_physiol1.25126181
50MP0002282_abnormal_trachea_morphology1.24544298
51MP0000751_myopathy1.20959834
52MP0006138_congestive_heart_failure1.20322378
53MP0000762_abnormal_tongue_morphology1.19810049
54MP0001216_abnormal_epidermal_layer1.19647182
55MP0005171_absent_coat_pigmentation1.16948080
56MP0004858_abnormal_nervous_system1.16398040
57MP0000427_abnormal_hair_cycle1.15301831
58MP0000749_muscle_degeneration1.13810815
59MP0004264_abnormal_extraembryonic_tissu1.08991028
60MP0008004_abnormal_stomach_pH1.08620821
61MP0005595_abnormal_vascular_smooth1.08052419
62MP0002796_impaired_skin_barrier1.07205752
63MP0000467_abnormal_esophagus_morphology1.06886814
64MP0004084_abnormal_cardiac_muscle1.06581420
65MP0010678_abnormal_skin_adnexa1.05777857
66MP0005023_abnormal_wound_healing1.05580105
67MP0010030_abnormal_orbit_morphology1.05163750
68MP0000377_abnormal_hair_follicle1.04851475
69MP0003755_abnormal_palate_morphology1.04801921
70MP0000733_abnormal_muscle_development1.04374278
71MP0002168_other_aberrant_phenotype1.02380902
72MP0001542_abnormal_bone_strength1.00471180
73MP0004782_abnormal_surfactant_physiolog0.99173166
74MP0002234_abnormal_pharynx_morphology0.98301480
75MP0000759_abnormal_skeletal_muscle0.97995711
76MP0010386_abnormal_urinary_bladder0.96171821
77MP0002837_dystrophic_cardiac_calcinosis0.92951683
78MP0000163_abnormal_cartilage_morphology0.91924754
79MP0002877_abnormal_melanocyte_morpholog0.91429255
80MP0003935_abnormal_craniofacial_develop0.90630036
81MP0005164_abnormal_response_to0.90444010
82MP0001849_ear_inflammation0.89991048
83MP0010771_integument_phenotype0.88696562
84MP0004134_abnormal_chest_morphology0.87620255
85MP0002115_abnormal_skeleton_extremities0.86659145
86MP0004233_abnormal_muscle_weight0.83836024
87MP0003937_abnormal_limbs/digits/tail_de0.83688817
88MP0003950_abnormal_plasma_membrane0.83226406
89MP0001348_abnormal_lacrimal_gland0.83201486
90MP0004883_abnormal_blood_vessel0.81344646
91MP0005197_abnormal_uvea_morphology0.80295694
92MP0004185_abnormal_adipocyte_glucose0.79752810
93MP0005620_abnormal_muscle_contractility0.79471732
94MP0000003_abnormal_adipose_tissue0.78201045
95MP0000566_synostosis0.78026811
96MP0003300_gastrointestinal_ulcer0.75727079
97MP0002972_abnormal_cardiac_muscle0.75483367
98MP0002233_abnormal_nose_morphology0.74451742
99MP0008260_abnormal_autophagy0.73751528
100MP0005501_abnormal_skin_physiology0.73523598
101MP0003828_pulmonary_edema0.73494965
102MP0000383_abnormal_hair_follicle0.73385555
103* MP0002925_abnormal_cardiovascular_devel0.73057582
104MP0000538_abnormal_urinary_bladder0.72899510
105MP0002128_abnormal_blood_circulation0.72844449
106MP0000428_abnormal_craniofacial_morphol0.72693418
107MP0003283_abnormal_digestive_organ0.71974026
108MP0002177_abnormal_outer_ear0.70541547
109MP0001270_distended_abdomen0.70369043
110MP0001881_abnormal_mammary_gland0.69735551
111MP0000462_abnormal_digestive_system0.68487884
112MP0002113_abnormal_skeleton_development0.68403790
113MP0009931_abnormal_skin_appearance0.68257076
114MP0005193_abnormal_anterior_eye0.67925214
115MP0002269_muscular_atrophy0.67645778
116MP0004036_abnormal_muscle_relaxation0.66976146
117MP0004087_abnormal_muscle_fiber0.66278398
118MP0001243_abnormal_dermal_layer0.65791269
119MP0005076_abnormal_cell_differentiation0.65158468
120MP0000432_abnormal_head_morphology0.65069373
121MP0000750_abnormal_muscle_regeneration0.65063234
