SERTAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of vitamin D biosynthetic process (GO:0060556)5.41042839
2negative regulation of interleukin-12 production (GO:0032695)4.37779188
3positive regulation of chemokine biosynthetic process (GO:0045080)4.28920951
4cellular response to arsenic-containing substance (GO:0071243)4.20538532
5regulation of vitamin metabolic process (GO:0030656)4.12767934
6negative regulation of nitric oxide biosynthetic process (GO:0045019)3.83233481
7response to xenobiotic stimulus (GO:0009410)3.77387268
8regulation of somitogenesis (GO:0014807)3.76223477
9negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.72619319
10regulation of chemokine biosynthetic process (GO:0045073)3.67871718
11oligosaccharide catabolic process (GO:0009313)3.67476019
12regulation of cytokine secretion involved in immune response (GO:0002739)3.63990715
13regulation of podosome assembly (GO:0071801)3.58528895
14regulation of chronic inflammatory response (GO:0002676)3.50986474
15cellular response to type I interferon (GO:0071357)3.50359641
16type I interferon signaling pathway (GO:0060337)3.50359641
17positive regulation of heat generation (GO:0031652)3.49366036
18positive regulation of lymphocyte apoptotic process (GO:0070230)3.48479306
19response to type I interferon (GO:0034340)3.46491809
20regulation of RIG-I signaling pathway (GO:0039535)3.38906246
21negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.30349354
22NIK/NF-kappaB signaling (GO:0038061)3.28782730
23regulation of interleukin-12 biosynthetic process (GO:0045075)3.26437501
24amino sugar catabolic process (GO:0046348)3.25689418
25antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.23613304
26branching involved in labyrinthine layer morphogenesis (GO:0060670)3.22037372
27negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.20847664
28response to peptidoglycan (GO:0032494)3.19979205
29glycosphingolipid catabolic process (GO:0046479)3.19127018
30regulation of retinoic acid receptor signaling pathway (GO:0048385)3.15147515
31positive regulation of NF-kappaB import into nucleus (GO:0042346)3.14195745
32regulation of fever generation (GO:0031620)3.12573578
33positive regulation of interferon-beta production (GO:0032728)3.12032772
34eosinophil chemotaxis (GO:0048245)3.07298274
35antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.06118900
36antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.06118900
37positive regulation of interferon-alpha production (GO:0032727)3.04745258
38positive regulation by symbiont of host defense response (GO:0052509)3.04371719
39modulation by symbiont of host defense response (GO:0052031)3.04371719
40modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.04371719
41modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.04371719
42positive regulation by organism of defense response of other organism involved in symbiotic interact3.04371719
43modulation by symbiont of host immune response (GO:0052553)3.04371719
44response to interferon-beta (GO:0035456)3.02661887
45regulation of membrane protein ectodomain proteolysis (GO:0051043)2.97872536
46positive regulation of prostaglandin secretion (GO:0032308)2.96503067
47antigen processing and presentation of endogenous antigen (GO:0019883)2.96340994
48response to muramyl dipeptide (GO:0032495)2.93452430
49decidualization (GO:0046697)2.90305210
50negative regulation of cytokine production involved in immune response (GO:0002719)2.89452743
51positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.88740582
52immunoglobulin mediated immune response (GO:0016064)2.88287283
53regulation of immunoglobulin secretion (GO:0051023)2.87864029
54regulation of interferon-alpha production (GO:0032647)2.87236479
55N-acetylneuraminate metabolic process (GO:0006054)2.85329027
56membrane lipid catabolic process (GO:0046466)2.84957880
57defense response to protozoan (GO:0042832)2.84887667
58interferon-gamma-mediated signaling pathway (GO:0060333)2.84187523
59response to arsenic-containing substance (GO:0046685)2.83955402
60glycolipid catabolic process (GO:0019377)2.83874636
61regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.83046984
62regulation of T-helper 1 cell differentiation (GO:0045625)2.81099739
63sphingosine metabolic process (GO:0006670)2.79408459
64lipoxygenase pathway (GO:0019372)2.79212587
65sphingolipid catabolic process (GO:0030149)2.78841670
66ribosomal small subunit assembly (GO:0000028)2.77547505
67positive regulation of interleukin-6 production (GO:0032755)2.76813935
68regulation of nitric oxide biosynthetic process (GO:0045428)2.76532632
69positive regulation of monocyte chemotaxis (GO:0090026)2.76307639
70regulation of heat generation (GO:0031650)2.74978900
71negative regulation of lipid storage (GO:0010888)2.74352441
72lipopolysaccharide-mediated signaling pathway (GO:0031663)2.71727755
73myeloid dendritic cell differentiation (GO:0043011)2.69704517
74myeloid dendritic cell activation (GO:0001773)2.69325649
75adhesion of symbiont to host cell (GO:0044650)2.68180086
76virion attachment to host cell (GO:0019062)2.68180086
77negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.67616413
78regulation of inflammatory response to antigenic stimulus (GO:0002861)2.67480294
79wound healing, spreading of epidermal cells (GO:0035313)2.67040090
80ceramide catabolic process (GO:0046514)2.66169226
81cellular response to interferon-beta (GO:0035458)2.66057784
82regulation of interleukin-6 production (GO:0032675)2.65689844
83G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.65527850
