SERF2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.87615351
2viral transcription (GO:0019083)7.72335393
3ribosomal small subunit biogenesis (GO:0042274)7.46131098
4ATP synthesis coupled proton transport (GO:0015986)7.43208077
5energy coupled proton transport, down electrochemical gradient (GO:0015985)7.43208077
6translational termination (GO:0006415)7.39031529
7ribosomal small subunit assembly (GO:0000028)6.82551043
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.74143966
9cotranslational protein targeting to membrane (GO:0006613)6.71897586
10protein targeting to ER (GO:0045047)6.70007551
11establishment of protein localization to endoplasmic reticulum (GO:0072599)6.42769637
12protein localization to endoplasmic reticulum (GO:0070972)6.30456284
13translational elongation (GO:0006414)6.12058890
14mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.92906036
15viral life cycle (GO:0019058)5.87069689
16respiratory electron transport chain (GO:0022904)5.75058028
17cellular protein complex disassembly (GO:0043624)5.69953214
18electron transport chain (GO:0022900)5.59001806
19translational initiation (GO:0006413)5.35691410
20nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.29222963
21maturation of SSU-rRNA (GO:0030490)5.24387419
22ribosomal large subunit biogenesis (GO:0042273)4.76590405
23protein complex disassembly (GO:0043241)4.72801465
24protein neddylation (GO:0045116)4.66991550
25protein targeting to membrane (GO:0006612)4.63928202
26translation (GO:0006412)4.62735015
27macromolecular complex disassembly (GO:0032984)4.44802979
28deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.26786652
29proteasome assembly (GO:0043248)4.24321430
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.81226223
31regulation of mitochondrial translation (GO:0070129)3.76580146
32antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.70146228
33cytochrome complex assembly (GO:0017004)3.64748288
34termination of RNA polymerase III transcription (GO:0006386)3.58980875
35transcription elongation from RNA polymerase III promoter (GO:0006385)3.58980875
36negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.56727615
37inner mitochondrial membrane organization (GO:0007007)3.55904269
38nuclear-transcribed mRNA catabolic process (GO:0000956)3.51386664
39ATP biosynthetic process (GO:0006754)3.50515596
40purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.48610326
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.43224016
42GTP biosynthetic process (GO:0006183)3.41941880
43hydrogen ion transmembrane transport (GO:1902600)3.41611734
44chaperone-mediated protein transport (GO:0072321)3.40843132
45negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.39926991
46negative regulation of ligase activity (GO:0051352)3.39926991
47purine nucleoside triphosphate biosynthetic process (GO:0009145)3.39924006
48respiratory chain complex IV assembly (GO:0008535)3.34967315
49mRNA catabolic process (GO:0006402)3.32526803
50mitochondrial respiratory chain complex I assembly (GO:0032981)3.32504234
51NADH dehydrogenase complex assembly (GO:0010257)3.32504234
52mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.32504234
53ribonucleoprotein complex biogenesis (GO:0022613)3.32159436
54DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.31845843
55establishment of protein localization to membrane (GO:0090150)3.27992346
56regulation of cellular amino acid metabolic process (GO:0006521)3.26505069
57protein complex biogenesis (GO:0070271)3.26213903
58positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.24497829
59rRNA modification (GO:0000154)3.22375754
60signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.20315207
61intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.20315207
62signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.17165239
63signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.17165239
64signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.17165239
65response to interferon-beta (GO:0035456)3.16599963
66protein targeting (GO:0006605)3.14538863
67signal transduction involved in DNA integrity checkpoint (GO:0072401)3.11813641
68signal transduction involved in DNA damage checkpoint (GO:0072422)3.11813641
69ribonucleoside triphosphate biosynthetic process (GO:0009201)3.10335906
70cytidine catabolic process (GO:0006216)3.08381311
71cytidine deamination (GO:0009972)3.08381311
72cytidine metabolic process (GO:0046087)3.08381311
73anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.08132994
74regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.07483245
75signal transduction involved in cell cycle checkpoint (GO:0072395)3.06047933
76aerobic respiration (GO:0009060)3.03448391
77GDP-mannose metabolic process (GO:0019673)3.02494055
78oxidative phosphorylation (GO:0006119)3.01972899
79pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.01298041
80cellular component biogenesis (GO:0044085)3.00104924
81sequestering of actin monomers (GO:0042989)2.98273980
