SEPHS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by RNA (GO:0060966)6.39792998
2regulation of posttranscriptional gene silencing (GO:0060147)6.39792998
3regulation of gene silencing by miRNA (GO:0060964)6.39792998
4establishment of integrated proviral latency (GO:0075713)6.01237244
5pre-miRNA processing (GO:0031054)5.37153509
6DNA unwinding involved in DNA replication (GO:0006268)5.34260906
7protein complex localization (GO:0031503)5.06038333
8L-serine metabolic process (GO:0006563)5.00583265
9protein localization to kinetochore (GO:0034501)4.61069728
10establishment of viral latency (GO:0019043)4.46983284
11DNA strand elongation involved in DNA replication (GO:0006271)4.41957496
12positive regulation of SMAD protein import into nucleus (GO:0060391)4.22432538
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.17752943
14DNA strand elongation (GO:0022616)4.17730802
15nuclear pore organization (GO:0006999)4.11794798
16mitotic metaphase plate congression (GO:0007080)4.11567449
17DNA replication initiation (GO:0006270)4.08551344
18kinetochore organization (GO:0051383)4.01677410
19DNA replication-dependent nucleosome assembly (GO:0006335)4.00174502
20DNA replication-dependent nucleosome organization (GO:0034723)4.00174502
21protein localization to chromosome, centromeric region (GO:0071459)4.00094037
22nuclear pore complex assembly (GO:0051292)3.99755708
23regulation of histone H3-K9 methylation (GO:0051570)3.99181968
24mitotic nuclear envelope disassembly (GO:0007077)3.95047547
25telomere maintenance via semi-conservative replication (GO:0032201)3.94847644
26cellular protein complex localization (GO:0034629)3.93804328
27sister chromatid segregation (GO:0000819)3.90853076
28mitotic sister chromatid segregation (GO:0000070)3.80470437
29regulation of cell fate specification (GO:0042659)3.77976268
30folic acid-containing compound biosynthetic process (GO:0009396)3.74235658
31histone arginine methylation (GO:0034969)3.70711936
32IMP biosynthetic process (GO:0006188)3.70035425
33nucleobase biosynthetic process (GO:0046112)3.69978143
34ribosomal small subunit assembly (GO:0000028)3.68586570
35regulation of spindle organization (GO:0090224)3.66966356
36nuclear envelope disassembly (GO:0051081)3.64935405
37membrane disassembly (GO:0030397)3.64935405
38mitotic recombination (GO:0006312)3.63748219
39regulation of helicase activity (GO:0051095)3.62948009
40metaphase plate congression (GO:0051310)3.62026628
41negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.59533458
42CENP-A containing nucleosome assembly (GO:0034080)3.58669534
43chromatin remodeling at centromere (GO:0031055)3.58524588
44formation of translation preinitiation complex (GO:0001731)3.58143127
45mitotic chromosome condensation (GO:0007076)3.54343811
46kinetochore assembly (GO:0051382)3.52370225
47telomere maintenance via recombination (GO:0000722)3.51531995
48regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.47877696
49DNA replication checkpoint (GO:0000076)3.46635024
50regulation of gene silencing (GO:0060968)3.45579248
51DNA duplex unwinding (GO:0032508)3.45348140
52DNA geometric change (GO:0032392)3.43276721
53purine nucleobase biosynthetic process (GO:0009113)3.42688188
54maturation of SSU-rRNA (GO:0030490)3.41531604
55negative regulation of histone methylation (GO:0031061)3.40586519
56DNA replication-independent nucleosome organization (GO:0034724)3.40086523
57DNA replication-independent nucleosome assembly (GO:0006336)3.40086523
58negative regulation of gene silencing (GO:0060969)3.37225501
59regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.35373507
60regulation of translational fidelity (GO:0006450)3.33024995
61DNA topological change (GO:0006265)3.33002480
62establishment of chromosome localization (GO:0051303)3.32415338
63negative regulation of RNA splicing (GO:0033119)3.31634037
64mitotic sister chromatid cohesion (GO:0007064)3.27121508
65serine family amino acid biosynthetic process (GO:0009070)3.26628806
66nucleotide-excision repair, DNA gap filling (GO:0006297)3.26508399
67viral transcription (GO:0019083)3.25613505
68L-alpha-amino acid transmembrane transport (GO:1902475)3.23103905
69translational termination (GO:0006415)3.23102995
70telomere maintenance via telomere lengthening (GO:0010833)3.22060605
71paraxial mesoderm development (GO:0048339)3.19665651
72regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.19255740
73spindle checkpoint (GO:0031577)3.18902579
74negative regulation of chromosome segregation (GO:0051985)3.18679186
75regulation of sister chromatid cohesion (GO:0007063)3.18432967
76spindle assembly checkpoint (GO:0071173)3.17880628
77IMP metabolic process (GO:0046040)3.17643598
78cell fate commitment involved in formation of primary germ layer (GO:0060795)3.17239276
79regulation of mitotic spindle organization (GO:0060236)3.17157199
80negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15342392
81negative regulation of sister chromatid segregation (GO:0033046)3.15342392
