

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of sarcomere organization (GO:0060297) | 5.96783184 |
| 2 | DNA deamination (GO:0045006) | 5.89759584 |
| 3 | respiratory chain complex IV assembly (GO:0008535) | 4.40967813 |
| 4 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 4.38158503 |
| 5 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 4.11679094 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.09902655 |
| 7 | ribonucleoprotein complex disassembly (GO:0032988) | 4.06499792 |
| 8 | negative regulation of organelle assembly (GO:1902116) | 4.06346684 |
| 9 | embryonic viscerocranium morphogenesis (GO:0048703) | 3.93610917 |
| 10 | positive regulation of gastrulation (GO:2000543) | 3.90619490 |
| 11 | rRNA catabolic process (GO:0016075) | 3.83874615 |
| 12 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.83807790 |
| 13 | regulation of skeletal muscle contraction (GO:0014819) | 3.83607446 |
| 14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.82499495 |
| 15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.82499495 |
| 16 | NADH dehydrogenase complex assembly (GO:0010257) | 3.82499495 |
| 17 | pericardium development (GO:0060039) | 3.74953289 |
| 18 | axoneme assembly (GO:0035082) | 3.74155599 |
| 19 | organelle disassembly (GO:1903008) | 3.73971733 |
| 20 | behavioral response to nicotine (GO:0035095) | 3.73385199 |
| 21 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.70899883 |
| 22 | protein polyglutamylation (GO:0018095) | 3.70456490 |
| 23 | DNA demethylation (GO:0080111) | 3.68419277 |
| 24 | negative regulation of telomere maintenance (GO:0032205) | 3.68123271 |
| 25 | adaptation of signaling pathway (GO:0023058) | 3.67226020 |
| 26 | cytochrome complex assembly (GO:0017004) | 3.64434370 |
| 27 | secondary heart field specification (GO:0003139) | 3.56428399 |
| 28 | heart field specification (GO:0003128) | 3.56428399 |
| 29 | head development (GO:0060322) | 3.55997602 |
| 30 | negative regulation of muscle hypertrophy (GO:0014741) | 3.53722972 |
| 31 | response to redox state (GO:0051775) | 3.48799901 |
| 32 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.44371664 |
| 33 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.39809954 |
| 34 | plasma membrane repair (GO:0001778) | 3.39729790 |
| 35 | protein complex biogenesis (GO:0070271) | 3.38523682 |
| 36 | protein neddylation (GO:0045116) | 3.36265658 |
| 37 | oxidative demethylation (GO:0070989) | 3.34186449 |
| 38 | cytidine metabolic process (GO:0046087) | 3.29783650 |
| 39 | cytidine catabolic process (GO:0006216) | 3.29783650 |
| 40 | cytidine deamination (GO:0009972) | 3.29783650 |
| 41 | regulation of action potential (GO:0098900) | 3.26725216 |
| 42 | positive regulation of microtubule polymerization (GO:0031116) | 3.23298000 |
| 43 | platelet dense granule organization (GO:0060155) | 3.20350036 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.19923516 |
| 45 | DNA dealkylation (GO:0035510) | 3.17098038 |
| 46 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.14574631 |
| 47 | kidney morphogenesis (GO:0060993) | 3.07727362 |
| 48 | negative regulation of heart growth (GO:0061117) | 3.07134403 |
| 49 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 3.07134403 |
| 50 | regulation of alkaline phosphatase activity (GO:0010692) | 3.06832380 |
| 51 | striated muscle atrophy (GO:0014891) | 3.04963366 |
| 52 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.04450429 |
| 53 | cornea development in camera-type eye (GO:0061303) | 3.03815749 |
| 54 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 3.03338844 |
| 55 | response to pheromone (GO:0019236) | 3.03311443 |
| 56 | rRNA modification (GO:0000154) | 3.02002850 |
| 57 | nodal signaling pathway (GO:0038092) | 3.01669343 |
| 58 | regulation of cilium movement (GO:0003352) | 2.97033944 |
| 59 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.96857153 |
| 60 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.95000825 |
| 61 | protein localization to cilium (GO:0061512) | 2.94531943 |
| 62 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 2.90964425 |
| 63 | protein targeting to vacuole (GO:0006623) | 2.88893837 |
| 64 | protein targeting to lysosome (GO:0006622) | 2.88893837 |
| 65 | establishment of protein localization to vacuole (GO:0072666) | 2.88893837 |
