SERPINA6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.49273176
2L-phenylalanine catabolic process (GO:0006559)7.49273176
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.19171976
4L-phenylalanine metabolic process (GO:0006558)7.19171976
5triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.99396607
6aromatic amino acid family catabolic process (GO:0009074)6.47057000
7high-density lipoprotein particle remodeling (GO:0034375)6.15921814
8epoxygenase P450 pathway (GO:0019373)6.15845761
9negative regulation of fibrinolysis (GO:0051918)6.05323073
10glyoxylate metabolic process (GO:0046487)5.82067005
11regulation of fibrinolysis (GO:0051917)5.74417823
12kynurenine metabolic process (GO:0070189)5.62130092
13indole-containing compound catabolic process (GO:0042436)5.55548178
14indolalkylamine catabolic process (GO:0046218)5.55548178
15tryptophan catabolic process (GO:0006569)5.55548178
16reverse cholesterol transport (GO:0043691)5.54563939
17alpha-linolenic acid metabolic process (GO:0036109)5.51855779
18peptidyl-glutamic acid carboxylation (GO:0017187)5.49546367
19protein carboxylation (GO:0018214)5.49546367
20bile acid biosynthetic process (GO:0006699)5.47516186
21urea cycle (GO:0000050)5.41426928
22urea metabolic process (GO:0019627)5.41426928
23sulfur amino acid catabolic process (GO:0000098)5.36583760
24tryptophan metabolic process (GO:0006568)5.30744857
25cysteine metabolic process (GO:0006534)5.29085291
26regulation of cholesterol esterification (GO:0010872)5.27808901
27omega-hydroxylase P450 pathway (GO:0097267)5.25046117
28plasma lipoprotein particle remodeling (GO:0034369)5.21261299
29protein-lipid complex remodeling (GO:0034368)5.21261299
30macromolecular complex remodeling (GO:0034367)5.21261299
31exogenous drug catabolic process (GO:0042738)5.14553778
32phospholipid efflux (GO:0033700)5.04645291
33serine family amino acid catabolic process (GO:0009071)5.01118479
34negative regulation of cholesterol transport (GO:0032375)4.99310339
35negative regulation of sterol transport (GO:0032372)4.99310339
36plasma lipoprotein particle clearance (GO:0034381)4.95244892
37nitrogen cycle metabolic process (GO:0071941)4.94543062
38regulation of protein activation cascade (GO:2000257)4.91062300
39bile acid metabolic process (GO:0008206)4.88541332
40regulation of triglyceride catabolic process (GO:0010896)4.80838277
41triglyceride homeostasis (GO:0070328)4.73528347
42acylglycerol homeostasis (GO:0055090)4.73528347
43aromatic amino acid family metabolic process (GO:0009072)4.70205498
44tyrosine metabolic process (GO:0006570)4.68060992
45complement activation, alternative pathway (GO:0006957)4.66330204
46lysine catabolic process (GO:0006554)4.66185575
47lysine metabolic process (GO:0006553)4.66185575
48negative regulation of protein activation cascade (GO:2000258)4.64350426
49cellular ketone body metabolic process (GO:0046950)4.61047997
50cholesterol efflux (GO:0033344)4.60567931
51amino-acid betaine metabolic process (GO:0006577)4.57584601
52homocysteine metabolic process (GO:0050667)4.57493239
53glycine metabolic process (GO:0006544)4.56079792
54alpha-amino acid catabolic process (GO:1901606)4.55863308
55negative regulation of hemostasis (GO:1900047)4.53947045
56negative regulation of blood coagulation (GO:0030195)4.53947045
57plasma lipoprotein particle assembly (GO:0034377)4.52859592
58phenylpropanoid metabolic process (GO:0009698)4.51173210
59regulation of complement activation (GO:0030449)4.49888783
60fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.48693142
61protein activation cascade (GO:0072376)4.44285485
62proline metabolic process (GO:0006560)4.43784335
63serine family amino acid biosynthetic process (GO:0009070)4.33179594
64glutamate metabolic process (GO:0006536)4.31390095
65acute-phase response (GO:0006953)4.26992542
66serine family amino acid metabolic process (GO:0009069)4.26492745
67imidazole-containing compound metabolic process (GO:0052803)4.26474897
68low-density lipoprotein particle remodeling (GO:0034374)4.25548096
69cellular amino acid catabolic process (GO:0009063)4.22062480
70drug catabolic process (GO:0042737)4.21656975
71negative regulation of coagulation (GO:0050819)4.14413829
72bile acid and bile salt transport (GO:0015721)4.13743013
73regulation of humoral immune response (GO:0002920)4.11880368
74fibrinolysis (GO:0042730)4.10697920
75cellular modified amino acid catabolic process (GO:0042219)4.09859074
76cellular glucuronidation (GO:0052695)4.08914248
77protein-lipid complex assembly (GO:0065005)4.07522848
78positive regulation of hemostasis (GO:1900048)4.06516243
79positive regulation of blood coagulation (GO:0030194)4.06516243
80negative regulation of complement activation (GO:0045916)4.06503738