82negative regulation of mitotic sister chromatid separation (GO:2000816)3.15342392
83negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15342392
84attachment of spindle microtubules to kinetochore (GO:0008608)3.15328836
85regulation of chromosome segregation (GO:0051983)3.14799012
86mitotic spindle assembly checkpoint (GO:0007094)3.14283945
87regulation of mitotic metaphase/anaphase transition (GO:0030071)3.12337222
88dosage compensation (GO:0007549)3.10960003
89negative regulation of mRNA processing (GO:0050686)3.10703565
90pore complex assembly (GO:0046931)3.09732606
91ATP-dependent chromatin remodeling (GO:0043044)3.08984517
92protein-DNA complex disassembly (GO:0032986)3.08572869
93nucleosome disassembly (GO:0006337)3.08572869
94DNA ligation (GO:0006266)3.07495406
95chromatin assembly (GO:0031497)3.07209199
96mitotic spindle checkpoint (GO:0071174)3.07142537
97chromatin assembly or disassembly (GO:0006333)3.06784509
98positive regulation of chromosome segregation (GO:0051984)3.05208961
99regulation of chromatin silencing (GO:0031935)3.04960628
100negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03873230
101regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.03542986
102histone exchange (GO:0043486)3.02816353
103translational initiation (GO:0006413)3.02146458
104spliceosomal snRNP assembly (GO:0000387)3.00901000
105double-strand break repair via nonhomologous end joining (GO:0006303)2.99140320
106non-recombinational repair (GO:0000726)2.99140320
107protein localization to chromosome (GO:0034502)2.98555140
108negative regulation of mRNA metabolic process (GO:1903312)2.97036252
109translational elongation (GO:0006414)2.96503126
110mRNA splicing, via spliceosome (GO:0000398)2.96386619
111RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.96386619
112RNA splicing, via transesterification reactions (GO:0000375)2.96001314
113regulation of SMAD protein import into nucleus (GO:0060390)2.95435376
114ribosomal large subunit biogenesis (GO:0042273)2.94767029
115peptidyl-arginine omega-N-methylation (GO:0035247)2.94496712
116nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92086434
117notochord development (GO:0030903)2.91341239
118convergent extension (GO:0060026)2.90605936
119regulation of mitotic sister chromatid separation (GO:0010965)2.89280734
120regulation of mitotic sister chromatid segregation (GO:0033047)2.89280734
121regulation of sister chromatid segregation (GO:0033045)2.89280734
122lung-associated mesenchyme development (GO:0060484)2.88782340
123nuclear envelope organization (GO:0006998)2.87839796
124DNA conformation change (GO:0071103)2.87594056
125regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.86722819
126regulation of mitotic spindle checkpoint (GO:1903504)2.86722819
127somatic diversification of immune receptors via somatic mutation (GO:0002566)2.84841411
128somatic hypermutation of immunoglobulin genes (GO:0016446)2.84841411
129ribosome assembly (GO:0042255)2.84677503
130ribosome biogenesis (GO:0042254)2.84094997
131termination of RNA polymerase II transcription (GO:0006369)2.83419853
132DNA damage response, detection of DNA damage (GO:0042769)2.83390286
133chromosome segregation (GO:0007059)2.82832574
134translesion synthesis (GO:0019985)2.80485846
135ribonucleoprotein complex biogenesis (GO:0022613)2.78178951
136heterochromatin organization (GO:0070828)2.78171624
137spliceosomal complex assembly (GO:0000245)2.77265167
138regulation of centrosome cycle (GO:0046605)2.76298618

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.67107281
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.35673499
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.14834716
4MYC_18555785_ChIP-Seq_MESCs_Mouse4.12691521
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.64574416
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.49471310
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.94149710
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.82369202
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.74269074
10KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.62441162
11KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.62441162
12KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.62441162
13AR_21909140_ChIP-Seq_LNCAP_Human2.62319777
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.49834144
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.46740927
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.38378098
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.36214019
18XRN2_22483619_ChIP-Seq_HELA_Human2.34354641
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.25169177
20E2F1_21310950_ChIP-Seq_MCF-7_Human2.18288205
21ETS1_20019798_ChIP-Seq_JURKAT_Human2.12693590
22KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.10645434
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.07531784
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03531951
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.99816341
