SESTD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.70978392
2vocalization behavior (GO:0071625)4.69535791
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.65290702
4layer formation in cerebral cortex (GO:0021819)4.60059011
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.19013894
6axonal fasciculation (GO:0007413)4.11159089
7regulation of short-term neuronal synaptic plasticity (GO:0048172)4.11085892
8dendrite morphogenesis (GO:0048813)4.10951228
9cell migration in hindbrain (GO:0021535)4.10041442
10neuron recognition (GO:0008038)4.09088306
11protein localization to synapse (GO:0035418)4.08540136
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.07760795
13synaptic vesicle exocytosis (GO:0016079)4.02958160
14regulation of glutamate receptor signaling pathway (GO:1900449)4.00005251
15dendritic spine morphogenesis (GO:0060997)3.98035526
16synaptic vesicle docking involved in exocytosis (GO:0016081)3.90178451
17presynaptic membrane assembly (GO:0097105)3.85866216
18locomotory exploration behavior (GO:0035641)3.84265288
19regulation of synaptic vesicle exocytosis (GO:2000300)3.78840866
20cerebellar Purkinje cell differentiation (GO:0021702)3.76937790
21ionotropic glutamate receptor signaling pathway (GO:0035235)3.76234792
22glutamate secretion (GO:0014047)3.73837865
23synaptic vesicle maturation (GO:0016188)3.71646601
24glutamate receptor signaling pathway (GO:0007215)3.70916260
25postsynaptic membrane organization (GO:0001941)3.66206571
26presynaptic membrane organization (GO:0097090)3.64539554
27proline transport (GO:0015824)3.58644000
28pyrimidine nucleobase catabolic process (GO:0006208)3.58352205
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.55626157
30axon extension (GO:0048675)3.55537543
31exploration behavior (GO:0035640)3.49055484
32regulation of synapse structural plasticity (GO:0051823)3.49007532
33positive regulation of synapse maturation (GO:0090129)3.40295171
34establishment of nucleus localization (GO:0040023)3.37201284
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.34885280
36central nervous system projection neuron axonogenesis (GO:0021952)3.32319154
37synaptic transmission, glutamatergic (GO:0035249)3.32222790
38response to pheromone (GO:0019236)3.30872944
39regulation of synaptic vesicle transport (GO:1902803)3.30549980
40negative regulation of microtubule polymerization (GO:0031115)3.29470313
41cerebellar granule cell differentiation (GO:0021707)3.28205468
42G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.28173514
43innervation (GO:0060384)3.25801766
44synaptic vesicle endocytosis (GO:0048488)3.17081122
45neuron projection extension (GO:1990138)3.16795475
46neuronal action potential propagation (GO:0019227)3.13931129
47nucleobase catabolic process (GO:0046113)3.12891889
48regulation of dendritic spine morphogenesis (GO:0061001)3.10711281
49neuron-neuron synaptic transmission (GO:0007270)3.09460218
50synapse assembly (GO:0007416)3.01995731
51cellular potassium ion homeostasis (GO:0030007)3.00440211
52neurotransmitter-gated ion channel clustering (GO:0072578)2.97824065
53regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96829004
54neurofilament cytoskeleton organization (GO:0060052)2.96364685
55positive regulation of synapse assembly (GO:0051965)2.95877737
56short-term memory (GO:0007614)2.93825521
57regulation of postsynaptic membrane potential (GO:0060078)2.91511666
58organelle transport along microtubule (GO:0072384)2.90464944
59neurotransmitter secretion (GO:0007269)2.90173213
60clathrin coat assembly (GO:0048268)2.88577492
61regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.84045069
62regulation of long-term neuronal synaptic plasticity (GO:0048169)2.80839112
63membrane depolarization during action potential (GO:0086010)2.80299439
64regulation of synaptic transmission, glutamatergic (GO:0051966)2.79494992
65central nervous system myelination (GO:0022010)2.77151524
66axon ensheathment in central nervous system (GO:0032291)2.77151524
67regulation of meiosis I (GO:0060631)2.77050794
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.76014562
69cell differentiation in hindbrain (GO:0021533)2.75971279
70cochlea development (GO:0090102)2.75568703
71auditory behavior (GO:0031223)2.75269213
72gamma-aminobutyric acid signaling pathway (GO:0007214)2.74537054
73vesicle transport along microtubule (GO:0047496)2.74126217
74positive regulation of dendritic spine development (GO:0060999)2.74053749
75central nervous system neuron axonogenesis (GO:0021955)2.73342451
76regulation of synapse assembly (GO:0051963)2.73187352
77negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.72773011
78synapse organization (GO:0050808)2.71706986
79positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.71413642
80regulation of dendritic spine development (GO:0060998)2.70732317