81negative regulation of wound healing (GO:0061045)4.04628971
82cholesterol homeostasis (GO:0042632)4.03068163
83ethanol metabolic process (GO:0006067)4.02896250
84dicarboxylic acid biosynthetic process (GO:0043650)4.01907147
85complement activation, classical pathway (GO:0006958)4.01038121
86plasma lipoprotein particle organization (GO:0071827)4.00586244
87aldehyde catabolic process (GO:0046185)3.98518266
88ketone body metabolic process (GO:1902224)3.97870632
89sterol homeostasis (GO:0055092)3.96923594
90positive regulation of lipid catabolic process (GO:0050996)3.95819445
91indolalkylamine metabolic process (GO:0006586)3.95480963
92arginine metabolic process (GO:0006525)3.95416415
93negative regulation of lipase activity (GO:0060192)3.93983511
94positive regulation of lipoprotein lipase activity (GO:0051006)3.93641176
95positive regulation of triglyceride lipase activity (GO:0061365)3.93641176
96coenzyme catabolic process (GO:0009109)3.92307579
97blood coagulation, intrinsic pathway (GO:0007597)3.92168797
98benzene-containing compound metabolic process (GO:0042537)3.91896348
99oxidative demethylation (GO:0070989)3.88497465
100ethanol oxidation (GO:0006069)3.87878609
101complement activation (GO:0006956)3.87834820
102phospholipid homeostasis (GO:0055091)3.86521643
103regulation of apoptotic cell clearance (GO:2000425)3.85872168
104very-low-density lipoprotein particle assembly (GO:0034379)3.83905876
105intestinal cholesterol absorption (GO:0030299)3.82186795
106short-chain fatty acid metabolic process (GO:0046459)3.81479602
107cellular biogenic amine catabolic process (GO:0042402)3.81234979
108amine catabolic process (GO:0009310)3.81234979
109positive regulation of fatty acid biosynthetic process (GO:0045723)3.78695439
110positive regulation of coagulation (GO:0050820)3.78337747
111protein-lipid complex subunit organization (GO:0071825)3.77634157
112lipoprotein metabolic process (GO:0042157)3.77346248
113regulation of cholesterol homeostasis (GO:2000188)3.71125925
114cofactor catabolic process (GO:0051187)3.70442246
115regulation of bile acid biosynthetic process (GO:0070857)3.69646284
116organic acid catabolic process (GO:0016054)3.68537436
117carboxylic acid catabolic process (GO:0046395)3.68537436
118aspartate family amino acid catabolic process (GO:0009068)3.65418677
119uronic acid metabolic process (GO:0006063)3.63995709
120glucuronate metabolic process (GO:0019585)3.63995709
121regulation of plasminogen activation (GO:0010755)3.60735827
122flavonoid metabolic process (GO:0009812)3.59057375
123drug metabolic process (GO:0017144)3.56557212
124regulation of lipoprotein particle clearance (GO:0010984)3.55694538
125acute inflammatory response (GO:0002526)3.51851607
126cytolysis (GO:0019835)3.42297095
127regulation of cholesterol biosynthetic process (GO:0045540)3.18348811
128sterol transport (GO:0015918)3.18339001
129cholesterol transport (GO:0030301)3.18339001

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.38398661
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.25531468
3* LXR_22158963_ChIP-Seq_LIVER_Mouse6.56281248
4EGR1_23403033_ChIP-Seq_LIVER_Mouse6.50309077
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.13573221
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.05012323
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.96987815
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.92869483
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.80255348
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.21990211
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.05623010
12* ESR1_17901129_ChIP-ChIP_LIVER_Mouse12.0857247
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99650281
14CLOCK_20551151_ChIP-Seq_293T_Human1.96030797
15GATA1_22025678_ChIP-Seq_K562_Human1.84758795
16* FOXA2_19822575_ChIP-Seq_HepG2_Human1.66368677
17HTT_18923047_ChIP-ChIP_STHdh_Human1.52250428
18TRIM28_21343339_ChIP-Seq_HEK293_Human1.51533145
19* HNF4A_19822575_ChIP-Seq_HepG2_Human1.43885019
20TP63_17297297_ChIP-ChIP_HaCaT_Human1.42823318
21PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.36547650
22THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29911000
23ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29448849
24SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28992022
25RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20546331
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17923446
27ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17777482
28GATA3_24758297_ChIP-Seq_MCF-7_Human1.17717332
29SOX2_27498859_Chip-Seq_STOMACH_Mouse1.17430554
30ZNF263_19887448_ChIP-Seq_K562_Human1.15691834
31PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14371381