122MP0005248_abnormal_Harderian_gland0.64992683

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.48835484
2Protrusio acetabuli (HP:0003179)5.19873953
3Atrophic scars (HP:0001075)5.06230568
4Aortic dissection (HP:0002647)4.37225391
5Shallow orbits (HP:0000586)4.22255429
6Aortic aneurysm (HP:0004942)3.96664952
7Broad metatarsal (HP:0001783)3.71599588
8Fragile skin (HP:0001030)3.66742732
9Ankle contracture (HP:0006466)3.46596323
10Vascular tortuosity (HP:0004948)3.39040323
11Soft skin (HP:0000977)3.30490120
12Absent frontal sinuses (HP:0002688)3.29269186
13Cerebral aneurysm (HP:0004944)3.28421284
14Arterial tortuosity (HP:0005116)3.19622435
15Type 1 muscle fiber predominance (HP:0003803)3.16359479
16Dilatation of the ascending aorta (HP:0005111)3.13783634
17Abnormality of nail color (HP:0100643)3.10273630
18Spinal rigidity (HP:0003306)2.98901181
19Increased connective tissue (HP:0009025)2.87138891
20Mitral valve prolapse (HP:0001634)2.86473425
21Bladder diverticulum (HP:0000015)2.85647502
22Wrist flexion contracture (HP:0001239)2.84918671
23Abnormality of dentin (HP:0010299)2.76097607
24Peritonitis (HP:0002586)2.73525810
25Pterygium (HP:0001059)2.73360305
26Neonatal short-limb short stature (HP:0008921)2.70481997
27Wormian bones (HP:0002645)2.67831413
28Follicular hyperkeratosis (HP:0007502)2.64878858
29Mitral stenosis (HP:0001718)2.61460789
30Overgrowth (HP:0001548)2.59565911
31Microglossia (HP:0000171)2.55981387
32Buphthalmos (HP:0000557)2.55515679
33Cervical subluxation (HP:0003308)2.54076700
34Natal tooth (HP:0000695)2.50210064
35Spondylolisthesis (HP:0003302)2.49252917
36Increased variability in muscle fiber diameter (HP:0003557)2.47466915
37Vertebral compression fractures (HP:0002953)2.46261331
38Onycholysis (HP:0001806)2.39629445
39Mildly elevated creatine phosphokinase (HP:0008180)2.38471305
40Right ventricular cardiomyopathy (HP:0011663)2.37812992
41Popliteal pterygium (HP:0009756)2.36033116
42Hyperextensible skin (HP:0000974)2.35705145
43Milia (HP:0001056)2.34555183
44Plantar hyperkeratosis (HP:0007556)2.32931094
45Hematochezia (HP:0002573)2.30334426
46Round ear (HP:0100830)2.29111613
47Hyperacusis (HP:0010780)2.25075579
48Osteolytic defects of the phalanges of the hand (HP:0009771)2.23838992
49Osteolytic defects of the hand bones (HP:0009699)2.23838992
50Bronchomalacia (HP:0002780)2.23181482
51Cardiovascular calcification (HP:0011915)2.21879822
52Genu recurvatum (HP:0002816)2.18266819
53Venous abnormality (HP:0002624)2.16416356
54Thick nail (HP:0001805)2.16247324
55Abnormality of skeletal muscle fiber size (HP:0012084)2.14971256
56Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.14908587
57Distal lower limb muscle weakness (HP:0009053)2.14813212
58Abnormality of the frontal sinuses (HP:0002687)2.13985014
59Bell-shaped thorax (HP:0001591)2.11644898
60Blue sclerae (HP:0000592)2.08791359
61Venous insufficiency (HP:0005293)2.08686960
62Subacute progressive viral hepatitis (HP:0006572)2.07179007
63Nail dystrophy (HP:0008404)2.06833594
64Camptodactyly of toe (HP:0001836)2.06143296
65Aplasia involving bones of the extremities (HP:0009825)2.05074776
66Aplasia involving bones of the upper limbs (HP:0009823)2.05074776
67Aplasia of the phalanges of the hand (HP:0009802)2.05074776
68Abnormality of the acetabulum (HP:0003170)2.04324714
69Broad ribs (HP:0000885)2.03986036
70Ulnar bowing (HP:0003031)2.03918261