827-methylguanosine mRNA capping (GO:0006370)2.97872751
83UTP biosynthetic process (GO:0006228)2.95998597
84RNA catabolic process (GO:0006401)2.95725545
85mitochondrial respiratory chain complex assembly (GO:0033108)2.95679035
86proton transport (GO:0015992)2.95634226
87L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.94627534
88platelet dense granule organization (GO:0060155)2.93512394
89antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.92284114
90protein targeting to mitochondrion (GO:0006626)2.90819051
917-methylguanosine RNA capping (GO:0009452)2.90791629
92RNA capping (GO:0036260)2.90791629
93establishment of protein localization to mitochondrion (GO:0072655)2.87694178
94hydrogen transport (GO:0006818)2.87480272
95regulation of oxidative phosphorylation (GO:0002082)2.84099617
96deoxyribonucleotide catabolic process (GO:0009264)2.83902648
97neutrophil activation involved in immune response (GO:0002283)2.83485295
98deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.83410647
99purine nucleotide salvage (GO:0032261)2.80830898
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.79214175
101cellular response to interferon-beta (GO:0035458)2.77262158
102muscle filament sliding (GO:0030049)2.76159086
103actin-myosin filament sliding (GO:0033275)2.76159086
104purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.75853537
105purine nucleoside monophosphate biosynthetic process (GO:0009127)2.75853537
106establishment of protein localization to organelle (GO:0072594)2.75540690
107DNA deamination (GO:0045006)2.75232140
108hydrogen peroxide catabolic process (GO:0042744)2.74957976
109positive regulation of ligase activity (GO:0051351)2.74318256
110rRNA processing (GO:0006364)2.73594443
111protein maturation by protein folding (GO:0022417)2.72718230
112mitochondrial transport (GO:0006839)2.71831478
113aldehyde catabolic process (GO:0046185)2.64856990
114nucleoside triphosphate biosynthetic process (GO:0009142)2.64105388
115protein localization to mitochondrion (GO:0070585)2.62185459
116formation of translation preinitiation complex (GO:0001731)2.62169473
117heart process (GO:0003015)2.61908435
118heart contraction (GO:0060047)2.61908435
119regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.61765426
120negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.60437006
121positive regulation of cell cycle arrest (GO:0071158)2.59932788
122sarcomere organization (GO:0045214)2.58701837
123rRNA metabolic process (GO:0016072)2.58010519

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.65743713
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.07482378
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.04813554
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.67320854
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.54059438
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46518530
7* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.42478547
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.37976827
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.32897994
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.23933609
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.23770869
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.12521790
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.87123139
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.78308705
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42729533
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.42399738
17CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.38320863
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33202878
19* XRN2_22483619_ChIP-Seq_HELA_Human2.30707602
20DCP1A_22483619_ChIP-Seq_HELA_Human2.29899324
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.28744367
22TP63_17297297_ChIP-ChIP_HaCaT_Human2.12715141
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.11360224
24VDR_23849224_ChIP-Seq_CD4+_Human2.03736011
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.02247874
26MYC_19030024_ChIP-ChIP_MESCs_Mouse2.00958558
27ELK1_22589737_ChIP-Seq_MCF10A_Human1.97032429
28CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.95207024
29PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.91928896
30* SRF_21415370_ChIP-Seq_HL-1_Mouse1.89212658
31ELK1_19687146_ChIP-ChIP_HELA_Human1.85097394
32CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.83678548
33TTF2_22483619_ChIP-Seq_HELA_Human1.79640470
34IRF8_21731497_ChIP-ChIP_J774_Mouse1.77301608
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.67854074
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.63102612
37TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.60435311
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59705171
39ELF1_17652178_ChIP-ChIP_JURKAT_Human1.59515779
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.54113373
41YY1_21170310_ChIP-Seq_MESCs_Mouse1.53850540
42GABP_19822575_ChIP-Seq_HepG2_Human1.53197234
