Rank | Gene Set | Z-score |
---|---|---|
1 | response to muramyl dipeptide (GO:0032495) | 4.10882277 |
2 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.57651053 |
3 | positive regulation of p38MAPK cascade (GO:1900745) | 3.47071923 |
4 | neutrophil activation involved in immune response (GO:0002283) | 3.46485034 |
5 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 3.38553236 |
6 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.34945857 |
7 | cellular extravasation (GO:0045123) | 3.31404862 |
8 | detection of other organism (GO:0098543) | 3.21102064 |
9 | pinocytosis (GO:0006907) | 3.21056913 |
10 | hypotonic response (GO:0006971) | 3.12239014 |
11 | detection of bacterium (GO:0016045) | 3.11542462 |
12 | positive regulation of interferon-alpha production (GO:0032727) | 3.10441408 |
13 | positive regulation of B cell differentiation (GO:0045579) | 3.09634822 |
14 | germinal center formation (GO:0002467) | 3.09591623 |
15 | membrane raft organization (GO:0031579) | 3.08328996 |
16 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.08185234 |
17 | regulation of chromatin binding (GO:0035561) | 3.04135181 |
18 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.04116140 |
19 | wound healing, spreading of epidermal cells (GO:0035313) | 3.02519751 |
20 | hepatocyte apoptotic process (GO:0097284) | 2.99864431 |
21 | macrophage activation involved in immune response (GO:0002281) | 2.98986482 |
22 | positive regulation by symbiont of host defense response (GO:0052509) | 2.98816376 |
23 | modulation by symbiont of host defense response (GO:0052031) | 2.98816376 |
24 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.98816376 |
25 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.98816376 |
26 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.98816376 |
27 | modulation by symbiont of host immune response (GO:0052553) | 2.98816376 |
28 | germ cell migration (GO:0008354) | 2.96844728 |
29 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.95926889 |
30 | regulation of integrin activation (GO:0033623) | 2.95050655 |
31 | regulation of interferon-alpha production (GO:0032647) | 2.91282704 |
32 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.90326744 |
33 | erythrocyte maturation (GO:0043249) | 2.87589912 |
34 | definitive hemopoiesis (GO:0060216) | 2.84587174 |
35 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.83712892 |
36 | response to host (GO:0075136) | 2.83712892 |
37 | response to host defenses (GO:0052200) | 2.83712892 |
38 | negative regulation of interleukin-8 production (GO:0032717) | 2.82306534 |
39 | tolerance induction (GO:0002507) | 2.81098602 |
40 | B cell receptor signaling pathway (GO:0050853) | 2.79452521 |
41 | skin morphogenesis (GO:0043589) | 2.76997048 |
42 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.76931957 |
43 | regulation of p38MAPK cascade (GO:1900744) | 2.76792290 |
44 | negative regulation of interleukin-12 production (GO:0032695) | 2.76494524 |
45 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.75192938 |
46 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.74777665 |
47 | response to interferon-alpha (GO:0035455) | 2.74009450 |
48 | cellular response to fluid shear stress (GO:0071498) | 2.72819811 |
49 | regulation of leukocyte degranulation (GO:0043300) | 2.70678040 |
50 | hemidesmosome assembly (GO:0031581) | 2.70585315 |
51 | regulation of mast cell degranulation (GO:0043304) | 2.69794503 |
52 | mRNA transcription (GO:0009299) | 2.69217155 |
53 | positive thymic T cell selection (GO:0045059) | 2.68558911 |
54 | detection of external biotic stimulus (GO:0098581) | 2.63067776 |
55 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.62027291 |
56 | apoptotic cell clearance (GO:0043277) | 2.60605437 |
57 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.60495280 |
58 | regulation of RIG-I signaling pathway (GO:0039535) | 2.60380577 |
59 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.59779716 |
60 | B cell homeostasis (GO:0001782) | 2.59460068 |
61 | natural killer cell differentiation (GO:0001779) | 2.59100603 |
62 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.56550064 |
63 | negative regulation of interleukin-6 production (GO:0032715) | 2.56232283 |
64 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.55112707 |
65 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.55088258 |
66 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.54858264 |
67 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.52414946 |
68 | response to host immune response (GO:0052572) | 2.52414946 |
69 | regulation of vitamin metabolic process (GO:0030656) | 2.51446728 |
70 | response to laminar fluid shear stress (GO:0034616) | 2.51327363 |
71 | fibroblast migration (GO:0010761) | 2.50960442 |
72 | immunoglobulin mediated immune response (GO:0016064) | 2.50349086 |
73 | cell adhesion mediated by integrin (GO:0033627) | 2.49167846 |
74 | mannose metabolic process (GO:0006013) | 2.48373282 |
75 | granulocyte activation (GO:0036230) | 2.46078155 |
76 | regulation of B cell differentiation (GO:0045577) | 2.45805585 |
77 | cellular response to exogenous dsRNA (GO:0071360) | 2.45770829 |
78 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 2.45486840 |
79 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.44794325 |
80 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.44101468 |
81 | detection of molecule of bacterial origin (GO:0032490) | 2.43919994 |
82 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.43805898 |
83 | detection of biotic stimulus (GO:0009595) | 2.43676266 |
84 | regulation of monocyte differentiation (GO:0045655) | 2.43499278 |
85 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.43433104 |
86 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.43334224 |
87 | regulation of necroptotic process (GO:0060544) | 2.42785780 |