81regulation of neuronal synaptic plasticity (GO:0048168)2.69864096
82C4-dicarboxylate transport (GO:0015740)2.69523641
83dendritic spine organization (GO:0097061)2.68155749
84response to auditory stimulus (GO:0010996)2.67536940
85cell communication by electrical coupling (GO:0010644)2.65593646
86regulation of neurotransmitter secretion (GO:0046928)2.65259860
87positive regulation of membrane potential (GO:0045838)2.65105760
88positive regulation of axon extension (GO:0045773)2.65000955
89membrane depolarization (GO:0051899)2.64739225
90regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.64312342
91regulation of synapse organization (GO:0050807)2.63756627
92dendrite development (GO:0016358)2.63577461
93neuromuscular process controlling balance (GO:0050885)2.62896329
94hippocampus development (GO:0021766)2.60993611
95negative regulation of dendrite development (GO:2000171)2.59423855
96positive regulation of dendritic spine morphogenesis (GO:0061003)2.58837867
97cerebral cortex cell migration (GO:0021795)2.57324668
98adult walking behavior (GO:0007628)2.56801310
99cerebellum development (GO:0021549)2.56440203
100regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.56426980
101regulation of synapse maturation (GO:0090128)2.54902423
102long-term synaptic potentiation (GO:0060291)2.54750250
103long-term memory (GO:0007616)2.54081585
104membrane hyperpolarization (GO:0060081)2.53824682
105negative regulation of synaptic transmission, GABAergic (GO:0032229)2.53287686
106gamma-aminobutyric acid transport (GO:0015812)2.53040160
107embryonic retina morphogenesis in camera-type eye (GO:0060059)2.52707982
108cerebral cortex radially oriented cell migration (GO:0021799)2.52535922
109positive regulation of filopodium assembly (GO:0051491)2.52521651
110neuron projection morphogenesis (GO:0048812)2.52195044
111prepulse inhibition (GO:0060134)2.50654268
112regulation of respiratory system process (GO:0044065)2.50583191
113nucleus localization (GO:0051647)2.49915016
114transmission of nerve impulse (GO:0019226)2.48118983
115limb bud formation (GO:0060174)2.44747376
116retina layer formation (GO:0010842)2.44518508
117positive regulation of neurological system process (GO:0031646)2.42674427
118regulation of cAMP-dependent protein kinase activity (GO:2000479)2.41207011
119positive regulation of meiosis (GO:0045836)2.37766465
120regulation of axon guidance (GO:1902667)2.37407124
121regulation of non-canonical Wnt signaling pathway (GO:2000050)2.35361992
122establishment of mitochondrion localization (GO:0051654)2.34254401
123regulation of NFAT protein import into nucleus (GO:0051532)2.34193202
124cellular sodium ion homeostasis (GO:0006883)2.33737087
125apical protein localization (GO:0045176)2.33560559
126retinal ganglion cell axon guidance (GO:0031290)2.33092837
127membrane assembly (GO:0071709)2.31718451
128neuronal ion channel clustering (GO:0045161)2.29955990
129calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.28591749
130negative chemotaxis (GO:0050919)2.28023874
131positive regulation of amino acid transport (GO:0051957)2.27009367
132positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.26332312
133mechanosensory behavior (GO:0007638)2.26205724
134nerve growth factor signaling pathway (GO:0038180)2.25109702
135axon extension involved in axon guidance (GO:0048846)2.23971934
136neuron projection extension involved in neuron projection guidance (GO:1902284)2.23971934
137axonogenesis (GO:0007409)2.20470884
138regulation of axon extension involved in axon guidance (GO:0048841)2.19113756
139serotonin metabolic process (GO:0042428)2.18852127
140photoreceptor cell differentiation (GO:0046530)2.18054635
141eye photoreceptor cell differentiation (GO:0001754)2.18054635
142neuron migration (GO:0001764)2.17112330

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.33144544
2GBX2_23144817_ChIP-Seq_PC3_Human3.69879327
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.69428329
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.65165943
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63684597
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42334797
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42334797
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.38149497
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.32945537
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32652903
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26482426
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.23869055
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18189469
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.12840198
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.11659503
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.10905303
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.08723199
