SERTAD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to muramyl dipeptide (GO:0032495)4.10882277
2regulation of interleukin-12 biosynthetic process (GO:0045075)3.57651053
3positive regulation of p38MAPK cascade (GO:1900745)3.47071923
4neutrophil activation involved in immune response (GO:0002283)3.46485034
5positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.38553236
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.34945857
7cellular extravasation (GO:0045123)3.31404862
8detection of other organism (GO:0098543)3.21102064
9pinocytosis (GO:0006907)3.21056913
10hypotonic response (GO:0006971)3.12239014
11detection of bacterium (GO:0016045)3.11542462
12positive regulation of interferon-alpha production (GO:0032727)3.10441408
13positive regulation of B cell differentiation (GO:0045579)3.09634822
14germinal center formation (GO:0002467)3.09591623
15membrane raft organization (GO:0031579)3.08328996
16regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.08185234
17regulation of chromatin binding (GO:0035561)3.04135181
18positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.04116140
19wound healing, spreading of epidermal cells (GO:0035313)3.02519751
20hepatocyte apoptotic process (GO:0097284)2.99864431
21macrophage activation involved in immune response (GO:0002281)2.98986482
22positive regulation by symbiont of host defense response (GO:0052509)2.98816376
23modulation by symbiont of host defense response (GO:0052031)2.98816376
24modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.98816376
25modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.98816376
26positive regulation by organism of defense response of other organism involved in symbiotic interact2.98816376
27modulation by symbiont of host immune response (GO:0052553)2.98816376
28germ cell migration (GO:0008354)2.96844728
29negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.95926889
30regulation of integrin activation (GO:0033623)2.95050655
31regulation of interferon-alpha production (GO:0032647)2.91282704
32regulation of vitamin D biosynthetic process (GO:0060556)2.90326744
33erythrocyte maturation (GO:0043249)2.87589912
34definitive hemopoiesis (GO:0060216)2.84587174
35response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.83712892
36response to host (GO:0075136)2.83712892
37response to host defenses (GO:0052200)2.83712892
38negative regulation of interleukin-8 production (GO:0032717)2.82306534
39tolerance induction (GO:0002507)2.81098602
40B cell receptor signaling pathway (GO:0050853)2.79452521
41skin morphogenesis (GO:0043589)2.76997048
42positive regulation of gamma-delta T cell activation (GO:0046645)2.76931957
43regulation of p38MAPK cascade (GO:1900744)2.76792290
44negative regulation of interleukin-12 production (GO:0032695)2.76494524
45regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.75192938
46negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.74777665
47response to interferon-alpha (GO:0035455)2.74009450
48cellular response to fluid shear stress (GO:0071498)2.72819811
49regulation of leukocyte degranulation (GO:0043300)2.70678040
50hemidesmosome assembly (GO:0031581)2.70585315
51regulation of mast cell degranulation (GO:0043304)2.69794503
52mRNA transcription (GO:0009299)2.69217155
53positive thymic T cell selection (GO:0045059)2.68558911
54detection of external biotic stimulus (GO:0098581)2.63067776
55regulation of B cell receptor signaling pathway (GO:0050855)2.62027291
56apoptotic cell clearance (GO:0043277)2.60605437
57positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.60495280
58regulation of RIG-I signaling pathway (GO:0039535)2.60380577
59regulation of T-helper 2 cell differentiation (GO:0045628)2.59779716
60B cell homeostasis (GO:0001782)2.59460068
61natural killer cell differentiation (GO:0001779)2.59100603
62positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.56550064
63negative regulation of interleukin-6 production (GO:0032715)2.56232283
64negative regulation of toll-like receptor signaling pathway (GO:0034122)2.55112707
65regulation of interferon-beta biosynthetic process (GO:0045357)2.55088258
66antigen processing and presentation of endogenous antigen (GO:0019883)2.54858264
67response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.52414946
68response to host immune response (GO:0052572)2.52414946
69regulation of vitamin metabolic process (GO:0030656)2.51446728
70response to laminar fluid shear stress (GO:0034616)2.51327363
71fibroblast migration (GO:0010761)2.50960442
72immunoglobulin mediated immune response (GO:0016064)2.50349086
73cell adhesion mediated by integrin (GO:0033627)2.49167846
74mannose metabolic process (GO:0006013)2.48373282
75granulocyte activation (GO:0036230)2.46078155
76regulation of B cell differentiation (GO:0045577)2.45805585
77cellular response to exogenous dsRNA (GO:0071360)2.45770829
78regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.45486840
79regulation of T-helper 1 cell differentiation (GO:0045625)2.44794325
80negative regulation of erythrocyte differentiation (GO:0045647)2.44101468
81detection of molecule of bacterial origin (GO:0032490)2.43919994