26MYC_22102868_ChIP-Seq_BL_Human1.95544616
27TP63_19390658_ChIP-ChIP_HaCaT_Human1.95295576
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.94057752
29* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.93319769
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.92596463
31SOX2_16153702_ChIP-ChIP_HESCs_Human1.89095257
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85202689
33* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.83699503
34JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.81093832
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.75571329
36TTF2_22483619_ChIP-Seq_HELA_Human1.73842075
37POU5F1_16153702_ChIP-ChIP_HESCs_Human1.71223065
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71111164
39VDR_23849224_ChIP-Seq_CD4+_Human1.70917889
40DCP1A_22483619_ChIP-Seq_HELA_Human1.67964412
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67876001
42CIITA_25753668_ChIP-Seq_RAJI_Human1.66239079
43FOXP3_21729870_ChIP-Seq_TREG_Human1.63675437
44* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.63575916
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.60810362
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.58808754
47SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.58307584
48ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57977498
49GABP_19822575_ChIP-Seq_HepG2_Human1.55487774
50TCF3_18692474_ChIP-Seq_MESCs_Mouse1.55486988
51YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51474034
52ELK1_19687146_ChIP-ChIP_HELA_Human1.42540434
53KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.41856475
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.41568915
55SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.40983645
56KDM5A_27292631_Chip-Seq_BREAST_Human1.39924763
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39100579
58THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37702034
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.36415367
60E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.36376164
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36276467
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36200189
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.35648297
64ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35025106
65SALL1_21062744_ChIP-ChIP_HESCs_Human1.30317761
66* HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28770078
67* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.27708551
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25493764
69SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.25408699
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25392238
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.25000365
72KLF4_18555785_ChIP-Seq_MESCs_Mouse1.24841329
73NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.24015744
74NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.23187171
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21214876
76FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20090476
77* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16630514
78ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15775824
79HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.15238996
80GATA1_26923725_Chip-Seq_HPCs_Mouse1.14931363
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.14157478
82VDR_21846776_ChIP-Seq_THP-1_Human1.14076456
83FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.13837304
84TCF3_18692474_ChIP-Seq_MEFs_Mouse1.13006377
85* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.12977827
86NANOG_21062744_ChIP-ChIP_HESCs_Human1.12915861
87STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12735979
88NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.12728985
89PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10181380
90SOX2_18692474_ChIP-Seq_MESCs_Mouse1.07103350
91NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.06799467
92SOX17_20123909_ChIP-Seq_XEN_Mouse1.06396879
93SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.05239706
94CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.04592766
95MYC_18940864_ChIP-ChIP_HL60_Human1.03596978
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02786325
97KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02556953
98ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01831354
99MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.99983313
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.99758752
101YY1_21170310_ChIP-Seq_MESCs_Mouse0.99333829
102SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98440916
103TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98165262
104NANOG_18692474_ChIP-Seq_MEFs_Mouse0.96090346
105RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96010828
106* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.95997347
107* CHD1_26751641_Chip-Seq_LNCaP_Human0.95926036
108TFEB_21752829_ChIP-Seq_HELA_Human0.94021604
109* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.93694589