88 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.42626587 |
89 | myeloid cell activation involved in immune response (GO:0002275) | 2.42528898 |
90 | neutrophil mediated immunity (GO:0002446) | 2.42041725 |
91 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.41701787 |
92 | negative regulation of fatty acid transport (GO:2000192) | 2.41291340 |
93 | monocyte chemotaxis (GO:0002548) | 2.40604194 |
94 | response to protozoan (GO:0001562) | 2.40485836 |
95 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.39586912 |
96 | stress fiber assembly (GO:0043149) | 2.39240532 |
97 | neutrophil activation (GO:0042119) | 2.38654508 |
98 | regulation of macrophage cytokine production (GO:0010935) | 2.38239665 |
99 | leukocyte aggregation (GO:0070486) | 2.37089044 |
100 | protein localization to endosome (GO:0036010) | 2.37060562 |
101 | macrophage chemotaxis (GO:0048246) | 2.36559587 |
102 | positive regulation of granulocyte differentiation (GO:0030854) | 2.35563998 |
103 | megakaryocyte development (GO:0035855) | 2.35128124 |
104 | positive regulation of lipid storage (GO:0010884) | 2.34949879 |
105 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.34581200 |
106 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.33617153 |
107 | positive regulation of extracellular matrix organization (GO:1903055) | 2.33033271 |
108 | negative regulation of granulocyte differentiation (GO:0030853) | 2.33005208 |
109 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.32758425 |
110 | response to fluid shear stress (GO:0034405) | 2.32465794 |
111 | cellular response to virus (GO:0098586) | 2.32447241 |
112 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.31213824 |
113 | negative regulation of cell killing (GO:0031342) | 2.31191842 |
114 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.31191842 |
115 | embryonic process involved in female pregnancy (GO:0060136) | 2.31059956 |
116 | endodermal cell differentiation (GO:0035987) | 2.30026459 |
117 | defense response to protozoan (GO:0042832) | 2.27827389 |
118 | negative regulation of necroptotic process (GO:0060546) | 2.27199991 |
119 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.25422892 |
120 | cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) | 2.25278456 |
121 | positive regulation of histone deacetylation (GO:0031065) | 2.25174170 |
122 | negative regulation of interleukin-17 production (GO:0032700) | 2.24677108 |
123 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.24393411 |
124 | response to peptidoglycan (GO:0032494) | 2.24176713 |
125 | response to type I interferon (GO:0034340) | 2.23845171 |
126 | regulation of interleukin-6 production (GO:0032675) | 2.23536761 |
127 | response to exogenous dsRNA (GO:0043330) | 2.23019699 |
128 | positive regulation of erythrocyte differentiation (GO:0045648) | 2.22957095 |
129 | interferon-gamma secretion (GO:0072643) | 2.22521154 |
130 | modulation by symbiont of host cellular process (GO:0044068) | 2.22092364 |
131 | dosage compensation (GO:0007549) | 2.21807534 |
132 | membrane protein intracellular domain proteolysis (GO:0031293) | 2.20342695 |
133 | regulation of gamma-delta T cell activation (GO:0046643) | 2.20311177 |
134 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.20284125 |
135 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 2.19230672 |
136 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.17962447 |
137 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.17939201 |
138 | positive regulation of myotube differentiation (GO:0010831) | 2.17323928 |
139 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.16718389 |
140 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.15783688 |
141 | genitalia morphogenesis (GO:0035112) | 2.15651174 |
142 | regulation of mononuclear cell migration (GO:0071675) | 2.15364452 |
143 | epithelial cell-cell adhesion (GO:0090136) | 2.14983328 |
144 | wound healing, spreading of cells (GO:0044319) | 2.14706351 |
145 | regulation of erythrocyte differentiation (GO:0045646) | 2.13918415 |
146 | NIK/NF-kappaB signaling (GO:0038061) | 2.13910539 |
147 | regulation of podosome assembly (GO:0071801) | 2.13564421 |
148 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.13038741 |
149 | cellular response to type I interferon (GO:0071357) | 2.12852704 |
150 | type I interferon signaling pathway (GO:0060337) | 2.12852704 |
151 | positive regulation of interferon-beta production (GO:0032728) | 2.12764203 |
152 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.11397977 |
153 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.10177355 |
154 | negative regulation of bone mineralization (GO:0030502) | 2.10161066 |
155 | establishment of endothelial barrier (GO:0061028) | 2.10031716 |
156 | negative regulation of stress fiber assembly (GO:0051497) | 2.09511536 |
157 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.07740189 |
158 | hippo signaling (GO:0035329) | 2.06023327 |
159 | cell-substrate junction assembly (GO:0007044) | 2.05720977 |
160 | low-density lipoprotein particle clearance (GO:0034383) | 2.05369824 |
161 | ectoderm development (GO:0007398) | 2.05286152 |
162 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.04116212 |
163 | acrosome reaction (GO:0007340) | 2.03887358 |
164 | positive T cell selection (GO:0043368) | 2.03644446 |
165 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.03639696 |
166 | desmosome organization (GO:0002934) | 2.03517227 |
167 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.03151551 |
168 | bone remodeling (GO:0046849) | 2.02961606 |
169 | basement membrane organization (GO:0071711) | 2.00846811 |
170 | cyclooxygenase pathway (GO:0019371) | 2.00190176 |
171 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.00001947 |