82positive regulation of natural killer cell differentiation (GO:0032825)2.43805898
83detection of biotic stimulus (GO:0009595)2.43676266
84regulation of monocyte differentiation (GO:0045655)2.43499278
85regulation of myeloid leukocyte mediated immunity (GO:0002886)2.43433104
86regulation of mast cell activation involved in immune response (GO:0033006)2.43334224
87regulation of necroptotic process (GO:0060544)2.42785780
88cellular response to thyroid hormone stimulus (GO:0097067)2.42626587
89myeloid cell activation involved in immune response (GO:0002275)2.42528898
90neutrophil mediated immunity (GO:0002446)2.42041725
91CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.41701787
92negative regulation of fatty acid transport (GO:2000192)2.41291340
93monocyte chemotaxis (GO:0002548)2.40604194
94response to protozoan (GO:0001562)2.40485836
95antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.39586912
96stress fiber assembly (GO:0043149)2.39240532
97neutrophil activation (GO:0042119)2.38654508
98regulation of macrophage cytokine production (GO:0010935)2.38239665
99leukocyte aggregation (GO:0070486)2.37089044
100protein localization to endosome (GO:0036010)2.37060562
101macrophage chemotaxis (GO:0048246)2.36559587
102positive regulation of granulocyte differentiation (GO:0030854)2.35563998
103megakaryocyte development (GO:0035855)2.35128124
104positive regulation of lipid storage (GO:0010884)2.34949879
1053-UTR-mediated mRNA stabilization (GO:0070935)2.34581200
106antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.33617153
107positive regulation of extracellular matrix organization (GO:1903055)2.33033271
108negative regulation of granulocyte differentiation (GO:0030853)2.33005208
109positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.32758425
110response to fluid shear stress (GO:0034405)2.32465794
111cellular response to virus (GO:0098586)2.32447241
112positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.31213824
113negative regulation of cell killing (GO:0031342)2.31191842
114negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.31191842
115embryonic process involved in female pregnancy (GO:0060136)2.31059956
116endodermal cell differentiation (GO:0035987)2.30026459
117defense response to protozoan (GO:0042832)2.27827389
118negative regulation of necroptotic process (GO:0060546)2.27199991
119negative regulation of cytokine production involved in immune response (GO:0002719)2.25422892
120cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.25278456
121positive regulation of histone deacetylation (GO:0031065)2.25174170
122negative regulation of interleukin-17 production (GO:0032700)2.24677108
123regulation of toll-like receptor signaling pathway (GO:0034121)2.24393411
124response to peptidoglycan (GO:0032494)2.24176713
125response to type I interferon (GO:0034340)2.23845171
126regulation of interleukin-6 production (GO:0032675)2.23536761
127response to exogenous dsRNA (GO:0043330)2.23019699
128positive regulation of erythrocyte differentiation (GO:0045648)2.22957095
129interferon-gamma secretion (GO:0072643)2.22521154
130modulation by symbiont of host cellular process (GO:0044068)2.22092364
131dosage compensation (GO:0007549)2.21807534
132membrane protein intracellular domain proteolysis (GO:0031293)2.20342695
133regulation of gamma-delta T cell activation (GO:0046643)2.20311177
134fusion of sperm to egg plasma membrane (GO:0007342)2.20284125
135regulation of heterotypic cell-cell adhesion (GO:0034114)2.19230672
136positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.17962447
137positive regulation of chemokine biosynthetic process (GO:0045080)2.17939201
138positive regulation of myotube differentiation (GO:0010831)2.17323928
139regulation of gamma-delta T cell differentiation (GO:0045586)2.16718389
140substrate adhesion-dependent cell spreading (GO:0034446)2.15783688
141genitalia morphogenesis (GO:0035112)2.15651174
142regulation of mononuclear cell migration (GO:0071675)2.15364452
143epithelial cell-cell adhesion (GO:0090136)2.14983328
144wound healing, spreading of cells (GO:0044319)2.14706351
145regulation of erythrocyte differentiation (GO:0045646)2.13918415
146NIK/NF-kappaB signaling (GO:0038061)2.13910539
147regulation of podosome assembly (GO:0071801)2.13564421
148positive regulation of endothelial cell apoptotic process (GO:2000353)2.13038741
149cellular response to type I interferon (GO:0071357)2.12852704
150type I interferon signaling pathway (GO:0060337)2.12852704
151positive regulation of interferon-beta production (GO:0032728)2.12764203
152regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.11397977
153regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.10177355
154negative regulation of bone mineralization (GO:0030502)2.10161066
155establishment of endothelial barrier (GO:0061028)2.10031716
156negative regulation of stress fiber assembly (GO:0051497)2.09511536
157pathway-restricted SMAD protein phosphorylation (GO:0060389)2.07740189
158hippo signaling (GO:0035329)2.06023327
159cell-substrate junction assembly (GO:0007044)2.05720977
160low-density lipoprotein particle clearance (GO:0034383)2.05369824