| 66 | intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) | 2.88762603 |
| 67 | multicellular organism reproduction (GO:0032504) | 2.87561745 |
| 68 | somite rostral/caudal axis specification (GO:0032525) | 2.86713187 |
| 69 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.85258469 |
| 70 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.85223202 |
| 71 | positive regulation of immune response to tumor cell (GO:0002839) | 2.82385344 |
| 72 | regulation of immune response to tumor cell (GO:0002837) | 2.82385344 |
| 73 | regulation of response to tumor cell (GO:0002834) | 2.82385344 |
| 74 | positive regulation of response to tumor cell (GO:0002836) | 2.82385344 |
| 75 | glomerulus development (GO:0032835) | 2.81755296 |
| 76 | protein K6-linked ubiquitination (GO:0085020) | 2.81282521 |
| 77 | glycerophospholipid catabolic process (GO:0046475) | 2.79331099 |
| 78 | cellular ketone body metabolic process (GO:0046950) | 2.78467918 |
| 79 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.78137624 |
| 80 | membrane raft organization (GO:0031579) | 2.78117180 |
| 81 | regulation of membrane repolarization (GO:0060306) | 2.77805756 |
| 82 | adult feeding behavior (GO:0008343) | 2.75307064 |
| 83 | negative regulation of protein localization to cell surface (GO:2000009) | 2.71414251 |
| 84 | replication fork processing (GO:0031297) | 2.70561005 |
| 85 | maturation of 5.8S rRNA (GO:0000460) | 2.69447262 |
| 86 | nephron epithelium morphogenesis (GO:0072088) | 2.69241919 |
| 87 | nephron tubule morphogenesis (GO:0072078) | 2.69241919 |
| 88 | rRNA methylation (GO:0031167) | 2.69102944 |
| 89 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.67143488 |
| 90 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.66938382 |
| 91 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.65773824 |
| 92 | short-term memory (GO:0007614) | 2.65314540 |
| 93 | cellular response to interferon-beta (GO:0035458) | 2.64926535 |
| 94 | muscle atrophy (GO:0014889) | 2.64332955 |
| 95 | retina layer formation (GO:0010842) | 2.63658935 |
| 96 | NAD biosynthetic process (GO:0009435) | 2.63252976 |
| 97 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.63194958 |
| 98 | renal tubule morphogenesis (GO:0061333) | 2.62242655 |
| 99 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.61213455 |
| 100 | pseudouridine synthesis (GO:0001522) | 2.61174419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 5.38563950 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.73248865 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.89890298 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.67278877 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.54479654 |
| 6 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.50294414 |
| 7 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.47012730 |
| 8 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.44701674 |
| 9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.36823621 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.24491632 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.22593326 |
| 12 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.06769949 |
| 13 | P300_19829295_ChIP-Seq_ESCs_Human | 2.05329588 |
| 14 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.04569845 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.04067924 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.97271397 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.94705575 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.93922382 |
| 19 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.91071852 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88749791 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.88238782 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.86887936 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.86751173 |
| 24 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.84263525 |
| 25 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.84263525 |
| 26 | GATA1_22025678_ChIP-Seq_K562_Human | 1.76862630 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.75572286 |
| 28 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.75518444 |
| 29 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.73191191 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.70691074 |