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.50886723
44FOXP3_21729870_ChIP-Seq_TREG_Human1.46152655
45* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43266521
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43259536
47RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.42278214
48THAP11_20581084_ChIP-Seq_MESCs_Mouse1.41037704
49RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41001958
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38342660
51TRIM28_21343339_ChIP-Seq_HEK293_Human1.26888852
52* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.26084670
53HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.25324250
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24535438
55CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.24148525
56* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24116866
57HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.22170156
58ELF1_20517297_ChIP-Seq_JURKAT_Human1.22105380
59SPI1_23547873_ChIP-Seq_NB4_Human1.21957120
60NANOG_18555785_ChIP-Seq_MESCs_Mouse1.21804054
61ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.21221757
62* ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.19955843
63LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19171135
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16122294
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14406342
66NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.13567845
67BCL6_27268052_Chip-Seq_Bcells_Human1.13296056
68STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12487365
69PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10094428
70IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10015068
71OCT4_18692474_ChIP-Seq_MEFs_Mouse1.07914597
72SRY_22984422_ChIP-ChIP_TESTIS_Rat1.07309334
73TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05844463
74STAT1_20625510_ChIP-Seq_HELA_Human1.05689960
75KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04521787
76SOX2_18692474_ChIP-Seq_MEFs_Mouse1.03359592
77SOX17_20123909_ChIP-Seq_XEN_Mouse1.03184721
78TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03158643
79CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02893103
80IRF8_22096565_ChIP-ChIP_GC-B_Human1.02304761
81ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.01920529
82DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01581963
83FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01049573
84POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.99909418
85TET1_21451524_ChIP-Seq_MESCs_Mouse0.99610021
86KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97524334
87ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.97230240
88MYC_18940864_ChIP-ChIP_HL60_Human0.96325343
89SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96102045
90PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.95941813
91CTCF_18555785_ChIP-Seq_MESCs_Mouse0.94686511
92POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.93383974
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.92613298
94* TFEB_21752829_ChIP-Seq_HELA_Human0.92269710
95* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92185930
96* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.92142737
97BCOR_27268052_Chip-Seq_Bcells_Human0.92104213
98P300_27268052_Chip-Seq_Bcells_Human0.92010695
99* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90811052
100MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.90411974
101ERG_20517297_ChIP-Seq_VCAP_Human0.88143709
102VDR_24763502_ChIP-Seq_THP-1_Human0.87608279
103CTCF_20526341_ChIP-Seq_ESCs_Human0.87576150
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.87338035
105CTCF_26484167_Chip-Seq_Bcells_Mouse0.86992758
106FOXP1_21924763_ChIP-Seq_HESCs_Human0.86806460
107IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.86687307
108TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85505315
109STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85186029
110GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.84995143
111RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.84931307
112CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84573325
113MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.84080177
114PU.1_20513432_ChIP-Seq_Bcells_Mouse0.83851477
115YY1_22570637_ChIP-Seq_MALME-3M_Human0.83712875
116MAF_26560356_Chip-Seq_TH2_Human0.83152242
117EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.82681076
118STAT4_19710469_ChIP-ChIP_TH1__Mouse0.82052173
119VDR_21846776_ChIP-Seq_THP-1_Human0.81958637
120KDM5A_27292631_Chip-Seq_BREAST_Human0.81129846
121RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.81018210
122SMC3_22415368_ChIP-Seq_MEFs_Mouse0.80787711
123TBX5_21415370_ChIP-Seq_HL-1_Mouse0.80764644
124ZNF263_19887448_ChIP-Seq_K562_Human0.79036686
125KLF4_18555785_ChIP-Seq_MESCs_Mouse0.78860341
126ELK3_25401928_ChIP-Seq_HUVEC_Human0.78297323

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.36091313
2MP0008438_abnormal_cutaneous_collagen3.81511945