110POU5F1_16518401_ChIP-PET_MESCs_Mouse0.91779187
111* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90709602
112SOX2_18692474_ChIP-Seq_MEFs_Mouse0.88962218
113OCT4_18692474_ChIP-Seq_MEFs_Mouse0.87316381
114NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.84270602
115CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.83678212
116DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83622582
117HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.82691033
118CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82648332
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.82294302
120BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81393299
121TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.80786722
122PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78419075
123ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.78401953

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002254_reproductive_system_inflammat4.25902486
2MP0003693_abnormal_embryo_hatching3.78298360
3MP0010094_abnormal_chromosome_stability3.74415370
4MP0003111_abnormal_nucleus_morphology3.58822724
5MP0004957_abnormal_blastocyst_morpholog3.46441659
6MP0003077_abnormal_cell_cycle3.23443607
7MP0010030_abnormal_orbit_morphology2.93991786
8MP0009053_abnormal_anal_canal2.76959633
9MP0008057_abnormal_DNA_replication2.65063469
10MP0008007_abnormal_cellular_replicative2.64588777
11MP0003123_paternal_imprinting2.60929278
12MP0000537_abnormal_urethra_morphology2.29175492
13MP0008932_abnormal_embryonic_tissue2.27672291
14MP0008058_abnormal_DNA_repair2.24919822
15MP0010352_gastrointestinal_tract_polyps2.17448579
16MP0001730_embryonic_growth_arrest2.13791024
17MP0000350_abnormal_cell_proliferation2.04225999
18MP0006292_abnormal_olfactory_placode1.91318830
19MP0003705_abnormal_hypodermis_morpholog1.89243087
20MP0001672_abnormal_embryogenesis/_devel1.84266784
21MP0005380_embryogenesis_phenotype1.84266784
22MP0005076_abnormal_cell_differentiation1.83769504
23MP0001697_abnormal_embryo_size1.78752048
24MP0002085_abnormal_embryonic_tissue1.73554440
25MP0001293_anophthalmia1.73527876
26MP0004197_abnormal_fetal_growth/weight/1.73246607
27MP0003136_yellow_coat_color1.71035966
28MP0010307_abnormal_tumor_latency1.68357551
29MP0003567_abnormal_fetal_cardiomyocyte1.67770799
30MP0003984_embryonic_growth_retardation1.67353325
31MP0002088_abnormal_embryonic_growth/wei1.66880335
32MP0002396_abnormal_hematopoietic_system1.65309410
33MP0002084_abnormal_developmental_patter1.63598859
34MP0003121_genomic_imprinting1.51584105
35MP0002080_prenatal_lethality1.50796217
36MP0001188_hyperpigmentation1.50270462
37MP0003937_abnormal_limbs/digits/tail_de1.48172103
38MP0000566_synostosis1.47315127
39MP0002086_abnormal_extraembryonic_tissu1.44969632
40MP0003890_abnormal_embryonic-extraembry1.44546980
41MP0003119_abnormal_digestive_system1.43132956
42MP0003942_abnormal_urinary_system1.42598463
43MP0009672_abnormal_birth_weight1.39686117
44MP0003315_abnormal_perineum_morphology1.38525202
45MP0003806_abnormal_nucleotide_metabolis1.38463177
46MP0000049_abnormal_middle_ear1.37466416
47MP0002796_impaired_skin_barrier1.33989195
48MP0006054_spinal_hemorrhage1.31681748
49MP0000579_abnormal_nail_morphology1.31188591
50MP0004808_abnormal_hematopoietic_stem1.31015971
51MP0002111_abnormal_tail_morphology1.28128230
52MP0000490_abnormal_crypts_of1.27403703
53MP0004185_abnormal_adipocyte_glucose1.25446355
54MP0003385_abnormal_body_wall1.23968583
55MP0000428_abnormal_craniofacial_morphol1.23823894
56MP0003115_abnormal_respiratory_system1.23737871
57MP0001299_abnormal_eye_distance/1.23539318
58MP0002938_white_spotting1.23263955
59MP0002092_abnormal_eye_morphology1.23192402
60MP0008789_abnormal_olfactory_epithelium1.21814089
61MP0000313_abnormal_cell_death1.19037354
62MP0009703_decreased_birth_body1.14471483
63MP0003786_premature_aging1.11724445
64MP0002932_abnormal_joint_morphology1.09375050
65MP0001915_intracranial_hemorrhage1.09190910
66MP0001286_abnormal_eye_development1.07926899
67MP0003935_abnormal_craniofacial_develop1.07730882
68MP0004233_abnormal_muscle_weight1.06461203
69MP0002019_abnormal_tumor_incidence1.05051665
70MP0003755_abnormal_palate_morphology1.04786682
71MP0009250_abnormal_appendicular_skeleto1.04541812
72MP0002697_abnormal_eye_size1.04309189
73MP0002249_abnormal_larynx_morphology1.00229685
74MP0000432_abnormal_head_morphology0.98885330
75MP0002653_abnormal_ependyma_morphology0.97876479
76MP0002282_abnormal_trachea_morphology0.97161035
77MP0009697_abnormal_copulation0.95178338
78MP0001849_ear_inflammation0.95031124
79MP0005501_abnormal_skin_physiology0.93185221
80MP0009379_abnormal_foot_pigmentation0.92025046
81MP0000733_abnormal_muscle_development0.90510140
82MP0002233_abnormal_nose_morphology0.89725804
83MP0004272_abnormal_basement_membrane0.88520436
84MP0000534_abnormal_ureter_morphology0.87711073
85MP0000516_abnormal_urinary_system0.86712814
86MP0005367_renal/urinary_system_phenotyp0.86712814