172 | vascular endothelial growth factor signaling pathway (GO:0038084) | 1.99715007 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.78737864 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.73088808 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.30551620 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.99219833 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.73833289 |
6 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.71852021 |
7 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.70233139 |
8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.69994841 |
9 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.47696526 |
10 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.24761021 |
11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.20251271 |
12 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.19541049 |
13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.19066393 |
14 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.15505750 |
15 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 2.14457624 |
16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.14157675 |
17 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.02276303 |
18 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.02073938 |
19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.99556678 |
20 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.96741681 |
21 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.95609971 |
22 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.93244088 |
23 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.91233321 |
24 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.91208220 |
25 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.90533377 |
26 | MAF_26560356_Chip-Seq_TH1_Human | 1.87877747 |
27 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.87207826 |
28 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.84710691 |
29 | MYC_22102868_ChIP-Seq_BL_Human | 1.80966696 |
30 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.80122309 |
31 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.76777266 |
32 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.73503800 |
33 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.69499278 |
34 | * HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.68283135 |
35 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.68199526 |
36 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.67031064 |
37 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.66028661 |
38 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.63327849 |
39 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.61224762 |
40 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.60397547 |
41 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.56730737 |
42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.54707043 |
43 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.53020203 |
44 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.52526765 |
45 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.50944890 |
46 | MYB_26560356_Chip-Seq_TH2_Human | 1.50005891 |
47 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.48978403 |
48 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.48595720 |
49 | * PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.48066551 |
50 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.46326647 |
51 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.44975900 |
52 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.43940194 |
53 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.43940194 |
54 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.43819898 |
55 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.41975864 |
56 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.41323556 |
57 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40738882 |
58 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39577869 |
59 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.36901470 |
60 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.36578097 |
61 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.36115621 |
62 | MAF_26560356_Chip-Seq_TH2_Human | 1.32987963 |
63 | * MYB_26560356_Chip-Seq_TH1_Human | 1.31849295 |
64 | ATF3_27146783_Chip-Seq_COLON_Human | 1.31719557 |
65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.31562890 |
66 | CJUN_26792858_Chip-Seq_BT549_Human | 1.31205432 |
67 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.30974740 |
68 | * FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.30238434 |
69 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.29242395 |
70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.27396603 |
71 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.25622522 |
72 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.24335152 |
73 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.24069783 |
74 | * GATA2_19941826_ChIP-Seq_K562_Human | 1.21924346 |
75 | GATA1_19941826_ChIP-Seq_K562_Human | 1.20028248 |
76 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.19743145 |
77 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.19111810 |
78 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.17827662 |
79 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.17082121 |
80 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.16855247 |
81 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.16689816 |
82 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.16269927 |
83 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.15515690 |
84 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.14495225 |
85 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13457990 |
86 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.12561883 |
87 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.12127499 |
88 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.11755186 |
89 | * NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.11008419 |
90 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09673948 |