| 31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.67202539 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59511668 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50434811 |
| 34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.50173214 |
| 35 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.46016433 |
| 36 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44781861 |
| 37 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.43456009 |
| 38 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.42583222 |
| 39 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.41864213 |
| 40 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.39211820 |
| 41 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36681840 |
| 42 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36681840 |
| 43 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.35987097 |
| 44 | STAT3_23295773_ChIP-Seq_U87_Human | 1.34416137 |
| 45 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.34191496 |
| 46 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32690439 |
| 47 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31692696 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.31298633 |
| 49 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.30973589 |
| 50 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.30919096 |
| 51 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.30544601 |
| 52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.30245959 |
| 53 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29887791 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.29866769 |
| 55 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.28880182 |
| 56 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.26330182 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.25389640 |
| 58 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.22761571 |
| 59 | TCF4_23295773_ChIP-Seq_U87_Human | 1.20426734 |
| 60 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.19910517 |
| 61 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.19116903 |
| 62 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.18836820 |
| 63 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.18179813 |
| 64 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.18117415 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17422073 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15439801 |
| 67 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.14355383 |
| 68 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.14161765 |
| 69 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.12234147 |
| 70 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.10951990 |
| 71 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.09315844 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.09282345 |
| 73 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.08719565 |
| 74 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.08477009 |
| 75 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.08316917 |
| 76 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.07762992 |
| 77 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06732068 |
| 78 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.06675355 |
| 79 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.06608621 |
| 80 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.05670980 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.05144544 |
| 82 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.05144544 |
| 83 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03832319 |
| 84 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.02728930 |
| 85 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.02506396 |
| 86 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02272934 |
| 87 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.01973661 |
| 88 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.01877866 |
| 89 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01845988 |
| 90 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.99250143 |
| 91 | GATA3_26560356_Chip-Seq_TH2_Human | 0.99120207 |
| 92 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.98415553 |
| 93 | TP53_16413492_ChIP-PET_HCT116_Human | 0.98411587 |