3MP0002837_dystrophic_cardiac_calcinosis3.10957947
4MP0000750_abnormal_muscle_regeneration2.45175729
5MP0005464_abnormal_platelet_physiology2.39554744
6MP0004084_abnormal_cardiac_muscle2.34306063
7MP0000749_muscle_degeneration2.23383887
8MP0005451_abnormal_body_composition2.21108075
9MP0002139_abnormal_hepatobiliary_system2.17213957
10MP0003646_muscle_fatigue2.10809049
11MP0003186_abnormal_redox_activity2.10438004
12MP0003950_abnormal_plasma_membrane2.07253289
13MP0005058_abnormal_lysosome_morphology1.96119227
14MP0002148_abnormal_hypersensitivity_rea1.89623709
15MP0005330_cardiomyopathy1.84463070
16MP0005084_abnormal_gallbladder_morpholo1.77924332
17MP0003724_increased_susceptibility_to1.77701689
18MP0000343_altered_response_to1.76122850
19MP0006082_CNS_inflammation1.74381980
20MP0009333_abnormal_splenocyte_physiolog1.73664654
21MP0001542_abnormal_bone_strength1.73061027
22MP0003693_abnormal_embryo_hatching1.71392095
23MP0004036_abnormal_muscle_relaxation1.68875419
24MP0000751_myopathy1.68397699
25MP0006036_abnormal_mitochondrial_physio1.64951962
26MP0008875_abnormal_xenobiotic_pharmacok1.62892977
27MP0003718_maternal_effect1.53769873
28MP0009785_altered_susceptibility_to1.52984104
29MP0004957_abnormal_blastocyst_morpholog1.48690495
30MP0001727_abnormal_embryo_implantation1.48597172
31MP0003786_premature_aging1.47029478
32MP0004019_abnormal_vitamin_homeostasis1.45570575
33MP0005408_hypopigmentation1.44205854
34MP0001800_abnormal_humoral_immune1.43652699
35MP0001845_abnormal_inflammatory_respons1.41971550
36MP0001873_stomach_inflammation1.41814493
37MP0002295_abnormal_pulmonary_circulatio1.40905792
38MP0005275_abnormal_skin_tensile1.39233024
39MP0005365_abnormal_bile_salt1.39206669
40MP0001835_abnormal_antigen_presentation1.38463392
41MP0003436_decreased_susceptibility_to1.37930113
42MP0003303_peritoneal_inflammation1.37348845
43MP0003221_abnormal_cardiomyocyte_apopto1.36550113
44MP0003806_abnormal_nucleotide_metabolis1.36385222
45MP0003828_pulmonary_edema1.35840086
46MP0005503_abnormal_tendon_morphology1.34185216
47MP0005000_abnormal_immune_tolerance1.32686654
48MP0005075_abnormal_melanosome_morpholog1.29793780
49MP0002933_joint_inflammation1.29686408
50MP0005025_abnormal_response_to1.28146402
51MP0008932_abnormal_embryonic_tissue1.27289252
52MP0010155_abnormal_intestine_physiology1.23450346
53MP0001764_abnormal_homeostasis1.22334533
54MP0004185_abnormal_adipocyte_glucose1.21073413
55MP0002106_abnormal_muscle_physiology1.21014532
56MP0004510_myositis1.20830314
57MP0005332_abnormal_amino_acid1.20773073
58MP0001544_abnormal_cardiovascular_syste1.20442852
59MP0005385_cardiovascular_system_phenoty1.20442852
60MP0003279_aneurysm1.20379093
61MP0004272_abnormal_basement_membrane1.20137071
62MP0005636_abnormal_mineral_homeostasis1.17257211
63MP0003075_altered_response_to1.15999532
64MP0002972_abnormal_cardiac_muscle1.14503501
65MP0002419_abnormal_innate_immunity1.14318606
66MP0001958_emphysema1.13772954
67MP0003638_abnormal_response/metabolism_1.13729573
68MP0009643_abnormal_urine_homeostasis1.13241855
69MP0004087_abnormal_muscle_fiber1.12222980
70MP0005083_abnormal_biliary_tract1.11666792
71MP0000858_altered_metastatic_potential1.10818274
72MP0001533_abnormal_skeleton_physiology1.09924186
73MP0005257_abnormal_intraocular_pressure1.07990696
74MP0002163_abnormal_gland_morphology1.07874674
75MP0002653_abnormal_ependyma_morphology1.06928879
76MP0005085_abnormal_gallbladder_physiolo1.05278309
77MP0000716_abnormal_immune_system1.05227450
78MP0003315_abnormal_perineum_morphology1.04920839
79MP0009763_increased_sensitivity_to1.04666987
80MP0002254_reproductive_system_inflammat1.04663199
81MP0003866_abnormal_defecation1.04196956
82MP0000490_abnormal_crypts_of1.03240861
83MP0004215_abnormal_myocardial_fiber1.03090545
84MP0002398_abnormal_bone_marrow1.02206337
85MP0000372_irregular_coat_pigmentation1.01777405
86MP0005360_urolithiasis1.00890614
87MP0009764_decreased_sensitivity_to1.00736402
88MP0008995_early_reproductive_senescence1.00394418
89MP0002876_abnormal_thyroid_physiology1.00376989
90MP0002429_abnormal_blood_cell1.00224641
91MP0005410_abnormal_fertilization1.00172811
92MP0005379_endocrine/exocrine_gland_phen0.99790267
93MP0003136_yellow_coat_color0.99668551
94MP0001881_abnormal_mammary_gland0.99276589
95MP0003137_abnormal_impulse_conducting0.97815163
96MP0005319_abnormal_enzyme/_coenzyme0.97762407
97MP0002405_respiratory_system_inflammati0.96734367
98MP0008058_abnormal_DNA_repair0.95848390
99MP0000689_abnormal_spleen_morphology0.95789272
100MP0003448_altered_tumor_morphology0.95458211
101MP0006138_congestive_heart_failure0.95158372
102MP0009840_abnormal_foam_cell0.94955699
103MP0005369_muscle_phenotype0.94385805
104MP0001756_abnormal_urination0.93547187
105MP0005165_increased_susceptibility_to0.91746348
106MP0005164_abnormal_response_to0.91163180
107MP0003567_abnormal_fetal_cardiomyocyte0.90820940
108MP0002132_abnormal_respiratory_system0.90735906