87MP0005248_abnormal_Harderian_gland0.86482862
88MP0006035_abnormal_mitochondrial_morpho0.85177997
89MP0008877_abnormal_DNA_methylation0.84723975
90MP0002116_abnormal_craniofacial_bone0.83218000
91MP0003718_maternal_effect0.82909752
92MP0003566_abnormal_cell_adhesion0.82005501
93MP0000762_abnormal_tongue_morphology0.81229746
94MP0005187_abnormal_penis_morphology0.80364314
95MP0000703_abnormal_thymus_morphology0.79241678
96MP0001346_abnormal_lacrimal_gland0.78813042
97MP0003861_abnormal_nervous_system0.77836091
98MP0002160_abnormal_reproductive_system0.76453284
99MP0002114_abnormal_axial_skeleton0.76426374
100MP0004264_abnormal_extraembryonic_tissu0.76163527
101MP0005023_abnormal_wound_healing0.75549111
102MP0002081_perinatal_lethality0.75353670
103MP0001177_atelectasis0.74925821
104MP0002089_abnormal_postnatal_growth/wei0.74774633
105MP0003122_maternal_imprinting0.74143974
106MP0003938_abnormal_ear_development0.73798493
107MP0003941_abnormal_skin_development0.72631718
108MP0010234_abnormal_vibrissa_follicle0.72105624
109MP0009333_abnormal_splenocyte_physiolog0.72038965
110MP0002109_abnormal_limb_morphology0.71398566
111MP0005508_abnormal_skeleton_morphology0.70405114
112MP0001661_extended_life_span0.70240046
113MP0003787_abnormal_imprinting0.70194247
114MP0002925_abnormal_cardiovascular_devel0.69500887
115MP0002210_abnormal_sex_determination0.69236232
116MP0000477_abnormal_intestine_morphology0.67632834
117MP0001119_abnormal_female_reproductive0.66904641
118MP0004133_heterotaxia0.65723025
119MP0001145_abnormal_male_reproductive0.64775103
120MP0002751_abnormal_autonomic_nervous0.64559401
121MP0001545_abnormal_hematopoietic_system0.64100777
122MP0005397_hematopoietic_system_phenotyp0.64100777
123MP0008438_abnormal_cutaneous_collagen0.64097799
124MP0005503_abnormal_tendon_morphology0.63334192
125MP0003878_abnormal_ear_physiology0.62163921
126MP0005377_hearing/vestibular/ear_phenot0.62163921
127MP0009278_abnormal_bone_marrow0.61822634
128MP0008770_decreased_survivor_rate0.60770121
129MP0001340_abnormal_eyelid_morphology0.59882220
130MP0000358_abnormal_cell_content/0.59247857
131MP0010630_abnormal_cardiac_muscle0.59152019
132MP0001529_abnormal_vocalization0.57579235

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)3.96960703
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.96960703
3Colon cancer (HP:0003003)3.71866156
4Spastic diplegia (HP:0001264)3.55934274
5Cortical dysplasia (HP:0002539)3.39566834
6Hepatoblastoma (HP:0002884)3.39119522
7Selective tooth agenesis (HP:0001592)3.32995869
8Septo-optic dysplasia (HP:0100842)3.28262743
9Degeneration of anterior horn cells (HP:0002398)3.26745557
10Abnormality of the anterior horn cell (HP:0006802)3.26745557
11Reticulocytopenia (HP:0001896)3.15354312
12Abnormality of the 4th metacarpal (HP:0010012)3.09894441
13Multiple enchondromatosis (HP:0005701)3.07003513
14Medulloblastoma (HP:0002885)3.06264616
15Ependymoma (HP:0002888)3.01254613
16Choanal stenosis (HP:0000452)2.99355095
17Increased nuchal translucency (HP:0010880)2.97685358
18Birth length less than 3rd percentile (HP:0003561)2.93981843
19Aplasia/Hypoplasia of the patella (HP:0006498)2.85289251
20Patellar aplasia (HP:0006443)2.80588333
21Bilateral microphthalmos (HP:0007633)2.77816297
22Abnormal number of incisors (HP:0011064)2.76818115
23Breast hypoplasia (HP:0003187)2.75851444
24Rhabdomyosarcoma (HP:0002859)2.71040971
25Atresia of the external auditory canal (HP:0000413)2.69789190
26Deviation of the thumb (HP:0009603)2.56439700
27Proximal placement of thumb (HP:0009623)2.55183818
28Renal duplication (HP:0000075)2.53128445
29Volvulus (HP:0002580)2.44266280
30Facial cleft (HP:0002006)2.41940497
31Abnormal lung lobation (HP:0002101)2.39382192
32Maternal diabetes (HP:0009800)2.34855771
33Impulsivity (HP:0100710)2.32758810
34Abnormality of the septum pellucidum (HP:0007375)2.31788736
35Spinal cord lesions (HP:0100561)2.30777181
36Syringomyelia (HP:0003396)2.30777181
37Chronic bronchitis (HP:0004469)2.27904753
38Oral leukoplakia (HP:0002745)2.26301357
39Esophageal atresia (HP:0002032)2.22634525
40Neoplasm of striated muscle (HP:0009728)2.20095791
41Partial duplication of thumb phalanx (HP:0009944)2.19802500
42Ectopic kidney (HP:0000086)2.19172805
43Duplication of thumb phalanx (HP:0009942)2.19012895
44Neoplasm of the pancreas (HP:0002894)2.18348938
45Absent septum pellucidum (HP:0001331)2.15683195
46Stenosis of the external auditory canal (HP:0000402)2.15539969
47Abnormality of the astrocytes (HP:0100707)2.15379083
48Astrocytoma (HP:0009592)2.15379083
49Hypoglycemic seizures (HP:0002173)2.14579683
50Abnormality of chromosome stability (HP:0003220)2.13521918
51Meckel diverticulum (HP:0002245)2.13434105
52Hyperglycinemia (HP:0002154)2.11752033
53Short middle phalanx of the 5th finger (HP:0004220)2.10620529
54Glioma (HP:0009733)2.07389319
55Abnormality of the salivary glands (HP:0010286)2.07302927
56Skull defect (HP:0001362)2.07248494
57Basal cell carcinoma (HP:0002671)2.06339855
58Horseshoe kidney (HP:0000085)2.06294309