32RXRA_24833708_ChIP-Seq_LIVER_Mouse1.13073564
33ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11208106
34TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03598860
35ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02747196
36STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01893927
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.01368396
38TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.01250722
39GATA4_25053715_ChIP-Seq_YYC3_Human0.95958332
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95942422
41FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95688593
42PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90269069
43SOX2_20726797_ChIP-Seq_SW620_Human0.88474805
44BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.86630665
45AUTS2_25519132_ChIP-Seq_293T-REX_Human0.85847831
46LXR_22292898_ChIP-Seq_THP-1_Human0.85504047
47GATA1_19941826_ChIP-Seq_K562_Human0.84175025
48SMC4_20622854_ChIP-Seq_HELA_Human0.83971257
49HIF1A_21447827_ChIP-Seq_MCF-7_Human0.83649951
50RUNX1_27514584_Chip-Seq_MCF-7_Human0.83112340
51NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.82030939
52NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.81813244
53SALL4_18804426_ChIP-ChIP_XEN_Mouse0.81367332
54RARA_24833708_ChIP-Seq_LIVER_Mouse0.81153598
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.80490957
56SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.79763291
57PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.79658142
58ZNF217_24962896_ChIP-Seq_MCF-7_Human0.78155608
59SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77484706
60CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.76873198
61ESR2_21235772_ChIP-Seq_MCF-7_Human0.76532115
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.76457463
63POU5F1_16518401_ChIP-PET_MESCs_Mouse0.76103876
64DNAJC2_21179169_ChIP-ChIP_NT2_Human0.73785061
65BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.72318841
66IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.71564514
67AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.69386449
68TET1_21451524_ChIP-Seq_MESCs_Mouse0.68506941
69TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.67821664
70KDM5A_27292631_Chip-Seq_BREAST_Human0.67712797
71* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.67509667
72RARB_24833708_ChIP-Seq_LIVER_Mouse0.66680525
73GATA6_25053715_ChIP-Seq_YYC3_Human0.65013780
74GATA1_19941827_ChIP-Seq_MEL_Mouse0.62287218
75ERG_21242973_ChIP-ChIP_JURKAT_Human0.61486509
76CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.61065308
77CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.60959350
78ELF5_23300383_ChIP-Seq_T47D_Human0.59922022
79RAC3_21632823_ChIP-Seq_H3396_Human0.59581229
80CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.59177823
81TCF4_18268006_ChIP-ChIP_LS174T_Human0.59083835
82E2F1_20622854_ChIP-Seq_HELA_Human0.58821605
83SOX11_22085726_ChIP-Seq_ESNs_Mouse0.58686821
84KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.57780783
85P68_20966046_ChIP-Seq_HELA_Human0.57345027
86SPI1_26923725_Chip-Seq_HPCs_Mouse0.57159661
87FOXA1_25552417_ChIP-Seq_VCAP_Human0.57028460
88SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.56987656
89* CEBPB_22108803_ChIP-Seq_LS180_Human0.56573788
90EOMES_21245162_ChIP-Seq_HESCs_Human0.56285096
91SOX17_20123909_ChIP-Seq_XEN_Mouse0.56193985
92FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.56177058
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.55271071
94P63_26484246_Chip-Seq_KERATINOCYTES_Human0.55114842
95KAP1_22055183_ChIP-Seq_ESCs_Mouse0.54524651
96MYC_19915707_ChIP-ChIP_AK7_Human0.54443906
97PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.54423380
98RAD21_21589869_ChIP-Seq_MESCs_Mouse0.53777782
99DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.53655034
100ATF3_27146783_Chip-Seq_COLON_Human0.53306624
101RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.52988757
102ESR1_21235772_ChIP-Seq_MCF-7_Human0.52675896
103GATA2_19941826_ChIP-Seq_K562_Human0.52585798
104PPAR_26484153_Chip-Seq_NCI-H1993_Human0.52093526
105EGR1_19032775_ChIP-ChIP_M12_Human0.51662225
106RACK7_27058665_Chip-Seq_MCF-7_Human0.50328393
107STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.49079610
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.49057138
109CBP_21632823_ChIP-Seq_H3396_Human0.48732781
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.46725325
111ESET_19884257_ChIP-Seq_ESCs_Mouse0.46361419
112SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.45513828
113TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.45102166
114TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.44485534
115Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.44482892
116ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.44186546
117CREB1_26743006_Chip-Seq_LNCaP_Human0.43407515
118P53_21459846_ChIP-Seq_SAOS-2_Human0.43353438
119CDX2_20551321_ChIP-Seq_CACO-2_Human0.42452107
120AR_20517297_ChIP-Seq_VCAP_Human0.41983664
121GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.41964817
122NRF2_20460467_ChIP-Seq_MEFs_Mouse0.41957882
123NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.41957882
124FOXO3_23340844_ChIP-Seq_DLD1_Human0.41286427
125CTCF_27219007_Chip-Seq_Bcells_Human0.40979726
126PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.40945283
127ESR1_20079471_ChIP-ChIP_T-47D_Human0.40919296
128AR_21909140_ChIP-Seq_LNCAP_Human0.40472003
129* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.40050413
130GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.39465260
131SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.39014388
132BCOR_27268052_Chip-Seq_Bcells_Human0.38862667
133EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.38224765
134* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.38196390
135TAF2_19829295_ChIP-Seq_ESCs_Human0.38157063
136NFIB_24661679_ChIP-Seq_LUNG_Mouse0.38119687
137MYC_27129775_Chip-Seq_CORNEA_Mouse0.37560883
138PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.37529171

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.15892941
2MP0005360_urolithiasis7.11507537
3MP0005085_abnormal_gallbladder_physiolo6.37106377
4MP0005365_abnormal_bile_salt6.16695494
5MP0008875_abnormal_xenobiotic_pharmacok4.97213153
6MP0005083_abnormal_biliary_tract4.37829855
7MP0003806_abnormal_nucleotide_metabolis4.05806345
8MP0010329_abnormal_lipoprotein_level3.77132053
9MP0003252_abnormal_bile_duct3.71806760
10MP0009840_abnormal_foam_cell3.31514610
11MP0001666_abnormal_nutrient_absorption3.13346086
12MP0005332_abnormal_amino_acid2.66241639
13MP0003195_calcinosis2.56423835
14MP0003868_abnormal_feces_composition2.40794030
15MP0001346_abnormal_lacrimal_gland2.31941531
16MP0003191_abnormal_cellular_cholesterol2.20899515
17MP0005379_endocrine/exocrine_gland_phen2.13608126
18MP0000609_abnormal_liver_physiology2.12267011
19MP0002118_abnormal_lipid_homeostasis2.09843788
20MP0004019_abnormal_vitamin_homeostasis1.97294902
21MP0002138_abnormal_hepatobiliary_system1.78282538
22MP0005319_abnormal_enzyme/_coenzyme1.73393875
23MP0003705_abnormal_hypodermis_morpholog1.56320159
24MP0003656_abnormal_erythrocyte_physiolo1.52803398
25MP0005058_abnormal_lysosome_morphology1.51193749
26MP0005451_abnormal_body_composition1.49467357
27MP0009697_abnormal_copulation1.48410616
28MP0001764_abnormal_homeostasis1.47376501
29MP0005584_abnormal_enzyme/coenzyme_acti1.46515518
30MP0005084_abnormal_gallbladder_morpholo1.45040581
31MP0002132_abnormal_respiratory_system1.32744631
32MP0001919_abnormal_reproductive_system1.30909211
33MP0000566_synostosis1.26984878
34MP0005220_abnormal_exocrine_pancreas1.26579270
35MP0003011_delayed_dark_adaptation1.26521569
36MP0009643_abnormal_urine_homeostasis1.25567577
37MP0000598_abnormal_liver_morphology1.21352082
38MP0002089_abnormal_postnatal_growth/wei1.15901113
39MP0003186_abnormal_redox_activity1.13451794
40MP0001881_abnormal_mammary_gland1.10586083
41MP0009780_abnormal_chondrocyte_physiolo1.10278036
42MP0000604_amyloidosis1.09799172
43MP0010368_abnormal_lymphatic_system1.04649331
44MP0003183_abnormal_peptide_metabolism1.03965014
45MP0004233_abnormal_muscle_weight1.03673343
46MP0003172_abnormal_lysosome_physiology0.99926440
47MP0005408_hypopigmentation0.97441312
48MP0002282_abnormal_trachea_morphology0.97437317
49MP0009763_increased_sensitivity_to0.95253044
50MP0002254_reproductive_system_inflammat0.94491151
51MP0005636_abnormal_mineral_homeostasis0.87445588
52MP0005647_abnormal_sex_gland0.85419098
53MP0009764_decreased_sensitivity_to0.84535681
54* MP0009642_abnormal_blood_homeostasis0.84059899
55MP0002078_abnormal_glucose_homeostasis0.80786472
56MP0002909_abnormal_adrenal_gland0.80297237
57MP0005389_reproductive_system_phenotype0.78860534
58MP0009765_abnormal_xenobiotic_induced0.76745742
59MP0009053_abnormal_anal_canal0.74915557
60MP0002098_abnormal_vibrissa_morphology0.74607840
61MP0009672_abnormal_birth_weight0.74386460
62* MP0008469_abnormal_protein_level0.74327488
63MP0006036_abnormal_mitochondrial_physio0.73694662
64MP0005376_homeostasis/metabolism_phenot0.71706391
65MP0003329_amyloid_beta_deposits0.70020188
66MP0000627_abnormal_mammary_gland0.69631168
67MP0000427_abnormal_hair_cycle0.69043196
68MP0005334_abnormal_fat_pad0.68944247
69MP0003941_abnormal_skin_development0.66501286
70MP0004130_abnormal_muscle_cell0.66417158
71MP0000639_abnormal_adrenal_gland0.65858451
72MP0009384_cardiac_valve_regurgitation0.65805857