71Short hallux (HP:0010109)2.02301390
72Hydroureter (HP:0000072)2.00642029
73Fragile nails (HP:0001808)1.99488264
74Advanced eruption of teeth (HP:0006288)1.99041620
75Coronal craniosynostosis (HP:0004440)1.98916197
76Flat cornea (HP:0007720)1.98655152
77Breech presentation (HP:0001623)1.97673106
78Aneurysm (HP:0002617)1.97622292
79Wide anterior fontanel (HP:0000260)1.96476279
80Hypoplasia of the iris (HP:0007676)1.93713418
81Morphological abnormality of the middle ear (HP:0008609)1.93136757
82Mitral regurgitation (HP:0001653)1.90961888
83Asymmetry of the thorax (HP:0001555)1.90680152
84Ridged nail (HP:0001807)1.90329256
85Thin bony cortex (HP:0002753)1.90089226
86Spinal cord compression (HP:0002176)1.89195372
87Hyporeflexia of lower limbs (HP:0002600)1.87709237
88Bowel diverticulosis (HP:0005222)1.86524570
89Elbow flexion contracture (HP:0002987)1.86332021
90Striae distensae (HP:0001065)1.84260503
91Deviation of the hallux (HP:0010051)1.83737714
92Hypoplasia of dental enamel (HP:0006297)1.81898040
93Scapular winging (HP:0003691)1.81801165
94Joint laxity (HP:0001388)1.80981489
95Alopecia of scalp (HP:0002293)1.80963584
96Broad face (HP:0000283)1.80652199
97Aplasia/Hypoplasia of the hallux (HP:0008362)1.80597653
98Osteoarthritis (HP:0002758)1.80169881
99Aortic valve stenosis (HP:0001650)1.79952749
100Germ cell neoplasia (HP:0100728)1.77964948
101Aortic regurgitation (HP:0001659)1.77900865
102Hallux valgus (HP:0001822)1.77477022
103Mesomelia (HP:0003027)1.77434352
104Joint stiffness (HP:0001387)1.76876092
105Back pain (HP:0003418)1.76750911
106Abnormality of the distal phalanges of the toes (HP:0010182)1.75968587
107Knee flexion contracture (HP:0006380)1.75819537
108Ovoid vertebral bodies (HP:0003300)1.75700035
109Hip contracture (HP:0003273)1.75181424
110Ectopia lentis (HP:0001083)1.75018358
111Congenital glaucoma (HP:0001087)1.73692862
112Coxa vara (HP:0002812)1.72798241
113Selective tooth agenesis (HP:0001592)1.72037033
114Flat acetabular roof (HP:0003180)1.70262230
115Femoral bowing (HP:0002980)1.69205809
116Acanthosis nigricans (HP:0000956)1.69129709
117Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.68664796
118Hypoventilation (HP:0002791)1.67423185
119Rectal prolapse (HP:0002035)1.67082872
120Insidious onset (HP:0003587)1.65851180
121Termporal pattern (HP:0011008)1.65851180
122Long toe (HP:0010511)1.65563412
123Infantile muscular hypotonia (HP:0008947)1.65223311
124Stridor (HP:0010307)1.65097972
125Deep philtrum (HP:0002002)1.64588257
126Potter facies (HP:0002009)1.62685027
127Facial shape deformation (HP:0011334)1.62685027
128Short nail (HP:0001799)1.60086147
129Hyperactive renin-angiotensin system (HP:0000841)1.59955547
130Tibial bowing (HP:0002982)1.59767964
131Abnormal delivery (HP:0001787)1.58266096
132Syringomyelia (HP:0003396)1.58051692
133Spinal cord lesions (HP:0100561)1.58051692
134Muscle fiber splitting (HP:0003555)1.57956880
135Biconcave vertebral bodies (HP:0004586)1.57927615
136Abnormality of the fetal cardiovascular system (HP:0010948)1.56982515
137Single umbilical artery (HP:0001195)1.56982515

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR23.37823897
2TTN3.12348864
3FRK3.01086390
4EPHB22.82785881
5PDGFRA2.80641999
6FER2.73509974
7FGFR22.67078884
8TIE12.64424551
9LATS12.40819867
10MYLK2.22299135
11MST1R2.21933906
12EPHA22.20159937
13MUSK2.19667766
14TRIB32.14254704
15PIK3CA2.05211600