91 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.09664000 |
92 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.09615374 |
93 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09090059 |
94 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.08311776 |
95 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.06751198 |
96 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.06214544 |
97 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.05272184 |
98 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.04343592 |
99 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.04331359 |
100 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.02930468 |
101 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.01969800 |
102 | GATA1_22025678_ChIP-Seq_K562_Human | 1.01936600 |
103 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01467966 |
104 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.01043860 |
105 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.99464566 |
106 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.99253361 |
107 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.99225146 |
108 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.99048100 |
109 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.98855274 |
110 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.98789406 |
111 | SPI1_23127762_ChIP-Seq_K562_Human | 0.98772887 |
112 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98206040 |
113 | * JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98024559 |
114 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.97986184 |
115 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.97680412 |
116 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.97680412 |
117 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.97659987 |
118 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.97363809 |
119 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.97274293 |
120 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.94649640 |
121 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93539055 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.12357767 |
2 | MP0003303_peritoneal_inflammation | 2.83413978 |
3 | MP0003436_decreased_susceptibility_to | 2.47943976 |
4 | MP0003300_gastrointestinal_ulcer | 2.31333130 |
5 | MP0008438_abnormal_cutaneous_collagen | 2.29206687 |
6 | MP0003191_abnormal_cellular_cholesterol | 2.26713210 |
7 | MP0005275_abnormal_skin_tensile | 2.07714897 |
8 | MP0010352_gastrointestinal_tract_polyps | 1.94260924 |
9 | MP0005058_abnormal_lysosome_morphology | 1.91441799 |
10 | MP0009278_abnormal_bone_marrow | 1.89128868 |
11 | MP0003566_abnormal_cell_adhesion | 1.87158447 |
12 | MP0002877_abnormal_melanocyte_morpholog | 1.82322336 |
13 | MP0003950_abnormal_plasma_membrane | 1.72885318 |
14 | MP0005409_darkened_coat_color | 1.71820096 |
15 | MP0003279_aneurysm | 1.71271779 |
16 | MP0005023_abnormal_wound_healing | 1.69481871 |
17 | MP0000685_abnormal_immune_system | 1.66646044 |
18 | MP0002254_reproductive_system_inflammat | 1.64432761 |
19 | MP0005257_abnormal_intraocular_pressure | 1.61241973 |
20 | MP0003172_abnormal_lysosome_physiology | 1.60646521 |
21 | MP0005451_abnormal_body_composition | 1.59127920 |
22 | MP0003091_abnormal_cell_migration | 1.58534395 |
23 | MP0005397_hematopoietic_system_phenotyp | 1.51471998 |
24 | MP0001545_abnormal_hematopoietic_system | 1.51471998 |
25 | MP0005076_abnormal_cell_differentiation | 1.48291146 |
26 | MP0003828_pulmonary_edema | 1.47509483 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.45888966 |
28 | MP0004947_skin_inflammation | 1.44678227 |
29 | MP0002933_joint_inflammation | 1.41401214 |
30 | MP0009840_abnormal_foam_cell | 1.40775424 |
31 | MP0002405_respiratory_system_inflammati | 1.39594305 |
32 | MP0004808_abnormal_hematopoietic_stem | 1.39177011 |
33 | MP0003763_abnormal_thymus_physiology | 1.38349192 |
34 | MP0005464_abnormal_platelet_physiology | 1.38244736 |
35 | MP0005000_abnormal_immune_tolerance | 1.37659761 |
36 | MP0001853_heart_inflammation | 1.36793086 |
37 | MP0003453_abnormal_keratinocyte_physiol | 1.36717666 |
38 | MP0006082_CNS_inflammation | 1.35400507 |
39 | MP0005164_abnormal_response_to | 1.35334280 |
40 | MP0001533_abnormal_skeleton_physiology | 1.33674020 |
41 | MP0001835_abnormal_antigen_presentation | 1.32841112 |
42 | MP0009785_altered_susceptibility_to | 1.29985686 |
43 | MP0002060_abnormal_skin_morphology | 1.28811388 |
44 | MP0000767_abnormal_smooth_muscle | 1.26368028 |
45 | MP0003724_increased_susceptibility_to | 1.25680848 |
46 | MP0002452_abnormal_antigen_presenting | 1.24323083 |
47 | MP0003045_fibrosis | 1.23914243 |
48 | MP0003448_altered_tumor_morphology | 1.23550997 |
49 | MP0002419_abnormal_innate_immunity | 1.21738892 |
50 | MP0005623_abnormal_meninges_morphology | 1.21169713 |
51 | MP0000343_altered_response_to | 1.20710286 |
52 | MP0005025_abnormal_response_to | 1.19812480 |
53 | MP0000733_abnormal_muscle_development | 1.18201563 |
54 | MP0009333_abnormal_splenocyte_physiolog | 1.17289020 |
55 | MP0002148_abnormal_hypersensitivity_rea | 1.16265997 |
56 | MP0004185_abnormal_adipocyte_glucose | 1.14182948 |
57 | MP0008961_abnormal_basal_metabolism | 1.13968695 |
58 | MP0005410_abnormal_fertilization | 1.13851250 |
59 | MP0002998_abnormal_bone_remodeling | 1.12114983 |
60 | MP0002723_abnormal_immune_serum | 1.11946861 |
61 | MP0000371_diluted_coat_color | 1.10355206 |
62 | MP0002168_other_aberrant_phenotype | 1.10246877 |
63 | MP0009053_abnormal_anal_canal | 1.09000738 |
64 | MP0004883_abnormal_blood_vessel | 1.08790249 |
65 | MP0010155_abnormal_intestine_physiology | 1.08350837 |
66 | MP0000490_abnormal_crypts_of | 1.08319596 |
67 | MP0005390_skeleton_phenotype | 1.08103453 |
68 | MP0003252_abnormal_bile_duct | 1.06987127 |
69 | MP0002398_abnormal_bone_marrow | 1.06050582 |