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.04720178
19REST_21632747_ChIP-Seq_MESCs_Mouse2.00031301
20RNF2_27304074_Chip-Seq_ESCs_Mouse1.99075606
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97634615
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.92619075
23* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92139735
24SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89146180
25CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84407705
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.84255294
27DROSHA_22980978_ChIP-Seq_HELA_Human1.83600422
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.81268404
29TAF15_26573619_Chip-Seq_HEK293_Human1.80116498
30SMAD4_21799915_ChIP-Seq_A2780_Human1.73753158
31SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.71391303
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.69839965
33AR_21572438_ChIP-Seq_LNCaP_Human1.69661169
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.66042577
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.65671622
36ZNF274_21170338_ChIP-Seq_K562_Hela1.64405355
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.61173272
38RARB_27405468_Chip-Seq_BRAIN_Mouse1.60127345
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60091286
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.57567609
41* P300_19829295_ChIP-Seq_ESCs_Human1.56135496
42CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55287132
43ZNF217_24962896_ChIP-Seq_MCF-7_Human1.53813570
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.47567976
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47302389
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.47035656
47IKZF1_21737484_ChIP-ChIP_HCT116_Human1.46374999
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.46258482
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.45086316
50* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43300317
51BMI1_23680149_ChIP-Seq_NPCS_Mouse1.43132958
52* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42861156
53AHR_22903824_ChIP-Seq_MCF-7_Human1.41441818
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.40684894
55ARNT_22903824_ChIP-Seq_MCF-7_Human1.40527081
56* SMAD3_21741376_ChIP-Seq_EPCs_Human1.39217319
57IGF1R_20145208_ChIP-Seq_DFB_Human1.39116063
58RNF2_27304074_Chip-Seq_NSC_Mouse1.38470760
59* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37902617
60SOX2_21211035_ChIP-Seq_LN229_Gbm1.36702321
61* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36081330
62* AR_25329375_ChIP-Seq_VCAP_Human1.36010931
63CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35974416
64EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35616652
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34945313
66* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.33349723
67SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32073900
68STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.30224897
69* STAT3_23295773_ChIP-Seq_U87_Human1.29953598
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29654257
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29654257
72TP53_16413492_ChIP-PET_HCT116_Human1.27670779
73HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26707633
74WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24063903
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23888360
76VDR_22108803_ChIP-Seq_LS180_Human1.22898433
77FUS_26573619_Chip-Seq_HEK293_Human1.22489370
78* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21887691
79RING1B_27294783_Chip-Seq_ESCs_Mouse1.21785835
80EWS_26573619_Chip-Seq_HEK293_Human1.21514050
81RING1B_27294783_Chip-Seq_NPCs_Mouse1.21506808
82YAP1_20516196_ChIP-Seq_MESCs_Mouse1.20194767
83AR_19668381_ChIP-Seq_PC3_Human1.19084427
84KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18936567
85SALL1_21062744_ChIP-ChIP_HESCs_Human1.18708581
86TP53_18474530_ChIP-ChIP_U2OS_Human1.17783284
87* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17402522
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16073223
89NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.15872945
90NRF2_20460467_ChIP-Seq_MEFs_Mouse1.15872945
91* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15310486
92CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.14719904
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13898155
94MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.12483450
95* TCF4_23295773_ChIP-Seq_U87_Human1.11997734
96* RUNX2_22187159_ChIP-Seq_PCA_Human1.09652430
97EP300_21415370_ChIP-Seq_HL-1_Mouse1.09011651
98GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08877862
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.07215507
100TAL1_26923725_Chip-Seq_HPCs_Mouse1.05417168
101CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05384366
102* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05246683