109MP0001905_abnormal_dopamine_level0.90310301
110MP0002452_abnormal_antigen_presenting0.90218702
111MP0008775_abnormal_heart_ventricle0.89503071
112MP0001663_abnormal_digestive_system0.89414778
113MP0000685_abnormal_immune_system0.89342908
114MP0002722_abnormal_immune_system0.88795735
115MP0005387_immune_system_phenotype0.88722201
116MP0001790_abnormal_immune_system0.88722201
117MP0000759_abnormal_skeletal_muscle0.87931468
118MP0001853_heart_inflammation0.87268128
119MP0004145_abnormal_muscle_electrophysio0.87042052
120MP0000920_abnormal_myelination0.86716924
121MP0002723_abnormal_immune_serum0.84611888
122MP0005620_abnormal_muscle_contractility0.83448262
123MP0003566_abnormal_cell_adhesion0.83021398
124MP0003011_delayed_dark_adaptation0.82937627
125MP0003077_abnormal_cell_cycle0.82545713
126MP0003191_abnormal_cellular_cholesterol0.82397678
127MP0008872_abnormal_physiological_respon0.82239741
128MP0006072_abnormal_retinal_apoptosis0.82063367
129MP0002693_abnormal_pancreas_physiology0.81380036
130MP0001243_abnormal_dermal_layer0.81232816
131MP0002277_abnormal_respiratory_mucosa0.81199112
132MP0000747_muscle_weakness0.80640987
133MP0002938_white_spotting0.80434105
134MP0008469_abnormal_protein_level0.79617292
135MP0008004_abnormal_stomach_pH0.79586426
136MP0005390_skeleton_phenotype0.79522928
137MP0006035_abnormal_mitochondrial_morpho0.79213498
138MP0003941_abnormal_skin_development0.78932840
139MP0003763_abnormal_thymus_physiology0.78478378
140MP0010630_abnormal_cardiac_muscle0.78442378
141MP0005645_abnormal_hypothalamus_physiol0.78355656
142MP0005310_abnormal_salivary_gland0.77426198
143MP0001879_abnormal_lymphatic_vessel0.75703274
144MP0001819_abnormal_immune_cell0.75438611
145MP0000358_abnormal_cell_content/0.75341742
146MP0010386_abnormal_urinary_bladder0.75300147
147MP0005584_abnormal_enzyme/coenzyme_acti0.74456342
148MP0001529_abnormal_vocalization0.74260282
149MP0002420_abnormal_adaptive_immunity0.74092246
150MP0004147_increased_porphyrin_level0.72896355
151MP0005166_decreased_susceptibility_to0.72432655
152MP0005671_abnormal_response_to0.70590199
153MP0001851_eye_inflammation0.69511103

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.53102880
2Mitochondrial inheritance (HP:0001427)5.11020524
3Abnormality of cells of the erythroid lineage (HP:0012130)4.99569800
4Abnormal mitochondria in muscle tissue (HP:0008316)4.93223726
5Increased hepatocellular lipid droplets (HP:0006565)4.68726590
6Acute encephalopathy (HP:0006846)4.52902205
7Progressive macrocephaly (HP:0004481)4.42176358
8Reticulocytopenia (HP:0001896)4.40577419
9Abnormal number of erythroid precursors (HP:0012131)4.39610019
10Hepatocellular necrosis (HP:0001404)4.33943839
11Lipid accumulation in hepatocytes (HP:0006561)4.30770628
12Renal Fanconi syndrome (HP:0001994)4.13057204
13Increased CSF lactate (HP:0002490)4.12588977
14Hepatic necrosis (HP:0002605)4.07908933
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.96798255
16Exertional dyspnea (HP:0002875)3.93860019
17Macrocytic anemia (HP:0001972)3.86495595
18Increased intramyocellular lipid droplets (HP:0012240)3.74232052
19Respiratory failure (HP:0002878)3.50811726
20Aplastic anemia (HP:0001915)3.49573105
21Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.47752861
22Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.45508158
23Decreased activity of mitochondrial respiratory chain (HP:0008972)3.45508158
24Increased serum pyruvate (HP:0003542)3.43505232
25Abnormality of glycolysis (HP:0004366)3.43505232
26Increased muscle lipid content (HP:0009058)3.39702300
27Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.39132761
28Exercise intolerance (HP:0003546)3.26238178
29Muscle fiber splitting (HP:0003555)3.25586594
30Pallor (HP:0000980)3.21164295
31Petechiae (HP:0000967)3.15221797
323-Methylglutaconic aciduria (HP:0003535)3.13222142
33Cerebral edema (HP:0002181)3.10038698
34Aplasia/Hypoplasia of the sacrum (HP:0008517)3.07118338
35Abnormal hemoglobin (HP:0011902)3.05235620
36Premature rupture of membranes (HP:0001788)2.94709957
37Generalized aminoaciduria (HP:0002909)2.89278257
38Parakeratosis (HP:0001036)2.87876163
39Vacuolated lymphocytes (HP:0001922)2.78614804
40Multiple enchondromatosis (HP:0005701)2.76576128
41Type I transferrin isoform profile (HP:0003642)2.73850309
42Respiratory difficulties (HP:0002880)2.69222026
43Lactic acidosis (HP:0003128)2.64209863
44Oral leukoplakia (HP:0002745)2.60226696
45Increased serum lactate (HP:0002151)2.57086120
46Ventricular tachycardia (HP:0004756)2.56821276
47Abnormality of glycolipid metabolism (HP:0010969)2.55846455
48Abnormality of liposaccharide metabolism (HP:0010968)2.55846455
49Abnormality of glycosphingolipid metabolism (HP:0004343)2.55846455
50Congenital ichthyosiform erythroderma (HP:0007431)2.48519618
51Leukodystrophy (HP:0002415)2.45425107
52Abnormality of renal resorption (HP:0011038)2.44924935
53Abnormality of dicarboxylic acid metabolism (HP:0010995)2.44173977
54Dicarboxylic aciduria (HP:0003215)2.44173977