70 | MP0001800_abnormal_humoral_immune | 1.05760741 |
71 | MP0005671_abnormal_response_to | 1.04193945 |
72 | MP0002420_abnormal_adaptive_immunity | 1.04005665 |
73 | MP0001819_abnormal_immune_cell | 1.03526484 |
74 | MP0003567_abnormal_fetal_cardiomyocyte | 1.02315030 |
75 | MP0000689_abnormal_spleen_morphology | 1.01854621 |
76 | MP0000858_altered_metastatic_potential | 1.01753612 |
77 | MP0002006_tumorigenesis | 1.00733235 |
78 | MP0001849_ear_inflammation | 1.00115748 |
79 | MP0004510_myositis | 0.99122322 |
80 | MP0005501_abnormal_skin_physiology | 0.97424059 |
81 | MP0008004_abnormal_stomach_pH | 0.94537265 |
82 | MP0003941_abnormal_skin_development | 0.93818366 |
83 | MP0001851_eye_inflammation | 0.92623769 |
84 | MP0000249_abnormal_blood_vessel | 0.92610148 |
85 | MP0008469_abnormal_protein_level | 0.92592503 |
86 | MP0002282_abnormal_trachea_morphology | 0.92345383 |
87 | MP0002722_abnormal_immune_system | 0.91943855 |
88 | MP0009115_abnormal_fat_cell | 0.91541541 |
89 | MP0001958_emphysema | 0.90700442 |
90 | MP0005666_abnormal_adipose_tissue | 0.89695433 |
91 | MP0003795_abnormal_bone_structure | 0.87270306 |
92 | MP0001790_abnormal_immune_system | 0.86736352 |
93 | MP0005387_immune_system_phenotype | 0.86736352 |
94 | MP0008007_abnormal_cellular_replicative | 0.86475940 |
95 | MP0010234_abnormal_vibrissa_follicle | 0.86200693 |
96 | MP0005621_abnormal_cell_physiology | 0.85772739 |
97 | MP0001243_abnormal_dermal_layer | 0.85371366 |
98 | MP0000716_abnormal_immune_system | 0.85092252 |
99 | MP0002166_altered_tumor_susceptibility | 0.84705602 |
100 | MP0009764_decreased_sensitivity_to | 0.84172675 |
101 | MP0008789_abnormal_olfactory_epithelium | 0.84094512 |
102 | MP0010630_abnormal_cardiac_muscle | 0.84031506 |
103 | MP0002009_preneoplasia | 0.83839086 |
104 | MP0004272_abnormal_basement_membrane | 0.83217950 |
105 | MP0004264_abnormal_extraembryonic_tissu | 0.83043804 |
106 | MP0002396_abnormal_hematopoietic_system | 0.82859112 |
107 | MP0005503_abnormal_tendon_morphology | 0.82018143 |
108 | MP0005508_abnormal_skeleton_morphology | 0.81689788 |
109 | MP0001845_abnormal_inflammatory_respons | 0.80521075 |
110 | MP0001216_abnormal_epidermal_layer | 0.79552746 |
111 | MP0009931_abnormal_skin_appearance | 0.79492011 |
112 | MP0002138_abnormal_hepatobiliary_system | 0.78688798 |
113 | MP0003075_altered_response_to | 0.78223198 |
114 | MP0002115_abnormal_skeleton_extremities | 0.76866099 |
115 | MP0002429_abnormal_blood_cell | 0.76548976 |
116 | MP0003385_abnormal_body_wall | 0.76169906 |
117 | MP0005174_abnormal_tail_pigmentation | 0.76026644 |
118 | MP0001873_stomach_inflammation | 0.75962423 |
119 | MP0010307_abnormal_tumor_latency | 0.75911821 |
120 | MP0005375_adipose_tissue_phenotype | 0.75563848 |
121 | MP0002098_abnormal_vibrissa_morphology | 0.75183512 |
122 | MP0009763_increased_sensitivity_to | 0.74931229 |
123 | MP0002796_impaired_skin_barrier | 0.74378382 |
124 | MP0000703_abnormal_thymus_morphology | 0.72866564 |
125 | MP0001915_intracranial_hemorrhage | 0.69585713 |
126 | MP0000015_abnormal_ear_pigmentation | 0.69570589 |
127 | MP0003221_abnormal_cardiomyocyte_apopto | 0.69371309 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 3.67607164 |
2 | Premature rupture of membranes (HP:0001788) | 3.32594562 |
3 | Increased connective tissue (HP:0009025) | 3.27711453 |
4 | Aortic aneurysm (HP:0004942) | 3.05538072 |
5 | Abnormality of macrophages (HP:0004311) | 3.01479430 |
6 | Syringomyelia (HP:0003396) | 2.95619374 |
7 | Spinal cord lesions (HP:0100561) | 2.95619374 |
8 | Atrophic scars (HP:0001075) | 2.92980319 |
9 | Vertebral compression fractures (HP:0002953) | 2.92791970 |
10 | Recurrent bacterial skin infections (HP:0005406) | 2.82359896 |
11 | Cerebral aneurysm (HP:0004944) | 2.81909253 |
12 | Aortic dissection (HP:0002647) | 2.76732587 |
13 | Pustule (HP:0200039) | 2.73519043 |
14 | Peritonitis (HP:0002586) | 2.73284023 |
15 | Prolonged bleeding time (HP:0003010) | 2.68507960 |
16 | Shallow orbits (HP:0000586) | 2.67555154 |
17 | Ankle contracture (HP:0006466) | 2.59195185 |
18 | Recurrent abscess formation (HP:0002722) | 2.58618510 |
19 | Osteolytic defects of the hand bones (HP:0009699) | 2.56249658 |
20 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.56249658 |
21 | Mitral valve prolapse (HP:0001634) | 2.50181957 |
22 | Epistaxis (HP:0000421) | 2.43982330 |
23 | Autoimmune thrombocytopenia (HP:0001973) | 2.39183118 |
24 | Genu recurvatum (HP:0002816) | 2.38536501 |
25 | Cupped ribs (HP:0000887) | 2.38465059 |
26 | Myocardial infarction (HP:0001658) | 2.36732494 |
27 | Gingival bleeding (HP:0000225) | 2.34816217 |
28 | Absent frontal sinuses (HP:0002688) | 2.34696500 |
29 | Colitis (HP:0002583) | 2.33239347 |
30 | Right ventricular cardiomyopathy (HP:0011663) | 2.32204211 |
31 | Dilatation of the ascending aorta (HP:0005111) | 2.30856902 |
32 | Abnormality of the nasal mucosa (HP:0000433) | 2.29660774 |
33 | Vasculitis (HP:0002633) | 2.28667133 |
34 | Thrombocytosis (HP:0001894) | 2.25948941 |
35 | Fatigue (HP:0012378) | 2.25352319 |
36 | Meningitis (HP:0001287) | 2.24797708 |
37 | Spinal rigidity (HP:0003306) | 2.24504524 |
38 | Nasal polyposis (HP:0100582) | 2.23862207 |
39 | Cervical subluxation (HP:0003308) | 2.22429759 |
40 | Radial bowing (HP:0002986) | 2.20417435 |
41 | Pulmonary infiltrates (HP:0002113) | 2.20331123 |
42 | Dysostosis multiplex (HP:0000943) | 2.20140604 |
43 | Fragile skin (HP:0001030) | 2.20106765 |
44 | Camptodactyly of toe (HP:0001836) | 2.18199678 |
45 | Spontaneous hematomas (HP:0007420) | 2.16572039 |
46 | Disproportionate tall stature (HP:0001519) | 2.16198108 |
47 | Hypoplastic ischia (HP:0003175) | 2.14641411 |
48 | Agammaglobulinemia (HP:0004432) | 2.11627298 |
49 | Prostate neoplasm (HP:0100787) | 2.11540126 |
50 | Eczematoid dermatitis (HP:0000976) | 2.11120598 |