161ectoderm development (GO:0007398)2.05286152
162G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.04116212
163acrosome reaction (GO:0007340)2.03887358
164positive T cell selection (GO:0043368)2.03644446
165lipopolysaccharide-mediated signaling pathway (GO:0031663)2.03639696
166desmosome organization (GO:0002934)2.03517227
167positive regulation of triglyceride biosynthetic process (GO:0010867)2.03151551
168bone remodeling (GO:0046849)2.02961606
169basement membrane organization (GO:0071711)2.00846811
170cyclooxygenase pathway (GO:0019371)2.00190176
171regulation of type I interferon-mediated signaling pathway (GO:0060338)2.00001947
172vascular endothelial growth factor signaling pathway (GO:0038084)1.99715007

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.78737864
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.73088808
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.30551620
4IRF8_22096565_ChIP-ChIP_GC-B_Human2.99219833
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.73833289
6RARG_19884340_ChIP-ChIP_MEFs_Mouse2.71852021
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.70233139
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.69994841
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.47696526
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.24761021
11NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.20251271
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.19541049
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.19066393
14* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.15505750
15* TCF7_22412390_ChIP-Seq_EML_Mouse2.14457624
16IRF8_27001747_Chip-Seq_BMDM_Mouse2.14157675
17SCL_19346495_ChIP-Seq_HPC-7_Human2.02276303
18TRIM28_21343339_ChIP-Seq_HEK293_Human2.02073938
19IRF8_21731497_ChIP-ChIP_J774_Mouse1.99556678
20VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.96741681
21Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.95609971
22BRD4_27068464_Chip-Seq_AML-cells_Mouse1.93244088
23* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.91233321
24MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.91208220
25VDR_24763502_ChIP-Seq_THP-1_Human1.90533377
26MAF_26560356_Chip-Seq_TH1_Human1.87877747
27ELK3_25401928_ChIP-Seq_HUVEC_Human1.87207826
28* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.84710691
29MYC_22102868_ChIP-Seq_BL_Human1.80966696
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.80122309
31VDR_21846776_ChIP-Seq_THP-1_Human1.76777266
32CLOCK_20551151_ChIP-Seq_293T_Human1.73503800
33SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.69499278
34* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.68283135
35CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.68199526
36IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.67031064
37KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66028661
38FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.63327849
39ZNF263_19887448_ChIP-Seq_K562_Human1.61224762
40TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60397547
41KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56730737
42IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.54707043
43FOXM1_23109430_ChIP-Seq_U2OS_Human1.53020203
44STAT4_19710469_ChIP-ChIP_TH1__Mouse1.52526765
45KDM2B_26808549_Chip-Seq_JURKAT_Human1.50944890
46MYB_26560356_Chip-Seq_TH2_Human1.50005891
47NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.48978403
48* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.48595720
49* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.48066551
50* RUNX1_22412390_ChIP-Seq_EML_Mouse1.46326647
51KDM2B_26808549_Chip-Seq_DND41_Human1.44975900
52* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.43940194
53* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.43940194
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.43819898
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.41975864
56* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.41323556
57RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40738882
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.39577869
59GATA2_21666600_ChIP-Seq_HMVEC_Human1.36901470
60* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.36578097
61FOXO3_23340844_ChIP-Seq_DLD1_Human1.36115621
62MAF_26560356_Chip-Seq_TH2_Human1.32987963
63* MYB_26560356_Chip-Seq_TH1_Human1.31849295
64ATF3_27146783_Chip-Seq_COLON_Human1.31719557
65KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.31562890
66CJUN_26792858_Chip-Seq_BT549_Human1.31205432
67RUNX_20019798_ChIP-Seq_JUKART_Human1.30974740
68* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.30238434
69VDR_24787735_ChIP-Seq_THP-1_Human1.29242395
70SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.27396603
71PU_27001747_Chip-Seq_BMDM_Mouse1.25622522
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.24335152
73* UTX_26944678_Chip-Seq_JUKART_Human1.24069783
74* GATA2_19941826_ChIP-Seq_K562_Human1.21924346
75GATA1_19941826_ChIP-Seq_K562_Human1.20028248
76NCOR1_26117541_ChIP-Seq_K562_Human1.19743145
77* BRD4_25478319_ChIP-Seq_HGPS_Human1.19111810
78SOX9_24532713_ChIP-Seq_HFSC_Mouse1.17827662
79ESR2_21235772_ChIP-Seq_MCF-7_Human1.17082121
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.16855247
81TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16689816
82GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16269927
83KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15515690
84* KDM2B_26808549_Chip-Seq_K562_Human1.14495225
85MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.13457990
86* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.12561883
87UBF1/2_26484160_Chip-Seq_HMECs_Human1.12127499
88* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.11755186
89* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11008419
90CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.09673948
91* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.09664000
92RACK7_27058665_Chip-Seq_MCF-7_Human1.09615374
93ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.09090059
94GATA1_19941827_ChIP-Seq_MEL_Mouse1.08311776
95* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.06751198
96CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06214544
97PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05272184
98THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04343592
99LXR_22292898_ChIP-Seq_THP-1_Human1.04331359
100PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02930468
101ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.01969800
102GATA1_22025678_ChIP-Seq_K562_Human1.01936600
103VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01467966
104PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.01043860
105GATA4_25053715_ChIP-Seq_YYC3_Human0.99464566
106SPI1_23547873_ChIP-Seq_NB4_Human0.99253361
107WT1_19549856_ChIP-ChIP_CCG9911_Human0.99225146
108ESR1_21235772_ChIP-Seq_MCF-7_Human0.99048100
109STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.98855274
110CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.98789406
111SPI1_23127762_ChIP-Seq_K562_Human0.98772887
112FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.98206040
113* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98024559
114* RUNX1_27514584_Chip-Seq_MCF-7_Human0.97986184
115* TBX20_22080862_ChIP-Seq_HEART_Mouse0.97680412
116* TBX20_22328084_ChIP-Seq_HEART_Mouse0.97680412
117SMAD_19615063_ChIP-ChIP_OVARY_Human0.97659987
118GATA3_27048872_Chip-Seq_THYMUS_Human0.97363809
119JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97274293
120SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94649640
121GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93539055

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.12357767
2MP0003303_peritoneal_inflammation2.83413978
3MP0003436_decreased_susceptibility_to2.47943976
4MP0003300_gastrointestinal_ulcer2.31333130
5MP0008438_abnormal_cutaneous_collagen2.29206687
6MP0003191_abnormal_cellular_cholesterol2.26713210
7MP0005275_abnormal_skin_tensile2.07714897
8MP0010352_gastrointestinal_tract_polyps1.94260924
9MP0005058_abnormal_lysosome_morphology1.91441799
10MP0009278_abnormal_bone_marrow1.89128868
11MP0003566_abnormal_cell_adhesion1.87158447
12MP0002877_abnormal_melanocyte_morpholog1.82322336
13MP0003950_abnormal_plasma_membrane1.72885318
14MP0005409_darkened_coat_color1.71820096
15MP0003279_aneurysm1.71271779
16MP0005023_abnormal_wound_healing1.69481871
17MP0000685_abnormal_immune_system1.66646044
18MP0002254_reproductive_system_inflammat1.64432761
19MP0005257_abnormal_intraocular_pressure1.61241973
20MP0003172_abnormal_lysosome_physiology1.60646521
21MP0005451_abnormal_body_composition1.59127920
22MP0003091_abnormal_cell_migration1.58534395
23MP0005397_hematopoietic_system_phenotyp1.51471998
24MP0001545_abnormal_hematopoietic_system1.51471998
25MP0005076_abnormal_cell_differentiation1.48291146
26MP0003828_pulmonary_edema1.47509483
27MP0003656_abnormal_erythrocyte_physiolo1.45888966
28MP0004947_skin_inflammation1.44678227
29MP0002933_joint_inflammation1.41401214
30MP0009840_abnormal_foam_cell1.40775424
31MP0002405_respiratory_system_inflammati1.39594305
32MP0004808_abnormal_hematopoietic_stem1.39177011
33MP0003763_abnormal_thymus_physiology1.38349192
34MP0005464_abnormal_platelet_physiology1.38244736
35MP0005000_abnormal_immune_tolerance1.37659761
36MP0001853_heart_inflammation1.36793086
37MP0003453_abnormal_keratinocyte_physiol1.36717666
38MP0006082_CNS_inflammation1.35400507
39MP0005164_abnormal_response_to1.35334280
40MP0001533_abnormal_skeleton_physiology1.33674020
41MP0001835_abnormal_antigen_presentation1.32841112
42MP0009785_altered_susceptibility_to1.29985686
43MP0002060_abnormal_skin_morphology1.28811388
44MP0000767_abnormal_smooth_muscle1.26368028
45MP0003724_increased_susceptibility_to1.25680848
46MP0002452_abnormal_antigen_presenting1.24323083
47MP0003045_fibrosis1.23914243
48MP0003448_altered_tumor_morphology1.23550997
49MP0002419_abnormal_innate_immunity1.21738892
50MP0005623_abnormal_meninges_morphology1.21169713
51MP0000343_altered_response_to1.20710286
52MP0005025_abnormal_response_to1.19812480
53MP0000733_abnormal_muscle_development1.18201563
54MP0009333_abnormal_splenocyte_physiolog1.17289020
55MP0002148_abnormal_hypersensitivity_rea1.16265997
56MP0004185_abnormal_adipocyte_glucose1.14182948
57MP0008961_abnormal_basal_metabolism1.13968695
58MP0005410_abnormal_fertilization1.13851250
59MP0002998_abnormal_bone_remodeling1.12114983
60MP0002723_abnormal_immune_serum1.11946861
61MP0000371_diluted_coat_color1.10355206
62MP0002168_other_aberrant_phenotype1.10246877
63MP0009053_abnormal_anal_canal1.09000738
64MP0004883_abnormal_blood_vessel1.08790249
65MP0010155_abnormal_intestine_physiology1.08350837
66MP0000490_abnormal_crypts_of1.08319596
67MP0005390_skeleton_phenotype1.08103453
68MP0003252_abnormal_bile_duct1.06987127
69MP0002398_abnormal_bone_marrow1.06050582
70MP0001800_abnormal_humoral_immune1.05760741
71MP0005671_abnormal_response_to1.04193945
72MP0002420_abnormal_adaptive_immunity1.04005665
73MP0001819_abnormal_immune_cell1.03526484
74MP0003567_abnormal_fetal_cardiomyocyte1.02315030
75MP0000689_abnormal_spleen_morphology1.01854621
76MP0000858_altered_metastatic_potential1.01753612
77MP0002006_tumorigenesis1.00733235
78MP0001849_ear_inflammation1.00115748
79MP0004510_myositis0.99122322
80MP0005501_abnormal_skin_physiology0.97424059
81MP0008004_abnormal_stomach_pH0.94537265
82MP0003941_abnormal_skin_development0.93818366
83MP0001851_eye_inflammation0.92623769
84MP0000249_abnormal_blood_vessel0.92610148
85MP0008469_abnormal_protein_level0.92592503
86MP0002282_abnormal_trachea_morphology0.92345383
87MP0002722_abnormal_immune_system0.91943855
88MP0009115_abnormal_fat_cell0.91541541
89MP0001958_emphysema0.90700442
90MP0005666_abnormal_adipose_tissue0.89695433
91MP0003795_abnormal_bone_structure0.87270306
92MP0005387_immune_system_phenotype0.86736352
93MP0001790_abnormal_immune_system0.86736352
94MP0008007_abnormal_cellular_replicative0.86475940
95MP0010234_abnormal_vibrissa_follicle0.86200693
96MP0005621_abnormal_cell_physiology0.85772739
97MP0001243_abnormal_dermal_layer0.85371366
98MP0000716_abnormal_immune_system0.85092252
99MP0002166_altered_tumor_susceptibility0.84705602
100MP0009764_decreased_sensitivity_to0.84172675
101MP0008789_abnormal_olfactory_epithelium0.84094512
102MP0010630_abnormal_cardiac_muscle0.84031506
103MP0002009_preneoplasia0.83839086
104MP0004272_abnormal_basement_membrane0.83217950
105MP0004264_abnormal_extraembryonic_tissu0.83043804
106MP0002396_abnormal_hematopoietic_system0.82859112
107MP0005503_abnormal_tendon_morphology0.82018143
108MP0005508_abnormal_skeleton_morphology0.81689788
109MP0001845_abnormal_inflammatory_respons0.80521075
110MP0001216_abnormal_epidermal_layer0.79552746
111MP0009931_abnormal_skin_appearance0.79492011
112MP0002138_abnormal_hepatobiliary_system0.78688798
113MP0003075_altered_response_to0.78223198
114MP0002115_abnormal_skeleton_extremities0.76866099
115MP0002429_abnormal_blood_cell0.76548976
116MP0003385_abnormal_body_wall0.76169906
117MP0005174_abnormal_tail_pigmentation0.76026644
118MP0001873_stomach_inflammation0.75962423
119MP0010307_abnormal_tumor_latency0.75911821
120MP0005375_adipose_tissue_phenotype0.75563848
121MP0002098_abnormal_vibrissa_morphology0.75183512
122MP0009763_increased_sensitivity_to0.74931229
123MP0002796_impaired_skin_barrier0.74378382
124MP0000703_abnormal_thymus_morphology0.72866564
125MP0001915_intracranial_hemorrhage0.69585713
126MP0000015_abnormal_ear_pigmentation0.69570589
127MP0003221_abnormal_cardiomyocyte_apopto0.69371309

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)3.67607164
2Premature rupture of membranes (HP:0001788)3.32594562
3Increased connective tissue (HP:0009025)3.27711453
4Aortic aneurysm (HP:0004942)3.05538072
5Abnormality of macrophages (HP:0004311)3.01479430
6Spinal cord lesions (HP:0100561)2.95619374
7Syringomyelia (HP:0003396)2.95619374
8Atrophic scars (HP:0001075)2.92980319
9Vertebral compression fractures (HP:0002953)2.92791970
10Recurrent bacterial skin infections (HP:0005406)2.82359896
11Cerebral aneurysm (HP:0004944)2.81909253
12Aortic dissection (HP:0002647)2.76732587
13Pustule (HP:0200039)2.73519043
14Peritonitis (HP:0002586)2.73284023
15Prolonged bleeding time (HP:0003010)2.68507960
16Shallow orbits (HP:0000586)2.67555154
17Ankle contracture (HP:0006466)2.59195185
18Recurrent abscess formation (HP:0002722)2.58618510
19Osteolytic defects of the hand bones (HP:0009699)2.56249658
20Osteolytic defects of the phalanges of the hand (HP:0009771)2.56249658
21Mitral valve prolapse (HP:0001634)2.50181957
22Epistaxis (HP:0000421)2.43982330
23Autoimmune thrombocytopenia (HP:0001973)2.39183118
24Genu recurvatum (HP:0002816)2.38536501
25Cupped ribs (HP:0000887)2.38465059
26Myocardial infarction (HP:0001658)2.36732494
27Gingival bleeding (HP:0000225)2.34816217
28Absent frontal sinuses (HP:0002688)2.34696500
29Colitis (HP:0002583)2.33239347
30Right ventricular cardiomyopathy (HP:0011663)2.32204211
31Dilatation of the ascending aorta (HP:0005111)2.30856902
32Abnormality of the nasal mucosa (HP:0000433)2.29660774
33Vasculitis (HP:0002633)2.28667133
34Thrombocytosis (HP:0001894)2.25948941
35Fatigue (HP:0012378)2.25352319
36Meningitis (HP:0001287)2.24797708
37Spinal rigidity (HP:0003306)2.24504524
38Nasal polyposis (HP:0100582)2.23862207
39Cervical subluxation (HP:0003308)2.22429759
40Radial bowing (HP:0002986)2.20417435
41Pulmonary infiltrates (HP:0002113)2.20331123
42Dysostosis multiplex (HP:0000943)2.20140604
43Fragile skin (HP:0001030)2.20106765
44Camptodactyly of toe (HP:0001836)2.18199678
45Spontaneous hematomas (HP:0007420)2.16572039
46Disproportionate tall stature (HP:0001519)2.16198108
47Hypoplastic ischia (HP:0003175)2.14641411
48Agammaglobulinemia (HP:0004432)2.11627298
49Prostate neoplasm (HP:0100787)2.11540126
50Eczematoid dermatitis (HP:0000976)2.11120598
51Ulnar bowing (HP:0003031)2.11080557
52Abnormality of liposaccharide metabolism (HP:0010968)2.10227130
53Abnormality of glycosphingolipid metabolism (HP:0004343)2.10227130
54Abnormality of glycolipid metabolism (HP:0010969)2.10227130
55Epiphyseal dysplasia (HP:0002656)2.09012213
56Viral hepatitis (HP:0006562)2.08977091
57Polygenic inheritance (HP:0010982)2.08668028
58Recurrent skin infections (HP:0001581)2.07800601
59Poikilocytosis (HP:0004447)2.06757703
60Chronic mucocutaneous candidiasis (HP:0002728)2.04455793
61Recurrent cutaneous fungal infections (HP:0011370)2.04455793
62Abnormality of the fingertips (HP:0001211)1.99654045
63Flat acetabular roof (HP:0003180)1.97728609
64Alopecia of scalp (HP:0002293)1.97212228
65Recurrent fungal infections (HP:0002841)1.97141614
66Acute myeloid leukemia (HP:0004808)1.96962748
67Pelvic girdle muscle weakness (HP:0003749)1.95369324
68Abnormality of the acetabulum (HP:0003170)1.94982782
69Subacute progressive viral hepatitis (HP:0006572)1.94820138
70Myositis (HP:0100614)1.93344030
71Increased density of long bones (HP:0006392)1.92700840
72Wormian bones (HP:0002645)1.92347497
73Osteomyelitis (HP:0002754)1.91256952
74Abnormal platelet function (HP:0011869)1.91205296
75Impaired platelet aggregation (HP:0003540)1.91205296
76Urticaria (HP:0001025)1.90772055
77Increased mean platelet volume (HP:0011877)1.89923020
78Soft skin (HP:0000977)1.89199630
79Chronic obstructive pulmonary disease (HP:0006510)1.88501065
80Obstructive lung disease (HP:0006536)1.88501065
81Elbow flexion contracture (HP:0002987)1.88398400
82Recurrent viral infections (HP:0004429)1.88206279
83Abnormal platelet volume (HP:0011876)1.87665654
84Biconcave vertebral bodies (HP:0004586)1.87377092
85Hemorrhage of the eye (HP:0011885)1.87289433
86Long eyelashes (HP:0000527)1.85475143
87Milia (HP:0001056)1.85443271
88Autoimmune hemolytic anemia (HP:0001890)1.83625524
89Inflammation of the large intestine (HP:0002037)1.82752766
90Orchitis (HP:0100796)1.82677585
91Short nail (HP:0001799)1.82516169
92Bowed forearm bones (HP:0003956)1.82231877
93Bowing of the arm (HP:0006488)1.82231877
94Broad face (HP:0000283)1.81608468
95Vacuolated lymphocytes (HP:0001922)1.81521550
96Mitral regurgitation (HP:0001653)1.81356360
97Arterial thrombosis (HP:0004420)1.80878057
98Spondylolisthesis (HP:0003302)1.79998812
99Thin ribs (HP:0000883)1.79892423
100Chest pain (HP:0100749)1.79380823
101Gastrointestinal stroma tumor (HP:0100723)1.78822898
102Obstructive sleep apnea (HP:0002870)1.78721653
103Emphysema (HP:0002097)1.78003074
104Flexion contracture of toe (HP:0005830)1.77765215
105Joint contractures involving the joints of the feet (HP:0100492)1.77765215
106Gingivitis (HP:0000230)1.77589500
107Mediastinal lymphadenopathy (HP:0100721)1.77318984
108Recurrent gram-negative bacterial infections (HP:0005420)1.76979233
109Vascular tortuosity (HP:0004948)1.75795914
110Xerostomia (HP:0000217)1.75297188
111Hypergammaglobulinemia (HP:0010702)1.75101417
112Abnormality of the ischium (HP:0003174)1.75043469
113Bicuspid aortic valve (HP:0001647)1.75017838
114Thickened calvaria (HP:0002684)1.74938766
115Gastrointestinal infarctions (HP:0005244)1.74880188
116Increased neuronal autofluorescent lipopigment (HP:0002074)1.74733389
117Blue sclerae (HP:0000592)1.74298516
118Skin ulcer (HP:0200042)1.73862668
119Verrucae (HP:0200043)1.73631548
120Papilloma (HP:0012740)1.73631548
121Polycythemia (HP:0001901)1.73434186
122Elevated erythrocyte sedimentation rate (HP:0003565)1.73433681
123Metaphyseal cupping (HP:0003021)1.73055064
124Abnormality of the peritoneum (HP:0002585)1.72406665
125Panhypogammaglobulinemia (HP:0003139)1.72258799
126Increased cerebral lipofuscin (HP:0011813)1.72074175
127Gastrointestinal inflammation (HP:0004386)1.71460990
128Restrictive lung disease (HP:0002091)1.71296541
129Femoral bowing (HP:0002980)1.71145431
130Coarse hair (HP:0002208)1.71132555
131Hematochezia (HP:0002573)1.69299073
132Asymmetric septal hypertrophy (HP:0001670)1.68988908
133Thoracolumbar scoliosis (HP:0002944)1.68863680
134Arterial tortuosity (HP:0005116)1.68468789
135Esophageal varix (HP:0002040)1.68230797
136Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.68062878
137Glomerulopathy (HP:0100820)1.67859219
138Interstitial pulmonary disease (HP:0006530)1.67623646
139Abnormality of the left ventricular outflow tract (HP:0011103)1.66935072
140Subaortic stenosis (HP:0001682)1.66935072
141Optic neuritis (HP:0100653)1.66395695
142Retrobulbar optic neuritis (HP:0100654)1.66395695
143Deep venous thrombosis (HP:0002625)1.66359709
144Acrocyanosis (HP:0001063)1.66108184
145Amyloidosis (HP:0011034)1.65620517
146Aneurysm (HP:0002617)1.65468528
147Broad metatarsal (HP:0001783)1.65323158
148Thick nail (HP:0001805)1.65052126
149Abnormality of the radial head (HP:0003995)1.64208340
150Purpura (HP:0000979)1.63103679
151Abnormality of the prostate (HP:0008775)1.62861565
152Abnormality of the distal phalanges of the toes (HP:0010182)1.61485457
153Coxa vara (HP:0002812)1.59834572
154Increased IgE level (HP:0003212)1.59759021
155Tibial bowing (HP:0002982)1.59414376
156Cellulitis (HP:0100658)1.58295450
157Abnormal delayed hypersensitivity skin test (HP:0002963)1.57202836
158Abnormality of the hip-girdle musculature (HP:0001445)1.57199274
159Abnormality of the musculature of the pelvis (HP:0001469)1.57199274
160Dislocated radial head (HP:0003083)1.56999959

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B4.06166082
2EEF2K3.87543665
3MAP2K32.99305118
4MAPKAPK32.94575557
5NUAK12.68629354
6MAP3K62.58299198
7RIPK42.42549342
8TGFBR22.42171662
9TRIB32.37915804
10TRPM72.17382691
11LATS12.09686006
12PKN22.09084576
13MAP3K32.07558099
14TBK12.05246074
15SIK32.01994380
16RIPK11.90961629
17RPS6KA41.86518047
18TTN1.84932910
19STK101.79341793
20BMPR21.73291054
21MAP3K101.70841496
22MOS1.65550704
23TAOK21.64772834
24DDR21.63918524
25IRAK21.61473741
26DYRK1B1.54465321
27MAP4K11.51535723
28JAK31.44764819
29CDK121.44438455
30TAOK31.40280592
31IKBKB1.40102457
32ZAP701.38951888
33KIT1.36638700
34RPS6KB21.36145717
35MAP3K141.35815206
36MAP3K131.33618273
37HIPK21.32982036
38STK31.31299436
39MAP3K111.31177330
40BRD41.29709064
41TNIK1.25978697
42FLT31.24136810
43MARK21.23954822
44CDK61.23640891
45WNK11.23461457
46CHUK1.20153397
47TGFBR11.17715416
48NLK1.17248603
49BLK1.16813284
50BMX1.16157587
51IKBKE1.15858122
52ERN11.14539402
53LRRK21.09028890
54PIM21.08408765
55CSK1.06453248
56PRKD21.06037941
57DMPK1.04876941
58STK41.04643261
59CSF1R1.03735559
60NME21.01583377
61IRAK41.01280429
62SIK11.01023203
63PIM10.98383273
64PIK3CG0.97844084
65ERBB30.96422557
66MAP3K10.96245213
67SIK20.92665831
68SYK0.91114132
69MAP3K50.89431983
70PTK60.88999935
71DYRK30.87286713
72CDC42BPA0.84407569
73IRAK10.84165609
74CDK30.82662675
75MATK0.82077681
76TYK20.81366841
77TESK10.79716698
78IRAK30.77599675
79SGK30.76091098
80HCK0.75008352
81ICK0.73569221
82MELK0.73021320
83KSR20.72638963
84PDGFRA0.72334350
85PAK20.71804955
86EPHB10.69041673
87SMG10.68782099
88FES0.67714597
89PDGFRB0.66496827
90MAP3K70.65055671
91MUSK0.64534923
92MAP3K20.64301102
93MST1R0.64024576
94PDK20.63388880
95GRK70.63306947
96MTOR0.61667630
97FGR0.61044115
98GRK60.60601776
99YES10.60500383
100PDK30.60042235
101PDK40.60042235
102CDK40.58518933
103RPS6KC10.58516739
104RPS6KL10.58516739
105TEC0.57174508
106LATS20.55769468
107STK240.55485968
108NEK90.55005435
109PDPK10.54764375
110EPHA20.54690633
111AKT30.53990774
112BTK0.53510279
113NEK20.53303328
114MAPKAPK20.52784801
115PDK10.52372107
116MARK30.51363915
117LCK0.50980405
118JAK10.49962722
119JAK20.49938578
120ITK0.49262516
121EGFR0.48402305
122GSK3A0.47578382
123PRKG20.47242524
124FER0.46997961
125TAOK10.44892369
126EPHB20.42275753
127MAPK150.40787526
128MAPK110.40673549
129MAPK70.40407620
130LYN0.40252530
131CDK90.38689964
132MAPK120.37797765
133FGFR30.37669213
134PTK2B0.37428355
135TYRO30.37210082
136ABL10.36985599
137PAK40.36905726

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.42722919
2Osteoclast differentiation_Homo sapiens_hsa043802.20036285
3Malaria_Homo sapiens_hsa051442.07437913
4Other glycan degradation_Homo sapiens_hsa005112.05040181
5Toll-like receptor signaling pathway_Homo sapiens_hsa046201.96964209
6TNF signaling pathway_Homo sapiens_hsa046681.93893635
7AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.88121552
8Measles_Homo sapiens_hsa051621.82464043
9RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.82315708
10Small cell lung cancer_Homo sapiens_hsa052221.81362572
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.75223707
12Toxoplasmosis_Homo sapiens_hsa051451.73590387
13Adherens junction_Homo sapiens_hsa045201.69597444
14Chronic myeloid leukemia_Homo sapiens_hsa052201.69125054
15Non-small cell lung cancer_Homo sapiens_hsa052231.66999713
16Legionellosis_Homo sapiens_hsa051341.66432490
17ECM-receptor interaction_Homo sapiens_hsa045121.55529433
18Renal cell carcinoma_Homo sapiens_hsa052111.54775623
19Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.53198707
20Influenza A_Homo sapiens_hsa051641.51266466
21Apoptosis_Homo sapiens_hsa042101.50419554
22Herpes simplex infection_Homo sapiens_hsa051681.50188294
23Viral myocarditis_Homo sapiens_hsa054161.50025746
24Shigellosis_Homo sapiens_hsa051311.48816517
25Asthma_Homo sapiens_hsa053101.48158856
26Acute myeloid leukemia_Homo sapiens_hsa052211.44074229
27Salmonella infection_Homo sapiens_hsa051321.41243469
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.39878035
29B cell receptor signaling pathway_Homo sapiens_hsa046621.39249281
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.38779354
31Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.37676448
32TGF-beta signaling pathway_Homo sapiens_hsa043501.37111481
33Hematopoietic cell lineage_Homo sapiens_hsa046401.36076206
34Amoebiasis_Homo sapiens_hsa051461.34184876
35Autoimmune thyroid disease_Homo sapiens_hsa053201.32161252
36Proteoglycans in cancer_Homo sapiens_hsa052051.31464928
37Pertussis_Homo sapiens_hsa051331.28234593
38p53 signaling pathway_Homo sapiens_hsa041151.27461691
39Tuberculosis_Homo sapiens_hsa051521.27231333
40Focal adhesion_Homo sapiens_hsa045101.27064195
41Hepatitis B_Homo sapiens_hsa051611.26204653
42Selenocompound metabolism_Homo sapiens_hsa004501.20995702
43Notch signaling pathway_Homo sapiens_hsa043301.20178507
44Platelet activation_Homo sapiens_hsa046111.19352093
45Pancreatic cancer_Homo sapiens_hsa052121.17355718
46MicroRNAs in cancer_Homo sapiens_hsa052061.16611501
47Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.15444580
48Graft-versus-host disease_Homo sapiens_hsa053321.14047695
49Primary immunodeficiency_Homo sapiens_hsa053401.12539195
50Jak-STAT signaling pathway_Homo sapiens_hsa046301.09548713
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.09230256
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08166988
53Hepatitis C_Homo sapiens_hsa051601.07121295
54Antigen processing and presentation_Homo sapiens_hsa046121.06938234
55T cell receptor signaling pathway_Homo sapiens_hsa046601.00458108
56Viral carcinogenesis_Homo sapiens_hsa052030.97621901
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.97490697
58Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.97023630
59FoxO signaling pathway_Homo sapiens_hsa040680.93488838
60Rheumatoid arthritis_Homo sapiens_hsa053230.92673288
61HTLV-I infection_Homo sapiens_hsa051660.92521893
62Bladder cancer_Homo sapiens_hsa052190.92137028
63Prostate cancer_Homo sapiens_hsa052150.90687752
64Insulin resistance_Homo sapiens_hsa049310.90677522
65Prolactin signaling pathway_Homo sapiens_hsa049170.89895595
66ErbB signaling pathway_Homo sapiens_hsa040120.89606461
67Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.88974590
68Hippo signaling pathway_Homo sapiens_hsa043900.88923011
69Staphylococcus aureus infection_Homo sapiens_hsa051500.85865701
70Caffeine metabolism_Homo sapiens_hsa002320.84562381
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84520600
72Allograft rejection_Homo sapiens_hsa053300.82271435
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.80537450
74Choline metabolism in cancer_Homo sapiens_hsa052310.80112492
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.79439801
76Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77357927
77Protein digestion and absorption_Homo sapiens_hsa049740.77126034
78Glioma_Homo sapiens_hsa052140.76755484
79mTOR signaling pathway_Homo sapiens_hsa041500.76714107
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.75925021
81VEGF signaling pathway_Homo sapiens_hsa043700.75725830
82Type I diabetes mellitus_Homo sapiens_hsa049400.74700675
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.74632612
84Phagosome_Homo sapiens_hsa041450.73764291
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.73724485
86GnRH signaling pathway_Homo sapiens_hsa049120.73701661
87Lysosome_Homo sapiens_hsa041420.72982182
88Dorso-ventral axis formation_Homo sapiens_hsa043200.72727728
89Colorectal cancer_Homo sapiens_hsa052100.71908825
90Systemic lupus erythematosus_Homo sapiens_hsa053220.70438436
91Basal cell carcinoma_Homo sapiens_hsa052170.70095676
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.69588435
93MAPK signaling pathway_Homo sapiens_hsa040100.68622031
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.68481249
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68244638
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68025732
97Endocytosis_Homo sapiens_hsa041440.66191774
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.64307987
99HIF-1 signaling pathway_Homo sapiens_hsa040660.64068568
100Prion diseases_Homo sapiens_hsa050200.61998441
101PI3K-Akt signaling pathway_Homo sapiens_hsa041510.61397045
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61321342
103Pathways in cancer_Homo sapiens_hsa052000.60234047
104Fatty acid biosynthesis_Homo sapiens_hsa000610.59877146
105Inositol phosphate metabolism_Homo sapiens_hsa005620.59206669
106Glycosaminoglycan degradation_Homo sapiens_hsa005310.58796870
107Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57188365
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56029692
109Lysine degradation_Homo sapiens_hsa003100.55072275
110Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.54822195
111Chemokine signaling pathway_Homo sapiens_hsa040620.54739224
112Estrogen signaling pathway_Homo sapiens_hsa049150.54675518
113Central carbon metabolism in cancer_Homo sapiens_hsa052300.54309252
114African trypanosomiasis_Homo sapiens_hsa051430.51680700
115Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50459590
116Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50024324
117Epstein-Barr virus infection_Homo sapiens_hsa051690.48055088
118Thyroid cancer_Homo sapiens_hsa052160.47868048
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47552165
120Endometrial cancer_Homo sapiens_hsa052130.46754450
121ABC transporters_Homo sapiens_hsa020100.45483747
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42383039

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