16TGFBR21.95091155
17EPHA31.75419966
18MAPKAPK31.74178654
19LIMK11.66404370
20MAP3K21.66388975
21RIPK11.64130365
22LATS21.61256520
23PAK31.60062059
24NTRK11.60004122
25PTK21.59166562
26DMPK1.47148270
27MET1.46508848
28PTK61.43460733
29ERBB31.42857258
30PTK2B1.41991760
31MAP2K11.39751130
32MST41.38644055
33EEF2K1.36804878
34PAK21.32883439
35TRPM71.27218711
36RPS6KB21.25699375
37TESK11.23983070
38PAK41.22801697
39IRAK31.22006642
40NEK61.20954334
41LRRK21.15251580
42CAMK1G1.13986247
43ERBB41.12492541
44PDGFRB1.08931621
45PBK1.06306488
46ROCK11.05177081
47LMTK21.03552005
48ICK1.03163452
49CAMK1D1.00006896
50PRKCE0.99665734
51RPS6KA20.99510945
52PLK20.98652312
53ARAF0.97436607
54MAP3K30.95912446
55MARK10.95227055
56FGFR10.93505601
57MAP3K60.92379633
58CAMKK20.89971807
59NME20.86847969
60ROCK20.86774353
61FGFR40.83759684
62STK380.83453770
63PIM20.83090460
64RET0.79068539
65ILK0.77689298
66EIF2AK10.77064162
67SMG10.75744394
68TYRO30.75364733
69ABL20.74170925
70CAMK2G0.73993267
71STK30.73631332
72STK38L0.72370550
73SIK10.72277979
74PDK20.70691729
75NUAK10.70127400
76CAMK2B0.66166739
77CDC42BPA0.65369238
78GSK3A0.65102671
79BCR0.64309365
80PHKG10.63937627
81PHKG20.63937627
82NTRK30.62653338
83FGFR30.59210830
84SRC0.59133351
85PRKCH0.58918575
86INSR0.56713268
87TGFBR10.55136726
88MAP3K120.55097198
89SCYL20.54939425
90PRKD10.54715343
91PRKD20.53821346
92ERN10.53690128
93RPS6KB10.53345975
94KSR20.53068112
95OBSCN0.52477397
96MAP2K20.52457091
97PRKG20.51800352
98MAP3K40.51646015
99AKT30.49407087
100MINK10.48752118
101CASK0.48735164
102JAK10.48306251
103CAMK2D0.47835410
104PRKD30.46651062
105FLT30.45534438
106CHUK0.44961698
107BMX0.44845317
108ADRBK10.43883710
109EPHB10.43815216
110PDK30.43202176
111PDK40.43202176
112IGF1R0.42128397
113MTOR0.41711823
114PAK60.41613129
115PIK3CG0.41443684
116WNK10.39580552
117MAP2K40.39223787
118CDK80.38915251
119NEK90.37551822
120MOS0.37027360
121KSR10.36664484
122MELK0.36663218
123DAPK30.36042390
124EPHA40.35699179
125PKN20.35446122
126STK240.35431909
127GRK10.34967793
128GRK50.34926620
129EGFR0.34683409
130CAMKK10.33893590
131CLK10.33831517
132EIF2AK30.33088490
133FGR0.32405591
134MAPKAPK20.32039764
135PNCK0.31419652
136CDK60.29985318
137MAP3K90.28922826
138ABL10.28023429
139PRKCI0.27453578
140SGK30.27038146
141EIF2AK20.26244456
142AKT20.23287291
143RPS6KC10.21782681

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.41505377
2Focal adhesion_Homo sapiens_hsa045102.57936099
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.18079773
4Adherens junction_Homo sapiens_hsa045202.17892330
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.92717842
6Dilated cardiomyopathy_Homo sapiens_hsa054141.90181113
7Proteoglycans in cancer_Homo sapiens_hsa052051.86630874
8AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.78216687
9Protein digestion and absorption_Homo sapiens_hsa049741.74606845
10Amoebiasis_Homo sapiens_hsa051461.73513969
11Hippo signaling pathway_Homo sapiens_hsa043901.72793427
12* Axon guidance_Homo sapiens_hsa043601.71972900
13Tight junction_Homo sapiens_hsa045301.64104692
14Small cell lung cancer_Homo sapiens_hsa052221.57919004
15Thyroid cancer_Homo sapiens_hsa052161.55881251
16Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.52256846
17Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.51605836
18TGF-beta signaling pathway_Homo sapiens_hsa043501.51574996