51 | Ulnar bowing (HP:0003031) | 2.11080557 |
52 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.10227130 |
53 | Abnormality of glycolipid metabolism (HP:0010969) | 2.10227130 |
54 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.10227130 |
55 | Epiphyseal dysplasia (HP:0002656) | 2.09012213 |
56 | Viral hepatitis (HP:0006562) | 2.08977091 |
57 | Polygenic inheritance (HP:0010982) | 2.08668028 |
58 | Recurrent skin infections (HP:0001581) | 2.07800601 |
59 | Poikilocytosis (HP:0004447) | 2.06757703 |
60 | Recurrent cutaneous fungal infections (HP:0011370) | 2.04455793 |
61 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.04455793 |
62 | Abnormality of the fingertips (HP:0001211) | 1.99654045 |
63 | Flat acetabular roof (HP:0003180) | 1.97728609 |
64 | Alopecia of scalp (HP:0002293) | 1.97212228 |
65 | Recurrent fungal infections (HP:0002841) | 1.97141614 |
66 | Acute myeloid leukemia (HP:0004808) | 1.96962748 |
67 | Pelvic girdle muscle weakness (HP:0003749) | 1.95369324 |
68 | Abnormality of the acetabulum (HP:0003170) | 1.94982782 |
69 | Subacute progressive viral hepatitis (HP:0006572) | 1.94820138 |
70 | Myositis (HP:0100614) | 1.93344030 |
71 | Increased density of long bones (HP:0006392) | 1.92700840 |
72 | Wormian bones (HP:0002645) | 1.92347497 |
73 | Osteomyelitis (HP:0002754) | 1.91256952 |
74 | Abnormal platelet function (HP:0011869) | 1.91205296 |
75 | Impaired platelet aggregation (HP:0003540) | 1.91205296 |
76 | Urticaria (HP:0001025) | 1.90772055 |
77 | Increased mean platelet volume (HP:0011877) | 1.89923020 |
78 | Soft skin (HP:0000977) | 1.89199630 |
79 | Chronic obstructive pulmonary disease (HP:0006510) | 1.88501065 |
80 | Obstructive lung disease (HP:0006536) | 1.88501065 |
81 | Elbow flexion contracture (HP:0002987) | 1.88398400 |
82 | Recurrent viral infections (HP:0004429) | 1.88206279 |
83 | Abnormal platelet volume (HP:0011876) | 1.87665654 |
84 | Biconcave vertebral bodies (HP:0004586) | 1.87377092 |
85 | Hemorrhage of the eye (HP:0011885) | 1.87289433 |
86 | Long eyelashes (HP:0000527) | 1.85475143 |
87 | Milia (HP:0001056) | 1.85443271 |
88 | Autoimmune hemolytic anemia (HP:0001890) | 1.83625524 |
89 | Inflammation of the large intestine (HP:0002037) | 1.82752766 |
90 | Orchitis (HP:0100796) | 1.82677585 |
91 | Short nail (HP:0001799) | 1.82516169 |
92 | Bowed forearm bones (HP:0003956) | 1.82231877 |
93 | Bowing of the arm (HP:0006488) | 1.82231877 |
94 | Broad face (HP:0000283) | 1.81608468 |
95 | Vacuolated lymphocytes (HP:0001922) | 1.81521550 |
96 | Mitral regurgitation (HP:0001653) | 1.81356360 |
97 | Arterial thrombosis (HP:0004420) | 1.80878057 |
98 | Spondylolisthesis (HP:0003302) | 1.79998812 |
99 | Thin ribs (HP:0000883) | 1.79892423 |
100 | Chest pain (HP:0100749) | 1.79380823 |
101 | Gastrointestinal stroma tumor (HP:0100723) | 1.78822898 |
102 | Obstructive sleep apnea (HP:0002870) | 1.78721653 |
103 | Emphysema (HP:0002097) | 1.78003074 |
104 | Flexion contracture of toe (HP:0005830) | 1.77765215 |
105 | Joint contractures involving the joints of the feet (HP:0100492) | 1.77765215 |
106 | Gingivitis (HP:0000230) | 1.77589500 |
107 | Mediastinal lymphadenopathy (HP:0100721) | 1.77318984 |
108 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.76979233 |
109 | Vascular tortuosity (HP:0004948) | 1.75795914 |
110 | Xerostomia (HP:0000217) | 1.75297188 |
111 | Hypergammaglobulinemia (HP:0010702) | 1.75101417 |
112 | Abnormality of the ischium (HP:0003174) | 1.75043469 |
113 | Bicuspid aortic valve (HP:0001647) | 1.75017838 |
114 | Thickened calvaria (HP:0002684) | 1.74938766 |
115 | Gastrointestinal infarctions (HP:0005244) | 1.74880188 |
116 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.74733389 |
117 | Blue sclerae (HP:0000592) | 1.74298516 |
118 | Skin ulcer (HP:0200042) | 1.73862668 |
119 | Verrucae (HP:0200043) | 1.73631548 |
120 | Papilloma (HP:0012740) | 1.73631548 |
121 | Polycythemia (HP:0001901) | 1.73434186 |
122 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.73433681 |
123 | Metaphyseal cupping (HP:0003021) | 1.73055064 |
124 | Abnormality of the peritoneum (HP:0002585) | 1.72406665 |
125 | Panhypogammaglobulinemia (HP:0003139) | 1.72258799 |
126 | Increased cerebral lipofuscin (HP:0011813) | 1.72074175 |
127 | Gastrointestinal inflammation (HP:0004386) | 1.71460990 |
128 | Restrictive lung disease (HP:0002091) | 1.71296541 |
129 | Femoral bowing (HP:0002980) | 1.71145431 |
130 | Coarse hair (HP:0002208) | 1.71132555 |
131 | Hematochezia (HP:0002573) | 1.69299073 |
132 | Asymmetric septal hypertrophy (HP:0001670) | 1.68988908 |
133 | Thoracolumbar scoliosis (HP:0002944) | 1.68863680 |
134 | Arterial tortuosity (HP:0005116) | 1.68468789 |
135 | Esophageal varix (HP:0002040) | 1.68230797 |
136 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.68062878 |
137 | Glomerulopathy (HP:0100820) | 1.67859219 |
138 | Interstitial pulmonary disease (HP:0006530) | 1.67623646 |
139 | Subaortic stenosis (HP:0001682) | 1.66935072 |
140 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.66935072 |
141 | Retrobulbar optic neuritis (HP:0100654) | 1.66395695 |
142 | Optic neuritis (HP:0100653) | 1.66395695 |
143 | Deep venous thrombosis (HP:0002625) | 1.66359709 |
144 | Acrocyanosis (HP:0001063) | 1.66108184 |
145 | Amyloidosis (HP:0011034) | 1.65620517 |
146 | Aneurysm (HP:0002617) | 1.65468528 |
147 | Broad metatarsal (HP:0001783) | 1.65323158 |
148 | Thick nail (HP:0001805) | 1.65052126 |
149 | Abnormality of the radial head (HP:0003995) | 1.64208340 |
150 | Purpura (HP:0000979) | 1.63103679 |
151 | Abnormality of the prostate (HP:0008775) | 1.62861565 |
152 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.61485457 |
153 | Coxa vara (HP:0002812) | 1.59834572 |
154 | Increased IgE level (HP:0003212) | 1.59759021 |
155 | Tibial bowing (HP:0002982) | 1.59414376 |
156 | Cellulitis (HP:0100658) | 1.58295450 |