73MP0003879_abnormal_hair_cell0.65429666
74MP0002168_other_aberrant_phenotype0.61954906
75MP0003122_maternal_imprinting0.61480654
76MP0002971_abnormal_brown_adipose0.61242182
77MP0002876_abnormal_thyroid_physiology0.60097966
78MP0001756_abnormal_urination0.60083547
79MP0005448_abnormal_energy_balance0.59497896
80MP0003690_abnormal_glial_cell0.58997442
81MP0004264_abnormal_extraembryonic_tissu0.57373646
82MP0005535_abnormal_body_temperature0.56805799
83MP0002928_abnormal_bile_duct0.55757529
84MP0005266_abnormal_metabolism0.55041455
85MP0000681_abnormal_thyroid_gland0.54042486
86MP0001661_extended_life_span0.53269658
87MP0001765_abnormal_ion_homeostasis0.52171236
88MP0002090_abnormal_vision0.51128015
89MP0005464_abnormal_platelet_physiology0.49275528
90MP0010234_abnormal_vibrissa_follicle0.49167014
91MP0003638_abnormal_response/metabolism_0.48803305
92MP0001944_abnormal_pancreas_morphology0.47316826
93MP0005409_darkened_coat_color0.44643037
94MP0005670_abnormal_white_adipose0.44054232
95MP0005164_abnormal_response_to0.43864727
96MP0008872_abnormal_physiological_respon0.42797157
97MP0002136_abnormal_kidney_physiology0.42456630
98MP0002896_abnormal_bone_mineralization0.41339851
99MP0005646_abnormal_pituitary_gland0.41335928
100MP0008873_increased_physiological_sensi0.38674146
101MP0005395_other_phenotype0.37334570
102MP0008874_decreased_physiological_sensi0.37198940
103MP0003718_maternal_effect0.37037798
104* MP0003953_abnormal_hormone_level0.37005935
105MP0006035_abnormal_mitochondrial_morpho0.36434086
106MP0004782_abnormal_surfactant_physiolog0.36353008
107MP0009115_abnormal_fat_cell0.36350345
108MP0005248_abnormal_Harderian_gland0.36331284
109MP0003123_paternal_imprinting0.35841077
110MP0001243_abnormal_dermal_layer0.35650573
111MP0005501_abnormal_skin_physiology0.35457276
112MP0004883_abnormal_blood_vessel0.35394726
113MP0008438_abnormal_cutaneous_collagen0.35243729
114MP0003959_abnormal_lean_body0.34811582
115MP0002837_dystrophic_cardiac_calcinosis0.34498369
116MP0002796_impaired_skin_barrier0.33987208
117MP0005187_abnormal_penis_morphology0.33629361
118MP0003936_abnormal_reproductive_system0.33541855
119MP0005666_abnormal_adipose_tissue0.32914872
120MP0003075_altered_response_to0.32326859
121MP0003315_abnormal_perineum_morphology0.32249302
122MP0005167_abnormal_blood-brain_barrier0.31958140
123MP0003943_abnormal_hepatobiliary_system0.31585773
124MP0003283_abnormal_digestive_organ0.30847666
125MP0000249_abnormal_blood_vessel0.28679102
126MP0002060_abnormal_skin_morphology0.26318620
127MP0002822_catalepsy0.26231355
128MP0002970_abnormal_white_adipose0.26138360
129MP0004147_increased_porphyrin_level0.24562261
130MP0001915_intracranial_hemorrhage0.24553213
131MP0002135_abnormal_kidney_morphology0.24241848
132MP0005023_abnormal_wound_healing0.22839033
133MP0005166_decreased_susceptibility_to0.22699147

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.92982246
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.35644811
3Intrahepatic cholestasis (HP:0001406)6.75649327
4Prolonged partial thromboplastin time (HP:0003645)6.47415321
5Hypobetalipoproteinemia (HP:0003563)6.39134356
6Abnormality of monocarboxylic acid metabolism (HP:0010996)6.36127242
7Xanthomatosis (HP:0000991)6.24222282
8Hyperlipoproteinemia (HP:0010980)5.42220854
9Joint hemorrhage (HP:0005261)4.95064346
10Hypolipoproteinemia (HP:0010981)4.85852157
11Abnormality of the common coagulation pathway (HP:0010990)4.59513329
12Hyperammonemia (HP:0001987)4.56216611
13Complement deficiency (HP:0004431)4.47977861
14Ketosis (HP:0001946)4.46058498
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.40089104
16Hyperglycinemia (HP:0002154)4.26169122
17Hypoalphalipoproteinemia (HP:0003233)4.25422378
18Hypoglycemic coma (HP:0001325)4.17001073
19Epidermoid cyst (HP:0200040)4.10431922
20Fat malabsorption (HP:0002630)4.09161091
21Abnormality of sulfur amino acid metabolism (HP:0004339)4.07622603
22Abnormality of glutamine family amino acid metabolism (HP:0010902)4.05722117
23Abnormality of serine family amino acid metabolism (HP:0010894)4.01429438
24Abnormality of glycine metabolism (HP:0010895)4.01429438
25Abnormality of methionine metabolism (HP:0010901)4.01037203
26Hyperglycinuria (HP:0003108)3.98991408
27Abnormality of the intrinsic pathway (HP:0010989)3.90766349
28Abnormality of aspartate family amino acid metabolism (HP:0010899)3.86258978
29Hypercholesterolemia (HP:0003124)3.74342922
30Abnormality of pyrimidine metabolism (HP:0004353)3.60991755
31Hyperbilirubinemia (HP:0002904)3.52404689
32Conjugated hyperbilirubinemia (HP:0002908)3.37096552
33Ketoacidosis (HP:0001993)3.37034166
34Abnormality of complement system (HP:0005339)3.29225161