19Basal cell carcinoma_Homo sapiens_hsa052171.48118785
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.47634438
21Bladder cancer_Homo sapiens_hsa052191.42891133
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.40366602
23Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.36279141
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.35159051
25Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.31718013
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.28958657
27Melanoma_Homo sapiens_hsa052181.27514468
28Rap1 signaling pathway_Homo sapiens_hsa040151.26094110
29Hedgehog signaling pathway_Homo sapiens_hsa043401.24503252
30Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.23987969
31Melanogenesis_Homo sapiens_hsa049161.23673200
32PI3K-Akt signaling pathway_Homo sapiens_hsa041511.22024570
33Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.18005169
34Thyroid hormone signaling pathway_Homo sapiens_hsa049191.17670441
35Regulation of actin cytoskeleton_Homo sapiens_hsa048101.16171215
36Glioma_Homo sapiens_hsa052141.15380241
37Mineral absorption_Homo sapiens_hsa049781.13505534
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.12586831
39mTOR signaling pathway_Homo sapiens_hsa041501.11161883
40Wnt signaling pathway_Homo sapiens_hsa043101.08996039
41MicroRNAs in cancer_Homo sapiens_hsa052061.08613868
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.08162681
43Vascular smooth muscle contraction_Homo sapiens_hsa042701.07538455
44Gap junction_Homo sapiens_hsa045401.03412341
45AMPK signaling pathway_Homo sapiens_hsa041521.03022837
46Renin secretion_Homo sapiens_hsa049241.01569153
47Vibrio cholerae infection_Homo sapiens_hsa051101.00461853
48Gastric acid secretion_Homo sapiens_hsa049711.00241971
49Pathways in cancer_Homo sapiens_hsa052000.99362113
50Sphingolipid metabolism_Homo sapiens_hsa006000.99200005
51Ovarian steroidogenesis_Homo sapiens_hsa049130.96959095
52Insulin signaling pathway_Homo sapiens_hsa049100.96805332
53Oxytocin signaling pathway_Homo sapiens_hsa049210.96264873
54Renal cell carcinoma_Homo sapiens_hsa052110.95536917
55Longevity regulating pathway - mammal_Homo sapiens_hsa042110.94474222
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94351775
57Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93990338
58Endometrial cancer_Homo sapiens_hsa052130.92820912
59Platelet activation_Homo sapiens_hsa046110.92793774
60Salivary secretion_Homo sapiens_hsa049700.92608852
61Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.92313007
62GnRH signaling pathway_Homo sapiens_hsa049120.90761969
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.89552822
64Estrogen signaling pathway_Homo sapiens_hsa049150.89453677
65Non-small cell lung cancer_Homo sapiens_hsa052230.88883163
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88516168
67Pancreatic cancer_Homo sapiens_hsa052120.87921144
68Prostate cancer_Homo sapiens_hsa052150.87715122
69Prolactin signaling pathway_Homo sapiens_hsa049170.86387054
70Viral myocarditis_Homo sapiens_hsa054160.85352530
71Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.85125370
72Ras signaling pathway_Homo sapiens_hsa040140.84886847
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84827174
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81949918
75Chronic myeloid leukemia_Homo sapiens_hsa052200.81327692
76p53 signaling pathway_Homo sapiens_hsa041150.80105415