157 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.57202836 |
158 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.57199274 |
159 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.57199274 |
160 | Dislocated radial head (HP:0003083) | 1.56999959 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PRPF4B | 4.06166082 |
2 | EEF2K | 3.87543665 |
3 | MAP2K3 | 2.99305118 |
4 | MAPKAPK3 | 2.94575557 |
5 | NUAK1 | 2.68629354 |
6 | MAP3K6 | 2.58299198 |
7 | RIPK4 | 2.42549342 |
8 | TGFBR2 | 2.42171662 |
9 | TRIB3 | 2.37915804 |
10 | TRPM7 | 2.17382691 |
11 | LATS1 | 2.09686006 |
12 | PKN2 | 2.09084576 |
13 | MAP3K3 | 2.07558099 |
14 | TBK1 | 2.05246074 |
15 | SIK3 | 2.01994380 |
16 | RIPK1 | 1.90961629 |
17 | RPS6KA4 | 1.86518047 |
18 | TTN | 1.84932910 |
19 | STK10 | 1.79341793 |
20 | BMPR2 | 1.73291054 |
21 | MAP3K10 | 1.70841496 |
22 | MOS | 1.65550704 |
23 | TAOK2 | 1.64772834 |
24 | DDR2 | 1.63918524 |
25 | IRAK2 | 1.61473741 |
26 | DYRK1B | 1.54465321 |
27 | MAP4K1 | 1.51535723 |
28 | JAK3 | 1.44764819 |
29 | CDK12 | 1.44438455 |
30 | TAOK3 | 1.40280592 |
31 | IKBKB | 1.40102457 |
32 | ZAP70 | 1.38951888 |
33 | KIT | 1.36638700 |
34 | RPS6KB2 | 1.36145717 |
35 | MAP3K14 | 1.35815206 |
36 | MAP3K13 | 1.33618273 |
37 | HIPK2 | 1.32982036 |
38 | STK3 | 1.31299436 |
39 | MAP3K11 | 1.31177330 |
40 | BRD4 | 1.29709064 |
41 | TNIK | 1.25978697 |
42 | FLT3 | 1.24136810 |
43 | MARK2 | 1.23954822 |
44 | CDK6 | 1.23640891 |
45 | WNK1 | 1.23461457 |
46 | CHUK | 1.20153397 |
47 | TGFBR1 | 1.17715416 |
48 | NLK | 1.17248603 |
49 | BLK | 1.16813284 |
50 | BMX | 1.16157587 |
51 | IKBKE | 1.15858122 |
52 | ERN1 | 1.14539402 |
53 | LRRK2 | 1.09028890 |
54 | PIM2 | 1.08408765 |
55 | CSK | 1.06453248 |
56 | PRKD2 | 1.06037941 |
57 | DMPK | 1.04876941 |
58 | STK4 | 1.04643261 |
59 | CSF1R | 1.03735559 |
60 | NME2 | 1.01583377 |
61 | IRAK4 | 1.01280429 |
62 | SIK1 | 1.01023203 |
63 | PIM1 | 0.98383273 |
64 | PIK3CG | 0.97844084 |
65 | ERBB3 | 0.96422557 |
66 | MAP3K1 | 0.96245213 |
67 | SIK2 | 0.92665831 |
68 | SYK | 0.91114132 |
69 | MAP3K5 | 0.89431983 |
70 | PTK6 | 0.88999935 |
71 | DYRK3 | 0.87286713 |
72 | CDC42BPA | 0.84407569 |
73 | IRAK1 | 0.84165609 |
74 | CDK3 | 0.82662675 |
75 | MATK | 0.82077681 |
76 | TYK2 | 0.81366841 |
77 | TESK1 | 0.79716698 |
78 | IRAK3 | 0.77599675 |
79 | SGK3 | 0.76091098 |
80 | HCK | 0.75008352 |
81 | ICK | 0.73569221 |
82 | MELK | 0.73021320 |
83 | KSR2 | 0.72638963 |
84 | PDGFRA | 0.72334350 |
85 | PAK2 | 0.71804955 |
86 | EPHB1 | 0.69041673 |
87 | SMG1 | 0.68782099 |
88 | FES | 0.67714597 |
89 | PDGFRB | 0.66496827 |
90 | MAP3K7 | 0.65055671 |
91 | MUSK | 0.64534923 |
92 | MAP3K2 | 0.64301102 |
93 | MST1R | 0.64024576 |
94 | PDK2 | 0.63388880 |
95 | GRK7 | 0.63306947 |
96 | MTOR | 0.61667630 |
97 | FGR | 0.61044115 |
98 | GRK6 | 0.60601776 |
99 | YES1 | 0.60500383 |
100 | PDK3 | 0.60042235 |
101 | PDK4 | 0.60042235 |
102 | CDK4 | 0.58518933 |
103 | RPS6KL1 | 0.58516739 |
104 | RPS6KC1 | 0.58516739 |
105 | TEC | 0.57174508 |
106 | LATS2 | 0.55769468 |
107 | STK24 | 0.55485968 |
108 | NEK9 | 0.55005435 |
109 | PDPK1 | 0.54764375 |
110 | EPHA2 | 0.54690633 |
111 | AKT3 | 0.53990774 |
112 | BTK | 0.53510279 |
113 | NEK2 | 0.53303328 |
114 | MAPKAPK2 | 0.52784801 |
115 | PDK1 | 0.52372107 |
116 | MARK3 | 0.51363915 |
117 | LCK | 0.50980405 |
118 | JAK1 | 0.49962722 |
119 | JAK2 | 0.49938578 |
120 | ITK | 0.49262516 |
121 | EGFR | 0.48402305 |
122 | GSK3A | 0.47578382 |
123 | PRKG2 | 0.47242524 |
124 | FER | 0.46997961 |
125 | TAOK1 | 0.44892369 |
126 | EPHB2 | 0.42275753 |
127 | MAPK15 | 0.40787526 |
128 | MAPK11 | 0.40673549 |
129 | MAPK7 | 0.40407620 |
130 | LYN | 0.40252530 |
131 | CDK9 | 0.38689964 |
132 | MAPK12 | 0.37797765 |
133 | FGFR3 | 0.37669213 |
134 | PTK2B | 0.37428355 |
135 | TYRO3 | 0.37210082 |
136 | ABL1 | 0.36985599 |
137 | PAK4 | 0.36905726 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.42722919 |
2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.20036285 |
3 | Malaria_Homo sapiens_hsa05144 | 2.07437913 |
4 | Other glycan degradation_Homo sapiens_hsa00511 | 2.05040181 |
5 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.96964209 |
6 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.93893635 |
7 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.88121552 |
8 | Measles_Homo sapiens_hsa05162 | 1.82464043 |
9 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.82315708 |
10 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.81362572 |
11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.75223707 |
12 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.73590387 |
13 | Adherens junction_Homo sapiens_hsa04520 | 1.69597444 |
14 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.69125054 |
15 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.66999713 |
16 | Legionellosis_Homo sapiens_hsa05134 | 1.66432490 |
17 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.55529433 |
18 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.54775623 |
19 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.53198707 |
20 | Influenza A_Homo sapiens_hsa05164 | 1.51266466 |
21 | Apoptosis_Homo sapiens_hsa04210 | 1.50419554 |
22 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.50188294 |
23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.50025746 |
24 | Shigellosis_Homo sapiens_hsa05131 | 1.48816517 |
25 | Asthma_Homo sapiens_hsa05310 | 1.48158856 |
26 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.44074229 |
27 | Salmonella infection_Homo sapiens_hsa05132 | 1.41243469 |
28 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.39878035 |
29 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.39249281 |
30 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.38779354 |
31 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.37676448 |
32 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.37111481 |
33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.36076206 |
34 | Amoebiasis_Homo sapiens_hsa05146 | 1.34184876 |
35 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.32161252 |
36 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.31464928 |
37 | Pertussis_Homo sapiens_hsa05133 | 1.28234593 |
38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.27461691 |
39 | Tuberculosis_Homo sapiens_hsa05152 | 1.27231333 |
40 | Focal adhesion_Homo sapiens_hsa04510 | 1.27064195 |
41 | Hepatitis B_Homo sapiens_hsa05161 | 1.26204653 |
42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.20995702 |
43 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.20178507 |
44 | Platelet activation_Homo sapiens_hsa04611 | 1.19352093 |
45 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.17355718 |
46 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.16611501 |
47 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.15444580 |
48 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.14047695 |
49 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12539195 |
50 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.09548713 |
51 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.09230256 |
52 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.08166988 |
53 | Hepatitis C_Homo sapiens_hsa05160 | 1.07121295 |
54 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.06938234 |
55 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.00458108 |
56 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.97621901 |
57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.97490697 |
58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.97023630 |
59 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.93488838 |
60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.92673288 |
61 | HTLV-I infection_Homo sapiens_hsa05166 | 0.92521893 |
62 | Bladder cancer_Homo sapiens_hsa05219 | 0.92137028 |
63 | Prostate cancer_Homo sapiens_hsa05215 | 0.90687752 |
64 | Insulin resistance_Homo sapiens_hsa04931 | 0.90677522 |
65 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89895595 |
66 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.89606461 |
67 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.88974590 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.88923011 |
69 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.85865701 |
70 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.84562381 |
71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.84520600 |
72 | Allograft rejection_Homo sapiens_hsa05330 | 0.82271435 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.80537450 |
74 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.80112492 |
75 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.79439801 |
76 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.77357927 |
77 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.77126034 |
78 | Glioma_Homo sapiens_hsa05214 | 0.76755484 |
79 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.76714107 |
80 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75925021 |
81 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.75725830 |
82 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.74700675 |
83 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.74632612 |
84 | Phagosome_Homo sapiens_hsa04145 | 0.73764291 |
85 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.73724485 |
86 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.73701661 |
87 | Lysosome_Homo sapiens_hsa04142 | 0.72982182 |
88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.72727728 |
89 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71908825 |
90 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.70438436 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.70095676 |
92 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.69588435 |
93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.68622031 |
94 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.68481249 |
95 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.68244638 |
96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.68025732 |
97 | Endocytosis_Homo sapiens_hsa04144 | 0.66191774 |
98 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.64307987 |
99 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64068568 |
100 | Prion diseases_Homo sapiens_hsa05020 | 0.61998441 |
101 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.61397045 |
102 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.61321342 |
103 | Pathways in cancer_Homo sapiens_hsa05200 | 0.60234047 |
104 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.59877146 |
105 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.59206669 |
106 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.58796870 |
107 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.57188365 |
108 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.56029692 |
109 | Lysine degradation_Homo sapiens_hsa00310 | 0.55072275 |
110 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.54822195 |
111 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.54739224 |
112 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54675518 |
113 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.54309252 |
114 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51680700 |
115 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.50459590 |
116 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50024324 |
117 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48055088 |
118 | Thyroid cancer_Homo sapiens_hsa05216 | 0.47868048 |
119 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47552165 |
120 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46754450 |
121 | ABC transporters_Homo sapiens_hsa02010 | 0.45483747 |
122 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.42383039 |