84hepatocyte apoptotic process (GO:0097284)2.64970978
85positive regulation of p38MAPK cascade (GO:1900745)2.64183300
86eosinophil migration (GO:0072677)2.63789542
87response to interferon-alpha (GO:0035455)2.63103344
88positive regulation of antigen processing and presentation (GO:0002579)2.62535981
89response to progesterone (GO:0032570)2.62456081
90endothelial tube morphogenesis (GO:0061154)2.62138924
91morphogenesis of an endothelium (GO:0003159)2.62138924
92cellular response to virus (GO:0098586)2.62089336
93regulation of B cell receptor signaling pathway (GO:0050855)2.61313545
94positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.61135750
95diol metabolic process (GO:0034311)2.60600495
96neutrophil activation involved in immune response (GO:0002283)2.59697485
97granulocyte activation (GO:0036230)2.56729293
98regulation of prostaglandin secretion (GO:0032306)2.55371615
99regulation of interleukin-12 production (GO:0032655)2.55047813
100negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.54645349
101regulation of dendritic cell antigen processing and presentation (GO:0002604)2.54550726
102germinal center formation (GO:0002467)2.54038394
103T cell apoptotic process (GO:0070231)2.53554219
104negative regulation of tumor necrosis factor production (GO:0032720)2.53065418
105positive regulation of leukocyte apoptotic process (GO:2000108)2.52937192
106regulation of interferon-beta biosynthetic process (GO:0045357)2.52571939
107regulation of mononuclear cell migration (GO:0071675)2.51978255
108regulation of NF-kappaB import into nucleus (GO:0042345)2.51684074
109cellular response to lipopolysaccharide (GO:0071222)2.50863103
110regulation of T cell chemotaxis (GO:0010819)2.50476573
111positive regulation of T cell chemotaxis (GO:0010820)2.50476573
112positive regulation of nitric oxide biosynthetic process (GO:0045429)2.50275894
113production of molecular mediator involved in inflammatory response (GO:0002532)2.50042726
114activation of MAPKKK activity (GO:0000185)2.49821023
115glomerular visceral epithelial cell development (GO:0072015)2.48985884
116positive regulation of gamma-delta T cell activation (GO:0046645)2.48122876
117positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.47911069
118regulation of interferon-beta production (GO:0032648)2.47773702
119negative regulation of myeloid cell apoptotic process (GO:0033033)2.47484131
120regulation of response to interferon-gamma (GO:0060330)2.46888720
121negative regulation of interleukin-6 production (GO:0032715)2.45121531
122cellular response to thyroid hormone stimulus (GO:0097067)2.44935761
123monocyte chemotaxis (GO:0002548)2.43684432
124negative regulation of mast cell activation (GO:0033004)2.43444493
125low-density lipoprotein particle clearance (GO:0034383)2.43337925
126negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)2.43190559
127response to laminar fluid shear stress (GO:0034616)2.41560004
128cellular response to molecule of bacterial origin (GO:0071219)2.41434445
129positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.41383085
130regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.40750023
131positive regulation of calcium ion import (GO:0090280)2.40090061
132modulation by symbiont of host cellular process (GO:0044068)2.39968962
133sphingoid metabolic process (GO:0046519)2.39522894
134endothelial cell chemotaxis (GO:0035767)2.39227673
135regulation of type I interferon-mediated signaling pathway (GO:0060338)2.39111053
136positive regulation of interleukin-12 production (GO:0032735)2.39066878
137regulation of apoptotic process involved in morphogenesis (GO:1902337)2.38506434
138regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)2.37971458
139regulation of antigen processing and presentation (GO:0002577)2.37175410
140positive regulation of type I interferon production (GO:0032481)2.37121217
141positive regulation of T cell migration (GO:2000406)2.35929045
142leukocyte apoptotic process (GO:0071887)2.34613890
143cellular response to interferon-alpha (GO:0035457)2.33563128
144heparin metabolic process (GO:0030202)2.31759497
145heparin biosynthetic process (GO:0030210)2.31759497
146positive regulation of natural killer cell differentiation (GO:0032825)2.31654657
147chaperone mediated protein folding requiring cofactor (GO:0051085)2.31180214
148positive regulation of protein homooligomerization (GO:0032464)2.30955631
149negative regulation of viral genome replication (GO:0045071)2.30547628
150natural killer cell mediated cytotoxicity (GO:0042267)2.29903427
151natural killer cell mediated immunity (GO:0002228)2.29903427
152I-kappaB kinase/NF-kappaB signaling (GO:0007249)2.29146454
153regulation of protein import into nucleus, translocation (GO:0033158)2.28923512
154regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.28175173
155regulation of T cell migration (GO:2000404)2.27702567
156positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.27173743
157wound healing, spreading of cells (GO:0044319)2.26266513
158cellular response to interferon-gamma (GO:0071346)2.21930629
159lymphocyte apoptotic process (GO:0070227)2.21407799
160response to protozoan (GO:0001562)2.20916927
161detection of molecule of bacterial origin (GO:0032490)2.20878861
162ribosomal small subunit biogenesis (GO:0042274)2.20403504
163B cell mediated immunity (GO:0019724)2.19978804
164positive regulation of T cell apoptotic process (GO:0070234)2.19210310
165angiogenesis involved in wound healing (GO:0060055)2.19013177