77Colorectal cancer_Homo sapiens_hsa052100.79901640
78Steroid biosynthesis_Homo sapiens_hsa001000.79242298
79Cholinergic synapse_Homo sapiens_hsa047250.79005924
80Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.78705875
81Phagosome_Homo sapiens_hsa041450.78664171
82Toxoplasmosis_Homo sapiens_hsa051450.77187279
83N-Glycan biosynthesis_Homo sapiens_hsa005100.76947408
84Long-term depression_Homo sapiens_hsa047300.76718897
85Lysosome_Homo sapiens_hsa041420.76316343
86Acute myeloid leukemia_Homo sapiens_hsa052210.75326925
87Prion diseases_Homo sapiens_hsa050200.75199043
88Insulin resistance_Homo sapiens_hsa049310.74690254
89GABAergic synapse_Homo sapiens_hsa047270.74426512
90Other glycan degradation_Homo sapiens_hsa005110.73866820
91ErbB signaling pathway_Homo sapiens_hsa040120.73798806
92Malaria_Homo sapiens_hsa051440.71765596
93Salmonella infection_Homo sapiens_hsa051320.70071208
94Serotonergic synapse_Homo sapiens_hsa047260.69937965
95Thyroid hormone synthesis_Homo sapiens_hsa049180.69859049
96Inositol phosphate metabolism_Homo sapiens_hsa005620.69787571
97Dorso-ventral axis formation_Homo sapiens_hsa043200.69732642
98Circadian entrainment_Homo sapiens_hsa047130.67823054
99Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67409626
100VEGF signaling pathway_Homo sapiens_hsa043700.66396920
101Hepatitis C_Homo sapiens_hsa051600.65399024
102Notch signaling pathway_Homo sapiens_hsa043300.64323104
103Taste transduction_Homo sapiens_hsa047420.63913654
104Synaptic vesicle cycle_Homo sapiens_hsa047210.63759000
105Endocytosis_Homo sapiens_hsa041440.63381908
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.61653147
107Dopaminergic synapse_Homo sapiens_hsa047280.60847719
108cAMP signaling pathway_Homo sapiens_hsa040240.59939958
109Aldosterone synthesis and secretion_Homo sapiens_hsa049250.59727785
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.58749327
111Choline metabolism in cancer_Homo sapiens_hsa052310.58268838
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.57828726
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57247366
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.56710770
115HIF-1 signaling pathway_Homo sapiens_hsa040660.56441259
116Renin-angiotensin system_Homo sapiens_hsa046140.56135749
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55934829
118Galactose metabolism_Homo sapiens_hsa000520.55551748
119Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55134522
120Shigellosis_Homo sapiens_hsa051310.54769748
121TNF signaling pathway_Homo sapiens_hsa046680.54588420
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54233001
123Rheumatoid arthritis_Homo sapiens_hsa053230.54053443
124MAPK signaling pathway_Homo sapiens_hsa040100.52539652
125Calcium signaling pathway_Homo sapiens_hsa040200.50077535
126Pentose phosphate pathway_Homo sapiens_hsa000300.50077181
127Pancreatic secretion_Homo sapiens_hsa049720.49961161
128FoxO signaling pathway_Homo sapiens_hsa040680.49957352
129Long-term potentiation_Homo sapiens_hsa047200.48456923
130Insulin secretion_Homo sapiens_hsa049110.48173624
131Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46690422
132Sulfur metabolism_Homo sapiens_hsa009200.46683965
133Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.40903927
134Glucagon signaling pathway_Homo sapiens_hsa049220.40263792

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