| 94 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.98039176 |
| 95 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97994382 |
| 96 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97994382 |
| 97 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.97101182 |
| 98 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.96986531 |
| 99 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.96380249 |
| 100 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.94888628 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003950_abnormal_plasma_membrane | 5.08327626 |
| 2 | MP0002102_abnormal_ear_morphology | 4.49884146 |
| 3 | MP0002163_abnormal_gland_morphology | 3.88046374 |
| 4 | MP0002653_abnormal_ependyma_morphology | 3.29694389 |
| 5 | MP0002876_abnormal_thyroid_physiology | 3.15656895 |
| 6 | MP0005379_endocrine/exocrine_gland_phen | 2.85708457 |
| 7 | MP0001986_abnormal_taste_sensitivity | 2.80749292 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.57055101 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.51081222 |
| 10 | MP0004142_abnormal_muscle_tone | 2.43356238 |
| 11 | MP0008872_abnormal_physiological_respon | 2.39463452 |
| 12 | MP0001984_abnormal_olfaction | 2.34229875 |
| 13 | MP0003646_muscle_fatigue | 2.13178213 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.12996383 |
| 15 | MP0003195_calcinosis | 2.02469520 |
| 16 | MP0008877_abnormal_DNA_methylation | 2.02142173 |
| 17 | MP0009780_abnormal_chondrocyte_physiolo | 1.96994968 |
| 18 | MP0000427_abnormal_hair_cycle | 1.95326364 |
| 19 | MP0003122_maternal_imprinting | 1.94524936 |
| 20 | MP0004145_abnormal_muscle_electrophysio | 1.90495567 |
| 21 | MP0001440_abnormal_grooming_behavior | 1.90092509 |
| 22 | MP0002938_white_spotting | 1.74958713 |
| 23 | MP0001661_extended_life_span | 1.72108850 |
| 24 | MP0009046_muscle_twitch | 1.59933936 |
| 25 | MP0000749_muscle_degeneration | 1.57365551 |
| 26 | MP0003121_genomic_imprinting | 1.52057457 |
| 27 | MP0005394_taste/olfaction_phenotype | 1.49913678 |
| 28 | MP0005499_abnormal_olfactory_system | 1.49913678 |
| 29 | MP0008789_abnormal_olfactory_epithelium | 1.46572417 |
| 30 | MP0001919_abnormal_reproductive_system | 1.45779328 |
| 31 | MP0000685_abnormal_immune_system | 1.45770029 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.44311140 |
| 33 | MP0000383_abnormal_hair_follicle | 1.38760549 |
| 34 | MP0005389_reproductive_system_phenotype | 1.32599089 |
| 35 | MP0005670_abnormal_white_adipose | 1.30737216 |
| 36 | MP0002095_abnormal_skin_pigmentation | 1.29259611 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.24448640 |
| 38 | MP0002160_abnormal_reproductive_system | 1.23728541 |
| 39 | MP0006292_abnormal_olfactory_placode | 1.19776194 |
| 40 | MP0002138_abnormal_hepatobiliary_system | 1.19133640 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.18968172 |
| 42 | MP0006054_spinal_hemorrhage | 1.18089292 |
| 43 | MP0002928_abnormal_bile_duct | 1.13408849 |
| 44 | MP0005220_abnormal_exocrine_pancreas | 1.12153074 |
| 45 | MP0004147_increased_porphyrin_level | 1.09513544 |
| 46 | MP0006082_CNS_inflammation | 1.09502112 |
| 47 | MP0008875_abnormal_xenobiotic_pharmacok | 1.08532462 |
| 48 | MP0003186_abnormal_redox_activity | 1.05653510 |
| 49 | MP0005332_abnormal_amino_acid | 1.04331518 |
| 50 | MP0005646_abnormal_pituitary_gland | 1.03197684 |
| 51 | MP0003136_yellow_coat_color | 1.02965682 |
| 52 | MP0001293_anophthalmia | 1.01414861 |
| 53 | MP0009745_abnormal_behavioral_response | 0.99892772 |
| 54 | MP0003567_abnormal_fetal_cardiomyocyte | 0.97574043 |
| 55 | MP0003959_abnormal_lean_body | 0.97456632 |
| 56 | MP0004133_heterotaxia | 0.96695901 |
| 57 | MP0001486_abnormal_startle_reflex | 0.96297380 |
| 58 | MP0005084_abnormal_gallbladder_morpholo | 0.95606308 |
| 59 | MP0006072_abnormal_retinal_apoptosis | 0.93952615 |
| 60 | MP0004043_abnormal_pH_regulation | 0.93411559 |
| 61 | MP0000538_abnormal_urinary_bladder | 0.91414132 |
| 62 | MP0001529_abnormal_vocalization | 0.91315307 |
| 63 | MP0002272_abnormal_nervous_system | 0.90486573 |
| 64 | MP0003119_abnormal_digestive_system | 0.90169999 |
| 65 | MP0000631_abnormal_neuroendocrine_gland | 0.90069769 |
| 66 | MP0002693_abnormal_pancreas_physiology | 0.89259695 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 0.89185856 |