59Neoplasm of the adrenal cortex (HP:0100641)2.06256784
60Progressive external ophthalmoplegia (HP:0000590)2.05714174
61Absent radius (HP:0003974)2.05572135
62Homocystinuria (HP:0002156)2.05018324
63Abnormality of homocysteine metabolism (HP:0010919)2.05018324
64Uterine neoplasm (HP:0010784)2.04798880
65Abnormality of cells of the erythroid lineage (HP:0012130)2.04770711
66Protrusio acetabuli (HP:0003179)2.04733142
67Abnormality of the ileum (HP:0001549)2.02740100
68Embryonal neoplasm (HP:0002898)2.02045955
69Short 5th finger (HP:0009237)2.01907913
70Myelomeningocele (HP:0002475)1.99273101
71Shoulder girdle muscle weakness (HP:0003547)1.98728558
72Turricephaly (HP:0000262)1.96406429
73High anterior hairline (HP:0009890)1.96401208
74Progressive muscle weakness (HP:0003323)1.95607872
75Abnormality of the lacrimal duct (HP:0011481)1.95515062
76Pseudobulbar signs (HP:0002200)1.94740565
77Hyperglycinuria (HP:0003108)1.94631076
78Intestinal polyp (HP:0005266)1.94265700
79Rectal fistula (HP:0100590)1.94189704
80Rectovaginal fistula (HP:0000143)1.94189704
81Abnormality of the calcaneus (HP:0008364)1.93838941
82Aplasia/Hypoplasia of the sternum (HP:0006714)1.93679921
83Chromsome breakage (HP:0040012)1.93662074
84Overriding aorta (HP:0002623)1.92795588
85Intestinal polyposis (HP:0200008)1.92789565
86Cutis marmorata (HP:0000965)1.92763876
8711 pairs of ribs (HP:0000878)1.92299986
88Abnormal number of erythroid precursors (HP:0012131)1.92028281
89Generalized hypotonia (HP:0001290)1.91073964
90Aplasia involving forearm bones (HP:0009822)1.89612630
91Absent forearm bone (HP:0003953)1.89612630
92Absent eyebrow (HP:0002223)1.89244050
93Missing ribs (HP:0000921)1.89082376
94Skin tags (HP:0010609)1.88652334
95Vaginal fistula (HP:0004320)1.87978189
96Preauricular skin tag (HP:0000384)1.87771708
97Breast aplasia (HP:0100783)1.87049400
98Partial duplication of the phalanx of hand (HP:0009999)1.86797162
99Aplasia/Hypoplasia of the breasts (HP:0010311)1.84563694
100Shallow orbits (HP:0000586)1.84000356
101Abnormality of the labia minora (HP:0012880)1.83671391
102Malignant gastrointestinal tract tumors (HP:0006749)1.83640502
103Gastrointestinal carcinoma (HP:0002672)1.83640502
104Cutaneous syndactyly (HP:0012725)1.83438099
105Facial hemangioma (HP:0000329)1.83204704
106Long eyelashes (HP:0000527)1.82230536
107Abnormality of glycine metabolism (HP:0010895)1.82181245
108Abnormality of serine family amino acid metabolism (HP:0010894)1.82181245
109Neoplasm of the colon (HP:0100273)1.82125668
110Large earlobe (HP:0009748)1.81375086
111Agnosia (HP:0010524)1.81144928
112Carpal bone hypoplasia (HP:0001498)1.81132207
113Small intestinal stenosis (HP:0012848)1.79935212
114Duodenal stenosis (HP:0100867)1.79935212
115Rectal prolapse (HP:0002035)1.79916743
116Cellular immunodeficiency (HP:0005374)1.79762771
117Broad thumb (HP:0011304)1.79597083
118Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.78744921
119Bifid tongue (HP:0010297)1.78346127
120Deep philtrum (HP:0002002)1.78258724
121Ovarian neoplasm (HP:0100615)1.78247256
122Dysphonia (HP:0001618)1.77218404
123Absent eyelashes (HP:0000561)1.76958077
124Biliary tract neoplasm (HP:0100574)1.76220396
125Trismus (HP:0000211)1.76215820
126Triphalangeal thumb (HP:0001199)1.75830478
127Rough bone trabeculation (HP:0100670)1.75506614
128Neuroblastic tumors (HP:0004376)1.75196922
129Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.75196922
130Neuroblastoma (HP:0003006)1.75196922
131Primitive neuroectodermal tumor (HP:0030065)1.75196922
132High pitched voice (HP:0001620)1.74835908
133Macrocytic anemia (HP:0001972)1.73637170
134Squamous cell carcinoma (HP:0002860)1.73595875
135Atrophy/Degeneration involving motor neurons (HP:0007373)1.72662372
136Aplasia/Hypoplasia of the uvula (HP:0010293)1.72215800
137Nephroblastoma (Wilms tumor) (HP:0002667)1.72176085
138Neoplasm of the oral cavity (HP:0100649)1.71705369
139Abnormality of serum amino acid levels (HP:0003112)1.71433432
140Abdominal situs inversus (HP:0003363)1.71103548
141Abnormality of abdominal situs (HP:0011620)1.71103548
142Pancreatic islet-cell hyperplasia (HP:0004510)1.70905900
143Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.70789963
144Abnormality of pyrimidine metabolism (HP:0004353)1.70397782
145Breast carcinoma (HP:0003002)1.69883781
146Broad phalanges of the hand (HP:0009768)1.68598275
147Trigonocephaly (HP:0000243)1.67346091
148Rib fusion (HP:0000902)1.67046247
149Absent thumb (HP:0009777)1.66749887
150Diastasis recti (HP:0001540)1.65915006
151Chromosomal breakage induced by crosslinking agents (HP:0003221)1.65797900
152Embryonal renal neoplasm (HP:0011794)1.65289943
153Deviation of the hallux (HP:0010051)1.64877874
154Hallux valgus (HP:0001822)1.64404493
155Angiofibromas (HP:0010615)1.63913570
156Adenoma sebaceum (HP:0009720)1.63913570
157Tracheoesophageal fistula (HP:0002575)1.63809395
158Cafe-au-lait spot (HP:0000957)1.63385376
159Abnormality of the duodenum (HP:0002246)1.62611068