35Abnormality of fatty-acid metabolism (HP:0004359)3.23873852
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.19150516
37Hypochromic microcytic anemia (HP:0004840)3.18247690
38Steatorrhea (HP:0002570)3.16090671
39Hepatocellular carcinoma (HP:0001402)3.15689639
40Delayed CNS myelination (HP:0002188)2.99053554
41Abnormality of nucleobase metabolism (HP:0010932)2.88682077
42Abnormal tarsal ossification (HP:0008369)2.87529495
43Spontaneous abortion (HP:0005268)2.87407383
44Acanthocytosis (HP:0001927)2.87270154
45Abnormality of serum amino acid levels (HP:0003112)2.87156326
46Myocardial infarction (HP:0001658)2.81886902
47Oligomenorrhea (HP:0000876)2.73878474
48Reduced antithrombin III activity (HP:0001976)2.69743158
49Metabolic acidosis (HP:0001942)2.69549776
50Hypoglycemic seizures (HP:0002173)2.67363332
51Osteomalacia (HP:0002749)2.59644547
52Dicarboxylic aciduria (HP:0003215)2.59484964
53Abnormality of dicarboxylic acid metabolism (HP:0010995)2.59484964
54Abnormal gallbladder morphology (HP:0012437)2.56395933
55Skin nodule (HP:0200036)2.56198029
56Abnormality of carpal bone ossification (HP:0006257)2.55641561
57Spastic diplegia (HP:0001264)2.55110288
58Purpura (HP:0000979)2.54138287
59Cholelithiasis (HP:0001081)2.52659661
60Abnormality of purine metabolism (HP:0004352)2.52527238
61Poikilocytosis (HP:0004447)2.52089438
62Late onset (HP:0003584)2.51167536
63Flat acetabular roof (HP:0003180)2.50609691
64Gout (HP:0001997)2.47482733
65Glomerulonephritis (HP:0000099)2.45003010
66Vascular calcification (HP:0004934)2.44429813
67Esophageal varix (HP:0002040)2.40883190
68Lethargy (HP:0001254)2.40164724
69Neonatal onset (HP:0003623)2.38623441
70Enlarged kidneys (HP:0000105)2.38590451
71Mitral stenosis (HP:0001718)2.36487261
72Mucopolysacchariduria (HP:0008155)2.33663266
73Urinary glycosaminoglycan excretion (HP:0003541)2.33663266
74Amyloidosis (HP:0011034)2.33217215
75Pancreatitis (HP:0001733)2.31790330
76Abnormal gallbladder physiology (HP:0012438)2.31092969
77Cholecystitis (HP:0001082)2.31092969
78Arthropathy (HP:0003040)2.28633929
79Cerebral edema (HP:0002181)2.24050188
80Thrombophlebitis (HP:0004418)2.21908792
81Menorrhagia (HP:0000132)2.21606356
82Hyperinsulinemic hypoglycemia (HP:0000825)2.20232297
83Concave nail (HP:0001598)2.19730261
84Systemic lupus erythematosus (HP:0002725)2.19575074
85Abnormality of the pancreatic islet cells (HP:0006476)2.19453137
86Abnormality of endocrine pancreas physiology (HP:0012093)2.19453137
87Cardiovascular calcification (HP:0011915)2.19350494
88Irritability (HP:0000737)2.17356552
89Abnormality of the Achilles tendon (HP:0005109)2.16120213
90Malnutrition (HP:0004395)2.13898408
91Reticulocytosis (HP:0001923)2.13702617
92Hemorrhage of the eye (HP:0011885)2.13465227
93Hyperphosphaturia (HP:0003109)2.11531061
94Gingival bleeding (HP:0000225)2.11002118
95Abnormality of polysaccharide metabolism (HP:0011012)2.09656101
96Abnormality of glycosaminoglycan metabolism (HP:0004371)2.09656101
97Abnormality of mucopolysaccharide metabolism (HP:0011020)2.09656101
98Abnormal cartilage morphology (HP:0002763)2.03531061
99Brushfield spots (HP:0001088)2.03019238
100Vomiting (HP:0002013)2.02556231
101Generalized aminoaciduria (HP:0002909)2.02470322
102Abnormality of the gallbladder (HP:0005264)2.01003461
103Widely patent fontanelles and sutures (HP:0004492)2.00263290
104Increased serum pyruvate (HP:0003542)1.97878789
105Abnormality of proline metabolism (HP:0010907)1.96101343
106Hydroxyprolinuria (HP:0003080)1.96101343
107Hypophosphatemia (HP:0002148)1.95373701
108Sparse lateral eyebrow (HP:0005338)1.92159113
109Abnormal hand bone ossification (HP:0010660)1.91101924
110Abnormal urine phosphate concentration (HP:0012599)1.90939712
111Abnormality of iron homeostasis (HP:0011031)1.88569111
112Abnormality of transition element cation homeostasis (HP:0011030)1.88476188
113Hyperglycemia (HP:0003074)1.87735670
114Opisthotonus (HP:0002179)1.86984352
115Rickets (HP:0002748)1.86966682
116Sensorimotor neuropathy (HP:0007141)1.84919955
117Pancreatic islet-cell hyperplasia (HP:0004510)1.83008782
118Elevated alkaline phosphatase (HP:0003155)1.81220596
119Hypophosphatemic rickets (HP:0004912)1.80920754
120Abnormal ossification of hand bones (HP:0005921)1.78809218
121Recurrent gram-negative bacterial infections (HP:0005420)1.78313653
122Abnormal foot bone ossification (HP:0010675)1.78016842
123Bifid scrotum (HP:0000048)1.75423085
124Nephritis (HP:0000123)1.75136913
125Pulmonary embolism (HP:0002204)1.72904345
126Alkalosis (HP:0001948)1.72564922
127Abnormality of alkaline phosphatase activity (HP:0004379)1.71276041
128Abnormal enzyme/coenzyme activity (HP:0012379)1.71203121
129Gangrene (HP:0100758)1.67970233