| 68 | MP0001968_abnormal_touch/_nociception | 0.88523074 |
| 69 | MP0003868_abnormal_feces_composition | 0.88342323 |
| 70 | MP0004381_abnormal_hair_follicle | 0.87778372 |
| 71 | MP0000015_abnormal_ear_pigmentation | 0.86187965 |
| 72 | MP0003787_abnormal_imprinting | 0.82755374 |
| 73 | MP0010386_abnormal_urinary_bladder | 0.81797501 |
| 74 | MP0003183_abnormal_peptide_metabolism | 0.81765451 |
| 75 | MP0005448_abnormal_energy_balance | 0.80471970 |
| 76 | MP0004885_abnormal_endolymph | 0.79192605 |
| 77 | MP0005174_abnormal_tail_pigmentation | 0.78068553 |
| 78 | MP0008961_abnormal_basal_metabolism | 0.75816599 |
| 79 | MP0000230_abnormal_systemic_arterial | 0.75796908 |
| 80 | MP0003890_abnormal_embryonic-extraembry | 0.75412770 |
| 81 | MP0003011_delayed_dark_adaptation | 0.75193814 |
| 82 | MP0001485_abnormal_pinna_reflex | 0.75166690 |
| 83 | MP0002127_abnormal_cardiovascular_syste | 0.73067962 |
| 84 | MP0000026_abnormal_inner_ear | 0.72645265 |
| 85 | MP0005671_abnormal_response_to | 0.71399814 |
| 86 | MP0003283_abnormal_digestive_organ | 0.68537162 |
| 87 | MP0001764_abnormal_homeostasis | 0.67916802 |
| 88 | MP0002135_abnormal_kidney_morphology | 0.67697127 |
| 89 | MP0002734_abnormal_mechanical_nocicepti | 0.65238720 |
| 90 | MP0005410_abnormal_fertilization | 0.62812467 |
| 91 | MP0003866_abnormal_defecation | 0.62550495 |
| 92 | MP0000750_abnormal_muscle_regeneration | 0.62532753 |
| 93 | MP0002736_abnormal_nociception_after | 0.60529700 |
| 94 | MP0004215_abnormal_myocardial_fiber | 0.59606798 |
| 95 | MP0001756_abnormal_urination | 0.58991180 |
| 96 | MP0001664_abnormal_digestion | 0.58433771 |
| 97 | MP0001501_abnormal_sleep_pattern | 0.57769853 |
| 98 | MP0005266_abnormal_metabolism | 0.57412147 |
| 99 | MP0002067_abnormal_sensory_capabilities | 0.56372035 |
| 100 | MP0000569_abnormal_digit_pigmentation | 0.56248026 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic cysts (HP:0001737) | 3.99116601 |
| 2 | Type 2 muscle fiber atrophy (HP:0003554) | 3.97923770 |
| 3 | Calf muscle hypertrophy (HP:0008981) | 3.88092909 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 3.66599169 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 3.66599169 |
| 6 | Pancreatic fibrosis (HP:0100732) | 3.63621629 |
| 7 | Renal cortical cysts (HP:0000803) | 3.59942271 |
| 8 | Renal salt wasting (HP:0000127) | 3.59344372 |
| 9 | Abnormality of the renal cortex (HP:0011035) | 3.56945002 |
| 10 | Polyuria (HP:0000103) | 3.51809579 |
| 11 | Hypomagnesemia (HP:0002917) | 3.44561523 |
| 12 | Occipital encephalocele (HP:0002085) | 3.34190330 |
| 13 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.32802403 |
| 14 | Muscle fiber atrophy (HP:0100295) | 3.19269101 |
| 15 | True hermaphroditism (HP:0010459) | 3.19135313 |
| 16 | Abnormal pancreas size (HP:0012094) | 3.02749328 |
| 17 | Acute encephalopathy (HP:0006846) | 3.00448157 |
| 18 | Acute necrotizing encephalopathy (HP:0006965) | 2.92908687 |
| 19 | Medial flaring of the eyebrow (HP:0010747) | 2.80453003 |
| 20 | Alkalosis (HP:0001948) | 2.78652384 |
| 21 | Abnormal urine output (HP:0012590) | 2.77496605 |
| 22 | Chronic hepatic failure (HP:0100626) | 2.76834130 |
| 23 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.76153965 |
| 24 | Febrile seizures (HP:0002373) | 2.74945985 |
| 25 | Metaphyseal dysplasia (HP:0100255) | 2.68174215 |
| 26 | Nephronophthisis (HP:0000090) | 2.66334689 |
| 27 | Exercise-induced muscle cramps (HP:0003710) | 2.59722956 |
| 28 | Abnormality of renal excretion (HP:0011036) | 2.59585457 |
| 29 | 3-Methylglutaconic aciduria (HP:0003535) | 2.59520112 |
| 30 | Hepatocellular necrosis (HP:0001404) | 2.56295648 |
| 31 | Congenital stationary night blindness (HP:0007642) | 2.55937587 |
| 32 | Progressive macrocephaly (HP:0004481) | 2.53962832 |
| 33 | Abnormality of the renal medulla (HP:0100957) | 2.53241106 |
| 34 | Abnormality of the labia minora (HP:0012880) | 2.53002237 |
| 35 | Autoimmune thrombocytopenia (HP:0001973) | 2.52891736 |
| 36 | Abnormality of magnesium homeostasis (HP:0004921) | 2.49992336 |
| 37 | Mitochondrial inheritance (HP:0001427) | 2.48786626 |
| 38 | Increased circulating renin level (HP:0000848) | 2.47486751 |
| 39 | Metabolic alkalosis (HP:0200114) | 2.45182939 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.44944799 |