55Recurrent abscess formation (HP:0002722)2.42809893
56Sudden death (HP:0001699)2.41789315
57Purpura (HP:0000979)2.38257729
58Optic disc pallor (HP:0000543)2.37965355
59Amniotic constriction ring (HP:0009775)2.35652853
60Abnormality of placental membranes (HP:0011409)2.35652853
61Glycosuria (HP:0003076)2.35629003
62Abnormality of urine glucose concentration (HP:0011016)2.35629003
63Lipoatrophy (HP:0100578)2.35103705
64Abnormality of aromatic amino acid family metabolism (HP:0004338)2.32486465
65Congenital, generalized hypertrichosis (HP:0004540)2.23096494
66Trismus (HP:0000211)2.22879641
67Hyperphosphaturia (HP:0003109)2.13537458
68Muscle hypertrophy of the lower extremities (HP:0008968)2.12593906
69Abnormality of macrophages (HP:0004311)2.11942349
70Methylmalonic aciduria (HP:0012120)2.09842995
71Pancytopenia (HP:0001876)2.07694381
72CNS demyelination (HP:0007305)2.05921229
73Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.03816098
74Calf muscle hypertrophy (HP:0008981)2.02448472
75Abnormal pupillary function (HP:0007686)1.99314292
76Thrombocytosis (HP:0001894)1.97811404
77Vertebral compression fractures (HP:0002953)1.97394990
78Abnormal urine phosphate concentration (HP:0012599)1.93615281
79Increased serum ferritin (HP:0003281)1.93088335
80Paralysis (HP:0003470)1.93076042
81Nausea (HP:0002018)1.92268831
82Hepatosplenomegaly (HP:0001433)1.92076383
83Abnormal respiratory motile cilium physiology (HP:0012261)1.90601075
84Poor head control (HP:0002421)1.90571991
85Breast hypoplasia (HP:0003187)1.90084800
86Testicular atrophy (HP:0000029)1.87794664
87Axonal loss (HP:0003447)1.85491182
88Recurrent bacterial skin infections (HP:0005406)1.85369457
89Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.84962014
90Abnormal protein N-linked glycosylation (HP:0012347)1.84962014
91Abnormal protein glycosylation (HP:0012346)1.84962014
92Abnormal glycosylation (HP:0012345)1.84962014
93Systemic lupus erythematosus (HP:0002725)1.84309099
94Protrusio acetabuli (HP:0003179)1.83843138
95Renal tubular dysfunction (HP:0000124)1.81350728
96IgM deficiency (HP:0002850)1.80176875
97Eczematoid dermatitis (HP:0000976)1.79806584
98Rhabdomyolysis (HP:0003201)1.78332826
99Vomiting (HP:0002013)1.78313387
100Dilated cardiomyopathy (HP:0001644)1.78295530
101Rough bone trabeculation (HP:0100670)1.78260689
102Rhinitis (HP:0012384)1.78147195
103Increased IgM level (HP:0003496)1.78033446
104Abnormality of the umbilical cord (HP:0010881)1.77633385
105Sparse eyelashes (HP:0000653)1.75094132
106Abnormal ciliary motility (HP:0012262)1.75093573
107Abnormality of dentin (HP:0010299)1.74602005
108Microvesicular hepatic steatosis (HP:0001414)1.74451056
109Carpal bone hypoplasia (HP:0001498)1.74231110
110Esophageal neoplasm (HP:0100751)1.71344869
111Neoplasm of head and neck (HP:0012288)1.71344869
112Methylmalonic acidemia (HP:0002912)1.70866930
113Abnormality of the anterior horn cell (HP:0006802)1.68705329
114Degeneration of anterior horn cells (HP:0002398)1.68705329
115Stomatitis (HP:0010280)1.68553894
116Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.68507663
117Chronic sinusitis (HP:0011109)1.68282117
118Reduced antithrombin III activity (HP:0001976)1.68218273
119Cerebral hypomyelination (HP:0006808)1.67517287
120Secondary amenorrhea (HP:0000869)1.67429285
121Abnormality of iron homeostasis (HP:0011031)1.67362442
122Type 1 muscle fiber predominance (HP:0003803)1.66819726
123Abnormalities of placenta or umbilical cord (HP:0001194)1.66638710
124Palpitations (HP:0001962)1.65041224
125Blindness (HP:0000618)1.64525155
126Pulmonary artery stenosis (HP:0004415)1.63992372
127Conjunctival hamartoma (HP:0100780)1.63830672
128Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.62943440
129Lethargy (HP:0001254)1.62829674
130Abnormal respiratory motile cilium morphology (HP:0005938)1.62655306
131Abnormal respiratory epithelium morphology (HP:0012253)1.62655306
132Stenosis of the external auditory canal (HP:0000402)1.62529312
133Abnormality of the calf musculature (HP:0001430)1.60784808
134Neutropenia (HP:0001875)1.60302213
135Abnormal trabecular bone morphology (HP:0100671)1.60044317
136Nemaline bodies (HP:0003798)1.60004041
137Progressive neurologic deterioration (HP:0002344)1.59236215
138Neck muscle weakness (HP:0000467)1.57928871
139Soft skin (HP:0000977)1.57484004
140Muscle fiber inclusion bodies (HP:0100299)1.57276775
141X-linked dominant inheritance (HP:0001423)1.57055605
142Abnormality of the heme biosynthetic pathway (HP:0010472)1.56946426
143Emotional lability (HP:0000712)1.56700342
144Elevated erythrocyte sedimentation rate (HP:0003565)1.56459094
145Chronic obstructive pulmonary disease (HP:0006510)1.55695407
146Obstructive lung disease (HP:0006536)1.55695407
147Ileus (HP:0002595)1.55636646

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.19375244
2NME25.54885116
3PBK3.11884236
4BUB13.06618252
5PIM22.84055069
6MYLK2.75866358
7TESK22.71179179
8MAP3K122.50169400