160Abnormality of the preputium (HP:0100587)1.62585148

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.33066871
2BUB14.30534046
3WEE13.46758600
4VRK22.93471545
5NEK22.91629671
6MKNK12.78605063
7TAF12.77830700
8SRPK12.77256620
9MAP3K102.73365681
10SMG12.55840962
11TLK12.53887504
12PASK2.33744943
13TTK2.24421659
14EIF2AK12.21118659
15NEK12.19505394
16TNIK1.91740270
17PLK11.87933396
18MKNK21.83213337
19CDK191.72756663
20EEF2K1.68892413
21PKN21.66471616
22TSSK61.64544350
23CDK71.63753310
24TGFBR11.63599605
25PLK31.63412500
26ATR1.57681806
27AURKB1.57411297
28DYRK31.57383704
29TESK21.53435919
30BRSK21.53336174
31RPS6KA41.51293332
32ACVR1B1.51144602
33MAP3K91.51085701
34CDK41.47015351
35CDK121.45337298
36RPS6KB21.45143814
37MAP3K81.35588980
38PAK41.35444682
39CDK61.33138521
40CHEK21.32409582
41STK41.30757658
42PLK41.26346324
43STK101.22886869
44AURKA1.19656859
45VRK11.19605660
46CHEK11.15663613
47LATS11.11955768
48CAMK1D1.10098875
49FGFR21.09311019
50CAMK1G1.08975780
51STK241.03910473
52TRIB31.01272423
53BRSK11.00606362
54NEK90.99874214
55MELK0.98988352
56CDK80.97303224
57ERBB30.96726221
58NME20.95562123
59CCNB10.95303286
60PNCK0.95073587
61SCYL20.94472053
62ERBB40.93802735
63STK30.93503643
64CDK20.92941939
65ATM0.89806162
66PIM10.87923672
67FGFR10.87623440
68FLT30.86839764
69PBK0.86756383
70MST40.86217328
71NME10.84020137
72LRRK20.82443999
73BRD40.80665829
74ZAK0.79933478
75EPHB20.74418801
76CDK10.72242525
77DMPK0.71525225
78MTOR0.70634385
79ALK0.69193978
80CSNK1G10.67624581
81EIF2AK20.67339198
82FGFR40.66136853
83BMX0.65206086
84STK160.64428162
85EIF2AK30.63489356
86DYRK1B0.63270461
87LATS20.60970938
88NUAK10.60074521
89CSNK2A10.59339828
90CSNK2A20.58435495
91NTRK10.56142062
92CLK10.54820545
93PAK10.54184214
94TYRO30.53424645
95ILK0.52738286
96PTK60.52450466
97TESK10.51904551
98PAK20.49849854
99PRKCI0.49124373
100PIM20.46667519
101EPHA20.44981783
102NLK0.44775761
103CDK11A0.43534532
104CDK150.42465169
105KDR0.41243886
106CDK180.40933667
107PDGFRA0.40796560
108DDR20.40648341
109ERBB20.39950149
110CDK30.39195880
111MAPK110.38542370
112PTK20.38351708
113DAPK10.38021231
114RPS6KA10.37978119
115CSNK1E0.37770752
116TTN0.37674416
117PRKDC0.37393719
118YES10.37126701
119AKT20.36298162
120CDK140.35360310
121STK38L0.35001415
122WNK30.34829204
123CSNK1G20.33549132
124GSK3B0.33381289
125DYRK20.32623348
126CDK90.32345476
127MAPK140.32133530
128TRIM280.31655999
129CSNK1A1L0.30378800
130BRAF0.29726404
131RPS6KA50.29024976
132CHUK0.28606450
133BCKDK0.28494272
134AKT10.28003965
135MAPK90.27207990

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.73218784
2Mismatch repair_Homo sapiens_hsa034304.03013504
3Spliceosome_Homo sapiens_hsa030403.44128256
4Cell cycle_Homo sapiens_hsa041103.05420890
5Base excision repair_Homo sapiens_hsa034103.03116982
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.02420960
7One carbon pool by folate_Homo sapiens_hsa006703.01583655
8RNA transport_Homo sapiens_hsa030133.01263158
9Ribosome_Homo sapiens_hsa030102.79111784
10Nucleotide excision repair_Homo sapiens_hsa034202.61543227
11Homologous recombination_Homo sapiens_hsa034402.55948541
12Proteasome_Homo sapiens_hsa030502.21087146
13RNA polymerase_Homo sapiens_hsa030202.18062996
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.14164364
15mRNA surveillance pathway_Homo sapiens_hsa030152.07051821
16Pyrimidine metabolism_Homo sapiens_hsa002401.92832839
17Fanconi anemia pathway_Homo sapiens_hsa034601.92147743
18Non-homologous end-joining_Homo sapiens_hsa034501.84898545
19Vitamin B6 metabolism_Homo sapiens_hsa007501.70404994
20Systemic lupus erythematosus_Homo sapiens_hsa053221.68602888
21RNA degradation_Homo sapiens_hsa030181.66127103
22Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64942610
23p53 signaling pathway_Homo sapiens_hsa041151.55775568
24Basal transcription factors_Homo sapiens_hsa030221.38106302
25Pyruvate metabolism_Homo sapiens_hsa006201.32046802
26Basal cell carcinoma_Homo sapiens_hsa052171.31836631
27Viral carcinogenesis_Homo sapiens_hsa052031.19922892
28MicroRNAs in cancer_Homo sapiens_hsa052061.18142349
29Steroid biosynthesis_Homo sapiens_hsa001001.17281070
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.14780240
31Thyroid cancer_Homo sapiens_hsa052161.13882841
32Hippo signaling pathway_Homo sapiens_hsa043901.07197923
33Epstein-Barr virus infection_Homo sapiens_hsa051691.05255098
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03727056
35Oocyte meiosis_Homo sapiens_hsa041141.02637583
36Biosynthesis of amino acids_Homo sapiens_hsa012301.01098253
37Small cell lung cancer_Homo sapiens_hsa052220.99638766
38HTLV-I infection_Homo sapiens_hsa051660.98832050
39Cysteine and methionine metabolism_Homo sapiens_hsa002700.98806212
40Drug metabolism - other enzymes_Homo sapiens_hsa009830.94323838
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91690609
42Herpes simplex infection_Homo sapiens_hsa051680.91509546
43Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90304882