| 41 | Abnormality of alanine metabolism (HP:0010916) | 2.44944799 |
| 42 | Hyperalaninemia (HP:0003348) | 2.44944799 |
| 43 | Poor suck (HP:0002033) | 2.42653288 |
| 44 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.40626155 |
| 45 | Attenuation of retinal blood vessels (HP:0007843) | 2.40299217 |
| 46 | Hepatic necrosis (HP:0002605) | 2.39709692 |
| 47 | Cystic liver disease (HP:0006706) | 2.38327933 |
| 48 | Increased corneal curvature (HP:0100692) | 2.37287095 |
| 49 | Keratoconus (HP:0000563) | 2.37287095 |
| 50 | Increased CSF lactate (HP:0002490) | 2.36690902 |
| 51 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.36299863 |
| 52 | Polyphagia (HP:0002591) | 2.33946241 |
| 53 | Tubular atrophy (HP:0000092) | 2.32786864 |
| 54 | Abnormal number of erythroid precursors (HP:0012131) | 2.32422888 |
| 55 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.31732192 |
| 56 | Hyperglycinuria (HP:0003108) | 2.27186839 |
| 57 | Abolished electroretinogram (ERG) (HP:0000550) | 2.27082082 |
| 58 | Sclerocornea (HP:0000647) | 2.25702645 |
| 59 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.25515528 |
| 60 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.22617589 |
| 61 | Hyperglycinemia (HP:0002154) | 2.21256221 |
| 62 | Abnormality of proline metabolism (HP:0010907) | 2.18995051 |
| 63 | Hydroxyprolinuria (HP:0003080) | 2.18995051 |
| 64 | Hyponatremia (HP:0002902) | 2.16187720 |
| 65 | Optic disc pallor (HP:0000543) | 2.13472156 |
| 66 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.11096461 |
| 67 | Hypokalemic alkalosis (HP:0001949) | 2.09065910 |
| 68 | Gait imbalance (HP:0002141) | 2.08114701 |
| 69 | Abnormal ciliary motility (HP:0012262) | 2.05485133 |
| 70 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.02491469 |
| 71 | Congenital primary aphakia (HP:0007707) | 2.01965827 |
| 72 | Chorioretinal atrophy (HP:0000533) | 2.00859770 |
| 73 | Pigmentary retinal degeneration (HP:0001146) | 1.97873971 |
| 74 | Respiratory failure (HP:0002878) | 1.97398557 |
| 75 | Rhinitis (HP:0012384) | 1.97381974 |
| 76 | Postaxial foot polydactyly (HP:0001830) | 1.95750011 |
| 77 | Absent/shortened dynein arms (HP:0200106) | 1.93931206 |
| 78 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.93931206 |
| 79 | Shawl scrotum (HP:0000049) | 1.93888559 |
| 80 | CNS demyelination (HP:0007305) | 1.93554267 |
| 81 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.93340086 |
| 82 | Increased serum lactate (HP:0002151) | 1.90513597 |
| 83 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.86011452 |
| 84 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.85147567 |
| 85 | Anencephaly (HP:0002323) | 1.84796948 |
| 86 | Large eyes (HP:0001090) | 1.82572883 |
| 87 | Hypoplasia of the fovea (HP:0007750) | 1.80169978 |
| 88 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.80169978 |
| 89 | Narrow forehead (HP:0000341) | 1.80086803 |
| 90 | Abnormality of renal resorption (HP:0011038) | 1.78846654 |
| 91 | Asplenia (HP:0001746) | 1.78536551 |
| 92 | Increased serum pyruvate (HP:0003542) | 1.78514850 |
| 93 | Oligodactyly (hands) (HP:0001180) | 1.77949336 |
| 94 | Limb hypertonia (HP:0002509) | 1.75958726 |
| 95 | Type II lissencephaly (HP:0007260) | 1.75102107 |
| 96 | Hyperactive renin-angiotensin system (HP:0000841) | 1.74045588 |
| 97 | Papilledema (HP:0001085) | 1.73877401 |
| 98 | Widely spaced teeth (HP:0000687) | 1.73629535 |
| 99 | Hypoplasia of the thymus (HP:0000778) | 1.73456456 |
| 100 | Genital tract atresia (HP:0001827) | 1.73012568 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 3.91042838 |
| 2 | TAOK3 | 3.78121782 |
| 3 | MAP4K2 | 3.75537917 |
| 4 | CDK8 | 3.69404629 |
| 5 | FRK | 3.51613246 |
| 6 | WNK4 | 3.13371266 |
| 7 | BMPR1B | 2.70804996 |
| 8 | STK39 | 2.39818916 |
| 9 | NUAK1 | 2.35334147 |
| 10 | VRK2 | 2.13604260 |
| 11 | INSRR | 2.12036912 |
| 12 | MAPKAPK5 | 2.03490769 |
| 13 | BCR | 1.94931657 |
| 14 | TAF1 | 1.86673760 |
| 15 | PIK3CA | 1.82690059 |
| 16 | EIF2AK3 | 1.63271613 |
| 17 | GRK7 | 1.55585788 |
| 18 | GRK1 | 1.49132008 |
| 19 | TRIM28 | 1.47960886 |
| 20 | ADRBK2 | 1.46842670 |
| 21 | TSSK6 | 1.46643193 |
| 22 | AKT3 | 1.44688423 |
| 23 | DAPK2 | 1.41131440 |
| 24 | MELK | 1.40465692 |
| 25 | MUSK | 1.30872635 |
| 26 | TGFBR1 | 1.23445934 |
| 27 | TLK1 | 1.12815091 |
| 28 | CDK9 | 1.08177009 |