9TLK12.48762897
10MST42.40130291
11LIMK12.24561932
12NME12.16932657
13STK392.08481239
14KDR1.99945889
15EIF2AK11.95382175
16STK161.91641224
17TESK11.86343228
18IRAK31.81784428
19BLK1.80552245
20ILK1.77480043
21TTN1.71053685
22OBSCN1.70510852
23LRRK21.66521511
24ARAF1.65043121
25BCKDK1.64983968
26ABL21.60664047
27TXK1.54421885
28WEE11.48397933
29WNK41.48019601
30ADRBK21.31608202
31DAPK31.30631878
32IRAK41.28346359
33EIF2AK31.22507807
34VRK11.13914649
35TAOK21.12941716
36TBK11.12813781
37GRK61.12774988
38DYRK21.08670237
39PLK41.08160044
40EPHB11.06832712
41PAK41.02411769
42RIPK40.99658819
43GRK10.98704750
44MUSK0.98427692
45MAP2K20.95957275
46MAP3K30.95594503
47EPHB20.94531514
48PAK10.91339858
49CDK80.89465231
50SRPK10.89305326
51MAPK150.87626795
52BRAF0.83423188
53MAP3K110.82241393
54TAF10.81067803
55IKBKB0.81020237
56PIK3CG0.80585158
57DAPK10.80296172
58STK240.79521048
59SYK0.77395353
60STK40.77230067
61TYK20.76112506
62RPS6KA50.75255317
63FGR0.75246407
64MAP4K10.73723160
65CSF1R0.73025211
66CDC70.71527328
67AURKB0.70744896
68MATK0.69090835
69ROCK20.68795131
70KIT0.68270018
71GRK70.67638082
72MAP2K60.67309944
73ERN10.67165763
74IRAK10.66976745
75GRK50.66907691
76RPS6KB20.66294379
77ITK0.66200901
78BTK0.65491817
79TAOK30.65387715
80IKBKE0.64703081
81RPS6KA40.64682117
82STK38L0.64595502
83FES0.64292077
84TNK20.61571956
85AURKA0.60021185
86PKN10.59976977
87TIE10.59362556
88MAPKAPK50.57977727
89TRIB30.57030299
90PIK3CA0.56495073
91MOS0.56278385
92MAP3K80.54943237
93TRPM70.54244460
94NEK90.54099673
95SCYL20.50555959
96CSNK2A10.50372495
97CAMK2D0.50307290
98MET0.49794188
99DYRK30.49474310
100ZAK0.47930915
101OXSR10.47633515
102BMX0.47139312
103TTK0.46331088
104ZAP700.46023576
105IRAK20.45884317
106LMTK20.45729344
107ROCK10.45715180
108LATS20.45085398
109PRKD10.44170633
110CSNK1G30.44079154
111LYN0.43955562
112PIM10.42929455
113ADRBK10.42756655
114PRKG20.42578737
115PRKCD0.42230274
116MAPKAPK30.42205250
117PLK10.41950607
118PAK20.41239520
119PRKCQ0.41102507
120BCR0.40475489
121PRKCI0.40418585
122CCNB10.39756866
123MAP2K30.39402977
124DDR20.39331311
125JAK30.37314398
126CSNK2A20.37178939
127TEC0.36022534
128PDK20.35798762
129CSK0.35224023
130NUAK10.34284257
131LCK0.33412620
132INSRR0.33010286
133MAPKAPK20.32693147
134BMPR1B0.30001378
135CHEK20.26734129
136PLK30.25701711
137BMPR20.25024488
138PRKCA0.24824060

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.99430612
2Oxidative phosphorylation_Homo sapiens_hsa001905.14185652
3Parkinsons disease_Homo sapiens_hsa050124.43636060
4Proteasome_Homo sapiens_hsa030504.12180814
5Alzheimers disease_Homo sapiens_hsa050103.29058368
6Huntingtons disease_Homo sapiens_hsa050163.22897265
7Protein export_Homo sapiens_hsa030603.19595129
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.18116435
9RNA polymerase_Homo sapiens_hsa030203.13812859
10Cardiac muscle contraction_Homo sapiens_hsa042602.27128392
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.68580092
12Pyrimidine metabolism_Homo sapiens_hsa002401.64201542
13Primary immunodeficiency_Homo sapiens_hsa053401.58751264
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.49537948
15Spliceosome_Homo sapiens_hsa030401.47599121
16DNA replication_Homo sapiens_hsa030301.27337745
17Homologous recombination_Homo sapiens_hsa034401.26468112
18Fatty acid elongation_Homo sapiens_hsa000621.23956145
19Glutathione metabolism_Homo sapiens_hsa004801.14307515
20Nucleotide excision repair_Homo sapiens_hsa034201.09508075
21Other glycan degradation_Homo sapiens_hsa005111.04955538
22Steroid biosynthesis_Homo sapiens_hsa001001.04529707
23Type I diabetes mellitus_Homo sapiens_hsa049401.02697554
24Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.00860028
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99662396
26Arachidonic acid metabolism_Homo sapiens_hsa005900.96380641
27Mismatch repair_Homo sapiens_hsa034300.93621835
28Basal transcription factors_Homo sapiens_hsa030220.89247147
29Chemical carcinogenesis_Homo sapiens_hsa052040.87260637
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85552398
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.84254941
32Rheumatoid arthritis_Homo sapiens_hsa053230.83744435
33Folate biosynthesis_Homo sapiens_hsa007900.83175613
34Systemic lupus erythematosus_Homo sapiens_hsa053220.82202512
35Graft-versus-host disease_Homo sapiens_hsa053320.81835786
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.81692263
37Lysosome_Homo sapiens_hsa041420.80100149
38Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78430468
39Malaria_Homo sapiens_hsa051440.77930527
40RNA transport_Homo sapiens_hsa030130.75730144
41Peroxisome_Homo sapiens_hsa041460.75431527
42Linoleic acid metabolism_Homo sapiens_hsa005910.74592173
43One carbon pool by folate_Homo sapiens_hsa006700.73993977
44Staphylococcus aureus infection_Homo sapiens_hsa051500.73184129
45Purine metabolism_Homo sapiens_hsa002300.72285632
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71531512