130Abnormality of glycolysis (HP:0004366)1.67956886
131Potter facies (HP:0002009)1.65312409
132Facial shape deformation (HP:0011334)1.65312409
133Right ventricular cardiomyopathy (HP:0011663)1.56733342
134Retinal atrophy (HP:0001105)1.52554522

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.93740085
2PKN24.66303712
3SIK14.54381618
4FGFR44.31935641
5ERN13.82852091
6TRIB33.78112067
7EIF2AK13.59637645
8CDK122.98090275
9TAOK32.71453395
10INSRR2.51270962
11FLT32.50252640
12SCYL22.38923670
13MAPKAPK32.21011936
14TSSK62.20733957
15PTK62.18577897
16MAP3K102.14451285
17TESK12.11588794
18LATS12.09512356
19MST1R1.97192663
20EPHA21.81750955
21MAP2K41.71954285
22ERBB41.65178932
23DAPK21.61846087
24MAPK111.55983949
25PIK3CA1.51448274
26PIK3CG1.44789186
27MUSK1.42988929
28CDK71.39693929
29KDR1.35845255
30TYK21.31469229
31ABL21.30108155
32RIPK11.30070730
33NEK91.23440955
34MET1.22399618
35WNK41.18000189
36GRK61.13316811
37FGFR21.08497198
38MAP3K111.08285012
39MAP2K31.06154913
40JAK21.05919287
41LIMK11.03397710
42PTK21.01434607
43ERBB21.00617974
44CDK61.00413788
45MAP3K70.98118762
46LMTK20.93130281
47CDK40.92977780
48ZAP700.91922139
49DYRK1B0.89201097
50TESK20.86249830
51MAP3K30.85189718
52PDGFRA0.83239187
53SMG10.82718645
54EPHB10.81259426
55PRKAA20.80730999
56PRKCZ0.80443537
57FRK0.78039996
58RET0.77118188
59TGFBR20.76744175
60TBK10.76415933
61EPHA30.74676405
62TYRO30.73529665
63TIE10.73008756
64EIF2AK30.71767653
65RPS6KB20.69075800
66MAPK120.66604313
67MTOR0.66555244
68CSK0.65930729
69GSK3A0.65669180
70MAPK40.65337786
71PRKACG0.65299910
72LRRK20.60247626
73TAOK20.59233064
74RPS6KB10.58813854
75JAK10.58095237
76CDC42BPA0.55037646
77NEK20.53301925
78ICK0.52786145
79CSNK2A20.52286217
80CSF1R0.52270334
81BRSK10.52024989
82CAMK1D0.51472144
83MAP2K10.51020388
84PRKCI0.50574319
85LATS20.49633064
86STK38L0.48535875
87MAP2K20.48399310
88ALK0.48053359
89CSNK1G10.46663295
90STK380.46406508
91CSNK1D0.46125149
92MAPK150.45788428
93CAMKK10.45467664
94EEF2K0.45335799
95SGK10.44071398
96NEK10.43479248
97FGFR10.42134140
98PDPK10.42070940
99PRKG20.41996076
100PAK20.41113549
101CSNK2A10.40885505
102WEE10.40814502
103EPHA40.39628857
104SGK4940.38451676
105SGK2230.38451676
106PRKAA10.38101311
107IGF1R0.37963314
108WNK10.36871862
109SRC0.36404873
110EIF2AK20.36219401
111STK30.36196200
112MAP3K10.35465710
113FER0.34964093
114TAOK10.34165665
115PRKG10.32844734
116PBK0.31701585
117PRKCG0.31534010
118PINK10.31519552
119MAP2K60.30431226
120CAMK1G0.29881160
121PDK10.29737104
122MAPK30.29560473
123GRK10.29449739
124MAP3K80.28517547
125CAMK2G0.28108801
126MAP3K120.27824992
127KSR20.27610064
128CSNK1E0.27444374
129DMPK0.27013110
130MAP3K140.26433666
131SGK30.26372417
132MAP3K50.26294248
133MAP3K20.26170195
134PRKCQ0.26010936
135MAPK70.25687598
136FGFR30.24665978
137PRKACB0.24371204
138CSNK1G20.23627603
139NTRK10.22767585
140EPHB20.22159873
141CSNK1G30.22080190
142EGFR0.21470053
143BMX0.21120480
144PAK40.20704765

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.08662809
2Nitrogen metabolism_Homo sapiens_hsa009103.68016957
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.59661248
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.22706771
5Arginine biosynthesis_Homo sapiens_hsa002202.98479951
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.78470700
7Tryptophan metabolism_Homo sapiens_hsa003802.66255586
8Complement and coagulation cascades_Homo sapiens_hsa046102.65185143
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.64908340
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.62138429
11Fatty acid degradation_Homo sapiens_hsa000712.54460880
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.45594730
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.31286080
14Butanoate metabolism_Homo sapiens_hsa006502.20742018
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.15154927
16Chemical carcinogenesis_Homo sapiens_hsa052041.96106020
17Propanoate metabolism_Homo sapiens_hsa006401.95997292
18Histidine metabolism_Homo sapiens_hsa003401.93766860
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.93723618
20Peroxisome_Homo sapiens_hsa041461.88460480
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.84833421
22Fatty acid metabolism_Homo sapiens_hsa012121.79860386
23Fat digestion and absorption_Homo sapiens_hsa049751.78893006
24PPAR signaling pathway_Homo sapiens_hsa033201.77657072
25beta-Alanine metabolism_Homo sapiens_hsa004101.73734218
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.73047870
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.71585533
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.71297013
29Staphylococcus aureus infection_Homo sapiens_hsa051501.67192530
30Caffeine metabolism_Homo sapiens_hsa002321.66857719