| 29 | TEC | 1.06013053 |
| 30 | DMPK | 1.05513344 |
| 31 | MOS | 1.04946102 |
| 32 | EPHA3 | 1.04486247 |
| 33 | DYRK2 | 1.02313933 |
| 34 | PRKCE | 1.01059938 |
| 35 | VRK1 | 0.99472189 |
| 36 | MAP3K12 | 0.98728594 |
| 37 | MAP3K2 | 0.97202770 |
| 38 | BCKDK | 0.96690995 |
| 39 | WNK1 | 0.96604833 |
| 40 | TXK | 0.95972381 |
| 41 | IKBKB | 0.95283691 |
| 42 | TNK2 | 0.90734955 |
| 43 | ACVR1B | 0.90183666 |
| 44 | PLK2 | 0.89339691 |
| 45 | KIT | 0.85992193 |
| 46 | FGFR2 | 0.82216645 |
| 47 | PASK | 0.79451741 |
| 48 | PIK3CG | 0.74947279 |
| 49 | ADRBK1 | 0.73873337 |
| 50 | STK38L | 0.72344768 |
| 51 | PDK2 | 0.72026191 |
| 52 | PAK3 | 0.71462812 |
| 53 | PLK3 | 0.69932348 |
| 54 | PRKCQ | 0.67334448 |
| 55 | WNK3 | 0.66556949 |
| 56 | MKNK2 | 0.66148770 |
| 57 | MAP3K7 | 0.65939857 |
| 58 | OXSR1 | 0.62968089 |
| 59 | ABL2 | 0.62154032 |
| 60 | RPS6KA5 | 0.57239269 |
| 61 | CLK1 | 0.57113064 |
| 62 | ZAK | 0.56825724 |
| 63 | PRKACB | 0.56217270 |
| 64 | PAK6 | 0.55887841 |
| 65 | PINK1 | 0.55174667 |
| 66 | PHKG2 | 0.55029308 |
| 67 | PHKG1 | 0.55029308 |
| 68 | TGFBR2 | 0.54831442 |
| 69 | GRK5 | 0.54711674 |
| 70 | NTRK2 | 0.54214812 |
| 71 | MAPK13 | 0.53842324 |
| 72 | CCNB1 | 0.53827305 |
| 73 | CASK | 0.53191908 |
| 74 | SIK3 | 0.53188833 |
| 75 | MAP3K3 | 0.52300308 |
| 76 | FER | 0.49850587 |
| 77 | EIF2AK1 | 0.48229711 |
| 78 | PRKG1 | 0.48209396 |
| 79 | EIF2AK2 | 0.47454238 |
| 80 | PRKCG | 0.45241458 |
| 81 | PRKACA | 0.42863272 |
| 82 | MARK1 | 0.42745274 |
| 83 | NLK | 0.42105730 |
| 84 | MAP3K4 | 0.42077667 |
| 85 | KSR1 | 0.39997966 |
| 86 | CAMK2D | 0.39903014 |
| 87 | TNIK | 0.37350856 |
| 88 | CSNK1D | 0.37212818 |
| 89 | STK11 | 0.35804841 |
| 90 | LMTK2 | 0.35480073 |
| 91 | PRKCI | 0.35184321 |
| 92 | CAMK2A | 0.34983116 |
| 93 | DAPK3 | 0.34661206 |
| 94 | PIM2 | 0.31678144 |
| 95 | CDK3 | 0.31141102 |
| 96 | CSNK1A1 | 0.30853543 |
| 97 | PTK2B | 0.30537383 |
| 98 | RPS6KA4 | 0.30309002 |
| 99 | MAP2K6 | 0.29844614 |
| 100 | PRKCA | 0.29249206 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.17490460 |
| 2 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.83794789 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.72033407 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.45637472 |
| 5 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.40683498 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.37973026 |
| 7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.26196936 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.23362514 |
| 9 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.19882146 |
| 10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.12334118 |
| 11 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.99678118 |
| 12 | Parkinsons disease_Homo sapiens_hsa05012 | 1.95841580 |
| 13 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.92745095 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.91908127 |
| 15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.86105334 |
| 16 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.83291351 |
| 17 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.82860552 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.80814002 |
| 19 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.78828761 |
| 20 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.67816492 |
| 21 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.67081981 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.65996977 |
| 23 | RNA polymerase_Homo sapiens_hsa03020 | 1.64968525 |
| 24 | Proteasome_Homo sapiens_hsa03050 | 1.64060700 |
| 25 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.53806834 |
| 26 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.51872857 |
| 27 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.51264839 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.50140587 |
| 29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.49616050 |
| 30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.40403958 |
| 31 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.37300205 |
| 32 | Huntingtons disease_Homo sapiens_hsa05016 | 1.34460259 |
| 33 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.33587223 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.31360335 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.28971488 |