47Phagosome_Homo sapiens_hsa041450.70188816
48Vitamin digestion and absorption_Homo sapiens_hsa049770.69805295
49Epstein-Barr virus infection_Homo sapiens_hsa051690.69433294
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68462718
51Base excision repair_Homo sapiens_hsa034100.67504563
52Drug metabolism - other enzymes_Homo sapiens_hsa009830.67446214
53Metabolic pathways_Homo sapiens_hsa011000.66967491
54Arginine and proline metabolism_Homo sapiens_hsa003300.65917757
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.64694657
56Sphingolipid metabolism_Homo sapiens_hsa006000.63596013
57SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62772527
58Sulfur relay system_Homo sapiens_hsa041220.62678842
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62658013
60Ether lipid metabolism_Homo sapiens_hsa005650.62427116
61Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60151541
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60111334
63Pentose phosphate pathway_Homo sapiens_hsa000300.59903924
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.59520018
65Vibrio cholerae infection_Homo sapiens_hsa051100.59009355
66Viral myocarditis_Homo sapiens_hsa054160.58909478
67Sulfur metabolism_Homo sapiens_hsa009200.57907230
68Asthma_Homo sapiens_hsa053100.57806080
69Allograft rejection_Homo sapiens_hsa053300.56066585
70alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55774744
71Fructose and mannose metabolism_Homo sapiens_hsa000510.55751553
72Leishmaniasis_Homo sapiens_hsa051400.55221424
73RNA degradation_Homo sapiens_hsa030180.54622742
74Legionellosis_Homo sapiens_hsa051340.54474305
75Pertussis_Homo sapiens_hsa051330.54099739
76Mineral absorption_Homo sapiens_hsa049780.53834147
77Collecting duct acid secretion_Homo sapiens_hsa049660.53373202
78N-Glycan biosynthesis_Homo sapiens_hsa005100.52872816
79Carbon metabolism_Homo sapiens_hsa012000.52674261
80Autoimmune thyroid disease_Homo sapiens_hsa053200.51025471
81p53 signaling pathway_Homo sapiens_hsa041150.50295366
82Galactose metabolism_Homo sapiens_hsa000520.48947420
83Tryptophan metabolism_Homo sapiens_hsa003800.48475080
84Primary bile acid biosynthesis_Homo sapiens_hsa001200.47929805
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.46366635
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.44423621
87Antigen processing and presentation_Homo sapiens_hsa046120.43493642
88Propanoate metabolism_Homo sapiens_hsa006400.42990112
89ECM-receptor interaction_Homo sapiens_hsa045120.42301439
90Nitrogen metabolism_Homo sapiens_hsa009100.41745686
91Caffeine metabolism_Homo sapiens_hsa002320.40695971
92Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.38381693
93Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.37892751
94Hematopoietic cell lineage_Homo sapiens_hsa046400.37652610
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36973726
96Pyruvate metabolism_Homo sapiens_hsa006200.36816310
97Retinol metabolism_Homo sapiens_hsa008300.36391017
98Steroid hormone biosynthesis_Homo sapiens_hsa001400.36245995
99Shigellosis_Homo sapiens_hsa051310.36178668
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35556357
101Cell cycle_Homo sapiens_hsa041100.34571134
102Apoptosis_Homo sapiens_hsa042100.34271368
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34061612
104Dilated cardiomyopathy_Homo sapiens_hsa054140.33977376
105Fanconi anemia pathway_Homo sapiens_hsa034600.33789038
106Salmonella infection_Homo sapiens_hsa051320.33435799
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33404659
108Glycosaminoglycan degradation_Homo sapiens_hsa005310.33065793
109Vitamin B6 metabolism_Homo sapiens_hsa007500.31363409
110Renin-angiotensin system_Homo sapiens_hsa046140.31016838
111NF-kappa B signaling pathway_Homo sapiens_hsa040640.30986309
112Cysteine and methionine metabolism_Homo sapiens_hsa002700.29826573
113Tyrosine metabolism_Homo sapiens_hsa003500.29256653
114Leukocyte transendothelial migration_Homo sapiens_hsa046700.29195315
115Fatty acid degradation_Homo sapiens_hsa000710.27852255
116Histidine metabolism_Homo sapiens_hsa003400.25825059
117Fat digestion and absorption_Homo sapiens_hsa049750.25338272
118Tuberculosis_Homo sapiens_hsa051520.25104057
119Regulation of autophagy_Homo sapiens_hsa041400.24535389
1202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.22883175
121Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.20875375
122Phenylalanine metabolism_Homo sapiens_hsa003600.20354345
123NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20156423
124Protein digestion and absorption_Homo sapiens_hsa049740.19428029
125HIF-1 signaling pathway_Homo sapiens_hsa040660.19409818
126Herpes simplex infection_Homo sapiens_hsa051680.18637246
127Tight junction_Homo sapiens_hsa045300.16688799
128Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.16384354
129Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.15294906
130Amoebiasis_Homo sapiens_hsa051460.15067544

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