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04837796
104ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.03484043
105VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.03174983
106ER_23166858_ChIP-Seq_MCF-7_Human1.02675473
107* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01899736
108* SMAD3_21741376_ChIP-Seq_ESCs_Human1.00317393
109TCF4_18268006_ChIP-ChIP_LS174T_Human0.99740632
110BCAT_22108803_ChIP-Seq_LS180_Human0.99316407
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.98185544
112* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97905098
113EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97552461
114WT1_19549856_ChIP-ChIP_CCG9911_Human0.96815244
115* NANOG_18555785_Chip-Seq_ESCs_Mouse0.95916960
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94459912

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.91784332
2MP0003880_abnormal_central_pattern4.07710920
3MP0004270_analgesia3.72290601
4MP0003635_abnormal_synaptic_transmissio3.31125425
5MP0000569_abnormal_digit_pigmentation3.22342967
6MP0000778_abnormal_nervous_system2.84149954
7MP0001968_abnormal_touch/_nociception2.84101922
8MP0002063_abnormal_learning/memory/cond2.80108895
9MP0005423_abnormal_somatic_nervous2.78221612
10MP0002734_abnormal_mechanical_nocicepti2.70795887
11MP0002735_abnormal_chemical_nociception2.56425039
12MP0009046_muscle_twitch2.46773298
13MP0002736_abnormal_nociception_after2.43743815
14MP0009745_abnormal_behavioral_response2.41160642
15MP0000566_synostosis2.40790965
16MP0002184_abnormal_innervation2.27154691
17MP0002572_abnormal_emotion/affect_behav2.26446867
18MP0002064_seizures2.23874584
19MP0004858_abnormal_nervous_system2.18502419
20MP0006276_abnormal_autonomic_nervous2.06360994
21MP0002067_abnormal_sensory_capabilities2.02476804
22MP0001486_abnormal_startle_reflex1.91034938
23MP0002733_abnormal_thermal_nociception1.87204291
24MP0001440_abnormal_grooming_behavior1.79685903
25MP0002272_abnormal_nervous_system1.78573773
26MP0009780_abnormal_chondrocyte_physiolo1.74804873
27MP0001984_abnormal_olfaction1.72299851
28MP0004811_abnormal_neuron_physiology1.71489769
29MP0001970_abnormal_pain_threshold1.64847043
30MP0002557_abnormal_social/conspecific_i1.62256530
31MP0008877_abnormal_DNA_methylation1.61914573
32MP0001501_abnormal_sleep_pattern1.53568385
33MP0000955_abnormal_spinal_cord1.52674585
34MP0008569_lethality_at_weaning1.49225895
35MP0003122_maternal_imprinting1.49189804
36MP0005386_behavior/neurological_phenoty1.48145830
37MP0004924_abnormal_behavior1.48145830
38MP0002882_abnormal_neuron_morphology1.44015657
39MP0010386_abnormal_urinary_bladder1.42834222
40MP0003879_abnormal_hair_cell1.42774313
41MP0005409_darkened_coat_color1.40328955
42MP0000751_myopathy1.39024669
43MP0002822_catalepsy1.38045513
44MP0010234_abnormal_vibrissa_follicle1.35764464
45MP0002638_abnormal_pupillary_reflex1.31712230
46MP0004885_abnormal_endolymph1.31521374
47MP0003123_paternal_imprinting1.29893805
48MP0001299_abnormal_eye_distance/1.28560052
49MP0002152_abnormal_brain_morphology1.25917950
50MP0004742_abnormal_vestibular_system1.25820547
51MP0003329_amyloid_beta_deposits1.23097504
52MP0001502_abnormal_circadian_rhythm1.22638717
53MP0002066_abnormal_motor_capabilities/c1.22065827
54MP0005187_abnormal_penis_morphology1.21796296
55MP0001188_hyperpigmentation1.18775697
56MP0004142_abnormal_muscle_tone1.16552332
57MP0003787_abnormal_imprinting1.16114073
58MP0002909_abnormal_adrenal_gland1.14341420
59MP0005623_abnormal_meninges_morphology1.13991846
60MP0002233_abnormal_nose_morphology1.13784733
61MP0003136_yellow_coat_color1.11709907
62MP0000537_abnormal_urethra_morphology1.08303504
63MP0005171_absent_coat_pigmentation1.08265893
64MP0003690_abnormal_glial_cell1.04905654
65MP0003861_abnormal_nervous_system1.03936031
66MP0000631_abnormal_neuroendocrine_gland1.02441398
67MP0003937_abnormal_limbs/digits/tail_de0.99906999
68MP0003938_abnormal_ear_development0.98866991
69MP0005551_abnormal_eye_electrophysiolog0.97665029
70MP0005645_abnormal_hypothalamus_physiol0.96200316
71MP0003385_abnormal_body_wall0.95886469
72MP0001529_abnormal_vocalization0.94217749
73MP0010368_abnormal_lymphatic_system0.92259663
74MP0000049_abnormal_middle_ear0.90629060
75MP0002938_white_spotting0.90393036
76MP0003121_genomic_imprinting0.90389362
77MP0000534_abnormal_ureter_morphology0.90331025
78MP0000538_abnormal_urinary_bladder0.89378514
79MP0003935_abnormal_craniofacial_develop0.87514236
80MP0003868_abnormal_feces_composition0.87430030
81MP0003634_abnormal_glial_cell0.86849488
82MP0003890_abnormal_embryonic-extraembry0.86781975
83MP0002752_abnormal_somatic_nervous0.85963073
84MP0003119_abnormal_digestive_system0.85748566
85MP0006292_abnormal_olfactory_placode0.84339209
86MP0002653_abnormal_ependyma_morphology0.84271471
87MP0003633_abnormal_nervous_system0.83385905
88MP0004484_altered_response_of0.83213848
89MP0001879_abnormal_lymphatic_vessel0.81085521
90MP0002697_abnormal_eye_size0.80834559
91MP0005195_abnormal_posterior_eye0.80513517
92MP0001324_abnormal_eye_pigmentation0.80166791
93MP0005499_abnormal_olfactory_system0.80095168
94MP0005394_taste/olfaction_phenotype0.80095168
95MP0001485_abnormal_pinna_reflex0.79796875
96MP0000920_abnormal_myelination0.79501808
97MP0005167_abnormal_blood-brain_barrier0.78667906
98MP0003631_nervous_system_phenotype0.78406196
99MP0001963_abnormal_hearing_physiology0.78320094
100MP0005670_abnormal_white_adipose0.76352348
101MP0004133_heterotaxia0.76253713
102MP0001293_anophthalmia0.75563289
103MP0001177_atelectasis0.74916993
104MP0002751_abnormal_autonomic_nervous0.74783029
105MP0003195_calcinosis0.73881787
106MP0001958_emphysema0.73772895
107MP0004145_abnormal_muscle_electrophysio0.72929689
108MP0002102_abnormal_ear_morphology0.72908594
109MP0002069_abnormal_eating/drinking_beha0.72867347
110MP0002160_abnormal_reproductive_system0.72452337
111MP0000026_abnormal_inner_ear0.71924878
112MP0005646_abnormal_pituitary_gland0.71731009
113MP0004085_abnormal_heartbeat0.70914046
114MP0004233_abnormal_muscle_weight0.68965242
115MP0005367_renal/urinary_system_phenotyp0.68746170
116MP0000516_abnormal_urinary_system0.68746170
117MP0003632_abnormal_nervous_system0.68483508
118MP0008961_abnormal_basal_metabolism0.68237421
119MP0001943_abnormal_respiration0.66523976
120MP0001905_abnormal_dopamine_level0.65989397
121MP0002081_perinatal_lethality0.64815845
122MP0002229_neurodegeneration0.64335719
123MP0005248_abnormal_Harderian_gland0.64056308
124MP0004215_abnormal_myocardial_fiber0.63409125
125MP0004510_myositis0.59289104
126MP0003137_abnormal_impulse_conducting0.59236204
127MP0010770_preweaning_lethality0.58510184
128MP0002082_postnatal_lethality0.58510184
129MP0000604_amyloidosis0.57601842
130MP0003942_abnormal_urinary_system0.57194320
131MP0010769_abnormal_survival0.56295857
132MP0003755_abnormal_palate_morphology0.56155218

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.42664805
2Focal seizures (HP:0007359)4.10887337
3Epileptic encephalopathy (HP:0200134)3.59345440
4Myokymia (HP:0002411)3.49628190
5Progressive cerebellar ataxia (HP:0002073)3.40635173
6Atonic seizures (HP:0010819)3.33187262
7Visual hallucinations (HP:0002367)3.31531745
8Febrile seizures (HP:0002373)3.24638304
9Action tremor (HP:0002345)3.14433755
10Termporal pattern (HP:0011008)3.09746085
11Insidious onset (HP:0003587)3.09746085
12Broad-based gait (HP:0002136)3.01215532
13Absence seizures (HP:0002121)2.98398146
14Excessive salivation (HP:0003781)2.97637445
15Drooling (HP:0002307)2.97637445
16Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.95134987
17Degeneration of the lateral corticospinal tracts (HP:0002314)2.95134987
18Mutism (HP:0002300)2.85115535
19Genetic anticipation (HP:0003743)2.77201051
20Supranuclear gaze palsy (HP:0000605)2.76063375
21Dialeptic seizures (HP:0011146)2.62632495
22Amblyopia (HP:0000646)2.60343353
23Asymmetry of the thorax (HP:0001555)2.59263706
24Gaze-evoked nystagmus (HP:0000640)2.57808543
25Inappropriate behavior (HP:0000719)2.57622126
26Urinary bladder sphincter dysfunction (HP:0002839)2.55959816
27Generalized tonic-clonic seizures (HP:0002069)2.53200930
28Abnormality of the corticospinal tract (HP:0002492)2.49554528
29Polyphagia (HP:0002591)2.44413750
30Aplasia/Hypoplasia of the brainstem (HP:0007362)2.39813673
31Hypoplasia of the brainstem (HP:0002365)2.39813673
32Ankle clonus (HP:0011448)2.38354015
33Fetal akinesia sequence (HP:0001989)2.34163264
34Protruding tongue (HP:0010808)2.31069496
35Urinary urgency (HP:0000012)2.29418764
36Truncal ataxia (HP:0002078)2.29095761
37Abnormal eating behavior (HP:0100738)2.28232394
38Impaired vibration sensation in the lower limbs (HP:0002166)2.24080134
39Hyperventilation (HP:0002883)2.22705460
40Exotropia (HP:0000577)2.20294489
41Apathy (HP:0000741)2.19441623
42Aqueductal stenosis (HP:0002410)2.16140450
43Abnormality of the pubic bones (HP:0003172)2.14791792
44Absent speech (HP:0001344)2.14693971
45Genital tract atresia (HP:0001827)2.14380957
46Midline defect of the nose (HP:0004122)2.13906057
47Dysdiadochokinesis (HP:0002075)2.13186575
48Agitation (HP:0000713)2.12988773
49Amyotrophic lateral sclerosis (HP:0007354)2.12963854
50Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.12417634
51Hypsarrhythmia (HP:0002521)2.09107800
52Abnormality of salivation (HP:0100755)2.08388737
53Macroorchidism (HP:0000053)2.08280712
54Hyperthyroidism (HP:0000836)2.08217391
55Vaginal atresia (HP:0000148)2.06565571
56Lissencephaly (HP:0001339)2.05361178
57Abnormality of the lower motor neuron (HP:0002366)2.05044486
58Vitreoretinal degeneration (HP:0000655)2.04736897
59Absent eyebrow (HP:0002223)2.01882841
60Osteomalacia (HP:0002749)2.01879618
61Lower limb asymmetry (HP:0100559)2.01241212
62Hemiparesis (HP:0001269)2.00822285
63Buphthalmos (HP:0000557)2.00207598
64Volvulus (HP:0002580)1.99970701
65Epidermoid cyst (HP:0200040)1.98870326
66Wrist flexion contracture (HP:0001239)1.95367527
67Impaired smooth pursuit (HP:0007772)1.95340041
68Disinhibition (HP:0000734)1.92869697
69Thyroid carcinoma (HP:0002890)1.92379306
70Diminished motivation (HP:0000745)1.92367579
71Oligodactyly (hands) (HP:0001180)1.90864164
72Neonatal short-limb short stature (HP:0008921)1.90093170
73Hypoventilation (HP:0002791)1.89182209
74Stereotypic behavior (HP:0000733)1.89136091
75Poor eye contact (HP:0000817)1.85757738
76Abnormality of binocular vision (HP:0011514)1.85171592
77Diplopia (HP:0000651)1.85171592
78Fibular aplasia (HP:0002990)1.83761915
79Lymphangioma (HP:0100764)1.83527397
80Vertebral arch anomaly (HP:0008438)1.82992240
81Akinesia (HP:0002304)1.82737145
82Papilledema (HP:0001085)1.82137587
83Ulnar claw (HP:0001178)1.81968788
84Epileptiform EEG discharges (HP:0011182)1.80037889
85Medial flaring of the eyebrow (HP:0010747)1.78952411
86Cutaneous finger syndactyly (HP:0010554)1.78862835
87Lower limb muscle weakness (HP:0007340)1.78686481
88Neuronal loss in central nervous system (HP:0002529)1.77452316
89Failure to thrive in infancy (HP:0001531)1.76704863
90Alacrima (HP:0000522)1.75612493
91Spastic tetraplegia (HP:0002510)1.75422564
92Prominent supraorbital ridges (HP:0000336)1.75378035
93Arterial tortuosity (HP:0005116)1.75236684
94Congenital primary aphakia (HP:0007707)1.74815481
95Limb dystonia (HP:0002451)1.74132304
96Anophthalmia (HP:0000528)1.74100850
97EEG with generalized epileptiform discharges (HP:0011198)1.74001719
98Shoulder girdle muscle weakness (HP:0003547)1.73961161
99Abnormality of ocular smooth pursuit (HP:0000617)1.73267849
100Lower limb amyotrophy (HP:0007210)1.72806186
101Depression (HP:0000716)1.72663527
102Short 4th metacarpal (HP:0010044)1.72518494
103Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.72518494
104Specific learning disability (HP:0001328)1.71469509
105Cutaneous syndactyly (HP:0012725)1.71275403
106Supernumerary spleens (HP:0009799)1.71036275
107Heterotopia (HP:0002282)1.70333918
108Broad palm (HP:0001169)1.70030732
109Dysmetric saccades (HP:0000641)1.68759360
110Heterochromia iridis (HP:0001100)1.68562717
111Pointed chin (HP:0000307)1.67529250
112Gait imbalance (HP:0002141)1.67033472
113Widely spaced teeth (HP:0000687)1.66967565
114Open mouth (HP:0000194)1.66253092
115Nephronophthisis (HP:0000090)1.65005129
116Severe Myopia (HP:0011003)1.64258004
117Narrow nasal bridge (HP:0000446)1.64158809
118Cerebral inclusion bodies (HP:0100314)1.64016866
119Megalencephaly (HP:0001355)1.63584139
120Hepatoblastoma (HP:0002884)1.63380984
121Broad ribs (HP:0000885)1.63054184
122Spastic gait (HP:0002064)1.62849130
123Aplasia involving bones of the extremities (HP:0009825)1.62781744
124Aplasia involving bones of the upper limbs (HP:0009823)1.62781744
125Aplasia of the phalanges of the hand (HP:0009802)1.62781744
126Pachygyria (HP:0001302)1.62688886
127Abnormality of the ischium (HP:0003174)1.62654645
128Chronic hepatic failure (HP:0100626)1.62650421
129Scanning speech (HP:0002168)1.61684128
130Sacral dimple (HP:0000960)1.61625093
131Neurofibrillary tangles (HP:0002185)1.61596363
132Renal hypoplasia (HP:0000089)1.61386564
133Morphological abnormality of the pyramidal tract (HP:0002062)1.61304434
134Short foot (HP:0001773)1.60968025
135Papillary thyroid carcinoma (HP:0002895)1.60276360
136Nephrogenic diabetes insipidus (HP:0009806)1.59793805
137Optic nerve hypoplasia (HP:0000609)1.59596343
138Hypothermia (HP:0002045)1.59056666
139Neoplasm of the adrenal cortex (HP:0100641)1.58618469
140Progressive inability to walk (HP:0002505)1.58600181
141Abnormality of the wing of the ilium (HP:0011867)1.57278956
142Decreased muscle mass (HP:0003199)1.57128264
143Abnormal social behavior (HP:0012433)1.57104575
144Impaired social interactions (HP:0000735)1.57104575
145Pheochromocytoma (HP:0002666)1.55780532
146Postaxial hand polydactyly (HP:0001162)1.55456586
147Gastroesophageal reflux (HP:0002020)1.55175647
148Abnormality of the labia minora (HP:0012880)1.55151617
149Vascular tortuosity (HP:0004948)1.55051572

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.96246676
2NTRK33.16593467
3MAP3K93.10575163
4MAP3K42.84974411
5CASK2.66230966
6MINK12.63679861
7MAP2K72.40349161
8MAPK132.28899155
9KSR12.21253136
10DAPK22.20241642
11NTRK22.14778465
12PAK62.00182053
13MAP3K122.00114111
14SIK21.86149193
15STK38L1.79836789
16ERBB31.79097125
17EPHA41.78725726
18KSR21.69316582
19PLK21.60940261
20MAP2K41.59989681
21FRK1.51052153
22WNK31.51016967
23LATS21.50241390
24RIPK41.44776391
25EPHA31.39315541
26FGFR21.30178047
27DYRK21.25395401
28CDK51.24368278
29CAMKK11.22028320
30SGK21.19008123
31PNCK1.17877596
32AKT31.17067763
33PHKG11.15987974
34PHKG21.15987974
35ACVR1B1.15901977
36SGK4941.15301167
37SGK2231.15301167
38DAPK11.08546425
39UHMK11.08236957
40OXSR11.07372003
41BCR1.05841960
42CSNK1G21.05741705
43DDR21.04276770
44STK391.04133897
45NTRK11.04120584
46NLK1.03454677
47CAMK1G1.02499748
48TYRO31.01972446
49LMTK21.01848015
50SIK31.01615207
51PAK30.98784236
52EPHB20.95841788
53BMPR1B0.95499404
54STK380.94687989
55DYRK30.94606057
56RET0.93647924
57DYRK1A0.92816962
58PRPF4B0.92511598
59FER0.91294060
60PIK3CA0.90814970
61MAP3K20.90620039
62CDK190.90343783
63CCNB10.88176227
64SGK30.87593824
65PINK10.86252409
66CSNK1G10.85277409
67YES10.83153543
68CAMKK20.82616247
69PRKD30.79492555
70GRK50.79324745
71CDK180.79193763
72RIPK10.78781202
73TRIM280.77852500
74ERBB20.77496453
75PDGFRA0.75584472
76CDK140.74134389
77PTK2B0.73425117
78PRKCG0.73014165
79CSNK1A1L0.71568634
80CDK150.71444621
81SGK10.71122742
82CAMK2A0.68963113
83STK110.68405729
84TGFBR20.66896254
85STK30.65130460
86RPS6KA20.64305517
87SCYL20.63885705
88MARK20.63874426
89BRD40.63201090
90DYRK1B0.62194482
91FGFR10.61995198
92STK240.61714888
93PKN10.59546476
94CDK11A0.58098313
95PRKG10.57626343
96PRKCE0.56546375
97CAMK1D0.53974555
98WNK40.53972194
99CDK30.53810350
100CAMK40.53607425
101MAP3K60.52653677
102MKNK20.52499325
103MAP4K20.52442985
104MUSK0.51592691
105PRKCZ0.50014812
106ROCK10.49378894
107TNIK0.49286005
108FGR0.49204885
109LATS10.48956053
110DMPK0.48797279
111CSNK1G30.48414993
112CDC42BPA0.48271472
113PDGFRB0.48002405
114CSNK1E0.47826647
115WNK10.46603515
116FES0.46581786
117LIMK10.45097375
118TIE10.44494182
119MAPK120.44462734
120CAMK10.43827196
121CSNK1D0.42778194
122MAPK150.42001233
123BMPR20.41502985
124ADRBK10.40845223
125PRKACB0.39604182
126MAPK90.39292088
127MAPK100.39153788
128CAMK2B0.38665833
129FYN0.38570289
130FGFR30.38023197
131GRK70.37942975
132RPS6KA30.36748605
133MAPK80.35813361

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.09279568
2Synaptic vesicle cycle_Homo sapiens_hsa047212.64916663
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.15842356
4Circadian entrainment_Homo sapiens_hsa047132.09547801
5Long-term potentiation_Homo sapiens_hsa047202.09241009
6Glutamatergic synapse_Homo sapiens_hsa047242.03636776
7GABAergic synapse_Homo sapiens_hsa047271.87420377
8Morphine addiction_Homo sapiens_hsa050321.84484276
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.80228501
10Olfactory transduction_Homo sapiens_hsa047401.78608353
11Dopaminergic synapse_Homo sapiens_hsa047281.77159397
12Axon guidance_Homo sapiens_hsa043601.71886239
13Taste transduction_Homo sapiens_hsa047421.71050550
14Long-term depression_Homo sapiens_hsa047301.59881892
15Amphetamine addiction_Homo sapiens_hsa050311.59492194
16Salivary secretion_Homo sapiens_hsa049701.57300318
17Collecting duct acid secretion_Homo sapiens_hsa049661.56995628
18Renin secretion_Homo sapiens_hsa049241.56925257
19Fatty acid biosynthesis_Homo sapiens_hsa000611.56292608
20Cholinergic synapse_Homo sapiens_hsa047251.53413842
21Gastric acid secretion_Homo sapiens_hsa049711.50411531
22Insulin secretion_Homo sapiens_hsa049111.50160653
23Gap junction_Homo sapiens_hsa045401.45389109
24Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.43892938
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.43562947
26Oxytocin signaling pathway_Homo sapiens_hsa049211.42048288
27Serotonergic synapse_Homo sapiens_hsa047261.40785836
28GnRH signaling pathway_Homo sapiens_hsa049121.38019640
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.35225855
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.34735179
31Aldosterone synthesis and secretion_Homo sapiens_hsa049251.30269168
32Glioma_Homo sapiens_hsa052141.28266309
33Type II diabetes mellitus_Homo sapiens_hsa049301.26811877
34ErbB signaling pathway_Homo sapiens_hsa040121.26460876
35Cocaine addiction_Homo sapiens_hsa050301.22149418
36Dorso-ventral axis formation_Homo sapiens_hsa043201.20482806
37Complement and coagulation cascades_Homo sapiens_hsa046101.20243860
38Endometrial cancer_Homo sapiens_hsa052131.18638906
39Estrogen signaling pathway_Homo sapiens_hsa049151.18412852
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18053405
41Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.10404175
42Calcium signaling pathway_Homo sapiens_hsa040201.09704709
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08765051
44Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07274971
45Melanogenesis_Homo sapiens_hsa049161.04162410
46Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03159982
47Vibrio cholerae infection_Homo sapiens_hsa051101.02638235
48Colorectal cancer_Homo sapiens_hsa052101.02325144
49ABC transporters_Homo sapiens_hsa020101.02065649
50cAMP signaling pathway_Homo sapiens_hsa040241.01972582
51Histidine metabolism_Homo sapiens_hsa003401.01908228
52Basal cell carcinoma_Homo sapiens_hsa052171.00777885
53Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.98802749
54PPAR signaling pathway_Homo sapiens_hsa033200.98735413
55ECM-receptor interaction_Homo sapiens_hsa045120.94548888
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.94245491
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94160128
58Dilated cardiomyopathy_Homo sapiens_hsa054140.93730959
59Neurotrophin signaling pathway_Homo sapiens_hsa047220.92425575
60Steroid biosynthesis_Homo sapiens_hsa001000.90016655
61Renal cell carcinoma_Homo sapiens_hsa052110.88429242
62TGF-beta signaling pathway_Homo sapiens_hsa043500.87337199
63Oocyte meiosis_Homo sapiens_hsa041140.84770473
64MAPK signaling pathway_Homo sapiens_hsa040100.84564735
65VEGF signaling pathway_Homo sapiens_hsa043700.82629524
66Choline metabolism in cancer_Homo sapiens_hsa052310.82042128
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.81093062
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.80988324
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.79653398
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79029425
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78857433
72Circadian rhythm_Homo sapiens_hsa047100.77821492
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77728072
74Phototransduction_Homo sapiens_hsa047440.76528876
75Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75605617
76Phagosome_Homo sapiens_hsa041450.75455348
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.74715896
78mTOR signaling pathway_Homo sapiens_hsa041500.74007309
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73322000
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72897889
81Rap1 signaling pathway_Homo sapiens_hsa040150.72789290
82Wnt signaling pathway_Homo sapiens_hsa043100.72588107
83Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.72411107
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.71562859
85Ras signaling pathway_Homo sapiens_hsa040140.71432436
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.70043654
87Bile secretion_Homo sapiens_hsa049760.69556438
88Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68287202
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.67849334
90Cardiac muscle contraction_Homo sapiens_hsa042600.67325100
91Butanoate metabolism_Homo sapiens_hsa006500.67182684
92Hippo signaling pathway_Homo sapiens_hsa043900.67114547
93Thyroid hormone synthesis_Homo sapiens_hsa049180.64333240
94Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.64039160
95Pancreatic cancer_Homo sapiens_hsa052120.63863145
96Melanoma_Homo sapiens_hsa052180.63554497
97Fatty acid metabolism_Homo sapiens_hsa012120.63127266
98Inositol phosphate metabolism_Homo sapiens_hsa005620.62758891
99Glycerolipid metabolism_Homo sapiens_hsa005610.62552767
100Ovarian steroidogenesis_Homo sapiens_hsa049130.62544379
101Pancreatic secretion_Homo sapiens_hsa049720.62296551
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61045760
103Regulation of autophagy_Homo sapiens_hsa041400.60401099
104Focal adhesion_Homo sapiens_hsa045100.60179922
105Hedgehog signaling pathway_Homo sapiens_hsa043400.59611030
106beta-Alanine metabolism_Homo sapiens_hsa004100.59554993
107Viral myocarditis_Homo sapiens_hsa054160.58936057
108Fat digestion and absorption_Homo sapiens_hsa049750.58524187
109Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57645948
110Prolactin signaling pathway_Homo sapiens_hsa049170.57288129
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56901074
112Endocytosis_Homo sapiens_hsa041440.56255909
113Proteoglycans in cancer_Homo sapiens_hsa052050.55173912
114Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54914015
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54756376
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54754511
117Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54309303
118Protein digestion and absorption_Homo sapiens_hsa049740.54218775
119Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53682815
120Salmonella infection_Homo sapiens_hsa051320.53251270
121AMPK signaling pathway_Homo sapiens_hsa041520.52793438
122Insulin signaling pathway_Homo sapiens_hsa049100.52766855
123FoxO signaling pathway_Homo sapiens_hsa040680.52654744
124Phenylalanine metabolism_Homo sapiens_hsa003600.51397182
125Adherens junction_Homo sapiens_hsa045200.51365119
126Non-small cell lung cancer_Homo sapiens_hsa052230.51016376
127AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50900782
128Rheumatoid arthritis_Homo sapiens_hsa053230.50569372
129Tight junction_Homo sapiens_hsa045300.50506300
130Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50149088
131Nitrogen metabolism_Homo sapiens_hsa009100.49798070
132Ether lipid metabolism_Homo sapiens_hsa005650.48927990
133Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45322995

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