31Retinol metabolism_Homo sapiens_hsa008301.61984070
32Selenocompound metabolism_Homo sapiens_hsa004501.58869051
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.57799438
34Maturity onset diabetes of the young_Homo sapiens_hsa049501.55402190
35Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.49966000
36Bile secretion_Homo sapiens_hsa049761.46420391
37Phenylalanine metabolism_Homo sapiens_hsa003601.43848344
38Pyruvate metabolism_Homo sapiens_hsa006201.41816599
39Sulfur metabolism_Homo sapiens_hsa009201.36847154
40Steroid biosynthesis_Homo sapiens_hsa001001.35820059
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35393064
42Fatty acid elongation_Homo sapiens_hsa000621.34169723
43Tyrosine metabolism_Homo sapiens_hsa003501.29974534
44Starch and sucrose metabolism_Homo sapiens_hsa005001.26931524
45Biosynthesis of amino acids_Homo sapiens_hsa012301.25997375
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.25977589
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.17229890
48Carbon metabolism_Homo sapiens_hsa012001.15702156
49Folate biosynthesis_Homo sapiens_hsa007901.13159598
50ABC transporters_Homo sapiens_hsa020101.11147300
51Cyanoamino acid metabolism_Homo sapiens_hsa004601.08242626
52Arginine and proline metabolism_Homo sapiens_hsa003301.07340777
53Glycerolipid metabolism_Homo sapiens_hsa005610.97680180
54Other glycan degradation_Homo sapiens_hsa005110.96769496
55Lysine degradation_Homo sapiens_hsa003100.93893438
56Sulfur relay system_Homo sapiens_hsa041220.93523246
57Vitamin B6 metabolism_Homo sapiens_hsa007500.90483589
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.88799329
59One carbon pool by folate_Homo sapiens_hsa006700.88280912
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.78802692
61Vitamin digestion and absorption_Homo sapiens_hsa049770.74644040
62Arachidonic acid metabolism_Homo sapiens_hsa005900.73267715
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72592595
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.71739748
65Glutathione metabolism_Homo sapiens_hsa004800.66280045
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.58133438
67Pentose phosphate pathway_Homo sapiens_hsa000300.54355486
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48438754
69Fatty acid biosynthesis_Homo sapiens_hsa000610.42505698
70Metabolic pathways_Homo sapiens_hsa011000.42488637
71Sphingolipid metabolism_Homo sapiens_hsa006000.39728238
72Galactose metabolism_Homo sapiens_hsa000520.26549641
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.25356570
74Insulin resistance_Homo sapiens_hsa049310.24173348
75Linoleic acid metabolism_Homo sapiens_hsa005910.23400097
76Protein digestion and absorption_Homo sapiens_hsa049740.22944426
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22400499
78Pancreatic secretion_Homo sapiens_hsa049720.21681124
79Pertussis_Homo sapiens_hsa051330.20166874
80Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19716862
81Prion diseases_Homo sapiens_hsa050200.17449620
82Mineral absorption_Homo sapiens_hsa049780.16653218
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.15222960
84Fructose and mannose metabolism_Homo sapiens_hsa000510.15016219
85Glucagon signaling pathway_Homo sapiens_hsa049220.08979727
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.05529192
87AMPK signaling pathway_Homo sapiens_hsa041520.00934581
88Type II diabetes mellitus_Homo sapiens_hsa04930-0.2470566
89N-Glycan biosynthesis_Homo sapiens_hsa00510-0.2461834
90Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2367836
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.2347864
92Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.2231208
93Renin-angiotensin system_Homo sapiens_hsa04614-0.2158907
94Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2097505
95Hepatitis C_Homo sapiens_hsa05160-0.2053434
96Bladder cancer_Homo sapiens_hsa05219-0.1908308
97Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1851581
98African trypanosomiasis_Homo sapiens_hsa05143-0.1834923
99Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1426502
100Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1221822
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1122260
102Amoebiasis_Homo sapiens_hsa05146-0.1115057
103Insulin signaling pathway_Homo sapiens_hsa04910-0.0866665
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0822237
105Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0493006
106Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0381929
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0358027
108Lysosome_Homo sapiens_hsa04142-0.0144508
109Prolactin signaling pathway_Homo sapiens_hsa04917-0.0001267

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