| 36 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.25689728 |
| 37 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.24067915 |
| 38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21398397 |
| 39 | Nicotine addiction_Homo sapiens_hsa05033 | 1.20331465 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.18336877 |
| 41 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.17174812 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15413413 |
| 43 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.15335339 |
| 44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14499541 |
| 45 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.13306889 |
| 46 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.11960812 |
| 47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.09891679 |
| 48 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.08528474 |
| 49 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.06431902 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.03211745 |
| 51 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.01641702 |
| 52 | Homologous recombination_Homo sapiens_hsa03440 | 1.00615180 |
| 53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.99822513 |
| 54 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.98566688 |
| 55 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.96123070 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.94533803 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.91619206 |
| 58 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.87693706 |
| 59 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.85834639 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.85750705 |
| 61 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.80622057 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.80412380 |
| 63 | Ribosome_Homo sapiens_hsa03010 | 0.78987243 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78573418 |
| 65 | Histidine metabolism_Homo sapiens_hsa00340 | 0.78133334 |
| 66 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.76246721 |
| 67 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.73903023 |
| 68 | Insulin secretion_Homo sapiens_hsa04911 | 0.72734093 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68789810 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68588106 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67480674 |
| 72 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.66589017 |
| 73 | ABC transporters_Homo sapiens_hsa02010 | 0.64848515 |
| 74 | Asthma_Homo sapiens_hsa05310 | 0.59952969 |
| 75 | GABAergic synapse_Homo sapiens_hsa04727 | 0.58513105 |
| 76 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.58506849 |
| 77 | Lysine degradation_Homo sapiens_hsa00310 | 0.58254746 |
| 78 | Sulfur relay system_Homo sapiens_hsa04122 | 0.57429780 |
| 79 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.56941118 |
| 80 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.54974498 |
| 81 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.54256839 |
| 82 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53733677 |
| 83 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.52866519 |
| 84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.48424488 |
| 85 | Purine metabolism_Homo sapiens_hsa00230 | 0.47822418 |
| 86 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.43729662 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43605279 |
| 88 | Mismatch repair_Homo sapiens_hsa03430 | 0.43212562 |
| 89 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.42158499 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.42075541 |
| 91 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40511896 |
| 92 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.40098148 |
| 93 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.38399798 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.37205893 |
| 95 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.36645312 |
| 96 | Circadian rhythm_Homo sapiens_hsa04710 | 0.35319467 |
| 97 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.34438786 |
| 98 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.32973105 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29839212 |
| 100 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.28502738 |