44Colorectal cancer_Homo sapiens_hsa052100.88812419
45TGF-beta signaling pathway_Homo sapiens_hsa043500.84944712
46* Selenocompound metabolism_Homo sapiens_hsa004500.84584880
47Chronic myeloid leukemia_Homo sapiens_hsa052200.83906261
48Hedgehog signaling pathway_Homo sapiens_hsa043400.82226695
49Bladder cancer_Homo sapiens_hsa052190.81558627
50Lysine degradation_Homo sapiens_hsa003100.81084346
51Purine metabolism_Homo sapiens_hsa002300.80359881
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79350706
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78435274
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78181672
55Notch signaling pathway_Homo sapiens_hsa043300.77310692
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.76834087
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72407305
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72179667
59Protein export_Homo sapiens_hsa030600.70075381
60Huntingtons disease_Homo sapiens_hsa050160.68852279
61Antigen processing and presentation_Homo sapiens_hsa046120.68231077
62Pentose phosphate pathway_Homo sapiens_hsa000300.68052261
63Adherens junction_Homo sapiens_hsa045200.67293415
64Sulfur relay system_Homo sapiens_hsa041220.66532548
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64747840
66Folate biosynthesis_Homo sapiens_hsa007900.64416528
67Arginine and proline metabolism_Homo sapiens_hsa003300.62769143
68Propanoate metabolism_Homo sapiens_hsa006400.61866601
69Fatty acid elongation_Homo sapiens_hsa000620.61138367
70Alcoholism_Homo sapiens_hsa050340.57790452
71Prostate cancer_Homo sapiens_hsa052150.56888589
72Viral myocarditis_Homo sapiens_hsa054160.56741823
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.56713864
74Carbon metabolism_Homo sapiens_hsa012000.56640998
75Endometrial cancer_Homo sapiens_hsa052130.54795414
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.53978623
77Vitamin digestion and absorption_Homo sapiens_hsa049770.52624707
78Non-small cell lung cancer_Homo sapiens_hsa052230.50676976
79Pathways in cancer_Homo sapiens_hsa052000.48895188
80Wnt signaling pathway_Homo sapiens_hsa043100.48748704
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48563561
82Arginine biosynthesis_Homo sapiens_hsa002200.48067770
83Hepatitis B_Homo sapiens_hsa051610.47509077
84Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.46060484
85Glutathione metabolism_Homo sapiens_hsa004800.45852623
86Proteoglycans in cancer_Homo sapiens_hsa052050.45372457
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44749425
88Apoptosis_Homo sapiens_hsa042100.44220560
89Parkinsons disease_Homo sapiens_hsa050120.44144454
90Legionellosis_Homo sapiens_hsa051340.42607210
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42014315
92Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40893257
93Pancreatic cancer_Homo sapiens_hsa052120.40857132
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39710032
95Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.38274580
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37624938
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.37480080
98Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.37015002
99* Metabolic pathways_Homo sapiens_hsa011000.34262134
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33509065
101Melanoma_Homo sapiens_hsa052180.32277028
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31605031
103Acute myeloid leukemia_Homo sapiens_hsa052210.30810412
104mTOR signaling pathway_Homo sapiens_hsa041500.29548931
105Tight junction_Homo sapiens_hsa045300.27931764
106Shigellosis_Homo sapiens_hsa051310.27821985
107Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.27247271
108N-Glycan biosynthesis_Homo sapiens_hsa005100.26035390
109PI3K-Akt signaling pathway_Homo sapiens_hsa041510.25031109
110Fatty acid metabolism_Homo sapiens_hsa012120.24890238
111Melanogenesis_Homo sapiens_hsa049160.24399051
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23471907
113FoxO signaling pathway_Homo sapiens_hsa040680.21967564
114Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.21644503
115Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.20006703
116Glucagon signaling pathway_Homo sapiens_hsa049220.19492283
117Oxidative phosphorylation_Homo sapiens_hsa001900.18757647
118Measles_Homo sapiens_hsa051620.18685657
119Regulation of actin cytoskeleton_Homo sapiens_hsa048100.18104110
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17861257
121Galactose metabolism_Homo sapiens_hsa000520.17714101
122Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.16837702
123AMPK signaling pathway_Homo sapiens_hsa041520.16778854
124HIF-1 signaling pathway_Homo sapiens_hsa040660.15410734
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.13963950
126Primary bile acid biosynthesis_Homo sapiens_hsa001200.13841590
127Focal adhesion_Homo sapiens_hsa045100.12100655
128Leukocyte transendothelial migration_Homo sapiens_hsa046700.10206103

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »