SERPINB5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratinization (GO:0031424)9.48977844
2hemidesmosome assembly (GO:0031581)9.25496813
3keratinocyte proliferation (GO:0043616)7.75717360
4hair cycle (GO:0042633)7.71977030
5molting cycle (GO:0042303)7.71977030
6keratinocyte differentiation (GO:0030216)7.38942921
7multicellular organismal water homeostasis (GO:0050891)6.92181329
8bundle of His cell to Purkinje myocyte communication (GO:0086069)6.62992216
9sphingoid metabolic process (GO:0046519)6.25549870
10epidermal cell differentiation (GO:0009913)5.94280859
11gap junction assembly (GO:0016264)5.82270635
12water homeostasis (GO:0030104)5.80602015
13intermediate filament organization (GO:0045109)5.76249702
14peptide cross-linking (GO:0018149)5.62730327
15epidermis development (GO:0008544)5.62568488
16keratinocyte development (GO:0003334)5.55109695
17regulation of hair follicle development (GO:0051797)5.52945457
18sphingosine metabolic process (GO:0006670)5.48589015
19surfactant homeostasis (GO:0043129)5.45270661
20regulation of phospholipase A2 activity (GO:0032429)5.39870431
21interferon-gamma secretion (GO:0072643)5.29650493
22cell adhesion mediated by integrin (GO:0033627)5.12673275
23positive regulation of hair cycle (GO:0042635)4.99829292
24positive regulation of hair follicle development (GO:0051798)4.99829292
25viral transcription (GO:0019083)4.97744978
26diol metabolic process (GO:0034311)4.95530540
27polarized epithelial cell differentiation (GO:0030859)4.84665559
28translational termination (GO:0006415)4.67033789
29glucosamine-containing compound catabolic process (GO:1901072)4.60417157
30regulation of chemokine secretion (GO:0090196)4.54329830
31regulation of ruffle assembly (GO:1900027)4.52886574
32dichotomous subdivision of an epithelial terminal unit (GO:0060600)4.45584409
33ectoderm development (GO:0007398)4.43667955
34skin morphogenesis (GO:0043589)4.40619452
35regulation of cell proliferation involved in kidney development (GO:1901722)4.38332967
36ribosomal small subunit biogenesis (GO:0042274)4.35901814
37epithelial cell differentiation involved in prostate gland development (GO:0060742)4.35313568
38hypotonic response (GO:0006971)4.30487887
39long-chain fatty acid biosynthetic process (GO:0042759)4.21009760
40regulation of hair cycle (GO:0042634)4.17836656
41positive regulation of interleukin-8 secretion (GO:2000484)4.15782878
42regulation of epidermis development (GO:0045682)4.13224545
43negative regulation of keratinocyte proliferation (GO:0010839)4.11895025
44regulation of keratinocyte differentiation (GO:0045616)4.07556828
45negative regulation of cell fate specification (GO:0009996)4.07060007
46mesodermal cell differentiation (GO:0048333)4.06261172
47regulation of transforming growth factor beta2 production (GO:0032909)4.04217613
48fatty acid elongation (GO:0030497)4.00271251
49positive regulation of keratinocyte differentiation (GO:0045618)3.95502728
50atrioventricular valve morphogenesis (GO:0003181)3.87037548
51negative regulation of epidermis development (GO:0045683)3.80482757
52endodermal cell differentiation (GO:0035987)3.80064728
53viral life cycle (GO:0019058)3.77668280
54detection of bacterium (GO:0016045)3.77312761
55negative regulation of chondrocyte differentiation (GO:0032331)3.77057521
56cardiac right ventricle morphogenesis (GO:0003215)3.68739764
57positive regulation of chemokine secretion (GO:0090197)3.68535031
58SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.67042460
59ventricular cardiac muscle cell action potential (GO:0086005)3.66287160
60translational elongation (GO:0006414)3.64871367
61protein targeting to ER (GO:0045047)3.62443675
62cotranslational protein targeting to membrane (GO:0006613)3.58684184
63cell junction assembly (GO:0034329)3.57191933
64negative regulation of cell fate commitment (GO:0010454)3.54101697
65establishment of protein localization to endoplasmic reticulum (GO:0072599)3.52983302
66cellular protein complex disassembly (GO:0043624)3.50966095
67intermediate filament cytoskeleton organization (GO:0045104)3.47121965
68regulation of hypersensitivity (GO:0002883)3.42030824
69cell junction organization (GO:0034330)3.41836410
70regulation of interleukin-8 secretion (GO:2000482)3.39578887
71protein localization to endosome (GO:0036010)3.39534569
72intermediate filament-based process (GO:0045103)3.38147896
73regulation of transforming growth factor beta1 production (GO:0032908)3.37986569
74protein localization to endoplasmic reticulum (GO:0070972)3.35102647
75skin development (GO:0043588)3.34077788
76planar cell polarity pathway involved in neural tube closure (GO:0090179)3.33205925
77regulation of epidermal cell differentiation (GO:0045604)3.31696238
78nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.30051679
79phosphatidylinositol acyl-chain remodeling (GO:0036149)3.28267670
80regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.24687198
81eyelid development in camera-type eye (GO:0061029)3.20879974
82detection of other organism (GO:0098543)3.18262469
83maturation of SSU-rRNA (GO:0030490)3.17906027
84regulation of cardioblast differentiation (GO:0051890)3.17636266
85cyclooxygenase pathway (GO:0019371)3.12384935
86positive regulation of vesicle fusion (GO:0031340)3.12098348
87negative regulation of stress fiber assembly (GO:0051497)3.11126678
88negative regulation of interferon-gamma production (GO:0032689)3.08568725
89heart valve morphogenesis (GO:0003179)3.06829109
90limb bud formation (GO:0060174)3.06563782
91negative regulation of kidney development (GO:0090185)3.02620609
92phosphatidylserine acyl-chain remodeling (GO:0036150)3.02184640
93negative regulation of interleukin-2 production (GO:0032703)3.00727232
94regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.00133818
95ribosomal small subunit assembly (GO:0000028)2.99034301
96regulation of heart rate by cardiac conduction (GO:0086091)2.98267921
97prostaglandin biosynthetic process (GO:0001516)2.96653309
98prostanoid biosynthetic process (GO:0046457)2.96653309
99long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.93329088
100linoleic acid metabolic process (GO:0043651)2.93263912
101establishment of planar polarity (GO:0001736)2.92319331
102establishment of tissue polarity (GO:0007164)2.92319331
103cell-substrate junction assembly (GO:0007044)2.91876453
104regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.91759495
105positive regulation of epidermis development (GO:0045684)2.89605388
106mammary gland epithelial cell proliferation (GO:0033598)2.89554125
107morphogenesis of embryonic epithelium (GO:0016331)2.89477956
108renal filtration (GO:0097205)2.87669621
109protein complex disassembly (GO:0043241)2.87585340
110primary alcohol catabolic process (GO:0034310)2.86387056
111cellular response to interferon-alpha (GO:0035457)2.86362995
112epithelium development (GO:0060429)2.84728789
113cell communication involved in cardiac conduction (GO:0086065)2.84000296
114cellular copper ion homeostasis (GO:0006878)2.83088681
115establishment of epithelial cell polarity (GO:0090162)2.81846356
116negative regulation of T cell mediated immunity (GO:0002710)2.81404162
117cytoskeletal anchoring at plasma membrane (GO:0007016)2.80564009
118G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.79031505
119renal system development (GO:0072001)2.76231483
120translational initiation (GO:0006413)2.76017214
121positive regulation of glomerulus development (GO:0090193)2.75906430
122epithelial cell-cell adhesion (GO:0090136)2.75236043
123positive regulation of interleukin-4 production (GO:0032753)2.74755329
124hair follicle morphogenesis (GO:0031069)2.71945083
125regulation of transforming growth factor beta production (GO:0071634)2.71875283
126regulation of keratinocyte proliferation (GO:0010837)2.71594471
127regulation of metalloenzyme activity (GO:0048552)2.70993423
128focal adhesion assembly (GO:0048041)2.70598139
129cell-substrate adherens junction assembly (GO:0007045)2.70598139
130negative regulation of acute inflammatory response (GO:0002674)2.69288473
131intestinal epithelial cell development (GO:0060576)2.67914149
132cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.67203354
133epithelial cell proliferation (GO:0050673)2.66720907
134positive regulation of epidermal cell differentiation (GO:0045606)2.65816914
135phospholipid scrambling (GO:0017121)2.63378347
136chemical homeostasis within a tissue (GO:0048875)2.63115043
137protein targeting to membrane (GO:0006612)2.61540735
138lateral sprouting from an epithelium (GO:0060601)2.60894480
139membrane raft organization (GO:0031579)2.60633118
140macromolecular complex disassembly (GO:0032984)2.60228908
141hair cycle process (GO:0022405)2.59154124
142molting cycle process (GO:0022404)2.59154124
143L-serine transport (GO:0015825)2.57527170
144wound healing (GO:0042060)2.55628711
145mammary gland development (GO:0030879)2.52437985
146negative regulation of stem cell proliferation (GO:2000647)2.50255208
147positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.50213188
148negative regulation of cartilage development (GO:0061037)2.50205083
149adherens junction organization (GO:0034332)2.49342057
150cell-cell junction assembly (GO:0007043)2.46956140
151natural killer cell mediated immunity (GO:0002228)2.42814097
152natural killer cell mediated cytotoxicity (GO:0042267)2.42814097
153neural crest cell development (GO:0014032)2.42009215
154cardiac muscle cell action potential involved in contraction (GO:0086002)2.40674674
155positive regulation of protein export from nucleus (GO:0046827)2.40291136
156regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.39784289
157negative regulation of epidermal cell differentiation (GO:0045605)2.39222370
158desmosome organization (GO:0002934)15.8361367
159establishment of skin barrier (GO:0061436)10.7410403
160regulation of water loss via skin (GO:0033561)10.0719335

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse6.32309881
2* SOX9_24532713_ChIP-Seq_HFSC_Mouse3.11472655
3P63_26484246_Chip-Seq_KERATINOCYTES_Human3.00332577
4SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.83776655
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.55235491
6ZNF263_19887448_ChIP-Seq_K562_Human2.41867445
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.32042360
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.30651480
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.18831476
10* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.10459595
11* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.10459595
12ESR2_21235772_ChIP-Seq_MCF-7_Human2.07987030
13* TP63_17297297_ChIP-ChIP_HaCaT_Human14.5979328
14FOXO3_23340844_ChIP-Seq_DLD1_Human1.93602682
15ZNF217_24962896_ChIP-Seq_MCF-7_Human1.79756680
16TCF4_18268006_ChIP-ChIP_LS174T_Human1.69749312
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.66748924
18AR_21909140_ChIP-Seq_LNCAP_Human1.59772154
19AR_21572438_ChIP-Seq_LNCaP_Human1.58087354
20* SOX2_20726797_ChIP-Seq_SW620_Human1.55871158
21TP63_23658742_ChIP-Seq_EP156T_Human1.52703299
22CJUN_26792858_Chip-Seq_BT549_Human1.49311118
23SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.46943188
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.36683620
25KLF5_25053715_ChIP-Seq_YYC3_Human1.36352603
26CLOCK_20551151_ChIP-Seq_293T_Human1.36068514
27RUNX1_27514584_Chip-Seq_MCF-7_Human1.35717991
28BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.35444768
29TP53_18474530_ChIP-ChIP_U2OS_Human1.35423902
30RXR_22108803_ChIP-Seq_LS180_Human1.28294027
31ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.26803331
32CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.23161120
33TP63_22573176_ChIP-Seq_HFKS_Human1.21956256
34RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21725708
35CDX2_20551321_ChIP-Seq_CACO-2_Human1.21473153
36NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.17662491
37KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16894460
38RARG_19884340_ChIP-ChIP_MEFs_Mouse1.16672638
39TP53_20018659_ChIP-ChIP_R1E_Mouse1.15741327
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.15042968
41P300_27058665_Chip-Seq_ZR-75-30cells_Human1.14912098
42AHR_22903824_ChIP-Seq_MCF-7_Human1.12458037
43GATA4_25053715_ChIP-Seq_YYC3_Human1.12368204
44PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11269363
45* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.08371401
46* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.07854397
47ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.04910092
48EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.04504254
49RACK7_27058665_Chip-Seq_MCF-7_Human1.04130379
50ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03511772
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02435034
52GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02298700
53UBF1/2_26484160_Chip-Seq_HMECs_Human1.02117497
54GATA3_24758297_ChIP-Seq_MCF-7_Human1.00919705
55SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99800795
56TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.98833141
57BCAT_22108803_ChIP-Seq_LS180_Human0.98549388
58ATF3_27146783_Chip-Seq_COLON_Human0.97078537
59GATA6_25053715_ChIP-Seq_YYC3_Human0.96562394
60EZH2_27304074_Chip-Seq_ESCs_Mouse0.95695675
61GATA1_22025678_ChIP-Seq_K562_Human0.95417742
62TP53_16413492_ChIP-PET_HCT116_Human0.94713847
63FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.94442785
64EED_16625203_ChIP-ChIP_MESCs_Mouse0.94116732
65CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93368506
66SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91213480
67FOXM1_26456572_ChIP-Seq_MCF-7_Human0.90560756
68CEBPB_22108803_ChIP-Seq_LS180_Human0.90551359
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.90133631
70ELK3_25401928_ChIP-Seq_HUVEC_Human0.88918229
71HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87811269
72* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87507569
73GATA6_21074721_ChIP-Seq_CACO-2_Human0.84413474
74UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.84063423
75ESR1_20079471_ChIP-ChIP_T-47D_Human0.83595234
76PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.83413119
77BMI1_23680149_ChIP-Seq_NPCS_Mouse0.82880831
78ARNT_22903824_ChIP-Seq_MCF-7_Human0.81738991
79JARID2_20075857_ChIP-Seq_MESCs_Mouse0.81722692
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.81602132
81SOX2_27498859_Chip-Seq_STOMACH_Mouse0.81274418
82SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.80310086
83RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.80017816
84BRD4_25478319_ChIP-Seq_HGPS_Human0.79803591
85TCF4_22108803_ChIP-Seq_LS180_Human0.79785656
86EZH2_27294783_Chip-Seq_ESCs_Mouse0.78406950
87SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.77575700
88JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.77336953
89FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.75692992
90VDR_22108803_ChIP-Seq_LS180_Human0.75125158
91SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.74758699
92RNF2_27304074_Chip-Seq_ESCs_Mouse0.74629251
93ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.72863030
94GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.72795539
95NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.72581860
96RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.72371968
97SMAD3_21741376_ChIP-Seq_HESCs_Human0.72248836
98TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.72067027
99TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.71772888
100JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.71601159
101TBX20_22080862_ChIP-Seq_HEART_Mouse0.71537766
102TBX20_22328084_ChIP-Seq_HEART_Mouse0.71537766
103BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.71052338
104CTCF_27219007_Chip-Seq_Bcells_Human0.70774821
105SA1_27219007_Chip-Seq_ERYTHROID_Human0.70482938
106NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.70211174
107ERG_21242973_ChIP-ChIP_JURKAT_Human0.69405529
108CBX2_27304074_Chip-Seq_ESCs_Mouse0.69113254
109TP53_22127205_ChIP-Seq_IMR90_Human0.69025948
110P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.68756894
111CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.68692836
112JARID2_20064375_ChIP-Seq_MESCs_Mouse0.67532313
113CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.67248135
114SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.66882412
115PIAS1_25552417_ChIP-Seq_VCAP_Human0.66330040
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.65685379
117EGR1_19032775_ChIP-ChIP_M12_Human0.65579464
118NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.65218406
119EZH2_18974828_ChIP-Seq_MESCs_Mouse0.64980907
120RNF2_18974828_ChIP-Seq_MESCs_Mouse0.64980907
121FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.64841850
122FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.63776798
123CDX2_19796622_ChIP-Seq_MESCs_Mouse0.62694620
124ELK1_22589737_ChIP-Seq_MCF10A_Human0.62611422
125CHD1_26751641_Chip-Seq_LNCaP_Human0.62260820
126STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.61636272
127* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.61553087
128ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.61465790
129GATA2_21666600_ChIP-Seq_HMVEC_Human0.60880797
130LXR_22292898_ChIP-Seq_THP-1_Human0.60548020
131EP300_21415370_ChIP-Seq_HL-1_Mouse0.58876755
132AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.58475000
133PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.58401066
134ELK4_26923725_Chip-Seq_MESODERM_Mouse0.58031321
135NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.56243321
136NRF2_20460467_ChIP-Seq_MEFs_Mouse0.56243321
137NANOG_18692474_ChIP-Seq_MEFs_Mouse0.55242498
138WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.52127370
139TET1_21490601_ChIP-Seq_MESCs_Mouse0.51970373
140NANOG_18555785_ChIP-Seq_MESCs_Mouse0.51823709

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.44505618
2MP0010234_abnormal_vibrissa_follicle5.80359261
3MP0005275_abnormal_skin_tensile5.27767456
4MP0005501_abnormal_skin_physiology4.57581168
5MP0003941_abnormal_skin_development4.54016887
6MP0004381_abnormal_hair_follicle4.40364008
7MP0000579_abnormal_nail_morphology3.77670146
8MP0000383_abnormal_hair_follicle3.75366345
9MP0010678_abnormal_skin_adnexa3.61872826
10MP0002254_reproductive_system_inflammat3.51315230
11MP0001216_abnormal_epidermal_layer3.50181574
12MP0002060_abnormal_skin_morphology3.48876697
13MP0002098_abnormal_vibrissa_morphology3.34843372
14MP0003453_abnormal_keratinocyte_physiol3.14754349
15MP0010771_integument_phenotype3.01560815
16MP0000647_abnormal_sebaceous_gland2.86854170
17MP0000467_abnormal_esophagus_morphology2.63477583
18MP0000377_abnormal_hair_follicle2.60551685
19MP0000566_synostosis2.52056266
20MP0004947_skin_inflammation2.34759413
21MP0002009_preneoplasia2.33245265
22MP0000427_abnormal_hair_cycle2.27662580
23MP0000762_abnormal_tongue_morphology2.04199282
24MP0001346_abnormal_lacrimal_gland1.92955624
25MP0009379_abnormal_foot_pigmentation1.86082752
26MP0003705_abnormal_hypodermis_morpholog1.71581053
27MP0009931_abnormal_skin_appearance1.68231825
28MP0005451_abnormal_body_composition1.64394513
29MP0001191_abnormal_skin_condition1.60365388
30MP0004185_abnormal_adipocyte_glucose1.45836386
31MP0000367_abnormal_coat/_hair1.40681823
32MP0001243_abnormal_dermal_layer1.39202500
33MP0003136_yellow_coat_color1.37982904
34MP0000678_abnormal_parathyroid_gland1.37814307
35MP0005360_urolithiasis1.31115686
36MP0001851_eye_inflammation1.26309040
37MP0008260_abnormal_autophagy1.21247474
38MP0001340_abnormal_eyelid_morphology1.16832470
39MP0002234_abnormal_pharynx_morphology1.14741094
40* MP0003566_abnormal_cell_adhesion1.13508230
41MP0009780_abnormal_chondrocyte_physiolo1.08121132
42MP0010352_gastrointestinal_tract_polyps1.07534545
43MP0000537_abnormal_urethra_morphology0.93343393
44MP0005023_abnormal_wound_healing0.91115816
45MP0005257_abnormal_intraocular_pressure0.91083926
46MP0000465_gastrointestinal_hemorrhage0.90975450
47MP0001849_ear_inflammation0.89724871
48MP0002006_tumorigenesis0.89255113
49MP0005409_darkened_coat_color0.85888503
50MP0002166_altered_tumor_susceptibility0.85025024
51MP0003011_delayed_dark_adaptation0.84682070
52MP0010030_abnormal_orbit_morphology0.84302129
53MP0000627_abnormal_mammary_gland0.84094269
54MP0004885_abnormal_endolymph0.82570437
55MP0009053_abnormal_anal_canal0.78649529
56MP0000538_abnormal_urinary_bladder0.76969054
57MP0008004_abnormal_stomach_pH0.75168189
58MP0002282_abnormal_trachea_morphology0.75149961
59MP0003315_abnormal_perineum_morphology0.73974426
60MP0000858_altered_metastatic_potential0.72387152
61MP0002249_abnormal_larynx_morphology0.69081821
62MP0009384_cardiac_valve_regurgitation0.68723443
63MP0005076_abnormal_cell_differentiation0.67634439
64MP0004272_abnormal_basement_membrane0.63384535
65MP0004019_abnormal_vitamin_homeostasis0.61850329
66MP0004782_abnormal_surfactant_physiolog0.61320321
67MP0002177_abnormal_outer_ear0.60639116
68MP0003755_abnormal_palate_morphology0.60577820
69MP0005197_abnormal_uvea_morphology0.59940831
70MP0002877_abnormal_melanocyte_morpholog0.58628966
71MP0003191_abnormal_cellular_cholesterol0.57288163
72MP0004264_abnormal_extraembryonic_tissu0.57286044
73MP0001299_abnormal_eye_distance/0.56699902
74MP0005394_taste/olfaction_phenotype0.54203500
75MP0005499_abnormal_olfactory_system0.54203500
76MP0005193_abnormal_anterior_eye0.53992519
77MP0003045_fibrosis0.53080261
78MP0001784_abnormal_fluid_regulation0.52193225
79MP0003436_decreased_susceptibility_to0.51620423
80MP0002233_abnormal_nose_morphology0.51560607
81MP0000462_abnormal_digestive_system0.51335108
82MP0000516_abnormal_urinary_system0.50769309
83MP0005367_renal/urinary_system_phenotyp0.50769309
84MP0002277_abnormal_respiratory_mucosa0.50596799
85MP0002095_abnormal_skin_pigmentation0.48673934
86MP0002697_abnormal_eye_size0.47760344
87MP0010368_abnormal_lymphatic_system0.47469068
88MP0003091_abnormal_cell_migration0.47345968
89MP0005508_abnormal_skeleton_morphology0.45552414
90MP0006138_congestive_heart_failure0.44449725
91MP0005075_abnormal_melanosome_morpholog0.43888949
92MP0000613_abnormal_salivary_gland0.43584147
93MP0002111_abnormal_tail_morphology0.43186521
94MP0000470_abnormal_stomach_morphology0.42802421
95MP0002089_abnormal_postnatal_growth/wei0.42151656
96MP0003763_abnormal_thymus_physiology0.41519691
97MP0002148_abnormal_hypersensitivity_rea0.41355254
98MP0003329_amyloid_beta_deposits0.41002944
99MP0009250_abnormal_appendicular_skeleto0.40987623
100MP0005248_abnormal_Harderian_gland0.40901854
101MP0003828_pulmonary_edema0.40145353
102MP0008789_abnormal_olfactory_epithelium0.40086397
103MP0005164_abnormal_response_to0.38883442
104MP0005666_abnormal_adipose_tissue0.37589508
105MP0004197_abnormal_fetal_growth/weight/0.35457081
106MP0003638_abnormal_response/metabolism_0.35023684
107MP0000432_abnormal_head_morphology0.34995164
108MP0001188_hyperpigmentation0.34367095
109MP0006054_spinal_hemorrhage0.34343735
110MP0000003_abnormal_adipose_tissue0.34286063
111MP0001881_abnormal_mammary_gland0.33810327
112MP0001661_extended_life_span0.33133141
113MP0003950_abnormal_plasma_membrane0.32613999
114MP0003938_abnormal_ear_development0.31682290
115MP0003806_abnormal_nucleotide_metabolis0.31541356
116MP0003448_altered_tumor_morphology0.31533250
117MP0005375_adipose_tissue_phenotype0.30925844
118MP0002090_abnormal_vision0.30700438
119MP0001765_abnormal_ion_homeostasis0.30359788
120MP0000013_abnormal_adipose_tissue0.29114589
121MP0004883_abnormal_blood_vessel0.28924962
122MP0003385_abnormal_body_wall0.28049587
123MP0005390_skeleton_phenotype0.27864350
124MP0003300_gastrointestinal_ulcer0.27626932
125MP0002896_abnormal_bone_mineralization0.26746082
126MP0000372_irregular_coat_pigmentation0.26269275
127MP0003936_abnormal_reproductive_system0.26053372
128MP0001666_abnormal_nutrient_absorption0.25422883
129MP0000750_abnormal_muscle_regeneration0.24760752
130MP0005165_increased_susceptibility_to0.23317849
131MP0002109_abnormal_limb_morphology0.22614958

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)7.65255723
2Plantar hyperkeratosis (HP:0007556)6.64776441
3Onycholysis (HP:0001806)6.60933086
4Woolly hair (HP:0002224)6.57064591
5Fragile nails (HP:0001808)6.42486754
6Right ventricular cardiomyopathy (HP:0011663)6.18162769
7Increased IgE level (HP:0003212)5.95578023
8Palmoplantar hyperkeratosis (HP:0000972)5.71402134
9Congenital ichthyosiform erythroderma (HP:0007431)5.71354394
10Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.68104670
11Milia (HP:0001056)5.58961217
12Lip pit (HP:0100267)5.49322544
13Parakeratosis (HP:0001036)5.41674163
14Palmar hyperkeratosis (HP:0010765)5.40913415
15Abnormality of nail color (HP:0100643)5.24550744
16Erythema (HP:0010783)4.88467232
17Erythroderma (HP:0001019)4.55666722
18Pili torti (HP:0003777)4.45891641
19Abnormality of the axillary hair (HP:0100134)4.41233987
20Abnormality of secondary sexual hair (HP:0009888)4.41233987
21Thick nail (HP:0001805)4.36327176
22Abnormal blistering of the skin (HP:0008066)4.21215498
23Nail dystrophy (HP:0008404)4.05434537
24Oral leukoplakia (HP:0002745)3.90579720
25Selective tooth agenesis (HP:0001592)3.76015147
26Sparse scalp hair (HP:0002209)3.60563070
27Atrophic scars (HP:0001075)3.56573428
28Popliteal pterygium (HP:0009756)3.42787664
29Sparse eyelashes (HP:0000653)3.40087274
30Abnormality of placental membranes (HP:0011409)3.35298570
31Amniotic constriction ring (HP:0009775)3.35298570
32Hypohidrosis (HP:0000966)3.34503459
33Curly hair (HP:0002212)3.33245182
34Alopecia of scalp (HP:0002293)3.31327573
35Dry hair (HP:0011359)3.30664061
36Conjunctival hamartoma (HP:0100780)3.30451056
37Ectropion (HP:0000656)3.29190594
38Corneal erosion (HP:0200020)3.27268053
39Natal tooth (HP:0000695)3.19173426
40Advanced eruption of teeth (HP:0006288)3.12448487
41Acanthosis nigricans (HP:0000956)3.11870287
42Ventricular tachycardia (HP:0004756)3.07466675
43Hyporeflexia of lower limbs (HP:0002600)3.04682336
44Concave nail (HP:0001598)3.01023875
45Ankyloglossia (HP:0010296)2.99648332
46Absent eyelashes (HP:0000561)2.97598711
47Ridged nail (HP:0001807)2.92028823
48Palmoplantar keratoderma (HP:0000982)2.83097675
49Abnormal hair laboratory examination (HP:0003328)2.82529847
50Distal lower limb muscle weakness (HP:0009053)2.79286444
51Pruritus (HP:0000989)2.78461337
52Gangrene (HP:0100758)2.74095037
53Abnormality of cells of the erythroid lineage (HP:0012130)2.70705971
54Aplasia cutis congenita (HP:0001057)2.69584929
55Brittle hair (HP:0002299)2.58284921
56Abnormality of the salivary glands (HP:0010286)2.55144212
57Abnormal hemoglobin (HP:0011902)2.54738690
58Carious teeth (HP:0000670)2.54552853
59Congenital, generalized hypertrichosis (HP:0004540)2.53129970
60Hypoplastic labia majora (HP:0000059)2.48655767
61Reticulocytopenia (HP:0001896)2.47637914
62Pterygium (HP:0001059)2.40413549
63Xerostomia (HP:0000217)2.33718163
64Abnormality of oral frenula (HP:0000190)2.32960272
65Abnormality of the labia majora (HP:0012881)2.25454963
66Abnormality of the gastric mucosa (HP:0004295)2.22356291
67Hypoplasia of dental enamel (HP:0006297)2.19389033
68Abnormal number of erythroid precursors (HP:0012131)2.16080767
69Abnormality of the fingernails (HP:0001231)2.14842166
70Anhidrosis (HP:0000970)2.13542614
71Abnormality of the neuromuscular junction (HP:0003398)2.10618556
72Fatigable weakness (HP:0003473)2.10618556
73Oligodontia (HP:0000677)2.07512747
74Dehydration (HP:0001944)2.03816634
75Aplasia involving bones of the extremities (HP:0009825)2.03645910
76Aplasia involving bones of the upper limbs (HP:0009823)2.03645910
77Aplasia of the phalanges of the hand (HP:0009802)2.03645910
78Conical tooth (HP:0000698)2.00799522
79Areflexia of lower limbs (HP:0002522)2.00522182
80Blepharitis (HP:0000498)2.00362236
81Amelogenesis imperfecta (HP:0000705)2.00184169
82Hypodontia (HP:0000668)1.97183336
83Septate vagina (HP:0001153)1.95966115
84Absent hair (HP:0002298)1.94508087
85Cheilitis (HP:0100825)1.94285284
86Fragile skin (HP:0001030)1.93004387
87Absent eyebrow (HP:0002223)1.92035945
88Ventricular fibrillation (HP:0001663)1.90272162
89Dry skin (HP:0000958)1.88643716
90Synostosis involving the elbow (HP:0003938)1.88112879
91Humeroradial synostosis (HP:0003041)1.88112879
92Epidermoid cyst (HP:0200040)1.86575166
93Down-sloping shoulders (HP:0200021)1.85593823
94Macrocytic anemia (HP:0001972)1.85303955
95Split foot (HP:0001839)1.84679392
96Stenosis of the external auditory canal (HP:0000402)1.84409874
97Nasolacrimal duct obstruction (HP:0000579)1.82115986
98Breast hypoplasia (HP:0003187)1.81362990
99Abnormality of permanent molar morphology (HP:0011071)1.81292277
100Abnormality of the dental root (HP:0006486)1.81292277
101Taurodontia (HP:0000679)1.81292277
102Severe Myopia (HP:0011003)1.78060107
103Labial hypoplasia (HP:0000066)1.77164672
104Hamartoma of the eye (HP:0010568)1.76562157
105Pustule (HP:0200039)1.74765285
106Hyperhidrosis (HP:0000975)1.74652642
107Skin ulcer (HP:0200042)1.74528716
108Hypergammaglobulinemia (HP:0010702)1.72523707
109Trismus (HP:0000211)1.69527694
110Multifactorial inheritance (HP:0001426)1.69498169
111Periodontitis (HP:0000704)1.67926796
112Anonychia (HP:0001798)1.67905934
113Pallor (HP:0000980)1.67482206
114Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.65972928
115Hoarse voice (HP:0001609)1.65428151
116Abnormality of hair growth rate (HP:0011363)1.65415376
117Slow-growing hair (HP:0002217)1.65415376
118Hypoplastic female external genitalia (HP:0012815)1.65193609
119Abnormality of molar morphology (HP:0011070)1.65073035
120Abnormality of molar (HP:0011077)1.65073035
121Corneal dystrophy (HP:0001131)1.61476600
122Follicular hyperkeratosis (HP:0007502)1.61294680
123Autoamputation (HP:0001218)1.61213304
124Bifid scrotum (HP:0000048)1.60276514
125Poikiloderma (HP:0001029)1.59986987
126Achilles tendon contracture (HP:0001771)1.59958027
127Skin pits (HP:0100276)1.59589623
128Esophageal atresia (HP:0002032)1.56324813
129Abnormality of the dental pulp (HP:0006479)1.55445398
130Laryngomalacia (HP:0001601)1.53867547
131Death in infancy (HP:0001522)1.52202845
132Hypoplasia of the uterus (HP:0000013)1.51965830
133Premature loss of primary teeth (HP:0006323)1.51873600
134Ulnar claw (HP:0001178)1.50770582
135Sudden death (HP:0001699)1.49826875
136Neonatal death (HP:0003811)1.49713516
137Abnormality of the 2nd finger (HP:0004100)1.49643064
138Squamous cell carcinoma (HP:0002860)1.48559123

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.35317116
2MAPKAPK34.76516540
3MST44.57016272
4MAP3K34.10606417
5FER3.90242015
6ARAF3.49129011
7RPS6KB22.77010625
8NTRK12.55693571
9MAP3K22.43130087
10TRPM72.23098838
11STK242.21461632
12PIM22.17535549
13LATS12.07937834
14LMTK22.02308780
15EPHB22.01580980
16EPHA22.01147681
17ERN11.95557242
18MET1.81169678
19LRRK21.77166916
20FLT31.77148931
21BCR1.70754560
22EPHA31.68936488
23PIK3CG1.65432469
24FGFR21.64176803
25PAK41.63844119
26PDGFRA1.61826770
27STK101.55233951
28MAP3K121.54479450
29PTK61.38412926
30MAPKAPK51.37879738
31ERBB31.37242789
32PBK1.34627202
33KSR21.28086884
34IRAK31.24378450
35TESK11.23747191
36CDK121.23731990
37BLK1.15974480
38FGFR41.14552900
39BMPR1B1.12080615
40CDK61.07786881
41DYRK1B1.06183907
42BRAF1.06046360
43MAP3K11.05823428
44EEF2K1.01594054
45MAP3K141.00338757
46RAF10.98761720
47EPHB10.98394762
48MOS0.97747798
49TGFBR20.95676618
50MAP3K110.92585379
51GRK10.86741035
52MAPKAPK20.81853547
53FGFR30.81753582
54MAP2K60.81045199
55TYK20.80167693
56RPS6KA40.80070457
57MAP3K70.79455542
58TAOK10.79301501
59PDGFRB0.77656307
60MAP3K130.77417559
61NME10.74323981
62DMPK0.74032423
63BMX0.69271645
64MAPK150.68069342
65NTRK20.66619870
66FRK0.65961824
67SIK30.65930630
68CDK30.64138807
69MAP2K20.64033233
70KSR10.62395668
71GRK70.62223946
72RIPK10.61395945
73SMG10.60905076
74TNK20.59936944
75NME20.57186012
76PRPF4B0.56609015
77ILK0.56410686
78PTK20.56198905
79NEK60.54933689
80TTN0.54553469
81TRIB30.54469135
82LATS20.52733389
83PRKD10.52621368
84STK380.51347512
85CASK0.51092480
86EPHA40.50315428
87FGFR10.50300267
88PRKCI0.48832689
89ROCK20.48608640
90NEK10.48544695
91BMPR20.47368258
92ITK0.47021564
93EIF2AK20.45919491
94EIF2AK30.45832379
95IKBKB0.45823885
96RIPK40.45664382
97MAP2K10.43926677
98SIK10.43854364
99MAP3K90.43754866
100SCYL20.42944582
101CDK190.42823043
102ERBB20.42728633
103ROCK10.42233181
104OBSCN0.41509877
105LIMK10.41334673
106RPS6KA10.40850969
107ADRBK10.40130169
108RPS6KA20.38533667
109IKBKE0.38193278
110MAP3K80.38181411
111PRKCE0.37814440
112RPS6KB10.36693495
113STK110.36359986
114ABL20.36305326
115RPS6KL10.36268547
116RPS6KC10.36268547
117PKN10.33414720
118HIPK20.32738389
119CHUK0.32653082
120RET0.32605630
121NLK0.30433111
122MTOR0.29966162
123MAP3K60.29328197
124CSNK1D0.28871815
125JAK20.28454392
126STK30.28384330
127CSF1R0.28231774
128PHKG10.27684725
129PHKG20.27684725
130IGF1R0.27258015
131ICK0.27171161
132TGFBR10.26607395
133ERBB40.26522308
134STK38L0.26162921
135PAK30.25544777
136RPS6KA60.25142694
137JAK30.24212745
138EIF2AK10.24189861
139MAPK70.20217634
140GSK3A0.19478185
141INSR0.18496376
142TSSK60.17818777
143ABL10.17799947
144PAK20.16104747

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.34171701
2Cyanoamino acid metabolism_Homo sapiens_hsa004603.50818522
3Sphingolipid metabolism_Homo sapiens_hsa006003.27367222
4Linoleic acid metabolism_Homo sapiens_hsa005912.90737831
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.81614184
6Arachidonic acid metabolism_Homo sapiens_hsa005902.58473089
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.49647370
8Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.46041608
9Fatty acid elongation_Homo sapiens_hsa000622.39523042
10Retinol metabolism_Homo sapiens_hsa008302.29131518
11Phenylalanine metabolism_Homo sapiens_hsa003602.19620873
12Basal cell carcinoma_Homo sapiens_hsa052172.08185260
13Histidine metabolism_Homo sapiens_hsa003401.88858548
14Ether lipid metabolism_Homo sapiens_hsa005651.72888161
15ECM-receptor interaction_Homo sapiens_hsa045121.66439288
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.64032207
17Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.63958746
18* p53 signaling pathway_Homo sapiens_hsa041151.63495042
19Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.60918778
20Adherens junction_Homo sapiens_hsa045201.59663411
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.57785252
22Caffeine metabolism_Homo sapiens_hsa002321.46187601
23Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.44311913
24Central carbon metabolism in cancer_Homo sapiens_hsa052301.43860416
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.42822484
26Tight junction_Homo sapiens_hsa045301.42479826
27Chemical carcinogenesis_Homo sapiens_hsa052041.40320330
28Axon guidance_Homo sapiens_hsa043601.38046015
29Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.36558473
30Hippo signaling pathway_Homo sapiens_hsa043901.31598371
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.26497507
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.26222377
33VEGF signaling pathway_Homo sapiens_hsa043701.22842341
34Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.20586580
35Tyrosine metabolism_Homo sapiens_hsa003501.20416861
36Proteoglycans in cancer_Homo sapiens_hsa052051.19144255
37Hedgehog signaling pathway_Homo sapiens_hsa043401.18332102
38Amoebiasis_Homo sapiens_hsa051461.16564933
39Chronic myeloid leukemia_Homo sapiens_hsa052201.16418403
40Bladder cancer_Homo sapiens_hsa052191.16091367
41Melanogenesis_Homo sapiens_hsa049161.15265823
42Pancreatic cancer_Homo sapiens_hsa052121.15177229
43Renal cell carcinoma_Homo sapiens_hsa052111.12250192
44Glioma_Homo sapiens_hsa052141.10792373
45Sphingolipid signaling pathway_Homo sapiens_hsa040711.09283346
46Inositol phosphate metabolism_Homo sapiens_hsa005621.04852044
47Dilated cardiomyopathy_Homo sapiens_hsa054141.03439375
48Shigellosis_Homo sapiens_hsa051311.03359297
49PI3K-Akt signaling pathway_Homo sapiens_hsa041511.01472741
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97765360
51Fatty acid biosynthesis_Homo sapiens_hsa000610.96582611
52Pancreatic secretion_Homo sapiens_hsa049720.95700222
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.95681145
54TGF-beta signaling pathway_Homo sapiens_hsa043500.93808228
55Toxoplasmosis_Homo sapiens_hsa051450.90593477
56Renin secretion_Homo sapiens_hsa049240.90032317
57Mineral absorption_Homo sapiens_hsa049780.88984433
58GnRH signaling pathway_Homo sapiens_hsa049120.85887638
59Fat digestion and absorption_Homo sapiens_hsa049750.83471019
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.82413392
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82123114
62Insulin signaling pathway_Homo sapiens_hsa049100.81946340
63Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.81921146
64Phototransduction_Homo sapiens_hsa047440.79316769
65Prion diseases_Homo sapiens_hsa050200.79308024
66Ras signaling pathway_Homo sapiens_hsa040140.78058311
67Small cell lung cancer_Homo sapiens_hsa052220.78028251
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.77280594
69Wnt signaling pathway_Homo sapiens_hsa043100.77081862
70Staphylococcus aureus infection_Homo sapiens_hsa051500.77046867
71Hepatitis C_Homo sapiens_hsa051600.76636142
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.74566888
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.73986204
74Thyroid cancer_Homo sapiens_hsa052160.73680581
75Jak-STAT signaling pathway_Homo sapiens_hsa046300.73385910
76Dorso-ventral axis formation_Homo sapiens_hsa043200.72364678
77Serotonergic synapse_Homo sapiens_hsa047260.68356752
78ErbB signaling pathway_Homo sapiens_hsa040120.65480471
79Steroid biosynthesis_Homo sapiens_hsa001000.63971260
80Apoptosis_Homo sapiens_hsa042100.62894222
81Arginine biosynthesis_Homo sapiens_hsa002200.61709112
82Non-small cell lung cancer_Homo sapiens_hsa052230.61356629
83Pertussis_Homo sapiens_hsa051330.60965085
84Galactose metabolism_Homo sapiens_hsa000520.60830312
85Platelet activation_Homo sapiens_hsa046110.60429246
86beta-Alanine metabolism_Homo sapiens_hsa004100.60180809
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60054765
88Melanoma_Homo sapiens_hsa052180.59819295
89Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.59313221
90Protein digestion and absorption_Homo sapiens_hsa049740.57796495
91Estrogen signaling pathway_Homo sapiens_hsa049150.56266046
92Glycerolipid metabolism_Homo sapiens_hsa005610.56140112
93ABC transporters_Homo sapiens_hsa020100.55943169
94Rap1 signaling pathway_Homo sapiens_hsa040150.53895070
95Choline metabolism in cancer_Homo sapiens_hsa052310.52857258
96Long-term depression_Homo sapiens_hsa047300.52790922
97Pathways in cancer_Homo sapiens_hsa052000.52453011
98Gastric acid secretion_Homo sapiens_hsa049710.51877169
99Vascular smooth muscle contraction_Homo sapiens_hsa042700.51550993
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.50827430
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50333939
102Focal adhesion_Homo sapiens_hsa045100.50075342
103Ovarian steroidogenesis_Homo sapiens_hsa049130.49131344
104Adipocytokine signaling pathway_Homo sapiens_hsa049200.45809592
105* MicroRNAs in cancer_Homo sapiens_hsa052060.45677244
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45384939
107Acute myeloid leukemia_Homo sapiens_hsa052210.45203877
108NOD-like receptor signaling pathway_Homo sapiens_hsa046210.44219373
109Salivary secretion_Homo sapiens_hsa049700.43265801
110AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43116202
111Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.42522482
112Glutathione metabolism_Homo sapiens_hsa004800.40878609
113Neurotrophin signaling pathway_Homo sapiens_hsa047220.39772593
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.39350201
115Endometrial cancer_Homo sapiens_hsa052130.39215305
116Sulfur metabolism_Homo sapiens_hsa009200.38916016
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38821624
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38554337
119Malaria_Homo sapiens_hsa051440.38337127
120Collecting duct acid secretion_Homo sapiens_hsa049660.37745197
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37396708
122Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.37261119
123N-Glycan biosynthesis_Homo sapiens_hsa005100.36132406
124Notch signaling pathway_Homo sapiens_hsa043300.36040667
125Prostate cancer_Homo sapiens_hsa052150.35982630
126T cell receptor signaling pathway_Homo sapiens_hsa046600.35355680
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.34722441
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34597318
129Insulin resistance_Homo sapiens_hsa049310.34186312
130TNF signaling pathway_Homo sapiens_hsa046680.33600147
131Endocytosis_Homo sapiens_hsa041440.33575616
132Glucagon signaling pathway_Homo sapiens_hsa049220.32886215
133PPAR signaling pathway_Homo sapiens_hsa033200.32328968
134Salmonella infection_Homo sapiens_hsa051320.32046145
135Circadian rhythm_Homo sapiens_hsa047100.31704572
136Gap junction_Homo sapiens_hsa045400.31510739
137Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30512866

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