166maturation of SSU-rRNA (GO:0030490)2.18304076
167viral transcription (GO:0019083)2.17811822
168dendritic cell differentiation (GO:0097028)2.16539432
169lipopolysaccharide biosynthetic process (GO:0009103)2.16369965
170regulation of interleukin-8 biosynthetic process (GO:0045414)2.15778111
171macrophage activation involved in immune response (GO:0002281)2.15674102
172T-helper 1 type immune response (GO:0042088)2.14483230
173positive regulation of protein oligomerization (GO:0032461)2.14310207
174folic acid transport (GO:0015884)2.13188251
175regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.12849966

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.55383290
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.00595149
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.61204716
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.21462740
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.10199261
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.93470528
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.85794436
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.84138925
9RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.48241400
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.39804448
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.23425369
12STAT4_19710469_ChIP-ChIP_TH1__Mouse2.22555030
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.20524999
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.14729844
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.13152936
16RARG_19884340_ChIP-ChIP_MEFs_Mouse2.11679026
17* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.11122194
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.09025849
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.99164258
20CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.98076020
21NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.94411397
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.93109356
23IRF8_27001747_Chip-Seq_BMDM_Mouse1.92286423
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.89044687
25* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.88981823
26NOTCH1_21737748_ChIP-Seq_TLL_Human1.76830038
27SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.73130164
28TRIM28_21343339_ChIP-Seq_HEK293_Human1.72619666
29ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.71786323
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.67215073
31FOXM1_23109430_ChIP-Seq_U2OS_Human1.67141619
32* ELK3_25401928_ChIP-Seq_HUVEC_Human1.66477284
33SPI1_23547873_ChIP-Seq_NB4_Human1.64987351
34GATA1_22025678_ChIP-Seq_K562_Human1.63460154
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.57470258
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57465396
37ESR1_21235772_ChIP-Seq_MCF-7_Human1.56754178
38NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.56668651
39TFEB_21752829_ChIP-Seq_HELA_Human1.56256192
40MAF_26560356_Chip-Seq_TH1_Human1.55773750
41LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52163824
42* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.51113457
43SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.49753581
44SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.49753581
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.49097852
46VDR_24787735_ChIP-Seq_THP-1_Human1.48365823
47* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.47314702
48RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.45787348
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.45143811
50HIF1A_21447827_ChIP-Seq_MCF-7_Human1.44210689
51* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43383971
52VDR_24763502_ChIP-Seq_THP-1_Human1.41444642
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.40550187
54CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.40140472
55JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39429576
56VDR_21846776_ChIP-Seq_THP-1_Human1.38120710
57HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.37346288
58STAT3_1855785_ChIP-Seq_MESCs_Mouse1.36558807
59STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.33497355
60GABP_17652178_ChIP-ChIP_JURKAT_Human1.33018636
61Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.32869496
62* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.32814346
63ZNF263_19887448_ChIP-Seq_K562_Human1.30937997
64MYB_26560356_Chip-Seq_TH1_Human1.30844431
65CLOCK_20551151_ChIP-Seq_293T_Human1.30814037
66E2F7_22180533_ChIP-Seq_HELA_Human1.30603245
67RUNX1_22412390_ChIP-Seq_EML_Mouse1.30529366
68* MYB_26560356_Chip-Seq_TH2_Human1.27228734
69GATA2_21666600_ChIP-Seq_HMVEC_Human1.26924015
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23139578
71* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.22234123
72* STAT1_20625510_ChIP-Seq_HELA_Human1.21606962
73E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.21408492
74FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.20126446
75SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.17716666
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17707212
77BCL6_27268052_Chip-Seq_Bcells_Human1.16951991
78SCL_19346495_ChIP-Seq_HPC-7_Human1.16687432
79TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16087816
80* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.15318701
81XRN2_22483619_ChIP-Seq_HELA_Human1.15239404
82UTX_26944678_Chip-Seq_JUKART_Human1.14565665
83ELF1_17652178_ChIP-ChIP_JURKAT_Human1.14415070
84CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13326515
85CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13064168
86* SOX2_20726797_ChIP-Seq_SW620_Human1.12917083
87KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.12748260
88KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.12748260
89KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.12748260
90* ELK1_22589737_ChIP-Seq_MCF10A_Human1.12159530
91LXR_22292898_ChIP-Seq_THP-1_Human1.11760362
92PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09370592
93* BCOR_27268052_Chip-Seq_Bcells_Human1.08900617
94RUNX_20019798_ChIP-Seq_JUKART_Human1.08492911
95* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08435441
96KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.07538094
97* TCF7_22412390_ChIP-Seq_EML_Mouse1.07319009
98MYC_22102868_ChIP-Seq_BL_Human1.07282000
99LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.06681281
100ATF3_27146783_Chip-Seq_COLON_Human1.06182397
101* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.05303667
102* ELF1_20517297_ChIP-Seq_JURKAT_Human1.04262872
103MAF_26560356_Chip-Seq_TH2_Human1.03598161
104UBF1/2_26484160_Chip-Seq_HMECs_Human1.03352614
105FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.03246542
106CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03104853
107PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02439552
108SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98671933
109CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.98154538
110TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.97839750
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97677559
112SMAD_19615063_ChIP-ChIP_OVARY_Human0.97109412
113RACK7_27058665_Chip-Seq_MCF-7_Human0.96732188
114ETS1_20019798_ChIP-Seq_JURKAT_Human0.96532823
115KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96279712
116CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96251383
117DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95986093
118PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95850840
119SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95346197
120P63_26484246_Chip-Seq_KERATINOCYTES_Human0.95311990
121KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94320121
122* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.93468670
123KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.93263184
124NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92936722
125PPARA_22158963_ChIP-Seq_LIVER_Mouse0.92281016
126DCP1A_22483619_ChIP-Seq_HELA_Human0.92251642
127* NCOR1_26117541_ChIP-Seq_K562_Human0.91935488
128SPI1_23127762_ChIP-Seq_K562_Human0.91501532
129* TP53_22127205_ChIP-Seq_IMR90_Human0.90786863
130MYC_18555785_ChIP-Seq_MESCs_Mouse0.90540680
131* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.89059647
132GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.88692262
133JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87775235
134FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.87348613
135CTCF_26484167_Chip-Seq_Bcells_Mouse0.85798476

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell4.12488971
2MP0005058_abnormal_lysosome_morphology3.95853968
3MP0003724_increased_susceptibility_to3.44600866
4MP0003806_abnormal_nucleotide_metabolis2.70406472
5MP0009785_altered_susceptibility_to2.66558838
6MP0001835_abnormal_antigen_presentation2.54653414
7MP0003436_decreased_susceptibility_to2.51681830
8MP0000685_abnormal_immune_system2.48312785
9MP0003828_pulmonary_edema2.17998222
10MP0003075_altered_response_to2.16781059
11MP0006082_CNS_inflammation2.16260151
12MP0002148_abnormal_hypersensitivity_rea2.13634491
13MP0003303_peritoneal_inflammation2.09250689
14MP0002139_abnormal_hepatobiliary_system2.06804368
15MP0005000_abnormal_immune_tolerance2.06190252
16MP0005387_immune_system_phenotype1.93683657
17MP0001790_abnormal_immune_system1.93683657
18MP0009278_abnormal_bone_marrow1.88364618
19MP0001800_abnormal_humoral_immune1.83717781
20MP0002452_abnormal_antigen_presenting1.83535871
21MP0004947_skin_inflammation1.79094605
22MP0005025_abnormal_response_to1.79046791
23MP0003279_aneurysm1.79024302
24MP0001545_abnormal_hematopoietic_system1.74827369
25MP0005397_hematopoietic_system_phenotyp1.74827369
26MP0002723_abnormal_immune_serum1.73110600
27MP0005671_abnormal_response_to1.73007018
28MP0003941_abnormal_skin_development1.71568405
29MP0002419_abnormal_innate_immunity1.71514681
30MP0010155_abnormal_intestine_physiology1.70010182
31MP0001533_abnormal_skeleton_physiology1.68777731
32MP0009333_abnormal_splenocyte_physiolog1.68154558
33MP0003763_abnormal_thymus_physiology1.64471587
34MP0002405_respiratory_system_inflammati1.62684372
35MP0003448_altered_tumor_morphology1.62024444
36MP0002138_abnormal_hepatobiliary_system1.61042516
37MP0001853_heart_inflammation1.59912243
38MP0000604_amyloidosis1.59198526
39MP0003453_abnormal_keratinocyte_physiol1.58344057
40MP0002420_abnormal_adaptive_immunity1.56875563
41MP0001819_abnormal_immune_cell1.56624774
42MP0010234_abnormal_vibrissa_follicle1.56491561
43MP0001873_stomach_inflammation1.55500618
44MP0000858_altered_metastatic_potential1.54460096
45MP0008438_abnormal_cutaneous_collagen1.54378668
46MP0005023_abnormal_wound_healing1.52376316
47MP0000465_gastrointestinal_hemorrhage1.51411907
48MP0005451_abnormal_body_composition1.49608377
49MP0008007_abnormal_cellular_replicative1.45553444
50MP0002166_altered_tumor_susceptibility1.43962919
51MP0005275_abnormal_skin_tensile1.43371592
52MP0004808_abnormal_hematopoietic_stem1.43290395
53MP0002332_abnormal_exercise_endurance1.42161553
54MP0010352_gastrointestinal_tract_polyps1.39212104
55MP0000750_abnormal_muscle_regeneration1.39112234
56MP0010368_abnormal_lymphatic_system1.38480690
57MP0004510_myositis1.38039319
58MP0002254_reproductive_system_inflammat1.37202268
59MP0003172_abnormal_lysosome_physiology1.35147617
60MP0005390_skeleton_phenotype1.35109262
61MP0002877_abnormal_melanocyte_morpholog1.34717287
62MP0002006_tumorigenesis1.33315039
63MP0002009_preneoplasia1.32920243
64MP0003195_calcinosis1.32616909
65MP0002398_abnormal_bone_marrow1.32216740
66MP0002132_abnormal_respiratory_system1.30869696
67MP0002060_abnormal_skin_morphology1.28111633
68MP0001845_abnormal_inflammatory_respons1.27302123
69MP0003705_abnormal_hypodermis_morpholog1.27080089
70MP0003950_abnormal_plasma_membrane1.26313663
71MP0003191_abnormal_cellular_cholesterol1.26311340
72MP0005464_abnormal_platelet_physiology1.25709967
73MP0005165_increased_susceptibility_to1.25392408
74MP0000716_abnormal_immune_system1.22721886
75MP0000767_abnormal_smooth_muscle1.22433194
76MP0005164_abnormal_response_to1.21258974
77MP0005310_abnormal_salivary_gland1.20812030
78MP0002933_joint_inflammation1.20494930
79MP0002722_abnormal_immune_system1.19881452
80MP0001542_abnormal_bone_strength1.19610551
81MP0001851_eye_inflammation1.19604809
82MP0008004_abnormal_stomach_pH1.19591618
83MP0004883_abnormal_blood_vessel1.18877797
84MP0009379_abnormal_foot_pigmentation1.18485081
85MP0003091_abnormal_cell_migration1.17759777
86MP0005076_abnormal_cell_differentiation1.17605696
87MP0000343_altered_response_to1.16852236
88MP0003566_abnormal_cell_adhesion1.15891674
89MP0002396_abnormal_hematopoietic_system1.15534468
90MP0009764_decreased_sensitivity_to1.14472782
91MP0010307_abnormal_tumor_latency1.14348932
92MP0000490_abnormal_crypts_of1.11866816
93MP0000689_abnormal_spleen_morphology1.09055179
94MP0002429_abnormal_blood_cell1.08528361
95MP0005167_abnormal_blood-brain_barrier1.06312949
96MP0006054_spinal_hemorrhage1.05770577
97MP0004782_abnormal_surfactant_physiolog1.03284025
98MP0002837_dystrophic_cardiac_calcinosis1.02282604
99MP0003693_abnormal_embryo_hatching1.01439558
100MP0001879_abnormal_lymphatic_vessel0.99453562
101MP0008469_abnormal_protein_level0.97675446
102MP0000249_abnormal_blood_vessel0.95276279
103MP0003866_abnormal_defecation0.95141933
104MP0003300_gastrointestinal_ulcer0.94797267
105MP0002277_abnormal_respiratory_mucosa0.94712241
106MP0005508_abnormal_skeleton_morphology0.94046596
107MP0009384_cardiac_valve_regurgitation0.93867017
108MP0003646_muscle_fatigue0.93831343
109MP0001216_abnormal_epidermal_layer0.93644447
110MP0003943_abnormal_hepatobiliary_system0.90829238
111MP0005166_decreased_susceptibility_to0.90319421
112MP0008875_abnormal_xenobiotic_pharmacok0.89922748
113MP0000703_abnormal_thymus_morphology0.89398692
114MP0005595_abnormal_vascular_smooth0.89373841
115MP0005367_renal/urinary_system_phenotyp0.88786485
116MP0000516_abnormal_urinary_system0.88786485
117MP0002796_impaired_skin_barrier0.88110872
118MP0002998_abnormal_bone_remodeling0.83951966
119MP0010030_abnormal_orbit_morphology0.83346269
120MP0003186_abnormal_redox_activity0.83155941
121MP0003656_abnormal_erythrocyte_physiolo0.83006188
122MP0003795_abnormal_bone_structure0.82552603
123MP0001191_abnormal_skin_condition0.79361604
124MP0008260_abnormal_autophagy0.77788775
125MP0009763_increased_sensitivity_to0.75787951
126MP0001764_abnormal_homeostasis0.73822113
127MP0001243_abnormal_dermal_layer0.71772529
128MP0001663_abnormal_digestive_system0.71100781
129MP0005647_abnormal_sex_gland0.70287957
130MP0001727_abnormal_embryo_implantation0.69487860
131MP0003221_abnormal_cardiomyocyte_apopto0.69054191
132MP0005319_abnormal_enzyme/_coenzyme0.67937339
133MP0003329_amyloid_beta_deposits0.64442283
134MP0002136_abnormal_kidney_physiology0.63012100

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of liposaccharide metabolism (HP:0010968)7.38663991
2Abnormality of glycosphingolipid metabolism (HP:0004343)7.38663991
3Abnormality of glycolipid metabolism (HP:0010969)7.38663991
4Increased cerebral lipofuscin (HP:0011813)4.49743735
5Dysostosis multiplex (HP:0000943)4.30661240
6Eczematoid dermatitis (HP:0000976)4.00503289
7Increased neuronal autofluorescent lipopigment (HP:0002074)3.94571182
8Loss of speech (HP:0002371)3.91651815
9Mutism (HP:0002300)3.78103375
10Myositis (HP:0100614)3.72473614
11Orchitis (HP:0100796)3.72016479
12Disinhibition (HP:0000734)3.66999756
13Recurrent abscess formation (HP:0002722)3.60669283
14Anomalous pulmonary venous return (HP:0010772)3.51466660
15Abnormality of mucopolysaccharide metabolism (HP:0011020)3.49691489
16Abnormality of polysaccharide metabolism (HP:0011012)3.49691489
17Abnormality of glycosaminoglycan metabolism (HP:0004371)3.49691489
18Elevated erythrocyte sedimentation rate (HP:0003565)3.41849161
19Nuclear cataract (HP:0100018)3.31760572
20Abnormality of the pulmonary veins (HP:0011718)3.30410575
21Recurrent bacterial skin infections (HP:0005406)3.29008908
22Pustule (HP:0200039)3.25108027
23Optic neuritis (HP:0100653)3.20817187
24Retrobulbar optic neuritis (HP:0100654)3.20817187
25Urinary glycosaminoglycan excretion (HP:0003541)3.11638296
26Mucopolysacchariduria (HP:0008155)3.11638296
27Increased serum ferritin (HP:0003281)3.02431881
28Parakeratosis (HP:0001036)2.98867342
29Hematochezia (HP:0002573)2.92499770
30Premature rupture of membranes (HP:0001788)2.81877058
31Nonimmune hydrops fetalis (HP:0001790)2.74190591
32Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.71947862
33Osteolytic defects of the hand bones (HP:0009699)2.71813971
34Osteolytic defects of the phalanges of the hand (HP:0009771)2.71813971
35Prolonged neonatal jaundice (HP:0006579)2.70586098
36Progressive neurologic deterioration (HP:0002344)2.64836194
37Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.62157730
38Prostate neoplasm (HP:0100787)2.61190802
39Autoimmune thrombocytopenia (HP:0001973)2.55686002
40Diaphragmatic weakness (HP:0009113)2.54248391
41Thick nail (HP:0001805)2.54038291
42Axonal loss (HP:0003447)2.50462090
43Abnormality of iron homeostasis (HP:0011031)2.48601533
44Protrusio acetabuli (HP:0003179)2.47724380
45Chronic otitis media (HP:0000389)2.42385563
46Neurofibrillary tangles (HP:0002185)2.40139553
47Nausea (HP:0002018)2.38745106
48Spontaneous hematomas (HP:0007420)2.38399423
49Glomerulonephritis (HP:0000099)2.36953665
50Abnormality of the nasal mucosa (HP:0000433)2.36568421
51Petechiae (HP:0000967)2.36353623
52Mediastinal lymphadenopathy (HP:0100721)2.35715538
53Increased IgM level (HP:0003496)2.35661786
54Polycythemia (HP:0001901)2.33340368
55Stomatitis (HP:0010280)2.31615956
56Amyloidosis (HP:0011034)2.31502129
57Thrombocytosis (HP:0001894)2.29736652
58Myocardial infarction (HP:0001658)2.29423250
59Metaphyseal irregularity (HP:0003025)2.28815428
60Malnutrition (HP:0004395)2.27283791
61Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.27278809
62Vertebral compression fractures (HP:0002953)2.27101753
63Mesangial abnormality (HP:0001966)2.26227145
64Upper motor neuron abnormality (HP:0002127)2.25491888
65Arterial thrombosis (HP:0004420)2.24274095
66Abnormality of the odontoid process (HP:0003310)2.24223449
67Abnormality of macrophages (HP:0004311)2.23636317
68Apathy (HP:0000741)2.23318417
69Diminished motivation (HP:0000745)2.20655074
70Reticulocytopenia (HP:0001896)2.19787229
71Stomach cancer (HP:0012126)2.19558742
72Abnormality of transition element cation homeostasis (HP:0011030)2.18625925
73Interstitial pulmonary disease (HP:0006530)2.17223280
74Recurrent fungal infections (HP:0002841)2.16686254
75Abnormality of the vasculature of the conjunctiva (HP:0008054)2.16556642
76Vasculitis (HP:0002633)2.15017816
77Distal lower limb muscle weakness (HP:0009053)2.14020564
78Abnormality of the intervertebral disk (HP:0005108)2.13233266
79Systemic lupus erythematosus (HP:0002725)2.12176622
80Increased CSF protein (HP:0002922)2.11813006
81Congenital ichthyosiform erythroderma (HP:0007431)2.11294299
82Cellulitis (HP:0100658)2.08720646
83Cupped ribs (HP:0000887)2.05894747
84Congenital, generalized hypertrichosis (HP:0004540)2.04017621
85Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.03468114
86Abnormality of lateral ventricle (HP:0030047)2.03306435
87Anhidrosis (HP:0000970)2.02740027
88Cardiomegaly (HP:0001640)2.02696831
89Polyneuropathy (HP:0001271)2.01463479
90Peritonitis (HP:0002586)2.00416052
91Leukocytosis (HP:0001974)2.00227905
92Vacuolated lymphocytes (HP:0001922)2.00092181
93Hepatosplenomegaly (HP:0001433)1.99434984
94Nasal polyposis (HP:0100582)1.98028109
95Impaired platelet aggregation (HP:0003540)1.97243424
96Abnormal platelet function (HP:0011869)1.97243424
97Alopecia of scalp (HP:0002293)1.95336976
98Fatigue (HP:0012378)1.94895758
99Aortic dissection (HP:0002647)1.94886981
100Inappropriate behavior (HP:0000719)1.94532810
101Keratoconjunctivitis sicca (HP:0001097)1.94287112
102Abnormality of the distal phalanges of the toes (HP:0010182)1.94107029
103Pulmonary infiltrates (HP:0002113)1.93713813
104Tetraparesis (HP:0002273)1.93368167
105Increased IgE level (HP:0003212)1.93124824
106Abnormal trabecular bone morphology (HP:0100671)1.92800853
107Purpura (HP:0000979)1.90876208
108Basal ganglia calcification (HP:0002135)1.90520833
109Albinism (HP:0001022)1.89344769
110Abnormal tarsal ossification (HP:0008369)1.88748615
111Recurrent skin infections (HP:0001581)1.87360304
112Milia (HP:0001056)1.85809522
113Onycholysis (HP:0001806)1.84796759
114Aortic aneurysm (HP:0004942)1.84708670
115Eosinophilia (HP:0001880)1.84631859
116Breast hypoplasia (HP:0003187)1.84319787
117Autoimmune hemolytic anemia (HP:0001890)1.83102167
118Neuronal loss in central nervous system (HP:0002529)1.82512100
119Segmental peripheral demyelination/remyelination (HP:0003481)1.82354994
120Plantar hyperkeratosis (HP:0007556)1.81750987
121Hypoproteinemia (HP:0003075)1.81623439
122Recurrent viral infections (HP:0004429)1.81401812
123Bone cyst (HP:0012062)1.81327378
124Abnormality of cells of the erythroid lineage (HP:0012130)1.80938499
125Hypergammaglobulinemia (HP:0010702)1.80439417
126Atrophic scars (HP:0001075)1.79700243
127Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.79580892
128Abnormal protein N-linked glycosylation (HP:0012347)1.79580892
129Abnormal protein glycosylation (HP:0012346)1.79580892
130Abnormal glycosylation (HP:0012345)1.79580892
131Skin ulcer (HP:0200042)1.78839871
132Short nail (HP:0001799)1.78133248
133Increased connective tissue (HP:0009025)1.77645686
134Dementia (HP:0000726)1.77387756
135Keratoconjunctivitis (HP:0001096)1.77202179
136Periodontitis (HP:0000704)1.76817713
137Fragile nails (HP:0001808)1.75318009
138Alveolar cell carcinoma (HP:0006519)1.74135786
139Poor head control (HP:0002421)1.70948159
140Micronodular cirrhosis (HP:0001413)1.70728408
141Obstructive lung disease (HP:0006536)1.68859061
142Chronic obstructive pulmonary disease (HP:0006510)1.68859061
143Asymmetric septal hypertrophy (HP:0001670)1.68812930
144Hemoptysis (HP:0002105)1.68764691
145J-shaped sella turcica (HP:0002680)1.66643339
146Recurrent gram-negative bacterial infections (HP:0005420)1.66639067
147Tubular atrophy (HP:0000092)1.66493946
148Recurrent pneumonia (HP:0006532)1.66407897
149Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.66031754
150Reduced subcutaneous adipose tissue (HP:0003758)1.65982092
151Hypertensive crisis (HP:0100735)1.65788204
152Retinal atrophy (HP:0001105)1.65666485
153Abnormal foot bone ossification (HP:0010675)1.64899957
154Gangrene (HP:0100758)1.64868406
155Abnormal number of erythroid precursors (HP:0012131)1.64141300
156Esophageal varix (HP:0002040)1.63612209
157Rough bone trabeculation (HP:0100670)1.63221701
158Abnormality of the pericardium (HP:0001697)1.62830633
159Abnormality of eosinophils (HP:0001879)1.62016768
160Entropion (HP:0000621)1.61668507
161Joint stiffness (HP:0001387)1.59801031
162Personality changes (HP:0000751)1.58388958
163Upper limb muscle weakness (HP:0003484)1.57857398

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIM23.43332367
2MAP3K142.96787217
3IRAK32.78534097
4CDK122.69470154
5MAP3K32.57211091
6NME22.46403478
7TYK22.43452158
8MAP3K122.24640650
9IKBKB2.17519261
10TBK12.17275142
11KDR1.92544964
12TGFBR21.92536787
13ADRBK21.89933740
14MAP4K11.89446247
15IKBKE1.86374390
16STK101.83592317
17MAP2K21.80584826
18ERN11.75842209
19ZAK1.73761107
20MAP2K31.72502598
21JAK31.71327950
22PIM11.70606604
23TIE11.68776021
24RPS6KA41.60523337
25EPHA21.59470929
26PBK1.54541717
27TEC1.54504209
28MAP3K111.51323656
29DDR21.46089811
30ZAP701.45790475
31CHUK1.37533665
32NLK1.36771340
33TXK1.34857056
34LIMK11.31979586
35IRAK41.30678193
36BRD41.24581161
37VRK11.19475755
38STK41.18978490
39TAOK11.18304646
40CDK91.16220680
41PRPF4B1.15270886
42TAOK31.14185691
43TESK11.11179548
44MATK1.11003032
45KIT1.10302055
46STK241.09261498
47MST41.09212537
48MARK31.08284554
49IRAK11.03927960
50EPHB11.03076990
51BCKDK1.02745983
52BLK1.01097059
53BTK0.99414631
54EPHA30.99122289
55CDK80.98776516
56PRKG20.98221819
57STK160.97693546
58JAK10.97286848
59ITK0.96541627
60MAP3K10.95558143
61MAPK150.95191205
62PAK40.94961518
63TESK20.94553621
64DYRK30.94521739
65ACVR1B0.90385434
66ARAF0.89849477
67TLK10.88925874
68CAMKK20.88036666
69CDK60.87316979
70ABL20.87274133
71HIPK20.84981345
72MAPKAPK20.84754465
73RPS6KB20.84438412
74TGFBR10.82252444
75RPS6KA50.80872077
76TAOK20.80590347
77MOS0.79582572
78NEK90.78161743
79MYLK0.77841735
80HCK0.77266498
81LATS20.73598179
82EIF2AK20.72824784
83TRPM70.71425796
84CSK0.71180865
85SIK30.68024448
86BMPR20.67977824
87STK30.67502289
88RPS6KA60.66020099
89MAP3K50.64752123
90PRKD20.64574521
91MST1R0.64169990
92GSK3A0.64019981
93EIF2AK30.63728726
94FGR0.62593212
95LRRK20.62522029
96RIPK10.59918631
97EPHB20.58822312
98PDK20.58422875
99MAP2K60.57863882
100FGFR40.57550984
101MAPKAPK30.57028193
102MELK0.55879201
103CDC42BPA0.53593826
104LCK0.52636430
105NEK20.51911955
106IRAK20.51011441
107GRK70.50989183
108RPS6KC10.50564759
109RPS6KL10.50564759
110STK38L0.50078378
111CDK70.49272869
112ADRBK10.48861861
113MAP3K80.48562221
114AURKB0.45182971
115ABL10.44416714
116WEE10.43928226
117BRSK20.42927792
118DAPK30.42782323
119JAK20.40331875
120PRKCI0.39453253
121GRK10.39365051
122MAPK70.38851265
123CDK40.38848470
124LYN0.38334310
125PIK3CA0.36999899
126MAP3K100.36011002
127PAK10.34317558
128CSF1R0.33268938
129DMPK0.32485793
130MAPK40.31241678
131PKN10.30342770
132PRKCD0.30287461
133ERBB40.27518514
134ILK0.27413310
135BUB10.26782827
136CAMK2G0.26554447
137RPS6KA10.25171570
138BMX0.24367182
139INSR0.17316116

Predicted pathways (KEGG)

RankGene SetZ-score
1Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.68650324
2Intestinal immune network for IgA production_Homo sapiens_hsa046722.63456343
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.53495492
4Leishmaniasis_Homo sapiens_hsa051402.51185009
5Malaria_Homo sapiens_hsa051442.13026242
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.02027052
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.01462301
8Herpes simplex infection_Homo sapiens_hsa051681.89635475
9Ribosome_Homo sapiens_hsa030101.89557657
10RNA polymerase_Homo sapiens_hsa030201.87246514
11Measles_Homo sapiens_hsa051621.86471160
12TNF signaling pathway_Homo sapiens_hsa046681.85937236
13Legionellosis_Homo sapiens_hsa051341.85468177
14Graft-versus-host disease_Homo sapiens_hsa053321.83629218
15Pertussis_Homo sapiens_hsa051331.79293697
16Osteoclast differentiation_Homo sapiens_hsa043801.76339852
17Apoptosis_Homo sapiens_hsa042101.74629997
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.73340921
19Collecting duct acid secretion_Homo sapiens_hsa049661.65794465
20Toxoplasmosis_Homo sapiens_hsa051451.62577369
21Sulfur metabolism_Homo sapiens_hsa009201.62418968
22NOD-like receptor signaling pathway_Homo sapiens_hsa046211.61343005
23p53 signaling pathway_Homo sapiens_hsa041151.56613419
24Influenza A_Homo sapiens_hsa051641.55741673
25Allograft rejection_Homo sapiens_hsa053301.52170153
26Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.46909841
27Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.42773935
28Antigen processing and presentation_Homo sapiens_hsa046121.38356766
29Sulfur relay system_Homo sapiens_hsa041221.38272438
30Hematopoietic cell lineage_Homo sapiens_hsa046401.37226573
31Rheumatoid arthritis_Homo sapiens_hsa053231.34287719
32Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.33692938
33Type I diabetes mellitus_Homo sapiens_hsa049401.33344454
34Hepatitis B_Homo sapiens_hsa051611.32617503
35Primary immunodeficiency_Homo sapiens_hsa053401.30918464
36Jak-STAT signaling pathway_Homo sapiens_hsa046301.30561122
37Staphylococcus aureus infection_Homo sapiens_hsa051501.25846174
38Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.24130598
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.22375402
40AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21024970
41Vibrio cholerae infection_Homo sapiens_hsa051101.17012878
42Shigellosis_Homo sapiens_hsa051311.15865531
43Prion diseases_Homo sapiens_hsa050201.13955104
44Salmonella infection_Homo sapiens_hsa051321.12846976
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11381920
46Small cell lung cancer_Homo sapiens_hsa052221.09388876
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.08835109
48Tuberculosis_Homo sapiens_hsa051521.07921719
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.07709142
50B cell receptor signaling pathway_Homo sapiens_hsa046621.05017774
51Hepatitis C_Homo sapiens_hsa051601.03901512
52Oxidative phosphorylation_Homo sapiens_hsa001901.03427704
53Folate biosynthesis_Homo sapiens_hsa007901.02854110
54Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02397876
55Pyrimidine metabolism_Homo sapiens_hsa002401.02146948
56Autoimmune thyroid disease_Homo sapiens_hsa053201.02000307
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.98976382
58HTLV-I infection_Homo sapiens_hsa051660.98024812
59Other glycan degradation_Homo sapiens_hsa005110.97629224
60Epstein-Barr virus infection_Homo sapiens_hsa051690.97378072
61Bladder cancer_Homo sapiens_hsa052190.93028272
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.92589972
63Proteasome_Homo sapiens_hsa030500.91778385
64Arachidonic acid metabolism_Homo sapiens_hsa005900.91100092
65Asthma_Homo sapiens_hsa053100.90795536
66African trypanosomiasis_Homo sapiens_hsa051430.88290240
67Viral carcinogenesis_Homo sapiens_hsa052030.85506095
68Chronic myeloid leukemia_Homo sapiens_hsa052200.85469933
69ECM-receptor interaction_Homo sapiens_hsa045120.83447471
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.82460431
71Cell cycle_Homo sapiens_hsa041100.82276481
72T cell receptor signaling pathway_Homo sapiens_hsa046600.82226672
73Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79526679
74Viral myocarditis_Homo sapiens_hsa054160.78804725
75Basal transcription factors_Homo sapiens_hsa030220.76567139
76Amoebiasis_Homo sapiens_hsa051460.74838151
77Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74033491
78Regulation of autophagy_Homo sapiens_hsa041400.72497607
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.71549924
80TGF-beta signaling pathway_Homo sapiens_hsa043500.69394907
81Acute myeloid leukemia_Homo sapiens_hsa052210.68709426
82Systemic lupus erythematosus_Homo sapiens_hsa053220.68684461
83HIF-1 signaling pathway_Homo sapiens_hsa040660.68586969
84Chemokine signaling pathway_Homo sapiens_hsa040620.68319734
85Glycosaminoglycan degradation_Homo sapiens_hsa005310.68191751
86Complement and coagulation cascades_Homo sapiens_hsa046100.67964407
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64339925
88Phagosome_Homo sapiens_hsa041450.63622897
89Prolactin signaling pathway_Homo sapiens_hsa049170.62919832
90MicroRNAs in cancer_Homo sapiens_hsa052060.61622254
91Base excision repair_Homo sapiens_hsa034100.61526567
92Lysosome_Homo sapiens_hsa041420.58991571
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.58739242
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.58532773
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54759080
96Mineral absorption_Homo sapiens_hsa049780.53970415
97Focal adhesion_Homo sapiens_hsa045100.52262521
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51972248
99Platelet activation_Homo sapiens_hsa046110.51317448
100FoxO signaling pathway_Homo sapiens_hsa040680.50893456
101Glutathione metabolism_Homo sapiens_hsa004800.50565182
102Proteoglycans in cancer_Homo sapiens_hsa052050.49866180
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48516398
104Pancreatic cancer_Homo sapiens_hsa052120.48369512
105Sphingolipid metabolism_Homo sapiens_hsa006000.47847403
106Adherens junction_Homo sapiens_hsa045200.47537461
107Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.47386440
108Non-homologous end-joining_Homo sapiens_hsa034500.47182457
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46249490
110DNA replication_Homo sapiens_hsa030300.45961211
111Galactose metabolism_Homo sapiens_hsa000520.43909044
112Primary bile acid biosynthesis_Homo sapiens_hsa001200.43008969
113RNA degradation_Homo sapiens_hsa030180.42982450
114Pathways in cancer_Homo sapiens_hsa052000.41387604
115Fructose and mannose metabolism_Homo sapiens_hsa000510.40137823
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.39904026
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39687366
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.39147995
119Parkinsons disease_Homo sapiens_hsa050120.37902214
120Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37473716
121Prostate cancer_Homo sapiens_hsa052150.37329027
122Tryptophan metabolism_Homo sapiens_hsa003800.35680114
123Thyroid cancer_Homo sapiens_hsa052160.34416920
124Notch signaling pathway_Homo sapiens_hsa043300.33634873
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.33480365
126MAPK signaling pathway_Homo sapiens_hsa040100.30141116
127Endocytosis_Homo sapiens_hsa041440.28655879
128Alzheimers disease_Homo sapiens_hsa050100.19912803
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.18055707
130Huntingtons disease_Homo sapiens_hsa050160.17382415
131Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.16719480
132Protein export_Homo sapiens_hsa030600.16158726

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